******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/ELF4.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr6:13815630-13815710 1.0000 80 chrX:2548924-2549004 1.0000 80 chr7:130692410-130692490 1.0000 80 chr22:22242758-22242838 1.0000 80 chr19:53445744-53445824 1.0000 80 chr6:150188560-150188640 1.0000 80 chrX:2547888-2547968 1.0000 80 chr10:73083301-73083381 1.0000 80 chr19:53228946-53229026 1.0000 80 chr8:120845289-120845369 1.0000 80 chr19:49479585-49479665 1.0000 80 chr10:62074241-62074321 1.0000 80 chr8:66556122-66556202 1.0000 80 chr11:46134682-46134762 1.0000 80 chr4:174089349-174089429 1.0000 80 chr10:25755019-25755099 1.0000 80 chr2:241500609-241500689 1.0000 80 chr20:45810082-45810162 1.0000 80 chr17:1227614-1227694 1.0000 80 chr20:2489731-2489811 1.0000 80 chr22:50201801-50201881 1.0000 80 chr10:104503393-10450347 1.0000 80 chr1:142891053-142891133 1.0000 80 chr2:133104958-133105038 1.0000 80 chr7:64467030-64467110 1.0000 80 chr19:46498421-46498501 1.0000 80 chr19:41082708-41082788 1.0000 80 chr12:54582872-54582952 1.0000 80 chrX:69353709-69353789 1.0000 80 chr5:82373371-82373451 1.0000 80 chr17:7358815-7358895 1.0000 80 chr19:55663509-55663589 1.0000 80 chr19:53073585-53073665 1.0000 80 chr1:12142006-12142086 1.0000 80 chr20:2083107-2083187 1.0000 80 chrX:2550381-2550461 1.0000 80 chr19:19475817-19475897 1.0000 80 chr9:132346516-132346596 1.0000 80 chr15:36871687-36871767 1.0000 80 chr17:48075811-48075891 1.0000 80 chr12:131239146-13123922 1.0000 80 chr1:154359179-154359259 1.0000 80 chr19:53238235-53238315 1.0000 80 chr19:44716566-44716646 1.0000 80 chr17:61904502-61904582 1.0000 80 chr20:33735143-33735223 1.0000 80 chr8:18067587-18067667 1.0000 80 chr19:53837001-53837081 1.0000 80 chr3:129118415-129118495 1.0000 80 chr9:97021546-97021626 1.0000 80 chr19:10028079-10028159 1.0000 80 chr1:206736422-206736502 1.0000 80 chr19:4815782-4815862 1.0000 80 chr7:38948757-38948837 1.0000 80 chr19:53289954-53290034 1.0000 80 chr11:75186587-75186667 1.0000 80 chr22:23096160-23096240 1.0000 80 chr16:77225000-77225080 1.0000 80 chr4:2470741-2470821 1.0000 80 chr1:231473691-231473771 1.0000 80 chr1:22755259-22755339 1.0000 80 chr5:151151060-151151140 1.0000 80 chr6:37786708-37786788 1.0000 80 chr19:19496520-19496600 1.0000 80 chr19:41084561-41084641 1.0000 80 chr12:108908906-10890898 1.0000 80 chr19:21203412-21203492 1.0000 80 chr19:16296086-16296166 1.0000 80 chr12:108955121-10895520 1.0000 80 chr15:37392534-37392614 1.0000 80 chr5:93447354-93447434 1.0000 80 chr19:53898414-53898494 1.0000 80 chr17:73452576-73452656 1.0000 80 chr20:18268884-18268964 1.0000 80 chr19:58326307-58326387 1.0000 80 chr16:31724509-31724589 1.0000 80 chr15:66874475-66874555 1.0000 80 chr13:114103569-11410364 1.0000 80 chr3:93781831-93781911 1.0000 80 chr1:113162850-113162930 1.0000 80 chr8:21776016-21776096 1.0000 80 chr10:114206819-11420689 1.0000 80 chr6:88182463-88182543 1.0000 80 chr19:21950341-21950421 1.0000 80 chr10:16859675-16859755 1.0000 80 chr4:140149020-140149100 1.0000 80 chr12:66524479-66524559 1.0000 80 chr19:58331032-58331112 1.0000 80 chr17:80163928-80164008 1.0000 80 chr2:131129522-131129602 1.0000 80 chr1:155211036-155211116 1.0000 80 chr2:88927163-88927243 1.0000 80 chr12:6798752-6798832 1.0000 80 chrX:134975765-134975845 1.0000 80 chr19:58361133-58361213 1.0000 80 chr7:153111148-153111228 1.0000 80 chrX:2549132-2549212 1.0000 80 chr14:73493969-73494049 1.0000 80 chr16:57769286-57769366 1.0000 80 chr15:64648491-64648571 1.0000 80 chr20:36007742-36007822 1.0000 80 chr17:40714336-40714416 1.0000 80 chr10:15902534-15902614 1.0000 80 chr1:222763258-222763338 1.0000 80 chr12:88535935-88536015 1.0000 80 chr16:30759395-30759475 1.0000 80 chr11:22647367-22647447 1.0000 80 chr6:160211426-160211506 1.0000 80 chr11:69197235-69197315 1.0000 80 chr19:58892658-58892738 1.0000 80 chr1:38388648-38388728 1.0000 80 chr7:111846540-111846620 1.0000 80 chrX:130037298-130037378 1.0000 80 chr12:56223382-56223462 1.0000 80 chrX:70585742-70585822 1.0000 80 chr8:120845082-120845162 1.0000 80 chr19:44669113-44669193 1.0000 80 chr5:130971248-130971328 1.0000 80 chr8:30601703-30601783 1.0000 80 chr19:44617461-44617541 1.0000 80 chr3:50397066-50397146 1.0000 80 chr20:10415819-10415899 1.0000 80 chr19:9251000-9251080 1.0000 80 chr1:160991249-160991329 1.0000 80 chr9:135282169-135282249 1.0000 80 chr6:3209665-3209745 1.0000 80 chr1:243418779-243418859 1.0000 80 chr19:44711545-44711625 1.0000 80 chr14:77924102-77924182 1.0000 80 chr19:6604106-6604186 1.0000 80 chr18:61089720-61089800 1.0000 80 chr17:4634684-4634764 1.0000 80 chr19:21512135-21512215 1.0000 80 chrX:153775809-153775889 1.0000 80 chr12:21654546-21654626 1.0000 80 chr13:41837711-41837791 1.0000 80 chr1:36335198-36335278 1.0000 80 chr5:93447555-93447635 1.0000 80 chr6:147523590-147523670 1.0000 80 chr16:25122889-25122969 1.0000 80 chr4:41937132-41937212 1.0000 80 chr9:102861346-102861426 1.0000 80 chr5:85913621-85913701 1.0000 80 chr16:15150041-15150121 1.0000 80 chr19:53141494-53141574 1.0000 80 chr11:60681347-60681427 1.0000 80 chr17:80408759-80408839 1.0000 80 chr7:150725390-150725470 1.0000 80 chr1:151227116-151227196 1.0000 80 chr16:4524664-4524744 1.0000 80 chr7:72298921-72299001 1.0000 80 chr12:46780166-46780246 1.0000 80 chr22:24372885-24372965 1.0000 80 chr19:44439447-44439527 1.0000 80 chr15:50716283-50716363 1.0000 80 chr1:203595772-203595852 1.0000 80 chr7:128546845-128546925 1.0000 80 chr19:46234182-46234262 1.0000 80 chr8:82754996-82755076 1.0000 80 chr11:109817122-10981720 1.0000 80 chr2:55459535-55459615 1.0000 80 chr16:30583338-30583418 1.0000 80 chr6:24721486-24721566 1.0000 80 chr16:30621736-30621816 1.0000 80 chr4:56719779-56719859 1.0000 80 chr10:32218421-32218501 1.0000 80 chr19:58427981-58428061 1.0000 80 chr9:104296049-104296129 1.0000 80 chr5:55008107-55008187 1.0000 80 chr19:44507037-44507117 1.0000 80 chr1:42922544-42922624 1.0000 80 chr15:91565805-91565885 1.0000 80 chr1:23694875-23694955 1.0000 80 chr11:94801860-94801940 1.0000 80 chrX:48432666-48432746 1.0000 80 chr19:4540251-4540331 1.0000 80 chr16:19535074-19535154 1.0000 80 chr17:34957975-34958055 1.0000 80 chr19:53606602-53606682 1.0000 80 chr19:46366545-46366625 1.0000 80 chr11:62521447-62521527 1.0000 80 chr2:66662211-66662291 1.0000 80 chr1:32355149-32355229 1.0000 80 chr2:133105157-133105237 1.0000 80 chr2:202097041-202097121 1.0000 80 chr19:56826375-56826455 1.0000 80 chr4:37003425-37003505 1.0000 80 chr12:50505684-50505764 1.0000 80 chr19:18133041-18133121 1.0000 80 chr19:7616378-7616458 1.0000 80 chr19:58144451-58144531 1.0000 80 chr2:180871960-180872040 1.0000 80 chr3:50388393-50388473 1.0000 80 chr17:47492356-47492436 1.0000 80 chr17:73780711-73780791 1.0000 80 chr1:33116122-33116202 1.0000 80 chr15:78832677-78832757 1.0000 80 chr16:28503412-28503492 1.0000 80 chr7:64363614-64363694 1.0000 80 chr17:38375418-38375498 1.0000 80 chr2:32502801-32502881 1.0000 80 chr6:8064746-8064826 1.0000 80 chr15:91473396-91473476 1.0000 80 chr9:130700152-130700232 1.0000 80 chr6:33257266-33257346 1.0000 80 chr16:84457296-84457376 1.0000 80 chr6:30484247-30484327 1.0000 80 chr2:201676445-201676525 1.0000 80 chr10:121356539-12135661 1.0000 80 chr6:33151081-33151161 1.0000 80 chr16:30366627-30366707 1.0000 80 chr8:18067812-18067892 1.0000 80 chr11:66247883-66247963 1.0000 80 chr1:213189206-213189286 1.0000 80 chr19:52598942-52599022 1.0000 80 chr4:140004101-140004181 1.0000 80 chr19:3990357-3990437 1.0000 80 chr1:95538380-95538460 1.0000 80 chr19:51963859-51963939 1.0000 80 chr19:54663684-54663764 1.0000 80 chr19:14192197-14192277 1.0000 80 chr8:102166127-102166207 1.0000 80 chr1:47780138-47780218 1.0000 80 chr19:3185476-3185556 1.0000 80 chr15:41099664-41099744 1.0000 80 chr22:20207353-20207433 1.0000 80 chr3:4781622-4781702 1.0000 80 chr2:178417572-178417652 1.0000 80 chr11:57434987-57435067 1.0000 80 chrX:950792-950872 1.0000 80 chr11:71639559-71639639 1.0000 80 chr18:55297496-55297576 1.0000 80 chr16:57219931-57220011 1.0000 80 chr17:12921504-12921584 1.0000 80 chr2:85822684-85822764 1.0000 80 chr10:131909480-13190956 1.0000 80 chr17:73975672-73975752 1.0000 80 chr7:100861306-100861386 1.0000 80 chr11:107436329-10743640 1.0000 80 chr22:27068806-27068886 1.0000 80 chr17:79212919-79212999 1.0000 80 chr19:36239283-36239363 1.0000 80 chrX:71792838-71792918 1.0000 80 chr17:8093570-8093650 1.0000 80 chr17:73390051-73390131 1.0000 80 chr20:44486063-44486143 1.0000 80 chr19:12780368-12780448 1.0000 80 chrX:155110888-155110968 1.0000 80 chr11:45939440-45939520 1.0000 80 chr14:21924335-21924415 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_ELF4/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/ELF4.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.222 C 0.272 G 0.285 T 0.222 Background letter frequencies (from file dataset with add-one prior applied): A 0.222 C 0.272 G 0.285 T 0.222 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF RCTTCCGG MEME-1 width = 8 sites = 136 llr = 996 E-value = 1.6e-082 ******************************************************************************** -------------------------------------------------------------------------------- Motif RCTTCCGG MEME-1 Description -------------------------------------------------------------------------------- Simplified A 6::::::: pos.-specific C :9::a912 probability G 3:::::67 matrix T 11aa:131 bits 2.2 ** 2.0 ** 1.7 *** 1.5 **** Relative 1.3 ***** Entropy 1.1 ***** (10.6 bits) 0.9 ***** 0.7 ****** * 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ACTTCCGG consensus G TC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTTCCGG MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:12921504-12921584 56 1.79e-05 CTGGGGCGGG ACTTCCGG AAGCACAGTG chr16:57219931-57220011 34 1.79e-05 GTCCCGCCCC ACTTCCGG CGACGTAACC chr6:33257266-33257346 64 1.79e-05 TCAGAAAGAA ACTTCCGG CACAGTCTT chr16:28503412-28503492 30 1.79e-05 GGTTTTCCCT ACTTCCGG GTCCTCTCTG chr2:66662211-66662291 30 1.79e-05 GGCCACCACT ACTTCCGG GTTCTAGCAT chr19:53606602-53606682 62 1.79e-05 CGCACGATCC ACTTCCGG GTCTGTGGGC chr1:42922544-42922624 64 1.79e-05 AGGAGAATGC ACTTCCGG GTTTTGCTG chr19:44507037-44507117 63 1.79e-05 AGACGCGAGC ACTTCCGG TGTGTGAGCC chr4:56719779-56719859 23 1.79e-05 TACGCGGTCA ACTTCCGG CGCGGAGTTT chr4:41937132-41937212 22 1.79e-05 TGAAAGGAGC ACTTCCGG GTTCGGCAAT chr1:36335198-36335278 49 1.79e-05 AAGAACTCAA ACTTCCGG CAGACTCGCG chr17:4634684-4634764 39 1.79e-05 ACCGAGAGCC ACTTCCGG AACAAGCGTC chr19:44669113-44669193 53 1.79e-05 AGTTGTAGGC ACTTCCGG CTCGAGGAAG chrX:70585742-70585822 20 1.79e-05 TCTTACCCTT ACTTCCGG GTATTGTGGT chr12:56223382-56223462 38 1.79e-05 GCCTACTTCC ACTTCCGG GGTCACCAGG chr6:160211426-160211506 46 1.79e-05 GGGACTTGCT ACTTCCGG GTCGGTGGCG chr16:30759395-30759475 64 1.79e-05 AGTAAACCCA ACTTCCGG GTCCCATTC chr19:58331032-58331112 50 1.79e-05 TAGGGCCGAG ACTTCCGG GGTCCTCTTG chr20:33735143-33735223 46 1.79e-05 TCAGCCTCTC ACTTCCGG ACTACAAGCC chr19:46498421-46498501 14 1.79e-05 TCAAGGGGCT ACTTCCGG GATTCTTTCC chr22:50201801-50201881 21 1.79e-05 tggcaatccc acttccgg gtatacaccc chr2:241500609-241500689 36 1.79e-05 GCAGAGAGGC ACTTCCGG GTTGGGCGGG chr19:53228946-53229026 62 1.79e-05 CACGTGATCC ACTTCCGG GTTTGCTGCG chr7:130692410-130692490 36 1.79e-05 GGAAGGCGCC ACTTCCGG GTCCGTGTCT chr22:20207353-20207433 22 3.18e-05 AAGGCGCTCC ACTTCCTG CTTTGGCTTA chr2:32502801-32502881 61 3.18e-05 TTACAAGTGA ACTTCCTG TCCTGGGTAA chr19:18133041-18133121 23 3.18e-05 ACCCAGATcc acttcctg gtttcctgtg chr1:32355149-32355229 73 3.18e-05 gtgagggccc acttcctg chr13:41837711-41837791 6 3.18e-05 CGTTC ACTTCCTG GTTCACTTCT chrX:2549132-2549212 68 3.18e-05 ACATTACAAC ACTTCCTG GTTCA chr15:36871687-36871767 53 3.18e-05 GGCGGCCGCT ACTTCCTG GTTGGTTTGC chr9:132346516-132346596 66 3.18e-05 ggtttggccc acttcctg ggagttt chrX:2550381-2550461 37 3.18e-05 TAATTGTAGC ACTTCCTG GTTCATAGGG chr1:12142006-12142086 58 3.18e-05 ctcttgcctc acttcctg cttcccttct chr19:55663509-55663589 68 3.18e-05 tccctcatgc acttcctg tcttt chr20:45810082-45810162 22 3.18e-05 cattctactc acttcctg ttagccccag chr4:174089349-174089429 24 3.18e-05 CGGTAGTCCC ACTTCCTG GTTGGCTTCC chr10:73083301-73083381 1 3.18e-05 . acttcctg gaagtaacat chrX:2547888-2547968 70 3.18e-05 TCATTGTGAC ACTTCCTG GTT chr6:150188560-150188640 43 3.18e-05 gtgagggccc acttcctg gttcatagac chrX:2548924-2549004 26 3.18e-05 TAATTGTAGC ACTTCCTG GTTCATAGGG chr11:45939440-45939520 1 5.48e-05 . GCTTCCGG TCTTAGGCCC chr17:73975672-73975752 14 5.48e-05 CCTCTGTCAC GCTTCCGG GTCCGTGCCC chr10:131909480-13190956 67 5.48e-05 GGGCTGCCTC GCTTCCGG GTGGGA chr19:52598942-52599022 65 5.48e-05 AGCGCGATCT GCTTCCGG GTGTGCAG chr7:64363614-64363694 12 5.48e-05 GGACAGGACG GCTTCCGG GATTTGGCGG chr17:80163928-80164008 24 5.48e-05 GGACCATGAA GCTTCCGG GTTGGGGAGC chr16:31724509-31724589 50 5.48e-05 AGCAGGGGCG GCTTCCGG GATTTGGCGG chr19:21203412-21203492 27 5.48e-05 GGACAGGGCG GCTTCCGG GTTTGGCGGG chr1:22755259-22755339 3 5.48e-05 ag gcttccgg gtataaagac chr19:53289954-53290034 63 5.48e-05 CACGCGATCC GCTTCCGG GTTTGTGCGC chr19:53238235-53238315 51 5.48e-05 CACCCGATCC GCTTCCGG GTTTGCGTTA chr17:1227614-1227694 52 5.48e-05 CCTCCGCCCT GCTTCCGG GGTCATCGCC chr2:85822684-85822764 51 7.18e-05 CCGAATTAGT ACTTCCGC TTTCCGTGCT chr18:55297496-55297576 38 7.18e-05 TCTCCGGGCC ACTTCCGC GTTTCTGGCG chr15:78832677-78832757 41 7.18e-05 CGCAAGAAGG ACTTCCGC GTCCTCGGCC chr1:33116122-33116202 71 7.18e-05 CGGAGTTACT ACTTCCGC TC chr11:22647367-22647447 8 7.18e-05 AGGCCCT ACTTCCGC TTTCACCTTG chr2:131129522-131129602 19 7.18e-05 CTTCTATGCC ACTTCCGC ATTCTTTTGT chr6:37786708-37786788 72 7.18e-05 CCAGAGCTCC ACTTCCGC G chr9:97021546-97021626 48 7.18e-05 CGGCTCGCGT ACTTCCGC GTTCCGGCAT chr2:133104958-133105038 30 7.18e-05 TAGTCGGGTA ACTTCCGC TCTAGGAGGC chr19:51963859-51963939 31 8.97e-05 ttccctgttt gcttcctg gacaaagttc chr19:4540251-4540331 20 8.97e-05 TTCTTTCCTT GCTTCCTG ATTTTTGGGG chr11:94801860-94801940 31 8.97e-05 GTGCTGAGCT GCTTCCTG TTTTCTTCTG chr19:4815782-4815862 71 8.97e-05 TGCACTTCCC GCTTCCTG TT chr19:10028079-10028159 36 8.97e-05 ttgcatactg gcttcctg gtcggtttat chr19:19475817-19475897 61 8.97e-05 gcgagggcct gcttcctg gttTGCTTCC chrX:48432666-48432746 48 1.04e-04 GAAACACCCC ATTTCCGG AAACACCCCA chr22:24372885-24372965 48 1.04e-04 AGACGACCGG ATTTCCGG AAATCAGAGC chr17:80408759-80408839 22 1.04e-04 AGCCGAGCGG ATTTCCGG GATCCGGGCG chr16:25122889-25122969 31 1.04e-04 CTATCGTCAA ATTTCCGG GTTATGTGGG chr17:73390051-73390131 33 1.18e-04 TCCTGAACAC ACTTCCTC TTCCTTCCCG chr8:18067587-18067667 31 1.18e-04 AAGTGAGAGC ACTTCCTC ATAGACCTTG chr9:130700152-130700232 4 1.35e-04 CGC TCTTCCGG CTTTGGACTG chr12:66524479-66524559 64 1.35e-04 TGCACTTCCG TCTTCCGG GCGGAGGCC chr1:154359179-154359259 29 1.35e-04 CTCCCTCTGG TCTTCCGG GTTCTGCGTT chrX:69353709-69353789 64 1.35e-04 GGAAAAGAGA TCTTCCGG GTTCCTCTC chr4:140004101-140004181 19 2.03e-04 CCCTGCGGCC ACTTCCGT GTTTACACTC chr10:121356539-12135661 7 2.03e-04 GAGGAG ACTTCTGG GTAGTGTAGT chr17:38375418-38375498 36 2.03e-04 CCACTCAACC GCTTCCGC CTTTACGTGG chr6:24721486-24721566 55 2.03e-04 ATGGAGTCGC ACTTCCCG AGTCTCGTCA chr11:109817122-10981720 25 2.03e-04 GAGACTCCAG GCTTCCGC ATTCCTCTGG chr7:72298921-72299001 55 2.03e-04 AGGGCGGAGC GCTTCCGC CTCCGTTTGG chr1:222763258-222763338 19 2.03e-04 CCCGGAAGTG ACTTCTGG AAGTGACCCA chr7:38948757-38948837 7 2.03e-04 TCCTCT GCTTCCGC CATGGCGCCA chr19:53073585-53073665 49 2.03e-04 TATCCCCGGC ACTTCCGT ACCTGGGACG chr10:104503393-10450347 51 2.03e-04 TTATGAAGCT GCTTCCGC CACTCTCTGC chr20:2489731-2489811 71 2.03e-04 CTCTGCGGCA GCTTCCGC AG chr10:62074241-62074321 34 2.03e-04 ATGAGGGCAC ACTTCTGG GAATCTGTGT chrX:130037298-130037378 17 2.42e-04 TGGAGGCTGT TCTTCCTG GGGGTAACTC chr19:36239283-36239363 42 2.61e-04 TAGATGGTTT GTTTCCGG AAGCAAAGCC chr16:4524664-4524744 21 2.61e-04 ACTCGGCGTC GTTTCCGG GTTTGCCCGC chr9:104296049-104296129 38 3.00e-04 GGTTGAAGCC ACTTCCTT TTTTCTTTCC chr9:102861346-102861426 56 3.00e-04 GTCATCTAGA ACTTCCTT TCCCATTGGG chr15:66874475-66874555 24 3.00e-04 cgcttttgct gcttcctc attctgtctt chr19:44711545-44711625 10 3.14e-04 CTCGGAAGT ATTTCCGC TCCAAGGAGC chr12:21654546-21654626 24 3.95e-04 GAGCATCCAC CCTTCCGG GTCGGTCCGT chr19:9251000-9251080 22 3.95e-04 tctccgcccc gcttccgt attagacgcc chr1:155211036-155211116 6 3.95e-04 TTCCG GCTTCCCG ATGTGGATGG chr10:25755019-25755099 55 3.95e-04 aaacagcaac ccttccgg gtcccttttc chr6:30484247-30484327 67 4.26e-04 CTCTGTCCCT GTTTCCTG GATAGG chr5:151151060-151151140 52 4.74e-04 CTAGGGGTTT ACTTCCCC AAAGTACACG chr16:30583338-30583418 59 5.59e-04 TAGAGGAGAG GCTTCTTG CCTTCAAGAA chr18:61089720-61089800 18 5.86e-04 TGCTCCGGGC ACTTCCGA TTTCGTCATC chr8:30601703-30601783 32 5.86e-04 GTTGGCATTT TCTTCCTC TCTGCTGTCC chr11:71639559-71639639 72 6.41e-04 AGGAAAATAC ATTTCCGT G chr19:58144451-58144531 54 6.41e-04 AGACAGGGGC ATTTCCGT GTGGGTCTAC chr6:147523590-147523670 44 6.41e-04 AGTGGACTAC ATTTCCCG AAATCCCTGG chr19:58892658-58892738 57 6.71e-04 CCCGGAACCG ACTTGCGG TTCGCAGGCT chrX:950792-950872 65 7.28e-04 ggcggctcca tcttcccg gcaggaac chr8:102166127-102166207 63 7.28e-04 ggcggggtgc atttccag gaagtgtgct chr15:64648491-64648571 63 7.28e-04 CACCCCCATT TCTTCTGG GACTACCAGA chr16:77225000-77225080 34 7.28e-04 ACCGGAAGTG TCTTCTGG GAGGGGTCGT chr14:21924335-21924415 36 8.62e-04 AAGCCCGGCC TCTTCCAG CGAGCTAGTG chr19:14192197-14192277 68 8.62e-04 GACGGGCACC ACTTCCCT TTTTG chr15:91565805-91565885 15 8.62e-04 AAAAGAAGCG ACTTCCTA GATCTCCCGG chr14:77924102-77924182 16 8.62e-04 TTCCGCGAGA CCTTCCGC GGTTATCCAG chr12:6798752-6798832 62 8.62e-04 GGCGGAAATA GCTTCTGC CCAGCGACTG chr11:57434987-57435067 59 9.48e-04 GCTTTTGAGT ACTTCTAG TACACACACA chr11:60681347-60681427 53 9.48e-04 AGGAGGATTA GCTTCCAC TCCGATTTCA chr19:12780368-12780448 21 9.88e-04 AAGCCAGAAG TCTTCCTT TCAAAGGGAA chr15:91473396-91473476 71 1.05e-03 GAGTCACCGA GTTTCCCG CG chr16:19535074-19535154 2 1.05e-03 C GTTTCCCG GCGTGCAGCG chr15:50716283-50716363 15 1.13e-03 GAGCAACCTT GCTTCTTC CACAACAAGG chr17:61904502-61904582 7 1.13e-03 TCGAGG TTTTCCGC CATTTTGAGT chr8:21776016-21776096 2 1.16e-03 a gtttccag gtgccctacc chr19:46366545-46366625 23 1.35e-03 TCCGGCTAGG CCTTCTGG GAAATGTAGT chr1:203595772-203595852 5 1.35e-03 GATT GCTTCCCT TTCTTTTCCC chr19:58326307-58326387 5 1.35e-03 CCTT ACTTGCGC ACACGGAAAC chr19:44716566-44716646 13 1.35e-03 GATGGTTTTT CCTTCTGG AAGTTCTGGG chr8:66556122-66556202 63 1.35e-03 CAGCCCAGCG ACCTCCGG GATCAATTGC chr19:58361133-58361213 47 1.43e-03 GAAAGAAGGC ATTTCCAC GTGTGCACGT chr1:206736422-206736502 55 1.43e-03 aatggtgggt gtttcttg caaccacggg chr20:2083107-2083187 34 1.51e-03 AAGGCGTGAA GCTTGCTG GCTCTTCTTT chr19:7616378-7616458 45 2.11e-03 TGGGAAATGG AGTTCCGC GAAGAAATCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTTCCGG MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:12921504-12921584 1.8e-05 55_[+1]_17 chr16:57219931-57220011 1.8e-05 33_[+1]_39 chr6:33257266-33257346 1.8e-05 63_[+1]_9 chr16:28503412-28503492 1.8e-05 29_[+1]_43 chr2:66662211-66662291 1.8e-05 29_[+1]_43 chr19:53606602-53606682 1.8e-05 61_[+1]_11 chr1:42922544-42922624 1.8e-05 63_[+1]_9 chr19:44507037-44507117 1.8e-05 62_[+1]_10 chr4:56719779-56719859 1.8e-05 22_[+1]_50 chr4:41937132-41937212 1.8e-05 21_[+1]_51 chr1:36335198-36335278 1.8e-05 48_[+1]_24 chr17:4634684-4634764 1.8e-05 38_[+1]_34 chr19:44669113-44669193 1.8e-05 52_[+1]_20 chrX:70585742-70585822 1.8e-05 19_[+1]_53 chr12:56223382-56223462 1.8e-05 37_[+1]_35 chr6:160211426-160211506 1.8e-05 45_[+1]_27 chr16:30759395-30759475 1.8e-05 63_[+1]_9 chr19:58331032-58331112 1.8e-05 49_[+1]_23 chr20:33735143-33735223 1.8e-05 45_[+1]_27 chr19:46498421-46498501 1.8e-05 13_[+1]_59 chr22:50201801-50201881 1.8e-05 20_[+1]_52 chr2:241500609-241500689 1.8e-05 35_[+1]_37 chr19:53228946-53229026 1.8e-05 61_[+1]_11 chr7:130692410-130692490 1.8e-05 35_[+1]_37 chr22:20207353-20207433 3.2e-05 21_[+1]_51 chr2:32502801-32502881 3.2e-05 60_[+1]_12 chr19:18133041-18133121 3.2e-05 22_[+1]_50 chr1:32355149-32355229 3.2e-05 72_[+1] chr13:41837711-41837791 3.2e-05 5_[+1]_67 chrX:2549132-2549212 3.2e-05 67_[+1]_5 chr15:36871687-36871767 3.2e-05 52_[+1]_20 chr9:132346516-132346596 3.2e-05 65_[+1]_7 chrX:2550381-2550461 3.2e-05 36_[+1]_36 chr1:12142006-12142086 3.2e-05 57_[+1]_15 chr19:55663509-55663589 3.2e-05 67_[+1]_5 chr20:45810082-45810162 3.2e-05 21_[+1]_51 chr4:174089349-174089429 3.2e-05 23_[+1]_49 chr10:73083301-73083381 3.2e-05 [+1]_72 chrX:2547888-2547968 3.2e-05 69_[+1]_3 chr6:150188560-150188640 3.2e-05 42_[+1]_30 chrX:2548924-2549004 3.2e-05 25_[+1]_47 chr11:45939440-45939520 5.5e-05 [+1]_72 chr17:73975672-73975752 5.5e-05 13_[+1]_59 chr10:131909480-13190956 5.5e-05 66_[+1]_6 chr19:52598942-52599022 5.5e-05 64_[+1]_8 chr7:64363614-64363694 5.5e-05 11_[+1]_61 chr17:80163928-80164008 5.5e-05 23_[+1]_49 chr16:31724509-31724589 5.5e-05 49_[+1]_23 chr19:21203412-21203492 5.5e-05 26_[+1]_46 chr1:22755259-22755339 5.5e-05 2_[+1]_70 chr19:53289954-53290034 5.5e-05 62_[+1]_10 chr19:53238235-53238315 5.5e-05 50_[+1]_22 chr17:1227614-1227694 5.5e-05 51_[+1]_21 chr2:85822684-85822764 7.2e-05 50_[+1]_22 chr18:55297496-55297576 7.2e-05 37_[+1]_35 chr15:78832677-78832757 7.2e-05 40_[+1]_32 chr1:33116122-33116202 7.2e-05 70_[+1]_2 chr11:22647367-22647447 7.2e-05 7_[+1]_65 chr2:131129522-131129602 7.2e-05 18_[+1]_54 chr6:37786708-37786788 7.2e-05 71_[+1]_1 chr9:97021546-97021626 7.2e-05 47_[+1]_25 chr2:133104958-133105038 7.2e-05 29_[+1]_43 chr19:51963859-51963939 9e-05 30_[+1]_42 chr19:4540251-4540331 9e-05 19_[+1]_53 chr11:94801860-94801940 9e-05 30_[+1]_42 chr19:4815782-4815862 9e-05 70_[+1]_2 chr19:10028079-10028159 9e-05 35_[+1]_37 chr19:19475817-19475897 9e-05 60_[+1]_12 chrX:48432666-48432746 0.0001 47_[+1]_25 chr22:24372885-24372965 0.0001 47_[+1]_25 chr17:80408759-80408839 0.0001 21_[+1]_51 chr16:25122889-25122969 0.0001 30_[+1]_42 chr17:73390051-73390131 0.00012 32_[+1]_40 chr8:18067587-18067667 0.00012 30_[+1]_42 chr9:130700152-130700232 0.00014 3_[+1]_69 chr12:66524479-66524559 0.00014 63_[+1]_9 chr1:154359179-154359259 0.00014 28_[+1]_44 chrX:69353709-69353789 0.00014 63_[+1]_9 chr4:140004101-140004181 0.0002 18_[+1]_54 chr10:121356539-12135661 0.0002 6_[+1]_66 chr17:38375418-38375498 0.0002 35_[+1]_37 chr6:24721486-24721566 0.0002 54_[+1]_18 chr11:109817122-10981720 0.0002 24_[+1]_48 chr7:72298921-72299001 0.0002 54_[+1]_18 chr1:222763258-222763338 0.0002 18_[+1]_54 chr7:38948757-38948837 0.0002 6_[+1]_66 chr19:53073585-53073665 0.0002 48_[+1]_24 chr10:104503393-10450347 0.0002 50_[+1]_22 chr20:2489731-2489811 0.0002 70_[+1]_2 chr10:62074241-62074321 0.0002 33_[+1]_39 chrX:130037298-130037378 0.00024 16_[+1]_56 chr19:36239283-36239363 0.00026 41_[+1]_31 chr16:4524664-4524744 0.00026 20_[+1]_52 chr9:104296049-104296129 0.0003 37_[+1]_35 chr9:102861346-102861426 0.0003 55_[+1]_17 chr15:66874475-66874555 0.0003 23_[+1]_49 chr19:44711545-44711625 0.00031 9_[+1]_63 chr12:21654546-21654626 0.00039 23_[+1]_49 chr19:9251000-9251080 0.00039 21_[+1]_51 chr1:155211036-155211116 0.00039 5_[+1]_67 chr10:25755019-25755099 0.00039 54_[+1]_18 chr6:30484247-30484327 0.00043 66_[+1]_6 chr5:151151060-151151140 0.00047 51_[+1]_21 chr16:30583338-30583418 0.00056 58_[+1]_14 chr18:61089720-61089800 0.00059 17_[+1]_55 chr8:30601703-30601783 0.00059 31_[+1]_41 chr11:71639559-71639639 0.00064 71_[+1]_1 chr19:58144451-58144531 0.00064 53_[+1]_19 chr6:147523590-147523670 0.00064 43_[+1]_29 chr19:58892658-58892738 0.00067 56_[+1]_16 chrX:950792-950872 0.00073 64_[+1]_8 chr8:102166127-102166207 0.00073 62_[+1]_10 chr15:64648491-64648571 0.00073 62_[+1]_10 chr16:77225000-77225080 0.00073 33_[+1]_39 chr14:21924335-21924415 0.00086 35_[+1]_37 chr19:14192197-14192277 0.00086 67_[+1]_5 chr15:91565805-91565885 0.00086 14_[+1]_58 chr14:77924102-77924182 0.00086 15_[+1]_57 chr12:6798752-6798832 0.00086 61_[+1]_11 chr11:57434987-57435067 0.00095 58_[+1]_14 chr11:60681347-60681427 0.00095 52_[+1]_20 chr19:12780368-12780448 0.00099 20_[+1]_52 chr15:91473396-91473476 0.0011 70_[+1]_2 chr16:19535074-19535154 0.0011 1_[+1]_71 chr15:50716283-50716363 0.0011 14_[+1]_58 chr17:61904502-61904582 0.0011 6_[+1]_66 chr8:21776016-21776096 0.0012 1_[+1]_71 chr19:46366545-46366625 0.0013 22_[+1]_50 chr1:203595772-203595852 0.0013 4_[+1]_68 chr19:58326307-58326387 0.0013 4_[+1]_68 chr19:44716566-44716646 0.0013 12_[+1]_60 chr8:66556122-66556202 0.0013 62_[+1]_10 chr19:58361133-58361213 0.0014 46_[+1]_26 chr1:206736422-206736502 0.0014 54_[+1]_18 chr20:2083107-2083187 0.0015 33_[+1]_39 chr19:7616378-7616458 0.0021 44_[+1]_28 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTTCCGG MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RCTTCCGG width=8 seqs=136 chr17:12921504-12921584 ( 56) ACTTCCGG 1 chr16:57219931-57220011 ( 34) ACTTCCGG 1 chr6:33257266-33257346 ( 64) ACTTCCGG 1 chr16:28503412-28503492 ( 30) ACTTCCGG 1 chr2:66662211-66662291 ( 30) ACTTCCGG 1 chr19:53606602-53606682 ( 62) ACTTCCGG 1 chr1:42922544-42922624 ( 64) ACTTCCGG 1 chr19:44507037-44507117 ( 63) ACTTCCGG 1 chr4:56719779-56719859 ( 23) ACTTCCGG 1 chr4:41937132-41937212 ( 22) ACTTCCGG 1 chr1:36335198-36335278 ( 49) ACTTCCGG 1 chr17:4634684-4634764 ( 39) ACTTCCGG 1 chr19:44669113-44669193 ( 53) ACTTCCGG 1 chrX:70585742-70585822 ( 20) ACTTCCGG 1 chr12:56223382-56223462 ( 38) ACTTCCGG 1 chr6:160211426-160211506 ( 46) ACTTCCGG 1 chr16:30759395-30759475 ( 64) ACTTCCGG 1 chr19:58331032-58331112 ( 50) ACTTCCGG 1 chr20:33735143-33735223 ( 46) ACTTCCGG 1 chr19:46498421-46498501 ( 14) ACTTCCGG 1 chr22:50201801-50201881 ( 21) ACTTCCGG 1 chr2:241500609-241500689 ( 36) ACTTCCGG 1 chr19:53228946-53229026 ( 62) ACTTCCGG 1 chr7:130692410-130692490 ( 36) ACTTCCGG 1 chr22:20207353-20207433 ( 22) ACTTCCTG 1 chr2:32502801-32502881 ( 61) ACTTCCTG 1 chr19:18133041-18133121 ( 23) ACTTCCTG 1 chr1:32355149-32355229 ( 73) ACTTCCTG 1 chr13:41837711-41837791 ( 6) ACTTCCTG 1 chrX:2549132-2549212 ( 68) ACTTCCTG 1 chr15:36871687-36871767 ( 53) ACTTCCTG 1 chr9:132346516-132346596 ( 66) ACTTCCTG 1 chrX:2550381-2550461 ( 37) ACTTCCTG 1 chr1:12142006-12142086 ( 58) ACTTCCTG 1 chr19:55663509-55663589 ( 68) ACTTCCTG 1 chr20:45810082-45810162 ( 22) ACTTCCTG 1 chr4:174089349-174089429 ( 24) ACTTCCTG 1 chr10:73083301-73083381 ( 1) ACTTCCTG 1 chrX:2547888-2547968 ( 70) ACTTCCTG 1 chr6:150188560-150188640 ( 43) ACTTCCTG 1 chrX:2548924-2549004 ( 26) ACTTCCTG 1 chr11:45939440-45939520 ( 1) GCTTCCGG 1 chr17:73975672-73975752 ( 14) GCTTCCGG 1 chr10:131909480-13190956 ( 67) GCTTCCGG 1 chr19:52598942-52599022 ( 65) GCTTCCGG 1 chr7:64363614-64363694 ( 12) GCTTCCGG 1 chr17:80163928-80164008 ( 24) GCTTCCGG 1 chr16:31724509-31724589 ( 50) GCTTCCGG 1 chr19:21203412-21203492 ( 27) GCTTCCGG 1 chr1:22755259-22755339 ( 3) GCTTCCGG 1 chr19:53289954-53290034 ( 63) GCTTCCGG 1 chr19:53238235-53238315 ( 51) GCTTCCGG 1 chr17:1227614-1227694 ( 52) GCTTCCGG 1 chr2:85822684-85822764 ( 51) ACTTCCGC 1 chr18:55297496-55297576 ( 38) ACTTCCGC 1 chr15:78832677-78832757 ( 41) ACTTCCGC 1 chr1:33116122-33116202 ( 71) ACTTCCGC 1 chr11:22647367-22647447 ( 8) ACTTCCGC 1 chr2:131129522-131129602 ( 19) ACTTCCGC 1 chr6:37786708-37786788 ( 72) ACTTCCGC 1 chr9:97021546-97021626 ( 48) ACTTCCGC 1 chr2:133104958-133105038 ( 30) ACTTCCGC 1 chr19:51963859-51963939 ( 31) GCTTCCTG 1 chr19:4540251-4540331 ( 20) GCTTCCTG 1 chr11:94801860-94801940 ( 31) GCTTCCTG 1 chr19:4815782-4815862 ( 71) GCTTCCTG 1 chr19:10028079-10028159 ( 36) GCTTCCTG 1 chr19:19475817-19475897 ( 61) GCTTCCTG 1 chrX:48432666-48432746 ( 48) ATTTCCGG 1 chr22:24372885-24372965 ( 48) ATTTCCGG 1 chr17:80408759-80408839 ( 22) ATTTCCGG 1 chr16:25122889-25122969 ( 31) ATTTCCGG 1 chr17:73390051-73390131 ( 33) ACTTCCTC 1 chr8:18067587-18067667 ( 31) ACTTCCTC 1 chr9:130700152-130700232 ( 4) TCTTCCGG 1 chr12:66524479-66524559 ( 64) TCTTCCGG 1 chr1:154359179-154359259 ( 29) TCTTCCGG 1 chrX:69353709-69353789 ( 64) TCTTCCGG 1 chr4:140004101-140004181 ( 19) ACTTCCGT 1 chr10:121356539-12135661 ( 7) ACTTCTGG 1 chr17:38375418-38375498 ( 36) GCTTCCGC 1 chr6:24721486-24721566 ( 55) ACTTCCCG 1 chr11:109817122-10981720 ( 25) GCTTCCGC 1 chr7:72298921-72299001 ( 55) GCTTCCGC 1 chr1:222763258-222763338 ( 19) ACTTCTGG 1 chr7:38948757-38948837 ( 7) GCTTCCGC 1 chr19:53073585-53073665 ( 49) ACTTCCGT 1 chr10:104503393-10450347 ( 51) GCTTCCGC 1 chr20:2489731-2489811 ( 71) GCTTCCGC 1 chr10:62074241-62074321 ( 34) ACTTCTGG 1 chrX:130037298-130037378 ( 17) TCTTCCTG 1 chr19:36239283-36239363 ( 42) GTTTCCGG 1 chr16:4524664-4524744 ( 21) GTTTCCGG 1 chr9:104296049-104296129 ( 38) ACTTCCTT 1 chr9:102861346-102861426 ( 56) ACTTCCTT 1 chr15:66874475-66874555 ( 24) GCTTCCTC 1 chr19:44711545-44711625 ( 10) ATTTCCGC 1 chr12:21654546-21654626 ( 24) CCTTCCGG 1 chr19:9251000-9251080 ( 22) GCTTCCGT 1 chr1:155211036-155211116 ( 6) GCTTCCCG 1 chr10:25755019-25755099 ( 55) CCTTCCGG 1 chr6:30484247-30484327 ( 67) GTTTCCTG 1 chr5:151151060-151151140 ( 52) ACTTCCCC 1 chr16:30583338-30583418 ( 59) GCTTCTTG 1 chr18:61089720-61089800 ( 18) ACTTCCGA 1 chr8:30601703-30601783 ( 32) TCTTCCTC 1 chr11:71639559-71639639 ( 72) ATTTCCGT 1 chr19:58144451-58144531 ( 54) ATTTCCGT 1 chr6:147523590-147523670 ( 44) ATTTCCCG 1 chr19:58892658-58892738 ( 57) ACTTGCGG 1 chrX:950792-950872 ( 65) TCTTCCCG 1 chr8:102166127-102166207 ( 63) ATTTCCAG 1 chr15:64648491-64648571 ( 63) TCTTCTGG 1 chr16:77225000-77225080 ( 34) TCTTCTGG 1 chr14:21924335-21924415 ( 36) TCTTCCAG 1 chr19:14192197-14192277 ( 68) ACTTCCCT 1 chr15:91565805-91565885 ( 15) ACTTCCTA 1 chr14:77924102-77924182 ( 16) CCTTCCGC 1 chr12:6798752-6798832 ( 62) GCTTCTGC 1 chr11:57434987-57435067 ( 59) ACTTCTAG 1 chr11:60681347-60681427 ( 53) GCTTCCAC 1 chr19:12780368-12780448 ( 21) TCTTCCTT 1 chr15:91473396-91473476 ( 71) GTTTCCCG 1 chr16:19535074-19535154 ( 2) GTTTCCCG 1 chr15:50716283-50716363 ( 15) GCTTCTTC 1 chr17:61904502-61904582 ( 7) TTTTCCGC 1 chr8:21776016-21776096 ( 2) GTTTCCAG 1 chr19:46366545-46366625 ( 23) CCTTCTGG 1 chr1:203595772-203595852 ( 5) GCTTCCCT 1 chr19:58326307-58326387 ( 5) ACTTGCGC 1 chr19:44716566-44716646 ( 13) CCTTCTGG 1 chr8:66556122-66556202 ( 63) ACCTCCGG 1 chr19:58361133-58361213 ( 47) ATTTCCAC 1 chr1:206736422-206736502 ( 55) GTTTCTTG 1 chr20:2083107-2083187 ( 34) GCTTGCTG 1 chr19:7616378-7616458 ( 45) AGTTCCGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTTCCGG MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 7.12741 E= 1.6e-082 139 -288 5 -133 -1373 166 -527 -75 -1373 -520 -1373 216 -1373 -1373 -1373 217 -1373 185 -369 -1373 -1373 175 -1373 -133 -233 -204 112 29 -391 -35 130 -159 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTTCCGG MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 136 E= 1.6e-082 0.580882 0.036765 0.294118 0.088235 0.000000 0.860294 0.007353 0.132353 0.000000 0.007353 0.000000 0.992647 0.000000 0.000000 0.000000 1.000000 0.000000 0.977941 0.022059 0.000000 0.000000 0.911765 0.000000 0.088235 0.044118 0.066176 0.617647 0.272059 0.014706 0.213235 0.698529 0.073529 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTTCCGG MEME-1 regular expression -------------------------------------------------------------------------------- [AG]CTTCC[GT][GC] -------------------------------------------------------------------------------- Time 4.90 secs. ******************************************************************************** ******************************************************************************** MOTIF CMGGAAGT MEME-2 width = 8 sites = 87 llr = 704 E-value = 5.7e-054 ******************************************************************************** -------------------------------------------------------------------------------- Motif CMGGAAGT MEME-2 Description -------------------------------------------------------------------------------- Simplified A :3::aa21 pos.-specific C 87:::::2 probability G 2:aa::8: matrix T :::::::7 bits 2.2 ** 2.0 ** 1.7 **** 1.5 **** Relative 1.3 **** Entropy 1.1 ****** (11.7 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCGGAAGT consensus A C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMGGAAGT MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:27068806-27068886 51 1.87e-05 ATTTCTGACA CCGGAAGT CAGTGAGAGG chr1:47780138-47780218 21 1.87e-05 GCAGATGAAG CCGGAAGT GCTCTATAAG chr16:30366627-30366707 21 1.87e-05 CCCGGGAAGC CCGGAAGT GGCTTCACTC chr15:91565805-91565885 29 1.87e-05 CCTAGATCTC CCGGAAGT CCCTTTCGCT chr10:32218421-32218501 29 1.87e-05 AGCACCGAAC CCGGAAGT AACAGCTTTG chr9:135282169-135282249 39 1.87e-05 TTCTCCCAAC CCGGAAGT GCTGCTGTTG chr7:111846540-111846620 38 1.87e-05 CCTCCCCATC CCGGAAGT GGGCGCGGCA chr11:69197235-69197315 48 1.87e-05 agcagaggga ccggaagt gcgcctgccc chr1:222763258-222763338 10 1.87e-05 GCCTCGACC CCGGAAGT GACTTCTGGA chr10:15902534-15902614 40 1.87e-05 AGTCCCCTCC CCGGAAGT GAAATTGGAG chr12:66524479-66524559 43 1.87e-05 CTCACGCCGA CCGGAAGT CTTTGCACTT chr3:93781831-93781911 51 1.87e-05 CCCGCGAATC CCGGAAGT CAGACTGTTT chr19:16296086-16296166 19 1.87e-05 CGCCCACTAC CCGGAAGT GTGGCCCGGG chr19:19496520-19496600 66 1.87e-05 GCGCCTCAAC CCGGAAGT GTGCGAG chr16:77225000-77225080 54 1.87e-05 GGGGTCGTAC CCGGAAGT GTGGCACCTC chr22:23096160-23096240 16 1.87e-05 CACCTAGACC CCGGAAGT CCCTGAGCTC chr17:48075811-48075891 12 1.87e-05 CTGGGAAGAC CCGGAAGT GGGTCACCTG chr5:82373371-82373451 71 1.87e-05 GAGGTAGGAT CCGGAAGT GG chr19:41082708-41082788 59 1.87e-05 GGGTGCACAC CCGGAAGT GGGTGCGGGC chr14:21924335-21924415 65 3.40e-05 GAGCGCCATC CAGGAAGT CTCTTGAG chr17:8093570-8093650 39 3.40e-05 TCGCGGCGAC CAGGAAGT CCCGGAAGAA chr3:4781622-4781702 41 3.40e-05 tttcaagaag caggaagt ggaagctact chr11:66247883-66247963 18 3.40e-05 GAGCCGGAAG CAGGAAGT GAGTTTGCGA chr6:33151081-33151161 21 3.40e-05 AAAGAGGATC CAGGAAGT GAACCTTCAA chr10:121356539-12135661 48 3.40e-05 GTGCGACGAC CAGGAAGT CGGCGGGCTG chr16:84457296-84457376 19 3.40e-05 aggcatagac caggaagt ggaatcatca chr1:203595772-203595852 42 3.40e-05 TAAGACGAAC CAGGAAGT AACCGCAAGA chr16:15150041-15150121 16 3.40e-05 AGTCCAAAGC CAGGAAGT GGCCCTGGAA chr8:120845082-120845162 44 3.40e-05 GGGGTAGAAC CAGGAAGT CTTGTCAATG chr20:36007742-36007822 50 3.40e-05 GCCCCAGAAC CAGGAAGT GCAAGGATAG chr1:155211036-155211116 55 3.40e-05 TCACATGACA CAGGAAGT GAGGCAATCA chr12:108955121-10895520 69 3.40e-05 GGTCTTTGGG CAGGAAGT GGAA chr11:75186587-75186667 62 3.40e-05 gGCTGGGAAC CAGGAAGT AGGAGGAGAC chr12:131239146-13123922 59 3.40e-05 agcaaaggag caggaagt aaagcaggaa chr15:50716283-50716363 53 4.86e-05 GCCTTGCAAC CCGGAAAT GCAGGGTGCA chr7:153111148-153111228 22 4.86e-05 aaaggtgaac ccggaaat gctgagtcag chr12:108908906-10890898 52 4.86e-05 ACGCGGGAAC CCGGAAAT GCGAGGGAAG chr7:38948757-38948837 46 4.86e-05 CCTGACAGAC CCGGAAAT AAGAGGAAAC chr1:206736422-206736502 40 4.86e-05 tgggccagac ccggaaat ggtgggtgtt chr17:12921504-12921584 28 9.12e-05 GCAATTTTTT CCGGAAGC TGTTTTTCTC chr12:50505684-50505764 69 9.12e-05 GATAACGGGC CCGGAAGC CGGA chr17:34957975-34958055 41 9.12e-05 GCTCCCGAAC CCGGAAGC GAGGGACCCA chr19:44439447-44439527 63 9.12e-05 CGCCCCCTGG GCGGAAGT GCGGGCTTCG chrX:153775809-153775889 31 9.12e-05 ACACCGGAAG CCGGAAGC GTGGTAGGGA chr19:21512135-21512215 39 9.12e-05 CGCGCCAAAC CCGGAAGC CGCCCTGTCC chr5:130971248-130971328 62 9.12e-05 CTTTGAATAT GCGGAAGT AGAAGCCGCC chr15:64648491-64648571 30 9.12e-05 GGGTTGCTAA GCGGAAGT GCCTTCAAAG chr4:140149020-140149100 52 9.12e-05 GCACAGGAAT GCGGAAGT AGTGGAAGTA chr10:16859675-16859755 50 9.12e-05 AGGGCTGTGG GCGGAAGT GGGGAAGTTT chr19:21950341-21950421 51 9.12e-05 CCCGCCAAAC CCGGAAGC CGTCCAGTCC chr1:231473691-231473771 38 9.12e-05 ATGAGCTATT GCGGAAGT GAGGGGAGGG chr4:2470741-2470821 29 9.12e-05 CCGGCCGACC GCGGAAGT AGAGTAGGCG chr19:53837001-53837081 5 9.12e-05 AAAC CCGGAAGC GGATCGCATG chr7:64467030-64467110 52 9.12e-05 CCCACCAAAC CCGGAAGC CGTCCTGTCT chr10:62074241-62074321 12 1.03e-04 CTAGGCCAGA CAGGAAAT GCAAATGAGG chr19:36239283-36239363 17 1.57e-04 CTACACCTCC CAGGAAGC TAGGGGGTAG chr2:202097041-202097121 51 1.57e-04 gcaccagaac ccggaaga gaaatccagt chr5:55008107-55008187 38 1.57e-04 CTAGTCCAAA CAGGAAGC GGCAATAGCC chr6:3209665-3209745 28 1.57e-04 TCAGGAGAAC CCGGAAGA AGTAGGAAGA chr1:160991249-160991329 34 1.57e-04 TACCTCTAAG GAGGAAGT AGGAAAGGCA chr1:38388648-38388728 52 1.57e-04 AAGAGCAAAC CAGGAAGC GGGGAGGGCA chrX:134975765-134975845 47 1.57e-04 gcgggagaac caggaagc gcagctctcc chr4:37003425-37003505 49 1.72e-04 cctaccctgg caggaaga cacgtacccg chr8:21776016-21776096 29 1.72e-04 ctctgcaaac caggaaga cctactagga chrX:48432666-48432746 35 2.05e-04 GACCCCATTT CCGGAAAC ACCCCATTTC chr12:6798752-6798832 53 2.05e-04 ATAACTCGGG GCGGAAAT AGCTTCTGCC chr5:93447354-93447434 63 2.05e-04 CGGCGACAAC CCGGAAAC GGGCGGGGCG chr19:44716566-44716646 52 2.05e-04 AGAACTCTGT CCGGAAAC AATTGGGCCG chr10:25755019-25755099 41 2.05e-04 gacacccaag ccggaaac agcaaccctt chr1:151227116-151227196 29 2.29e-04 GGGGACGGAG GCGGAAGC AGCTGGCCAA chr6:147523590-147523670 21 2.29e-04 GTCCTGGGAT GCGGAAGC TGCAGAGTGG chr1:213189206-213189286 12 2.59e-04 ATGCCTTAAC CCGGAATT CTGCTCAAGG chr12:46780166-46780246 63 3.01e-04 tacttttaat gAGGAAAT ATTTCGTATA chrX:69353709-69353789 52 3.01e-04 GCCTTTGACC CCGGAAAA GAGATCTTCC chr19:54663684-54663764 59 3.40e-04 AAGTCTCCTT GCGGAAGA GCGCTCTGCA chr1:36335198-36335278 35 3.40e-04 GCCTTGGGAA GCGGAAGA ACTCAAACTT chr17:7358815-7358895 24 3.40e-04 AGAAGAGTGT GCGGAAGA AGCGGCCCAT chr19:6604106-6604186 38 3.80e-04 cttccttttc aaggaagt gcttgcgcta chr19:44711545-44711625 2 3.80e-04 C TCGGAAGT ATTTCCGCTC chr19:44617461-44617541 59 3.80e-04 CAGTTTGTCT CAGGAATT CTGGGAAGTG chr19:41084561-41084641 37 3.80e-04 GATGCTTGGA AAGGAAGT TGGACACAGC chr11:71639559-71639639 61 3.92e-04 GTGCTGCAGC CAGGAAAA TACATTTCCG chr13:114103569-11410364 42 4.32e-04 AGAGACACAC CCGGAAGG AGTGAGCCCC chr12:54582872-54582952 11 4.32e-04 TGCTCCAATC CCGGAAGG CGCACTAAAT chr4:56719779-56719859 57 4.44e-04 TGCCCGGATA TAGGAAGT GTTGGGGGAA chr4:41937132-41937212 5 4.94e-04 CCCC ACGGAAAT GAAAGGAGCA chr5:93447555-93447635 44 5.46e-04 CGTTTTCCCA GCGGAATT TTAACTATTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMGGAAGT MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:27068806-27068886 1.9e-05 50_[+2]_22 chr1:47780138-47780218 1.9e-05 20_[+2]_52 chr16:30366627-30366707 1.9e-05 20_[+2]_52 chr15:91565805-91565885 1.9e-05 28_[+2]_44 chr10:32218421-32218501 1.9e-05 28_[+2]_44 chr9:135282169-135282249 1.9e-05 38_[+2]_34 chr7:111846540-111846620 1.9e-05 37_[+2]_35 chr11:69197235-69197315 1.9e-05 47_[+2]_25 chr1:222763258-222763338 1.9e-05 9_[+2]_63 chr10:15902534-15902614 1.9e-05 39_[+2]_33 chr12:66524479-66524559 1.9e-05 42_[+2]_30 chr3:93781831-93781911 1.9e-05 50_[+2]_22 chr19:16296086-16296166 1.9e-05 18_[+2]_54 chr19:19496520-19496600 1.9e-05 65_[+2]_7 chr16:77225000-77225080 1.9e-05 53_[+2]_19 chr22:23096160-23096240 1.9e-05 15_[+2]_57 chr17:48075811-48075891 1.9e-05 11_[+2]_61 chr5:82373371-82373451 1.9e-05 70_[+2]_2 chr19:41082708-41082788 1.9e-05 58_[+2]_14 chr14:21924335-21924415 3.4e-05 64_[+2]_8 chr17:8093570-8093650 3.4e-05 38_[+2]_34 chr3:4781622-4781702 3.4e-05 40_[+2]_32 chr11:66247883-66247963 3.4e-05 17_[+2]_55 chr6:33151081-33151161 3.4e-05 20_[+2]_52 chr10:121356539-12135661 3.4e-05 47_[+2]_25 chr16:84457296-84457376 3.4e-05 18_[+2]_54 chr1:203595772-203595852 3.4e-05 41_[+2]_31 chr16:15150041-15150121 3.4e-05 15_[+2]_57 chr8:120845082-120845162 3.4e-05 43_[+2]_29 chr20:36007742-36007822 3.4e-05 49_[+2]_23 chr1:155211036-155211116 3.4e-05 54_[+2]_18 chr12:108955121-10895520 3.4e-05 68_[+2]_4 chr11:75186587-75186667 3.4e-05 61_[+2]_11 chr12:131239146-13123922 3.4e-05 58_[+2]_14 chr15:50716283-50716363 4.9e-05 52_[+2]_20 chr7:153111148-153111228 4.9e-05 21_[+2]_51 chr12:108908906-10890898 4.9e-05 51_[+2]_21 chr7:38948757-38948837 4.9e-05 45_[+2]_27 chr1:206736422-206736502 4.9e-05 39_[+2]_33 chr17:12921504-12921584 9.1e-05 27_[+2]_45 chr12:50505684-50505764 9.1e-05 68_[+2]_4 chr17:34957975-34958055 9.1e-05 40_[+2]_32 chr19:44439447-44439527 9.1e-05 62_[+2]_10 chrX:153775809-153775889 9.1e-05 30_[+2]_42 chr19:21512135-21512215 9.1e-05 38_[+2]_34 chr5:130971248-130971328 9.1e-05 61_[+2]_11 chr15:64648491-64648571 9.1e-05 29_[+2]_43 chr4:140149020-140149100 9.1e-05 51_[+2]_21 chr10:16859675-16859755 9.1e-05 49_[+2]_23 chr19:21950341-21950421 9.1e-05 50_[+2]_22 chr1:231473691-231473771 9.1e-05 37_[+2]_35 chr4:2470741-2470821 9.1e-05 28_[+2]_44 chr19:53837001-53837081 9.1e-05 4_[+2]_68 chr7:64467030-64467110 9.1e-05 51_[+2]_21 chr10:62074241-62074321 0.0001 11_[+2]_61 chr19:36239283-36239363 0.00016 16_[+2]_56 chr2:202097041-202097121 0.00016 50_[+2]_22 chr5:55008107-55008187 0.00016 37_[+2]_35 chr6:3209665-3209745 0.00016 27_[+2]_45 chr1:160991249-160991329 0.00016 33_[+2]_39 chr1:38388648-38388728 0.00016 51_[+2]_21 chrX:134975765-134975845 0.00016 46_[+2]_26 chr4:37003425-37003505 0.00017 48_[+2]_24 chr8:21776016-21776096 0.00017 28_[+2]_44 chrX:48432666-48432746 0.00021 34_[+2]_38 chr12:6798752-6798832 0.00021 52_[+2]_20 chr5:93447354-93447434 0.00021 62_[+2]_10 chr19:44716566-44716646 0.00021 51_[+2]_21 chr10:25755019-25755099 0.00021 40_[+2]_32 chr1:151227116-151227196 0.00023 28_[+2]_44 chr6:147523590-147523670 0.00023 20_[+2]_52 chr1:213189206-213189286 0.00026 11_[+2]_61 chr12:46780166-46780246 0.0003 62_[+2]_10 chrX:69353709-69353789 0.0003 51_[+2]_21 chr19:54663684-54663764 0.00034 58_[+2]_14 chr1:36335198-36335278 0.00034 34_[+2]_38 chr17:7358815-7358895 0.00034 23_[+2]_49 chr19:6604106-6604186 0.00038 37_[+2]_35 chr19:44711545-44711625 0.00038 1_[+2]_71 chr19:44617461-44617541 0.00038 58_[+2]_14 chr19:41084561-41084641 0.00038 36_[+2]_36 chr11:71639559-71639639 0.00039 60_[+2]_12 chr13:114103569-11410364 0.00043 41_[+2]_31 chr12:54582872-54582952 0.00043 10_[+2]_62 chr4:56719779-56719859 0.00044 56_[+2]_16 chr4:41937132-41937212 0.00049 4_[+2]_68 chr5:93447555-93447635 0.00055 43_[+2]_29 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMGGAAGT MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CMGGAAGT width=8 seqs=87 chr22:27068806-27068886 ( 51) CCGGAAGT 1 chr1:47780138-47780218 ( 21) CCGGAAGT 1 chr16:30366627-30366707 ( 21) CCGGAAGT 1 chr15:91565805-91565885 ( 29) CCGGAAGT 1 chr10:32218421-32218501 ( 29) CCGGAAGT 1 chr9:135282169-135282249 ( 39) CCGGAAGT 1 chr7:111846540-111846620 ( 38) CCGGAAGT 1 chr11:69197235-69197315 ( 48) CCGGAAGT 1 chr1:222763258-222763338 ( 10) CCGGAAGT 1 chr10:15902534-15902614 ( 40) CCGGAAGT 1 chr12:66524479-66524559 ( 43) CCGGAAGT 1 chr3:93781831-93781911 ( 51) CCGGAAGT 1 chr19:16296086-16296166 ( 19) CCGGAAGT 1 chr19:19496520-19496600 ( 66) CCGGAAGT 1 chr16:77225000-77225080 ( 54) CCGGAAGT 1 chr22:23096160-23096240 ( 16) CCGGAAGT 1 chr17:48075811-48075891 ( 12) CCGGAAGT 1 chr5:82373371-82373451 ( 71) CCGGAAGT 1 chr19:41082708-41082788 ( 59) CCGGAAGT 1 chr14:21924335-21924415 ( 65) CAGGAAGT 1 chr17:8093570-8093650 ( 39) CAGGAAGT 1 chr3:4781622-4781702 ( 41) CAGGAAGT 1 chr11:66247883-66247963 ( 18) CAGGAAGT 1 chr6:33151081-33151161 ( 21) CAGGAAGT 1 chr10:121356539-12135661 ( 48) CAGGAAGT 1 chr16:84457296-84457376 ( 19) CAGGAAGT 1 chr1:203595772-203595852 ( 42) CAGGAAGT 1 chr16:15150041-15150121 ( 16) CAGGAAGT 1 chr8:120845082-120845162 ( 44) CAGGAAGT 1 chr20:36007742-36007822 ( 50) CAGGAAGT 1 chr1:155211036-155211116 ( 55) CAGGAAGT 1 chr12:108955121-10895520 ( 69) CAGGAAGT 1 chr11:75186587-75186667 ( 62) CAGGAAGT 1 chr12:131239146-13123922 ( 59) CAGGAAGT 1 chr15:50716283-50716363 ( 53) CCGGAAAT 1 chr7:153111148-153111228 ( 22) CCGGAAAT 1 chr12:108908906-10890898 ( 52) CCGGAAAT 1 chr7:38948757-38948837 ( 46) CCGGAAAT 1 chr1:206736422-206736502 ( 40) CCGGAAAT 1 chr17:12921504-12921584 ( 28) CCGGAAGC 1 chr12:50505684-50505764 ( 69) CCGGAAGC 1 chr17:34957975-34958055 ( 41) CCGGAAGC 1 chr19:44439447-44439527 ( 63) GCGGAAGT 1 chrX:153775809-153775889 ( 31) CCGGAAGC 1 chr19:21512135-21512215 ( 39) CCGGAAGC 1 chr5:130971248-130971328 ( 62) GCGGAAGT 1 chr15:64648491-64648571 ( 30) GCGGAAGT 1 chr4:140149020-140149100 ( 52) GCGGAAGT 1 chr10:16859675-16859755 ( 50) GCGGAAGT 1 chr19:21950341-21950421 ( 51) CCGGAAGC 1 chr1:231473691-231473771 ( 38) GCGGAAGT 1 chr4:2470741-2470821 ( 29) GCGGAAGT 1 chr19:53837001-53837081 ( 5) CCGGAAGC 1 chr7:64467030-64467110 ( 52) CCGGAAGC 1 chr10:62074241-62074321 ( 12) CAGGAAAT 1 chr19:36239283-36239363 ( 17) CAGGAAGC 1 chr2:202097041-202097121 ( 51) CCGGAAGA 1 chr5:55008107-55008187 ( 38) CAGGAAGC 1 chr6:3209665-3209745 ( 28) CCGGAAGA 1 chr1:160991249-160991329 ( 34) GAGGAAGT 1 chr1:38388648-38388728 ( 52) CAGGAAGC 1 chrX:134975765-134975845 ( 47) CAGGAAGC 1 chr4:37003425-37003505 ( 49) CAGGAAGA 1 chr8:21776016-21776096 ( 29) CAGGAAGA 1 chrX:48432666-48432746 ( 35) CCGGAAAC 1 chr12:6798752-6798832 ( 53) GCGGAAAT 1 chr5:93447354-93447434 ( 63) CCGGAAAC 1 chr19:44716566-44716646 ( 52) CCGGAAAC 1 chr10:25755019-25755099 ( 41) CCGGAAAC 1 chr1:151227116-151227196 ( 29) GCGGAAGC 1 chr6:147523590-147523670 ( 21) GCGGAAGC 1 chr1:213189206-213189286 ( 12) CCGGAATT 1 chr12:46780166-46780246 ( 63) GAGGAAAT 1 chrX:69353709-69353789 ( 52) CCGGAAAA 1 chr19:54663684-54663764 ( 59) GCGGAAGA 1 chr1:36335198-36335278 ( 35) GCGGAAGA 1 chr17:7358815-7358895 ( 24) GCGGAAGA 1 chr19:6604106-6604186 ( 38) AAGGAAGT 1 chr19:44711545-44711625 ( 2) TCGGAAGT 1 chr19:44617461-44617541 ( 59) CAGGAATT 1 chr19:41084561-41084641 ( 37) AAGGAAGT 1 chr11:71639559-71639639 ( 61) CAGGAAAA 1 chr13:114103569-11410364 ( 42) CCGGAAGG 1 chr12:54582872-54582952 ( 11) CCGGAAGG 1 chr4:56719779-56719859 ( 57) TAGGAAGT 1 chr4:41937132-41937212 ( 5) ACGGAAAT 1 chr5:93447555-93447635 ( 44) GCGGAATT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMGGAAGT MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.23674 E= 5.7e-054 -269 148 -63 -327 59 130 -1309 -1309 -1309 -1309 181 -1309 -1309 -1309 181 -1309 217 -1309 -1309 -1309 217 -1309 -1309 -1309 -36 -1309 148 -269 -110 -39 -363 159 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMGGAAGT MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 87 E= 5.7e-054 0.034483 0.758621 0.183908 0.022989 0.333333 0.666667 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.172414 0.000000 0.793103 0.034483 0.103448 0.206897 0.022989 0.666667 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMGGAAGT MEME-2 regular expression -------------------------------------------------------------------------------- C[CA]GGAAG[TC] -------------------------------------------------------------------------------- Time 8.48 secs. ******************************************************************************** ******************************************************************************** MOTIF AAKTGWAG MEME-3 width = 8 sites = 28 llr = 247 E-value = 1.4e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAKTGWAG MEME-3 Description -------------------------------------------------------------------------------- Simplified A aa23:4a: pos.-specific C :::::::: probability G ::4:a1:a matrix T ::58:5:: bits 2.2 ** * 2.0 ** * 1.7 ** * ** 1.5 ** * ** Relative 1.3 ** ** ** Entropy 1.1 ** ** ** (12.7 bits) 0.9 ** ** ** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AATTGTAG consensus GA A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAKTGWAG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:111846540-111846620 13 9.72e-06 GCACGCTGGG AATTGTAG TTCTTGGCCT chrX:2549132-2549212 5 9.72e-06 GGAT AATTGTAG CACTTCCTGG chrX:2550381-2550461 28 9.72e-06 TCATACAGAT AATTGTAG CACTTCCTGG chr12:54582872-54582952 49 9.72e-06 GATCGCTGGG AATTGTAG TTTAATCTTT chrX:2547888-2547968 33 9.72e-06 TCATATGGAT AATTGTAG CACTTCTTAG chrX:2548924-2549004 17 9.72e-06 TCATATGGAT AATTGTAG CACTTCCTGG chr19:46234182-46234262 22 1.94e-05 GCCCGCTGGG AATTGAAG TCCGGGCAGC chr3:93781831-93781911 7 1.94e-05 GCGAGA AATTGAAG AGGAAACGTG chr16:15150041-15150121 72 3.19e-05 GGGCGCTGGG AAGTGTAG T chr19:44711545-44711625 63 3.19e-05 GCATTCTGGG AAGTGTAG TCAGGGGCCC chr19:44617461-44617541 16 3.19e-05 GAATTCTGGG AAGTGTAG TCCAGACGCT chr20:18268884-18268964 19 3.19e-05 GGTCACTGGG AAGTGTAG TTTTCGAGAC chr19:3990357-3990437 72 5.41e-05 ggttggtggg aaatgtag t chr19:46366545-46366625 32 5.41e-05 GCCTTCTGGG AAATGTAG TCCCTTCGGA chr9:102861346-102861426 7 5.41e-05 TTCGGG AAATGTAG TCCTGCACTA chr19:6604106-6604186 7 5.41e-05 gtcaaa aagtgaag ggaagcaact chr1:243418779-243418859 42 5.41e-05 CGCCAACTCC AAGTGAAG GTCCGGTTGC chr17:79212919-79212999 39 9.58e-05 CTTCGTAAAC AATTGGAG CCTAGGCCAA chr19:18133041-18133121 64 9.58e-05 acacttggcc aattggag ccttttgtt chr19:53141494-53141574 51 9.58e-05 GCGCAGACTT AATAGAAG AGCGAAACTC chr1:36335198-36335278 12 9.58e-05 gttatgcctt aatagaag ttgGGGCCTT chr10:15902534-15902614 50 9.58e-05 CCGGAAGTGA AATTGGAG GCGGAAACAG chr2:180871960-180872040 55 1.46e-04 GGCGACAAAA AAGAGAAG TTGGCATGAA chr2:202097041-202097121 34 1.46e-04 taagagcagg aagagaag caccagaacc chr19:44507037-44507117 29 1.46e-04 GAATTCTGGG AAGTGGAG TCCAGACGCT chr1:38388648-38388728 29 1.46e-04 ATAAAGCTAA AAGAGAAG TGGGCAAGAG chr6:13815630-13815710 17 1.46e-04 aggttggtgc aaaagtag ttgcggcttt chr15:91565805-91565885 5 1.69e-04 CAGA AAAAGAAG CGACTTCCTA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAKTGWAG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:111846540-111846620 9.7e-06 12_[+3]_60 chrX:2549132-2549212 9.7e-06 4_[+3]_68 chrX:2550381-2550461 9.7e-06 27_[+3]_45 chr12:54582872-54582952 9.7e-06 48_[+3]_24 chrX:2547888-2547968 9.7e-06 32_[+3]_40 chrX:2548924-2549004 9.7e-06 16_[+3]_56 chr19:46234182-46234262 1.9e-05 21_[+3]_51 chr3:93781831-93781911 1.9e-05 6_[+3]_66 chr16:15150041-15150121 3.2e-05 71_[+3]_1 chr19:44711545-44711625 3.2e-05 62_[+3]_10 chr19:44617461-44617541 3.2e-05 15_[+3]_57 chr20:18268884-18268964 3.2e-05 18_[+3]_54 chr19:3990357-3990437 5.4e-05 71_[+3]_1 chr19:46366545-46366625 5.4e-05 31_[+3]_41 chr9:102861346-102861426 5.4e-05 6_[+3]_66 chr19:6604106-6604186 5.4e-05 6_[+3]_66 chr1:243418779-243418859 5.4e-05 41_[+3]_31 chr17:79212919-79212999 9.6e-05 38_[+3]_34 chr19:18133041-18133121 9.6e-05 63_[+3]_9 chr19:53141494-53141574 9.6e-05 50_[+3]_22 chr1:36335198-36335278 9.6e-05 11_[+3]_61 chr10:15902534-15902614 9.6e-05 49_[+3]_23 chr2:180871960-180872040 0.00015 54_[+3]_18 chr2:202097041-202097121 0.00015 33_[+3]_39 chr19:44507037-44507117 0.00015 28_[+3]_44 chr1:38388648-38388728 0.00015 28_[+3]_44 chr6:13815630-13815710 0.00015 16_[+3]_56 chr15:91565805-91565885 0.00017 4_[+3]_68 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAKTGWAG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAKTGWAG width=8 seqs=28 chr7:111846540-111846620 ( 13) AATTGTAG 1 chrX:2549132-2549212 ( 5) AATTGTAG 1 chrX:2550381-2550461 ( 28) AATTGTAG 1 chr12:54582872-54582952 ( 49) AATTGTAG 1 chrX:2547888-2547968 ( 33) AATTGTAG 1 chrX:2548924-2549004 ( 17) AATTGTAG 1 chr19:46234182-46234262 ( 22) AATTGAAG 1 chr3:93781831-93781911 ( 7) AATTGAAG 1 chr16:15150041-15150121 ( 72) AAGTGTAG 1 chr19:44711545-44711625 ( 63) AAGTGTAG 1 chr19:44617461-44617541 ( 16) AAGTGTAG 1 chr20:18268884-18268964 ( 19) AAGTGTAG 1 chr19:3990357-3990437 ( 72) AAATGTAG 1 chr19:46366545-46366625 ( 32) AAATGTAG 1 chr9:102861346-102861426 ( 7) AAATGTAG 1 chr19:6604106-6604186 ( 7) AAGTGAAG 1 chr1:243418779-243418859 ( 42) AAGTGAAG 1 chr17:79212919-79212999 ( 39) AATTGGAG 1 chr19:18133041-18133121 ( 64) AATTGGAG 1 chr19:53141494-53141574 ( 51) AATAGAAG 1 chr1:36335198-36335278 ( 12) AATAGAAG 1 chr10:15902534-15902614 ( 50) AATTGGAG 1 chr2:180871960-180872040 ( 55) AAGAGAAG 1 chr2:202097041-202097121 ( 34) AAGAGAAG 1 chr19:44507037-44507117 ( 29) AAGTGGAG 1 chr1:38388648-38388728 ( 29) AAGAGAAG 1 chr6:13815630-13815710 ( 17) AAAAGTAG 1 chr15:91565805-91565885 ( 5) AAAAGAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAKTGWAG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.95252 E= 1.4e-002 217 -1145 -1145 -1145 217 -1145 -1145 -1145 -31 -1145 33 106 17 -1145 -1145 176 -1145 -1145 181 -1145 69 -1145 -99 117 217 -1145 -1145 -1145 -1145 -1145 181 -1145 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAKTGWAG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 28 E= 1.4e-002 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.178571 0.000000 0.357143 0.464286 0.250000 0.000000 0.000000 0.750000 0.000000 0.000000 1.000000 0.000000 0.357143 0.000000 0.142857 0.500000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAKTGWAG MEME-3 regular expression -------------------------------------------------------------------------------- AA[TG][TA]G[TA]AG -------------------------------------------------------------------------------- Time 11.91 secs. ******************************************************************************** ******************************************************************************** MOTIF RRACTACA MEME-4 width = 8 sites = 17 llr = 170 E-value = 1.7e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif RRACTACA MEME-4 Description -------------------------------------------------------------------------------- Simplified A 45a::a:a pos.-specific C :::a::a: probability G 65:::::: matrix T ::::a::: bits 2.2 * ** * 2.0 ****** 1.7 ****** 1.5 ****** Relative 1.3 ****** Entropy 1.1 ******** (14.5 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GAACTACA consensus AG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRACTACA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:36239283-36239363 4 1.14e-05 CTG GAACTACA CCTCCCAGGA chr6:33257266-33257346 32 1.14e-05 AAACATGTCA GAACTACA CTTCCCATCA chr17:47492356-47492436 12 1.14e-05 CTTAGCAGAT GAACTACA ACTCCCAAAA chr2:180871960-180872040 70 1.14e-05 AAGTTGGCAT GAACTACA AAG chr19:44439447-44439527 7 1.14e-05 GCTCTG GAACTACA TTTCCCAGCA chr11:60681347-60681427 8 1.14e-05 AGCTCTA GAACTACA TGACCCAAAA chr5:85913621-85913701 60 1.14e-05 GCAATGGTCT GAACTACA ATTCCCACAA chr3:50397066-50397146 12 1.14e-05 GTTCTGGCTA GAACTACA AGTCCCAGGA chr19:3185476-3185556 44 3.48e-05 GTGTTTGACG GGACTACA ACTCCCAGAA chr19:46234182-46234262 43 3.48e-05 GGGCAGCCAC GGACTACA TCCCCCAGAA chr1:243418779-243418859 7 3.48e-05 CAACAA GGACTACA GTTCCCAGCG chr19:10028079-10028159 4 3.48e-05 aga aaactaca tttcccagat chr8:82754996-82755076 29 4.62e-05 AAACAGGAGA AGACTACA ATTCCCAGAA chr14:77924102-77924182 48 4.62e-05 TCACGTAGCA AGACTACA ATTCCCATGA chr1:22755259-22755339 17 4.62e-05 ccgggtataa agactaca tttcccagca chr7:64467030-64467110 1 4.62e-05 . AGACTACA CCAGAAGCTC chr20:2489731-2489811 41 4.62e-05 TGCAAAAAAA AGACTACA CTCCCCACAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRACTACA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:36239283-36239363 1.1e-05 3_[+4]_69 chr6:33257266-33257346 1.1e-05 31_[+4]_41 chr17:47492356-47492436 1.1e-05 11_[+4]_61 chr2:180871960-180872040 1.1e-05 69_[+4]_3 chr19:44439447-44439527 1.1e-05 6_[+4]_66 chr11:60681347-60681427 1.1e-05 7_[+4]_65 chr5:85913621-85913701 1.1e-05 59_[+4]_13 chr3:50397066-50397146 1.1e-05 11_[+4]_61 chr19:3185476-3185556 3.5e-05 43_[+4]_29 chr19:46234182-46234262 3.5e-05 42_[+4]_30 chr1:243418779-243418859 3.5e-05 6_[+4]_66 chr19:10028079-10028159 3.5e-05 3_[+4]_69 chr8:82754996-82755076 4.6e-05 28_[+4]_44 chr14:77924102-77924182 4.6e-05 47_[+4]_25 chr1:22755259-22755339 4.6e-05 16_[+4]_56 chr7:64467030-64467110 4.6e-05 [+4]_72 chr20:2489731-2489811 4.6e-05 40_[+4]_32 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRACTACA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RRACTACA width=8 seqs=17 chr19:36239283-36239363 ( 4) GAACTACA 1 chr6:33257266-33257346 ( 32) GAACTACA 1 chr17:47492356-47492436 ( 12) GAACTACA 1 chr2:180871960-180872040 ( 70) GAACTACA 1 chr19:44439447-44439527 ( 7) GAACTACA 1 chr11:60681347-60681427 ( 8) GAACTACA 1 chr5:85913621-85913701 ( 60) GAACTACA 1 chr3:50397066-50397146 ( 12) GAACTACA 1 chr19:3185476-3185556 ( 44) GGACTACA 1 chr19:46234182-46234262 ( 43) GGACTACA 1 chr1:243418779-243418859 ( 7) GGACTACA 1 chr19:10028079-10028159 ( 4) AAACTACA 1 chr8:82754996-82755076 ( 29) AGACTACA 1 chr14:77924102-77924182 ( 48) AGACTACA 1 chr1:22755259-22755339 ( 17) AGACTACA 1 chr7:64467030-64467110 ( 1) AGACTACA 1 chr20:2489731-2489811 ( 41) AGACTACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRACTACA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8621 E= 1.7e-002 67 -1073 118 -1073 125 -1073 73 -1073 217 -1073 -1073 -1073 -1073 188 -1073 -1073 -1073 -1073 -1073 217 217 -1073 -1073 -1073 -1073 188 -1073 -1073 217 -1073 -1073 -1073 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRACTACA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 17 E= 1.7e-002 0.352941 0.000000 0.647059 0.000000 0.529412 0.000000 0.470588 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RRACTACA MEME-4 regular expression -------------------------------------------------------------------------------- [GA][AG]ACTACA -------------------------------------------------------------------------------- Time 15.29 secs. ******************************************************************************** ******************************************************************************** MOTIF TCCCAGVA MEME-5 width = 8 sites = 31 llr = 256 E-value = 2.4e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCCCAGVA MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::3a:48 pos.-specific C :aa7::2: probability G :::::842 matrix T a::::21: bits 2.2 * * 2.0 *** * 1.7 *** * 1.5 *** * Relative 1.3 *** * * Entropy 1.1 ****** * (11.9 bits) 0.9 ****** * 0.7 ****** * 0.4 ****** * 0.2 ******** 0.0 -------- Multilevel TCCCAGAA consensus A TG sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCAGVA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:3185476-3185556 54 1.39e-05 GGACTACAAC TCCCAGAA GACCTAGCGC chr19:51963859-51963939 8 1.39e-05 ctacaat tcccagaa tccccttccc chr8:82754996-82755076 39 1.39e-05 AGACTACAAT TCCCAGAA GGAACTGCGA chr1:151227116-151227196 2 1.39e-05 C TCCCAGAA CGCAACGTGG chr17:7358815-7358895 10 1.39e-05 AACTACAGT TCCCAGAA GAGTGTGCGG chr19:49479585-49479665 17 1.39e-05 GAACTCTAAC TCCCAGAA GCCTCTGGAC chr3:50397066-50397146 22 3.18e-05 GAACTACAAG TCCCAGGA GGCCATGAGC chr17:40714336-40714416 46 3.18e-05 AGTTTCCCCC TCCCAGGA TTTCGACTCA chr19:44439447-44439527 17 4.89e-05 GAACTACATT TCCCAGCA TCCCCGGGAG chr19:9251000-9251080 1 4.89e-05 . tcccagca tcctctccgc chr1:22755259-22755339 27 4.89e-05 agactacatt tcccagca taccttgcag chr11:46134682-46134762 13 4.89e-05 CAACTACAGG TCCCAGCA TGCAGTGCTC chr19:4815782-4815862 47 6.03e-05 gtctatgccc tccaagaa gAGGCGTGCA chr7:100861306-100861386 31 8.57e-05 CTTTCTTGTC TCCAAGGA AACGCCACGT chr19:44711545-44711625 18 8.57e-05 GTATTTCCGC TCCAAGGA GCGGAACTAT chr20:36007742-36007822 6 8.57e-05 CCCTC TCCAAGGA GCAACTCATG chr14:77924102-77924182 58 9.96e-05 AGACTACAAT TCCCATGA GGCTCAGCAA chr19:41084561-41084641 58 9.96e-05 ACACAGCATT TCCCATGA GACAATGGGC chr1:142891053-142891133 52 9.96e-05 ACACTACAAT TCCCATGA GACTTTGCGG chr17:79212919-79212999 64 1.59e-04 CAATCCGAAG TCCCAGAG CACAGACAG chr6:33257266-33257346 42 1.59e-04 GAACTACACT TCCCATCA AGGGTCAGAA chr16:30759395-30759475 50 1.59e-04 AGATCACGTT TCCCAGTA AACCCAACTT chr12:88535935-88536015 58 1.59e-04 GGACTTCAAA TCCCAGAG TGCAGTTCTG chr14:73493969-73494049 29 1.59e-04 TGACTACAAC TCCCAGTA CTGAAGAGGC chr17:38375418-38375498 72 1.90e-04 GGGGCGGGCT TCCCAGGG G chr16:57769286-57769366 2 1.90e-04 T TCCAATAA TGCGGACGCT chr19:58144451-58144531 29 2.02e-04 AGTACTTTGA TCCAATGA AAATCCAAGA chr16:25122889-25122969 66 2.02e-04 AAAATAATTA TCCAATGA GCAACTT chr15:91565805-91565885 46 2.24e-04 TCCCTTTCGC TCCCAGCG CTTCGCGTAC chr1:243418779-243418859 17 2.24e-04 GGACTACAGT TCCCAGCG GGCAGAGCGC chr19:4540251-4540331 42 2.61e-04 TTGGGGGGCA TCCAAGAG TCTCTCTAGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCAGVA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:3185476-3185556 1.4e-05 53_[+5]_19 chr19:51963859-51963939 1.4e-05 7_[+5]_65 chr8:82754996-82755076 1.4e-05 38_[+5]_34 chr1:151227116-151227196 1.4e-05 1_[+5]_71 chr17:7358815-7358895 1.4e-05 9_[+5]_63 chr19:49479585-49479665 1.4e-05 16_[+5]_56 chr3:50397066-50397146 3.2e-05 21_[+5]_51 chr17:40714336-40714416 3.2e-05 45_[+5]_27 chr19:44439447-44439527 4.9e-05 16_[+5]_56 chr19:9251000-9251080 4.9e-05 [+5]_72 chr1:22755259-22755339 4.9e-05 26_[+5]_46 chr11:46134682-46134762 4.9e-05 12_[+5]_60 chr19:4815782-4815862 6e-05 46_[+5]_26 chr7:100861306-100861386 8.6e-05 30_[+5]_42 chr19:44711545-44711625 8.6e-05 17_[+5]_55 chr20:36007742-36007822 8.6e-05 5_[+5]_67 chr14:77924102-77924182 0.0001 57_[+5]_15 chr19:41084561-41084641 0.0001 57_[+5]_15 chr1:142891053-142891133 0.0001 51_[+5]_21 chr17:79212919-79212999 0.00016 63_[+5]_9 chr6:33257266-33257346 0.00016 41_[+5]_31 chr16:30759395-30759475 0.00016 49_[+5]_23 chr12:88535935-88536015 0.00016 57_[+5]_15 chr14:73493969-73494049 0.00016 28_[+5]_44 chr17:38375418-38375498 0.00019 71_[+5]_1 chr16:57769286-57769366 0.00019 1_[+5]_71 chr19:58144451-58144531 0.0002 28_[+5]_44 chr16:25122889-25122969 0.0002 65_[+5]_7 chr15:91565805-91565885 0.00022 45_[+5]_27 chr1:243418779-243418859 0.00022 16_[+5]_56 chr19:4540251-4540331 0.00026 41_[+5]_31 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCAGVA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCCCAGVA width=8 seqs=31 chr19:3185476-3185556 ( 54) TCCCAGAA 1 chr19:51963859-51963939 ( 8) TCCCAGAA 1 chr8:82754996-82755076 ( 39) TCCCAGAA 1 chr1:151227116-151227196 ( 2) TCCCAGAA 1 chr17:7358815-7358895 ( 10) TCCCAGAA 1 chr19:49479585-49479665 ( 17) TCCCAGAA 1 chr3:50397066-50397146 ( 22) TCCCAGGA 1 chr17:40714336-40714416 ( 46) TCCCAGGA 1 chr19:44439447-44439527 ( 17) TCCCAGCA 1 chr19:9251000-9251080 ( 1) TCCCAGCA 1 chr1:22755259-22755339 ( 27) TCCCAGCA 1 chr11:46134682-46134762 ( 13) TCCCAGCA 1 chr19:4815782-4815862 ( 47) TCCAAGAA 1 chr7:100861306-100861386 ( 31) TCCAAGGA 1 chr19:44711545-44711625 ( 18) TCCAAGGA 1 chr20:36007742-36007822 ( 6) TCCAAGGA 1 chr14:77924102-77924182 ( 58) TCCCATGA 1 chr19:41084561-41084641 ( 58) TCCCATGA 1 chr1:142891053-142891133 ( 52) TCCCATGA 1 chr17:79212919-79212999 ( 64) TCCCAGAG 1 chr6:33257266-33257346 ( 42) TCCCATCA 1 chr16:30759395-30759475 ( 50) TCCCAGTA 1 chr12:88535935-88536015 ( 58) TCCCAGAG 1 chr14:73493969-73494049 ( 29) TCCCAGTA 1 chr17:38375418-38375498 ( 72) TCCCAGGG 1 chr16:57769286-57769366 ( 2) TCCAATAA 1 chr19:58144451-58144531 ( 29) TCCAATGA 1 chr16:25122889-25122969 ( 66) TCCAATGA 1 chr15:91565805-91565885 ( 46) TCCCAGCG 1 chr1:243418779-243418859 ( 17) TCCCAGCG 1 chr19:4540251-4540331 ( 42) TCCAAGAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCAGVA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.4993 E= 2.4e+002 -1160 -1160 -1160 217 -1160 188 -1160 -1160 -1160 188 -1160 -1160 22 145 -1160 -1160 217 -1160 -1160 -1160 -1160 -1160 144 3 68 -27 32 -178 186 -1160 -56 -1160 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCAGVA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 31 E= 2.4e+002 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.258065 0.741935 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.774194 0.225806 0.354839 0.225806 0.354839 0.064516 0.806452 0.000000 0.193548 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCCAGVA MEME-5 regular expression -------------------------------------------------------------------------------- TCC[CA]A[GT][AGC]A -------------------------------------------------------------------------------- Time 18.66 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:13815630-13815710 4.27e-02 80 chrX:2548924-2549004 1.07e-03 16_[+3(9.72e-06)]_1_[+1(3.18e-05)]_\ 47 chr7:130692410-130692490 3.46e-05 35_[+1(1.79e-05)]_37 chr22:22242758-22242838 1.27e-01 80 chr19:53445744-53445824 2.98e-01 80 chr6:150188560-150188640 1.71e-01 42_[+1(3.18e-05)]_30 chrX:2547888-2547968 1.98e-03 12_[+1(3.18e-05)]_12_[+3(9.72e-06)]_\ 29_[+1(3.18e-05)]_3 chr10:73083301-73083381 1.06e-02 [+1(3.18e-05)]_72 chr19:53228946-53229026 1.63e-02 61_[+1(1.79e-05)]_11 chr8:120845289-120845369 8.47e-01 80 chr19:49479585-49479665 1.73e-03 16_[+5(1.39e-05)]_56 chr10:62074241-62074321 2.25e-03 80 chr8:66556122-66556202 1.02e-01 80 chr11:46134682-46134762 2.35e-04 2_[+4(6.59e-05)]_2_[+5(4.89e-05)]_\ 60 chr4:174089349-174089429 5.92e-02 23_[+1(3.18e-05)]_4_[+1(8.97e-05)]_\ 37 chr10:25755019-25755099 5.14e-02 80 chr2:241500609-241500689 7.22e-02 35_[+1(1.79e-05)]_37 chr20:45810082-45810162 7.66e-03 21_[+1(3.18e-05)]_51 chr17:1227614-1227694 3.36e-01 [+1(5.48e-05)]_14_[+1(5.48e-05)]_21_\ [+1(5.48e-05)]_21 chr20:2489731-2489811 1.42e-03 40_[+4(4.62e-05)]_32 chr22:50201801-50201881 1.66e-02 20_[+1(1.79e-05)]_52 chr10:104503393-10450347 1.67e-01 80 chr1:142891053-142891133 7.76e-03 51_[+5(9.96e-05)]_21 chr2:133104958-133105038 1.18e-01 29_[+1(7.18e-05)]_43 chr7:64467030-64467110 4.68e-03 [+4(4.62e-05)]_43_[+2(9.12e-05)]_21 chr19:46498421-46498501 2.89e-02 13_[+1(1.79e-05)]_59 chr19:41082708-41082788 4.50e-02 58_[+2(1.87e-05)]_14 chr12:54582872-54582952 2.01e-04 48_[+3(9.72e-06)]_24 chrX:69353709-69353789 4.70e-02 80 chr5:82373371-82373451 1.69e-02 41_[+2(1.87e-05)]_21_[+2(1.87e-05)]_\ 2 chr17:7358815-7358895 8.95e-03 9_[+5(1.39e-05)]_63 chr19:55663509-55663589 2.20e-01 6_[+1(3.18e-05)]_33_[+1(3.18e-05)]_\ 12_[+1(3.18e-05)]_5 chr19:53073585-53073665 3.14e-01 80 chr1:12142006-12142086 2.58e-01 5_[+1(3.18e-05)]_18_[+1(3.18e-05)]_\ 18_[+1(3.18e-05)]_15 chr20:2083107-2083187 4.97e-01 80 chrX:2550381-2550461 1.41e-03 27_[+3(9.72e-06)]_1_[+1(3.18e-05)]_\ 20_[+1(3.18e-05)]_8 chr19:19475817-19475897 7.57e-03 60_[+1(8.97e-05)]_12 chr9:132346516-132346596 1.17e-02 65_[+1(3.18e-05)]_7 chr15:36871687-36871767 1.93e-02 52_[+1(3.18e-05)]_20 chr17:48075811-48075891 1.49e-02 11_[+2(1.87e-05)]_61 chr12:131239146-13123922 1.55e-02 10_[+2(3.40e-05)]_7_[+2(3.40e-05)]_\ 25_[+2(3.40e-05)]_14 chr1:154359179-154359259 3.85e-01 80 chr19:53238235-53238315 3.12e-02 50_[+1(5.48e-05)]_22 chr19:44716566-44716646 1.85e-02 80 chr17:61904502-61904582 6.09e-01 80 chr20:33735143-33735223 1.28e-03 45_[+1(1.79e-05)]_27 chr8:18067587-18067667 9.77e-02 80 chr19:53837001-53837081 1.04e-01 4_[+2(9.12e-05)]_68 chr3:129118415-129118495 5.24e-01 80 chr9:97021546-97021626 2.18e-02 47_[+1(7.18e-05)]_25 chr19:10028079-10028159 1.22e-04 3_[+4(3.48e-05)]_24_[+1(8.97e-05)]_\ 37 chr1:206736422-206736502 1.54e-02 39_[+2(4.86e-05)]_33 chr19:4815782-4815862 2.31e-03 46_[+5(6.03e-05)]_16_[+1(8.97e-05)]_\ 2 chr7:38948757-38948837 9.70e-04 45_[+2(4.86e-05)]_27 chr19:53289954-53290034 2.15e-02 62_[+1(5.48e-05)]_10 chr11:75186587-75186667 7.45e-02 61_[+2(3.40e-05)]_11 chr22:23096160-23096240 2.03e-02 15_[+2(1.87e-05)]_57 chr16:77225000-77225080 2.13e-03 24_[+2(1.87e-05)]_21_[+2(1.87e-05)]_\ 19 chr4:2470741-2470821 2.43e-02 28_[+2(9.12e-05)]_44 chr1:231473691-231473771 6.47e-02 37_[+2(9.12e-05)]_35 chr1:22755259-22755339 5.31e-05 2_[+1(5.48e-05)]_6_[+4(4.62e-05)]_2_\ [+5(4.89e-05)]_46 chr5:151151060-151151140 8.55e-02 80 chr6:37786708-37786788 1.49e-02 71_[+1(7.18e-05)]_1 chr19:19496520-19496600 2.13e-02 65_[+2(1.87e-05)]_7 chr19:41084561-41084641 5.45e-03 57_[+5(9.96e-05)]_15 chr12:108908906-10890898 8.35e-03 51_[+2(4.86e-05)]_21 chr19:21203412-21203492 3.91e-02 26_[+1(5.48e-05)]_46 chr19:16296086-16296166 8.81e-03 18_[+2(1.87e-05)]_54 chr12:108955121-10895520 4.94e-02 68_[+2(3.40e-05)]_4 chr15:37392534-37392614 6.52e-01 80 chr5:93447354-93447434 2.07e-01 80 chr19:53898414-53898494 4.46e-01 80 chr17:73452576-73452656 1.81e-01 80 chr20:18268884-18268964 4.95e-02 18_[+3(3.19e-05)]_54 chr19:58326307-58326387 2.66e-01 80 chr16:31724509-31724589 1.56e-02 49_[+1(5.48e-05)]_23 chr15:66874475-66874555 3.79e-01 80 chr13:114103569-11410364 5.52e-01 80 chr3:93781831-93781911 3.57e-04 6_[+3(1.94e-05)]_36_[+2(1.87e-05)]_\ 22 chr1:113162850-113162930 4.72e-01 80 chr8:21776016-21776096 1.24e-02 80 chr10:114206819-11420689 3.99e-01 80 chr6:88182463-88182543 4.79e-01 80 chr19:21950341-21950421 6.80e-02 50_[+2(9.12e-05)]_22 chr10:16859675-16859755 4.08e-02 49_[+2(9.12e-05)]_23 chr4:140149020-140149100 6.04e-03 51_[+2(9.12e-05)]_21 chr12:66524479-66524559 6.12e-03 42_[+2(1.87e-05)]_30 chr19:58331032-58331112 6.92e-03 49_[+1(1.79e-05)]_23 chr17:80163928-80164008 1.38e-02 23_[+1(5.48e-05)]_49 chr2:131129522-131129602 1.09e-01 18_[+1(7.18e-05)]_54 chr1:155211036-155211116 1.37e-03 54_[+2(3.40e-05)]_18 chr2:88927163-88927243 6.03e-02 80 chr12:6798752-6798832 5.60e-02 80 chrX:134975765-134975845 9.64e-02 80 chr19:58361133-58361213 3.03e-02 80 chr7:153111148-153111228 6.43e-02 21_[+2(4.86e-05)]_51 chrX:2549132-2549212 1.57e-04 4_[+3(9.72e-06)]_1_[+1(3.18e-05)]_\ 18_[+1(3.18e-05)]_20_[+1(3.18e-05)]_5 chr14:73493969-73494049 6.46e-04 80 chr16:57769286-57769366 9.65e-02 80 chr15:64648491-64648571 4.00e-03 29_[+2(9.12e-05)]_43 chr20:36007742-36007822 1.74e-03 5_[+5(8.57e-05)]_36_[+2(3.40e-05)]_\ 23 chr17:40714336-40714416 3.66e-02 45_[+5(3.18e-05)]_27 chr10:15902534-15902614 9.08e-04 24_[+2(1.87e-05)]_7_[+2(1.87e-05)]_\ 2_[+3(9.58e-05)]_23 chr1:222763258-222763338 1.71e-03 9_[+2(1.87e-05)]_17_[+2(3.40e-05)]_\ 38 chr12:88535935-88536015 9.94e-03 80 chr16:30759395-30759475 4.18e-03 63_[+1(1.79e-05)]_9 chr11:22647367-22647447 1.75e-01 7_[+1(7.18e-05)]_65 chr6:160211426-160211506 1.72e-01 45_[+1(1.79e-05)]_27 chr11:69197235-69197315 3.93e-02 47_[+2(1.87e-05)]_25 chr19:58892658-58892738 2.33e-01 80 chr1:38388648-38388728 1.69e-02 80 chr7:111846540-111846620 7.08e-05 12_[+3(9.72e-06)]_17_[+2(1.87e-05)]_\ 35 chrX:130037298-130037378 1.33e-01 80 chr12:56223382-56223462 3.86e-03 37_[+1(1.79e-05)]_35 chrX:70585742-70585822 2.70e-02 19_[+1(1.79e-05)]_53 chr8:120845082-120845162 3.52e-02 13_[+2(9.12e-05)]_22_[+2(3.40e-05)]_\ 29 chr19:44669113-44669193 5.79e-05 52_[+1(1.79e-05)]_20 chr5:130971248-130971328 1.60e-02 61_[+2(9.12e-05)]_11 chr8:30601703-30601783 7.12e-01 80 chr19:44617461-44617541 3.10e-03 15_[+3(3.19e-05)]_57 chr3:50397066-50397146 3.15e-04 11_[+4(1.14e-05)]_2_[+5(3.18e-05)]_\ 51 chr20:10415819-10415899 9.46e-01 80 chr19:9251000-9251080 2.07e-03 [+5(4.89e-05)]_72 chr1:160991249-160991329 4.24e-02 80 chr9:135282169-135282249 2.27e-02 38_[+2(1.87e-05)]_15_[+2(9.12e-05)]_\ 11 chr6:3209665-3209745 4.53e-02 80 chr1:243418779-243418859 2.15e-04 6_[+4(3.48e-05)]_27_[+3(5.41e-05)]_\ 31 chr19:44711545-44711625 1.76e-05 17_[+5(8.57e-05)]_37_[+3(3.19e-05)]_\ 10 chr14:77924102-77924182 1.15e-03 47_[+4(4.62e-05)]_2_[+5(9.96e-05)]_\ 15 chr19:6604106-6604186 1.99e-03 6_[+3(5.41e-05)]_66 chr18:61089720-61089800 5.52e-01 80 chr17:4634684-4634764 2.90e-02 38_[+1(1.79e-05)]_34 chr19:21512135-21512215 1.93e-01 38_[+2(9.12e-05)]_34 chrX:153775809-153775889 5.90e-02 23_[+2(9.12e-05)]_49 chr12:21654546-21654626 3.32e-01 80 chr13:41837711-41837791 6.40e-02 5_[+1(3.18e-05)]_67 chr1:36335198-36335278 1.65e-04 11_[+3(9.58e-05)]_29_[+1(1.79e-05)]_\ 24 chr5:93447555-93447635 2.73e-02 80 chr6:147523590-147523670 5.22e-04 36_[+4(3.48e-05)]_36 chr16:25122889-25122969 3.94e-02 80 chr4:41937132-41937212 2.79e-03 21_[+1(1.79e-05)]_51 chr9:102861346-102861426 3.90e-04 6_[+3(5.41e-05)]_66 chr5:85913621-85913701 6.09e-03 7_[+4(3.48e-05)]_44_[+4(1.14e-05)]_\ 13 chr16:15150041-15150121 1.34e-03 15_[+2(3.40e-05)]_48_[+3(3.19e-05)]_\ 1 chr19:53141494-53141574 2.26e-01 50_[+3(9.58e-05)]_22 chr11:60681347-60681427 5.32e-04 7_[+4(1.14e-05)]_65 chr17:80408759-80408839 7.98e-02 80 chr7:150725390-150725470 1.57e-02 80 chr1:151227116-151227196 1.02e-02 1_[+5(1.39e-05)]_71 chr16:4524664-4524744 2.17e-01 80 chr7:72298921-72299001 1.65e-01 80 chr12:46780166-46780246 1.32e-01 80 chr22:24372885-24372965 1.30e-04 51_[+2(4.86e-05)]_21 chr19:44439447-44439527 1.11e-05 6_[+4(1.14e-05)]_2_[+5(4.89e-05)]_\ 38_[+2(9.12e-05)]_10 chr15:50716283-50716363 2.54e-03 52_[+2(4.86e-05)]_20 chr1:203595772-203595852 4.16e-03 41_[+2(3.40e-05)]_31 chr7:128546845-128546925 4.15e-01 80 chr19:46234182-46234262 1.42e-04 21_[+3(1.94e-05)]_13_[+4(3.48e-05)]_\ 30 chr8:82754996-82755076 3.76e-04 28_[+4(4.62e-05)]_2_[+5(1.39e-05)]_\ 34 chr11:109817122-10981720 6.18e-02 80 chr2:55459535-55459615 6.35e-01 80 chr16:30583338-30583418 2.50e-02 80 chr6:24721486-24721566 2.63e-01 80 chr16:30621736-30621816 5.20e-01 80 chr4:56719779-56719859 2.17e-03 22_[+1(1.79e-05)]_50 chr10:32218421-32218501 6.77e-02 28_[+2(1.87e-05)]_44 chr19:58427981-58428061 5.88e-01 80 chr9:104296049-104296129 3.02e-01 80 chr5:55008107-55008187 1.07e-01 80 chr19:44507037-44507117 2.79e-03 62_[+1(1.79e-05)]_10 chr1:42922544-42922624 6.30e-02 63_[+1(1.79e-05)]_9 chr15:91565805-91565885 7.82e-05 28_[+2(1.87e-05)]_44 chr1:23694875-23694955 5.43e-01 80 chr11:94801860-94801940 9.86e-02 30_[+1(8.97e-05)]_42 chrX:48432666-48432746 6.05e-03 80 chr19:4540251-4540331 4.34e-02 19_[+1(8.97e-05)]_53 chr16:19535074-19535154 1.56e-01 80 chr17:34957975-34958055 2.19e-01 40_[+2(9.12e-05)]_32 chr19:53606602-53606682 2.07e-02 61_[+1(1.79e-05)]_11 chr19:46366545-46366625 3.92e-03 31_[+3(5.41e-05)]_41 chr11:62521447-62521527 5.60e-02 80 chr2:66662211-66662291 1.87e-02 29_[+1(1.79e-05)]_43 chr1:32355149-32355229 1.68e-01 72_[+1(3.18e-05)] chr2:133105157-133105237 7.42e-01 80 chr2:202097041-202097121 8.36e-03 80 chr19:56826375-56826455 5.51e-01 80 chr4:37003425-37003505 2.14e-01 80 chr12:50505684-50505764 3.23e-02 68_[+2(9.12e-05)]_4 chr19:18133041-18133121 2.37e-03 22_[+1(3.18e-05)]_33_[+3(9.58e-05)]_\ 9 chr19:7616378-7616458 6.44e-02 80 chr19:58144451-58144531 1.50e-02 80 chr2:180871960-180872040 1.06e-03 69_[+4(1.14e-05)]_3 chr3:50388393-50388473 9.17e-01 80 chr17:47492356-47492436 6.03e-03 11_[+4(1.14e-05)]_61 chr17:73780711-73780791 4.31e-01 80 chr1:33116122-33116202 6.84e-02 29_[+1(7.18e-05)]_33_[+1(7.18e-05)]_\ 2 chr15:78832677-78832757 9.47e-02 40_[+1(7.18e-05)]_32 chr16:28503412-28503492 8.91e-02 29_[+1(1.79e-05)]_43 chr7:64363614-64363694 1.13e-01 11_[+1(5.48e-05)]_61 chr17:38375418-38375498 3.87e-02 80 chr2:32502801-32502881 8.47e-05 60_[+1(3.18e-05)]_12 chr6:8064746-8064826 3.14e-01 80 chr15:91473396-91473476 1.36e-01 80 chr9:130700152-130700232 5.07e-02 80 chr6:33257266-33257346 2.03e-05 31_[+4(1.14e-05)]_24_[+1(1.79e-05)]_\ 9 chr16:84457296-84457376 5.06e-02 18_[+2(3.40e-05)]_54 chr6:30484247-30484327 1.94e-01 80 chr2:201676445-201676525 2.29e-01 80 chr10:121356539-12135661 1.59e-03 47_[+2(3.40e-05)]_25 chr6:33151081-33151161 3.27e-03 20_[+2(3.40e-05)]_52 chr16:30366627-30366707 3.98e-02 20_[+2(1.87e-05)]_37_[+2(9.12e-05)]_\ 7 chr8:18067812-18067892 8.50e-01 80 chr11:66247883-66247963 1.38e-01 17_[+2(3.40e-05)]_55 chr1:213189206-213189286 2.67e-01 80 chr19:52598942-52599022 3.66e-02 64_[+1(5.48e-05)]_8 chr4:140004101-140004181 3.00e-01 80 chr19:3990357-3990437 7.63e-02 71_[+3(5.41e-05)]_1 chr1:95538380-95538460 1.14e-01 80 chr19:51963859-51963939 1.26e-04 7_[+5(1.39e-05)]_15_[+1(8.97e-05)]_\ 42 chr19:54663684-54663764 1.44e-01 80 chr19:14192197-14192277 4.28e-01 80 chr8:102166127-102166207 6.74e-04 67_[+2(3.40e-05)]_5 chr1:47780138-47780218 2.14e-02 20_[+2(1.87e-05)]_52 chr19:3185476-3185556 3.77e-04 43_[+4(3.48e-05)]_2_[+5(1.39e-05)]_\ 19 chr15:41099664-41099744 2.01e-02 [+4(9.12e-05)]_72 chr22:20207353-20207433 3.74e-03 21_[+1(3.18e-05)]_51 chr3:4781622-4781702 1.10e-02 40_[+2(3.40e-05)]_32 chr2:178417572-178417652 6.74e-01 80 chr11:57434987-57435067 1.68e-01 80 chrX:950792-950872 1.59e-02 80 chr11:71639559-71639639 7.82e-03 80 chr18:55297496-55297576 2.27e-01 37_[+1(7.18e-05)]_35 chr16:57219931-57220011 6.04e-02 33_[+1(1.79e-05)]_39 chr17:12921504-12921584 4.35e-04 27_[+2(9.12e-05)]_20_[+1(1.79e-05)]_\ 17 chr2:85822684-85822764 9.05e-02 50_[+1(7.18e-05)]_22 chr10:131909480-13190956 1.80e-01 66_[+1(5.48e-05)]_6 chr17:73975672-73975752 1.45e-01 13_[+1(5.48e-05)]_59 chr7:100861306-100861386 2.49e-02 30_[+5(8.57e-05)]_42 chr11:107436329-10743640 7.07e-01 80 chr22:27068806-27068886 1.09e-02 50_[+2(1.87e-05)]_22 chr17:79212919-79212999 1.26e-02 38_[+3(9.58e-05)]_34 chr19:36239283-36239363 1.65e-06 3_[+4(1.14e-05)]_2_[+5(3.18e-05)]_\ 24_[+2(9.12e-05)]_27 chrX:71792838-71792918 5.86e-01 80 chr17:8093570-8093650 1.59e-02 38_[+2(3.40e-05)]_34 chr17:73390051-73390131 1.34e-01 80 chr20:44486063-44486143 4.11e-01 80 chr19:12780368-12780448 7.51e-02 80 chrX:155110888-155110968 4.50e-01 80 chr11:45939440-45939520 1.55e-02 [+1(5.48e-05)]_26_[+1(7.18e-05)]_38 chr14:21924335-21924415 5.94e-03 64_[+2(3.40e-05)]_8 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n04.farnam.hpc.yale.internal ********************************************************************************