******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/CBX5.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr6:105336101-105336181 1.0000 80 chr5:79538807-79538887 1.0000 80 chr1:93728368-93728448 1.0000 80 chr8:124679841-124679921 1.0000 80 chr4:116936376-116936456 1.0000 80 chr1:75191899-75191979 1.0000 80 chr1:246693933-246694013 1.0000 80 chr2:78256674-78256754 1.0000 80 chr11:57386949-57387029 1.0000 80 chr12:47947165-47947245 1.0000 80 chr4:187373303-187373383 1.0000 80 chr6:132244670-132244750 1.0000 80 chr19:23128522-23128602 1.0000 80 chr15:63536040-63536120 1.0000 80 chr8:131841316-131841396 1.0000 80 chr9:132276894-132276974 1.0000 80 chr7:106470114-106470194 1.0000 80 chr21:15791393-15791473 1.0000 80 chr5:159107257-159107337 1.0000 80 chr20:54775669-54775749 1.0000 80 chr8:102768655-102768735 1.0000 80 chr1:43053582-43053662 1.0000 80 chr4:56441838-56441918 1.0000 80 chr2:173390451-173390531 1.0000 80 chr3:71540474-71540554 1.0000 80 chr7:140724627-140724707 1.0000 80 chr7:99548586-99548666 1.0000 80 chr8:127616238-127616318 1.0000 80 chr2:183912664-183912744 1.0000 80 chr1:184996534-184996614 1.0000 80 chr1:212032898-212032978 1.0000 80 chr7:76838946-76839026 1.0000 80 chr7:97091080-97091160 1.0000 80 chr6:63362740-63362820 1.0000 80 chr11:74538113-74538193 1.0000 80 chr21:43213082-43213162 1.0000 80 chr19:22327353-22327433 1.0000 80 chr2:69128859-69128939 1.0000 80 chr8:8293293-8293373 1.0000 80 chr5:155221980-155222060 1.0000 80 chr18:8929498-8929578 1.0000 80 chr5:2553842-2553922 1.0000 80 chr2:158232046-158232126 1.0000 80 chr9:128771491-128771571 1.0000 80 chr21:34581010-34581090 1.0000 80 chr19:5515904-5515984 1.0000 80 chr11:70788861-70788941 1.0000 80 chr2:8699249-8699329 1.0000 80 chr6:167219850-167219930 1.0000 80 chr12:124426492-12442657 1.0000 80 chr2:151003567-151003647 1.0000 80 chr8:142994843-142994923 1.0000 80 chr4:75209883-75209963 1.0000 80 chr3:147599913-147599993 1.0000 80 chr2:125831173-125831253 1.0000 80 chr7:123057799-123057879 1.0000 80 chr7:18301872-18301952 1.0000 80 chr8:140558634-140558714 1.0000 80 chr6:150636083-150636163 1.0000 80 chr2:41722327-41722407 1.0000 80 chr4:38257324-38257404 1.0000 80 chr4:75522547-75522627 1.0000 80 chr2:13004229-13004309 1.0000 80 chr1:117409254-117409334 1.0000 80 chr17:26022452-26022532 1.0000 80 chr8:103689472-103689552 1.0000 80 chr4:151879286-151879366 1.0000 80 chr17:58510542-58510622 1.0000 80 chr7:135949192-135949272 1.0000 80 chr12:28522581-28522661 1.0000 80 chr20:62776971-62777051 1.0000 80 chr10:91896630-91896710 1.0000 80 chr6:20943418-20943498 1.0000 80 chr8:37850646-37850726 1.0000 80 chr11:106037971-10603805 1.0000 80 chr5:169732429-169732509 1.0000 80 chr6:140341520-140341600 1.0000 80 chr4:83686458-83686538 1.0000 80 chr19:9862320-9862400 1.0000 80 chr3:31648116-31648196 1.0000 80 chr6:68666387-68666467 1.0000 80 chr19:8917512-8917592 1.0000 80 chr2:240824474-240824554 1.0000 80 chr1:30036094-30036174 1.0000 80 chr5:2879995-2880075 1.0000 80 chr3:44898328-44898408 1.0000 80 chr11:43489669-43489749 1.0000 80 chr17:5713080-5713160 1.0000 80 chr2:214340314-214340394 1.0000 80 chr9:130655267-130655347 1.0000 80 chr16:83767884-83767964 1.0000 80 chr1:45355847-45355927 1.0000 80 chr6:2710846-2710926 1.0000 80 chr20:39160893-39160973 1.0000 80 chr6:90996772-90996852 1.0000 80 chr7:150004395-150004475 1.0000 80 chr19:22130731-22130811 1.0000 80 chr12:132888114-13288819 1.0000 80 chr7:96342512-96342592 1.0000 80 chr2:185392995-185393075 1.0000 80 chr1:61049514-61049594 1.0000 80 chr5:163754347-163754427 1.0000 80 chr3:46882130-46882210 1.0000 80 chr1:85079715-85079795 1.0000 80 chr11:44047429-44047509 1.0000 80 chr13:109258934-10925901 1.0000 80 chr17:37980070-37980150 1.0000 80 chr1:55109550-55109630 1.0000 80 chr18:13316225-13316305 1.0000 80 chr4:3382209-3382289 1.0000 80 chr5:85761040-85761120 1.0000 80 chr1:67533511-67533591 1.0000 80 chr2:86188330-86188410 1.0000 80 chr7:103675287-103675367 1.0000 80 chr11:77526077-77526157 1.0000 80 chr19:51905536-51905616 1.0000 80 chr11:94346448-94346528 1.0000 80 chr7:66717091-66717171 1.0000 80 chr2:38966851-38966931 1.0000 80 chr1:41359731-41359811 1.0000 80 chr4:65096586-65096666 1.0000 80 chr7:22685200-22685280 1.0000 80 chr11:10066387-10066467 1.0000 80 chr2:173058189-173058269 1.0000 80 chr13:92079306-92079386 1.0000 80 chr8:94953258-94953338 1.0000 80 chr9:96655221-96655301 1.0000 80 chr6:137153194-137153274 1.0000 80 chr1:196504983-196505063 1.0000 80 chr5:175605934-175606014 1.0000 80 chr3:158970718-158970798 1.0000 80 chr14:101676097-10167617 1.0000 80 chr17:26149302-26149382 1.0000 80 chr6:159390345-159390425 1.0000 80 chr1:181254254-181254334 1.0000 80 chr19:40531961-40532041 1.0000 80 chr9:11269184-11269264 1.0000 80 chr7:133640142-133640222 1.0000 80 chr21:34739894-34739974 1.0000 80 chr7:97726478-97726558 1.0000 80 chr10:125989457-12598953 1.0000 80 chr1:114906005-114906085 1.0000 80 chr1:62676795-62676875 1.0000 80 chr7:71252627-71252707 1.0000 80 chr12:92787421-92787501 1.0000 80 chr12:57258260-57258340 1.0000 80 chr7:1724785-1724865 1.0000 80 chr6:4979819-4979899 1.0000 80 chr10:37611561-37611641 1.0000 80 chr5:6656955-6657035 1.0000 80 chr1:235833637-235833717 1.0000 80 chr1:89084159-89084239 1.0000 80 chr20:48162266-48162346 1.0000 80 chr17:66328264-66328344 1.0000 80 chr4:4727939-4728019 1.0000 80 chr12:70857902-70857982 1.0000 80 chr8:75083772-75083852 1.0000 80 chr18:29358506-29358586 1.0000 80 chr6:125432527-125432607 1.0000 80 chr1:189238298-189238378 1.0000 80 chr2:6971540-6971620 1.0000 80 chr14:34889914-34889994 1.0000 80 chr6:161404591-161404671 1.0000 80 chr9:138921085-138921165 1.0000 80 chr4:26681066-26681146 1.0000 80 chr11:114458262-11445834 1.0000 80 chr6:169815439-169815519 1.0000 80 chr4:68526297-68526377 1.0000 80 chr2:11800186-11800266 1.0000 80 chr20:54607456-54607536 1.0000 80 chr8:9693411-9693491 1.0000 80 chr19:9597854-9597934 1.0000 80 chr16:67524784-67524864 1.0000 80 chr7:140728727-140728807 1.0000 80 chr5:154066241-154066321 1.0000 80 chr5:6889337-6889417 1.0000 80 chr7:46508523-46508603 1.0000 80 chr1:26697611-26697691 1.0000 80 chr8:62492875-62492955 1.0000 80 chr1:25962789-25962869 1.0000 80 chr4:80180051-80180131 1.0000 80 chr5:64525846-64525926 1.0000 80 chr1:159693117-159693197 1.0000 80 chr15:90922658-90922738 1.0000 80 chr3:45524477-45524557 1.0000 80 chr3:10211043-10211123 1.0000 80 chr16:53219817-53219897 1.0000 80 chr19:8134402-8134482 1.0000 80 chr12:57152663-57152743 1.0000 80 chr12:46900148-46900228 1.0000 80 chr11:69163334-69163414 1.0000 80 chr2:153718056-153718136 1.0000 80 chr18:67894809-67894889 1.0000 80 chr15:75434979-75435059 1.0000 80 chr19:21518675-21518755 1.0000 80 chr7:146207354-146207434 1.0000 80 chr7:156075663-156075743 1.0000 80 chr20:40228626-40228706 1.0000 80 chr2:31919128-31919208 1.0000 80 chr7:66822844-66822924 1.0000 80 chr2:149011416-149011496 1.0000 80 chr5:180255919-180255999 1.0000 80 chr6:142534691-142534771 1.0000 80 chr16:89934466-89934546 1.0000 80 chr3:12906914-12906994 1.0000 80 chr7:99536061-99536141 1.0000 80 chr3:178705688-178705768 1.0000 80 chr17:75170853-75170933 1.0000 80 chr21:21707062-21707142 1.0000 80 chr10:76576952-76577032 1.0000 80 chr10:61682820-61682900 1.0000 80 chr1:246992266-246992346 1.0000 80 chr11:74582223-74582303 1.0000 80 chr16:24724830-24724910 1.0000 80 chr7:33110066-33110146 1.0000 80 chr1:31100190-31100270 1.0000 80 chr10:35546505-35546585 1.0000 80 chr2:72613587-72613667 1.0000 80 chr17:7441548-7441628 1.0000 80 chr4:80710205-80710285 1.0000 80 chr10:21486917-21486997 1.0000 80 chr11:43805994-43806074 1.0000 80 chr1:239642684-239642764 1.0000 80 chr9:5708568-5708648 1.0000 80 chr5:117049446-117049526 1.0000 80 chr1:117286301-117286381 1.0000 80 chrX:62695244-62695324 1.0000 80 chr2:65114889-65114969 1.0000 80 chr4:178219305-178219385 1.0000 80 chr5:171406764-171406844 1.0000 80 chr15:80170584-80170664 1.0000 80 chr16:50705740-50705820 1.0000 80 chr9:35142214-35142294 1.0000 80 chr1:203064351-203064431 1.0000 80 chr12:51310238-51310318 1.0000 80 chr2:97096487-97096567 1.0000 80 chr1:171692499-171692579 1.0000 80 chr19:52158172-52158252 1.0000 80 chr1:20486670-20486750 1.0000 80 chr9:138787212-138787292 1.0000 80 chr4:88164736-88164816 1.0000 80 chr15:80660162-80660242 1.0000 80 chr9:35010505-35010585 1.0000 80 chr1:92551421-92551501 1.0000 80 chr7:120096888-120096968 1.0000 80 chr7:148733871-148733951 1.0000 80 chr2:171780483-171780563 1.0000 80 chr20:32324975-32325055 1.0000 80 chr2:128577794-128577874 1.0000 80 chr12:32059912-32059992 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_CBX5/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/CBX5.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.261 C 0.239 G 0.242 T 0.258 Background letter frequencies (from file dataset with add-one prior applied): A 0.261 C 0.239 G 0.242 T 0.258 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CWGCWGMM MEME-1 width = 8 sites = 180 llr = 1130 E-value = 1.1e-067 ******************************************************************************** -------------------------------------------------------------------------------- Motif CWGCWGMM MEME-1 Description -------------------------------------------------------------------------------- Simplified A :4::7:54 pos.-specific C 9::a:133 probability G 1:a::912 matrix T :61:3112 bits 2.1 1.9 * 1.7 * ** 1.4 * ** Relative 1.2 * ** * Entropy 1.0 ****** (9.1 bits) 0.8 ****** 0.6 ****** 0.4 ****** 0.2 ******** 0.0 -------- Multilevel CTGCAGAA consensus A T CC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGCWGMM MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr5:171406764-171406844 24 1.53e-05 tttctatttt ctgcagaa agggtacact chr3:12906914-12906994 44 1.53e-05 tgacaccctt ctgcagaa gtaaattgcc chr20:40228626-40228706 41 1.53e-05 cagcaccatt ctgcagaa gtaaatgtgc chr19:21518675-21518755 41 1.53e-05 attttacttt ctgcagaa agggtgctcc chr19:9597854-9597934 43 1.53e-05 accacccttt ctgcagaa agtaaaattg chr14:34889914-34889994 28 1.53e-05 caatttactt ctgcagaa gggtgctgcc chr1:235833637-235833717 25 1.53e-05 cagcaccctt ctgcagaa gtaaatgtgc chr21:34739894-34739974 41 1.53e-05 cagcactctt ctgcagaa gtaaatgtgc chr13:92079306-92079386 33 1.53e-05 cagaagtttg ctgcagaa atggagccct chr11:10066387-10066467 32 1.53e-05 gagcaccctt ctgcagaa gtaaattgcc chr7:66717091-66717171 31 1.53e-05 cagtttactt ctgcagaa gggtgctgcc chr12:124426492-12442657 37 1.53e-05 tgcacccttt ctgcagaa agtaaactag chr7:120096888-120096968 60 2.94e-05 ggctccactc ctgcagca aacttctgcc chr15:90922658-90922738 28 2.94e-05 ggctccaccc ctgcagca gtcttctgcc chr1:89084159-89084239 31 2.94e-05 ggctccaccc ctgcagca gacttctgcc chr9:96655221-96655301 22 2.94e-05 atctgcccag ctgcagca cccgattaaa chr1:41359731-41359811 58 2.94e-05 ggctttgccc ctgcagca gacttctgcc chr6:2710846-2710926 52 2.94e-05 atctccttgg ctgcagca cccaaataaa chr8:37850646-37850726 50 2.94e-05 ggctccaccc ctgcagca cacttctgcc chr4:151879286-151879366 43 2.94e-05 ggctccaccc ctgcagca cacctctgcc chr2:13004229-13004309 26 2.94e-05 ttctctttgg ctgcagca cccaaataaa chr11:74538113-74538193 28 2.94e-05 ggctccaccg ctgcagca gacttctgcc chr7:99548586-99548666 11 2.94e-05 ggctagttaa ctgcagca ggaacacgtc chr12:47947165-47947245 9 2.94e-05 cccctcag ctgcagca cccaattaaa chr1:75191899-75191979 42 2.94e-05 ggctccatcc ctgcagca tacctctgcc chr5:79538807-79538887 33 2.94e-05 atctccctgg ctgcagca cccgattaaa chr6:105336101-105336181 32 2.94e-05 atatccctgg ctgcagca cccgattaaa chr5:64525846-64525926 41 5.90e-05 gcagatttct cagcagaa tccctgctgg chr2:8699249-8699329 38 5.90e-05 agcagacttt cagcagaa actgtgggct chr2:69128859-69128939 44 5.90e-05 agtgtctcaa cagcagaa ctgatcaagc chr4:56441838-56441918 58 5.90e-05 gccagtttct cagcagaa attttggaag chr21:15791393-15791473 54 5.90e-05 gcagattttt cagcagaa accttatagc chr4:4727939-4728019 3 1.01e-04 CC CAGCAGCA GGAGCAAGTG chr1:85079715-85079795 67 1.01e-04 taatcgggtg ctgcagcc aagtta chr16:83767884-83767964 64 1.01e-04 tcgggtgctg ctgcagcc aaggaaatg chr20:62776971-62777051 71 1.01e-04 gttgcaatgg cagcagca ct chr1:212032898-212032978 35 1.01e-04 taatcgggtg ctgcagcc aagcagatgg chr19:52158172-52158252 19 1.44e-04 AGCCTGGTGA CAGCAGAC ATACAGCCGG chr2:97096487-97096567 51 1.44e-04 gtatgaccag ctgcagag aggagctacc chr15:80170584-80170664 49 1.44e-04 cactcagacc cagcagac tcaacatcca chr10:21486917-21486997 40 1.44e-04 aactctgtct ctgctgca aaccctgctg chr10:35546505-35546585 4 1.44e-04 ggc ctgcagag tctctgggag chr7:33110066-33110146 11 1.44e-04 aggcataagc ctgctgca ggggcggagc chr4:80180051-80180131 59 1.44e-04 ggatgaccag ctgcagag aggagctacc chr6:161404591-161404671 16 1.44e-04 aggcagaagt ctgctgca gggttggagc chr18:29358506-29358586 23 1.44e-04 gactgtttct ctgctgca ataccactgt chr1:62676795-62676875 29 1.44e-04 atcaggttga cagcagac ttatcactgg chr6:137153194-137153274 37 1.44e-04 tcctcccttg cagcagac ttctgcctgg chr1:67533511-67533591 21 1.44e-04 aggcagaagt ctgctgca caggggagcc chr13:109258934-10925901 32 1.44e-04 aggtagaagt ctgctgca ggggtggagc chr9:130655267-130655347 31 1.44e-04 aaccctttct ctgctgca acacccgcag chr6:140341520-140341600 35 1.44e-04 tccacccgtg cagcagac ttctgcttgg chr9:132276894-132276974 41 1.44e-04 ggaaggccag ctgcagag aggagctacc chr1:93728368-93728448 46 1.44e-04 tccacctcca cagcagac ttctgcttgg chr20:32324975-32325055 59 2.14e-04 cacacagagc cagctgaa caggagactg chr12:51310238-51310318 21 2.14e-04 atgactcttc ctgctgac tagcttctcc chr8:9693411-9693491 28 2.14e-04 gtgagaccaa ctgctgac ttctcaatgg chr7:22685200-22685280 27 2.14e-04 gctgagaaat ctgctgac agccttatga chr19:23128522-23128602 24 2.14e-04 ataacgtgtc ctgctgac aaactcctcc chr7:148733871-148733951 65 2.28e-04 taattgggtg ctgcagct gaggagat chr12:70857902-70857982 39 2.28e-04 tcatcgggtg ctgcagct gaggagatgg chr2:86188330-86188410 25 2.28e-04 tagctccttt ctgcagct ggtcatcctg chr4:3382209-3382289 47 2.28e-04 ggccccaccc ctgcagct aacttctact chr8:124679841-124679921 55 2.28e-04 taatcgggtg ctgcagct gaggaggtgg chr17:7441548-7441628 31 2.69e-04 agtggtgttg cagcagag aaagagttta chr1:31100190-31100270 47 2.69e-04 agcagggatg cagcagag aaagagtgta chr11:69163334-69163414 26 2.69e-04 gggtagctcc cagctgca gctggtcatc chr12:57152663-57152743 27 2.69e-04 gtagggtttg cagcagag aaagagttta chr7:133640142-133640222 3 2.69e-04 ct cagcagag aggagaccct chr7:97091080-97091160 41 2.69e-04 agaagtgttg cagcagag aaagagttta chr5:180255919-180255999 71 3.00e-04 tcctggtctc ctgcagta cc chr2:11800186-11800266 43 3.00e-04 GTACGGCAGC CAGCAGAT GACATACATG chr2:6971540-6971620 31 3.00e-04 cagaagggga cagcagat ttcccatcag chr7:123057799-123057879 42 3.00e-04 ggctccatcc ctgcagta aacttctgcc chr1:184996534-184996614 36 3.00e-04 ggctccaccc ctgcagta gacttatgcc chr2:78256674-78256754 51 3.00e-04 cactcagatc cagcagat taacatccaa chr21:21707062-21707142 27 3.55e-04 ctaagaatag cagctgac tcctaatctg chr2:149011416-149011496 67 3.55e-04 cactccaaac ctgctgag tcatgc chr16:53219817-53219897 44 3.55e-04 cagaagtgtg ctgcagga gtggagccct chr1:25962789-25962869 13 3.55e-04 cctgaaggta ctgcagga gaccaggccg chr14:101676097-10167617 21 3.55e-04 tgcaaggttt ctgctgag aaatctgctg chr1:196504983-196505063 61 3.55e-04 cactccaaac ctgctgag tcacactgtg chr2:38966851-38966931 19 3.55e-04 gtacaattaa cagctgac ttctcatctg chr11:94346448-94346528 27 3.55e-04 tgtaaggttt ctgctgag aaatctgctg chr18:13316225-13316305 48 3.55e-04 ctacggctga cagctgac ttttccacag chr7:150004395-150004475 2 3.55e-04 c ctgcagga gccaagaagt chr11:43489669-43489749 22 3.55e-04 ccaagactga cagctgac ttctcagcag chr5:2879995-2880075 23 3.55e-04 attagactta cagctgac ttttgagcag chr2:240824474-240824554 49 3.55e-04 ataagactaa cagctgac ttctcatcag chr5:155221980-155222060 23 3.55e-04 ataatactga cagctgac atgctagcag chr7:140724627-140724707 11 3.55e-04 tgcagggttt ctgctgag atgtctgctg chr6:125432527-125432607 42 3.84e-04 gctaagaaat ctgctgat agtctcatgg chr11:44047429-44047509 29 3.84e-04 gaaaagtcaa ctgctgat cttattaaga chr18:8929498-8929578 53 3.84e-04 ggaatgggtg ctgctgat tggttgggga chr11:106037971-10603805 12 4.53e-04 atcttttgtc ctgctgct cagctccctt chr11:43805994-43806074 25 4.95e-04 gggtgggggg cagcagga gaaatggtgg chr9:138921085-138921165 56 4.95e-04 ggtctcctct cagctgag agctgagcag chr12:92787421-92787501 33 4.95e-04 cacacccatc cagcagga agtagctaga chr8:94953258-94953338 55 4.95e-04 gggagctaac cagcagga attagtcatg chr1:61049514-61049594 48 4.95e-04 attcggaagt cagctgag tgacttacta chr9:35010505-35010585 36 5.25e-04 ataagattaa cagctgat ttgtcatcag chr4:178219305-178219385 47 5.25e-04 aactctttct ctgctgta acactgctgt chr1:26697611-26697691 70 5.25e-04 ACAGAGAAGG CAGCTGAT CTC chr6:169815439-169815519 36 5.25e-04 ataagaccga cagctgat gtttccgagg chr7:18301872-18301952 36 5.25e-04 ataaggctga cagctgat ttctcttcag chr7:140728727-140728807 43 5.94e-04 gatgtaaaat cagcagtc atttgaatag chr6:68666387-68666467 45 5.94e-04 cagaagtttc ctgcagtg gtggagccct chr4:75209883-75209963 53 5.94e-04 tccaccctgg cagcagtc ttctgcctgg chr20:54775669-54775749 66 5.94e-04 ctaaaagcaa ctgcagtg gtggact chr4:68526297-68526377 30 6.35e-04 tagaagttta ctgcaggg gtggggccct chr4:26681066-26681146 50 6.35e-04 cagaagtgtg ctgcaggg atggagccct chr5:159107257-159107337 32 6.35e-04 cagaagtttg ctgcaggg ttggagccct chr16:24724830-24724910 38 7.10e-04 aatgggaagt ctgctgtc atccttacct chr3:178705688-178705768 34 7.10e-04 tgttgcagca ctgctgtc tcagtgcatt chr7:103675287-103675367 70 7.10e-04 tggtctgtta ctgcacaa tgg chr4:83686458-83686538 46 7.10e-04 aacaagaagt ctgctgtc atcatccttg chr17:26022452-26022532 35 7.10e-04 ttatctacaa ctgcataa gacagacact chr19:8134402-8134482 35 7.37e-04 TTACTGACCC CTGCTGGC AGTCAGTGGG chr3:10211043-10211123 36 7.95e-04 cttatctcaa ctgcatca gacagacacc chr16:67524784-67524864 30 7.95e-04 gtcttctcac ctgcatca cccgattaaa chr1:117409254-117409334 40 7.95e-04 cttccatatc ctgcacca ccatgctgtt chr4:75522547-75522627 72 7.95e-04 gactagggca gtgcagaa g chr11:70788861-70788941 25 7.95e-04 CTCCTTAACT CTGCACCA AGCTGTACCG chr2:183912664-183912744 27 7.95e-04 tttccatatc ctgcacca ccatgccatt chr6:142534691-142534771 40 9.57e-04 ggctccacca gtgcagca cacttctgcc chr7:146207354-146207434 45 9.57e-04 cactccaaac ctgctgtg tcgtgctgta chr7:71252627-71252707 52 9.57e-04 AGGTCCGTGT CTGCTGTG TGGAGGAAGA chr19:40531961-40532041 33 9.57e-04 gataagaagt cagctgtc aatcgattgg chr5:175605934-175606014 73 9.57e-04 GTCATGGGGG CAGCAGGT chr7:96342512-96342592 66 9.98e-04 tggagaacat ctgctggg tagtgca chr2:128577794-128577874 73 1.16e-03 aggatcaagt ctgcatcc chr11:74582223-74582303 63 1.16e-03 agggacatgc ctgcatcc aagagtagca chr12:46900148-46900228 10 1.16e-03 gaaaacttt ctgcttaa aaacccaccg chr5:6656955-6657035 47 1.16e-03 caaggaagta cagcacca tgagggagag chr3:158970718-158970798 44 1.16e-03 TTTGGGTACA CAGCACCA TCTACTGGGT chr19:51905536-51905616 60 1.16e-03 tgatcagacc cagcacca ggccatgggg chr6:90996772-90996852 63 1.16e-03 agcatggttg ctgGAGAA GGGTATGGTG chr6:150636083-150636163 59 1.16e-03 TTAGGACATG CTGCTGGT CCCTCTGGTC chr21:34581010-34581090 47 1.16e-03 gatttcccca cagcatca gtggatccag chr5:2553842-2553922 27 1.16e-03 gttccattgt ctgctggt ctccattgtt chr7:106470114-106470194 43 1.16e-03 tctggagcaa ctggagaa ccacaaaaga chr9:138787212-138787292 67 1.35e-03 cagttttcaa gtgctgaa ggaaaa chr2:72613587-72613667 73 1.35e-03 tcactaccct gtgcagcc chr10:61682820-61682900 58 1.35e-03 gcatatttct catcagaa tcttcagagg chr11:77526077-77526157 19 1.35e-03 GGTGGTGTGA CTTCAGAC ATGAGGATCA chr12:132888114-13288819 8 1.35e-03 caatgac cagcacac agtcaaacgt chr1:45355847-45355927 40 1.35e-03 ttttgtcttc cagctgtg cctgcttatt chr17:58510542-58510622 46 1.35e-03 tccaccccta cagcatac ctctgcctgg chr11:57386949-57387029 59 1.35e-03 aaggcttgtc ctgcatag ccccatggac chr7:99536061-99536141 56 1.41e-03 gaggagatat cagctgtt aaacttattg chr3:45524477-45524557 23 1.41e-03 gcagttgctt ctgcacat cctccatggc chr7:97726478-97726558 56 1.41e-03 gatgaaaagt cagctgtt aatctcattg chr6:159390345-159390425 58 1.41e-03 gatgagaagt cagctgtt aatgttattg chr2:173058189-173058269 25 1.41e-03 gatgagaaat cagctgtt aatcttattg chr2:125831173-125831253 8 1.41e-03 caaaact ctgcatat gtcattccac chr1:117286301-117286381 34 1.65e-03 gggatgcagg cagcaccc ttctgcaaag chr10:125989457-12598953 29 1.65e-03 tcctcagccg cagcaccc gattaaagcc chr15:63536040-63536120 17 1.65e-03 aagggtatgg catcagca tctggtgagg chr17:75170853-75170933 61 1.70e-03 agggtgccgc ctgcatct gttacgactg chr1:171692499-171692579 65 1.93e-03 cacattccca gagcagcc attttaga chr1:239642684-239642764 47 1.93e-03 gctaacttta catcagac ccaatggaag chr17:26149302-26149382 52 1.93e-03 gacattccta gagcagcc attttagaga chr5:163754347-163754427 58 1.93e-03 gacactccca gagcagcc atccatagac chr7:76838946-76839026 45 1.93e-03 tccaccctgg catcagac ttctgcctgg chr6:132244670-132244750 3 2.02e-03 ca gtgcagct atctaagtca chr1:246693933-246694013 72 2.02e-03 agggtcatat ctgcatta c chr9:35142214-35142294 2 2.28e-03 t ctgctcag gtgagtgtga chr16:50705740-50705820 38 2.28e-03 tgaacagatt ctggtgca gtctagtgca chr2:65114889-65114969 6 2.28e-03 AGAGA CAGGAGAC AGTAAGAGAA chr1:159693117-159693197 9 2.28e-03 gagcgcta caggagac tgggccttat chr17:5713080-5713160 22 2.28e-03 atccactggg ctggtgca cacctaataa chr3:31648116-31648196 30 2.28e-03 cagaagtttg ctggagag gtggggccct chr8:8293293-8293373 8 2.28e-03 ccactgt cttctgac ttccattgtt chr3:71540474-71540554 15 2.28e-03 TTCTTAGCAT GTGCTGCC TGTTCACTAA chr8:75083772-75083852 21 2.61e-03 ttgctagact gtgcagga ccagtgttca chr3:44898328-44898408 10 2.61e-03 agcatggtg gtgcagga tatggaaggc chr12:28522581-28522661 47 2.61e-03 ctgtagcaaa cttctgcc tcgacatcca chr1:203064351-203064431 14 2.77e-03 gatgatttcc catcagat acaatgaagg chr5:6889337-6889417 12 2.77e-03 ctgacgtcac cagcatta aagtctttct chr7:156075663-156075743 47 3.33e-03 aacaagaagt catctgcc attcccatat -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGCWGMM MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:171406764-171406844 1.5e-05 23_[+1]_49 chr3:12906914-12906994 1.5e-05 43_[+1]_29 chr20:40228626-40228706 1.5e-05 40_[+1]_32 chr19:21518675-21518755 1.5e-05 40_[+1]_32 chr19:9597854-9597934 1.5e-05 42_[+1]_30 chr14:34889914-34889994 1.5e-05 27_[+1]_45 chr1:235833637-235833717 1.5e-05 24_[+1]_48 chr21:34739894-34739974 1.5e-05 40_[+1]_32 chr13:92079306-92079386 1.5e-05 32_[+1]_40 chr11:10066387-10066467 1.5e-05 31_[+1]_41 chr7:66717091-66717171 1.5e-05 30_[+1]_42 chr12:124426492-12442657 1.5e-05 36_[+1]_36 chr7:120096888-120096968 2.9e-05 59_[+1]_13 chr15:90922658-90922738 2.9e-05 27_[+1]_45 chr1:89084159-89084239 2.9e-05 30_[+1]_42 chr9:96655221-96655301 2.9e-05 21_[+1]_51 chr1:41359731-41359811 2.9e-05 57_[+1]_15 chr6:2710846-2710926 2.9e-05 51_[+1]_21 chr8:37850646-37850726 2.9e-05 49_[+1]_23 chr4:151879286-151879366 2.9e-05 42_[+1]_30 chr2:13004229-13004309 2.9e-05 25_[+1]_47 chr11:74538113-74538193 2.9e-05 27_[+1]_45 chr7:99548586-99548666 2.9e-05 10_[+1]_62 chr12:47947165-47947245 2.9e-05 8_[+1]_64 chr1:75191899-75191979 2.9e-05 41_[+1]_31 chr5:79538807-79538887 2.9e-05 32_[+1]_40 chr6:105336101-105336181 2.9e-05 31_[+1]_41 chr5:64525846-64525926 5.9e-05 40_[+1]_32 chr2:8699249-8699329 5.9e-05 37_[+1]_35 chr2:69128859-69128939 5.9e-05 43_[+1]_29 chr4:56441838-56441918 5.9e-05 57_[+1]_15 chr21:15791393-15791473 5.9e-05 53_[+1]_19 chr4:4727939-4728019 0.0001 2_[+1]_70 chr1:85079715-85079795 0.0001 66_[+1]_6 chr16:83767884-83767964 0.0001 63_[+1]_9 chr20:62776971-62777051 0.0001 70_[+1]_2 chr1:212032898-212032978 0.0001 34_[+1]_38 chr19:52158172-52158252 0.00014 18_[+1]_54 chr2:97096487-97096567 0.00014 50_[+1]_22 chr15:80170584-80170664 0.00014 48_[+1]_24 chr10:21486917-21486997 0.00014 39_[+1]_33 chr10:35546505-35546585 0.00014 3_[+1]_69 chr7:33110066-33110146 0.00014 10_[+1]_62 chr4:80180051-80180131 0.00014 58_[+1]_14 chr6:161404591-161404671 0.00014 15_[+1]_57 chr18:29358506-29358586 0.00014 22_[+1]_50 chr1:62676795-62676875 0.00014 28_[+1]_44 chr6:137153194-137153274 0.00014 36_[+1]_36 chr1:67533511-67533591 0.00014 20_[+1]_52 chr13:109258934-10925901 0.00014 31_[+1]_41 chr9:130655267-130655347 0.00014 30_[+1]_42 chr6:140341520-140341600 0.00014 34_[+1]_38 chr9:132276894-132276974 0.00014 40_[+1]_32 chr1:93728368-93728448 0.00014 45_[+1]_27 chr20:32324975-32325055 0.00021 58_[+1]_14 chr12:51310238-51310318 0.00021 20_[+1]_52 chr8:9693411-9693491 0.00021 27_[+1]_45 chr7:22685200-22685280 0.00021 26_[+1]_46 chr19:23128522-23128602 0.00021 23_[+1]_49 chr7:148733871-148733951 0.00023 64_[+1]_8 chr12:70857902-70857982 0.00023 38_[+1]_34 chr2:86188330-86188410 0.00023 24_[+1]_48 chr4:3382209-3382289 0.00023 46_[+1]_26 chr8:124679841-124679921 0.00023 54_[+1]_18 chr17:7441548-7441628 0.00027 30_[+1]_42 chr1:31100190-31100270 0.00027 46_[+1]_26 chr11:69163334-69163414 0.00027 25_[+1]_47 chr12:57152663-57152743 0.00027 26_[+1]_46 chr7:133640142-133640222 0.00027 2_[+1]_70 chr7:97091080-97091160 0.00027 40_[+1]_32 chr5:180255919-180255999 0.0003 70_[+1]_2 chr2:11800186-11800266 0.0003 42_[+1]_30 chr2:6971540-6971620 0.0003 30_[+1]_42 chr7:123057799-123057879 0.0003 41_[+1]_31 chr1:184996534-184996614 0.0003 35_[+1]_37 chr2:78256674-78256754 0.0003 50_[+1]_22 chr21:21707062-21707142 0.00036 26_[+1]_46 chr2:149011416-149011496 0.00036 66_[+1]_6 chr16:53219817-53219897 0.00036 43_[+1]_29 chr1:25962789-25962869 0.00036 12_[+1]_60 chr14:101676097-10167617 0.00036 20_[+1]_52 chr1:196504983-196505063 0.00036 60_[+1]_12 chr2:38966851-38966931 0.00036 18_[+1]_54 chr11:94346448-94346528 0.00036 26_[+1]_46 chr18:13316225-13316305 0.00036 47_[+1]_25 chr7:150004395-150004475 0.00036 1_[+1]_71 chr11:43489669-43489749 0.00036 21_[+1]_51 chr5:2879995-2880075 0.00036 22_[+1]_50 chr2:240824474-240824554 0.00036 48_[+1]_24 chr5:155221980-155222060 0.00036 22_[+1]_50 chr7:140724627-140724707 0.00036 10_[+1]_62 chr6:125432527-125432607 0.00038 41_[+1]_31 chr11:44047429-44047509 0.00038 28_[+1]_44 chr18:8929498-8929578 0.00038 52_[+1]_20 chr11:106037971-10603805 0.00045 11_[+1]_61 chr11:43805994-43806074 0.00049 24_[+1]_48 chr9:138921085-138921165 0.00049 55_[+1]_17 chr12:92787421-92787501 0.00049 32_[+1]_40 chr8:94953258-94953338 0.00049 54_[+1]_18 chr1:61049514-61049594 0.00049 47_[+1]_25 chr9:35010505-35010585 0.00052 35_[+1]_37 chr4:178219305-178219385 0.00052 46_[+1]_26 chr1:26697611-26697691 0.00052 69_[+1]_3 chr6:169815439-169815519 0.00052 35_[+1]_37 chr7:18301872-18301952 0.00052 35_[+1]_37 chr7:140728727-140728807 0.00059 42_[+1]_30 chr6:68666387-68666467 0.00059 44_[+1]_28 chr4:75209883-75209963 0.00059 52_[+1]_20 chr20:54775669-54775749 0.00059 65_[+1]_7 chr4:68526297-68526377 0.00064 29_[+1]_43 chr4:26681066-26681146 0.00064 49_[+1]_23 chr5:159107257-159107337 0.00064 31_[+1]_41 chr16:24724830-24724910 0.00071 37_[+1]_35 chr3:178705688-178705768 0.00071 33_[+1]_39 chr7:103675287-103675367 0.00071 69_[+1]_3 chr4:83686458-83686538 0.00071 45_[+1]_27 chr17:26022452-26022532 0.00071 34_[+1]_38 chr19:8134402-8134482 0.00074 34_[+1]_38 chr3:10211043-10211123 0.0008 35_[+1]_37 chr16:67524784-67524864 0.0008 29_[+1]_43 chr1:117409254-117409334 0.0008 39_[+1]_33 chr4:75522547-75522627 0.0008 71_[+1]_1 chr11:70788861-70788941 0.0008 24_[+1]_48 chr2:183912664-183912744 0.0008 26_[+1]_46 chr6:142534691-142534771 0.00096 39_[+1]_33 chr7:146207354-146207434 0.00096 44_[+1]_28 chr7:71252627-71252707 0.00096 51_[+1]_21 chr19:40531961-40532041 0.00096 32_[+1]_40 chr5:175605934-175606014 0.00096 72_[+1] chr7:96342512-96342592 0.001 65_[+1]_7 chr2:128577794-128577874 0.0012 72_[+1] chr11:74582223-74582303 0.0012 62_[+1]_10 chr12:46900148-46900228 0.0012 9_[+1]_63 chr5:6656955-6657035 0.0012 46_[+1]_26 chr3:158970718-158970798 0.0012 43_[+1]_29 chr19:51905536-51905616 0.0012 59_[+1]_13 chr6:90996772-90996852 0.0012 62_[+1]_10 chr6:150636083-150636163 0.0012 58_[+1]_14 chr21:34581010-34581090 0.0012 46_[+1]_26 chr5:2553842-2553922 0.0012 26_[+1]_46 chr7:106470114-106470194 0.0012 42_[+1]_30 chr9:138787212-138787292 0.0013 66_[+1]_6 chr2:72613587-72613667 0.0013 72_[+1] chr10:61682820-61682900 0.0013 57_[+1]_15 chr11:77526077-77526157 0.0013 18_[+1]_54 chr12:132888114-13288819 0.0013 7_[+1]_65 chr1:45355847-45355927 0.0013 39_[+1]_33 chr17:58510542-58510622 0.0013 45_[+1]_27 chr11:57386949-57387029 0.0013 58_[+1]_14 chr7:99536061-99536141 0.0014 55_[+1]_17 chr3:45524477-45524557 0.0014 22_[+1]_50 chr7:97726478-97726558 0.0014 55_[+1]_17 chr6:159390345-159390425 0.0014 57_[+1]_15 chr2:173058189-173058269 0.0014 24_[+1]_48 chr2:125831173-125831253 0.0014 7_[+1]_65 chr1:117286301-117286381 0.0017 33_[+1]_39 chr10:125989457-12598953 0.0017 28_[+1]_44 chr15:63536040-63536120 0.0017 16_[+1]_56 chr17:75170853-75170933 0.0017 60_[+1]_12 chr1:171692499-171692579 0.0019 64_[+1]_8 chr1:239642684-239642764 0.0019 46_[+1]_26 chr17:26149302-26149382 0.0019 51_[+1]_21 chr5:163754347-163754427 0.0019 57_[+1]_15 chr7:76838946-76839026 0.0019 44_[+1]_28 chr6:132244670-132244750 0.002 2_[+1]_70 chr1:246693933-246694013 0.002 71_[+1]_1 chr9:35142214-35142294 0.0023 1_[+1]_71 chr16:50705740-50705820 0.0023 37_[+1]_35 chr2:65114889-65114969 0.0023 5_[+1]_67 chr1:159693117-159693197 0.0023 8_[+1]_64 chr17:5713080-5713160 0.0023 21_[+1]_51 chr3:31648116-31648196 0.0023 29_[+1]_43 chr8:8293293-8293373 0.0023 7_[+1]_65 chr3:71540474-71540554 0.0023 14_[+1]_58 chr8:75083772-75083852 0.0026 20_[+1]_52 chr3:44898328-44898408 0.0026 9_[+1]_63 chr12:28522581-28522661 0.0026 46_[+1]_26 chr1:203064351-203064431 0.0028 13_[+1]_59 chr5:6889337-6889417 0.0028 11_[+1]_61 chr7:156075663-156075743 0.0033 46_[+1]_26 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGCWGMM MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CWGCWGMM width=8 seqs=180 chr5:171406764-171406844 ( 24) CTGCAGAA 1 chr3:12906914-12906994 ( 44) CTGCAGAA 1 chr20:40228626-40228706 ( 41) CTGCAGAA 1 chr19:21518675-21518755 ( 41) CTGCAGAA 1 chr19:9597854-9597934 ( 43) CTGCAGAA 1 chr14:34889914-34889994 ( 28) CTGCAGAA 1 chr1:235833637-235833717 ( 25) CTGCAGAA 1 chr21:34739894-34739974 ( 41) CTGCAGAA 1 chr13:92079306-92079386 ( 33) CTGCAGAA 1 chr11:10066387-10066467 ( 32) CTGCAGAA 1 chr7:66717091-66717171 ( 31) CTGCAGAA 1 chr12:124426492-12442657 ( 37) CTGCAGAA 1 chr7:120096888-120096968 ( 60) CTGCAGCA 1 chr15:90922658-90922738 ( 28) CTGCAGCA 1 chr1:89084159-89084239 ( 31) CTGCAGCA 1 chr9:96655221-96655301 ( 22) CTGCAGCA 1 chr1:41359731-41359811 ( 58) CTGCAGCA 1 chr6:2710846-2710926 ( 52) CTGCAGCA 1 chr8:37850646-37850726 ( 50) CTGCAGCA 1 chr4:151879286-151879366 ( 43) CTGCAGCA 1 chr2:13004229-13004309 ( 26) CTGCAGCA 1 chr11:74538113-74538193 ( 28) CTGCAGCA 1 chr7:99548586-99548666 ( 11) CTGCAGCA 1 chr12:47947165-47947245 ( 9) CTGCAGCA 1 chr1:75191899-75191979 ( 42) CTGCAGCA 1 chr5:79538807-79538887 ( 33) CTGCAGCA 1 chr6:105336101-105336181 ( 32) CTGCAGCA 1 chr5:64525846-64525926 ( 41) CAGCAGAA 1 chr2:8699249-8699329 ( 38) CAGCAGAA 1 chr2:69128859-69128939 ( 44) CAGCAGAA 1 chr4:56441838-56441918 ( 58) CAGCAGAA 1 chr21:15791393-15791473 ( 54) CAGCAGAA 1 chr4:4727939-4728019 ( 3) CAGCAGCA 1 chr1:85079715-85079795 ( 67) CTGCAGCC 1 chr16:83767884-83767964 ( 64) CTGCAGCC 1 chr20:62776971-62777051 ( 71) CAGCAGCA 1 chr1:212032898-212032978 ( 35) CTGCAGCC 1 chr19:52158172-52158252 ( 19) CAGCAGAC 1 chr2:97096487-97096567 ( 51) CTGCAGAG 1 chr15:80170584-80170664 ( 49) CAGCAGAC 1 chr10:21486917-21486997 ( 40) CTGCTGCA 1 chr10:35546505-35546585 ( 4) CTGCAGAG 1 chr7:33110066-33110146 ( 11) CTGCTGCA 1 chr4:80180051-80180131 ( 59) CTGCAGAG 1 chr6:161404591-161404671 ( 16) CTGCTGCA 1 chr18:29358506-29358586 ( 23) CTGCTGCA 1 chr1:62676795-62676875 ( 29) CAGCAGAC 1 chr6:137153194-137153274 ( 37) CAGCAGAC 1 chr1:67533511-67533591 ( 21) CTGCTGCA 1 chr13:109258934-10925901 ( 32) CTGCTGCA 1 chr9:130655267-130655347 ( 31) CTGCTGCA 1 chr6:140341520-140341600 ( 35) CAGCAGAC 1 chr9:132276894-132276974 ( 41) CTGCAGAG 1 chr1:93728368-93728448 ( 46) CAGCAGAC 1 chr20:32324975-32325055 ( 59) CAGCTGAA 1 chr12:51310238-51310318 ( 21) CTGCTGAC 1 chr8:9693411-9693491 ( 28) CTGCTGAC 1 chr7:22685200-22685280 ( 27) CTGCTGAC 1 chr19:23128522-23128602 ( 24) CTGCTGAC 1 chr7:148733871-148733951 ( 65) CTGCAGCT 1 chr12:70857902-70857982 ( 39) CTGCAGCT 1 chr2:86188330-86188410 ( 25) CTGCAGCT 1 chr4:3382209-3382289 ( 47) CTGCAGCT 1 chr8:124679841-124679921 ( 55) CTGCAGCT 1 chr17:7441548-7441628 ( 31) CAGCAGAG 1 chr1:31100190-31100270 ( 47) CAGCAGAG 1 chr11:69163334-69163414 ( 26) CAGCTGCA 1 chr12:57152663-57152743 ( 27) CAGCAGAG 1 chr7:133640142-133640222 ( 3) CAGCAGAG 1 chr7:97091080-97091160 ( 41) CAGCAGAG 1 chr5:180255919-180255999 ( 71) CTGCAGTA 1 chr2:11800186-11800266 ( 43) CAGCAGAT 1 chr2:6971540-6971620 ( 31) CAGCAGAT 1 chr7:123057799-123057879 ( 42) CTGCAGTA 1 chr1:184996534-184996614 ( 36) CTGCAGTA 1 chr2:78256674-78256754 ( 51) CAGCAGAT 1 chr21:21707062-21707142 ( 27) CAGCTGAC 1 chr2:149011416-149011496 ( 67) CTGCTGAG 1 chr16:53219817-53219897 ( 44) CTGCAGGA 1 chr1:25962789-25962869 ( 13) CTGCAGGA 1 chr14:101676097-10167617 ( 21) CTGCTGAG 1 chr1:196504983-196505063 ( 61) CTGCTGAG 1 chr2:38966851-38966931 ( 19) CAGCTGAC 1 chr11:94346448-94346528 ( 27) CTGCTGAG 1 chr18:13316225-13316305 ( 48) CAGCTGAC 1 chr7:150004395-150004475 ( 2) CTGCAGGA 1 chr11:43489669-43489749 ( 22) CAGCTGAC 1 chr5:2879995-2880075 ( 23) CAGCTGAC 1 chr2:240824474-240824554 ( 49) CAGCTGAC 1 chr5:155221980-155222060 ( 23) CAGCTGAC 1 chr7:140724627-140724707 ( 11) CTGCTGAG 1 chr6:125432527-125432607 ( 42) CTGCTGAT 1 chr11:44047429-44047509 ( 29) CTGCTGAT 1 chr18:8929498-8929578 ( 53) CTGCTGAT 1 chr11:106037971-10603805 ( 12) CTGCTGCT 1 chr11:43805994-43806074 ( 25) CAGCAGGA 1 chr9:138921085-138921165 ( 56) CAGCTGAG 1 chr12:92787421-92787501 ( 33) CAGCAGGA 1 chr8:94953258-94953338 ( 55) CAGCAGGA 1 chr1:61049514-61049594 ( 48) CAGCTGAG 1 chr9:35010505-35010585 ( 36) CAGCTGAT 1 chr4:178219305-178219385 ( 47) CTGCTGTA 1 chr1:26697611-26697691 ( 70) CAGCTGAT 1 chr6:169815439-169815519 ( 36) CAGCTGAT 1 chr7:18301872-18301952 ( 36) CAGCTGAT 1 chr7:140728727-140728807 ( 43) CAGCAGTC 1 chr6:68666387-68666467 ( 45) CTGCAGTG 1 chr4:75209883-75209963 ( 53) CAGCAGTC 1 chr20:54775669-54775749 ( 66) CTGCAGTG 1 chr4:68526297-68526377 ( 30) CTGCAGGG 1 chr4:26681066-26681146 ( 50) CTGCAGGG 1 chr5:159107257-159107337 ( 32) CTGCAGGG 1 chr16:24724830-24724910 ( 38) CTGCTGTC 1 chr3:178705688-178705768 ( 34) CTGCTGTC 1 chr7:103675287-103675367 ( 70) CTGCACAA 1 chr4:83686458-83686538 ( 46) CTGCTGTC 1 chr17:26022452-26022532 ( 35) CTGCATAA 1 chr19:8134402-8134482 ( 35) CTGCTGGC 1 chr3:10211043-10211123 ( 36) CTGCATCA 1 chr16:67524784-67524864 ( 30) CTGCATCA 1 chr1:117409254-117409334 ( 40) CTGCACCA 1 chr4:75522547-75522627 ( 72) GTGCAGAA 1 chr11:70788861-70788941 ( 25) CTGCACCA 1 chr2:183912664-183912744 ( 27) CTGCACCA 1 chr6:142534691-142534771 ( 40) GTGCAGCA 1 chr7:146207354-146207434 ( 45) CTGCTGTG 1 chr7:71252627-71252707 ( 52) CTGCTGTG 1 chr19:40531961-40532041 ( 33) CAGCTGTC 1 chr5:175605934-175606014 ( 73) CAGCAGGT 1 chr7:96342512-96342592 ( 66) CTGCTGGG 1 chr2:128577794-128577874 ( 73) CTGCATCC 1 chr11:74582223-74582303 ( 63) CTGCATCC 1 chr12:46900148-46900228 ( 10) CTGCTTAA 1 chr5:6656955-6657035 ( 47) CAGCACCA 1 chr3:158970718-158970798 ( 44) CAGCACCA 1 chr19:51905536-51905616 ( 60) CAGCACCA 1 chr6:90996772-90996852 ( 63) CTGGAGAA 1 chr6:150636083-150636163 ( 59) CTGCTGGT 1 chr21:34581010-34581090 ( 47) CAGCATCA 1 chr5:2553842-2553922 ( 27) CTGCTGGT 1 chr7:106470114-106470194 ( 43) CTGGAGAA 1 chr9:138787212-138787292 ( 67) GTGCTGAA 1 chr2:72613587-72613667 ( 73) GTGCAGCC 1 chr10:61682820-61682900 ( 58) CATCAGAA 1 chr11:77526077-77526157 ( 19) CTTCAGAC 1 chr12:132888114-13288819 ( 8) CAGCACAC 1 chr1:45355847-45355927 ( 40) CAGCTGTG 1 chr17:58510542-58510622 ( 46) CAGCATAC 1 chr11:57386949-57387029 ( 59) CTGCATAG 1 chr7:99536061-99536141 ( 56) CAGCTGTT 1 chr3:45524477-45524557 ( 23) CTGCACAT 1 chr7:97726478-97726558 ( 56) CAGCTGTT 1 chr6:159390345-159390425 ( 58) CAGCTGTT 1 chr2:173058189-173058269 ( 25) CAGCTGTT 1 chr2:125831173-125831253 ( 8) CTGCATAT 1 chr1:117286301-117286381 ( 34) CAGCACCC 1 chr10:125989457-12598953 ( 29) CAGCACCC 1 chr15:63536040-63536120 ( 17) CATCAGCA 1 chr17:75170853-75170933 ( 61) CTGCATCT 1 chr1:171692499-171692579 ( 65) GAGCAGCC 1 chr1:239642684-239642764 ( 47) CATCAGAC 1 chr17:26149302-26149382 ( 52) GAGCAGCC 1 chr5:163754347-163754427 ( 58) GAGCAGCC 1 chr7:76838946-76839026 ( 45) CATCAGAC 1 chr6:132244670-132244750 ( 3) GTGCAGCT 1 chr1:246693933-246694013 ( 72) CTGCATTA 1 chr9:35142214-35142294 ( 2) CTGCTCAG 1 chr16:50705740-50705820 ( 38) CTGGTGCA 1 chr2:65114889-65114969 ( 6) CAGGAGAC 1 chr1:159693117-159693197 ( 9) CAGGAGAC 1 chr17:5713080-5713160 ( 22) CTGGTGCA 1 chr3:31648116-31648196 ( 30) CTGGAGAG 1 chr8:8293293-8293373 ( 8) CTTCTGAC 1 chr3:71540474-71540554 ( 15) GTGCTGCC 1 chr8:75083772-75083852 ( 21) GTGCAGGA 1 chr3:44898328-44898408 ( 10) GTGCAGGA 1 chr12:28522581-28522661 ( 47) CTTCTGCC 1 chr1:203064351-203064431 ( 14) CATCAGAT 1 chr5:6889337-6889417 ( 12) CAGCATTA 1 chr7:156075663-156075743 ( 47) CATCTGCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGCWGMM MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 7.70244 E= 1.1e-067 -1414 197 -199 -1414 53 -1414 -1414 127 -1414 -1414 197 -237 -1414 201 -264 -1414 135 -1414 -1414 37 -1414 -184 183 -184 82 48 -145 -115 73 10 -64 -73 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGCWGMM MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 180 E= 1.1e-067 0.000000 0.938889 0.061111 0.000000 0.377778 0.000000 0.000000 0.622222 0.000000 0.000000 0.950000 0.050000 0.000000 0.961111 0.038889 0.000000 0.666667 0.000000 0.000000 0.333333 0.000000 0.066667 0.861111 0.072222 0.461111 0.333333 0.088889 0.116667 0.433333 0.255556 0.155556 0.155556 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CWGCWGMM MEME-1 regular expression -------------------------------------------------------------------------------- C[TA]GC[AT]G[AC][AC] -------------------------------------------------------------------------------- Time 4.96 secs. ******************************************************************************** ******************************************************************************** MOTIF TGCCTGGA MEME-2 width = 8 sites = 55 llr = 463 E-value = 4.0e-025 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGCCTGGA MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::7 pos.-specific C :1a8::23 probability G :9:::78: matrix T a::2a3:: bits 2.1 * 1.9 * * 1.7 *** * 1.4 *** * Relative 1.2 ***** * Entropy 1.0 ******** (12.1 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGCCTGGA consensus T TCC sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTGGA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr15:90922658-90922738 42 1.41e-05 agcagtcttc tgcctgga cacccagact chr4:26681066-26681146 24 1.41e-05 tatatgaaaa tgcctgga tatccaggca chr6:137153194-137153274 48 1.41e-05 agcagacttc tgcctgga cattcaggtg chr13:92079306-92079386 7 1.41e-05 tggaaa tgcctgga tgtccaggca chr1:41359731-41359811 72 1.41e-05 agcagacttc tgcctgga c chr13:109258934-10925901 9 1.41e-05 tatggaaa tgcctgga tatccaggta chr7:96342512-96342592 10 1.41e-05 gtatgaaaa tgcctgga tatccaggca chr3:31648116-31648196 4 1.41e-05 aaa tgcctgga tgtccaggca chr8:37850646-37850726 64 1.41e-05 agcacacttc tgcctgga catccaggt chr17:58510542-58510622 57 1.41e-05 agcatacctc tgcctgga cattcaagca chr4:151879286-151879366 57 1.41e-05 agcacacctc tgcctgga catccaggta chr4:75522547-75522627 5 1.41e-05 gaaa tgcctgga tgtccaggca chr7:123057799-123057879 56 1.41e-05 agtaaacttc tgcctgga catccaagcc chr4:75209883-75209963 64 1.41e-05 agcagtcttc tgcctgga tgcccaggc chr2:158232046-158232126 60 1.41e-05 agtaggattc tgcctgga cttccaggtt chr11:74538113-74538193 42 1.41e-05 agcagacttc tgcctgga catcccggca chr7:76838946-76839026 56 1.41e-05 atcagacttc tgcctgga catccgggca chr1:184996534-184996614 50 1.41e-05 agtagactta tgcctgga cattcaggca chr1:75191899-75191979 56 1.41e-05 agcatacctc tgcctgga cattcaggaa chr7:103675287-103675367 6 4.19e-05 ctcag tgcctggc aatcactaaa chr15:80660162-80660242 63 5.58e-05 ctgggggtca tgcctgca accatggatg chr7:146207354-146207434 29 5.58e-05 tgggattgtg tgcctgca ctccaaacct chr14:34889914-34889994 42 5.58e-05 agaagggtgc tgcctgca tctgaggcaa chr1:196504983-196505063 45 5.58e-05 cagagttgtg tgcctgca ctccaaacct chr7:66717091-66717171 45 5.58e-05 agaagggtgc tgcctgca tcaatcacga chr4:80710205-80710285 4 7.10e-05 aaa tgcttgga tgtccaggca chr8:62492875-62492955 48 7.10e-05 agcaaacttt tgcttgga catccaggca chr6:140341520-140341600 46 7.10e-05 agcagacttc tgcttgga catacaggca chr1:93728368-93728448 57 7.10e-05 agcagacttc tgcttgga cttccaggca chr4:178219305-178219385 21 8.47e-05 tctgctcaac tgccttgc agtaattaaa chr1:117286301-117286381 58 8.47e-05 aaagtaaatg tgccttgc tgagaaattt chr3:12906914-12906994 58 8.47e-05 agaagtaaat tgccttgc tgagagaatt chr20:40228626-40228706 56 8.47e-05 gaagtaaatg tgccttgc tgagaaattt chr18:67894809-67894889 12 8.47e-05 ctcgcttggc tgccttgc aataattaaa chr19:9597854-9597934 59 8.47e-05 aaagtaaaat tgccttgc tgagaaaatt chr1:235833637-235833717 40 8.47e-05 gaagtaaatg tgccttgc tgagaaatgt chr21:34739894-34739974 56 8.47e-05 gaagtaaatg tgccttgc tgagaaattt chr11:10066387-10066467 46 8.47e-05 agaagtaaat tgccttgc tgagaacgct chr7:66822844-66822924 38 1.12e-04 ccaccctaac tgcctgcc tgactggttt chr10:91896630-91896710 72 1.12e-04 tgtaggacca tgccttca a chr19:8917512-8917592 64 1.42e-04 ttactgatgc tgctttga aagcaatgt chr12:51310238-51310318 59 1.57e-04 gtgaaggtca tgcttgca tccatgggtg chr11:114458262-11445834 66 1.57e-04 ctatgggtta tgcttgca tcaatgg chr19:23128522-23128602 62 1.57e-04 gggaaggtca tgcttgca tccatgggta chr1:117409254-117409334 27 1.85e-04 actctaaata tgccttcc atatcctgca chr12:124426492-12442657 73 1.85e-04 agCCATCCAT TGCCTTCC chr6:142534691-142534771 54 2.00e-04 agcacacttc tgcctaga catctgggca chr2:151003567-151003647 6 2.00e-04 cccgt tgcctaga aagagccaat chr1:89084159-89084239 45 2.29e-04 agcagacttc tgccagga catcaaggca chr2:125831173-125831253 26 2.29e-04 gtcattccac tgctttgc atcttccatt chr5:159107257-159107337 63 2.29e-04 caagaacatc tgccagga cagcgaagga chr1:246992266-246992346 2 2.59e-04 t tgctttca gctcgtaagt chr17:5713080-5713160 71 2.86e-04 gtctctcttg tcccttga tt chr6:105336101-105336181 57 2.86e-04 aaagccttct tccctggc aatacttatt chr6:4979819-4979899 20 3.72e-04 gtgggattta tccttgga atgcaaggat -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTGGA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr15:90922658-90922738 1.4e-05 41_[+2]_31 chr4:26681066-26681146 1.4e-05 23_[+2]_49 chr6:137153194-137153274 1.4e-05 47_[+2]_25 chr13:92079306-92079386 1.4e-05 6_[+2]_66 chr1:41359731-41359811 1.4e-05 71_[+2]_1 chr13:109258934-10925901 1.4e-05 8_[+2]_64 chr7:96342512-96342592 1.4e-05 9_[+2]_63 chr3:31648116-31648196 1.4e-05 3_[+2]_69 chr8:37850646-37850726 1.4e-05 63_[+2]_9 chr17:58510542-58510622 1.4e-05 56_[+2]_16 chr4:151879286-151879366 1.4e-05 56_[+2]_16 chr4:75522547-75522627 1.4e-05 4_[+2]_68 chr7:123057799-123057879 1.4e-05 55_[+2]_17 chr4:75209883-75209963 1.4e-05 63_[+2]_9 chr2:158232046-158232126 1.4e-05 59_[+2]_13 chr11:74538113-74538193 1.4e-05 41_[+2]_31 chr7:76838946-76839026 1.4e-05 55_[+2]_17 chr1:184996534-184996614 1.4e-05 49_[+2]_23 chr1:75191899-75191979 1.4e-05 55_[+2]_17 chr7:103675287-103675367 4.2e-05 5_[+2]_67 chr15:80660162-80660242 5.6e-05 62_[+2]_10 chr7:146207354-146207434 5.6e-05 28_[+2]_44 chr14:34889914-34889994 5.6e-05 41_[+2]_31 chr1:196504983-196505063 5.6e-05 44_[+2]_28 chr7:66717091-66717171 5.6e-05 44_[+2]_28 chr4:80710205-80710285 7.1e-05 3_[+2]_69 chr8:62492875-62492955 7.1e-05 47_[+2]_25 chr6:140341520-140341600 7.1e-05 45_[+2]_27 chr1:93728368-93728448 7.1e-05 56_[+2]_16 chr4:178219305-178219385 8.5e-05 20_[+2]_52 chr1:117286301-117286381 8.5e-05 57_[+2]_15 chr3:12906914-12906994 8.5e-05 57_[+2]_15 chr20:40228626-40228706 8.5e-05 55_[+2]_17 chr18:67894809-67894889 8.5e-05 11_[+2]_61 chr19:9597854-9597934 8.5e-05 58_[+2]_14 chr1:235833637-235833717 8.5e-05 39_[+2]_33 chr21:34739894-34739974 8.5e-05 55_[+2]_17 chr11:10066387-10066467 8.5e-05 45_[+2]_27 chr7:66822844-66822924 0.00011 37_[+2]_35 chr10:91896630-91896710 0.00011 71_[+2]_1 chr19:8917512-8917592 0.00014 63_[+2]_9 chr12:51310238-51310318 0.00016 58_[+2]_14 chr11:114458262-11445834 0.00016 65_[+2]_7 chr19:23128522-23128602 0.00016 61_[+2]_11 chr1:117409254-117409334 0.00018 26_[+2]_46 chr12:124426492-12442657 0.00018 72_[+2] chr6:142534691-142534771 0.0002 53_[+2]_19 chr2:151003567-151003647 0.0002 5_[+2]_67 chr1:89084159-89084239 0.00023 44_[+2]_28 chr2:125831173-125831253 0.00023 25_[+2]_47 chr5:159107257-159107337 0.00023 62_[+2]_10 chr1:246992266-246992346 0.00026 1_[+2]_71 chr17:5713080-5713160 0.00029 70_[+2]_2 chr6:105336101-105336181 0.00029 56_[+2]_16 chr6:4979819-4979899 0.00037 19_[+2]_53 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTGGA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGCCTGGA width=8 seqs=55 chr15:90922658-90922738 ( 42) TGCCTGGA 1 chr4:26681066-26681146 ( 24) TGCCTGGA 1 chr6:137153194-137153274 ( 48) TGCCTGGA 1 chr13:92079306-92079386 ( 7) TGCCTGGA 1 chr1:41359731-41359811 ( 72) TGCCTGGA 1 chr13:109258934-10925901 ( 9) TGCCTGGA 1 chr7:96342512-96342592 ( 10) TGCCTGGA 1 chr3:31648116-31648196 ( 4) TGCCTGGA 1 chr8:37850646-37850726 ( 64) TGCCTGGA 1 chr17:58510542-58510622 ( 57) TGCCTGGA 1 chr4:151879286-151879366 ( 57) TGCCTGGA 1 chr4:75522547-75522627 ( 5) TGCCTGGA 1 chr7:123057799-123057879 ( 56) TGCCTGGA 1 chr4:75209883-75209963 ( 64) TGCCTGGA 1 chr2:158232046-158232126 ( 60) TGCCTGGA 1 chr11:74538113-74538193 ( 42) TGCCTGGA 1 chr7:76838946-76839026 ( 56) TGCCTGGA 1 chr1:184996534-184996614 ( 50) TGCCTGGA 1 chr1:75191899-75191979 ( 56) TGCCTGGA 1 chr7:103675287-103675367 ( 6) TGCCTGGC 1 chr15:80660162-80660242 ( 63) TGCCTGCA 1 chr7:146207354-146207434 ( 29) TGCCTGCA 1 chr14:34889914-34889994 ( 42) TGCCTGCA 1 chr1:196504983-196505063 ( 45) TGCCTGCA 1 chr7:66717091-66717171 ( 45) TGCCTGCA 1 chr4:80710205-80710285 ( 4) TGCTTGGA 1 chr8:62492875-62492955 ( 48) TGCTTGGA 1 chr6:140341520-140341600 ( 46) TGCTTGGA 1 chr1:93728368-93728448 ( 57) TGCTTGGA 1 chr4:178219305-178219385 ( 21) TGCCTTGC 1 chr1:117286301-117286381 ( 58) TGCCTTGC 1 chr3:12906914-12906994 ( 58) TGCCTTGC 1 chr20:40228626-40228706 ( 56) TGCCTTGC 1 chr18:67894809-67894889 ( 12) TGCCTTGC 1 chr19:9597854-9597934 ( 59) TGCCTTGC 1 chr1:235833637-235833717 ( 40) TGCCTTGC 1 chr21:34739894-34739974 ( 56) TGCCTTGC 1 chr11:10066387-10066467 ( 46) TGCCTTGC 1 chr7:66822844-66822924 ( 38) TGCCTGCC 1 chr10:91896630-91896710 ( 72) TGCCTTCA 1 chr19:8917512-8917592 ( 64) TGCTTTGA 1 chr12:51310238-51310318 ( 59) TGCTTGCA 1 chr11:114458262-11445834 ( 66) TGCTTGCA 1 chr19:23128522-23128602 ( 62) TGCTTGCA 1 chr1:117409254-117409334 ( 27) TGCCTTCC 1 chr12:124426492-12442657 ( 73) TGCCTTCC 1 chr6:142534691-142534771 ( 54) TGCCTAGA 1 chr2:151003567-151003647 ( 6) TGCCTAGA 1 chr1:89084159-89084239 ( 45) TGCCAGGA 1 chr2:125831173-125831253 ( 26) TGCTTTGC 1 chr5:159107257-159107337 ( 63) TGCCAGGA 1 chr1:246992266-246992346 ( 2) TGCTTTCA 1 chr17:5713080-5713160 ( 71) TCCCTTGA 1 chr6:105336101-105336181 ( 57) TCCCTGGC 1 chr6:4979819-4979899 ( 20) TCCTTGGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTGGA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.95894 E= 4.0e-025 -1243 -1243 -1243 195 -1243 -213 196 -1243 -1243 207 -1243 -1243 -1243 174 -1243 -37 -284 -1243 -1243 190 -284 -1243 147 17 -1243 -2 166 -1243 148 19 -1243 -1243 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTGGA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 55 E= 4.0e-025 0.000000 0.000000 0.000000 1.000000 0.000000 0.054545 0.945455 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.200000 0.036364 0.000000 0.000000 0.963636 0.036364 0.000000 0.672727 0.290909 0.000000 0.236364 0.763636 0.000000 0.727273 0.272727 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGCCTGGA MEME-2 regular expression -------------------------------------------------------------------------------- TGC[CT]T[GT][GC][AC] -------------------------------------------------------------------------------- Time 8.41 secs. ******************************************************************************** ******************************************************************************** MOTIF CTCCATGG MEME-3 width = 8 sites = 94 llr = 666 E-value = 2.1e-022 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTCCATGG MEME-3 Description -------------------------------------------------------------------------------- Simplified A 2:::9:13 pos.-specific C 638a:::: probability G ::::::77 matrix T 372:1a2: bits 2.1 * 1.9 * 1.7 * * 1.4 * * Relative 1.2 **** * Entropy 1.0 ***** * (10.2 bits) 0.8 ******* 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTCCATGG consensus TC TA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCCATGG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr9:5708568-5708648 19 1.39e-05 gttctctggc ctccatgg tttcctatga chr7:99536061-99536141 34 1.39e-05 gtcttctggc ctccatgg ttttgaggag chr3:45524477-45524557 32 1.39e-05 tctgcacatc ctccatgg ccacacctag chr7:97726478-97726558 33 1.39e-05 accttctggc ctccatgg tttctgatga chr11:57386949-57387029 67 2.68e-05 tcctgcatag ccccatgg acactt chr2:128577794-128577874 52 4.18e-05 gttcctccgg ttccatgg ctgaggatca chr15:80660162-80660242 45 4.18e-05 gttcctctgt ttccatgg ctgggggtca chr8:94953258-94953338 2 4.18e-05 a ttccatgg atgctagcat chr8:131841316-131841396 40 4.18e-05 gttcctctgg ttccatgg ccgaggtcac chr1:246693933-246694013 51 4.18e-05 gttcctccga ttccatgg ctgagggtca chr1:246992266-246992346 22 7.15e-05 tcgtaagtct ctccattg tgttctagct chr8:62492875-62492955 15 7.15e-05 agcagaggtt ctccatga gggctccacc chr7:140728727-140728807 20 7.15e-05 gttttctggt ctccatga tttcggatgt chr1:89084159-89084239 12 7.15e-05 aatagaggtt ctccatga gggctccacc chr19:40531961-40532041 10 7.15e-05 cttcatccc ctccattg ctttggataa chr6:137153194-137153274 15 7.15e-05 agcaaaggtt ctccatga gggctcctcc chr2:173058189-173058269 2 7.15e-05 c ctccatga tttctgatga chr1:41359731-41359811 39 7.15e-05 agcagaggtt ctccatga gggctttgcc chr6:140341520-140341600 13 7.15e-05 agtagaggtt ctccatga gggctccacc chr11:106037971-10603805 48 7.15e-05 caaatgcttt ctccattg caacaccatt chr17:58510542-58510622 24 7.15e-05 aggaaaggtt ctccatga gggctccacc chr7:123057799-123057879 23 7.15e-05 agcagtgggc ctccatga gggctccatc chr5:2553842-2553922 35 7.15e-05 gtctgctggt ctccattg tttctgataa chr7:76838946-76839026 23 7.15e-05 agtagaggtt ctccatga gggctccacc chr1:184996534-184996614 17 7.15e-05 agtagaagtt ctccatga gggctccacc chr1:75191899-75191979 23 7.15e-05 gaggtaggtt ctccatga gggctccatc chr1:93728368-93728448 24 7.15e-05 agtagaggtt ctccatga gggctccacc chr1:189238298-189238378 30 8.67e-05 cattaccttc atccatgg attctggggg chr4:65096586-65096666 6 8.67e-05 atgtc atccatgg atgcaagcat chr19:22130731-22130811 70 8.67e-05 tcatgctcgc atccatgg gta chr19:22327353-22327433 67 8.67e-05 tcatgcttcc atccatgg gtaaca chr9:35142214-35142294 45 1.02e-04 atgcctccca cttcatgg atgaaggtca chr6:2710846-2710926 44 1.29e-04 gatctcccat ctccttgg ctgcagcacc chr2:214340314-214340394 28 1.57e-04 tatgaccttc ccccatga agcagaaagg chr8:37850646-37850726 31 1.57e-04 agcaaaggtt ccccatga gggctccacc chr15:75434979-75435059 3 1.86e-04 cc acccatgg gtgcaagtgt chr5:64525846-64525926 15 1.86e-04 tacaagggaa ctccatag gtctatcagc chr7:46508523-46508603 27 1.86e-04 catgaccttc acccatgg atccagagga chr7:1724785-1724865 10 1.86e-04 ccttctttc ctccatag tttctgatga chr9:11269184-11269264 28 1.86e-04 catcaccttc acccatgg atctagaaga chr1:55109550-55109630 21 1.86e-04 tccttttggc ctccatag tttcagatga chr19:23128522-23128602 44 1.86e-04 actcctccgg acccatgg gggaaggtca chr6:142534691-142534771 21 2.18e-04 tgtagaggtg ttccatga gggctccacc chr1:181254254-181254334 3 2.18e-04 ca ttccattg tcatctggct chr1:61049514-61049594 25 2.18e-04 gtcctccgcc ttccattg ttgctattcg chr2:125831173-125831253 37 2.18e-04 gctttgcatc ttccattg ttacagatga chr8:8293293-8293373 16 2.18e-04 gtcttctgac ttccattg ttgctgtaaa chr7:33110066-33110146 29 2.32e-04 ggggcggagc cctcatgg agaacctcta chr16:53219817-53219897 59 2.32e-04 ggagtggagc cctcatgg agaacctctg chr4:68526297-68526377 45 2.32e-04 ggggtggggc cctcatgg agaacttctt chr4:26681066-26681146 65 2.32e-04 gggatggagc cctcatgg agaacctc chr6:161404591-161404671 34 2.32e-04 gggttggagc cctcatgg agaacctcta chr12:57258260-57258340 57 2.32e-04 gggatggagc cctcatgg agaacctcta chr17:37980070-37980150 54 2.32e-04 ggggtggagc cctcatgg agaacctctg chr7:96342512-96342592 51 2.32e-04 gaagtgtagc cctcatgg agaacatctg chr6:68666387-68666467 60 2.32e-04 gtggtggagc cctcatgg agaacctctg chr4:75522547-75522627 46 2.32e-04 agggtgcagc cctcatgg agaaccttga chr6:20943418-20943498 11 2.48e-04 gaggttatgt ctccatta cactctggct chr12:51310238-51310318 41 2.97e-04 gcttctccag atccattg gtgaaggtca chr2:72613587-72613667 40 2.97e-04 gacagaatgg tttcatgg gccagaacca chr11:114458262-11445834 30 2.97e-04 actaatccca atccattg gttcctctgg chr2:41722327-41722407 45 2.97e-04 gctcctctgg atccatga tggaggttca chr11:43805994-43806074 59 3.09e-04 tccttattcc ccccttgg agaatttcac chr17:66328264-66328344 59 3.09e-04 ttagagacct ccccttgg gaacgcattc chr6:159390345-159390425 35 3.42e-04 gccttttggc cttcatga tgtgggatga chr19:51905536-51905616 13 3.42e-04 tcaccgggat cttcattg tcccatgttg chr16:67524784-67524864 54 3.87e-04 taaagccttc ttccttgg caataattgt chr10:125989457-12598953 50 3.87e-04 taaagccttc ttccttgg caacaatcat chr9:96655221-96655301 46 3.87e-04 taaagccttc ttccttgg caatacttgc chr12:47947165-47947245 33 3.87e-04 taaagccttc ttccttgg caacactcgt chr5:79538807-79538887 57 3.87e-04 taaagccttc ttccttgg caatccttgt chr10:37611561-37611641 34 4.16e-04 gtatgactaa tcccattg cttagctccc chr11:44047429-44047509 3 4.62e-04 ct ttccatag tttctgatga chr19:8917512-8917592 20 4.62e-04 gtcttcttgc ttccatag tttcttttga chr10:91896630-91896710 52 4.62e-04 tttcatccag ttccatag cttgtaggac chr2:158232046-158232126 27 4.62e-04 ggtagaggtt ctccttga gggctccacc chr21:43213082-43213162 15 4.62e-04 tggcttgcat ctccttga tgtgaatttg chr12:32059912-32059992 67 5.53e-04 ctcctgtccc acccattg gtctct chr6:125432527-125432607 52 5.53e-04 ctgctgatag tctcatgg ggattccctt chr17:5713080-5713160 53 5.53e-04 ctcctgtctc acccattg gtctctcttg chr8:103689472-103689552 63 5.53e-04 gggctactgc tctcatgg agcatgtagt chr3:147599913-147599993 14 5.53e-04 tgcaacctcc acccatga attgggaagg chr6:63362740-63362820 24 5.53e-04 catgaccttc acccatga tcctggaggg chr7:71252627-71252707 29 6.02e-04 GTCCGCATCC ATCCATAG TCCATAGGTC chr5:163754347-163754427 66 6.02e-04 cagagcagcc atccatag acctccc chr2:97096487-97096567 71 6.44e-04 gagctaccca ctccaggg cc chr9:132276894-132276974 61 6.44e-04 gagctaccca ctccaggg cctcctctga chr2:65114889-65114969 44 7.84e-04 TCCTCAtttc cccctttg agaacctcat chr1:114906005-114906085 51 7.84e-04 tccttattcc cccctttg agaactttac chr8:140558634-140558714 34 7.84e-04 GCCTCCttcc cccctttg agaacctcac chr15:63536040-63536120 44 8.30e-04 gaccttcatg cttcatta tctcatgctg chr11:94346448-94346528 59 9.12e-04 cctatgaggg ttcctttg tatgtaataa chr1:67533511-67533591 38 1.06e-03 acaggggagc cctcatag agaacgtctg chr4:80180051-80180131 11 1.13e-03 gagctactca ttccaggg cctcctctct -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCCATGG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr9:5708568-5708648 1.4e-05 18_[+3]_54 chr7:99536061-99536141 1.4e-05 33_[+3]_39 chr3:45524477-45524557 1.4e-05 31_[+3]_41 chr7:97726478-97726558 1.4e-05 32_[+3]_40 chr11:57386949-57387029 2.7e-05 66_[+3]_6 chr2:128577794-128577874 4.2e-05 51_[+3]_21 chr15:80660162-80660242 4.2e-05 44_[+3]_28 chr8:94953258-94953338 4.2e-05 1_[+3]_71 chr8:131841316-131841396 4.2e-05 39_[+3]_33 chr1:246693933-246694013 4.2e-05 50_[+3]_22 chr1:246992266-246992346 7.2e-05 21_[+3]_51 chr8:62492875-62492955 7.2e-05 14_[+3]_58 chr7:140728727-140728807 7.2e-05 19_[+3]_53 chr1:89084159-89084239 7.2e-05 11_[+3]_61 chr19:40531961-40532041 7.2e-05 9_[+3]_63 chr6:137153194-137153274 7.2e-05 14_[+3]_58 chr2:173058189-173058269 7.2e-05 1_[+3]_71 chr1:41359731-41359811 7.2e-05 38_[+3]_34 chr6:140341520-140341600 7.2e-05 12_[+3]_60 chr11:106037971-10603805 7.2e-05 47_[+3]_25 chr17:58510542-58510622 7.2e-05 23_[+3]_49 chr7:123057799-123057879 7.2e-05 22_[+3]_50 chr5:2553842-2553922 7.2e-05 34_[+3]_38 chr7:76838946-76839026 7.2e-05 22_[+3]_50 chr1:184996534-184996614 7.2e-05 16_[+3]_56 chr1:75191899-75191979 7.2e-05 22_[+3]_50 chr1:93728368-93728448 7.2e-05 23_[+3]_49 chr1:189238298-189238378 8.7e-05 29_[+3]_43 chr4:65096586-65096666 8.7e-05 5_[+3]_67 chr19:22130731-22130811 8.7e-05 69_[+3]_3 chr19:22327353-22327433 8.7e-05 66_[+3]_6 chr9:35142214-35142294 0.0001 44_[+3]_28 chr6:2710846-2710926 0.00013 43_[+3]_29 chr2:214340314-214340394 0.00016 27_[+3]_45 chr8:37850646-37850726 0.00016 30_[+3]_42 chr15:75434979-75435059 0.00019 2_[+3]_70 chr5:64525846-64525926 0.00019 14_[+3]_58 chr7:46508523-46508603 0.00019 26_[+3]_46 chr7:1724785-1724865 0.00019 9_[+3]_63 chr9:11269184-11269264 0.00019 27_[+3]_45 chr1:55109550-55109630 0.00019 20_[+3]_52 chr19:23128522-23128602 0.00019 43_[+3]_29 chr6:142534691-142534771 0.00022 20_[+3]_52 chr1:181254254-181254334 0.00022 2_[+3]_70 chr1:61049514-61049594 0.00022 24_[+3]_48 chr2:125831173-125831253 0.00022 36_[+3]_36 chr8:8293293-8293373 0.00022 15_[+3]_57 chr7:33110066-33110146 0.00023 28_[+3]_44 chr16:53219817-53219897 0.00023 58_[+3]_14 chr4:68526297-68526377 0.00023 44_[+3]_28 chr4:26681066-26681146 0.00023 64_[+3]_8 chr6:161404591-161404671 0.00023 33_[+3]_39 chr12:57258260-57258340 0.00023 56_[+3]_16 chr17:37980070-37980150 0.00023 53_[+3]_19 chr7:96342512-96342592 0.00023 50_[+3]_22 chr6:68666387-68666467 0.00023 59_[+3]_13 chr4:75522547-75522627 0.00023 45_[+3]_27 chr6:20943418-20943498 0.00025 10_[+3]_62 chr12:51310238-51310318 0.0003 40_[+3]_32 chr2:72613587-72613667 0.0003 39_[+3]_33 chr11:114458262-11445834 0.0003 29_[+3]_43 chr2:41722327-41722407 0.0003 44_[+3]_28 chr11:43805994-43806074 0.00031 58_[+3]_14 chr17:66328264-66328344 0.00031 58_[+3]_14 chr6:159390345-159390425 0.00034 34_[+3]_38 chr19:51905536-51905616 0.00034 12_[+3]_60 chr16:67524784-67524864 0.00039 53_[+3]_19 chr10:125989457-12598953 0.00039 49_[+3]_23 chr9:96655221-96655301 0.00039 45_[+3]_27 chr12:47947165-47947245 0.00039 32_[+3]_40 chr5:79538807-79538887 0.00039 56_[+3]_16 chr10:37611561-37611641 0.00042 33_[+3]_39 chr11:44047429-44047509 0.00046 2_[+3]_70 chr19:8917512-8917592 0.00046 19_[+3]_53 chr10:91896630-91896710 0.00046 51_[+3]_21 chr2:158232046-158232126 0.00046 26_[+3]_46 chr21:43213082-43213162 0.00046 14_[+3]_58 chr12:32059912-32059992 0.00055 66_[+3]_6 chr6:125432527-125432607 0.00055 51_[+3]_21 chr17:5713080-5713160 0.00055 52_[+3]_20 chr8:103689472-103689552 0.00055 62_[+3]_10 chr3:147599913-147599993 0.00055 13_[+3]_59 chr6:63362740-63362820 0.00055 23_[+3]_49 chr7:71252627-71252707 0.0006 28_[+3]_44 chr5:163754347-163754427 0.0006 65_[+3]_7 chr2:97096487-97096567 0.00064 70_[+3]_2 chr9:132276894-132276974 0.00064 60_[+3]_12 chr2:65114889-65114969 0.00078 43_[+3]_29 chr1:114906005-114906085 0.00078 50_[+3]_22 chr8:140558634-140558714 0.00078 33_[+3]_39 chr15:63536040-63536120 0.00083 43_[+3]_29 chr11:94346448-94346528 0.00091 58_[+3]_14 chr1:67533511-67533591 0.0011 37_[+3]_35 chr4:80180051-80180131 0.0011 10_[+3]_62 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCCATGG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTCCATGG width=8 seqs=94 chr9:5708568-5708648 ( 19) CTCCATGG 1 chr7:99536061-99536141 ( 34) CTCCATGG 1 chr3:45524477-45524557 ( 32) CTCCATGG 1 chr7:97726478-97726558 ( 33) CTCCATGG 1 chr11:57386949-57387029 ( 67) CCCCATGG 1 chr2:128577794-128577874 ( 52) TTCCATGG 1 chr15:80660162-80660242 ( 45) TTCCATGG 1 chr8:94953258-94953338 ( 2) TTCCATGG 1 chr8:131841316-131841396 ( 40) TTCCATGG 1 chr1:246693933-246694013 ( 51) TTCCATGG 1 chr1:246992266-246992346 ( 22) CTCCATTG 1 chr8:62492875-62492955 ( 15) CTCCATGA 1 chr7:140728727-140728807 ( 20) CTCCATGA 1 chr1:89084159-89084239 ( 12) CTCCATGA 1 chr19:40531961-40532041 ( 10) CTCCATTG 1 chr6:137153194-137153274 ( 15) CTCCATGA 1 chr2:173058189-173058269 ( 2) CTCCATGA 1 chr1:41359731-41359811 ( 39) CTCCATGA 1 chr6:140341520-140341600 ( 13) CTCCATGA 1 chr11:106037971-10603805 ( 48) CTCCATTG 1 chr17:58510542-58510622 ( 24) CTCCATGA 1 chr7:123057799-123057879 ( 23) CTCCATGA 1 chr5:2553842-2553922 ( 35) CTCCATTG 1 chr7:76838946-76839026 ( 23) CTCCATGA 1 chr1:184996534-184996614 ( 17) CTCCATGA 1 chr1:75191899-75191979 ( 23) CTCCATGA 1 chr1:93728368-93728448 ( 24) CTCCATGA 1 chr1:189238298-189238378 ( 30) ATCCATGG 1 chr4:65096586-65096666 ( 6) ATCCATGG 1 chr19:22130731-22130811 ( 70) ATCCATGG 1 chr19:22327353-22327433 ( 67) ATCCATGG 1 chr9:35142214-35142294 ( 45) CTTCATGG 1 chr6:2710846-2710926 ( 44) CTCCTTGG 1 chr2:214340314-214340394 ( 28) CCCCATGA 1 chr8:37850646-37850726 ( 31) CCCCATGA 1 chr15:75434979-75435059 ( 3) ACCCATGG 1 chr5:64525846-64525926 ( 15) CTCCATAG 1 chr7:46508523-46508603 ( 27) ACCCATGG 1 chr7:1724785-1724865 ( 10) CTCCATAG 1 chr9:11269184-11269264 ( 28) ACCCATGG 1 chr1:55109550-55109630 ( 21) CTCCATAG 1 chr19:23128522-23128602 ( 44) ACCCATGG 1 chr6:142534691-142534771 ( 21) TTCCATGA 1 chr1:181254254-181254334 ( 3) TTCCATTG 1 chr1:61049514-61049594 ( 25) TTCCATTG 1 chr2:125831173-125831253 ( 37) TTCCATTG 1 chr8:8293293-8293373 ( 16) TTCCATTG 1 chr7:33110066-33110146 ( 29) CCTCATGG 1 chr16:53219817-53219897 ( 59) CCTCATGG 1 chr4:68526297-68526377 ( 45) CCTCATGG 1 chr4:26681066-26681146 ( 65) CCTCATGG 1 chr6:161404591-161404671 ( 34) CCTCATGG 1 chr12:57258260-57258340 ( 57) CCTCATGG 1 chr17:37980070-37980150 ( 54) CCTCATGG 1 chr7:96342512-96342592 ( 51) CCTCATGG 1 chr6:68666387-68666467 ( 60) CCTCATGG 1 chr4:75522547-75522627 ( 46) CCTCATGG 1 chr6:20943418-20943498 ( 11) CTCCATTA 1 chr12:51310238-51310318 ( 41) ATCCATTG 1 chr2:72613587-72613667 ( 40) TTTCATGG 1 chr11:114458262-11445834 ( 30) ATCCATTG 1 chr2:41722327-41722407 ( 45) ATCCATGA 1 chr11:43805994-43806074 ( 59) CCCCTTGG 1 chr17:66328264-66328344 ( 59) CCCCTTGG 1 chr6:159390345-159390425 ( 35) CTTCATGA 1 chr19:51905536-51905616 ( 13) CTTCATTG 1 chr16:67524784-67524864 ( 54) TTCCTTGG 1 chr10:125989457-12598953 ( 50) TTCCTTGG 1 chr9:96655221-96655301 ( 46) TTCCTTGG 1 chr12:47947165-47947245 ( 33) TTCCTTGG 1 chr5:79538807-79538887 ( 57) TTCCTTGG 1 chr10:37611561-37611641 ( 34) TCCCATTG 1 chr11:44047429-44047509 ( 3) TTCCATAG 1 chr19:8917512-8917592 ( 20) TTCCATAG 1 chr10:91896630-91896710 ( 52) TTCCATAG 1 chr2:158232046-158232126 ( 27) CTCCTTGA 1 chr21:43213082-43213162 ( 15) CTCCTTGA 1 chr12:32059912-32059992 ( 67) ACCCATTG 1 chr6:125432527-125432607 ( 52) TCTCATGG 1 chr17:5713080-5713160 ( 53) ACCCATTG 1 chr8:103689472-103689552 ( 63) TCTCATGG 1 chr3:147599913-147599993 ( 14) ACCCATGA 1 chr6:63362740-63362820 ( 24) ACCCATGA 1 chr7:71252627-71252707 ( 29) ATCCATAG 1 chr5:163754347-163754427 ( 66) ATCCATAG 1 chr2:97096487-97096567 ( 71) CTCCAGGG 1 chr9:132276894-132276974 ( 61) CTCCAGGG 1 chr2:65114889-65114969 ( 44) CCCCTTTG 1 chr1:114906005-114906085 ( 51) CCCCTTTG 1 chr8:140558634-140558714 ( 34) CCCCTTTG 1 chr15:63536040-63536120 ( 44) CTTCATTA 1 chr11:94346448-94346528 ( 59) TTCCTTTG 1 chr1:67533511-67533591 ( 38) CCTCATAG 1 chr4:80180051-80180131 ( 11) TTCCAGGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCCATGG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.02078 E= 2.1e-022 -53 124 -1320 -2 -1320 42 -1320 140 -1320 176 -1320 -43 -1320 207 -1320 -1320 171 -1320 -1320 -79 -1320 -1320 -292 191 -145 -1320 151 -28 -3 -1320 162 -1320 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCCATGG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 94 E= 2.1e-022 0.180851 0.563830 0.000000 0.255319 0.000000 0.319149 0.000000 0.680851 0.000000 0.808511 0.000000 0.191489 0.000000 1.000000 0.000000 0.000000 0.851064 0.000000 0.000000 0.148936 0.000000 0.000000 0.031915 0.968085 0.095745 0.000000 0.691489 0.212766 0.255319 0.000000 0.744681 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCCATGG MEME-3 regular expression -------------------------------------------------------------------------------- [CT][TC]CCAT[GT][GA] -------------------------------------------------------------------------------- Time 11.78 secs. ******************************************************************************** ******************************************************************************** MOTIF TCCAGGCA MEME-4 width = 8 sites = 28 llr = 272 E-value = 8.6e-014 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCCAGGCA MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::a2::a pos.-specific C :7a:::9: probability G :3::8a:: matrix T a:::::1: bits 2.1 * * 1.9 * ** * * 1.7 * ** *** 1.4 * ****** Relative 1.2 ******** Entropy 1.0 ******** (14.0 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCCAGGCA consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCAGGCA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:80710205-80710285 14 1.41e-05 tgcttggatg tccaggca gaagtttact chr16:53219817-53219897 28 1.41e-05 ggcttggatg tccaggca gaagtgtgct chr8:62492875-62492955 58 1.41e-05 tgcttggaca tccaggca attcaataca chr4:26681066-26681146 34 1.41e-05 tgcctggata tccaggca gaagtgtgct chr6:161404591-161404671 3 1.41e-05 tg tccaggca gaagtctgct chr12:57258260-57258340 26 1.41e-05 cacctggatg tccaggca gaattctgat chr13:92079306-92079386 17 1.41e-05 tgcctggatg tccaggca gaagtttgct chr1:67533511-67533591 8 1.41e-05 ctggatg tccaggca gaagtctgct chr4:3382209-3382289 71 1.41e-05 tacttggaca tccaggca tt chr7:96342512-96342592 20 1.41e-05 tgcctggata tccaggca gaagttcact chr6:68666387-68666467 29 1.41e-05 cacctgggta tccaggca gaagtttcct chr3:31648116-31648196 14 1.41e-05 tgcctggatg tccaggca gaagtttgct chr12:28522581-28522661 61 1.41e-05 tgcctcgaca tccaggca tttacctaca chr4:75522547-75522627 15 1.41e-05 tgcctggatg tccaggca gaggtatact chr5:159107257-159107337 16 1.41e-05 cacctggatg tccaggca gaagtttgct chr1:93728368-93728448 67 1.41e-05 tgcttggact tccaggca tttcca chr20:40228626-40228706 25 2.83e-05 atcagacagg tgcaggca gcaccattct chr19:8134402-8134482 56 2.83e-05 CAGTGGGTAT TGCAGGCA AAGGCACAAT chr1:235833637-235833717 9 2.83e-05 cagacgga tgcaggca gcacccttct chr7:133640142-133640222 40 2.83e-05 agctcctctc tgcaggca ggtcatcctg chr4:68526297-68526377 14 5.86e-05 cacctggatg tccaggta gaagtttact chr13:109258934-10925901 19 5.86e-05 tgcctggata tccaggta gaagtctgct chr4:151879286-151879366 67 5.86e-05 tgcctggaca tccaggta ttttca chr7:46508523-46508603 11 7.39e-05 tgtccatgga tgcaagca tgaccttcac chr21:34739894-34739974 11 7.39e-05 ggtgtgctct tgcaagca gatggacaca chr9:11269184-11269264 12 7.39e-05 tgtccacgga tgcaagca tcaccttcac chr4:65096586-65096666 15 7.39e-05 catccatgga tgcaagca tgaccttcac chr8:142994843-142994923 45 7.39e-05 ttggaaacaa tgcaagca agaaggcagt -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCAGGCA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:80710205-80710285 1.4e-05 13_[+4]_59 chr16:53219817-53219897 1.4e-05 27_[+4]_45 chr8:62492875-62492955 1.4e-05 57_[+4]_15 chr4:26681066-26681146 1.4e-05 33_[+4]_39 chr6:161404591-161404671 1.4e-05 2_[+4]_70 chr12:57258260-57258340 1.4e-05 25_[+4]_47 chr13:92079306-92079386 1.4e-05 16_[+4]_56 chr1:67533511-67533591 1.4e-05 7_[+4]_65 chr4:3382209-3382289 1.4e-05 70_[+4]_2 chr7:96342512-96342592 1.4e-05 19_[+4]_53 chr6:68666387-68666467 1.4e-05 28_[+4]_44 chr3:31648116-31648196 1.4e-05 13_[+4]_59 chr12:28522581-28522661 1.4e-05 60_[+4]_12 chr4:75522547-75522627 1.4e-05 14_[+4]_58 chr5:159107257-159107337 1.4e-05 15_[+4]_57 chr1:93728368-93728448 1.4e-05 66_[+4]_6 chr20:40228626-40228706 2.8e-05 24_[+4]_48 chr19:8134402-8134482 2.8e-05 55_[+4]_17 chr1:235833637-235833717 2.8e-05 8_[+4]_64 chr7:133640142-133640222 2.8e-05 39_[+4]_33 chr4:68526297-68526377 5.9e-05 13_[+4]_59 chr13:109258934-10925901 5.9e-05 18_[+4]_54 chr4:151879286-151879366 5.9e-05 66_[+4]_6 chr7:46508523-46508603 7.4e-05 10_[+4]_62 chr21:34739894-34739974 7.4e-05 10_[+4]_62 chr9:11269184-11269264 7.4e-05 11_[+4]_61 chr4:65096586-65096666 7.4e-05 14_[+4]_58 chr8:142994843-142994923 7.4e-05 44_[+4]_28 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCAGGCA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCCAGGCA width=8 seqs=28 chr4:80710205-80710285 ( 14) TCCAGGCA 1 chr16:53219817-53219897 ( 28) TCCAGGCA 1 chr8:62492875-62492955 ( 58) TCCAGGCA 1 chr4:26681066-26681146 ( 34) TCCAGGCA 1 chr6:161404591-161404671 ( 3) TCCAGGCA 1 chr12:57258260-57258340 ( 26) TCCAGGCA 1 chr13:92079306-92079386 ( 17) TCCAGGCA 1 chr1:67533511-67533591 ( 8) TCCAGGCA 1 chr4:3382209-3382289 ( 71) TCCAGGCA 1 chr7:96342512-96342592 ( 20) TCCAGGCA 1 chr6:68666387-68666467 ( 29) TCCAGGCA 1 chr3:31648116-31648196 ( 14) TCCAGGCA 1 chr12:28522581-28522661 ( 61) TCCAGGCA 1 chr4:75522547-75522627 ( 15) TCCAGGCA 1 chr5:159107257-159107337 ( 16) TCCAGGCA 1 chr1:93728368-93728448 ( 67) TCCAGGCA 1 chr20:40228626-40228706 ( 25) TGCAGGCA 1 chr19:8134402-8134482 ( 56) TGCAGGCA 1 chr1:235833637-235833717 ( 9) TGCAGGCA 1 chr7:133640142-133640222 ( 40) TGCAGGCA 1 chr4:68526297-68526377 ( 14) TCCAGGTA 1 chr13:109258934-10925901 ( 19) TCCAGGTA 1 chr4:151879286-151879366 ( 67) TCCAGGTA 1 chr7:46508523-46508603 ( 11) TGCAAGCA 1 chr21:34739894-34739974 ( 11) TGCAAGCA 1 chr9:11269184-11269264 ( 12) TGCAAGCA 1 chr4:65096586-65096666 ( 15) TGCAAGCA 1 chr8:142994843-142994923 ( 45) TGCAAGCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCAGGCA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.95252 E= 8.6e-014 -1145 -1145 -1145 195 -1145 151 41 -1145 -1145 207 -1145 -1145 194 -1145 -1145 -1145 -55 -1145 176 -1145 -1145 -1145 205 -1145 -1145 190 -1145 -127 194 -1145 -1145 -1145 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCAGGCA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 28 E= 8.6e-014 0.000000 0.000000 0.000000 1.000000 0.000000 0.678571 0.321429 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.178571 0.000000 0.821429 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.892857 0.000000 0.107143 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCCAGGCA MEME-4 regular expression -------------------------------------------------------------------------------- T[CG]CAGGCA -------------------------------------------------------------------------------- Time 14.94 secs. ******************************************************************************** ******************************************************************************** MOTIF GGCTCCAC MEME-5 width = 8 sites = 20 llr = 208 E-value = 1.3e-010 ******************************************************************************** -------------------------------------------------------------------------------- Motif GGCTCCAC MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::::::9: pos.-specific C ::a1aa:9 probability G aa:::::: matrix T :::a::11 bits 2.1 *** ** 1.9 *** ** 1.7 ****** * 1.4 ******** Relative 1.2 ******** Entropy 1.0 ******** (15.0 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GGCTCCAC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGCTCCAC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:120096888-120096968 50 1.29e-05 tctacatgag ggctccac tcctgcagca chr6:142534691-142534771 30 1.29e-05 gttccatgag ggctccac cagtgcagca chr15:90922658-90922738 18 1.29e-05 tctctgtgaa ggctccac ccctgcagca chr8:62492875-62492955 24 1.29e-05 tctccatgag ggctccac ccgtacagca chr1:89084159-89084239 21 1.29e-05 tctccatgag ggctccac ccctgcagca chr6:140341520-140341600 22 1.29e-05 tctccatgag ggctccac ccgtgcagca chr8:37850646-37850726 40 1.29e-05 tccccatgag ggctccac ccctgcagca chr17:58510542-58510622 33 1.29e-05 tctccatgag ggctccac ccctacagca chr4:151879286-151879366 33 1.29e-05 tctctgtgag ggctccac ccctgcagca chr4:75209883-75209963 40 1.29e-05 tctctgtgtg ggctccac cctggcagca chr2:158232046-158232126 36 1.29e-05 tctccttgag ggctccac ctacccagta chr11:74538113-74538193 18 1.29e-05 aggtgctcca ggctccac cgctgcagca chr7:76838946-76839026 32 1.29e-05 tctccatgag ggctccac cctggcatca chr1:184996534-184996614 26 1.29e-05 tctccatgag ggctccac ccctgcagta chr1:93728368-93728448 33 1.29e-05 tctccatgag ggctccac ctccacagca chr6:137153194-137153274 24 2.56e-05 tctccatgag ggctcctc ccttgcagca chr12:28522581-28522661 27 2.56e-05 tctctgtgag ggctcctc ctctgtagca chr7:123057799-123057879 32 3.95e-05 cctccatgag ggctccat ccctgcagta chr1:75191899-75191979 32 3.95e-05 tctccatgag ggctccat ccctgcagca chr4:3382209-3382289 37 5.14e-05 tctgcacgag ggccccac ccctgcagct -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGCTCCAC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:120096888-120096968 1.3e-05 49_[+5]_23 chr6:142534691-142534771 1.3e-05 29_[+5]_43 chr15:90922658-90922738 1.3e-05 17_[+5]_55 chr8:62492875-62492955 1.3e-05 23_[+5]_49 chr1:89084159-89084239 1.3e-05 20_[+5]_52 chr6:140341520-140341600 1.3e-05 21_[+5]_51 chr8:37850646-37850726 1.3e-05 39_[+5]_33 chr17:58510542-58510622 1.3e-05 32_[+5]_40 chr4:151879286-151879366 1.3e-05 32_[+5]_40 chr4:75209883-75209963 1.3e-05 39_[+5]_33 chr2:158232046-158232126 1.3e-05 35_[+5]_37 chr11:74538113-74538193 1.3e-05 17_[+5]_55 chr7:76838946-76839026 1.3e-05 31_[+5]_41 chr1:184996534-184996614 1.3e-05 25_[+5]_47 chr1:93728368-93728448 1.3e-05 32_[+5]_40 chr6:137153194-137153274 2.6e-05 23_[+5]_49 chr12:28522581-28522661 2.6e-05 26_[+5]_46 chr7:123057799-123057879 3.9e-05 31_[+5]_41 chr1:75191899-75191979 3.9e-05 31_[+5]_41 chr4:3382209-3382289 5.1e-05 36_[+5]_36 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGCTCCAC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GGCTCCAC width=8 seqs=20 chr7:120096888-120096968 ( 50) GGCTCCAC 1 chr6:142534691-142534771 ( 30) GGCTCCAC 1 chr15:90922658-90922738 ( 18) GGCTCCAC 1 chr8:62492875-62492955 ( 24) GGCTCCAC 1 chr1:89084159-89084239 ( 21) GGCTCCAC 1 chr6:140341520-140341600 ( 22) GGCTCCAC 1 chr8:37850646-37850726 ( 40) GGCTCCAC 1 chr17:58510542-58510622 ( 33) GGCTCCAC 1 chr4:151879286-151879366 ( 33) GGCTCCAC 1 chr4:75209883-75209963 ( 40) GGCTCCAC 1 chr2:158232046-158232126 ( 36) GGCTCCAC 1 chr11:74538113-74538193 ( 18) GGCTCCAC 1 chr7:76838946-76839026 ( 32) GGCTCCAC 1 chr1:184996534-184996614 ( 26) GGCTCCAC 1 chr1:93728368-93728448 ( 33) GGCTCCAC 1 chr6:137153194-137153274 ( 24) GGCTCCTC 1 chr12:28522581-28522661 ( 27) GGCTCCTC 1 chr7:123057799-123057879 ( 32) GGCTCCAT 1 chr1:75191899-75191979 ( 32) GGCTCCAT 1 chr4:3382209-3382289 ( 37) GGCCCCAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGCTCCAC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0839 E= 1.3e-010 -1097 -1097 205 -1097 -1097 -1097 205 -1097 -1097 206 -1097 -1097 -1097 -225 -1097 188 -1097 206 -1097 -1097 -1097 206 -1097 -1097 179 -1097 -1097 -137 -1097 191 -1097 -137 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGCTCCAC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 20 E= 1.3e-010 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.050000 0.000000 0.950000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.900000 0.000000 0.000000 0.100000 0.000000 0.900000 0.000000 0.100000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGCTCCAC MEME-5 regular expression -------------------------------------------------------------------------------- GGCTCCAC -------------------------------------------------------------------------------- Time 18.10 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:105336101-105336181 1.68e-03 31_[+1(2.94e-05)]_41 chr5:79538807-79538887 7.04e-04 32_[+1(2.94e-05)]_40 chr1:93728368-93728448 9.12e-09 23_[+3(7.15e-05)]_1_[+5(1.29e-05)]_\ 16_[+2(7.10e-05)]_2_[+4(1.41e-05)]_6 chr8:124679841-124679921 1.47e-01 80 chr4:116936376-116936456 7.21e-01 80 chr1:75191899-75191979 1.29e-07 22_[+3(7.15e-05)]_1_[+5(3.95e-05)]_\ 2_[+1(2.94e-05)]_6_[+2(1.41e-05)]_17 chr1:246693933-246694013 3.05e-02 50_[+3(4.18e-05)]_22 chr2:78256674-78256754 6.37e-02 80 chr11:57386949-57387029 2.92e-03 66_[+3(2.68e-05)]_6 chr12:47947165-47947245 6.25e-04 8_[+1(2.94e-05)]_64 chr4:187373303-187373383 7.74e-01 80 chr6:132244670-132244750 3.19e-01 80 chr19:23128522-23128602 1.98e-04 68_[+3(8.67e-05)]_4 chr15:63536040-63536120 1.35e-01 80 chr8:131841316-131841396 2.65e-03 39_[+3(4.18e-05)]_33 chr9:132276894-132276974 4.33e-03 80 chr7:106470114-106470194 8.73e-02 80 chr21:15791393-15791473 5.43e-02 53_[+1(5.90e-05)]_19 chr5:159107257-159107337 8.48e-04 15_[+4(1.41e-05)]_57 chr20:54775669-54775749 2.00e-01 80 chr8:102768655-102768735 2.87e-01 80 chr1:43053582-43053662 4.84e-01 80 chr4:56441838-56441918 1.07e-01 57_[+1(5.90e-05)]_15 chr2:173390451-173390531 5.16e-01 80 chr3:71540474-71540554 1.97e-01 80 chr7:140724627-140724707 8.06e-02 80 chr7:99548586-99548666 4.45e-02 10_[+1(2.94e-05)]_62 chr8:127616238-127616318 4.31e-01 80 chr2:183912664-183912744 5.69e-02 80 chr1:184996534-184996614 3.31e-08 16_[+3(7.15e-05)]_1_[+5(1.29e-05)]_\ 16_[+2(1.41e-05)]_23 chr1:212032898-212032978 6.76e-02 80 chr7:76838946-76839026 2.97e-07 22_[+3(7.15e-05)]_1_[+5(1.29e-05)]_\ 16_[+2(1.41e-05)]_17 chr7:97091080-97091160 4.66e-01 80 chr6:63362740-63362820 3.51e-02 80 chr11:74538113-74538193 2.42e-07 17_[+5(1.29e-05)]_2_[+1(2.94e-05)]_\ 6_[+2(1.41e-05)]_31 chr21:43213082-43213162 1.42e-01 80 chr19:22327353-22327433 2.92e-02 66_[+3(8.67e-05)]_6 chr2:69128859-69128939 6.73e-02 43_[+1(5.90e-05)]_29 chr8:8293293-8293373 1.19e-01 80 chr5:155221980-155222060 1.74e-02 80 chr18:8929498-8929578 3.66e-01 80 chr5:2553842-2553922 1.08e-02 34_[+3(7.15e-05)]_38 chr2:158232046-158232126 1.32e-05 35_[+5(1.29e-05)]_16_[+2(1.41e-05)]_\ 13 chr9:128771491-128771571 3.32e-01 80 chr21:34581010-34581090 2.51e-02 80 chr19:5515904-5515984 1.81e-01 80 chr11:70788861-70788941 1.68e-01 80 chr2:8699249-8699329 7.75e-02 37_[+1(5.90e-05)]_35 chr6:167219850-167219930 1.85e-01 80 chr12:124426492-12442657 3.20e-04 36_[+1(1.53e-05)]_36 chr2:151003567-151003647 3.51e-01 80 chr8:142994843-142994923 1.16e-01 44_[+4(7.39e-05)]_28 chr4:75209883-75209963 2.09e-05 39_[+5(1.29e-05)]_16_[+2(1.41e-05)]_\ 9 chr3:147599913-147599993 7.96e-02 80 chr2:125831173-125831253 1.76e-02 80 chr7:123057799-123057879 3.76e-07 22_[+3(7.15e-05)]_1_[+5(3.95e-05)]_\ 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51_[+3(4.18e-05)]_21 chr12:32059912-32059992 2.75e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n07.farnam.hpc.yale.internal ********************************************************************************