******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/CHAMP1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr4:79721047-79721127 1.0000 80 chr4:80920325-80920405 1.0000 80 chr6:139825411-139825491 1.0000 80 chr21:22576328-22576408 1.0000 80 chr1:197721950-197722030 1.0000 80 chr15:96308542-96308622 1.0000 80 chr6:49610677-49610757 1.0000 80 chr7:111073626-111073706 1.0000 80 chr19:966877-966957 1.0000 80 chr7:111077400-111077480 1.0000 80 chr7:106145251-106145331 1.0000 80 chr6:118918101-118918181 1.0000 80 chr6:135388045-135388125 1.0000 80 chr6:143515479-143515559 1.0000 80 chr11:16411277-16411357 1.0000 80 chr4:74069213-74069293 1.0000 80 chr6:49590807-49590887 1.0000 80 chr2:130986558-130986638 1.0000 80 chr10:22702212-22702292 1.0000 80 chr2:152489862-152489942 1.0000 80 chr1:191980796-191980876 1.0000 80 chr21:15919225-15919305 1.0000 80 chr11:97863862-97863942 1.0000 80 chr21:31046795-31046875 1.0000 80 chr7:12813408-12813488 1.0000 80 chr21:30694447-30694527 1.0000 80 chr3:87862801-87862881 1.0000 80 chr4:127484672-127484752 1.0000 80 chr2:15683838-15683918 1.0000 80 chr7:110957056-110957136 1.0000 80 chr6:13670803-13670883 1.0000 80 chr21:38801872-38801952 1.0000 80 chr19:47334279-47334359 1.0000 80 chr1:197704746-197704826 1.0000 80 chr12:70656225-70656305 1.0000 80 chr3:171752963-171753043 1.0000 80 chr12:1308176-1308256 1.0000 80 chr6:99392174-99392254 1.0000 80 chr22:37912584-37912664 1.0000 80 chr7:141452605-141452685 1.0000 80 chr4:48354958-48355038 1.0000 80 chr5:65447852-65447932 1.0000 80 chr18:2230817-2230897 1.0000 80 chr2:48548438-48548518 1.0000 80 chr12:33813003-33813083 1.0000 80 chr21:22546362-22546442 1.0000 80 chr4:73274439-73274519 1.0000 80 chr11:97819986-97820066 1.0000 80 chr7:111043229-111043309 1.0000 80 chr3:152774698-152774778 1.0000 80 chr7:13121711-13121791 1.0000 80 chr2:58448077-58448157 1.0000 80 chr2:69953258-69953338 1.0000 80 chr1:160588719-160588799 1.0000 80 chr17:57860336-57860416 1.0000 80 chr7:123340017-123340097 1.0000 80 chr12:23848651-23848731 1.0000 80 chr4:48769304-48769384 1.0000 80 chr5:90578222-90578302 1.0000 80 chr6:11933216-11933296 1.0000 80 chr6:147858710-147858790 1.0000 80 chr6:125414768-125414848 1.0000 80 chr5:61888589-61888669 1.0000 80 chr12:77173303-77173383 1.0000 80 chr2:170712345-170712425 1.0000 80 chr6:17976672-17976752 1.0000 80 chr6:49609667-49609747 1.0000 80 chr21:16110397-16110477 1.0000 80 chr1:89997965-89998045 1.0000 80 chr7:14087715-14087795 1.0000 80 chr7:12971264-12971344 1.0000 80 chr2:15659060-15659140 1.0000 80 chr11:58536985-58537065 1.0000 80 chr2:48550464-48550544 1.0000 80 chr1:28388277-28388357 1.0000 80 chr7:7175734-7175814 1.0000 80 chr3:152029666-152029746 1.0000 80 chr4:140626374-140626454 1.0000 80 chr10:11589713-11589793 1.0000 80 chr18:28252512-28252592 1.0000 80 chr6:68719104-68719184 1.0000 80 chr15:58390510-58390590 1.0000 80 chr9:37236575-37236655 1.0000 80 chr5:75814257-75814337 1.0000 80 chr5:56544460-56544540 1.0000 80 chr7:120699923-120700003 1.0000 80 chr8:110440921-110441001 1.0000 80 chr4:74073637-74073717 1.0000 80 chr12:28314128-28314208 1.0000 80 chr11:97784837-97784917 1.0000 80 chr5:43482084-43482164 1.0000 80 chr5:38986181-38986261 1.0000 80 chr1:194824410-194824490 1.0000 80 chr4:151224807-151224887 1.0000 80 chr15:50606587-50606667 1.0000 80 chr7:135639450-135639530 1.0000 80 chr10:22700945-22701025 1.0000 80 chr2:158061851-158061931 1.0000 80 chr8:100180534-100180614 1.0000 80 chr3:170515553-170515633 1.0000 80 chr1:185235298-185235378 1.0000 80 chr1:93968858-93968938 1.0000 80 chr2:48583427-48583507 1.0000 80 chr4:174209539-174209619 1.0000 80 chr12:96730423-96730503 1.0000 80 chr1:167241920-167242000 1.0000 80 chr1:61685257-61685337 1.0000 80 chr4:186090372-186090452 1.0000 80 chr1:192075295-192075375 1.0000 80 chr21:30684720-30684800 1.0000 80 chr1:144685427-144685507 1.0000 80 chr7:141451850-141451930 1.0000 80 chr5:118768622-118768702 1.0000 80 chr6:138043676-138043756 1.0000 80 chr5:12579072-12579152 1.0000 80 chr2:169834344-169834424 1.0000 80 chr1:61763734-61763814 1.0000 80 chr14:61401179-61401259 1.0000 80 chr6:105409431-105409511 1.0000 80 chr16:53249028-53249108 1.0000 80 chr12:62712952-62713032 1.0000 80 chr15:52295436-52295516 1.0000 80 chr7:120687849-120687929 1.0000 80 chr12:28321981-28322061 1.0000 80 chr7:119422540-119422620 1.0000 80 chr1:233799565-233799645 1.0000 80 chr2:62959547-62959627 1.0000 80 chr6:139865673-139865753 1.0000 80 chr1:32312247-32312327 1.0000 80 chr2:38585542-38585622 1.0000 80 chr4:74069782-74069862 1.0000 80 chr18:33640147-33640227 1.0000 80 chr1:212214990-212215070 1.0000 80 chr14:97304893-97304973 1.0000 80 chr9:75638015-75638095 1.0000 80 chr1:35852050-35852130 1.0000 80 chr7:12751335-12751415 1.0000 80 chr6:138177366-138177446 1.0000 80 chr1:165841087-165841167 1.0000 80 chr2:158052676-158052756 1.0000 80 chr11:95475761-95475841 1.0000 80 chr6:11912841-11912921 1.0000 80 chr3:135856559-135856639 1.0000 80 chr8:106393473-106393553 1.0000 80 chr8:110433885-110433965 1.0000 80 chr6:69457763-69457843 1.0000 80 chr2:100078676-100078756 1.0000 80 chr7:106640008-106640088 1.0000 80 chr21:30693699-30693779 1.0000 80 chr16:50312326-50312406 1.0000 80 chr6:15723140-15723220 1.0000 80 chr1:52754053-52754133 1.0000 80 chr11:5177713-5177793 1.0000 80 chr7:91884273-91884353 1.0000 80 chr3:142586043-142586123 1.0000 80 chr3:169486538-169486618 1.0000 80 chr4:129297592-129297672 1.0000 80 chr6:49708680-49708760 1.0000 80 chr2:86946885-86946965 1.0000 80 chr11:124102569-12410264 1.0000 80 chr6:129998337-129998417 1.0000 80 chr6:4844466-4844546 1.0000 80 chr11:16397386-16397466 1.0000 80 chr10:62020282-62020362 1.0000 80 chr7:103395800-103395880 1.0000 80 chr21:33065662-33065742 1.0000 80 chr9:76590207-76590287 1.0000 80 chr12:33738425-33738505 1.0000 80 chr5:171392872-171392952 1.0000 80 chr7:131049666-131049746 1.0000 80 chr7:106683103-106683183 1.0000 80 chr10:108793009-10879308 1.0000 80 chr9:94860377-94860457 1.0000 80 chr2:114737236-114737316 1.0000 80 chr14:61314930-61315010 1.0000 80 chr3:37271992-37272072 1.0000 80 chr1:8958624-8958704 1.0000 80 chr12:117003175-11700325 1.0000 80 chr2:188445478-188445558 1.0000 80 chr1:85663550-85663630 1.0000 80 chr1:28133394-28133474 1.0000 80 chr7:103589897-103589977 1.0000 80 chr3:84286734-84286814 1.0000 80 chr15:67539059-67539139 1.0000 80 chr6:68614800-68614880 1.0000 80 chr1:54277422-54277502 1.0000 80 chr2:170781334-170781414 1.0000 80 chr1:109067543-109067623 1.0000 80 chr13:113866213-11386629 1.0000 80 chr8:38232305-38232385 1.0000 80 chr2:185071516-185071596 1.0000 80 chr2:78769294-78769374 1.0000 80 chrX:89713119-89713199 1.0000 80 chr9:37211764-37211844 1.0000 80 chr2:87304078-87304158 1.0000 80 chr1:114260318-114260398 1.0000 80 chr8:103420195-103420275 1.0000 80 chr17:13415793-13415873 1.0000 80 chr6:36417113-36417193 1.0000 80 chr12:111008752-11100883 1.0000 80 chr3:49333054-49333134 1.0000 80 chr21:16096553-16096633 1.0000 80 chr1:227464245-227464325 1.0000 80 chr12:45709366-45709446 1.0000 80 chr20:46233813-46233893 1.0000 80 chr7:7717654-7717734 1.0000 80 chr7:154469906-154469986 1.0000 80 chr2:24707612-24707692 1.0000 80 chr1:115016135-115016215 1.0000 80 chr6:158247348-158247428 1.0000 80 chr1:191815053-191815133 1.0000 80 chr8:106137608-106137688 1.0000 80 chr2:48581498-48581578 1.0000 80 chr4:128709834-128709914 1.0000 80 chr4:166400892-166400972 1.0000 80 chr3:172722889-172722969 1.0000 80 chr21:15902413-15902493 1.0000 80 chr21:22782237-22782317 1.0000 80 chr15:48989283-48989363 1.0000 80 chr8:105602795-105602875 1.0000 80 chr3:151913961-151914041 1.0000 80 chr1:85660712-85660792 1.0000 80 chr11:16281701-16281781 1.0000 80 chr3:152158191-152158271 1.0000 80 chr6:105410994-105411074 1.0000 80 chr1:90450508-90450588 1.0000 80 chr1:65731549-65731629 1.0000 80 chr6:150087435-150087515 1.0000 80 chr13:79970196-79970276 1.0000 80 chr6:119582397-119582477 1.0000 80 chr9:71369267-71369347 1.0000 80 chr1:180597949-180598029 1.0000 80 chr2:11434065-11434145 1.0000 80 chr7:22380964-22381044 1.0000 80 chrX:134971291-134971371 1.0000 80 chr7:106417545-106417625 1.0000 80 chr12:62713988-62714068 1.0000 80 chr2:43954327-43954407 1.0000 80 chr8:28792202-28792282 1.0000 80 chr3:171585917-171585997 1.0000 80 chr3:24306389-24306469 1.0000 80 chr1:145095684-145095764 1.0000 80 chr21:31010694-31010774 1.0000 80 chr4:68415777-68415857 1.0000 80 chr6:28833638-28833718 1.0000 80 chr5:10740678-10740758 1.0000 80 chr4:80109523-80109603 1.0000 80 chr18:34479399-34479479 1.0000 80 chr2:223801619-223801699 1.0000 80 chr6:64284414-64284494 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_CHAMP1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/CHAMP1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.252 C 0.259 G 0.249 T 0.24 Background letter frequencies (from file dataset with add-one prior applied): A 0.252 C 0.259 G 0.249 T 0.24 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TCGWGAYC MEME-1 width = 8 sites = 63 llr = 574 E-value = 1.0e-053 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCGWGAYC MEME-1 Description -------------------------------------------------------------------------------- Simplified A :::6:a:: pos.-specific C :a1:::6a probability G ::9:a::: matrix T a::4::4: bits 2.1 * ** 1.9 ** ** * 1.6 ** ** * 1.4 ** ** * Relative 1.2 *** ** * Entropy 1.0 ******** (13.1 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCGAGACC consensus T T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCGWGAYC MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:80109523-80109603 11 1.64e-05 ggtcgggaga tcgagacc atcctggcta chr4:68415777-68415857 16 1.64e-05 ggtcaggaga tcgagacc gtcctagcta chr8:28792202-28792282 35 1.64e-05 gatcaggaga tcgagacc atcctggcta chr2:43954327-43954407 21 1.64e-05 gtcaggaaga tcgagacc atcttggcca chr2:11434065-11434145 14 1.64e-05 ggtcaggaga tcgagacc atcctggcta chr21:22782237-22782317 11 1.64e-05 ggtcaggaga tcgagacc atcctggcta chr3:172722889-172722969 18 1.64e-05 ggtcaggaga tcgagacc atcctggcca chr4:166400892-166400972 46 1.64e-05 ggtcaggaga tcgagacc atcctggcta chr8:106137608-106137688 41 1.64e-05 ggtcaggaga tcgagacc atcctggcta chr9:37211764-37211844 56 1.64e-05 ggtcaggaga tcgagacc atcctggcta chr8:38232305-38232385 12 1.64e-05 ggtcaggaga tcgagacc atcctagcta chr2:170781334-170781414 5 1.64e-05 gaaa tcgagacc atcctggcca chr3:84286734-84286814 34 1.64e-05 ggtcaggaga tcgagacc atcctggcta chr2:158052676-158052756 15 1.64e-05 ggtcaggaga tcgagacc attctggcta chr18:33640147-33640227 42 1.64e-05 ggtcaggaga tcgagacc atcctgacta chr1:144685427-144685507 45 1.64e-05 ggtcgggaga tcgagacc atcctgccta chr7:135639450-135639530 35 1.64e-05 ggtcaggaga tcgagacc atccttgcta chr12:28314128-28314208 31 1.64e-05 ggtcaggaga tcgagacc atcctggtta chr4:74073637-74073717 63 1.64e-05 ggtcaggaga tcgagacc atcctggcta chr6:68719104-68719184 66 1.64e-05 ggtcgggaga tcgagacc atcctgg chr12:23848651-23848731 19 1.64e-05 ggtcaggaga tcgagacc atcctggcta chr7:123340017-123340097 8 1.64e-05 caggagg tcgagacc atcctggcta chr17:57860336-57860416 15 1.64e-05 ggtcaggaca tcgagacc atcctggctg chr2:58448077-58448157 65 1.64e-05 ggtcaggaga tcgagacc gatcctgg chr2:48548438-48548518 31 1.64e-05 ggtcaggaga tcgagacc gtctggctaa chr6:13670803-13670883 20 1.64e-05 ggtcaggaga tcgagacc atcctggcta chr11:97863862-97863942 38 1.64e-05 ggtcaggaaa tcgagacc atcctggcta chr10:22702212-22702292 45 1.64e-05 ggtcaggaga tcgagacc gtcctggcta chr4:74069213-74069293 56 1.64e-05 ggtcaggaga tcgagacc atcctggcta chr11:16411277-16411357 32 1.64e-05 agtcggggga tcgagacc atcccggcta chr21:33065662-33065742 27 4.73e-05 TTTCTTGAGA TCGAGATC GGGGAGAATG chr20:46233813-46233893 31 6.18e-05 tctcttgacc tcgtgatc cgcccgcctt chr2:185071516-185071596 42 6.18e-05 tctcctgacc tcgtgatc ctcccacctc chr1:85663550-85663630 21 6.18e-05 tctcctgacc tcgtgatc cgcccgcctc chr3:37271992-37272072 16 6.18e-05 tctcctgacc tcgtgatc cacccgcctc chr12:33738425-33738505 69 6.18e-05 tctcctgatc tcgtgatc cgcc chr11:124102569-12410264 71 6.18e-05 tctcctgacc tcgtgatc ca chr3:169486538-169486618 12 6.18e-05 actcctgacc tcgtgatc cgccctgctc chr3:135856559-135856639 58 6.18e-05 tctcctgacc tcgtgatc cgcccacctg chr5:12579072-12579152 27 6.18e-05 tcttctgacc tcgtgatc cgcccacctc chr6:138043676-138043756 28 6.18e-05 tctcctgacc tcgtgatc cgcccgcctc chr2:158061851-158061931 51 6.18e-05 tttcctgacc tcgtgatc cgcccgcctc chr10:22700945-22701025 67 6.18e-05 tatcctgacg tcgtgatc cgcccg chr15:50606587-50606667 27 6.18e-05 tctcctcacc tcgtgatc tgcccgcctc chr11:97784837-97784917 59 6.18e-05 tctcctgatc tcgtgatc cacccgcctc chr5:56544460-56544540 35 6.18e-05 tctcctgacc tcgtgatc cgcccgcctc chr9:37236575-37236655 50 6.18e-05 tcttctgacc tcgtgatc cgcccgtctc chr10:11589713-11589793 60 6.18e-05 tctcctgacc tcgtgatc cgcccgcctt chr1:28388277-28388357 67 6.18e-05 tctcctgacc tcgtgatc cgccca chr5:65447852-65447932 55 6.18e-05 tctcctgacc tcgtgatc cgcccgcctt chr12:70656225-70656305 64 6.18e-05 tctcctgacc tcgtgatc tgcctgcct chr21:15919225-15919305 39 6.18e-05 tctcctgatc tcgtgatc cgcccacctc chr1:191980796-191980876 66 6.18e-05 atctcctaac tcgtgatc ctcccgc chr21:15902413-15902493 19 7.88e-05 ggtcaggaga tccagacc accctggcta chr11:16281701-16281781 71 9.51e-05 ggtctcgatc tcctgacc tc chr11:95475761-95475841 71 9.51e-05 gttctcgatc tcctgacc tc chr16:53249028-53249108 26 9.51e-05 ggtctcgatc tcctgacc tcgcgatccg chr6:105409431-105409511 70 9.51e-05 agtcacgagc tcctgacc ttg chr12:33813003-33813083 8 1.12e-04 caggaga tcaagacc atcctggcta chr6:49610677-49610757 49 1.12e-04 ggagacgaga tcaagacc attctggcca chr12:1308176-1308256 53 1.43e-04 caAAccaccg tcatgacc cagtcacttc chr11:5177713-5177793 72 2.05e-04 ggtctcgatc tcgcgacc t chr7:103395800-103395880 50 2.37e-04 ggtcaggaga tcgagaca atcctggcta -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCGWGAYC MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:80109523-80109603 1.6e-05 10_[+1]_62 chr4:68415777-68415857 1.6e-05 15_[+1]_57 chr8:28792202-28792282 1.6e-05 34_[+1]_38 chr2:43954327-43954407 1.6e-05 20_[+1]_52 chr2:11434065-11434145 1.6e-05 13_[+1]_59 chr21:22782237-22782317 1.6e-05 10_[+1]_62 chr3:172722889-172722969 1.6e-05 17_[+1]_55 chr4:166400892-166400972 1.6e-05 45_[+1]_27 chr8:106137608-106137688 1.6e-05 40_[+1]_32 chr9:37211764-37211844 1.6e-05 55_[+1]_17 chr8:38232305-38232385 1.6e-05 11_[+1]_61 chr2:170781334-170781414 1.6e-05 4_[+1]_68 chr3:84286734-84286814 1.6e-05 33_[+1]_39 chr2:158052676-158052756 1.6e-05 14_[+1]_58 chr18:33640147-33640227 1.6e-05 41_[+1]_31 chr1:144685427-144685507 1.6e-05 44_[+1]_28 chr7:135639450-135639530 1.6e-05 34_[+1]_38 chr12:28314128-28314208 1.6e-05 30_[+1]_42 chr4:74073637-74073717 1.6e-05 62_[+1]_10 chr6:68719104-68719184 1.6e-05 65_[+1]_7 chr12:23848651-23848731 1.6e-05 18_[+1]_54 chr7:123340017-123340097 1.6e-05 7_[+1]_65 chr17:57860336-57860416 1.6e-05 14_[+1]_58 chr2:58448077-58448157 1.6e-05 64_[+1]_8 chr2:48548438-48548518 1.6e-05 30_[+1]_42 chr6:13670803-13670883 1.6e-05 19_[+1]_53 chr11:97863862-97863942 1.6e-05 37_[+1]_35 chr10:22702212-22702292 1.6e-05 44_[+1]_28 chr4:74069213-74069293 1.6e-05 55_[+1]_17 chr11:16411277-16411357 1.6e-05 31_[+1]_41 chr21:33065662-33065742 4.7e-05 26_[+1]_46 chr20:46233813-46233893 6.2e-05 30_[+1]_42 chr2:185071516-185071596 6.2e-05 41_[+1]_31 chr1:85663550-85663630 6.2e-05 20_[+1]_52 chr3:37271992-37272072 6.2e-05 15_[+1]_57 chr12:33738425-33738505 6.2e-05 68_[+1]_4 chr11:124102569-12410264 6.2e-05 70_[+1]_2 chr3:169486538-169486618 6.2e-05 11_[+1]_61 chr3:135856559-135856639 6.2e-05 57_[+1]_15 chr5:12579072-12579152 6.2e-05 26_[+1]_46 chr6:138043676-138043756 6.2e-05 27_[+1]_45 chr2:158061851-158061931 6.2e-05 50_[+1]_22 chr10:22700945-22701025 6.2e-05 66_[+1]_6 chr15:50606587-50606667 6.2e-05 26_[+1]_46 chr11:97784837-97784917 6.2e-05 58_[+1]_14 chr5:56544460-56544540 6.2e-05 34_[+1]_38 chr9:37236575-37236655 6.2e-05 49_[+1]_23 chr10:11589713-11589793 6.2e-05 59_[+1]_13 chr1:28388277-28388357 6.2e-05 66_[+1]_6 chr5:65447852-65447932 6.2e-05 54_[+1]_18 chr12:70656225-70656305 6.2e-05 63_[+1]_9 chr21:15919225-15919305 6.2e-05 38_[+1]_34 chr1:191980796-191980876 6.2e-05 65_[+1]_7 chr21:15902413-15902493 7.9e-05 18_[+1]_54 chr11:16281701-16281781 9.5e-05 70_[+1]_2 chr11:95475761-95475841 9.5e-05 70_[+1]_2 chr16:53249028-53249108 9.5e-05 25_[+1]_47 chr6:105409431-105409511 9.5e-05 69_[+1]_3 chr12:33813003-33813083 0.00011 7_[+1]_65 chr6:49610677-49610757 0.00011 48_[+1]_24 chr12:1308176-1308256 0.00014 52_[+1]_20 chr11:5177713-5177793 0.00021 71_[+1]_1 chr7:103395800-103395880 0.00024 49_[+1]_23 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCGWGAYC MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCGWGAYC width=8 seqs=63 chr4:80109523-80109603 ( 11) TCGAGACC 1 chr4:68415777-68415857 ( 16) TCGAGACC 1 chr8:28792202-28792282 ( 35) TCGAGACC 1 chr2:43954327-43954407 ( 21) TCGAGACC 1 chr2:11434065-11434145 ( 14) TCGAGACC 1 chr21:22782237-22782317 ( 11) TCGAGACC 1 chr3:172722889-172722969 ( 18) TCGAGACC 1 chr4:166400892-166400972 ( 46) TCGAGACC 1 chr8:106137608-106137688 ( 41) TCGAGACC 1 chr9:37211764-37211844 ( 56) TCGAGACC 1 chr8:38232305-38232385 ( 12) TCGAGACC 1 chr2:170781334-170781414 ( 5) TCGAGACC 1 chr3:84286734-84286814 ( 34) TCGAGACC 1 chr2:158052676-158052756 ( 15) TCGAGACC 1 chr18:33640147-33640227 ( 42) TCGAGACC 1 chr1:144685427-144685507 ( 45) TCGAGACC 1 chr7:135639450-135639530 ( 35) TCGAGACC 1 chr12:28314128-28314208 ( 31) TCGAGACC 1 chr4:74073637-74073717 ( 63) TCGAGACC 1 chr6:68719104-68719184 ( 66) TCGAGACC 1 chr12:23848651-23848731 ( 19) TCGAGACC 1 chr7:123340017-123340097 ( 8) TCGAGACC 1 chr17:57860336-57860416 ( 15) TCGAGACC 1 chr2:58448077-58448157 ( 65) TCGAGACC 1 chr2:48548438-48548518 ( 31) TCGAGACC 1 chr6:13670803-13670883 ( 20) TCGAGACC 1 chr11:97863862-97863942 ( 38) TCGAGACC 1 chr10:22702212-22702292 ( 45) TCGAGACC 1 chr4:74069213-74069293 ( 56) TCGAGACC 1 chr11:16411277-16411357 ( 32) TCGAGACC 1 chr21:33065662-33065742 ( 27) TCGAGATC 1 chr20:46233813-46233893 ( 31) TCGTGATC 1 chr2:185071516-185071596 ( 42) TCGTGATC 1 chr1:85663550-85663630 ( 21) TCGTGATC 1 chr3:37271992-37272072 ( 16) TCGTGATC 1 chr12:33738425-33738505 ( 69) TCGTGATC 1 chr11:124102569-12410264 ( 71) TCGTGATC 1 chr3:169486538-169486618 ( 12) TCGTGATC 1 chr3:135856559-135856639 ( 58) TCGTGATC 1 chr5:12579072-12579152 ( 27) TCGTGATC 1 chr6:138043676-138043756 ( 28) TCGTGATC 1 chr2:158061851-158061931 ( 51) TCGTGATC 1 chr10:22700945-22701025 ( 67) TCGTGATC 1 chr15:50606587-50606667 ( 27) TCGTGATC 1 chr11:97784837-97784917 ( 59) TCGTGATC 1 chr5:56544460-56544540 ( 35) TCGTGATC 1 chr9:37236575-37236655 ( 50) TCGTGATC 1 chr10:11589713-11589793 ( 60) TCGTGATC 1 chr1:28388277-28388357 ( 67) TCGTGATC 1 chr5:65447852-65447932 ( 55) TCGTGATC 1 chr12:70656225-70656305 ( 64) TCGTGATC 1 chr21:15919225-15919305 ( 39) TCGTGATC 1 chr1:191980796-191980876 ( 66) TCGTGATC 1 chr21:15902413-15902493 ( 19) TCCAGACC 1 chr11:16281701-16281781 ( 71) TCCTGACC 1 chr11:95475761-95475841 ( 71) TCCTGACC 1 chr16:53249028-53249108 ( 26) TCCTGACC 1 chr6:105409431-105409511 ( 70) TCCTGACC 1 chr12:33813003-33813083 ( 8) TCAAGACC 1 chr6:49610677-49610757 ( 49) TCAAGACC 1 chr12:1308176-1308256 ( 53) TCATGACC 1 chr11:5177713-5177793 ( 72) TCGCGACC 1 chr7:103395800-103395880 ( 50) TCGAGACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCGWGAYC MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.15507 E= 1.0e-053 -1262 -1262 -1262 206 -1262 195 -1262 -1262 -240 -170 181 -1262 114 -402 -1262 84 -1262 -1262 200 -1262 199 -1262 -1262 -1262 -1262 130 -1262 60 -399 193 -1262 -1262 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCGWGAYC MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 63 E= 1.0e-053 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.047619 0.079365 0.873016 0.000000 0.555556 0.015873 0.000000 0.428571 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.634921 0.000000 0.365079 0.015873 0.984127 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCGWGAYC MEME-1 regular expression -------------------------------------------------------------------------------- TCG[AT]GA[CT]C -------------------------------------------------------------------------------- Time 4.94 secs. ******************************************************************************** ******************************************************************************** MOTIF TYAGGAGA MEME-2 width = 8 sites = 120 llr = 855 E-value = 6.9e-051 ******************************************************************************** -------------------------------------------------------------------------------- Motif TYAGGAGA MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::7::7:8 pos.-specific C :6:1:::: probability G ::3683a2 matrix T a4:32::: bits 2.1 * 1.9 * * 1.6 * * 1.4 * * Relative 1.2 * * **** Entropy 1.0 *** **** (10.3 bits) 0.8 *** **** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCAGGAGA consensus TGT G G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYAGGAGA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:68415777-68415857 8 1.54e-05 cacgagg tcaggaga tcgagaccgt chr8:28792202-28792282 27 1.54e-05 gatcacgaga tcaggaga tcgagaccat chr2:11434065-11434145 6 1.54e-05 tgagg tcaggaga tcgagaccat chr13:79970196-79970276 51 1.54e-05 cacattacat tcaggaga acaaagactc chr21:22782237-22782317 3 1.54e-05 gg tcaggaga tcgagaccat chr21:15902413-15902493 11 1.54e-05 gatcacgagg tcaggaga tccagaccac chr3:172722889-172722969 10 1.54e-05 atcacgagg tcaggaga tcgagaccat chr4:166400892-166400972 38 1.54e-05 gatcacgagg tcaggaga tcgagaccat chr8:106137608-106137688 33 1.54e-05 gcacacgagg tcaggaga tcgagaccat chr9:37211764-37211844 48 1.54e-05 gatcacgagg tcaggaga tcgagaccat chr8:38232305-38232385 4 1.54e-05 agg tcaggaga tcgagaccat chr3:84286734-84286814 26 1.54e-05 gatcacgagg tcaggaga tcgagaccat chr7:103395800-103395880 42 1.54e-05 gatcacgagg tcaggaga tcgagacaat chr2:158052676-158052756 7 1.54e-05 acgagg tcaggaga tcgagaccat chr18:33640147-33640227 34 1.54e-05 gatcacgagg tcaggaga tcgagaccat chr7:135639450-135639530 27 1.54e-05 gatcacgagg tcaggaga tcgagaccat chr12:28314128-28314208 23 1.54e-05 gatcatgggg tcaggaga tcgagaccat chr4:74073637-74073717 55 1.54e-05 gatcacgagg tcaggaga tcgagaccat chr6:49609667-49609747 2 1.54e-05 g tcaggaga ttgagaccat chr12:23848651-23848731 11 1.54e-05 gatcacgagg tcaggaga tcgagaccat chr2:58448077-58448157 57 1.54e-05 gatcacgagg tcaggaga tcgagaccga chr2:48548438-48548518 23 1.54e-05 gatcacgagg tcaggaga tcgagaccgt chr6:13670803-13670883 12 1.54e-05 gatcacgagg tcaggaga tcgagaccat chr10:22702212-22702292 37 1.54e-05 gatcacgagg tcaggaga tcgagaccgt chr4:74069213-74069293 48 1.54e-05 gatcacgagg tcaggaga tcgagaccat chr6:49610677-49610757 30 1.54e-05 gatcacgtgg tcaggaga gggagacgag chr12:62713988-62714068 59 4.44e-05 gaatgagttc tcatgaga tacggttgtt chr2:24707612-24707692 73 4.44e-05 caaataagtc tcatgaga chr1:109067543-109067623 6 4.44e-05 cacta tcatgaga acagcatggg chr1:28133394-28133474 21 4.44e-05 caaccggatc tcatgaga actccctcac chr6:138177366-138177446 66 4.44e-05 tgaataagtc tcatgaga tctgatg chr3:170515553-170515633 25 4.44e-05 ccatcatatc tcatgaga actcactcac chr5:75814257-75814337 9 4.44e-05 attcatta tcatgaga acagcacagg chr7:7175734-7175814 24 4.44e-05 tcactcacta tcatgaga acagcaggga chr2:69953258-69953338 60 4.44e-05 gtgggtgagt tcatgaga tctgatagtt chr7:106145251-106145331 31 4.44e-05 ccatcacatc tcatgaga cttgtgcact chr15:96308542-96308622 12 4.44e-05 ccactcacta tcatgaga acagcatgga chr4:80109523-80109603 3 7.47e-05 gg tcgggaga tcgagaccat chr1:144685427-144685507 37 7.47e-05 gatcacgagg tcgggaga tcgagaccat chr6:68719104-68719184 58 7.47e-05 aatcacgagg tcgggaga tcgagaccat chr1:114260318-114260398 73 1.76e-04 ccatcagatc tcgtgaga chr21:38801872-38801952 11 1.76e-04 gtactcacca tcgtgaga atagcaaggg chr1:145095684-145095764 30 2.04e-04 ttgtgttttt ttagtaga gacggggttt chr11:16281701-16281781 25 2.04e-04 tttgtatttt ttagtaga gacggggttt chr11:124102569-12410264 17 2.04e-04 ttttgtattt ttagtaga gacggggttt chr11:5177713-5177793 26 2.04e-04 ttgtattttt ttagtaga gacggggttt chr3:135856559-135856639 4 2.04e-04 ttt ttagtaga gacggggttt chr11:95475761-95475841 25 2.04e-04 ttttgtattt ttagtaga gacggggttt chr1:212214990-212215070 42 2.04e-04 ttatgtattt ttagtaga gacggggttt chr6:105409431-105409511 24 2.04e-04 ttttgtattt ttagtaga gatggggttt chr10:22700945-22701025 13 2.04e-04 ttttgtattt ttagtaga gacggggttt chr11:97784837-97784917 5 2.04e-04 attt ttagtaga gacggggttt chr10:11589713-11589793 6 2.04e-04 tattt ttagtaga gacggggtgt chr1:28388277-28388357 13 2.04e-04 ttttgtattt ttagtaga gacgcggttt chr21:22546362-22546442 54 2.04e-04 tttttgtatt ttagtaga tacgaggttt chr5:65447852-65447932 1 2.04e-04 . ttagtaga gacggggttt chr7:110957056-110957136 28 2.04e-04 ttttgtattt ttagtaga gacggggttt chr11:16411277-16411357 24 2.33e-04 gatcacgaag tcggggga tcgagaccat chr2:223801619-223801699 30 2.91e-04 tcactcacca tcacgaga acaacatgga chr7:106417545-106417625 49 2.91e-04 ccgtcagatc ttgtgaga cttgttcact chr1:180597949-180598029 48 2.91e-04 catatgggga ttatggga actaagagtc chr6:15723140-15723220 41 2.91e-04 catgtgggca ttatggga accacaggat chr15:52295436-52295516 12 2.91e-04 tcattcacta tcacgaga acagcatggg chr14:61401179-61401259 68 2.91e-04 tgaataagtc tcacgaga tctga chr1:93968858-93968938 72 2.91e-04 cacatgggga ttatggga a chr12:77173303-77173383 55 2.91e-04 cacgtgggaa ttatggga actacaattc chr7:111043229-111043309 43 2.91e-04 tagtgagtac tcacgaga tctcatggtt chr2:15683838-15683918 62 2.91e-04 cacgtgggag ttatggga gtacaaatca chr7:111073626-111073706 19 2.91e-04 cacatgggaa ttatggga gtacaattca chr1:85660712-85660792 22 3.21e-04 tcccagctac tcgggagg ctgaggcagg chr9:76590207-76590287 32 3.21e-04 tcccagctac tcgggagg ctgaggcagg chr6:49708680-49708760 25 3.21e-04 tcccagctac tcgggagg ctgaggcagg chr4:140626374-140626454 64 3.21e-04 ttagaaaatg tcaggggg taaattctg chr6:147858710-147858790 71 3.21e-04 tcccagctac tcgggagg ct chr4:127484672-127484752 72 3.21e-04 GGGCCAAATA TCGGGAGG G chr6:135388045-135388125 32 3.77e-04 atccccaatg ttggggga ggggcctggt chr12:111008752-11100883 14 4.05e-04 tcgtcccacc ttacgaga aacacccaca chr1:192075295-192075375 27 4.20e-04 tccccacatg tcgtggga gggacgcagt chr1:89997965-89998045 51 4.20e-04 tccccacgtg tcgtggga gggactgggt chr5:61888589-61888669 27 4.20e-04 ccatctgatc tcgtggga gctcactcac chr6:118918101-118918181 6 4.20e-04 acatg tcgtggga gggacccagt chr4:74069782-74069862 51 4.62e-04 taccagcact ttgggagg cacaggcggg chr2:38585542-38585622 59 4.62e-04 tcccagcact ttgggagg ccaaggcggg chr12:28321981-28322061 61 4.62e-04 tcccagcact ttgggagg ccgaggtggg chr2:48583427-48583507 44 4.62e-04 tcccagctac ttgggagg ctgaggcaag chr3:152029666-152029746 70 4.62e-04 tcccagcact ttgggagg ccg chr11:97819986-97820066 16 4.62e-04 ttgttactct ttgggagg actgatggtt chr1:191815053-191815133 28 4.89e-04 tttgtgtttt ttggtaga gacggggttt chr12:33738425-33738505 15 4.89e-04 ttttgtattt ttagtgga gacggggttt chr8:100180534-100180614 58 4.89e-04 CTGAGTACAG TTGGTAGA TAGTGTCTGT chr12:70656225-70656305 10 4.89e-04 ttgtatttt ttagtgga gacggggttt chr5:171392872-171392952 23 5.34e-04 ggtggttgac tcatgggg gtagacgtcc chr6:4844466-4844546 64 5.34e-04 ggtggcgctg tcaagaga gcatcagct chr11:58536985-58537065 38 5.34e-04 ggtaattgat tcatgggg gtggtttccc chr7:14087715-14087795 43 5.34e-04 ggtgattgga tcatgggg actaacttcc chr16:50312326-50312406 26 6.07e-04 tcttttttat ttgtggga gctctttaca chr3:171752963-171753043 64 6.07e-04 catgttcagt tcattgga agggaggtc chr21:30694447-30694527 61 6.07e-04 gacgtggcaa ttgtggga gctacaattc chr2:130986558-130986638 12 6.07e-04 TATTGTTGAT TTGTGGGA GCTCTTTGCA chr8:110433885-110433965 32 6.36e-04 cgaggctgag gcaggaga atggcgtgaa chr1:61685257-61685337 33 6.36e-04 ggaggctgag gcaggaga atggcgtgaa chr1:194824410-194824490 61 6.36e-04 ttcccctgag gcaggaga atgacgtgaa chr4:79721047-79721127 23 6.36e-04 TGGTTTTTCA TTAGTAGG ATAAATACAG chr21:31046795-31046875 57 6.51e-04 tccccatgtg tcgggggg gaacttggtg chr2:48581498-48581578 21 7.37e-04 ggtgggcgga tcacgagg tcaagaggtc chr7:106640008-106640088 16 7.37e-04 ggcgggcgga tcacgagg tcagaagatg chr1:165841087-165841167 18 7.37e-04 TAGAAAGAAT TTGTGAGG CAAATGAGAA chr5:38986181-38986261 66 7.37e-04 ggtgactgaa ttatgggg cggtttt chr3:87862801-87862881 71 7.37e-04 ggtgattgga ttatgggg gt chr11:97863862-97863942 22 7.37e-04 ggcaggcgga tcacgagg tcaggaaatc chr6:143515479-143515559 63 7.37e-04 cacgtagggg ttatgggg attacaattc chr2:15659060-15659140 46 8.07e-04 cacgtggaaa ttacggga gctacaagat chr3:151913961-151914041 67 8.65e-04 tcccagctac tcggtagg ccgagg chr6:69457763-69457843 31 8.65e-04 tccatatggc ttgggggg gcctcagaat chr4:186090372-186090452 59 9.21e-04 agggagggac ttggtgga aggtgattgg chr1:61763734-61763814 56 9.81e-04 ttcccatgtg tcaaggga gggaagtgat chr5:90578222-90578302 27 9.81e-04 tccccacgtg tcaaggga gggacctgta chr1:35852050-35852130 47 1.07e-03 caccagaaca gcagggga gaaatccacc chr2:87304078-87304158 43 1.21e-03 CTCATCGATC TTAAGGGA AAGGGGTACC chr1:54277422-54277502 36 1.29e-03 ccacctcctg gcaggagg cccaatcagc -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYAGGAGA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:68415777-68415857 1.5e-05 7_[+2]_65 chr8:28792202-28792282 1.5e-05 26_[+2]_46 chr2:11434065-11434145 1.5e-05 5_[+2]_67 chr13:79970196-79970276 1.5e-05 50_[+2]_22 chr21:22782237-22782317 1.5e-05 2_[+2]_70 chr21:15902413-15902493 1.5e-05 10_[+2]_62 chr3:172722889-172722969 1.5e-05 9_[+2]_63 chr4:166400892-166400972 1.5e-05 37_[+2]_35 chr8:106137608-106137688 1.5e-05 32_[+2]_40 chr9:37211764-37211844 1.5e-05 47_[+2]_25 chr8:38232305-38232385 1.5e-05 3_[+2]_69 chr3:84286734-84286814 1.5e-05 25_[+2]_47 chr7:103395800-103395880 1.5e-05 41_[+2]_31 chr2:158052676-158052756 1.5e-05 6_[+2]_66 chr18:33640147-33640227 1.5e-05 33_[+2]_39 chr7:135639450-135639530 1.5e-05 26_[+2]_46 chr12:28314128-28314208 1.5e-05 22_[+2]_50 chr4:74073637-74073717 1.5e-05 54_[+2]_18 chr6:49609667-49609747 1.5e-05 1_[+2]_71 chr12:23848651-23848731 1.5e-05 10_[+2]_62 chr2:58448077-58448157 1.5e-05 56_[+2]_16 chr2:48548438-48548518 1.5e-05 22_[+2]_50 chr6:13670803-13670883 1.5e-05 11_[+2]_61 chr10:22702212-22702292 1.5e-05 36_[+2]_36 chr4:74069213-74069293 1.5e-05 47_[+2]_25 chr6:49610677-49610757 1.5e-05 29_[+2]_43 chr12:62713988-62714068 4.4e-05 58_[+2]_14 chr2:24707612-24707692 4.4e-05 72_[+2] chr1:109067543-109067623 4.4e-05 5_[+2]_67 chr1:28133394-28133474 4.4e-05 20_[+2]_52 chr6:138177366-138177446 4.4e-05 65_[+2]_7 chr3:170515553-170515633 4.4e-05 24_[+2]_48 chr5:75814257-75814337 4.4e-05 8_[+2]_64 chr7:7175734-7175814 4.4e-05 23_[+2]_49 chr2:69953258-69953338 4.4e-05 59_[+2]_13 chr7:106145251-106145331 4.4e-05 30_[+2]_42 chr15:96308542-96308622 4.4e-05 11_[+2]_61 chr4:80109523-80109603 7.5e-05 2_[+2]_70 chr1:144685427-144685507 7.5e-05 36_[+2]_36 chr6:68719104-68719184 7.5e-05 57_[+2]_15 chr1:114260318-114260398 0.00018 72_[+2] chr21:38801872-38801952 0.00018 10_[+2]_62 chr1:145095684-145095764 0.0002 29_[+2]_43 chr11:16281701-16281781 0.0002 24_[+2]_48 chr11:124102569-12410264 0.0002 16_[+2]_56 chr11:5177713-5177793 0.0002 25_[+2]_47 chr3:135856559-135856639 0.0002 3_[+2]_69 chr11:95475761-95475841 0.0002 24_[+2]_48 chr1:212214990-212215070 0.0002 41_[+2]_31 chr6:105409431-105409511 0.0002 23_[+2]_49 chr10:22700945-22701025 0.0002 12_[+2]_60 chr11:97784837-97784917 0.0002 4_[+2]_68 chr10:11589713-11589793 0.0002 5_[+2]_67 chr1:28388277-28388357 0.0002 12_[+2]_60 chr21:22546362-22546442 0.0002 53_[+2]_19 chr5:65447852-65447932 0.0002 [+2]_72 chr7:110957056-110957136 0.0002 27_[+2]_45 chr11:16411277-16411357 0.00023 23_[+2]_49 chr2:223801619-223801699 0.00029 29_[+2]_43 chr7:106417545-106417625 0.00029 48_[+2]_24 chr1:180597949-180598029 0.00029 47_[+2]_25 chr6:15723140-15723220 0.00029 40_[+2]_32 chr15:52295436-52295516 0.00029 11_[+2]_61 chr14:61401179-61401259 0.00029 67_[+2]_5 chr1:93968858-93968938 0.00029 71_[+2]_1 chr12:77173303-77173383 0.00029 54_[+2]_18 chr7:111043229-111043309 0.00029 42_[+2]_30 chr2:15683838-15683918 0.00029 61_[+2]_11 chr7:111073626-111073706 0.00029 18_[+2]_54 chr1:85660712-85660792 0.00032 21_[+2]_51 chr9:76590207-76590287 0.00032 31_[+2]_41 chr6:49708680-49708760 0.00032 24_[+2]_48 chr4:140626374-140626454 0.00032 63_[+2]_9 chr6:147858710-147858790 0.00032 70_[+2]_2 chr4:127484672-127484752 0.00032 71_[+2]_1 chr6:135388045-135388125 0.00038 31_[+2]_41 chr12:111008752-11100883 0.00041 13_[+2]_59 chr1:192075295-192075375 0.00042 26_[+2]_46 chr1:89997965-89998045 0.00042 50_[+2]_22 chr5:61888589-61888669 0.00042 26_[+2]_46 chr6:118918101-118918181 0.00042 5_[+2]_67 chr4:74069782-74069862 0.00046 50_[+2]_22 chr2:38585542-38585622 0.00046 58_[+2]_14 chr12:28321981-28322061 0.00046 60_[+2]_12 chr2:48583427-48583507 0.00046 43_[+2]_29 chr3:152029666-152029746 0.00046 69_[+2]_3 chr11:97819986-97820066 0.00046 15_[+2]_57 chr1:191815053-191815133 0.00049 27_[+2]_45 chr12:33738425-33738505 0.00049 14_[+2]_58 chr8:100180534-100180614 0.00049 57_[+2]_15 chr12:70656225-70656305 0.00049 9_[+2]_63 chr5:171392872-171392952 0.00053 22_[+2]_50 chr6:4844466-4844546 0.00053 63_[+2]_9 chr11:58536985-58537065 0.00053 37_[+2]_35 chr7:14087715-14087795 0.00053 42_[+2]_30 chr16:50312326-50312406 0.00061 25_[+2]_47 chr3:171752963-171753043 0.00061 63_[+2]_9 chr21:30694447-30694527 0.00061 60_[+2]_12 chr2:130986558-130986638 0.00061 11_[+2]_61 chr8:110433885-110433965 0.00064 31_[+2]_41 chr1:61685257-61685337 0.00064 32_[+2]_40 chr1:194824410-194824490 0.00064 60_[+2]_12 chr4:79721047-79721127 0.00064 22_[+2]_50 chr21:31046795-31046875 0.00065 56_[+2]_16 chr2:48581498-48581578 0.00074 20_[+2]_52 chr7:106640008-106640088 0.00074 15_[+2]_57 chr1:165841087-165841167 0.00074 17_[+2]_55 chr5:38986181-38986261 0.00074 65_[+2]_7 chr3:87862801-87862881 0.00074 70_[+2]_2 chr11:97863862-97863942 0.00074 21_[+2]_51 chr6:143515479-143515559 0.00074 62_[+2]_10 chr2:15659060-15659140 0.00081 45_[+2]_27 chr3:151913961-151914041 0.00086 66_[+2]_6 chr6:69457763-69457843 0.00086 30_[+2]_42 chr4:186090372-186090452 0.00092 58_[+2]_14 chr1:61763734-61763814 0.00098 55_[+2]_17 chr5:90578222-90578302 0.00098 26_[+2]_46 chr1:35852050-35852130 0.0011 46_[+2]_26 chr2:87304078-87304158 0.0012 42_[+2]_30 chr1:54277422-54277502 0.0013 35_[+2]_37 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYAGGAGA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TYAGGAGA width=8 seqs=120 chr4:68415777-68415857 ( 8) TCAGGAGA 1 chr8:28792202-28792282 ( 27) TCAGGAGA 1 chr2:11434065-11434145 ( 6) TCAGGAGA 1 chr13:79970196-79970276 ( 51) TCAGGAGA 1 chr21:22782237-22782317 ( 3) TCAGGAGA 1 chr21:15902413-15902493 ( 11) TCAGGAGA 1 chr3:172722889-172722969 ( 10) TCAGGAGA 1 chr4:166400892-166400972 ( 38) TCAGGAGA 1 chr8:106137608-106137688 ( 33) TCAGGAGA 1 chr9:37211764-37211844 ( 48) TCAGGAGA 1 chr8:38232305-38232385 ( 4) TCAGGAGA 1 chr3:84286734-84286814 ( 26) TCAGGAGA 1 chr7:103395800-103395880 ( 42) TCAGGAGA 1 chr2:158052676-158052756 ( 7) TCAGGAGA 1 chr18:33640147-33640227 ( 34) TCAGGAGA 1 chr7:135639450-135639530 ( 27) TCAGGAGA 1 chr12:28314128-28314208 ( 23) TCAGGAGA 1 chr4:74073637-74073717 ( 55) TCAGGAGA 1 chr6:49609667-49609747 ( 2) TCAGGAGA 1 chr12:23848651-23848731 ( 11) TCAGGAGA 1 chr2:58448077-58448157 ( 57) TCAGGAGA 1 chr2:48548438-48548518 ( 23) TCAGGAGA 1 chr6:13670803-13670883 ( 12) TCAGGAGA 1 chr10:22702212-22702292 ( 37) TCAGGAGA 1 chr4:74069213-74069293 ( 48) TCAGGAGA 1 chr6:49610677-49610757 ( 30) TCAGGAGA 1 chr12:62713988-62714068 ( 59) TCATGAGA 1 chr2:24707612-24707692 ( 73) TCATGAGA 1 chr1:109067543-109067623 ( 6) TCATGAGA 1 chr1:28133394-28133474 ( 21) TCATGAGA 1 chr6:138177366-138177446 ( 66) TCATGAGA 1 chr3:170515553-170515633 ( 25) TCATGAGA 1 chr5:75814257-75814337 ( 9) TCATGAGA 1 chr7:7175734-7175814 ( 24) TCATGAGA 1 chr2:69953258-69953338 ( 60) TCATGAGA 1 chr7:106145251-106145331 ( 31) TCATGAGA 1 chr15:96308542-96308622 ( 12) TCATGAGA 1 chr4:80109523-80109603 ( 3) TCGGGAGA 1 chr1:144685427-144685507 ( 37) TCGGGAGA 1 chr6:68719104-68719184 ( 58) TCGGGAGA 1 chr1:114260318-114260398 ( 73) TCGTGAGA 1 chr21:38801872-38801952 ( 11) TCGTGAGA 1 chr1:145095684-145095764 ( 30) TTAGTAGA 1 chr11:16281701-16281781 ( 25) TTAGTAGA 1 chr11:124102569-12410264 ( 17) TTAGTAGA 1 chr11:5177713-5177793 ( 26) TTAGTAGA 1 chr3:135856559-135856639 ( 4) TTAGTAGA 1 chr11:95475761-95475841 ( 25) TTAGTAGA 1 chr1:212214990-212215070 ( 42) TTAGTAGA 1 chr6:105409431-105409511 ( 24) TTAGTAGA 1 chr10:22700945-22701025 ( 13) TTAGTAGA 1 chr11:97784837-97784917 ( 5) TTAGTAGA 1 chr10:11589713-11589793 ( 6) TTAGTAGA 1 chr1:28388277-28388357 ( 13) TTAGTAGA 1 chr21:22546362-22546442 ( 54) TTAGTAGA 1 chr5:65447852-65447932 ( 1) TTAGTAGA 1 chr7:110957056-110957136 ( 28) TTAGTAGA 1 chr11:16411277-16411357 ( 24) TCGGGGGA 1 chr2:223801619-223801699 ( 30) TCACGAGA 1 chr7:106417545-106417625 ( 49) TTGTGAGA 1 chr1:180597949-180598029 ( 48) TTATGGGA 1 chr6:15723140-15723220 ( 41) TTATGGGA 1 chr15:52295436-52295516 ( 12) TCACGAGA 1 chr14:61401179-61401259 ( 68) TCACGAGA 1 chr1:93968858-93968938 ( 72) TTATGGGA 1 chr12:77173303-77173383 ( 55) TTATGGGA 1 chr7:111043229-111043309 ( 43) TCACGAGA 1 chr2:15683838-15683918 ( 62) TTATGGGA 1 chr7:111073626-111073706 ( 19) TTATGGGA 1 chr1:85660712-85660792 ( 22) TCGGGAGG 1 chr9:76590207-76590287 ( 32) TCGGGAGG 1 chr6:49708680-49708760 ( 25) TCGGGAGG 1 chr4:140626374-140626454 ( 64) TCAGGGGG 1 chr6:147858710-147858790 ( 71) TCGGGAGG 1 chr4:127484672-127484752 ( 72) TCGGGAGG 1 chr6:135388045-135388125 ( 32) TTGGGGGA 1 chr12:111008752-11100883 ( 14) TTACGAGA 1 chr1:192075295-192075375 ( 27) TCGTGGGA 1 chr1:89997965-89998045 ( 51) TCGTGGGA 1 chr5:61888589-61888669 ( 27) TCGTGGGA 1 chr6:118918101-118918181 ( 6) TCGTGGGA 1 chr4:74069782-74069862 ( 51) TTGGGAGG 1 chr2:38585542-38585622 ( 59) TTGGGAGG 1 chr12:28321981-28322061 ( 61) TTGGGAGG 1 chr2:48583427-48583507 ( 44) TTGGGAGG 1 chr3:152029666-152029746 ( 70) TTGGGAGG 1 chr11:97819986-97820066 ( 16) TTGGGAGG 1 chr1:191815053-191815133 ( 28) TTGGTAGA 1 chr12:33738425-33738505 ( 15) TTAGTGGA 1 chr8:100180534-100180614 ( 58) TTGGTAGA 1 chr12:70656225-70656305 ( 10) TTAGTGGA 1 chr5:171392872-171392952 ( 23) TCATGGGG 1 chr6:4844466-4844546 ( 64) TCAAGAGA 1 chr11:58536985-58537065 ( 38) TCATGGGG 1 chr7:14087715-14087795 ( 43) TCATGGGG 1 chr16:50312326-50312406 ( 26) TTGTGGGA 1 chr3:171752963-171753043 ( 64) TCATTGGA 1 chr21:30694447-30694527 ( 61) TTGTGGGA 1 chr2:130986558-130986638 ( 12) TTGTGGGA 1 chr8:110433885-110433965 ( 32) GCAGGAGA 1 chr1:61685257-61685337 ( 33) GCAGGAGA 1 chr1:194824410-194824490 ( 61) GCAGGAGA 1 chr4:79721047-79721127 ( 23) TTAGTAGG 1 chr21:31046795-31046875 ( 57) TCGGGGGG 1 chr2:48581498-48581578 ( 21) TCACGAGG 1 chr7:106640008-106640088 ( 16) TCACGAGG 1 chr1:165841087-165841167 ( 18) TTGTGAGG 1 chr5:38986181-38986261 ( 66) TTATGGGG 1 chr3:87862801-87862881 ( 71) TTATGGGG 1 chr11:97863862-97863942 ( 22) TCACGAGG 1 chr6:143515479-143515559 ( 63) TTATGGGG 1 chr2:15659060-15659140 ( 46) TTACGGGA 1 chr3:151913961-151914041 ( 67) TCGGTAGG 1 chr6:69457763-69457843 ( 31) TTGGGGGG 1 chr4:186090372-186090452 ( 59) TTGGTGGA 1 chr1:61763734-61763814 ( 56) TCAAGGGA 1 chr5:90578222-90578302 ( 27) TCAAGGGA 1 chr1:35852050-35852130 ( 47) GCAGGGGA 1 chr2:87304078-87304158 ( 43) TTAAGGGA 1 chr1:54277422-54277502 ( 36) GCAGGAGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYAGGAGA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 7.91699 E= 6.9e-051 -1355 -1355 -258 200 -1355 125 -1355 67 152 -1355 14 -1355 -292 -179 127 28 -1355 -1355 170 -33 152 -1355 14 -1355 -1355 -1355 200 -1355 162 -1355 -15 -1355 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYAGGAGA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 120 E= 6.9e-051 0.000000 0.000000 0.041667 0.958333 0.000000 0.616667 0.000000 0.383333 0.725000 0.000000 0.275000 0.000000 0.033333 0.075000 0.600000 0.291667 0.000000 0.000000 0.808333 0.191667 0.725000 0.000000 0.275000 0.000000 0.000000 0.000000 1.000000 0.000000 0.775000 0.000000 0.225000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYAGGAGA MEME-2 regular expression -------------------------------------------------------------------------------- T[CT][AG][GT]G[AG]G[AG] -------------------------------------------------------------------------------- Time 8.64 secs. ******************************************************************************** ******************************************************************************** MOTIF TCTMCTRA MEME-3 width = 8 sites = 75 llr = 603 E-value = 2.1e-037 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCTMCTRA MEME-3 Description -------------------------------------------------------------------------------- Simplified A :::4::59 pos.-specific C 2a:5a2:1 probability G ::::::4: matrix T 8:a1:8:: bits 2.1 * 1.9 ** * 1.6 ** * 1.4 ** ** * Relative 1.2 *** ** * Entropy 1.0 *** ** * (11.6 bits) 0.8 *** **** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCTCCTAA consensus C A G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTMCTRA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:191980796-191980876 57 1.53e-05 atggtctcga tctcctaa ctcgtgatcc chr4:80109523-80109603 47 4.52e-05 aaaccccatc tctactaa aaatacaaaa chr4:68415777-68415857 52 4.52e-05 aaaccctgtc tctactaa aaaatacaaa chr8:28792202-28792282 71 4.52e-05 aaaccccatc tctactaa aa chr2:43954327-43954407 57 4.52e-05 aaactctgtc tctactaa aatacaaaaa chr2:11434065-11434145 49 4.52e-05 gaaacttgtc tctactaa aaatacaaaa chr3:151913961-151914041 7 4.52e-05 tctgcc tctactaa aaatacaaaa chr21:22782237-22782317 47 4.52e-05 aaaccccgtc tctactaa aaatacaaaa chr3:172722889-172722969 54 4.52e-05 aaaccctgtc tctactaa aacacacaaa chr2:48581498-48581578 73 4.52e-05 aaaccccatc tctactaa chr1:191815053-191815133 72 4.52e-05 atggtcttga tctcctga c chr2:185071516-185071596 32 4.52e-05 atggtcttga tctcctga cctcgtgatc chr8:38232305-38232385 48 4.52e-05 aaaacccatc tctactaa aaatacaaaa chr3:84286734-84286814 70 4.52e-05 aaaccccgtc tctactaa aaa chr1:85663550-85663630 11 4.52e-05 atggtctcga tctcctga cctcgtgatc chr3:37271992-37272072 6 4.52e-05 ctcga tctcctga cctcgtgatc chr12:33738425-33738505 59 4.52e-05 atggtctcga tctcctga tctcgtgatc chr6:129998337-129998417 32 4.52e-05 aaaccccgtc tctactaa aattacaaaa chr11:124102569-12410264 61 4.52e-05 atggtctcga tctcctga cctcgtgatc chr3:135856559-135856639 48 4.52e-05 acgatctcga tctcctga cctcgtgatc chr2:158052676-158052756 51 4.52e-05 aaaccccctc tctactaa aaaaaaaaat chr14:61401179-61401259 47 4.52e-05 tccatgctgt tctcctga gagtgaataa chr6:138043676-138043756 18 4.52e-05 atggtctcga tctcctga cctcgtgatc chr12:96730423-96730503 31 4.52e-05 CCTAatgttt tctactaa cgtatcctcc chr11:97784837-97784917 49 4.52e-05 atgatctcga tctcctga tctcgtgatc chr12:28314128-28314208 67 4.52e-05 aaaccccgtt tctactaa aacata chr5:56544460-56544540 25 4.52e-05 atggtctcga tctcctga cctcgtgatc chr10:11589713-11589793 50 4.52e-05 atggtctcga tctcctga cctcgtgatc chr1:28388277-28388357 57 4.52e-05 atgatctcga tctcctga cctcgtgatc chr6:49609667-49609747 46 4.52e-05 aaaccctgtc tctactaa aaatacaaaa chr6:147858710-147858790 9 4.52e-05 accccgtc tctactaa aaatacaaaa chr12:23848651-23848731 55 4.52e-05 aaaccccgtc tctactaa aaatacaaaa chr7:123340017-123340097 44 4.52e-05 aaaccccgtc tctactaa caatacaaaa chr7:13121711-13121791 20 4.52e-05 aaacaccgtc tctactaa aaatacaaaa chr12:33813003-33813083 44 4.52e-05 aacccccgtc tctactaa aaacacaaaa chr2:48548438-48548518 66 4.52e-05 aaaccccgtc tctactaa aaataca chr5:65447852-65447932 45 4.52e-05 atagtctcga tctcctga cctcgtgatc chr12:70656225-70656305 54 4.52e-05 atggtctcga tctcctga cctcgtgatc chr7:110957056-110957136 72 4.52e-05 atggtctcga tctcctga c chr21:15919225-15919305 29 4.52e-05 atggtctcga tctcctga tctcgtgatc chr11:16411277-16411357 68 4.52e-05 aaaccccgtc tctactaa aaata chr2:170781334-170781414 41 5.98e-05 aaaccttgtc tctactga atatacaaaa chr6:119582397-119582477 1 7.63e-05 . cctcctaa agtgctggga chr6:15723140-15723220 21 7.63e-05 ccactgggtc cctcctaa gacatgtggg chr6:105410994-105411074 47 1.25e-04 cctgcttcag cctcctga gtagctggga chr21:15902413-15902493 55 1.25e-04 aaaccccatc cctactaa aaatacaaaa chr1:185235298-185235378 17 1.25e-04 cctgcctcag cctcctga atagctggga chr21:22576328-22576408 62 1.39e-04 TCAACAAGTG TCTTCTAA CATACCTGTT chr9:71369267-71369347 42 1.87e-04 atggtctcaa tctcccga cctcgtgatt chr7:106640008-106640088 68 1.87e-04 aaacccggtc tctaccaa aaata chr15:58390510-58390590 48 1.87e-04 cctgcctcag tctcccga gtagctggga chr6:13670803-13670883 56 1.87e-04 aaaccccgtc tctaccaa aaatacaaaa chr5:12579072-12579152 17 2.01e-04 atgatctcga tcttctga cctcgtgatc chr9:37236575-37236655 40 2.01e-04 atgatctcga tcttctga cctcgtgatc chr4:48769304-48769384 13 2.01e-04 aacagccaga tcttctga gaactcgctc chr2:15683838-15683918 28 2.33e-04 gattcaatca tctcctac tgggtccctc chr7:120687849-120687929 22 2.63e-04 ttcacgccat tctcctgc ctcagcctcc chr4:151224807-151224887 23 2.63e-04 ttcacgccat tctcctgc tcagcctccc chr7:22380964-22381044 73 2.81e-04 ccacccggcc cctcccaa chr1:180597949-180598029 28 2.81e-04 ccaccaggtc cctcccaa gacatatggg chr20:46233813-46233893 51 2.81e-04 cccgccttgg cctcccaa agtgctggga chr3:169486538-169486618 32 2.81e-04 ccctgctcgg cctcccaa agtgctagga chr1:52754053-52754133 38 2.81e-04 tcctcctcag cctcccaa ggggctggga chr16:53249028-53249108 54 2.81e-04 cctgcctcgg cctcccaa agtgctggga chr2:158061851-158061931 71 2.81e-04 cccgcctccg cctcccaa ag chr18:34479399-34479479 37 3.12e-04 AATCTGACAC TCTACTGC CACCTGGTGA chr2:87304078-87304158 29 3.62e-04 ATTTATTTCG TCTCCTCA TCGATCTTAA chr7:12751335-12751415 62 3.62e-04 cccgcctcag cctcccga gtagctggga chr15:50606587-50606667 17 3.62e-04 atggtctcga tctcctca cctcgtgatc chr6:139825411-139825491 14 3.62e-04 cccatctcag cctcccga gtagctggga chr14:61314930-61315010 21 3.92e-04 cgttccacta ccttctga cttctatggt chr8:100180534-100180614 44 3.92e-04 CACCCAATTT CCTTCTGA GTACAGTTGG chr7:7175734-7175814 67 4.57e-04 gattcaatta cctcctac cgggtc chr2:100078676-100078756 15 5.07e-04 gtttacaagt cctacTAC CCATGTGTGG chr2:15659060-15659140 12 5.07e-04 gattcaatca tctcccac caggtccctc -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTMCTRA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:191980796-191980876 1.5e-05 56_[+3]_16 chr4:80109523-80109603 4.5e-05 46_[+3]_26 chr4:68415777-68415857 4.5e-05 51_[+3]_21 chr8:28792202-28792282 4.5e-05 70_[+3]_2 chr2:43954327-43954407 4.5e-05 56_[+3]_16 chr2:11434065-11434145 4.5e-05 48_[+3]_24 chr3:151913961-151914041 4.5e-05 6_[+3]_66 chr21:22782237-22782317 4.5e-05 46_[+3]_26 chr3:172722889-172722969 4.5e-05 53_[+3]_19 chr2:48581498-48581578 4.5e-05 72_[+3] chr1:191815053-191815133 4.5e-05 71_[+3]_1 chr2:185071516-185071596 4.5e-05 31_[+3]_41 chr8:38232305-38232385 4.5e-05 47_[+3]_25 chr3:84286734-84286814 4.5e-05 69_[+3]_3 chr1:85663550-85663630 4.5e-05 10_[+3]_62 chr3:37271992-37272072 4.5e-05 5_[+3]_67 chr12:33738425-33738505 4.5e-05 58_[+3]_14 chr6:129998337-129998417 4.5e-05 31_[+3]_41 chr11:124102569-12410264 4.5e-05 60_[+3]_12 chr3:135856559-135856639 4.5e-05 47_[+3]_25 chr2:158052676-158052756 4.5e-05 50_[+3]_22 chr14:61401179-61401259 4.5e-05 46_[+3]_26 chr6:138043676-138043756 4.5e-05 17_[+3]_55 chr12:96730423-96730503 4.5e-05 30_[+3]_42 chr11:97784837-97784917 4.5e-05 48_[+3]_24 chr12:28314128-28314208 4.5e-05 66_[+3]_6 chr5:56544460-56544540 4.5e-05 24_[+3]_48 chr10:11589713-11589793 4.5e-05 49_[+3]_23 chr1:28388277-28388357 4.5e-05 56_[+3]_16 chr6:49609667-49609747 4.5e-05 45_[+3]_27 chr6:147858710-147858790 4.5e-05 8_[+3]_64 chr12:23848651-23848731 4.5e-05 54_[+3]_18 chr7:123340017-123340097 4.5e-05 43_[+3]_29 chr7:13121711-13121791 4.5e-05 19_[+3]_53 chr12:33813003-33813083 4.5e-05 43_[+3]_29 chr2:48548438-48548518 4.5e-05 65_[+3]_7 chr5:65447852-65447932 4.5e-05 44_[+3]_28 chr12:70656225-70656305 4.5e-05 53_[+3]_19 chr7:110957056-110957136 4.5e-05 71_[+3]_1 chr21:15919225-15919305 4.5e-05 28_[+3]_44 chr11:16411277-16411357 4.5e-05 67_[+3]_5 chr2:170781334-170781414 6e-05 40_[+3]_32 chr6:119582397-119582477 7.6e-05 [+3]_72 chr6:15723140-15723220 7.6e-05 20_[+3]_52 chr6:105410994-105411074 0.00013 46_[+3]_26 chr21:15902413-15902493 0.00013 54_[+3]_18 chr1:185235298-185235378 0.00013 16_[+3]_56 chr21:22576328-22576408 0.00014 61_[+3]_11 chr9:71369267-71369347 0.00019 41_[+3]_31 chr7:106640008-106640088 0.00019 67_[+3]_5 chr15:58390510-58390590 0.00019 47_[+3]_25 chr6:13670803-13670883 0.00019 55_[+3]_17 chr5:12579072-12579152 0.0002 16_[+3]_56 chr9:37236575-37236655 0.0002 39_[+3]_33 chr4:48769304-48769384 0.0002 12_[+3]_60 chr2:15683838-15683918 0.00023 27_[+3]_45 chr7:120687849-120687929 0.00026 21_[+3]_51 chr4:151224807-151224887 0.00026 22_[+3]_50 chr7:22380964-22381044 0.00028 72_[+3] chr1:180597949-180598029 0.00028 27_[+3]_45 chr20:46233813-46233893 0.00028 50_[+3]_22 chr3:169486538-169486618 0.00028 31_[+3]_41 chr1:52754053-52754133 0.00028 37_[+3]_35 chr16:53249028-53249108 0.00028 53_[+3]_19 chr2:158061851-158061931 0.00028 70_[+3]_2 chr18:34479399-34479479 0.00031 36_[+3]_36 chr2:87304078-87304158 0.00036 28_[+3]_44 chr7:12751335-12751415 0.00036 61_[+3]_11 chr15:50606587-50606667 0.00036 16_[+3]_56 chr6:139825411-139825491 0.00036 13_[+3]_59 chr14:61314930-61315010 0.00039 20_[+3]_52 chr8:100180534-100180614 0.00039 43_[+3]_29 chr7:7175734-7175814 0.00046 66_[+3]_6 chr2:100078676-100078756 0.00051 14_[+3]_58 chr2:15659060-15659140 0.00051 11_[+3]_61 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTMCTRA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCTMCTRA width=8 seqs=75 chr1:191980796-191980876 ( 57) TCTCCTAA 1 chr4:80109523-80109603 ( 47) TCTACTAA 1 chr4:68415777-68415857 ( 52) TCTACTAA 1 chr8:28792202-28792282 ( 71) TCTACTAA 1 chr2:43954327-43954407 ( 57) TCTACTAA 1 chr2:11434065-11434145 ( 49) TCTACTAA 1 chr3:151913961-151914041 ( 7) TCTACTAA 1 chr21:22782237-22782317 ( 47) TCTACTAA 1 chr3:172722889-172722969 ( 54) TCTACTAA 1 chr2:48581498-48581578 ( 73) TCTACTAA 1 chr1:191815053-191815133 ( 72) TCTCCTGA 1 chr2:185071516-185071596 ( 32) TCTCCTGA 1 chr8:38232305-38232385 ( 48) TCTACTAA 1 chr3:84286734-84286814 ( 70) TCTACTAA 1 chr1:85663550-85663630 ( 11) TCTCCTGA 1 chr3:37271992-37272072 ( 6) TCTCCTGA 1 chr12:33738425-33738505 ( 59) TCTCCTGA 1 chr6:129998337-129998417 ( 32) TCTACTAA 1 chr11:124102569-12410264 ( 61) TCTCCTGA 1 chr3:135856559-135856639 ( 48) TCTCCTGA 1 chr2:158052676-158052756 ( 51) TCTACTAA 1 chr14:61401179-61401259 ( 47) TCTCCTGA 1 chr6:138043676-138043756 ( 18) TCTCCTGA 1 chr12:96730423-96730503 ( 31) TCTACTAA 1 chr11:97784837-97784917 ( 49) TCTCCTGA 1 chr12:28314128-28314208 ( 67) TCTACTAA 1 chr5:56544460-56544540 ( 25) TCTCCTGA 1 chr10:11589713-11589793 ( 50) TCTCCTGA 1 chr1:28388277-28388357 ( 57) TCTCCTGA 1 chr6:49609667-49609747 ( 46) TCTACTAA 1 chr6:147858710-147858790 ( 9) TCTACTAA 1 chr12:23848651-23848731 ( 55) TCTACTAA 1 chr7:123340017-123340097 ( 44) TCTACTAA 1 chr7:13121711-13121791 ( 20) TCTACTAA 1 chr12:33813003-33813083 ( 44) TCTACTAA 1 chr2:48548438-48548518 ( 66) TCTACTAA 1 chr5:65447852-65447932 ( 45) TCTCCTGA 1 chr12:70656225-70656305 ( 54) TCTCCTGA 1 chr7:110957056-110957136 ( 72) TCTCCTGA 1 chr21:15919225-15919305 ( 29) TCTCCTGA 1 chr11:16411277-16411357 ( 68) TCTACTAA 1 chr2:170781334-170781414 ( 41) TCTACTGA 1 chr6:119582397-119582477 ( 1) CCTCCTAA 1 chr6:15723140-15723220 ( 21) CCTCCTAA 1 chr6:105410994-105411074 ( 47) CCTCCTGA 1 chr21:15902413-15902493 ( 55) CCTACTAA 1 chr1:185235298-185235378 ( 17) CCTCCTGA 1 chr21:22576328-22576408 ( 62) TCTTCTAA 1 chr9:71369267-71369347 ( 42) TCTCCCGA 1 chr7:106640008-106640088 ( 68) TCTACCAA 1 chr15:58390510-58390590 ( 48) TCTCCCGA 1 chr6:13670803-13670883 ( 56) TCTACCAA 1 chr5:12579072-12579152 ( 17) TCTTCTGA 1 chr9:37236575-37236655 ( 40) TCTTCTGA 1 chr4:48769304-48769384 ( 13) TCTTCTGA 1 chr2:15683838-15683918 ( 28) TCTCCTAC 1 chr7:120687849-120687929 ( 22) TCTCCTGC 1 chr4:151224807-151224887 ( 23) TCTCCTGC 1 chr7:22380964-22381044 ( 73) CCTCCCAA 1 chr1:180597949-180598029 ( 28) CCTCCCAA 1 chr20:46233813-46233893 ( 51) CCTCCCAA 1 chr3:169486538-169486618 ( 32) CCTCCCAA 1 chr1:52754053-52754133 ( 38) CCTCCCAA 1 chr16:53249028-53249108 ( 54) CCTCCCAA 1 chr2:158061851-158061931 ( 71) CCTCCCAA 1 chr18:34479399-34479479 ( 37) TCTACTGC 1 chr2:87304078-87304158 ( 29) TCTCCTCA 1 chr7:12751335-12751415 ( 62) CCTCCCGA 1 chr15:50606587-50606667 ( 17) TCTCCTCA 1 chr6:139825411-139825491 ( 14) CCTCCCGA 1 chr14:61314930-61315010 ( 21) CCTTCTGA 1 chr8:100180534-100180614 ( 44) CCTTCTGA 1 chr7:7175734-7175814 ( 67) CCTCCTAC 1 chr2:100078676-100078756 ( 15) CCTACTAC 1 chr2:15659060-15659140 ( 12) TCTCCCAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTMCTRA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.10161 E= 2.1e-037 -1287 -11 -1287 166 -1287 195 -1287 -1287 -1287 -1287 -1287 206 62 104 -1287 -159 -1287 195 -1287 -1287 -1287 -47 -1287 176 112 -328 78 -1287 185 -147 -1287 -1287 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTMCTRA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 75 E= 2.1e-037 0.000000 0.240000 0.000000 0.760000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.386667 0.533333 0.000000 0.080000 0.000000 1.000000 0.000000 0.000000 0.000000 0.186667 0.000000 0.813333 0.546667 0.026667 0.426667 0.000000 0.906667 0.093333 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTMCTRA MEME-3 regular expression -------------------------------------------------------------------------------- [TC]CT[CA]CT[AG]A -------------------------------------------------------------------------------- Time 12.19 secs. ******************************************************************************** ******************************************************************************** MOTIF CTGGCTAA MEME-4 width = 8 sites = 45 llr = 420 E-value = 3.0e-032 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTGGCTAA MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::1:::aa pos.-specific C a2::a1:: probability G ::9a:::: matrix T :8:::9:: bits 2.1 * 1.9 * ** 1.6 * ** ** 1.4 ******** Relative 1.2 ******** Entropy 1.0 ******** (13.5 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTGGCTAA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGGCTAA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:80109523-80109603 22 1.52e-05 cgagaccatc ctggctaa cgcggtgaaa chr8:28792202-28792282 46 1.52e-05 cgagaccatc ctggctaa cacggtgaaa chr2:11434065-11434145 25 1.52e-05 cgagaccatc ctggctaa cacagtgaaa chr21:22782237-22782317 22 1.52e-05 cgagaccatc ctggctaa cacagtgaaa chr21:15902413-15902493 30 1.52e-05 ccagaccacc ctggctaa tacggtgaaa chr4:166400892-166400972 57 1.52e-05 cgagaccatc ctggctaa cacagtgaaa chr8:106137608-106137688 52 1.52e-05 cgagaccatc ctggctaa cacggtgaaa chr9:37211764-37211844 67 1.52e-05 cgagaccatc ctggctaa cacggt chr3:84286734-84286814 45 1.52e-05 cgagaccatc ctggctaa cacggtgaaa chr7:103395800-103395880 61 1.52e-05 cgagacaatc ctggctaa cacggtgaaa chr6:129998337-129998417 7 1.52e-05 accacc ctggctaa cacggtgaaa chr7:106640008-106640088 43 1.52e-05 ggagaccatc ctggctaa cacggtgaaa chr2:158052676-158052756 26 1.52e-05 cgagaccatt ctggctaa cacggtgaaa chr1:212214990-212215070 16 1.52e-05 gccaccacgc ctggctaa tttttttttt chr12:23848651-23848731 30 1.52e-05 cgagaccatc ctggctaa cacggtgaaa chr7:123340017-123340097 19 1.52e-05 cgagaccatc ctggctaa cacggtgaaa chr12:33813003-33813083 19 1.52e-05 caagaccatc ctggctaa cacggtgaac chr2:48548438-48548518 41 1.52e-05 tcgagaccgt ctggctaa cacggtgaaa chr6:13670803-13670883 31 1.52e-05 cgagaccatc ctggctaa cacggtgaaa chr11:97863862-97863942 49 1.52e-05 cgagaccatc ctggctaa cacggtgaaa chr10:22702212-22702292 56 1.52e-05 cgagaccgtc ctggctaa cacggtgaaa chr4:74069213-74069293 67 1.52e-05 cgagaccatc ctggctaa catggt chr1:145095684-145095764 7 3.16e-05 ccgcgc ccggctaa tttttttgtg chr1:191815053-191815133 7 3.16e-05 ctgtgc ccggctaa ttttttgtgt chr11:5177713-5177793 4 3.16e-05 agc ccggctaa ttttttgtat chr7:120687849-120687929 69 3.16e-05 agtcccacgc ccggctaa tttt chr5:43482084-43482164 20 3.16e-05 gccaccacgc ccggctaa tttcttgtat chr11:16411277-16411357 43 3.16e-05 cgagaccatc ccggctaa cacggtgaaa chr6:139825411-139825491 54 3.16e-05 gccaccacgc ccggctaa tttggttttt chr4:68415777-68415857 27 4.70e-05 cgagaccgtc ctagctaa catggtgaaa chr8:38232305-38232385 23 4.70e-05 cgagaccatc ctagctaa cacggtgaaa chr15:67539059-67539139 18 4.70e-05 cactctgtgt ctagctaa aggattgtaa chr6:105409431-105409511 4 4.70e-05 cgc ctagctaa ttttttgtat chr3:172722889-172722969 29 6.34e-05 cgagaccatc ctggccaa catggtgaaa chr2:48581498-48581578 48 6.34e-05 caagtccagc ctggccaa cagagtgaaa chr2:170781334-170781414 16 6.34e-05 cgagaccatc ctggccaa catggtgaaa chr7:120699923-120700003 54 6.34e-05 cctttctggg ctggccaa gaccggagcc chr6:49610677-49610757 60 6.34e-05 caagaccatt ctggccaa cacggtgaag chr11:16281701-16281781 4 9.16e-05 cac ttggctaa ttttttgtat chr1:32312247-32312327 11 9.16e-05 ATAATCTACC CTGGTTAA AGTGatccac chr12:28314128-28314208 42 9.16e-05 cgagaccatc ctggttaa cacggtgaaa chr6:49609667-49609747 21 9.16e-05 tgagaccatc ttggctaa cacggtgaaa chr11:95475761-95475841 4 1.08e-04 tgc ccagctaa tttttttgta chr7:106683103-106683183 70 1.57e-04 gctgagggag ctggctca ggc chr1:144685427-144685507 56 1.57e-04 cgagaccatc ctgcctaa cacggtgaaa -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGGCTAA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:80109523-80109603 1.5e-05 21_[+4]_51 chr8:28792202-28792282 1.5e-05 45_[+4]_27 chr2:11434065-11434145 1.5e-05 24_[+4]_48 chr21:22782237-22782317 1.5e-05 21_[+4]_51 chr21:15902413-15902493 1.5e-05 29_[+4]_43 chr4:166400892-166400972 1.5e-05 56_[+4]_16 chr8:106137608-106137688 1.5e-05 51_[+4]_21 chr9:37211764-37211844 1.5e-05 66_[+4]_6 chr3:84286734-84286814 1.5e-05 44_[+4]_28 chr7:103395800-103395880 1.5e-05 60_[+4]_12 chr6:129998337-129998417 1.5e-05 6_[+4]_66 chr7:106640008-106640088 1.5e-05 42_[+4]_30 chr2:158052676-158052756 1.5e-05 25_[+4]_47 chr1:212214990-212215070 1.5e-05 15_[+4]_57 chr12:23848651-23848731 1.5e-05 29_[+4]_43 chr7:123340017-123340097 1.5e-05 18_[+4]_54 chr12:33813003-33813083 1.5e-05 18_[+4]_54 chr2:48548438-48548518 1.5e-05 40_[+4]_32 chr6:13670803-13670883 1.5e-05 30_[+4]_42 chr11:97863862-97863942 1.5e-05 48_[+4]_24 chr10:22702212-22702292 1.5e-05 55_[+4]_17 chr4:74069213-74069293 1.5e-05 66_[+4]_6 chr1:145095684-145095764 3.2e-05 6_[+4]_66 chr1:191815053-191815133 3.2e-05 6_[+4]_66 chr11:5177713-5177793 3.2e-05 3_[+4]_69 chr7:120687849-120687929 3.2e-05 68_[+4]_4 chr5:43482084-43482164 3.2e-05 19_[+4]_53 chr11:16411277-16411357 3.2e-05 42_[+4]_30 chr6:139825411-139825491 3.2e-05 53_[+4]_19 chr4:68415777-68415857 4.7e-05 26_[+4]_46 chr8:38232305-38232385 4.7e-05 22_[+4]_50 chr15:67539059-67539139 4.7e-05 17_[+4]_55 chr6:105409431-105409511 4.7e-05 3_[+4]_69 chr3:172722889-172722969 6.3e-05 28_[+4]_44 chr2:48581498-48581578 6.3e-05 47_[+4]_25 chr2:170781334-170781414 6.3e-05 15_[+4]_57 chr7:120699923-120700003 6.3e-05 53_[+4]_19 chr6:49610677-49610757 6.3e-05 59_[+4]_13 chr11:16281701-16281781 9.2e-05 3_[+4]_69 chr1:32312247-32312327 9.2e-05 10_[+4]_62 chr12:28314128-28314208 9.2e-05 41_[+4]_31 chr6:49609667-49609747 9.2e-05 20_[+4]_52 chr11:95475761-95475841 0.00011 3_[+4]_69 chr7:106683103-106683183 0.00016 69_[+4]_3 chr1:144685427-144685507 0.00016 55_[+4]_17 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGGCTAA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTGGCTAA width=8 seqs=45 chr4:80109523-80109603 ( 22) CTGGCTAA 1 chr8:28792202-28792282 ( 46) CTGGCTAA 1 chr2:11434065-11434145 ( 25) CTGGCTAA 1 chr21:22782237-22782317 ( 22) CTGGCTAA 1 chr21:15902413-15902493 ( 30) CTGGCTAA 1 chr4:166400892-166400972 ( 57) CTGGCTAA 1 chr8:106137608-106137688 ( 52) CTGGCTAA 1 chr9:37211764-37211844 ( 67) CTGGCTAA 1 chr3:84286734-84286814 ( 45) CTGGCTAA 1 chr7:103395800-103395880 ( 61) CTGGCTAA 1 chr6:129998337-129998417 ( 7) CTGGCTAA 1 chr7:106640008-106640088 ( 43) CTGGCTAA 1 chr2:158052676-158052756 ( 26) CTGGCTAA 1 chr1:212214990-212215070 ( 16) CTGGCTAA 1 chr12:23848651-23848731 ( 30) CTGGCTAA 1 chr7:123340017-123340097 ( 19) CTGGCTAA 1 chr12:33813003-33813083 ( 19) CTGGCTAA 1 chr2:48548438-48548518 ( 41) CTGGCTAA 1 chr6:13670803-13670883 ( 31) CTGGCTAA 1 chr11:97863862-97863942 ( 49) CTGGCTAA 1 chr10:22702212-22702292 ( 56) CTGGCTAA 1 chr4:74069213-74069293 ( 67) CTGGCTAA 1 chr1:145095684-145095764 ( 7) CCGGCTAA 1 chr1:191815053-191815133 ( 7) CCGGCTAA 1 chr11:5177713-5177793 ( 4) CCGGCTAA 1 chr7:120687849-120687929 ( 69) CCGGCTAA 1 chr5:43482084-43482164 ( 20) CCGGCTAA 1 chr11:16411277-16411357 ( 43) CCGGCTAA 1 chr6:139825411-139825491 ( 54) CCGGCTAA 1 chr4:68415777-68415857 ( 27) CTAGCTAA 1 chr8:38232305-38232385 ( 23) CTAGCTAA 1 chr15:67539059-67539139 ( 18) CTAGCTAA 1 chr6:105409431-105409511 ( 4) CTAGCTAA 1 chr3:172722889-172722969 ( 29) CTGGCCAA 1 chr2:48581498-48581578 ( 48) CTGGCCAA 1 chr2:170781334-170781414 ( 16) CTGGCCAA 1 chr7:120699923-120700003 ( 54) CTGGCCAA 1 chr6:49610677-49610757 ( 60) CTGGCCAA 1 chr11:16281701-16281781 ( 4) TTGGCTAA 1 chr1:32312247-32312327 ( 11) CTGGTTAA 1 chr12:28314128-28314208 ( 42) CTGGTTAA 1 chr6:49609667-49609747 ( 21) TTGGCTAA 1 chr11:95475761-95475841 ( 4) CCAGCTAA 1 chr7:106683103-106683183 ( 70) CTGGCTCA 1 chr1:144685427-144685507 ( 56) CTGCCTAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGGCTAA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.23915 E= 3.0e-032 -1214 189 -1214 -243 -1214 -54 -1214 178 -118 -1214 183 -1214 -1214 -354 197 -1214 -1214 189 -1214 -243 -1214 -122 -1214 189 196 -354 -1214 -1214 199 -1214 -1214 -1214 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGGCTAA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 45 E= 3.0e-032 0.000000 0.955556 0.000000 0.044444 0.000000 0.177778 0.000000 0.822222 0.111111 0.000000 0.888889 0.000000 0.000000 0.022222 0.977778 0.000000 0.000000 0.955556 0.000000 0.044444 0.000000 0.111111 0.000000 0.888889 0.977778 0.022222 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGGCTAA MEME-4 regular expression -------------------------------------------------------------------------------- CTGGCTAA -------------------------------------------------------------------------------- Time 15.62 secs. ******************************************************************************** ******************************************************************************** MOTIF TGTAABCC MEME-5 width = 8 sites = 76 llr = 615 E-value = 1.9e-040 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGTAABCC MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::378::: pos.-specific C :::::3aa probability G :a::23:: matrix T a:73:4:: bits 2.1 ** 1.9 ** ** 1.6 ** ** 1.4 ** * ** Relative 1.2 *** * ** Entropy 1.0 ***** ** (11.7 bits) 0.8 ***** ** 0.6 ***** ** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGTAATCC consensus AT C sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTAABCC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr15:48989283-48989363 34 1.47e-05 catcttgaat tgtaatcc ccataatccc chr2:38585542-38585622 44 1.47e-05 ggctcacacc tgtaatcc cagcactttg chr2:62959547-62959627 14 1.47e-05 cgtgttcagt tgtaatcc ccaatttgga chr12:28321981-28322061 46 1.47e-05 ggctcacgcc tgtaatcc cagcactttg chr1:61763734-61763814 9 1.47e-05 tctcgaat tgtaatcc ccacatgtcg chr4:186090372-186090452 31 1.47e-05 catctcgaat tgtaatcc ccacgtatgg chr2:48583427-48583507 29 1.47e-05 ggtgcacacc tgtaatcc cagctacttg chr4:74073637-74073717 10 1.47e-05 gctcacgcc tgtaatcc cagcactttg chr6:68719104-68719184 13 1.47e-05 ggctcaagcc tgtaatcc cagcactttg chr3:152029666-152029746 1 1.47e-05 . TGTAATCC TGAACTCTTA chr5:90578222-90578302 41 1.47e-05 gggagggacc tgtaatcc ccatgtatcg chr2:58448077-58448157 12 1.47e-05 ggctcacgcc tgtaatcc cagcactttg chr21:31046795-31046875 42 1.47e-05 tatcccgaat tgtaatcc ccatgtgtcg chr4:74069213-74069293 3 1.47e-05 cc tgtaatcc cagcactttg chr6:135388045-135388125 18 1.47e-05 catgttgaat tgtaatcc ccaatgttgg chr4:80920325-80920405 27 1.47e-05 catctcgaat tgtaatcc ccataatccc chr10:11589713-11589793 29 5.97e-05 ggtgtcaccg tgttatcc aggatggtct chr1:145095684-145095764 53 1.05e-04 ggtttcacca tgttagcc aggatggtct chr9:71369267-71369347 21 1.05e-04 ggtttcaccg tgttagcc aggatggtct chr11:16281701-16281781 48 1.05e-04 ggtttcacca tgttagcc acgatggtct chr1:191815053-191815133 51 1.05e-04 ggtttcaccg tgttagcc aggatggtct chr2:185071516-185071596 11 1.05e-04 ggttttttcg tgttagcc aggatggtct chr12:33738425-33738505 38 1.05e-04 ggtttcaccg tgttagcc aggatggtct chr11:124102569-12410264 40 1.05e-04 ggtttcactg tgttagcc aggatggtct chr11:5177713-5177793 49 1.05e-04 ggtttcactg tgttagcc aggatggtct chr3:135856559-135856639 27 1.05e-04 ggtttcaccg tgttagcc aggacgatct chr11:95475761-95475841 48 1.05e-04 ggtttcaccg tgttagcc agtatgttct chr1:212214990-212215070 65 1.05e-04 ggtttcaccg tgttagcc aggatggt chr16:53249028-53249108 3 1.05e-04 cg tgttagcc acgatggtct chr2:158061851-158061931 20 1.05e-04 ggtttcaccg tgttagcc aggattgtct chr10:22700945-22701025 36 1.05e-04 ggtttcaccg tgttagcc aggttggtct chr5:43482084-43482164 64 1.05e-04 gtttcacccg tgttagcc aggatggtc chr9:37236575-37236655 19 1.05e-04 ggtttcaccg tgttagcc aggatgatct chr1:28388277-28388357 36 1.05e-04 ggtttcaccg tgttagcc aggatgatct chr5:65447852-65447932 24 1.05e-04 ggtttcaccg tgttagcc aggatagtct chr12:70656225-70656305 33 1.05e-04 ggtttcaccg tgttagcc acgatggtct chr21:15919225-15919305 8 1.05e-04 ttcacca tgttagcc aagatggtct chr4:80109523-80109603 35 1.37e-04 gctaacgcgg tgaaaccc catctctact chr4:68415777-68415857 40 1.37e-04 gctaacatgg tgaaaccc tgtctctact chr8:28792202-28792282 59 1.37e-04 gctaacacgg tgaaaccc catctctact chr21:22782237-22782317 35 1.37e-04 gctaacacag tgaaaccc cgtctctact chr21:15902413-15902493 43 1.37e-04 gctaatacgg tgaaaccc catccctact chr3:172722889-172722969 42 1.37e-04 gccaacatgg tgaaaccc tgtctctact chr2:48581498-48581578 61 1.37e-04 gccaacagag tgaaaccc catctctact chr3:84286734-84286814 58 1.37e-04 gctaacacgg tgaaaccc cgtctctact chr6:129998337-129998417 20 1.37e-04 gctaacacgg tgaaaccc cgtctctact chr7:106640008-106640088 56 1.37e-04 gctaacacgg tgaaaccc ggtctctacc chr2:158052676-158052756 39 1.37e-04 gctaacacgg tgaaaccc cctctctact chr1:144685427-144685507 69 1.37e-04 cctaacacgg tgaaaccc cgtc chr7:135639450-135639530 59 1.37e-04 gctaacacgg tgaaaccc cgtctcaact chr12:28314128-28314208 55 1.37e-04 gttaacacgg tgaaaccc cgtttctact chr6:49609667-49609747 34 1.37e-04 gctaacacgg tgaaaccc tgtctctact chr12:23848651-23848731 43 1.37e-04 gctaacacgg tgaaaccc cgtctctact chr7:123340017-123340097 32 1.37e-04 gctaacacgg tgaaaccc cgtctctact chr17:57860336-57860416 39 1.37e-04 gctgacatgg tgaaaccc cgtctccact chr2:48548438-48548518 54 1.37e-04 gctaacacgg tgaaaccc cgtctctact chr6:13670803-13670883 44 1.37e-04 gctaacacgg tgaaaccc cgtctctacc chr11:97863862-97863942 62 1.37e-04 gctaacacgg tgaaaccc catctccact chr10:22702212-22702292 69 1.37e-04 gctaacacgg tgaaaccc cgtc chr11:16411277-16411357 56 1.37e-04 gctaacacgg tgaaaccc cgtctctact chr1:85660712-85660792 7 1.66e-04 ggcgcc tgtagtcc cagctactcg chr3:151913961-151914041 52 1.66e-04 ggcgggcttc tgtagtcc cagctactcg chr6:158247348-158247428 60 1.66e-04 ggcgggcgcc tgtagtcc cagctactcg chr21:16096553-16096633 45 1.66e-04 ggcacacacc tgtagtcc cagctactcg chr6:49708680-49708760 10 1.66e-04 gcgagagcc tgtagtcc cagctactcg chr8:110433885-110433965 4 1.66e-04 gcc tgtagtcc cagctccttc chr6:147858710-147858790 56 1.66e-04 ggcgggcacc tgtagtcc cagctactcg chr7:13121711-13121791 65 1.66e-04 ggcgggcgcc tgtagtcc tagctact chr6:105409431-105409511 47 2.86e-04 ggtttcacta tgttggcc aggctagtca chr7:110957056-110957136 51 2.86e-04 ggtttcacca tgttggcc agaatggtct chr1:191980796-191980876 36 2.86e-04 gatttcacca tgttggcc gggatggtct chr6:49610677-49610757 73 3.18e-04 gccaacacgg tgaagccc chr2:169834344-169834424 25 3.47e-04 aaaatgctcc tgtgatcc aatgacttcc chr21:38801872-38801952 42 3.47e-04 ggtgtgcccc tgtgatcc aatcaccttt chr1:61685257-61685337 5 4.22e-04 cgcc tgtaatct cagctatttg chr3:87862801-87862881 7 4.22e-04 tcaaat tgtaatct ccacgtgtcg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTAABCC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr15:48989283-48989363 1.5e-05 33_[+5]_39 chr2:38585542-38585622 1.5e-05 43_[+5]_29 chr2:62959547-62959627 1.5e-05 13_[+5]_59 chr12:28321981-28322061 1.5e-05 45_[+5]_27 chr1:61763734-61763814 1.5e-05 8_[+5]_64 chr4:186090372-186090452 1.5e-05 30_[+5]_42 chr2:48583427-48583507 1.5e-05 28_[+5]_44 chr4:74073637-74073717 1.5e-05 9_[+5]_63 chr6:68719104-68719184 1.5e-05 12_[+5]_60 chr3:152029666-152029746 1.5e-05 [+5]_72 chr5:90578222-90578302 1.5e-05 40_[+5]_32 chr2:58448077-58448157 1.5e-05 11_[+5]_61 chr21:31046795-31046875 1.5e-05 41_[+5]_31 chr4:74069213-74069293 1.5e-05 2_[+5]_70 chr6:135388045-135388125 1.5e-05 17_[+5]_55 chr4:80920325-80920405 1.5e-05 26_[+5]_46 chr10:11589713-11589793 6e-05 28_[+5]_44 chr1:145095684-145095764 0.0001 52_[+5]_20 chr9:71369267-71369347 0.0001 20_[+5]_52 chr11:16281701-16281781 0.0001 47_[+5]_25 chr1:191815053-191815133 0.0001 50_[+5]_22 chr2:185071516-185071596 0.0001 10_[+5]_62 chr12:33738425-33738505 0.0001 37_[+5]_35 chr11:124102569-12410264 0.0001 39_[+5]_33 chr11:5177713-5177793 0.0001 48_[+5]_24 chr3:135856559-135856639 0.0001 26_[+5]_46 chr11:95475761-95475841 0.0001 47_[+5]_25 chr1:212214990-212215070 0.0001 64_[+5]_8 chr16:53249028-53249108 0.0001 2_[+5]_70 chr2:158061851-158061931 0.0001 19_[+5]_53 chr10:22700945-22701025 0.0001 35_[+5]_37 chr5:43482084-43482164 0.0001 63_[+5]_9 chr9:37236575-37236655 0.0001 18_[+5]_54 chr1:28388277-28388357 0.0001 35_[+5]_37 chr5:65447852-65447932 0.0001 23_[+5]_49 chr12:70656225-70656305 0.0001 32_[+5]_40 chr21:15919225-15919305 0.0001 7_[+5]_65 chr4:80109523-80109603 0.00014 34_[+5]_38 chr4:68415777-68415857 0.00014 39_[+5]_33 chr8:28792202-28792282 0.00014 58_[+5]_14 chr21:22782237-22782317 0.00014 34_[+5]_38 chr21:15902413-15902493 0.00014 42_[+5]_30 chr3:172722889-172722969 0.00014 41_[+5]_31 chr2:48581498-48581578 0.00014 60_[+5]_12 chr3:84286734-84286814 0.00014 57_[+5]_15 chr6:129998337-129998417 0.00014 19_[+5]_53 chr7:106640008-106640088 0.00014 55_[+5]_17 chr2:158052676-158052756 0.00014 38_[+5]_34 chr1:144685427-144685507 0.00014 68_[+5]_4 chr7:135639450-135639530 0.00014 58_[+5]_14 chr12:28314128-28314208 0.00014 54_[+5]_18 chr6:49609667-49609747 0.00014 33_[+5]_39 chr12:23848651-23848731 0.00014 42_[+5]_30 chr7:123340017-123340097 0.00014 31_[+5]_41 chr17:57860336-57860416 0.00014 38_[+5]_34 chr2:48548438-48548518 0.00014 53_[+5]_19 chr6:13670803-13670883 0.00014 43_[+5]_29 chr11:97863862-97863942 0.00014 61_[+5]_11 chr10:22702212-22702292 0.00014 68_[+5]_4 chr11:16411277-16411357 0.00014 55_[+5]_17 chr1:85660712-85660792 0.00017 6_[+5]_66 chr3:151913961-151914041 0.00017 51_[+5]_21 chr6:158247348-158247428 0.00017 59_[+5]_13 chr21:16096553-16096633 0.00017 44_[+5]_28 chr6:49708680-49708760 0.00017 9_[+5]_63 chr8:110433885-110433965 0.00017 3_[+5]_69 chr6:147858710-147858790 0.00017 55_[+5]_17 chr7:13121711-13121791 0.00017 64_[+5]_8 chr6:105409431-105409511 0.00029 46_[+5]_26 chr7:110957056-110957136 0.00029 50_[+5]_22 chr1:191980796-191980876 0.00029 35_[+5]_37 chr6:49610677-49610757 0.00032 72_[+5] chr2:169834344-169834424 0.00035 24_[+5]_48 chr21:38801872-38801952 0.00035 41_[+5]_31 chr1:61685257-61685337 0.00042 4_[+5]_68 chr3:87862801-87862881 0.00042 6_[+5]_66 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTAABCC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGTAABCC width=8 seqs=76 chr15:48989283-48989363 ( 34) TGTAATCC 1 chr2:38585542-38585622 ( 44) TGTAATCC 1 chr2:62959547-62959627 ( 14) TGTAATCC 1 chr12:28321981-28322061 ( 46) TGTAATCC 1 chr1:61763734-61763814 ( 9) TGTAATCC 1 chr4:186090372-186090452 ( 31) TGTAATCC 1 chr2:48583427-48583507 ( 29) TGTAATCC 1 chr4:74073637-74073717 ( 10) TGTAATCC 1 chr6:68719104-68719184 ( 13) TGTAATCC 1 chr3:152029666-152029746 ( 1) TGTAATCC 1 chr5:90578222-90578302 ( 41) TGTAATCC 1 chr2:58448077-58448157 ( 12) TGTAATCC 1 chr21:31046795-31046875 ( 42) TGTAATCC 1 chr4:74069213-74069293 ( 3) TGTAATCC 1 chr6:135388045-135388125 ( 18) TGTAATCC 1 chr4:80920325-80920405 ( 27) TGTAATCC 1 chr10:11589713-11589793 ( 29) TGTTATCC 1 chr1:145095684-145095764 ( 53) TGTTAGCC 1 chr9:71369267-71369347 ( 21) TGTTAGCC 1 chr11:16281701-16281781 ( 48) TGTTAGCC 1 chr1:191815053-191815133 ( 51) TGTTAGCC 1 chr2:185071516-185071596 ( 11) TGTTAGCC 1 chr12:33738425-33738505 ( 38) TGTTAGCC 1 chr11:124102569-12410264 ( 40) TGTTAGCC 1 chr11:5177713-5177793 ( 49) TGTTAGCC 1 chr3:135856559-135856639 ( 27) TGTTAGCC 1 chr11:95475761-95475841 ( 48) TGTTAGCC 1 chr1:212214990-212215070 ( 65) TGTTAGCC 1 chr16:53249028-53249108 ( 3) TGTTAGCC 1 chr2:158061851-158061931 ( 20) TGTTAGCC 1 chr10:22700945-22701025 ( 36) TGTTAGCC 1 chr5:43482084-43482164 ( 64) TGTTAGCC 1 chr9:37236575-37236655 ( 19) TGTTAGCC 1 chr1:28388277-28388357 ( 36) TGTTAGCC 1 chr5:65447852-65447932 ( 24) TGTTAGCC 1 chr12:70656225-70656305 ( 33) TGTTAGCC 1 chr21:15919225-15919305 ( 8) TGTTAGCC 1 chr4:80109523-80109603 ( 35) TGAAACCC 1 chr4:68415777-68415857 ( 40) TGAAACCC 1 chr8:28792202-28792282 ( 59) TGAAACCC 1 chr21:22782237-22782317 ( 35) TGAAACCC 1 chr21:15902413-15902493 ( 43) TGAAACCC 1 chr3:172722889-172722969 ( 42) TGAAACCC 1 chr2:48581498-48581578 ( 61) TGAAACCC 1 chr3:84286734-84286814 ( 58) TGAAACCC 1 chr6:129998337-129998417 ( 20) TGAAACCC 1 chr7:106640008-106640088 ( 56) TGAAACCC 1 chr2:158052676-158052756 ( 39) TGAAACCC 1 chr1:144685427-144685507 ( 69) TGAAACCC 1 chr7:135639450-135639530 ( 59) TGAAACCC 1 chr12:28314128-28314208 ( 55) TGAAACCC 1 chr6:49609667-49609747 ( 34) TGAAACCC 1 chr12:23848651-23848731 ( 43) TGAAACCC 1 chr7:123340017-123340097 ( 32) TGAAACCC 1 chr17:57860336-57860416 ( 39) TGAAACCC 1 chr2:48548438-48548518 ( 54) TGAAACCC 1 chr6:13670803-13670883 ( 44) TGAAACCC 1 chr11:97863862-97863942 ( 62) TGAAACCC 1 chr10:22702212-22702292 ( 69) TGAAACCC 1 chr11:16411277-16411357 ( 56) TGAAACCC 1 chr1:85660712-85660792 ( 7) TGTAGTCC 1 chr3:151913961-151914041 ( 52) TGTAGTCC 1 chr6:158247348-158247428 ( 60) TGTAGTCC 1 chr21:16096553-16096633 ( 45) TGTAGTCC 1 chr6:49708680-49708760 ( 10) TGTAGTCC 1 chr8:110433885-110433965 ( 4) TGTAGTCC 1 chr6:147858710-147858790 ( 56) TGTAGTCC 1 chr7:13121711-13121791 ( 65) TGTAGTCC 1 chr6:105409431-105409511 ( 47) TGTTGGCC 1 chr7:110957056-110957136 ( 51) TGTTGGCC 1 chr1:191980796-191980876 ( 36) TGTTGGCC 1 chr6:49610677-49610757 ( 73) TGAAGCCC 1 chr2:169834344-169834424 ( 25) TGTGATCC 1 chr21:38801872-38801952 ( 42) TGTGATCC 1 chr1:61685257-61685337 ( 5) TGTAATCT 1 chr3:87862801-87862881 ( 7) TGTAATCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTAABCC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.09724 E= 1.9e-040 -1289 -1289 -1289 206 -1289 -1289 200 -1289 33 -1289 -1289 151 138 -1289 -324 40 174 -1289 -66 -1289 -1289 29 28 67 -1289 195 -1289 -1289 -1289 191 -1289 -319 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTAABCC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 76 E= 1.9e-040 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.315789 0.000000 0.000000 0.684211 0.657895 0.000000 0.026316 0.315789 0.842105 0.000000 0.157895 0.000000 0.000000 0.315789 0.302632 0.381579 0.000000 1.000000 0.000000 0.000000 0.000000 0.973684 0.000000 0.026316 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTAABCC MEME-5 regular expression -------------------------------------------------------------------------------- TG[TA][AT]A[TCG]CC -------------------------------------------------------------------------------- Time 18.97 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:79721047-79721127 6.78e-01 80 chr4:80920325-80920405 2.30e-03 26_[+5(1.47e-05)]_46 chr6:139825411-139825491 2.42e-02 53_[+4(3.16e-05)]_19 chr21:22576328-22576408 2.51e-01 80 chr1:197721950-197722030 6.49e-01 80 chr15:96308542-96308622 2.22e-02 11_[+2(4.44e-05)]_61 chr6:49610677-49610757 8.95e-06 29_[+2(1.54e-05)]_22_[+4(6.34e-05)]_\ 13 chr7:111073626-111073706 1.91e-01 80 chr19:966877-966957 2.29e-01 80 chr7:111077400-111077480 2.32e-01 80 chr7:106145251-106145331 3.50e-02 30_[+2(4.44e-05)]_42 chr6:118918101-118918181 4.61e-03 80 chr6:135388045-135388125 9.85e-03 17_[+5(1.47e-05)]_55 chr6:143515479-143515559 3.65e-01 80 chr11:16411277-16411357 4.07e-08 31_[+1(1.64e-05)]_3_[+4(3.16e-05)]_\ 17_[+3(4.52e-05)]_5 chr4:74069213-74069293 3.74e-08 2_[+5(1.47e-05)]_37_[+2(1.54e-05)]_\ [+1(1.64e-05)]_3_[+4(1.52e-05)]_6 chr6:49590807-49590887 4.28e-01 80 chr2:130986558-130986638 6.19e-01 80 chr10:22702212-22702292 2.51e-07 36_[+2(1.54e-05)]_[+1(1.64e-05)]_3_\ [+4(1.52e-05)]_17 chr2:152489862-152489942 8.52e-01 80 chr1:191980796-191980876 1.19e-04 56_[+3(1.53e-05)]_1_[+1(6.18e-05)]_\ 7 chr21:15919225-15919305 2.81e-05 28_[+3(4.52e-05)]_2_[+1(6.18e-05)]_\ 34 chr11:97863862-97863942 5.07e-06 37_[+1(1.64e-05)]_3_[+4(1.52e-05)]_\ 24 chr21:31046795-31046875 2.81e-03 41_[+5(1.47e-05)]_31 chr7:12813408-12813488 6.49e-02 80 chr21:30694447-30694527 2.74e-01 80 chr3:87862801-87862881 9.87e-02 80 chr4:127484672-127484752 2.03e-01 80 chr2:15683838-15683918 5.84e-02 80 chr7:110957056-110957136 2.47e-04 71_[+3(4.52e-05)]_1 chr6:13670803-13670883 7.07e-09 11_[+2(1.54e-05)]_[+1(1.64e-05)]_3_\ [+4(1.52e-05)]_42 chr21:38801872-38801952 5.56e-03 80 chr19:47334279-47334359 5.90e-01 80 chr1:197704746-197704826 2.49e-01 80 chr12:70656225-70656305 1.60e-05 53_[+3(4.52e-05)]_2_[+1(6.18e-05)]_\ 9 chr3:171752963-171753043 4.15e-01 80 chr12:1308176-1308256 1.40e-01 80 chr6:99392174-99392254 5.43e-01 80 chr22:37912584-37912664 7.77e-01 80 chr7:141452605-141452685 6.53e-01 80 chr4:48354958-48355038 1.27e-01 80 chr5:65447852-65447932 7.90e-06 44_[+3(4.52e-05)]_2_[+1(6.18e-05)]_\ 18 chr18:2230817-2230897 7.96e-01 80 chr2:48548438-48548518 2.06e-09 22_[+2(1.54e-05)]_[+1(1.64e-05)]_2_\ [+4(1.52e-05)]_17_[+3(4.52e-05)]_7 chr12:33813003-33813083 3.36e-05 18_[+4(1.52e-05)]_17_[+3(4.52e-05)]_\ 29 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80 chr4:68415777-68415857 5.49e-09 7_[+2(1.54e-05)]_[+1(1.64e-05)]_3_\ [+4(4.70e-05)]_17_[+3(4.52e-05)]_21 chr6:28833638-28833718 8.61e-01 80 chr5:10740678-10740758 8.16e-01 80 chr4:80109523-80109603 8.14e-09 2_[+2(7.47e-05)]_[+1(1.64e-05)]_3_\ [+4(1.52e-05)]_17_[+3(4.52e-05)]_26 chr18:34479399-34479479 1.99e-01 80 chr2:223801619-223801699 1.20e-02 80 chr6:64284414-64284494 4.76e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n07.farnam.hpc.yale.internal ********************************************************************************