******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/DNMT1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr17:100243-100323 1.0000 80 chrX:69657917-69657997 1.0000 80 chr11:70694609-70694689 1.0000 80 chr16:20752451-20752531 1.0000 80 chr3:37000765-37000845 1.0000 80 chr1:25278872-25278952 1.0000 80 chr10:134367162-13436724 1.0000 80 chr14:103811707-10381178 1.0000 80 chr2:113770163-113770243 1.0000 80 chr1:235369963-235370043 1.0000 80 chr19:50886994-50887074 1.0000 80 chr9:94670230-94670310 1.0000 80 chr1:184724547-184724627 1.0000 80 chr1:36714397-36714477 1.0000 80 chr6:149866723-149866803 1.0000 80 chr1:179199821-179199901 1.0000 80 chr7:127031600-127031680 1.0000 80 chr22:19390297-19390377 1.0000 80 chr6:31644433-31644513 1.0000 80 chr6:168226731-168226811 1.0000 80 chr12:46751881-46751961 1.0000 80 chr6:4794683-4794763 1.0000 80 chr10:74452891-74452971 1.0000 80 chr2:71222308-71222388 1.0000 80 chr1:150534328-150534408 1.0000 80 chr19:4470501-4470581 1.0000 80 chr1:23806046-23806126 1.0000 80 chr19:7991232-7991312 1.0000 80 chr19:7713575-7713655 1.0000 80 chr22:20823468-20823548 1.0000 80 chr7:120629134-120629214 1.0000 80 chr6:13662587-13662667 1.0000 80 chr20:50053933-50054013 1.0000 80 chr1:44115266-44115346 1.0000 80 chr12:112554771-11255485 1.0000 80 chr7:14032029-14032109 1.0000 80 chr17:56066118-56066198 1.0000 80 chr7:75508817-75508897 1.0000 80 chr12:57909914-57909994 1.0000 80 chr6:44424228-44424308 1.0000 80 chr22:19159756-19159836 1.0000 80 chr3:39449763-39449843 1.0000 80 chr1:246377667-246377747 1.0000 80 chr1:11864496-11864576 1.0000 80 chr22:22849755-22849835 1.0000 80 chr1:70876362-70876442 1.0000 80 chr5:28812819-28812899 1.0000 80 chr16:14013373-14013453 1.0000 80 chr15:32933869-32933949 1.0000 80 chr7:76009813-76009893 1.0000 80 chr10:29111457-29111537 1.0000 80 chr1:167833737-167833817 1.0000 80 chr7:138794938-138795018 1.0000 80 chr16:85085044-85085124 1.0000 80 chr6:28740146-28740226 1.0000 80 chr10:75716941-75717021 1.0000 80 chr16:3071672-3071752 1.0000 80 chr15:96226883-96226963 1.0000 80 chr22:21450136-21450216 1.0000 80 chr2:158649867-158649947 1.0000 80 chr11:9635440-9635520 1.0000 80 chr2:70201826-70201906 1.0000 80 chr6:28832382-28832462 1.0000 80 chr6:168227215-168227295 1.0000 80 chr19:45928106-45928186 1.0000 80 chr6:150188876-150188956 1.0000 80 chr3:38207881-38207961 1.0000 80 chr6:108887208-108887288 1.0000 80 chr6:40995511-40995591 1.0000 80 chr7:16779577-16779657 1.0000 80 chr8:20061504-20061584 1.0000 80 chr1:167192737-167192817 1.0000 80 chr5:131842157-131842237 1.0000 80 chr1:51985779-51985859 1.0000 80 chr1:205781072-205781152 1.0000 80 chr11:59384227-59384307 1.0000 80 chr2:105945037-105945117 1.0000 80 chr6:32163047-32163127 1.0000 80 chr3:40409971-40410051 1.0000 80 chr7:86777716-86777796 1.0000 80 chr6:34302759-34302839 1.0000 80 chr7:106649390-106649470 1.0000 80 chr20:62496009-62496089 1.0000 80 chr21:38452124-38452204 1.0000 80 chr12:58148435-58148515 1.0000 80 chr1:27867980-27868060 1.0000 80 chr11:74171671-74171751 1.0000 80 chr6:111927541-111927621 1.0000 80 chr2:70335038-70335118 1.0000 80 chr6:138184923-138185003 1.0000 80 chr20:44993422-44993502 1.0000 80 chr3:9772645-9772725 1.0000 80 chr18:9008729-9008809 1.0000 80 chr6:134516254-134516334 1.0000 80 chr1:32422145-32422225 1.0000 80 chr1:7830994-7831074 1.0000 80 chr5:162888555-162888635 1.0000 80 chr9:130913027-130913107 1.0000 80 chr1:1550298-1550378 1.0000 80 chr5:154215148-154215228 1.0000 80 chr14:23540635-23540715 1.0000 80 chr1:167189121-167189201 1.0000 80 chr6:26595537-26595617 1.0000 80 chr22:18155575-18155655 1.0000 80 chr3:151960602-151960682 1.0000 80 chr19:17208536-17208616 1.0000 80 chr19:46296631-46296711 1.0000 80 chr12:58139139-58139219 1.0000 80 chr1:179850146-179850226 1.0000 80 chr4:39640985-39641065 1.0000 80 chr15:64182983-64183063 1.0000 80 chr17:45144390-45144470 1.0000 80 chr1:110075461-110075541 1.0000 80 chr11:65487643-65487723 1.0000 80 chr4:100868265-100868345 1.0000 80 chr3:142298352-142298432 1.0000 80 chr18:9920005-9920085 1.0000 80 chr19:10946037-10946117 1.0000 80 chr12:49657974-49658054 1.0000 80 chr19:40969838-40969918 1.0000 80 chr6:16259635-16259715 1.0000 80 chr9:140446836-140446916 1.0000 80 chr19:13209317-13209397 1.0000 80 chr16:67694490-67694570 1.0000 80 chr1:197167657-197167737 1.0000 80 chr16:1701832-1701912 1.0000 80 chr17:45306910-45306990 1.0000 80 chr19:13264988-13265068 1.0000 80 chr22:17081652-17081732 1.0000 80 chr22:20047173-20047253 1.0000 80 chr6:37393967-37394047 1.0000 80 chr5:149085851-149085931 1.0000 80 chr22:19815023-19815103 1.0000 80 chr7:123173506-123173586 1.0000 80 chr4:75023298-75023378 1.0000 80 chr9:139683251-139683331 1.0000 80 chr11:116969621-11696970 1.0000 80 chr7:74070417-74070497 1.0000 80 chr2:183899176-183899256 1.0000 80 chr1:145443618-145443698 1.0000 80 chr11:64072409-64072489 1.0000 80 chr18:3625255-3625335 1.0000 80 chr19:19515482-19515562 1.0000 80 chr6:43594456-43594536 1.0000 80 chr1:248020060-248020140 1.0000 80 chrX:48660639-48660719 1.0000 80 chr22:19417897-19417977 1.0000 80 chr10:75126470-75126550 1.0000 80 chr6:31870504-31870584 1.0000 80 chr11:64084740-64084820 1.0000 80 chr4:48318170-48318250 1.0000 80 chr22:20098539-20098619 1.0000 80 chr16:285169-285249 1.0000 80 chr6:2846383-2846463 1.0000 80 chr1:114347150-114347230 1.0000 80 chr11:33963754-33963834 1.0000 80 chr6:33172533-33172613 1.0000 80 chr1:78470790-78470870 1.0000 80 chr17:44062878-44062958 1.0000 80 chr5:78429772-78429852 1.0000 80 chr19:45996235-45996315 1.0000 80 chr7:156741973-156742053 1.0000 80 chr12:53399538-53399618 1.0000 80 chr7:99070786-99070866 1.0000 80 chr5:139126756-139126836 1.0000 80 chr11:18763495-18763575 1.0000 80 chr1:198127013-198127093 1.0000 80 chr20:60962610-60962690 1.0000 80 chr6:33385309-33385389 1.0000 80 chr1:113248058-113248138 1.0000 80 chr7:139305632-139305712 1.0000 80 chr1:161591152-161591232 1.0000 80 chr2:69878533-69878613 1.0000 80 chr11:20384885-20384965 1.0000 80 chr6:33217456-33217536 1.0000 80 chr3:37270990-37271070 1.0000 80 chr11:67764459-67764539 1.0000 80 chr1:179027952-179028032 1.0000 80 chr1:167895900-167895980 1.0000 80 chr21:40555689-40555769 1.0000 80 chr1:15116506-15116586 1.0000 80 chr7:137650540-137650620 1.0000 80 chr20:49308489-49308569 1.0000 80 chr15:52274116-52274196 1.0000 80 chr19:13394871-13394951 1.0000 80 chr22:22965836-22965916 1.0000 80 chr22:19023362-19023442 1.0000 80 chr1:28844339-28844419 1.0000 80 chr6:30293710-30293790 1.0000 80 chr1:46987632-46987712 1.0000 80 chr11:57226448-57226528 1.0000 80 chr1:207922875-207922955 1.0000 80 chr6:31619621-31619701 1.0000 80 chr1:150847172-150847252 1.0000 80 chr4:140005179-140005259 1.0000 80 chr6:37211453-37211533 1.0000 80 chr17:46986751-46986831 1.0000 80 chr1:16382473-16382553 1.0000 80 chr6:26337387-26337467 1.0000 80 chr1:19537256-19537336 1.0000 80 chr1:157015054-157015134 1.0000 80 chr19:50096975-50097055 1.0000 80 chr22:19815711-19815791 1.0000 80 chr3:23958080-23958160 1.0000 80 chr21:45431152-45431232 1.0000 80 chr6:17714466-17714546 1.0000 80 chr11:65382435-65382515 1.0000 80 chr7:100034566-100034646 1.0000 80 chr1:116916859-116916939 1.0000 80 chr17:47068249-47068329 1.0000 80 chr2:65292158-65292238 1.0000 80 chr1:174972590-174972670 1.0000 80 chr10:88963705-88963785 1.0000 80 chr5:40834984-40835064 1.0000 80 chr2:27303910-27303990 1.0000 80 chr19:1480554-1480634 1.0000 80 chr17:45267362-45267442 1.0000 80 chr22:20306994-20307074 1.0000 80 chr1:11797274-11797354 1.0000 80 chr3:47517768-47517848 1.0000 80 chr10:23384103-23384183 1.0000 80 chr6:42897591-42897671 1.0000 80 chr1:40838900-40838980 1.0000 80 chr1:19535819-19535899 1.0000 80 chr7:106142858-106142938 1.0000 80 chr7:110969426-110969506 1.0000 80 chr6:136610123-136610203 1.0000 80 chr11:58939299-58939379 1.0000 80 chr6:31628213-31628293 1.0000 80 chr2:15696226-15696306 1.0000 80 chr7:120718090-120718170 1.0000 80 chr6:125475809-125475889 1.0000 80 chr18:3038835-3038915 1.0000 80 chr22:22055919-22055999 1.0000 80 chr15:90685936-90686016 1.0000 80 chr22:19166878-19166958 1.0000 80 chr9:117160548-117160628 1.0000 80 chr6:31775039-31775119 1.0000 80 chr16:67515530-67515610 1.0000 80 chr6:32098590-32098670 1.0000 80 chr11:63449604-63449684 1.0000 80 chr10:76871672-76871752 1.0000 80 chr7:150779922-150780002 1.0000 80 chr12:52278128-52278208 1.0000 80 chr11:60673469-60673549 1.0000 80 chr5:108064493-108064573 1.0000 80 chr2:238832636-238832716 1.0000 80 chr10:75531543-75531623 1.0000 80 chr6:11921693-11921773 1.0000 80 chr6:16169163-16169243 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_DNMT1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/DNMT1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.275 C 0.236 G 0.239 T 0.251 Background letter frequencies (from file dataset with add-one prior applied): A 0.275 C 0.236 G 0.239 T 0.251 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF YCCWGCCY MEME-1 width = 8 sites = 56 llr = 435 E-value = 2.0e-009 ******************************************************************************** -------------------------------------------------------------------------------- Motif YCCWGCCY MEME-1 Description -------------------------------------------------------------------------------- Simplified A :::5:::: pos.-specific C 5aa:27a6 probability G ::::63:: matrix T 5::52::4 bits 2.1 ** * 1.9 ** * 1.7 ** * 1.5 ** * Relative 1.3 ** ** Entropy 1.0 *** *** (11.2 bits) 0.8 **** *** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCCTGCCC consensus C A G T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCCWGCCY MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:27303910-27303990 59 2.14e-05 CGCAGAGATT CCCTGCCC gtgtgtgtgt chr6:31619621-31619701 8 2.14e-05 CATTAAT CCCTGCCC CAATACCTAA chr3:9772645-9772725 50 2.14e-05 CCCTAATCGG TCCTGCCC TTTCCCCACA chr12:58148435-58148515 45 2.14e-05 TGAGTCCCAC CCCTGCCC ATGTACCTCC chr11:67764459-67764539 37 4.48e-05 GGTCTTGCCT CCCAGCCC AAGGCCCCAT chr6:40995511-40995591 53 4.48e-05 TTCTCGCTGC TCCAGCCC GCACTCAGCT chr16:3071672-3071752 38 4.48e-05 CCCTGGCCTG CCCAGCCC TGTCAGCACT chr19:7713575-7713655 7 4.48e-05 TCTCCT CCCAGCCC CACGGGGTTC chr7:100034566-100034646 10 6.76e-05 aagagattc tcctgcct cagcctcctg chr6:37211453-37211533 30 6.76e-05 caagcgattc tcctgcct cagcatccca chr7:156741973-156742053 25 6.76e-05 caagcgattc tcctgcct cagcctccga chr6:2846383-2846463 62 6.76e-05 caagcgattc tcctgcct cagcctcctg chr6:30293710-30293790 34 9.25e-05 CATACTCTTC CCCAGCCT CATCACCTCA chr19:45996235-45996315 58 9.25e-05 GCCCCCTAGC CCCAGCCT GCAGCGCTGC chr1:179850146-179850226 69 9.25e-05 gccactggac tccagcct gggt chr1:1550298-1550378 64 9.25e-05 gccattgcac tccagcct gggcgacag chr2:70335038-70335118 51 9.25e-05 gccactgccc tccagcct gggcgacaga chr20:62496009-62496089 71 9.25e-05 gccatggcac tccagcct gg chr16:14013373-14013453 42 9.25e-05 gccactgcac tccagcct gggcaacata chr19:7991232-7991312 14 9.25e-05 CTTCGGGCCC CCCAGCCT GCCCTGTGCC chr1:46987632-46987712 64 1.14e-04 TAGACTCAGT TCCTGGCC CTATATATA chr1:167895900-167895980 71 1.14e-04 GGTTAAGAAA TCCTGGCC TA chr5:131842157-131842237 66 1.14e-04 agtatgatct tcctggcc tatgata chr15:32933869-32933949 53 1.14e-04 GTTCGCCCGT TCCTGGCC TGACCCCCAC chr6:31870504-31870584 29 1.35e-04 ATCACACCCG CCCTCCCC TCCATTCTCA chr6:26595537-26595617 67 1.35e-04 TCCATCATGC CCCTCCCC TAGCTC chr7:138794938-138795018 59 1.35e-04 TCAGATCGGT TCCTCCCC GTAGAGATTG chr17:56066118-56066198 10 1.35e-04 TTTGGCATT TCCTCCCC GGCCGGCTAA chr7:106142858-106142938 31 1.81e-04 ggactgctcc cccaggcc atgagtatac chr5:40834984-40835064 17 1.81e-04 ATTCCCAAAC TCCTTCCC TCGGCTCCCA chr17:47068249-47068329 39 1.81e-04 CATCTCTGCA TCCTTCCC TTTCACTAGA chr1:113248058-113248138 16 1.81e-04 TCCTGAGTGG CCCTTCCC TTGCCTCCAG chr1:32422145-32422225 32 1.81e-04 AAAGACTTTT TCCAGGCC TTTCCTACTT chr6:28832382-28832462 48 1.81e-04 CAACCCCAGA TCCAGGCC TGGCCTTCCT chr10:75716941-75717021 21 1.81e-04 AGGAGCTGAG CCCAGGCC CAGGACACAG chr16:85085044-85085124 57 1.81e-04 ATCCCCATTC CCCTTCCC GCTTCCCTCA chr7:75508817-75508897 12 1.81e-04 CGAATTTGTT CCCTTCCC TGTCGCCACC chr1:44115266-44115346 13 1.81e-04 AGGGCAGCTT CCCTTCCc tgttcaggct chr19:50096975-50097055 9 2.28e-04 CTCCCCAA CCCACCCC AATTCTTTCC chr18:3625255-3625335 49 2.28e-04 TTTCTGTCCT CCCACCCC GTGAGAGGTT chr11:64072409-64072489 31 2.28e-04 GTCGGCTTCA CCCACCCC GAGTTCCGCA chr19:13209317-13209397 45 2.28e-04 ttctctgccc tccacccc cgtctcTGCA chr6:111927541-111927621 21 2.28e-04 atcgagacca tcctggct aacaaggtga chr6:28740146-28740226 27 2.28e-04 acctgaggtt ccctggct attcctctgt chr20:50053933-50054013 49 2.75e-04 accaatgaac ccctCCCT ACTTTTAAGC chr1:157015054-157015134 55 3.24e-04 CTCCTCCACA TCCAGGCT CCGAAATTTT chr20:49308489-49308569 36 3.24e-04 CATTGCACAC CCCTTCCT TCCGTCCTGG chr1:15116506-15116586 33 3.24e-04 actcttgttg cccaggct ggagtgcaat chr1:145443618-145443698 47 3.24e-04 tgctctgtct cccaggct ggagtgcagt chr5:149085851-149085931 39 3.24e-04 ctttccttct tccttcct tctttccttt chr5:154215148-154215228 33 3.24e-04 cgctctgtcg cccaggct ggagtgcagt chr10:29111457-29111537 7 3.24e-04 ACAGAG TCCTTCCT CTACGAACAA chr1:7830994-7831074 40 3.48e-04 ATGAATTGCC CCCACCCT CACTTATCCA chr7:76009813-76009893 25 3.48e-04 GCTTTGGAAT TCCACCCT TCAGGGTGCA chr4:48318170-48318250 55 4.19e-04 GAAAATCACC TCCTTGCC ACTAGATGGT chrX:69657917-69657997 3 5.14e-04 tc tccttgct gttccttgag -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCCWGCCY MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:27303910-27303990 2.1e-05 58_[+1]_14 chr6:31619621-31619701 2.1e-05 7_[+1]_65 chr3:9772645-9772725 2.1e-05 49_[+1]_23 chr12:58148435-58148515 2.1e-05 44_[+1]_28 chr11:67764459-67764539 4.5e-05 36_[+1]_36 chr6:40995511-40995591 4.5e-05 52_[+1]_20 chr16:3071672-3071752 4.5e-05 37_[+1]_35 chr19:7713575-7713655 4.5e-05 6_[+1]_66 chr7:100034566-100034646 6.8e-05 9_[+1]_63 chr6:37211453-37211533 6.8e-05 29_[+1]_43 chr7:156741973-156742053 6.8e-05 24_[+1]_48 chr6:2846383-2846463 6.8e-05 61_[+1]_11 chr6:30293710-30293790 9.2e-05 33_[+1]_39 chr19:45996235-45996315 9.2e-05 57_[+1]_15 chr1:179850146-179850226 9.2e-05 68_[+1]_4 chr1:1550298-1550378 9.2e-05 63_[+1]_9 chr2:70335038-70335118 9.2e-05 50_[+1]_22 chr20:62496009-62496089 9.2e-05 70_[+1]_2 chr16:14013373-14013453 9.2e-05 41_[+1]_31 chr19:7991232-7991312 9.2e-05 13_[+1]_59 chr1:46987632-46987712 0.00011 63_[+1]_9 chr1:167895900-167895980 0.00011 70_[+1]_2 chr5:131842157-131842237 0.00011 65_[+1]_7 chr15:32933869-32933949 0.00011 52_[+1]_20 chr6:31870504-31870584 0.00014 28_[+1]_44 chr6:26595537-26595617 0.00014 66_[+1]_6 chr7:138794938-138795018 0.00014 58_[+1]_14 chr17:56066118-56066198 0.00014 9_[+1]_63 chr7:106142858-106142938 0.00018 30_[+1]_42 chr5:40834984-40835064 0.00018 16_[+1]_56 chr17:47068249-47068329 0.00018 38_[+1]_34 chr1:113248058-113248138 0.00018 15_[+1]_57 chr1:32422145-32422225 0.00018 31_[+1]_41 chr6:28832382-28832462 0.00018 47_[+1]_25 chr10:75716941-75717021 0.00018 20_[+1]_52 chr16:85085044-85085124 0.00018 56_[+1]_16 chr7:75508817-75508897 0.00018 11_[+1]_61 chr1:44115266-44115346 0.00018 12_[+1]_60 chr19:50096975-50097055 0.00023 8_[+1]_64 chr18:3625255-3625335 0.00023 48_[+1]_24 chr11:64072409-64072489 0.00023 30_[+1]_42 chr19:13209317-13209397 0.00023 44_[+1]_28 chr6:111927541-111927621 0.00023 20_[+1]_52 chr6:28740146-28740226 0.00023 26_[+1]_46 chr20:50053933-50054013 0.00027 48_[+1]_24 chr1:157015054-157015134 0.00032 54_[+1]_18 chr20:49308489-49308569 0.00032 35_[+1]_37 chr1:15116506-15116586 0.00032 32_[+1]_40 chr1:145443618-145443698 0.00032 46_[+1]_26 chr5:149085851-149085931 0.00032 38_[+1]_34 chr5:154215148-154215228 0.00032 32_[+1]_40 chr10:29111457-29111537 0.00032 6_[+1]_66 chr1:7830994-7831074 0.00035 39_[+1]_33 chr7:76009813-76009893 0.00035 24_[+1]_48 chr4:48318170-48318250 0.00042 54_[+1]_18 chrX:69657917-69657997 0.00051 2_[+1]_70 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCCWGCCY MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YCCWGCCY width=8 seqs=56 chr2:27303910-27303990 ( 59) CCCTGCCC 1 chr6:31619621-31619701 ( 8) CCCTGCCC 1 chr3:9772645-9772725 ( 50) TCCTGCCC 1 chr12:58148435-58148515 ( 45) CCCTGCCC 1 chr11:67764459-67764539 ( 37) CCCAGCCC 1 chr6:40995511-40995591 ( 53) TCCAGCCC 1 chr16:3071672-3071752 ( 38) CCCAGCCC 1 chr19:7713575-7713655 ( 7) CCCAGCCC 1 chr7:100034566-100034646 ( 10) TCCTGCCT 1 chr6:37211453-37211533 ( 30) TCCTGCCT 1 chr7:156741973-156742053 ( 25) TCCTGCCT 1 chr6:2846383-2846463 ( 62) TCCTGCCT 1 chr6:30293710-30293790 ( 34) CCCAGCCT 1 chr19:45996235-45996315 ( 58) CCCAGCCT 1 chr1:179850146-179850226 ( 69) TCCAGCCT 1 chr1:1550298-1550378 ( 64) TCCAGCCT 1 chr2:70335038-70335118 ( 51) TCCAGCCT 1 chr20:62496009-62496089 ( 71) TCCAGCCT 1 chr16:14013373-14013453 ( 42) TCCAGCCT 1 chr19:7991232-7991312 ( 14) CCCAGCCT 1 chr1:46987632-46987712 ( 64) TCCTGGCC 1 chr1:167895900-167895980 ( 71) TCCTGGCC 1 chr5:131842157-131842237 ( 66) TCCTGGCC 1 chr15:32933869-32933949 ( 53) TCCTGGCC 1 chr6:31870504-31870584 ( 29) CCCTCCCC 1 chr6:26595537-26595617 ( 67) CCCTCCCC 1 chr7:138794938-138795018 ( 59) TCCTCCCC 1 chr17:56066118-56066198 ( 10) TCCTCCCC 1 chr7:106142858-106142938 ( 31) CCCAGGCC 1 chr5:40834984-40835064 ( 17) TCCTTCCC 1 chr17:47068249-47068329 ( 39) TCCTTCCC 1 chr1:113248058-113248138 ( 16) CCCTTCCC 1 chr1:32422145-32422225 ( 32) TCCAGGCC 1 chr6:28832382-28832462 ( 48) TCCAGGCC 1 chr10:75716941-75717021 ( 21) CCCAGGCC 1 chr16:85085044-85085124 ( 57) CCCTTCCC 1 chr7:75508817-75508897 ( 12) CCCTTCCC 1 chr1:44115266-44115346 ( 13) CCCTTCCC 1 chr19:50096975-50097055 ( 9) CCCACCCC 1 chr18:3625255-3625335 ( 49) CCCACCCC 1 chr11:64072409-64072489 ( 31) CCCACCCC 1 chr19:13209317-13209397 ( 45) TCCACCCC 1 chr6:111927541-111927621 ( 21) TCCTGGCT 1 chr6:28740146-28740226 ( 27) CCCTGGCT 1 chr20:50053933-50054013 ( 49) CCCTCCCT 1 chr1:157015054-157015134 ( 55) TCCAGGCT 1 chr20:49308489-49308569 ( 36) CCCTTCCT 1 chr1:15116506-15116586 ( 33) CCCAGGCT 1 chr1:145443618-145443698 ( 47) CCCAGGCT 1 chr5:149085851-149085931 ( 39) TCCTTCCT 1 chr5:154215148-154215228 ( 33) CCCAGGCT 1 chr10:29111457-29111537 ( 7) TCCTTCCT 1 chr1:7830994-7831074 ( 40) CCCACCCT 1 chr7:76009813-76009893 ( 25) TCCACCCT 1 chr4:48318170-48318250 ( 55) TCCTTGCC 1 chrX:69657917-69657997 ( 3) TCCTTGCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCCWGCCY MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.3065 E= 2.0e-009 -1245 103 -1245 105 -1245 209 -1245 -1245 -1245 209 -1245 -1245 75 -1245 -1245 110 -1245 -26 135 -35 -1245 160 26 -1245 -1245 209 -1245 -1245 -1245 123 -1245 83 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCCWGCCY MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 56 E= 2.0e-009 0.000000 0.482143 0.000000 0.517857 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.464286 0.000000 0.000000 0.535714 0.000000 0.196429 0.607143 0.196429 0.000000 0.714286 0.285714 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.553571 0.000000 0.446429 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YCCWGCCY MEME-1 regular expression -------------------------------------------------------------------------------- [TC]CC[TA]G[CG]C[CT] -------------------------------------------------------------------------------- Time 5.03 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTSTTTT MEME-2 width = 8 sites = 29 llr = 249 E-value = 1.2e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTSTTTT MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C :1:3221: probability G :::5:::: matrix T a9a2889a bits 2.1 * * * 1.9 * * * 1.7 *** ** 1.5 *** ** Relative 1.3 *** **** Entropy 1.0 *** **** (12.4 bits) 0.8 *** **** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTTGTTTT consensus CCC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTSTTTT MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:120718090-120718170 16 1.50e-05 TAttttttgt tttgtttt tgtttttgag chr11:20384885-20384965 59 1.50e-05 TAGGAATAGG TTTGTTTT ATTCCTGTTT chr19:13264988-13265068 40 1.50e-05 TGTTTGTTTG TTTGTTTT TAAAGATCTC chr17:45144390-45144470 64 1.50e-05 aaactgattt tttgtttt aaatgtggg chr5:154215148-154215228 1 1.50e-05 . tttgtttt ttgagacaga chr7:16779577-16779657 73 1.50e-05 gagattcctt tttgtttt chr5:28812819-28812899 38 1.50e-05 ATTTGAAATA TTTGTTTT GCCATGGTCT chr1:44115266-44115346 66 1.50e-05 gccacgggat tttgtttt gaaaacc chr2:69878533-69878613 2 2.98e-05 G TTTCTTTT GATTCTTACT chr19:45928106-45928186 71 2.98e-05 AAttcttttt tttctttt tt chr1:15116506-15116586 2 5.97e-05 t tttttttt gagacagagt chr6:37393967-37394047 44 5.97e-05 atcttaagac tttttttt aagtctttgt chr3:151960602-151960682 29 5.97e-05 aatttttgta tttttttt agtagagatg chr22:18155575-18155655 24 5.97e-05 ATTTTTGTCA TTTGCTTT GTGGGATGGT chr7:127031600-127031680 32 5.97e-05 CTCGACCTAC TTTGCTTT CACTGTAAGA chr1:179199821-179199901 52 5.97e-05 GGCTTCCCAA TTTGCTTT ATAAAAAGTA chr5:149085851-149085931 49 8.77e-05 tccttccttc tttccttt cttcccttct chr22:17081652-17081732 15 8.77e-05 TAGCCCCATT TTTCCTTT TACCATTTTT chr6:108887208-108887288 21 8.77e-05 CGTTTTGTAA TTTCCTTT GGCAATAGTG chr1:157015054-157015134 70 1.02e-04 GCTCCGAAAT TTTCTCTT GCC chr7:123173506-123173586 28 1.02e-04 TGATGTTGTT TTTCTCTT ACTATATAAA chr7:14032029-14032109 10 1.02e-04 TTCTCCCAC TTTCTCTT CTGTCCTTTC chr18:3038835-3038915 34 1.45e-04 aagggatcct tttgcctt ggcctcgcaa chr20:44993422-44993502 36 1.45e-04 TCTCATGGGC TTTTTCTT CTGGGAGCTC chr2:113770163-113770243 19 1.45e-04 attattgatg tttttctt aacttctttg chr4:75023298-75023378 60 1.73e-04 TCCACACACC TTTGTTCT TTTCTCCAAC chr3:142298352-142298432 70 1.73e-04 TATGTTTACA TTTGTTCT TTG chr21:38452124-38452204 33 1.73e-04 ctttttaatc tctgtttt atttgtatat chr2:15696226-15696306 62 2.14e-04 ACGCCAAAGG TCTCTTTT ATGGAACTAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTSTTTT MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:120718090-120718170 1.5e-05 15_[+2]_57 chr11:20384885-20384965 1.5e-05 58_[+2]_14 chr19:13264988-13265068 1.5e-05 39_[+2]_33 chr17:45144390-45144470 1.5e-05 63_[+2]_9 chr5:154215148-154215228 1.5e-05 [+2]_72 chr7:16779577-16779657 1.5e-05 72_[+2] chr5:28812819-28812899 1.5e-05 37_[+2]_35 chr1:44115266-44115346 1.5e-05 65_[+2]_7 chr2:69878533-69878613 3e-05 1_[+2]_71 chr19:45928106-45928186 3e-05 70_[+2]_2 chr1:15116506-15116586 6e-05 1_[+2]_71 chr6:37393967-37394047 6e-05 43_[+2]_29 chr3:151960602-151960682 6e-05 28_[+2]_44 chr22:18155575-18155655 6e-05 23_[+2]_49 chr7:127031600-127031680 6e-05 31_[+2]_41 chr1:179199821-179199901 6e-05 51_[+2]_21 chr5:149085851-149085931 8.8e-05 48_[+2]_24 chr22:17081652-17081732 8.8e-05 14_[+2]_58 chr6:108887208-108887288 8.8e-05 20_[+2]_52 chr1:157015054-157015134 0.0001 69_[+2]_3 chr7:123173506-123173586 0.0001 27_[+2]_45 chr7:14032029-14032109 0.0001 9_[+2]_63 chr18:3038835-3038915 0.00014 33_[+2]_39 chr20:44993422-44993502 0.00014 35_[+2]_37 chr2:113770163-113770243 0.00014 18_[+2]_54 chr4:75023298-75023378 0.00017 59_[+2]_13 chr3:142298352-142298432 0.00017 69_[+2]_3 chr21:38452124-38452204 0.00017 32_[+2]_40 chr2:15696226-15696306 0.00021 61_[+2]_11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTSTTTT MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTSTTTT width=8 seqs=29 chr7:120718090-120718170 ( 16) TTTGTTTT 1 chr11:20384885-20384965 ( 59) TTTGTTTT 1 chr19:13264988-13265068 ( 40) TTTGTTTT 1 chr17:45144390-45144470 ( 64) TTTGTTTT 1 chr5:154215148-154215228 ( 1) TTTGTTTT 1 chr7:16779577-16779657 ( 73) TTTGTTTT 1 chr5:28812819-28812899 ( 38) TTTGTTTT 1 chr1:44115266-44115346 ( 66) TTTGTTTT 1 chr2:69878533-69878613 ( 2) TTTCTTTT 1 chr19:45928106-45928186 ( 71) TTTCTTTT 1 chr1:15116506-15116586 ( 2) TTTTTTTT 1 chr6:37393967-37394047 ( 44) TTTTTTTT 1 chr3:151960602-151960682 ( 29) TTTTTTTT 1 chr22:18155575-18155655 ( 24) TTTGCTTT 1 chr7:127031600-127031680 ( 32) TTTGCTTT 1 chr1:179199821-179199901 ( 52) TTTGCTTT 1 chr5:149085851-149085931 ( 49) TTTCCTTT 1 chr22:17081652-17081732 ( 15) TTTCCTTT 1 chr6:108887208-108887288 ( 21) TTTCCTTT 1 chr1:157015054-157015134 ( 70) TTTCTCTT 1 chr7:123173506-123173586 ( 28) TTTCTCTT 1 chr7:14032029-14032109 ( 10) TTTCTCTT 1 chr18:3038835-3038915 ( 34) TTTGCCTT 1 chr20:44993422-44993502 ( 36) TTTTTCTT 1 chr2:113770163-113770243 ( 19) TTTTTCTT 1 chr4:75023298-75023378 ( 60) TTTGTTCT 1 chr3:142298352-142298432 ( 70) TTTGTTCT 1 chr21:38452124-38452204 ( 33) TCTGTTTT 1 chr2:15696226-15696306 ( 62) TCTCTTTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTSTTTT MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.5458 E= 1.2e+000 -1150 -1150 -1150 200 -1150 -177 -1150 189 -1150 -1150 -1150 200 -1150 40 112 -54 -1150 3 -1150 160 -1150 -19 -1150 166 -1150 -177 -1150 189 -1150 -1150 -1150 200 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTSTTTT MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 29 E= 1.2e+000 0.000000 0.000000 0.000000 1.000000 0.000000 0.068966 0.000000 0.931034 0.000000 0.000000 0.000000 1.000000 0.000000 0.310345 0.517241 0.172414 0.000000 0.241379 0.000000 0.758621 0.000000 0.206897 0.000000 0.793103 0.000000 0.068966 0.000000 0.931034 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTSTTTT MEME-2 regular expression -------------------------------------------------------------------------------- TTT[GC][TC][TC]TT -------------------------------------------------------------------------------- Time 8.77 secs. ******************************************************************************** ******************************************************************************** MOTIF CHKYCTCC MEME-3 width = 8 sites = 21 llr = 187 E-value = 4.0e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CHKYCTCC MEME-3 Description -------------------------------------------------------------------------------- Simplified A :3:::::: pos.-specific C a4:6a:aa probability G ::5::::: matrix T :354:a:: bits 2.1 * **** 1.9 * **** 1.7 * **** 1.5 * **** Relative 1.3 * **** Entropy 1.0 * ****** (12.9 bits) 0.8 * ****** 0.6 * ****** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCTCCTCC consensus AGT sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CHKYCTCC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:37211453-37211533 6 2.12e-05 aacct ccgcctcc tgggttcaag chr7:137650540-137650620 62 2.12e-05 CTGAATCTAG CCTCCTCC TCTAGGGCAG chr7:156741973-156742053 1 2.12e-05 . ccgcctcc gtggttcaag chr6:2846383-2846463 38 2.12e-05 actgcaacct ccgcctcc caggttcaag chr11:64084740-64084820 4 2.12e-05 CGG CCGCCTCC AGGAACGCCG chr19:13209317-13209397 7 2.12e-05 tctgct cctcctcc ttcagcctgg chr7:100034566-100034646 18 6.86e-05 tctcctgcct cagcctcc tgagtagctg chr6:30293710-30293790 56 6.86e-05 ACCTCACCCA CTTCCTCC AAAATCACTG chr1:167895900-167895980 20 6.86e-05 tgctgttaaa catcctcc aatgcgcagg chr10:75126470-75126550 28 6.86e-05 gctctcatat ctgcctcc cgaaaataag chr6:40995511-40995591 27 6.86e-05 CTCTCCCCAA CATCCTCC GTGAAGCATT chr6:150188876-150188956 61 6.86e-05 ctggctgcct cagcctcc caaagtgcta chr2:71222308-71222388 13 6.86e-05 TCCCCAGAAC CTGCCTCC CGGCAGGTTG chr3:47517768-47517848 12 9.12e-05 taggagacct ccgtctcc acaagtaaaa chr4:75023298-75023378 45 9.12e-05 AGGTTTTGCT CCTTCTCC ACACACCTTT chr6:26337387-26337467 34 1.42e-04 aaccttttgt cattctcc cattggctaa chr20:60962610-60962690 45 1.42e-04 TCACTGCGCC CTTTCTCC ACAGCTCCGC chr19:19515482-19515562 3 1.42e-04 ct ctgtctcc aaaaaaaaga chr6:37393967-37394047 2 1.42e-04 a ctttctcc acatcttcct chr19:7991232-7991312 34 1.42e-04 CCTGTGCCTG CATTCTCC TCCGCGATAG chr1:179199821-179199901 22 1.42e-04 AAATCTTGAT CATTCTCC TGTTATTCTT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CHKYCTCC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:37211453-37211533 2.1e-05 5_[+3]_67 chr7:137650540-137650620 2.1e-05 61_[+3]_11 chr7:156741973-156742053 2.1e-05 [+3]_72 chr6:2846383-2846463 2.1e-05 37_[+3]_35 chr11:64084740-64084820 2.1e-05 3_[+3]_69 chr19:13209317-13209397 2.1e-05 6_[+3]_66 chr7:100034566-100034646 6.9e-05 17_[+3]_55 chr6:30293710-30293790 6.9e-05 55_[+3]_17 chr1:167895900-167895980 6.9e-05 19_[+3]_53 chr10:75126470-75126550 6.9e-05 27_[+3]_45 chr6:40995511-40995591 6.9e-05 26_[+3]_46 chr6:150188876-150188956 6.9e-05 60_[+3]_12 chr2:71222308-71222388 6.9e-05 12_[+3]_60 chr3:47517768-47517848 9.1e-05 11_[+3]_61 chr4:75023298-75023378 9.1e-05 44_[+3]_28 chr6:26337387-26337467 0.00014 33_[+3]_39 chr20:60962610-60962690 0.00014 44_[+3]_28 chr19:19515482-19515562 0.00014 2_[+3]_70 chr6:37393967-37394047 0.00014 1_[+3]_71 chr19:7991232-7991312 0.00014 33_[+3]_39 chr1:179199821-179199901 0.00014 21_[+3]_51 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CHKYCTCC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CHKYCTCC width=8 seqs=21 chr6:37211453-37211533 ( 6) CCGCCTCC 1 chr7:137650540-137650620 ( 62) CCTCCTCC 1 chr7:156741973-156742053 ( 1) CCGCCTCC 1 chr6:2846383-2846463 ( 38) CCGCCTCC 1 chr11:64084740-64084820 ( 4) CCGCCTCC 1 chr19:13209317-13209397 ( 7) CCTCCTCC 1 chr7:100034566-100034646 ( 18) CAGCCTCC 1 chr6:30293710-30293790 ( 56) CTTCCTCC 1 chr1:167895900-167895980 ( 20) CATCCTCC 1 chr10:75126470-75126550 ( 28) CTGCCTCC 1 chr6:40995511-40995591 ( 27) CATCCTCC 1 chr6:150188876-150188956 ( 61) CAGCCTCC 1 chr2:71222308-71222388 ( 13) CTGCCTCC 1 chr3:47517768-47517848 ( 12) CCGTCTCC 1 chr4:75023298-75023378 ( 45) CCTTCTCC 1 chr6:26337387-26337467 ( 34) CATTCTCC 1 chr20:60962610-60962690 ( 45) CTTTCTCC 1 chr19:19515482-19515562 ( 3) CTGTCTCC 1 chr6:37393967-37394047 ( 2) CTTTCTCC 1 chr19:7991232-7991312 ( 34) CATTCTCC 1 chr1:179199821-179199901 ( 22) CATTCTCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CHKYCTCC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.2675 E= 4.0e+002 -1104 209 -1104 -1104 28 69 -1104 19 -1104 -1104 100 106 -1104 139 -1104 60 -1104 209 -1104 -1104 -1104 -1104 -1104 200 -1104 209 -1104 -1104 -1104 209 -1104 -1104 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CHKYCTCC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 21 E= 4.0e+002 0.000000 1.000000 0.000000 0.000000 0.333333 0.380952 0.000000 0.285714 0.000000 0.000000 0.476190 0.523810 0.000000 0.619048 0.000000 0.380952 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CHKYCTCC MEME-3 regular expression -------------------------------------------------------------------------------- C[CAT][TG][CT]CTCC -------------------------------------------------------------------------------- Time 12.46 secs. ******************************************************************************** ******************************************************************************** MOTIF AAARRAAA MEME-4 width = 8 sites = 47 llr = 355 E-value = 4.2e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAARRAAA MEME-4 Description -------------------------------------------------------------------------------- Simplified A a8a366aa pos.-specific C :::1:1:: probability G :2:643:: matrix T :::::::: bits 2.1 1.9 * * * 1.7 * * ** 1.5 * * ** Relative 1.3 *** ** Entropy 1.0 *** * ** (10.9 bits) 0.8 *** **** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AAAGAAAA consensus AGG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAARRAAA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:67515530-67515610 31 2.84e-05 gctaaaccaa aaagaaaa accccatctc chr6:31775039-31775119 29 2.84e-05 CAGCTGATAA AAAGAAAA AAAggccgag chr19:1480554-1480634 71 2.84e-05 ggagagagag aaagaaaa aa chr1:174972590-174972670 54 2.84e-05 ACTTGTAGTA AAAGAAAA GAATTAGTTC chr1:150847172-150847252 59 2.84e-05 AAACAAAGAA AAAGAAAA AGGAAATCTA chr3:37270990-37271070 37 2.84e-05 ggaaagaaag aaagaaaa aaaagaaaga chr11:18763495-18763575 42 2.84e-05 gtcctgcagc aaagaaaA CCACCCAAAC chr19:19515482-19515562 23 2.84e-05 aaaaaagaaa aaagaaaa cagtacgttg chr22:19815023-19815103 22 2.84e-05 gcaaacaccg aaagaaaa ataagcaaaa chr7:106649390-106649470 47 2.84e-05 TTATTACCAC AAAGAAAA CTAGGTGCAC chr2:158649867-158649947 11 2.84e-05 AAAAAACAAG AAAGAAAA GAATGTGGCA chr6:13662587-13662667 62 2.84e-05 aaattccaga aaagaaaa agaatcaata chr1:198127013-198127093 71 5.31e-05 AAGGGTAGCC AAAGGAAA AC chr9:139683251-139683331 63 5.31e-05 gagactgaga aaaggaaa taagacacaa chr1:246377667-246377747 72 5.31e-05 GAGGTAAAAC AAAGGAAA A chr6:4794683-4794763 38 7.78e-05 ggtttcatgg aaagagaa ctgggagtgc chr5:108064493-108064573 59 1.11e-04 TACACACCAA AAAAAAAA GAGAGAGAGA chr11:58939299-58939379 7 1.11e-04 TAAGGA AAAAAAAA GAGAGAGAGA chr1:205781072-205781152 62 1.11e-04 aagtagcaat aaaaaaaa cccaaaacaa chr1:11864496-11864576 12 1.11e-04 tccatctcaa aaaaaaaa acaaaaacaa chr15:52274116-52274196 13 1.32e-04 TTAAGAATAC AAAGGGAA AGGAGTGACA chr3:39449763-39449843 11 1.32e-04 GCAGATTATA AAAGGGAA AGAGTGGCAG chr22:20823468-20823548 19 1.32e-04 AGGCCAGGCA AAAGGGAA GGAAATGGAA chr9:94670230-94670310 3 1.32e-04 AT AAAGGGAA AGGTGACTAT chr2:183899176-183899256 61 1.60e-04 ATGGTGGAGG AAAAGAAA GGAGAAGGAA chr3:40409971-40410051 1 1.60e-04 . aaaagaaa taacaaaaat chr15:96226883-96226963 28 1.60e-04 GGGAAGTaag aaaagaaa caataaaatg chr17:45267362-45267442 26 2.14e-04 AAATTAGAGG AAAAAGAA GTATAGGAAA chr1:46987632-46987712 45 2.88e-04 AAGTGCCACT AAACAAAA GTAGACTCAG chr22:19023362-19023442 62 2.88e-04 AGGGGAGCTT AGAGGAAA TGGCGCTGAC chr6:16259635-16259715 55 2.88e-04 aagaaaaata aaacaaaa tagtggtaaa chr1:167833737-167833817 73 2.88e-04 aaacagaggc aaaaggaa chr12:46751881-46751961 66 2.88e-04 aaacaaaaca aaacaaaa caaaaAA chr2:27303910-27303990 15 3.34e-04 GCTCTATGCC AGAGAGAA GAGAGGGGCA chr22:19417897-19417977 53 3.34e-04 ACCAAATTCA AAACGAAA AAGCCACATG chr16:3071672-3071752 3 3.34e-04 GG AGAGAGAA GTTCACCAGT chr1:19535819-19535899 62 3.87e-04 CGCTGTGCAA AAAGACAA AAACACACAA chr1:157015054-157015134 11 3.87e-04 CCTTTTTCTG AAAGACAA TTTCCTGAGT chr1:179027952-179028032 63 3.87e-04 TTGAGAGAGA AGAAAAAA TTAAGAATGA chr6:16169163-16169243 35 4.30e-04 aggtgctgga agagggaa ctcttgggag chr22:19815711-19815791 48 4.30e-04 tatatggggc aaacagaa acaataagaa chr6:31644433-31644513 9 4.75e-04 CCTCCACC AGAAGAAA GAGACATACC chr10:88963705-88963785 22 5.21e-04 TAATTCACAC AGAAAGAA GGATGGTAGG chr11:9635440-9635520 12 5.49e-04 TTCAAACACG AAAAACAA ACTCTTCTTT chr1:23806046-23806126 47 5.95e-04 ttaaaaatta agaaggaa atcctttcta chr1:150534328-150534408 27 5.95e-04 AAAGTGGCTG AGAAGGAA GAATTTGGAC chr11:33963754-33963834 59 7.90e-04 GAGGTGGCTC AAAGGAAG AAGGAGTTAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAARRAAA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:67515530-67515610 2.8e-05 30_[+4]_42 chr6:31775039-31775119 2.8e-05 28_[+4]_44 chr19:1480554-1480634 2.8e-05 70_[+4]_2 chr1:174972590-174972670 2.8e-05 53_[+4]_19 chr1:150847172-150847252 2.8e-05 58_[+4]_14 chr3:37270990-37271070 2.8e-05 36_[+4]_36 chr11:18763495-18763575 2.8e-05 41_[+4]_31 chr19:19515482-19515562 2.8e-05 22_[+4]_50 chr22:19815023-19815103 2.8e-05 21_[+4]_51 chr7:106649390-106649470 2.8e-05 46_[+4]_26 chr2:158649867-158649947 2.8e-05 10_[+4]_62 chr6:13662587-13662667 2.8e-05 61_[+4]_11 chr1:198127013-198127093 5.3e-05 70_[+4]_2 chr9:139683251-139683331 5.3e-05 62_[+4]_10 chr1:246377667-246377747 5.3e-05 71_[+4]_1 chr6:4794683-4794763 7.8e-05 37_[+4]_35 chr5:108064493-108064573 0.00011 58_[+4]_14 chr11:58939299-58939379 0.00011 6_[+4]_66 chr1:205781072-205781152 0.00011 61_[+4]_11 chr1:11864496-11864576 0.00011 11_[+4]_61 chr15:52274116-52274196 0.00013 12_[+4]_60 chr3:39449763-39449843 0.00013 10_[+4]_62 chr22:20823468-20823548 0.00013 18_[+4]_54 chr9:94670230-94670310 0.00013 2_[+4]_70 chr2:183899176-183899256 0.00016 60_[+4]_12 chr3:40409971-40410051 0.00016 [+4]_72 chr15:96226883-96226963 0.00016 27_[+4]_45 chr17:45267362-45267442 0.00021 25_[+4]_47 chr1:46987632-46987712 0.00029 44_[+4]_28 chr22:19023362-19023442 0.00029 61_[+4]_11 chr6:16259635-16259715 0.00029 54_[+4]_18 chr1:167833737-167833817 0.00029 72_[+4] chr12:46751881-46751961 0.00029 65_[+4]_7 chr2:27303910-27303990 0.00033 14_[+4]_58 chr22:19417897-19417977 0.00033 52_[+4]_20 chr16:3071672-3071752 0.00033 2_[+4]_70 chr1:19535819-19535899 0.00039 61_[+4]_11 chr1:157015054-157015134 0.00039 10_[+4]_62 chr1:179027952-179028032 0.00039 62_[+4]_10 chr6:16169163-16169243 0.00043 34_[+4]_38 chr22:19815711-19815791 0.00043 47_[+4]_25 chr6:31644433-31644513 0.00048 8_[+4]_64 chr10:88963705-88963785 0.00052 21_[+4]_51 chr11:9635440-9635520 0.00055 11_[+4]_61 chr1:23806046-23806126 0.0006 46_[+4]_26 chr1:150534328-150534408 0.0006 26_[+4]_46 chr11:33963754-33963834 0.00079 58_[+4]_14 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAARRAAA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAARRAAA width=8 seqs=47 chr16:67515530-67515610 ( 31) AAAGAAAA 1 chr6:31775039-31775119 ( 29) AAAGAAAA 1 chr19:1480554-1480634 ( 71) AAAGAAAA 1 chr1:174972590-174972670 ( 54) AAAGAAAA 1 chr1:150847172-150847252 ( 59) AAAGAAAA 1 chr3:37270990-37271070 ( 37) AAAGAAAA 1 chr11:18763495-18763575 ( 42) AAAGAAAA 1 chr19:19515482-19515562 ( 23) AAAGAAAA 1 chr22:19815023-19815103 ( 22) AAAGAAAA 1 chr7:106649390-106649470 ( 47) AAAGAAAA 1 chr2:158649867-158649947 ( 11) AAAGAAAA 1 chr6:13662587-13662667 ( 62) AAAGAAAA 1 chr1:198127013-198127093 ( 71) AAAGGAAA 1 chr9:139683251-139683331 ( 63) AAAGGAAA 1 chr1:246377667-246377747 ( 72) AAAGGAAA 1 chr6:4794683-4794763 ( 38) AAAGAGAA 1 chr5:108064493-108064573 ( 59) AAAAAAAA 1 chr11:58939299-58939379 ( 7) AAAAAAAA 1 chr1:205781072-205781152 ( 62) AAAAAAAA 1 chr1:11864496-11864576 ( 12) AAAAAAAA 1 chr15:52274116-52274196 ( 13) AAAGGGAA 1 chr3:39449763-39449843 ( 11) AAAGGGAA 1 chr22:20823468-20823548 ( 19) AAAGGGAA 1 chr9:94670230-94670310 ( 3) AAAGGGAA 1 chr2:183899176-183899256 ( 61) AAAAGAAA 1 chr3:40409971-40410051 ( 1) AAAAGAAA 1 chr15:96226883-96226963 ( 28) AAAAGAAA 1 chr17:45267362-45267442 ( 26) AAAAAGAA 1 chr1:46987632-46987712 ( 45) AAACAAAA 1 chr22:19023362-19023442 ( 62) AGAGGAAA 1 chr6:16259635-16259715 ( 55) AAACAAAA 1 chr1:167833737-167833817 ( 73) AAAAGGAA 1 chr12:46751881-46751961 ( 66) AAACAAAA 1 chr2:27303910-27303990 ( 15) AGAGAGAA 1 chr22:19417897-19417977 ( 53) AAACGAAA 1 chr16:3071672-3071752 ( 3) AGAGAGAA 1 chr1:19535819-19535899 ( 62) AAAGACAA 1 chr1:157015054-157015134 ( 11) AAAGACAA 1 chr1:179027952-179028032 ( 63) AGAAAAAA 1 chr6:16169163-16169243 ( 35) AGAGGGAA 1 chr22:19815711-19815791 ( 48) AAACAGAA 1 chr6:31644433-31644513 ( 9) AGAAGAAA 1 chr10:88963705-88963785 ( 22) AGAAAGAA 1 chr11:9635440-9635520 ( 12) AAAAACAA 1 chr1:23806046-23806126 ( 47) AGAAGGAA 1 chr1:150534328-150534408 ( 27) AGAAGGAA 1 chr11:33963754-33963834 ( 59) AAAGGAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAARRAAA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.68137 E= 4.2e+002 186 -1220 -1220 -1220 155 -1220 -32 -1220 186 -1220 -1220 -1220 21 -115 127 -1220 116 -1220 68 -1220 121 -188 32 -1220 186 -1220 -1220 -1220 183 -1220 -348 -1220 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAARRAAA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 47 E= 4.2e+002 1.000000 0.000000 0.000000 0.000000 0.808511 0.000000 0.191489 0.000000 1.000000 0.000000 0.000000 0.000000 0.319149 0.106383 0.574468 0.000000 0.617021 0.000000 0.382979 0.000000 0.638298 0.063830 0.297872 0.000000 1.000000 0.000000 0.000000 0.000000 0.978723 0.000000 0.021277 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAARRAAA MEME-4 regular expression -------------------------------------------------------------------------------- AAA[GA][AG][AG]AA -------------------------------------------------------------------------------- Time 16.13 secs. ******************************************************************************** ******************************************************************************** MOTIF TYCHYTYT MEME-5 width = 8 sites = 34 llr = 275 E-value = 1.1e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TYCHYTYT MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::3:::: pos.-specific C :4a46:5: probability G :::::::: matrix T a6:34a5a bits 2.1 * * * * 1.9 * * * * 1.7 * * * * 1.5 * * * * Relative 1.3 * * * * Entropy 1.0 *** **** (11.7 bits) 0.8 *** **** 0.6 *** **** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTCCCTCT consensus C AT T sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCHYTYT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:50096975-50097055 23 1.23e-05 CCCCAATTCT TTCCCTCT GGGTTTGCCC chr17:45306910-45306990 5 1.23e-05 CTGC TTCCCTCT CCCCTTCTCT chr12:57909914-57909994 37 1.23e-05 GGTAACCACT TTCCCTCT GAGATGCTGT chr2:238832636-238832716 27 2.54e-05 ttcttttctt ttctctct cttctccttt chr1:15116506-15116586 20 6.44e-05 gagacagagt ttcactct tgttgcccag chr11:67764459-67764539 54 6.44e-05 CAAGGCCCCA TCCCCTCT CTCTCACATA chr20:60962610-60962690 25 6.44e-05 ACCGCCCAAG TCCCCTCT GCTCACTGCG chr4:39640985-39641065 57 6.44e-05 CTGTTATTGA TTCCCTTT ACCTTAACAT chr3:9772645-9772725 11 6.44e-05 CCCAAGTTTC TTCCCTTT CCTTCAGTCA chr8:20061504-20061584 25 6.44e-05 ACATTAAGGA TTCCCTTT CCTCATCTAc chr6:40995511-40995591 73 6.44e-05 ACTCAGCTCT TCCCCTCT chr6:31628213-31628293 29 9.07e-05 GGAATAGGAA TTCTCTTT GTTAGGAGGT chr5:139126756-139126836 34 9.07e-05 tcattttcgt tcctctct ttgtctgtct chr19:17208536-17208616 52 9.07e-05 TGAGTCATGC TTCTCTTT AGGGcagagg chr21:38452124-38452204 19 9.07e-05 atggcattaa ttctcttt ttaatctctg chr12:52278128-52278208 52 1.32e-04 tatgagggtg ttcacttt ggcattattt chr17:46986751-46986831 46 1.32e-04 CCCAAAGCTG TCCACTCT TACGCCTCTT chr6:11921693-11921773 23 1.45e-04 ccCATAAGCT TCCTCTTT GAGTATTTCT chr6:108887208-108887288 69 1.45e-04 CTAATATACT TCCTCTTT CTAC chr22:22965836-22965916 69 1.72e-04 acaTATATAT TCCACTTT CACt chr11:64084740-64084820 27 1.72e-04 CGCCGACCAC TCCACTTT AGGTATCATA chr5:149085851-149085931 31 1.72e-04 CATTTGtcct ttccttct tccttccttc chr1:145443618-145443698 5 1.86e-04 ttct ttctttct tttttttttt chr2:69878533-69878613 37 2.28e-04 CTGCCAGCTC TTCCTTTT TACCTCAATC chr6:28740146-28740226 56 2.28e-04 atgggggcct tcccttct tgacctctcc chr6:44424228-44424308 47 2.28e-04 GCAGAACATG TTCATTCT CAACTGTCAT chr19:45928106-45928186 63 2.56e-04 taatgataAA ttcttttt tttctttttt chr7:14032029-14032109 64 2.56e-04 ATCTCTTCTG TCCTTTCT ATGCCTTGA chr1:23806046-23806126 56 2.56e-04 aagaaggaaa tcctttct aaaacaagat chr21:45431152-45431232 63 2.99e-04 aacactgact tccattct ttataatgtt chr6:31870504-31870584 37 2.99e-04 CGCCCTCCCC TCCATTCT CAGGATTGAT chr19:13264988-13265068 71 2.99e-04 AGGGTCGGAC TTCATTTT GT chr6:32163047-32163127 71 2.99e-04 CTCACAACCC TTCATTTT GG chr1:161591152-161591232 36 3.28e-04 ACAGAGAGCA TCCATTTT GGATTCCCCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCHYTYT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:50096975-50097055 1.2e-05 22_[+5]_50 chr17:45306910-45306990 1.2e-05 4_[+5]_68 chr12:57909914-57909994 1.2e-05 36_[+5]_36 chr2:238832636-238832716 2.5e-05 26_[+5]_46 chr1:15116506-15116586 6.4e-05 19_[+5]_53 chr11:67764459-67764539 6.4e-05 53_[+5]_19 chr20:60962610-60962690 6.4e-05 24_[+5]_48 chr4:39640985-39641065 6.4e-05 56_[+5]_16 chr3:9772645-9772725 6.4e-05 10_[+5]_62 chr8:20061504-20061584 6.4e-05 24_[+5]_48 chr6:40995511-40995591 6.4e-05 72_[+5] chr6:31628213-31628293 9.1e-05 28_[+5]_44 chr5:139126756-139126836 9.1e-05 33_[+5]_39 chr19:17208536-17208616 9.1e-05 51_[+5]_21 chr21:38452124-38452204 9.1e-05 18_[+5]_54 chr12:52278128-52278208 0.00013 51_[+5]_21 chr17:46986751-46986831 0.00013 45_[+5]_27 chr6:11921693-11921773 0.00014 22_[+5]_50 chr6:108887208-108887288 0.00014 68_[+5]_4 chr22:22965836-22965916 0.00017 68_[+5]_4 chr11:64084740-64084820 0.00017 26_[+5]_46 chr5:149085851-149085931 0.00017 30_[+5]_42 chr1:145443618-145443698 0.00019 4_[+5]_68 chr2:69878533-69878613 0.00023 36_[+5]_36 chr6:28740146-28740226 0.00023 55_[+5]_17 chr6:44424228-44424308 0.00023 46_[+5]_26 chr19:45928106-45928186 0.00026 62_[+5]_10 chr7:14032029-14032109 0.00026 63_[+5]_9 chr1:23806046-23806126 0.00026 55_[+5]_17 chr21:45431152-45431232 0.0003 62_[+5]_10 chr6:31870504-31870584 0.0003 36_[+5]_36 chr19:13264988-13265068 0.0003 70_[+5]_2 chr6:32163047-32163127 0.0003 70_[+5]_2 chr1:161591152-161591232 0.00033 35_[+5]_37 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCHYTYT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TYCHYTYT width=8 seqs=34 chr19:50096975-50097055 ( 23) TTCCCTCT 1 chr17:45306910-45306990 ( 5) TTCCCTCT 1 chr12:57909914-57909994 ( 37) TTCCCTCT 1 chr2:238832636-238832716 ( 27) TTCTCTCT 1 chr1:15116506-15116586 ( 20) TTCACTCT 1 chr11:67764459-67764539 ( 54) TCCCCTCT 1 chr20:60962610-60962690 ( 25) TCCCCTCT 1 chr4:39640985-39641065 ( 57) TTCCCTTT 1 chr3:9772645-9772725 ( 11) TTCCCTTT 1 chr8:20061504-20061584 ( 25) TTCCCTTT 1 chr6:40995511-40995591 ( 73) TCCCCTCT 1 chr6:31628213-31628293 ( 29) TTCTCTTT 1 chr5:139126756-139126836 ( 34) TCCTCTCT 1 chr19:17208536-17208616 ( 52) TTCTCTTT 1 chr21:38452124-38452204 ( 19) TTCTCTTT 1 chr12:52278128-52278208 ( 52) TTCACTTT 1 chr17:46986751-46986831 ( 46) TCCACTCT 1 chr6:11921693-11921773 ( 23) TCCTCTTT 1 chr6:108887208-108887288 ( 69) TCCTCTTT 1 chr22:22965836-22965916 ( 69) TCCACTTT 1 chr11:64084740-64084820 ( 27) TCCACTTT 1 chr5:149085851-149085931 ( 31) TTCCTTCT 1 chr1:145443618-145443698 ( 5) TTCTTTCT 1 chr2:69878533-69878613 ( 37) TTCCTTTT 1 chr6:28740146-28740226 ( 56) TCCCTTCT 1 chr6:44424228-44424308 ( 47) TTCATTCT 1 chr19:45928106-45928186 ( 63) TTCTTTTT 1 chr7:14032029-14032109 ( 64) TCCTTTCT 1 chr1:23806046-23806126 ( 56) TCCTTTCT 1 chr21:45431152-45431232 ( 63) TCCATTCT 1 chr6:31870504-31870584 ( 37) TCCATTCT 1 chr19:13264988-13265068 ( 71) TTCATTTT 1 chr6:32163047-32163127 ( 71) TTCATTTT 1 chr1:161591152-161591232 ( 36) TCCATTTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCHYTYT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0846 E= 1.1e+003 -1173 -1173 -1173 200 -1173 90 -1173 116 -1173 209 -1173 -1173 23 58 -1173 37 -1173 139 -1173 61 -1173 -1173 -1173 200 -1173 117 -1173 91 -1173 -1173 -1173 200 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCHYTYT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 34 E= 1.1e+003 0.000000 0.000000 0.000000 1.000000 0.000000 0.441176 0.000000 0.558824 0.000000 1.000000 0.000000 0.000000 0.323529 0.352941 0.000000 0.323529 0.000000 0.617647 0.000000 0.382353 0.000000 0.000000 0.000000 1.000000 0.000000 0.529412 0.000000 0.470588 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYCHYTYT MEME-5 regular expression -------------------------------------------------------------------------------- T[TC]C[CAT][CT]T[CT]T -------------------------------------------------------------------------------- Time 19.69 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:100243-100323 8.84e-01 80 chrX:69657917-69657997 2.95e-01 80 chr11:70694609-70694689 5.70e-01 80 chr16:20752451-20752531 6.19e-01 80 chr3:37000765-37000845 2.15e-01 80 chr1:25278872-25278952 9.58e-01 80 chr10:134367162-13436724 3.84e-01 80 chr14:103811707-10381178 3.24e-01 80 chr2:113770163-113770243 1.47e-01 80 chr1:235369963-235370043 9.09e-01 80 chr19:50886994-50887074 7.66e-01 80 chr9:94670230-94670310 1.72e-01 80 chr1:184724547-184724627 4.10e-01 80 chr1:36714397-36714477 9.78e-01 80 chr6:149866723-149866803 6.35e-01 80 chr1:179199821-179199901 4.34e-03 51_[+2(5.97e-05)]_21 chr7:127031600-127031680 3.38e-02 31_[+2(5.97e-05)]_41 chr22:19390297-19390377 9.01e-01 80 chr6:31644433-31644513 1.24e-01 80 chr6:168226731-168226811 6.48e-01 80 chr12:46751881-46751961 3.91e-02 80 chr6:4794683-4794763 1.05e-02 37_[+4(7.78e-05)]_35 chr10:74452891-74452971 9.45e-02 80 chr2:71222308-71222388 1.23e-02 12_[+3(6.86e-05)]_60 chr1:150534328-150534408 1.30e-01 80 chr19:4470501-4470581 2.88e-02 80 chr1:23806046-23806126 4.12e-02 80 chr19:7991232-7991312 5.01e-03 13_[+1(9.25e-05)]_59 chr19:7713575-7713655 1.83e-02 6_[+1(4.48e-05)]_66 chr22:20823468-20823548 4.31e-01 80 chr7:120629134-120629214 5.54e-01 80 chr6:13662587-13662667 3.62e-02 61_[+4(2.84e-05)]_11 chr20:50053933-50054013 1.36e-01 80 chr1:44115266-44115346 1.77e-04 65_[+2(1.50e-05)]_7 chr12:112554771-11255485 9.30e-01 80 chr7:14032029-14032109 5.28e-03 80 chr17:56066118-56066198 5.51e-02 80 chr7:75508817-75508897 1.26e-02 80 chr12:57909914-57909994 1.18e-02 36_[+5(1.23e-05)]_36 chr6:44424228-44424308 4.30e-02 80 chr22:19159756-19159836 8.56e-01 80 chr3:39449763-39449843 5.01e-01 80 chr1:246377667-246377747 2.45e-01 23_[+4(5.31e-05)]_40_[+4(5.31e-05)]_\ 1 chr1:11864496-11864576 1.35e-01 80 chr22:22849755-22849835 8.55e-01 80 chr1:70876362-70876442 5.54e-01 80 chr5:28812819-28812899 5.67e-02 37_[+2(1.50e-05)]_35 chr16:14013373-14013453 2.01e-02 41_[+1(9.25e-05)]_31 chr15:32933869-32933949 2.13e-01 80 chr7:76009813-76009893 2.25e-01 80 chr10:29111457-29111537 7.38e-02 80 chr1:167833737-167833817 9.48e-02 80 chr7:138794938-138795018 1.65e-01 80 chr16:85085044-85085124 1.11e-02 80 chr6:28740146-28740226 2.11e-02 80 chr10:75716941-75717021 8.17e-02 80 chr16:3071672-3071752 6.67e-04 37_[+1(4.48e-05)]_35 chr15:96226883-96226963 5.41e-01 80 chr22:21450136-21450216 9.76e-01 80 chr2:158649867-158649947 1.22e-01 10_[+4(2.84e-05)]_62 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********************************************************************************