******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/CBFA2T3.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr19:381064-381144 1.0000 80 chr14:88491087-88491167 1.0000 80 chr6:10750103-10750183 1.0000 80 chr7:7082284-7082364 1.0000 80 chr6:160992404-160992484 1.0000 80 chr8:144016040-144016120 1.0000 80 chr17:62919226-62919306 1.0000 80 chr12:27170378-27170458 1.0000 80 chr11:124537653-12453773 1.0000 80 chr14:35122449-35122529 1.0000 80 chr1:224058441-224058521 1.0000 80 chr1:211395919-211395999 1.0000 80 chr4:144940562-144940642 1.0000 80 chr14:23366712-23366792 1.0000 80 chr1:25611725-25611805 1.0000 80 chrX:47535543-47535623 1.0000 80 chr3:14162506-14162586 1.0000 80 chr20:33780333-33780413 1.0000 80 chr19:516716-516796 1.0000 80 chr10:7049687-7049767 1.0000 80 chr2:208825012-208825092 1.0000 80 chr1:160919166-160919246 1.0000 80 chr11:62136574-62136654 1.0000 80 chrX:79767986-79768066 1.0000 80 chr14:36733971-36734051 1.0000 80 chr4:99722527-99722607 1.0000 80 chr3:57584942-57585022 1.0000 80 chr5:139990841-139990921 1.0000 80 chr1:25606345-25606425 1.0000 80 chr9:69491642-69491722 1.0000 80 chr7:5123118-5123198 1.0000 80 chr3:177148569-177148649 1.0000 80 chr8:38068319-38068399 1.0000 80 chr1:191793077-191793157 1.0000 80 chr5:134528296-134528376 1.0000 80 chr3:32115899-32115979 1.0000 80 chr19:35411451-35411531 1.0000 80 chr9:136159295-136159375 1.0000 80 chr5:176075746-176075826 1.0000 80 chr4:1884777-1884857 1.0000 80 chr1:6489893-6489973 1.0000 80 chr1:207020985-207021065 1.0000 80 chr4:68418029-68418109 1.0000 80 chr10:43142681-43142761 1.0000 80 chr20:9129847-9129927 1.0000 80 chr4:144826768-144826848 1.0000 80 chr2:240008152-240008232 1.0000 80 chr11:61109833-61109913 1.0000 80 chr17:62971009-62971089 1.0000 80 chr1:228608967-228609047 1.0000 80 chr6:159303106-159303186 1.0000 80 chr2:158755887-158755967 1.0000 80 chr12:53703911-53703991 1.0000 80 chr9:132875219-132875299 1.0000 80 chr16:9171927-9172007 1.0000 80 chr8:2645844-2645924 1.0000 80 chr14:24725570-24725650 1.0000 80 chr7:77502865-77502945 1.0000 80 chr14:20645709-20645789 1.0000 80 chr11:2000372-2000452 1.0000 80 chrX:47572287-47572367 1.0000 80 chr8:37949364-37949444 1.0000 80 chr15:39432311-39432391 1.0000 80 chr10:43140678-43140758 1.0000 80 chr11:118306980-11830706 1.0000 80 chr12:28345242-28345322 1.0000 80 chr7:139935090-139935170 1.0000 80 chr5:175624414-175624494 1.0000 80 chr1:65487638-65487718 1.0000 80 chr8:37939615-37939695 1.0000 80 chr4:140364982-140365062 1.0000 80 chr14:100038918-10003899 1.0000 80 chr13:19398967-19399047 1.0000 80 chr9:125209218-125209298 1.0000 80 chr1:151687984-151688064 1.0000 80 chr15:75987015-75987095 1.0000 80 chr9:102907620-102907700 1.0000 80 chr13:50420835-50420915 1.0000 80 chr16:10437118-10437198 1.0000 80 chr6:80314384-80314464 1.0000 80 chr5:32288424-32288504 1.0000 80 chr7:24903973-24904053 1.0000 80 chr1:95581314-95581394 1.0000 80 chr4:145000047-145000127 1.0000 80 chr3:6582803-6582883 1.0000 80 chr6:129984391-129984471 1.0000 80 chr16:10591143-10591223 1.0000 80 chr1:25739906-25739986 1.0000 80 chr2:128300692-128300772 1.0000 80 chr20:30505819-30505899 1.0000 80 chr16:21548249-21548329 1.0000 80 chr2:30736590-30736670 1.0000 80 chr9:4862954-4863034 1.0000 80 chr2:239331042-239331122 1.0000 80 chr9:128239615-128239695 1.0000 80 chr10:13747877-13747957 1.0000 80 chrX:55054624-55054704 1.0000 80 chr3:196715536-196715616 1.0000 80 chr1:63156058-63156138 1.0000 80 chr4:103277041-103277121 1.0000 80 chr6:16263876-16263956 1.0000 80 chr5:657864-657944 1.0000 80 chr6:10725441-10725521 1.0000 80 chr3:125152084-125152164 1.0000 80 chr4:25052509-25052589 1.0000 80 chr9:131355491-131355571 1.0000 80 chr20:3890846-3890926 1.0000 80 chr17:73444681-73444761 1.0000 80 chr15:74902916-74902996 1.0000 80 chr17:19913648-19913728 1.0000 80 chr17:14064888-14064968 1.0000 80 chr6:112126190-112126270 1.0000 80 chr3:129512900-129512980 1.0000 80 chr4:145061885-145061965 1.0000 80 chr1:28851661-28851741 1.0000 80 chr8:98790786-98790866 1.0000 80 chr17:26854455-26854535 1.0000 80 chr5:29796336-29796416 1.0000 80 chr2:58916117-58916197 1.0000 80 chr13:95923463-95923543 1.0000 80 chr19:53195821-53195901 1.0000 80 chr4:154449959-154450039 1.0000 80 chr7:157195944-157196024 1.0000 80 chr8:103393669-103393749 1.0000 80 chr3:143002405-143002485 1.0000 80 chr11:71706834-71706914 1.0000 80 chr3:128773654-128773734 1.0000 80 chr2:169990978-169991058 1.0000 80 chr7:140091606-140091686 1.0000 80 chr17:31298382-31298462 1.0000 80 chr13:44956976-44957056 1.0000 80 chr10:63540228-63540308 1.0000 80 chr10:19024850-19024930 1.0000 80 chrX:47543021-47543101 1.0000 80 chr7:43026534-43026614 1.0000 80 chr2:173465564-173465644 1.0000 80 chr4:69730317-69730397 1.0000 80 chr7:127478999-127479079 1.0000 80 chr5:71462351-71462431 1.0000 80 chr11:876095-876175 1.0000 80 chrX:153119183-153119263 1.0000 80 chr4:144775941-144776021 1.0000 80 chr4:84417384-84417464 1.0000 80 chr11:16878928-16879008 1.0000 80 chr7:72176125-72176205 1.0000 80 chr15:31270658-31270738 1.0000 80 chr12:108879357-10887943 1.0000 80 chr14:103844525-10384460 1.0000 80 chrX:107801626-107801706 1.0000 80 chr14:61456501-61456581 1.0000 80 chr7:39849955-39850035 1.0000 80 chr11:5617995-5618075 1.0000 80 chr1:35602539-35602619 1.0000 80 chr9:101130845-101130925 1.0000 80 chr13:44972142-44972222 1.0000 80 chr7:99320990-99321070 1.0000 80 chr1:95100702-95100782 1.0000 80 chr1:156430435-156430515 1.0000 80 chr9:101338780-101338860 1.0000 80 chr15:69284230-69284310 1.0000 80 chr18:43733358-43733438 1.0000 80 chrX:49100809-49100889 1.0000 80 chr10:72318683-72318763 1.0000 80 chr2:227700194-227700274 1.0000 80 chr16:21272958-21273038 1.0000 80 chr12:125369547-12536962 1.0000 80 chr1:65696954-65697034 1.0000 80 chr5:153753465-153753545 1.0000 80 chr19:6682880-6682960 1.0000 80 chr20:37192598-37192678 1.0000 80 chr20:32007083-32007163 1.0000 80 chr7:765369-765449 1.0000 80 chr1:70005902-70005982 1.0000 80 chr20:48715003-48715083 1.0000 80 chr16:25783249-25783329 1.0000 80 chr3:98302759-98302839 1.0000 80 chr5:150845251-150845331 1.0000 80 chr18:67693007-67693087 1.0000 80 chr22:36764684-36764764 1.0000 80 chr11:3900072-3900152 1.0000 80 chr20:42319698-42319778 1.0000 80 chrX:102356741-102356821 1.0000 80 chr6:27741820-27741900 1.0000 80 chr11:34258293-34258373 1.0000 80 chr9:7067332-7067412 1.0000 80 chr1:27118210-27118290 1.0000 80 chr6:142337967-142338047 1.0000 80 chr1:243269310-243269390 1.0000 80 chr19:51727514-51727594 1.0000 80 chr11:2324971-2325051 1.0000 80 chr1:207809096-207809176 1.0000 80 chr2:32705198-32705278 1.0000 80 chr13:44961227-44961307 1.0000 80 chr19:38613546-38613626 1.0000 80 chr6:13381105-13381185 1.0000 80 chr15:40851727-40851807 1.0000 80 chr21:47875773-47875853 1.0000 80 chr16:23678669-23678749 1.0000 80 chr2:127752074-127752154 1.0000 80 chr1:207693585-207693665 1.0000 80 chrX:55041559-55041639 1.0000 80 chrX:134996744-134996824 1.0000 80 chr19:14502092-14502172 1.0000 80 chr7:102082194-102082274 1.0000 80 chr10:28783474-28783554 1.0000 80 chr12:9039978-9040058 1.0000 80 chr1:228366650-228366730 1.0000 80 chr16:12387230-12387310 1.0000 80 chr3:101249330-101249410 1.0000 80 chr13:25926488-25926568 1.0000 80 chr21:40357697-40357777 1.0000 80 chr8:23366398-23366478 1.0000 80 chr16:56323922-56324002 1.0000 80 chr3:141567989-141568069 1.0000 80 chr6:34249867-34249947 1.0000 80 chr4:144896854-144896934 1.0000 80 chr7:100909442-100909522 1.0000 80 chr11:57415825-57415905 1.0000 80 chr7:158628231-158628311 1.0000 80 chr17:61498033-61498113 1.0000 80 chr17:26295374-26295454 1.0000 80 chr2:209436645-209436725 1.0000 80 chr5:37576381-37576461 1.0000 80 chr15:35459068-35459148 1.0000 80 chr1:186015755-186015835 1.0000 80 chr7:104607698-104607778 1.0000 80 chr15:88214703-88214783 1.0000 80 chr15:69276649-69276729 1.0000 80 chr1:109677197-109677277 1.0000 80 chr2:74469931-74470011 1.0000 80 chr1:35309349-35309429 1.0000 80 chr13:39573070-39573150 1.0000 80 chr1:226298957-226299037 1.0000 80 chr11:16626424-16626504 1.0000 80 chr7:44120936-44121016 1.0000 80 chr8:66655618-66655698 1.0000 80 chr10:75004827-75004907 1.0000 80 chr5:42873109-42873189 1.0000 80 chr11:62645227-62645307 1.0000 80 chr18:77361330-77361410 1.0000 80 chr16:66651872-66651952 1.0000 80 chr9:100987560-100987640 1.0000 80 chr5:16418757-16418837 1.0000 80 chr1:207191103-207191183 1.0000 80 chr8:101776304-101776384 1.0000 80 chr1:16380765-16380845 1.0000 80 chr3:138941040-138941120 1.0000 80 chr3:171164795-171164875 1.0000 80 chr17:52938595-52938675 1.0000 80 chr2:122292306-122292386 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_CBFA2T3/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/CBFA2T3.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.247 C 0.242 G 0.251 T 0.261 Background letter frequencies (from file dataset with add-one prior applied): A 0.247 C 0.242 G 0.251 T 0.261 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF AGATAAGV MEME-1 width = 8 sites = 127 llr = 872 E-value = 2.2e-046 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGATAAGV MEME-1 Description -------------------------------------------------------------------------------- Simplified A 7:a:8724 pos.-specific C ::::::22 probability G :a::1363 matrix T 3::a1::1 bits 2.0 ** 1.8 *** 1.6 *** 1.4 *** Relative 1.2 *** * Entropy 1.0 ****** (9.9 bits) 0.8 ****** 0.6 ******* 0.4 ******* 0.2 ******** 0.0 -------- Multilevel AGATAAGA consensus T GAG sequence CC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGV MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr15:35459068-35459148 47 1.51e-05 AGCTTAAGAG AGATAAGA CATGACTTTG chr1:35602539-35602619 34 1.51e-05 tggggcaaag agataaga ggttggggca chr15:31270658-31270738 2 1.51e-05 T AGATAAGA GAAACTAGTA chr7:43026534-43026614 16 1.51e-05 GTGGAAAAAA AGATAAGA CTGGTGAGAG chr6:16263876-16263956 14 1.51e-05 tggggtgcag agataaga ggtcagggca chr9:102907620-102907700 12 1.51e-05 cagggcgcag agataaga ggttggggcg chr9:69491642-69491722 27 1.51e-05 tttgcagttg agataaga ggaaggcatc chr14:88491087-88491167 70 1.51e-05 tttgcagttg agataaga gga chr8:101776304-101776384 6 3.05e-05 CAGTG AGATAAGG CAAGAACATG chr2:74469931-74470011 35 3.05e-05 tttttagtag agataagg tttcaccatg chr7:104607698-104607778 16 3.05e-05 TGGGCTGAGT AGATAAGG CAAGCTGGGA chr13:25926488-25926568 1 3.05e-05 . agataagg agaaaagagg chrX:102356741-102356821 17 3.05e-05 gggtacacta agataagg aagctaaaag chr13:44956976-44957056 13 3.05e-05 tgggagaggc agataagg aagctgtcag chr17:26854455-26854535 31 3.05e-05 CAGGATAGGC AGATAAGG ACAGCAGGGC chr9:128239615-128239695 72 3.05e-05 TTGGACAAAG AGATAAGG G chr16:21548249-21548329 37 3.05e-05 GCTTTCCCCG AGATAAGG CCATGAGGCC chr13:19398967-19399047 25 3.05e-05 agttaagtgc agataagg gaacctggac chrX:47572287-47572367 64 3.05e-05 aggtgcacta agataagg aagctaaaa chr14:23366712-23366792 18 3.05e-05 AGCTGCTTCA AGATAAGG TCTGAGGCTG chr12:9039978-9040058 50 4.53e-05 gtcacaagat agataagc atgagtcgca chr11:876095-876175 70 4.53e-05 GTGCAAGGAC AGATAAGC CTC chr16:10437118-10437198 42 4.53e-05 gaaggtccca agataagc ctgagcaaac chr11:62645227-62645307 60 6.13e-05 aggtggtggc tgataaga ttggagaggc chr1:109677197-109677277 22 6.13e-05 GTTGGCCTAC TGATAAGA AACCGTGGCT chr11:2324971-2325051 54 6.13e-05 AGGTCCAGAC TGATAAGA TTACAGCTCC chrX:107801626-107801706 27 6.13e-05 GTAAAGGTGC TGATAAGA TATGATGGGT chr1:25739906-25739986 65 6.13e-05 TGTTCAGGGG TGATAAGA AGTGGATG chr15:39432311-39432391 7 6.13e-05 CTGCAG TGATAAGA GCACAGCTGT chr1:207020985-207021065 54 6.13e-05 cttgtcaccc tgataaga atgacacagg chr7:44120936-44121016 17 9.07e-05 tgtaaagcag agataaca tatccaccct chr1:207693585-207693665 48 9.07e-05 tgggacagct agataaaa cctacttgac chr22:36764684-36764764 13 9.07e-05 AATTTCTCTA AGATAACA GTGCTGGGAG chr19:6682880-6682960 16 9.07e-05 tggccaacaa agataaaa atgcagcaaa chr11:5617995-5618075 8 9.07e-05 TGAGTTT AGATAAAA GCCGAGTGAG chr7:39849955-39850035 31 9.07e-05 CACATGGGCC AGATAACA CAGCACAGCT chr2:58916117-58916197 21 9.07e-05 agggccttat agataaaa ctcctatctc chr16:9171927-9172007 1 9.07e-05 . agataaaa gattgtgggc chr1:207191103-207191183 20 1.22e-04 TGGCAAGTGG TGATAAGG ACAACAATCC chr3:141567989-141568069 69 1.22e-04 AGGCAGAAGC TGATAagg agaa chrX:55041559-55041639 67 1.22e-04 TGCTGCTTTG AGATAGGA CTTTCA chr5:150845251-150845331 67 1.22e-04 CGCACATGAG AGATAGGA GCAAAG chr16:25783249-25783329 31 1.22e-04 ATTTAGTGGA AGATAGGA TAACGTTTCT chr8:2645844-2645924 51 1.22e-04 ccagctctgg agatagga agacaggttc chr20:42319698-42319778 23 1.52e-04 ctgaccttcc agataaag aaaccaaggc chr10:63540228-63540308 46 1.52e-04 GGCCTCCACT AGATAAAG ACATCTGGAT chr17:19913648-19913728 22 1.52e-04 TGCAGGCAGC AGATAAAG TGTTTTTTGA chrX:55054624-55054704 9 1.52e-04 CAGACCAC AGATAAAG TTGCCAGAGT chr6:159303106-159303186 73 1.52e-04 tgggttctgg agataaag chr1:70005902-70005982 42 1.68e-04 GTGAGGACTA AGATAGGG TCGAGTTATC chr7:72176125-72176205 24 1.68e-04 aggtgcacta agataggg aggctaaaag chr4:154449959-154450039 17 1.68e-04 TGTGGGCCAC AGATAGGG TAGACTTTGA chr17:14064888-14064968 12 1.68e-04 tgagtggagt agataggg aagatttgcc chrX:47535543-47535623 44 1.68e-04 aggtgcacta agataggg aagctaaaag chr17:52938595-52938675 27 1.84e-04 CTGCCTTAAC TGATAAGC CTATGAATGG chr14:35122449-35122529 60 1.84e-04 tttgcattac tgataagc cctctatcat chr19:381064-381144 71 1.84e-04 CCGTGGTGAT TGATAAGC AG chr21:47875773-47875853 70 2.12e-04 tgtggaagag agataacc aat chr11:34258293-34258373 4 2.12e-04 GGT AGATAAAC GAAATCGCAT chr5:29796336-29796416 44 2.12e-04 AGTTGAATAA AGATAACC TGGACCACCA chr9:4862954-4863034 53 2.12e-04 TTTTTTAGGC AGATAAAC CTGTGAACTT chr5:32288424-32288504 31 2.12e-04 cctttgtctg agataaac tctgcactgc chr4:140364982-140365062 13 2.12e-04 ttgtcggagg agataaac cctacactgc chr6:10725441-10725521 60 2.43e-04 CTTTATCTAC AGATAGGC AGGGGCGGTT chr4:103277041-103277121 34 2.43e-04 CTGGAGAGTA AGATTAGA AAAATGGGAC chr2:239331042-239331122 32 2.43e-04 CTGCCAGGAG AGATAGGC CAGCTCCTCC chr16:12387230-12387310 11 2.75e-04 gacccagttc tgATAACA GCAGTGACTG chr8:98790786-98790866 54 2.75e-04 tgtgtccggt tgataaca cccaaagccc chr3:125152084-125152164 12 2.75e-04 tgtgcagtgc tgataaca ccaacgttgc chr11:61109833-61109913 35 2.75e-04 TGTGAGTCCT TGATAAAA ACGATGAGCA chr5:37576381-37576461 23 3.23e-04 gctctttccc agattagg aggtttcact chr1:207809096-207809176 61 3.23e-04 tgggtacttg agattagg gagtggtgat chr4:25052509-25052589 32 3.23e-04 TGTTAGGGTC AGATAAGT CCTGGTTAGG chr3:6582803-6582883 72 3.84e-04 tgccctctcc agatagaa g chr1:65487638-65487718 51 3.84e-04 CGTTAGACTG TGATAAAG GTGACTCAAG chr8:144016040-144016120 2 3.84e-04 T TGATAACG AACTGAGCGT chr8:66655618-66655698 44 4.31e-04 AGTAGAAGAG AGATAGCG AAGGGGAGGA chr21:40357697-40357777 69 4.31e-04 GGGTGTTCAC AGATAGAG CTGG chr1:228366650-228366730 22 4.31e-04 tgctctggcc agatagag gtgggctctg chr1:186015755-186015835 73 4.62e-04 TTTTAACGGT AGATGAGA chr8:103393669-103393749 68 4.62e-04 tcacaattca agatgaga AGCCA chr19:14502092-14502172 17 4.93e-04 ggccaaatcc tgataacc aagtgtatga chr14:24725570-24725650 18 4.93e-04 CCAGCCTGCC TGATAACC AAGTCCCTGA chr7:102082194-102082274 71 5.41e-04 TGCACCTGCT TGATTAGA TT chr5:153753465-153753545 6 5.41e-04 CTCAA TGATTAGA GCCGGCCAGG chr4:145061885-145061965 33 5.41e-04 CATCATCAGC TGATAGGC AGGGGAGGCA chr4:144826768-144826848 22 5.41e-04 CATCATCAGC TGATAGGC AGGGGAGGCA chr4:1884777-1884857 44 5.41e-04 ggataaggag agatgagg ggaagttctg chr4:144940562-144940642 8 5.41e-04 CATCAGC TGATAGGC AGGGGAGGCA chr18:43733358-43733438 62 6.02e-04 TGATGCAGGG AGATAGCC TCCTAACTGC chr3:143002405-143002485 73 6.02e-04 TTGAGTTGCA AGATTAAA chr4:99722527-99722607 6 6.02e-04 GTCAG AGATTACA AACAGTGAGG chr7:24903973-24904053 66 6.52e-04 tgtgcattgc tgataagt tcccggg chr17:62971009-62971089 62 6.52e-04 CTACCTACCT TGATTAGG AAGGAAGGCT chr16:66651872-66651952 4 7.46e-04 TGC TGATAGCA GACAGGTGGG chr7:100909442-100909522 30 7.46e-04 tgttttctgg agattacg tgtaattagt chr20:48715003-48715083 23 7.46e-04 tggaccaggg tgatagca ggaaagtagt chr7:99320990-99321070 29 7.46e-04 tgctgacaat agataact tcctttaact chr5:71462351-71462431 53 7.46e-04 TGGCTCTGTG AGATAACT CCCTTTAGCC chr2:169990978-169991058 60 7.46e-04 cttggtttac tgatagca gttccaccag chr6:80314384-80314464 39 7.46e-04 tgttgggggc agataact tgtcttttta chr3:177148569-177148649 32 7.46e-04 GAGACTGAGG AGATTAAG TGGCTTTCAC chr1:224058441-224058521 1 7.46e-04 . agattaag tctgctgaag chr11:57415825-57415905 55 8.10e-04 TGGAGGCAGA GGATAAGA AGGGAGGTGG chr13:44961227-44961307 66 8.10e-04 ACTGTCACAC AGATAGGT CAACTGC chr12:28345242-28345322 63 8.10e-04 GTGGATGGGT GGATAAGA CTGGTTCCAT chr13:39573070-39573150 9 8.42e-04 gtggggca tgatagag agcctgcctt chr7:158628231-158628311 72 8.42e-04 tgtagataga tgatagag a chr2:158755887-158755967 73 8.42e-04 AGTTTCAGGT TGATAGAG chr3:57584942-57585022 32 8.90e-04 tttgagtttc tgattagc ctctccaaag chr6:27741820-27741900 1 9.50e-04 . agattaac ccctgaccta chr3:129512900-129512980 41 9.50e-04 GCCCAAATTC AGATGACA GCTGCAGTTT chr10:13747877-13747957 32 9.50e-04 TGTTTCAGGC AGATTACC CTGGAGGGCA chr8:38068319-38068399 29 9.50e-04 GAAACCTACC AGATGAAA CTGGATATAA chr4:144896854-144896934 32 9.98e-04 gatactctcc agatggga tagagtttcc chr4:144775941-144776021 42 9.98e-04 gatactctcc agatggga gagagtttcc chr4:145000047-145000127 41 9.98e-04 gatactctcc agatggga gagagtttcc chr3:32115899-32115979 54 9.98e-04 attaccaaac agatggga gcattccaac chr7:5123118-5123198 55 1.09e-03 CGGTTATGTG TGATTACA GTGCCTCTGG chrX:153119183-153119263 31 1.16e-03 tggccatagg ggataagc agccttaaat chr17:73444681-73444761 69 1.16e-03 CAGGCAACGA AGATTAGT CTCA chr12:125369547-12536962 69 1.26e-03 tgggtgggcc tgataact gcat chr1:6489893-6489973 43 1.31e-03 TGGCCTGGAC TGATGAGC TGCCAGCCCC chr3:138941040-138941120 58 1.43e-03 TGCAGCCTCC AGATTGAG GGAGAAATGT chr11:118306980-11830706 71 1.43e-03 GCCGCTATAC AGATTGCG GG chr16:56323922-56324002 8 1.55e-03 gctctca ggataaag ccagccttat chr6:13381105-13381185 44 1.71e-03 ATCTGACCCC AGATTGCC CAGGCTTCCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGV MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr15:35459068-35459148 1.5e-05 46_[+1]_26 chr1:35602539-35602619 1.5e-05 33_[+1]_39 chr15:31270658-31270738 1.5e-05 1_[+1]_71 chr7:43026534-43026614 1.5e-05 15_[+1]_57 chr6:16263876-16263956 1.5e-05 13_[+1]_59 chr9:102907620-102907700 1.5e-05 11_[+1]_61 chr9:69491642-69491722 1.5e-05 26_[+1]_46 chr14:88491087-88491167 1.5e-05 69_[+1]_3 chr8:101776304-101776384 3e-05 5_[+1]_67 chr2:74469931-74470011 3e-05 34_[+1]_38 chr7:104607698-104607778 3e-05 15_[+1]_57 chr13:25926488-25926568 3e-05 [+1]_72 chrX:102356741-102356821 3e-05 16_[+1]_56 chr13:44956976-44957056 3e-05 12_[+1]_60 chr17:26854455-26854535 3e-05 30_[+1]_42 chr9:128239615-128239695 3e-05 71_[+1]_1 chr16:21548249-21548329 3e-05 36_[+1]_36 chr13:19398967-19399047 3e-05 24_[+1]_48 chrX:47572287-47572367 3e-05 63_[+1]_9 chr14:23366712-23366792 3e-05 17_[+1]_55 chr12:9039978-9040058 4.5e-05 49_[+1]_23 chr11:876095-876175 4.5e-05 69_[+1]_3 chr16:10437118-10437198 4.5e-05 41_[+1]_31 chr11:62645227-62645307 6.1e-05 59_[+1]_13 chr1:109677197-109677277 6.1e-05 21_[+1]_51 chr11:2324971-2325051 6.1e-05 53_[+1]_19 chrX:107801626-107801706 6.1e-05 26_[+1]_46 chr1:25739906-25739986 6.1e-05 64_[+1]_8 chr15:39432311-39432391 6.1e-05 6_[+1]_66 chr1:207020985-207021065 6.1e-05 53_[+1]_19 chr7:44120936-44121016 9.1e-05 16_[+1]_56 chr1:207693585-207693665 9.1e-05 47_[+1]_25 chr22:36764684-36764764 9.1e-05 12_[+1]_60 chr19:6682880-6682960 9.1e-05 15_[+1]_57 chr11:5617995-5618075 9.1e-05 7_[+1]_65 chr7:39849955-39850035 9.1e-05 30_[+1]_42 chr2:58916117-58916197 9.1e-05 20_[+1]_52 chr16:9171927-9172007 9.1e-05 [+1]_72 chr1:207191103-207191183 0.00012 19_[+1]_53 chr3:141567989-141568069 0.00012 68_[+1]_4 chrX:55041559-55041639 0.00012 66_[+1]_6 chr5:150845251-150845331 0.00012 66_[+1]_6 chr16:25783249-25783329 0.00012 30_[+1]_42 chr8:2645844-2645924 0.00012 50_[+1]_22 chr20:42319698-42319778 0.00015 22_[+1]_50 chr10:63540228-63540308 0.00015 45_[+1]_27 chr17:19913648-19913728 0.00015 21_[+1]_51 chrX:55054624-55054704 0.00015 8_[+1]_64 chr6:159303106-159303186 0.00015 72_[+1] chr1:70005902-70005982 0.00017 41_[+1]_31 chr7:72176125-72176205 0.00017 23_[+1]_49 chr4:154449959-154450039 0.00017 16_[+1]_56 chr17:14064888-14064968 0.00017 11_[+1]_61 chrX:47535543-47535623 0.00017 43_[+1]_29 chr17:52938595-52938675 0.00018 26_[+1]_46 chr14:35122449-35122529 0.00018 59_[+1]_13 chr19:381064-381144 0.00018 70_[+1]_2 chr21:47875773-47875853 0.00021 69_[+1]_3 chr11:34258293-34258373 0.00021 3_[+1]_69 chr5:29796336-29796416 0.00021 43_[+1]_29 chr9:4862954-4863034 0.00021 52_[+1]_20 chr5:32288424-32288504 0.00021 30_[+1]_42 chr4:140364982-140365062 0.00021 12_[+1]_60 chr6:10725441-10725521 0.00024 59_[+1]_13 chr4:103277041-103277121 0.00024 33_[+1]_39 chr2:239331042-239331122 0.00024 31_[+1]_41 chr16:12387230-12387310 0.00027 10_[+1]_62 chr8:98790786-98790866 0.00027 53_[+1]_19 chr3:125152084-125152164 0.00027 11_[+1]_61 chr11:61109833-61109913 0.00027 34_[+1]_38 chr5:37576381-37576461 0.00032 22_[+1]_50 chr1:207809096-207809176 0.00032 60_[+1]_12 chr4:25052509-25052589 0.00032 31_[+1]_41 chr3:6582803-6582883 0.00038 71_[+1]_1 chr1:65487638-65487718 0.00038 50_[+1]_22 chr8:144016040-144016120 0.00038 1_[+1]_71 chr8:66655618-66655698 0.00043 43_[+1]_29 chr21:40357697-40357777 0.00043 68_[+1]_4 chr1:228366650-228366730 0.00043 21_[+1]_51 chr1:186015755-186015835 0.00046 72_[+1] chr8:103393669-103393749 0.00046 67_[+1]_5 chr19:14502092-14502172 0.00049 16_[+1]_56 chr14:24725570-24725650 0.00049 17_[+1]_55 chr7:102082194-102082274 0.00054 70_[+1]_2 chr5:153753465-153753545 0.00054 5_[+1]_67 chr4:145061885-145061965 0.00054 32_[+1]_40 chr4:144826768-144826848 0.00054 21_[+1]_51 chr4:1884777-1884857 0.00054 43_[+1]_29 chr4:144940562-144940642 0.00054 7_[+1]_65 chr18:43733358-43733438 0.0006 61_[+1]_11 chr3:143002405-143002485 0.0006 72_[+1] chr4:99722527-99722607 0.0006 5_[+1]_67 chr7:24903973-24904053 0.00065 65_[+1]_7 chr17:62971009-62971089 0.00065 61_[+1]_11 chr16:66651872-66651952 0.00075 3_[+1]_69 chr7:100909442-100909522 0.00075 29_[+1]_43 chr20:48715003-48715083 0.00075 22_[+1]_50 chr7:99320990-99321070 0.00075 28_[+1]_44 chr5:71462351-71462431 0.00075 52_[+1]_20 chr2:169990978-169991058 0.00075 59_[+1]_13 chr6:80314384-80314464 0.00075 38_[+1]_34 chr3:177148569-177148649 0.00075 31_[+1]_41 chr1:224058441-224058521 0.00075 [+1]_72 chr11:57415825-57415905 0.00081 54_[+1]_18 chr13:44961227-44961307 0.00081 65_[+1]_7 chr12:28345242-28345322 0.00081 62_[+1]_10 chr13:39573070-39573150 0.00084 8_[+1]_64 chr7:158628231-158628311 0.00084 71_[+1]_1 chr2:158755887-158755967 0.00084 72_[+1] chr3:57584942-57585022 0.00089 31_[+1]_41 chr6:27741820-27741900 0.00095 [+1]_72 chr3:129512900-129512980 0.00095 40_[+1]_32 chr10:13747877-13747957 0.00095 31_[+1]_41 chr8:38068319-38068399 0.00095 28_[+1]_44 chr4:144896854-144896934 0.001 31_[+1]_41 chr4:144775941-144776021 0.001 41_[+1]_31 chr4:145000047-145000127 0.001 40_[+1]_32 chr3:32115899-32115979 0.001 53_[+1]_19 chr7:5123118-5123198 0.0011 54_[+1]_18 chrX:153119183-153119263 0.0012 30_[+1]_42 chr17:73444681-73444761 0.0012 68_[+1]_4 chr12:125369547-12536962 0.0013 68_[+1]_4 chr1:6489893-6489973 0.0013 42_[+1]_30 chr3:138941040-138941120 0.0014 57_[+1]_15 chr11:118306980-11830706 0.0014 70_[+1]_2 chr16:56323922-56324002 0.0016 7_[+1]_65 chr6:13381105-13381185 0.0017 43_[+1]_29 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGV MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGATAAGV width=8 seqs=127 chr15:35459068-35459148 ( 47) AGATAAGA 1 chr1:35602539-35602619 ( 34) AGATAAGA 1 chr15:31270658-31270738 ( 2) AGATAAGA 1 chr7:43026534-43026614 ( 16) AGATAAGA 1 chr6:16263876-16263956 ( 14) AGATAAGA 1 chr9:102907620-102907700 ( 12) AGATAAGA 1 chr9:69491642-69491722 ( 27) AGATAAGA 1 chr14:88491087-88491167 ( 70) AGATAAGA 1 chr8:101776304-101776384 ( 6) AGATAAGG 1 chr2:74469931-74470011 ( 35) AGATAAGG 1 chr7:104607698-104607778 ( 16) AGATAAGG 1 chr13:25926488-25926568 ( 1) AGATAAGG 1 chrX:102356741-102356821 ( 17) AGATAAGG 1 chr13:44956976-44957056 ( 13) AGATAAGG 1 chr17:26854455-26854535 ( 31) AGATAAGG 1 chr9:128239615-128239695 ( 72) AGATAAGG 1 chr16:21548249-21548329 ( 37) AGATAAGG 1 chr13:19398967-19399047 ( 25) AGATAAGG 1 chrX:47572287-47572367 ( 64) AGATAAGG 1 chr14:23366712-23366792 ( 18) AGATAAGG 1 chr12:9039978-9040058 ( 50) AGATAAGC 1 chr11:876095-876175 ( 70) AGATAAGC 1 chr16:10437118-10437198 ( 42) AGATAAGC 1 chr11:62645227-62645307 ( 60) TGATAAGA 1 chr1:109677197-109677277 ( 22) TGATAAGA 1 chr11:2324971-2325051 ( 54) TGATAAGA 1 chrX:107801626-107801706 ( 27) TGATAAGA 1 chr1:25739906-25739986 ( 65) TGATAAGA 1 chr15:39432311-39432391 ( 7) TGATAAGA 1 chr1:207020985-207021065 ( 54) TGATAAGA 1 chr7:44120936-44121016 ( 17) AGATAACA 1 chr1:207693585-207693665 ( 48) AGATAAAA 1 chr22:36764684-36764764 ( 13) AGATAACA 1 chr19:6682880-6682960 ( 16) AGATAAAA 1 chr11:5617995-5618075 ( 8) AGATAAAA 1 chr7:39849955-39850035 ( 31) AGATAACA 1 chr2:58916117-58916197 ( 21) AGATAAAA 1 chr16:9171927-9172007 ( 1) AGATAAAA 1 chr1:207191103-207191183 ( 20) TGATAAGG 1 chr3:141567989-141568069 ( 69) TGATAAGG 1 chrX:55041559-55041639 ( 67) AGATAGGA 1 chr5:150845251-150845331 ( 67) AGATAGGA 1 chr16:25783249-25783329 ( 31) AGATAGGA 1 chr8:2645844-2645924 ( 51) AGATAGGA 1 chr20:42319698-42319778 ( 23) AGATAAAG 1 chr10:63540228-63540308 ( 46) AGATAAAG 1 chr17:19913648-19913728 ( 22) AGATAAAG 1 chrX:55054624-55054704 ( 9) AGATAAAG 1 chr6:159303106-159303186 ( 73) AGATAAAG 1 chr1:70005902-70005982 ( 42) AGATAGGG 1 chr7:72176125-72176205 ( 24) AGATAGGG 1 chr4:154449959-154450039 ( 17) AGATAGGG 1 chr17:14064888-14064968 ( 12) AGATAGGG 1 chrX:47535543-47535623 ( 44) AGATAGGG 1 chr17:52938595-52938675 ( 27) TGATAAGC 1 chr14:35122449-35122529 ( 60) TGATAAGC 1 chr19:381064-381144 ( 71) TGATAAGC 1 chr21:47875773-47875853 ( 70) AGATAACC 1 chr11:34258293-34258373 ( 4) AGATAAAC 1 chr5:29796336-29796416 ( 44) AGATAACC 1 chr9:4862954-4863034 ( 53) AGATAAAC 1 chr5:32288424-32288504 ( 31) AGATAAAC 1 chr4:140364982-140365062 ( 13) AGATAAAC 1 chr6:10725441-10725521 ( 60) AGATAGGC 1 chr4:103277041-103277121 ( 34) AGATTAGA 1 chr2:239331042-239331122 ( 32) AGATAGGC 1 chr16:12387230-12387310 ( 11) TGATAACA 1 chr8:98790786-98790866 ( 54) TGATAACA 1 chr3:125152084-125152164 ( 12) TGATAACA 1 chr11:61109833-61109913 ( 35) TGATAAAA 1 chr5:37576381-37576461 ( 23) AGATTAGG 1 chr1:207809096-207809176 ( 61) AGATTAGG 1 chr4:25052509-25052589 ( 32) AGATAAGT 1 chr3:6582803-6582883 ( 72) AGATAGAA 1 chr1:65487638-65487718 ( 51) TGATAAAG 1 chr8:144016040-144016120 ( 2) TGATAACG 1 chr8:66655618-66655698 ( 44) AGATAGCG 1 chr21:40357697-40357777 ( 69) AGATAGAG 1 chr1:228366650-228366730 ( 22) AGATAGAG 1 chr1:186015755-186015835 ( 73) AGATGAGA 1 chr8:103393669-103393749 ( 68) AGATGAGA 1 chr19:14502092-14502172 ( 17) TGATAACC 1 chr14:24725570-24725650 ( 18) TGATAACC 1 chr7:102082194-102082274 ( 71) TGATTAGA 1 chr5:153753465-153753545 ( 6) TGATTAGA 1 chr4:145061885-145061965 ( 33) TGATAGGC 1 chr4:144826768-144826848 ( 22) TGATAGGC 1 chr4:1884777-1884857 ( 44) AGATGAGG 1 chr4:144940562-144940642 ( 8) TGATAGGC 1 chr18:43733358-43733438 ( 62) AGATAGCC 1 chr3:143002405-143002485 ( 73) AGATTAAA 1 chr4:99722527-99722607 ( 6) AGATTACA 1 chr7:24903973-24904053 ( 66) TGATAAGT 1 chr17:62971009-62971089 ( 62) TGATTAGG 1 chr16:66651872-66651952 ( 4) TGATAGCA 1 chr7:100909442-100909522 ( 30) AGATTACG 1 chr20:48715003-48715083 ( 23) TGATAGCA 1 chr7:99320990-99321070 ( 29) AGATAACT 1 chr5:71462351-71462431 ( 53) AGATAACT 1 chr2:169990978-169991058 ( 60) TGATAGCA 1 chr6:80314384-80314464 ( 39) AGATAACT 1 chr3:177148569-177148649 ( 32) AGATTAAG 1 chr1:224058441-224058521 ( 1) AGATTAAG 1 chr11:57415825-57415905 ( 55) GGATAAGA 1 chr13:44961227-44961307 ( 66) AGATAGGT 1 chr12:28345242-28345322 ( 63) GGATAAGA 1 chr13:39573070-39573150 ( 9) TGATAGAG 1 chr7:158628231-158628311 ( 72) TGATAGAG 1 chr2:158755887-158755967 ( 73) TGATAGAG 1 chr3:57584942-57585022 ( 32) TGATTAGC 1 chr6:27741820-27741900 ( 1) AGATTAAC 1 chr3:129512900-129512980 ( 41) AGATGACA 1 chr10:13747877-13747957 ( 32) AGATTACC 1 chr8:38068319-38068399 ( 29) AGATGAAA 1 chr4:144896854-144896934 ( 32) AGATGGGA 1 chr4:144775941-144776021 ( 42) AGATGGGA 1 chr4:145000047-145000127 ( 41) AGATGGGA 1 chr3:32115899-32115979 ( 54) AGATGGGA 1 chr7:5123118-5123198 ( 55) TGATTACA 1 chrX:153119183-153119263 ( 31) GGATAAGC 1 chr17:73444681-73444761 ( 69) AGATTAGT 1 chr12:125369547-12536962 ( 69) TGATAACT 1 chr1:6489893-6489973 ( 43) TGATGAGC 1 chr3:138941040-138941120 ( 58) AGATTGAG 1 chr11:118306980-11830706 ( 71) AGATTGCG 1 chr16:56323922-56324002 ( 8) GGATAAAG 1 chr6:13381105-13381185 ( 44) AGATTGCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGV MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.89709 E= 2.2e-046 145 -1363 -299 16 -1363 -1363 200 -1363 202 -1363 -1363 -1363 -1363 -1363 -1363 194 164 -1363 -167 -80 158 -1363 5 -1363 -11 -18 116 -1363 70 -24 40 -205 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGV MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 127 E= 2.2e-046 0.677165 0.000000 0.031496 0.291339 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.771654 0.000000 0.078740 0.149606 0.740157 0.000000 0.259843 0.000000 0.228346 0.212598 0.559055 0.000000 0.401575 0.204724 0.330709 0.062992 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGV MEME-1 regular expression -------------------------------------------------------------------------------- [AT]GATA[AG][GAC][AGC] -------------------------------------------------------------------------------- Time 5.02 secs. ******************************************************************************** ******************************************************************************** MOTIF BYTTATCT MEME-2 width = 8 sites = 96 llr = 695 E-value = 6.7e-032 ******************************************************************************** -------------------------------------------------------------------------------- Motif BYTTATCT MEME-2 Description -------------------------------------------------------------------------------- Simplified A :1::9::2 pos.-specific C 452:::a: probability G 32:::::: matrix T 338a1a:8 bits 2.0 * 1.8 ** 1.6 **** 1.4 **** Relative 1.2 ****** Entropy 1.0 ****** (10.4 bits) 0.8 ****** 0.6 ****** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCTTATCT consensus GTC sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BYTTATCT MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:171164795-171164875 10 1.62e-05 acagttaaa ccttatct ctactaaaaa chr16:66651872-66651952 45 1.62e-05 CTGCTTCCTC CCTTATCT CCCAGACCTG chr17:26295374-26295454 4 1.62e-05 ATT CCTTATCT TCAGGCACTC chr16:56323922-56324002 20 1.62e-05 ataaagccag ccttatct cctgtagctc chr16:23678669-23678749 20 1.62e-05 TGTGCTTACA CCTTATCT ATGAACAGTC chr14:103844525-10384460 8 1.62e-05 ACTAACG CCTTATCT GGTGTTGCAG chr13:50420835-50420915 72 1.62e-05 AGCCCATGTT CCTTATCT C chr5:42873109-42873189 19 3.31e-05 ACTGTGGCTC GCTTATCT CATGCTTGCA chr15:69284230-69284310 55 3.31e-05 ccttgcatgg gcttatct cataatgttc chr2:173465564-173465644 18 3.31e-05 tcttcgtcca gcttatct ggaagggaga chr3:128773654-128773734 73 3.31e-05 tttcagtatt gcttatct chr9:131355491-131355571 18 3.31e-05 GTCGATGACT GCTTATCT CATTGGTTGC chr1:151687984-151688064 42 3.31e-05 CTACCCAGCT GCTTATCT CCCAAACCAG chr14:20645709-20645789 39 3.31e-05 tgcaactcat gcttatct atcttgtgac chr5:134528296-134528376 72 3.31e-05 TTGTCTCCTG GCTTATCT G chr6:142337967-142338047 41 5.06e-05 caccccaacc tcttatct ctgcacccca chr9:101338780-101338860 23 5.06e-05 CTTACTACAG TCTTATCT TAAgggccag chr4:154449959-154450039 62 5.06e-05 TGCAATGGTT TCTTATCT GACCATGCAC chr2:30736590-30736670 68 5.06e-05 accatttgtc tcttatct accta chr1:211395919-211395999 43 5.06e-05 gatgccttcc tcttatct caactgcaaa chr1:35309349-35309429 41 6.81e-05 GGGAGGCCTC CTTTATCT CTGGCTCCAG chr2:127752074-127752154 49 6.81e-05 cacaggggaa ctttatct cctgctcttc chr2:32705198-32705278 39 6.81e-05 ttgatattct ctttatct ggagtagatt chr17:73444681-73444761 6 6.81e-05 TCTAG CTTTATCT TCTGTTGCAC chr6:10725441-10725521 50 6.81e-05 GTTTTTGCCT CTTTATCT ACAGATAGGC chr1:63156058-63156138 64 6.81e-05 TGTTGCATGC CTTTATCT CTGTTCTCC chr3:32115899-32115979 17 6.81e-05 ttcctttact ctttatct ccagaaccca chr11:124537653-12453773 50 6.81e-05 GCTTCTATAT CTTTATCT CTTCTAGACA chr6:10750103-10750183 49 6.81e-05 ATTTTTGCCT CTTTATCT AAAGGTAGGC chr1:27118210-27118290 36 1.03e-04 GGCTAGGGCT GTTTATCT GTGACTGTCA chr7:77502865-77502945 61 1.03e-04 gcagcacaag gtttatct cttcagacaa chr3:57584942-57585022 67 1.03e-04 tcagatatgc gtttatct cagtga chr11:16626424-16626504 13 1.22e-04 CACCAATTCT TTTTATCT TAAAGCTCTG chr3:6582803-6582883 15 1.22e-04 gaggtggggg ttttatct ataagtccct chr1:224058441-224058521 72 1.22e-04 gagatgagca ttttatct g chr15:40851727-40851807 68 1.55e-04 TCACATTACT CCCTATCT TTCTA chr19:51727514-51727594 33 1.55e-04 cttttagctt ccctatct tagtgcacct chr5:175624414-175624494 59 1.55e-04 gctttagctt ccctatct tagtgcatct chr1:228608967-228609047 54 1.55e-04 tgctccttga ggttatct actgggacat chr4:68418029-68418109 53 1.55e-04 cttttagctt ccctatct tagtgcacct chr7:5123118-5123198 16 1.55e-04 CATCCGGCAT GGTTATCT GCGCTTGCAA chrX:79767986-79768066 10 1.55e-04 ttttagctt ccctatct tagtgtgcct chr20:33780333-33780413 32 1.55e-04 cttttagctt ccctatct tagtgcacct chr3:14162506-14162586 73 1.55e-04 cttttagctt ccctatct chr12:27170378-27170458 26 1.55e-04 cttttagctt ccctatct tagtgcacct chr10:28783474-28783554 19 1.73e-04 ggataacctc tgttatct tcagggccca chr19:38613546-38613626 59 1.73e-04 atgcactgtg tgttatct gttcactgcc chr6:27741820-27741900 29 1.73e-04 acactggtta tgttatct atagtttcca chr22:36764684-36764764 40 1.73e-04 GGTGGAGGAG TGTTATCT CCCCACCCTT chr7:140091606-140091686 20 1.73e-04 gcaaccttat tgttatct gtactgcaca chr11:71706834-71706914 18 1.73e-04 CCTCAGGCTG TGTTATCT TACACTGGCA chr15:74902916-74902996 48 1.73e-04 TGCTTTTGGC TGTTATCT ATCACGACAG chr11:3900072-3900152 8 2.04e-04 CTCGGCT GCCTATCT TCCCCCGACA chr3:98302759-98302839 72 2.04e-04 CCACAGTTCT GCCTATCT C chr17:31298382-31298462 35 2.04e-04 ctgggaaggt ccttatca agtgctcctg chr6:160992404-160992484 11 2.04e-04 gcagtctgtc ccttatca gagctctagt chr2:58916117-58916197 30 2.20e-04 tagataaaac tcctatct ccctgggaca chr20:30505819-30505899 15 2.20e-04 cttttagctt tcctatct tagtgcacct chr10:19024850-19024930 46 2.36e-04 CTTATTGTGG GCTTATCA ACAGCAGGAG chr14:100038918-10003899 52 2.36e-04 GACGACAGCT GCTTATCA TCCAAGCCCC chr6:159303106-159303186 8 2.36e-04 gtaatgg gcttatca gtaatgtgaa chr8:38068319-38068399 11 2.36e-04 CACACAACAG GCTTATCA GAAACCTACC chr1:25606345-25606425 35 2.36e-04 GAGCCCATCA GCTTATCA AACCAGCAGC chr4:84417384-84417464 39 2.69e-04 cttttagctt ctctatct tagtattcct chr3:101249330-101249410 38 3.18e-04 cacccccctc ctttatca tgcagttggg chr1:65696954-65697034 22 3.52e-04 GAATAAATGC CATTATCT GTATGTTTCA chr13:44972142-44972222 32 3.52e-04 TCCGATTAGT CATTATCT CCTCTGTGGT chr3:129512900-129512980 3 3.52e-04 AA TTCTATCT CAGGAGCAAA chr11:2000372-2000452 20 4.01e-04 GAGAAGTCCC CGTTATCA GCAGCGAGCC chr1:191793077-191793157 22 4.01e-04 ATTTCAAAAA GTTTATCA TTTTGAGAAG chr9:100987560-100987640 15 4.53e-04 AGCCATCTGG TGCTATCT CCTAGAGCCC chr18:77361330-77361410 28 4.53e-04 ctctgaagtc tgctatct gagagcttcc chr13:39573070-39573150 55 4.53e-04 catgtgctat ttttatca ccctttgtgg chr5:153753465-153753545 69 4.53e-04 TGGTACAGGA GATTATCT CATT chr10:7049687-7049767 12 4.53e-04 TTCCTTCCCA TGCTATCT CCTTAGGCCA chr14:23366712-23366792 57 4.53e-04 CACATGCCCA TGCTATCT CCCAGGGCCC chr1:95100702-95100782 23 5.02e-04 GGGAGCAGCT GGTTATCA TGAACCATGT chr1:28851661-28851741 4 5.02e-04 act ggttatca gaacggaaca chr10:13747877-13747957 71 5.02e-04 ATTCCTACCG GGTTATCA TG chr4:69730317-69730397 36 5.51e-04 tgagcacatt ccttttct ttctggacac chr12:53703911-53703991 18 5.51e-04 AAGGTTCCAA CCTTTTCT CTCCAGTTAT chr20:9129847-9129927 13 5.51e-04 accagactcc ccttttct ccacagcagc chr9:125209218-125209298 26 6.01e-04 caaggaaatc acttatct tctaacaata chr15:88214703-88214783 42 6.34e-04 TTCCAGATTC TCTTTTCT CTATCCTGAA chrX:55041559-55041639 17 6.65e-04 CCAGGCCTCT GCTCATCT GTCCATGACA chrX:153119183-153119263 54 6.65e-04 taaatgctga gctcatct ctcagctcat chr14:35122449-35122529 69 6.65e-04 ctgataagcc ctctatca ttac chr2:209436645-209436725 70 6.97e-04 attttgtcac tctcatct cct chr1:243269310-243269390 45 6.97e-04 cccatcctaa tctcatct tgaattccca chr16:25783249-25783329 66 7.46e-04 cgttggcaaa ctttttct gtaaagg chr10:72318683-72318763 34 7.94e-04 agttgcattt ttctatca gccgagggtc chr2:240008152-240008232 69 7.94e-04 ATGTGGATCT GACTATCT CTCA chr12:9039978-9040058 15 8.81e-04 gtaagctcct gtttttct tgctgtgcag chr7:104607698-104607778 46 9.50e-04 TGGTTCAGTT GATTATCA GTATCTTCAG chr15:35459068-35459148 7 9.50e-04 AGAAAA TGCTATCA TTCTCAAGCA chr15:75987015-75987095 19 1.02e-03 AATCCCCTCT AGTTATCT CCTCCTGCCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BYTTATCT MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:171164795-171164875 1.6e-05 9_[+2]_63 chr16:66651872-66651952 1.6e-05 44_[+2]_28 chr17:26295374-26295454 1.6e-05 3_[+2]_69 chr16:56323922-56324002 1.6e-05 19_[+2]_53 chr16:23678669-23678749 1.6e-05 19_[+2]_53 chr14:103844525-10384460 1.6e-05 7_[+2]_65 chr13:50420835-50420915 1.6e-05 71_[+2]_1 chr5:42873109-42873189 3.3e-05 18_[+2]_54 chr15:69284230-69284310 3.3e-05 54_[+2]_18 chr2:173465564-173465644 3.3e-05 17_[+2]_55 chr3:128773654-128773734 3.3e-05 72_[+2] chr9:131355491-131355571 3.3e-05 17_[+2]_55 chr1:151687984-151688064 3.3e-05 41_[+2]_31 chr14:20645709-20645789 3.3e-05 38_[+2]_34 chr5:134528296-134528376 3.3e-05 71_[+2]_1 chr6:142337967-142338047 5.1e-05 40_[+2]_32 chr9:101338780-101338860 5.1e-05 22_[+2]_50 chr4:154449959-154450039 5.1e-05 61_[+2]_11 chr2:30736590-30736670 5.1e-05 67_[+2]_5 chr1:211395919-211395999 5.1e-05 42_[+2]_30 chr1:35309349-35309429 6.8e-05 40_[+2]_32 chr2:127752074-127752154 6.8e-05 48_[+2]_24 chr2:32705198-32705278 6.8e-05 38_[+2]_34 chr17:73444681-73444761 6.8e-05 5_[+2]_67 chr6:10725441-10725521 6.8e-05 49_[+2]_23 chr1:63156058-63156138 6.8e-05 63_[+2]_9 chr3:32115899-32115979 6.8e-05 16_[+2]_56 chr11:124537653-12453773 6.8e-05 49_[+2]_23 chr6:10750103-10750183 6.8e-05 48_[+2]_24 chr1:27118210-27118290 0.0001 35_[+2]_37 chr7:77502865-77502945 0.0001 60_[+2]_12 chr3:57584942-57585022 0.0001 66_[+2]_6 chr11:16626424-16626504 0.00012 12_[+2]_60 chr3:6582803-6582883 0.00012 14_[+2]_58 chr1:224058441-224058521 0.00012 71_[+2]_1 chr15:40851727-40851807 0.00015 67_[+2]_5 chr19:51727514-51727594 0.00015 32_[+2]_40 chr5:175624414-175624494 0.00015 58_[+2]_14 chr1:228608967-228609047 0.00015 53_[+2]_19 chr4:68418029-68418109 0.00015 52_[+2]_20 chr7:5123118-5123198 0.00015 15_[+2]_57 chrX:79767986-79768066 0.00015 9_[+2]_63 chr20:33780333-33780413 0.00015 31_[+2]_41 chr3:14162506-14162586 0.00015 72_[+2] chr12:27170378-27170458 0.00015 25_[+2]_47 chr10:28783474-28783554 0.00017 18_[+2]_54 chr19:38613546-38613626 0.00017 58_[+2]_14 chr6:27741820-27741900 0.00017 28_[+2]_44 chr22:36764684-36764764 0.00017 39_[+2]_33 chr7:140091606-140091686 0.00017 19_[+2]_53 chr11:71706834-71706914 0.00017 17_[+2]_55 chr15:74902916-74902996 0.00017 47_[+2]_25 chr11:3900072-3900152 0.0002 7_[+2]_65 chr3:98302759-98302839 0.0002 71_[+2]_1 chr17:31298382-31298462 0.0002 34_[+2]_38 chr6:160992404-160992484 0.0002 10_[+2]_62 chr2:58916117-58916197 0.00022 29_[+2]_43 chr20:30505819-30505899 0.00022 14_[+2]_58 chr10:19024850-19024930 0.00024 45_[+2]_27 chr14:100038918-10003899 0.00024 51_[+2]_21 chr6:159303106-159303186 0.00024 7_[+2]_65 chr8:38068319-38068399 0.00024 10_[+2]_62 chr1:25606345-25606425 0.00024 34_[+2]_38 chr4:84417384-84417464 0.00027 38_[+2]_34 chr3:101249330-101249410 0.00032 37_[+2]_35 chr1:65696954-65697034 0.00035 21_[+2]_51 chr13:44972142-44972222 0.00035 31_[+2]_41 chr3:129512900-129512980 0.00035 2_[+2]_70 chr11:2000372-2000452 0.0004 19_[+2]_53 chr1:191793077-191793157 0.0004 21_[+2]_51 chr9:100987560-100987640 0.00045 14_[+2]_58 chr18:77361330-77361410 0.00045 27_[+2]_45 chr13:39573070-39573150 0.00045 54_[+2]_18 chr5:153753465-153753545 0.00045 68_[+2]_4 chr10:7049687-7049767 0.00045 11_[+2]_61 chr14:23366712-23366792 0.00045 56_[+2]_16 chr1:95100702-95100782 0.0005 22_[+2]_50 chr1:28851661-28851741 0.0005 3_[+2]_69 chr10:13747877-13747957 0.0005 70_[+2]_2 chr4:69730317-69730397 0.00055 35_[+2]_37 chr12:53703911-53703991 0.00055 17_[+2]_55 chr20:9129847-9129927 0.00055 12_[+2]_60 chr9:125209218-125209298 0.0006 25_[+2]_47 chr15:88214703-88214783 0.00063 41_[+2]_31 chrX:55041559-55041639 0.00067 16_[+2]_56 chrX:153119183-153119263 0.00067 53_[+2]_19 chr14:35122449-35122529 0.00067 68_[+2]_4 chr2:209436645-209436725 0.0007 69_[+2]_3 chr1:243269310-243269390 0.0007 44_[+2]_28 chr16:25783249-25783329 0.00075 65_[+2]_7 chr10:72318683-72318763 0.00079 33_[+2]_39 chr2:240008152-240008232 0.00079 68_[+2]_4 chr12:9039978-9040058 0.00088 14_[+2]_58 chr7:104607698-104607778 0.00095 45_[+2]_27 chr15:35459068-35459148 0.00095 6_[+2]_66 chr15:75987015-75987095 0.001 18_[+2]_54 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BYTTATCT MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF BYTTATCT width=8 seqs=96 chr3:171164795-171164875 ( 10) CCTTATCT 1 chr16:66651872-66651952 ( 45) CCTTATCT 1 chr17:26295374-26295454 ( 4) CCTTATCT 1 chr16:56323922-56324002 ( 20) CCTTATCT 1 chr16:23678669-23678749 ( 20) CCTTATCT 1 chr14:103844525-10384460 ( 8) CCTTATCT 1 chr13:50420835-50420915 ( 72) CCTTATCT 1 chr5:42873109-42873189 ( 19) GCTTATCT 1 chr15:69284230-69284310 ( 55) GCTTATCT 1 chr2:173465564-173465644 ( 18) GCTTATCT 1 chr3:128773654-128773734 ( 73) GCTTATCT 1 chr9:131355491-131355571 ( 18) GCTTATCT 1 chr1:151687984-151688064 ( 42) GCTTATCT 1 chr14:20645709-20645789 ( 39) GCTTATCT 1 chr5:134528296-134528376 ( 72) GCTTATCT 1 chr6:142337967-142338047 ( 41) TCTTATCT 1 chr9:101338780-101338860 ( 23) TCTTATCT 1 chr4:154449959-154450039 ( 62) TCTTATCT 1 chr2:30736590-30736670 ( 68) TCTTATCT 1 chr1:211395919-211395999 ( 43) TCTTATCT 1 chr1:35309349-35309429 ( 41) CTTTATCT 1 chr2:127752074-127752154 ( 49) CTTTATCT 1 chr2:32705198-32705278 ( 39) CTTTATCT 1 chr17:73444681-73444761 ( 6) CTTTATCT 1 chr6:10725441-10725521 ( 50) CTTTATCT 1 chr1:63156058-63156138 ( 64) CTTTATCT 1 chr3:32115899-32115979 ( 17) CTTTATCT 1 chr11:124537653-12453773 ( 50) CTTTATCT 1 chr6:10750103-10750183 ( 49) CTTTATCT 1 chr1:27118210-27118290 ( 36) GTTTATCT 1 chr7:77502865-77502945 ( 61) GTTTATCT 1 chr3:57584942-57585022 ( 67) GTTTATCT 1 chr11:16626424-16626504 ( 13) TTTTATCT 1 chr3:6582803-6582883 ( 15) TTTTATCT 1 chr1:224058441-224058521 ( 72) TTTTATCT 1 chr15:40851727-40851807 ( 68) CCCTATCT 1 chr19:51727514-51727594 ( 33) CCCTATCT 1 chr5:175624414-175624494 ( 59) CCCTATCT 1 chr1:228608967-228609047 ( 54) GGTTATCT 1 chr4:68418029-68418109 ( 53) CCCTATCT 1 chr7:5123118-5123198 ( 16) GGTTATCT 1 chrX:79767986-79768066 ( 10) CCCTATCT 1 chr20:33780333-33780413 ( 32) CCCTATCT 1 chr3:14162506-14162586 ( 73) CCCTATCT 1 chr12:27170378-27170458 ( 26) CCCTATCT 1 chr10:28783474-28783554 ( 19) TGTTATCT 1 chr19:38613546-38613626 ( 59) TGTTATCT 1 chr6:27741820-27741900 ( 29) TGTTATCT 1 chr22:36764684-36764764 ( 40) TGTTATCT 1 chr7:140091606-140091686 ( 20) TGTTATCT 1 chr11:71706834-71706914 ( 18) TGTTATCT 1 chr15:74902916-74902996 ( 48) TGTTATCT 1 chr11:3900072-3900152 ( 8) GCCTATCT 1 chr3:98302759-98302839 ( 72) GCCTATCT 1 chr17:31298382-31298462 ( 35) CCTTATCA 1 chr6:160992404-160992484 ( 11) CCTTATCA 1 chr2:58916117-58916197 ( 30) TCCTATCT 1 chr20:30505819-30505899 ( 15) TCCTATCT 1 chr10:19024850-19024930 ( 46) GCTTATCA 1 chr14:100038918-10003899 ( 52) GCTTATCA 1 chr6:159303106-159303186 ( 8) GCTTATCA 1 chr8:38068319-38068399 ( 11) GCTTATCA 1 chr1:25606345-25606425 ( 35) GCTTATCA 1 chr4:84417384-84417464 ( 39) CTCTATCT 1 chr3:101249330-101249410 ( 38) CTTTATCA 1 chr1:65696954-65697034 ( 22) CATTATCT 1 chr13:44972142-44972222 ( 32) CATTATCT 1 chr3:129512900-129512980 ( 3) TTCTATCT 1 chr11:2000372-2000452 ( 20) CGTTATCA 1 chr1:191793077-191793157 ( 22) GTTTATCA 1 chr9:100987560-100987640 ( 15) TGCTATCT 1 chr18:77361330-77361410 ( 28) TGCTATCT 1 chr13:39573070-39573150 ( 55) TTTTATCA 1 chr5:153753465-153753545 ( 69) GATTATCT 1 chr10:7049687-7049767 ( 12) TGCTATCT 1 chr14:23366712-23366792 ( 57) TGCTATCT 1 chr1:95100702-95100782 ( 23) GGTTATCA 1 chr1:28851661-28851741 ( 4) GGTTATCA 1 chr10:13747877-13747957 ( 71) GGTTATCA 1 chr4:69730317-69730397 ( 36) CCTTTTCT 1 chr12:53703911-53703991 ( 18) CCTTTTCT 1 chr20:9129847-9129927 ( 13) CCTTTTCT 1 chr9:125209218-125209298 ( 26) ACTTATCT 1 chr15:88214703-88214783 ( 42) TCTTTTCT 1 chrX:55041559-55041639 ( 17) GCTCATCT 1 chrX:153119183-153119263 ( 54) GCTCATCT 1 chr14:35122449-35122529 ( 69) CTCTATCA 1 chr2:209436645-209436725 ( 70) TCTCATCT 1 chr1:243269310-243269390 ( 45) TCTCATCT 1 chr16:25783249-25783329 ( 66) CTTTTTCT 1 chr10:72318683-72318763 ( 34) TTCTATCA 1 chr2:240008152-240008232 ( 69) GACTATCT 1 chr12:9039978-9040058 ( 15) GTTTTTCT 1 chr7:104607698-104607778 ( 46) GATTATCA 1 chr15:35459068-35459148 ( 7) TGCTATCA 1 chr15:75987015-75987095 ( 19) AGTTATCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BYTTATCT MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.01253 E= 6.7e-032 -357 63 32 16 -225 105 -34 -6 -1323 -8 -1323 156 -1323 -253 -1323 188 192 -1323 -1323 -206 -1323 -1323 -1323 194 -1323 205 -1323 -1323 -40 -1323 -1323 164 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BYTTATCT MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 96 E= 6.7e-032 0.020833 0.375000 0.312500 0.291667 0.052083 0.500000 0.197917 0.250000 0.000000 0.229167 0.000000 0.770833 0.000000 0.041667 0.000000 0.958333 0.937500 0.000000 0.000000 0.062500 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.187500 0.000000 0.000000 0.812500 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BYTTATCT MEME-2 regular expression -------------------------------------------------------------------------------- [CGT][CT][TC]TATCT -------------------------------------------------------------------------------- Time 8.64 secs. ******************************************************************************** ******************************************************************************** MOTIF SCAGCTGB MEME-3 width = 8 sites = 111 llr = 729 E-value = 1.5e-014 ******************************************************************************** -------------------------------------------------------------------------------- Motif SCAGCTGB MEME-3 Description -------------------------------------------------------------------------------- Simplified A 2:7:33:: pos.-specific C 5a::7::4 probability G 3::8::a3 matrix T ::32:7:3 bits 2.0 * * 1.8 * * 1.6 * * 1.4 * * Relative 1.2 * * * Entropy 1.0 ****** (9.5 bits) 0.8 ****** 0.6 ****** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCAGCTGC consensus G T AA G sequence A T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SCAGCTGB MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:35309349-35309429 55 2.84e-05 ATCTCTGGCT CCAGCTGG ACTCAGGAAA chr17:14064888-14064968 51 2.84e-05 tgggtaacat ccagctgg ctggaggctg chr22:36764684-36764764 65 4.34e-05 CTTACCCCTC CCAGCTGT CTATATCG chr15:74902916-74902996 69 4.34e-05 ACGACAGGCT CCAGCTGT GCAT chr12:9039978-9040058 29 5.78e-05 ttcttgctgt gcagctgc aaagtcacaa chrX:102356741-102356821 66 5.78e-05 gggtatgcct gcagctgc agaaaga chr4:84417384-84417464 1 5.78e-05 . gcagctgc aggcatatcc chr2:173465564-173465644 63 5.78e-05 catacatctt gcagctgc aggcatcccc chr5:657864-657944 41 5.78e-05 AGTGACCTGG GCAGCTGC ATCACAGGAT chr2:239331042-239331122 51 5.78e-05 AGCTCCTCCG GCAGCTGC AGTCAGGTGA chr4:140364982-140365062 60 5.78e-05 ctcccctgag gcagctgc caggcaagat chr8:37939615-37939695 9 5.78e-05 gtaacttt gcagctgc gctagggagg chr8:37949364-37949444 10 5.78e-05 tgtaacttt gcagctgc gctagggagg chr14:20645709-20645789 60 5.78e-05 ttgtgacctt gcagctgc acagcaagaa chr3:14162506-14162586 34 5.78e-05 acatctttct gcagctgc aggcatatcc chr15:69276649-69276729 65 1.03e-04 cctccccagc acagctgc aaggtcat chr15:88214703-88214783 61 1.03e-04 TATCCTGAAC ACAGCTGC TGCATTTATC chr13:95923463-95923543 41 1.03e-04 GAATACAGAG ACAGCTGC CGACGGATTA chr9:131355491-131355571 44 1.03e-04 GCTTCCATGT GCAGCTGT GTGTTCAGAG chr10:43140678-43140758 49 1.03e-04 cctccctagc acagctgc aaagttacaa chr7:77502865-77502945 14 1.03e-04 atcttgcctc acagctgc ctcaggggag chr5:16418757-16418837 44 1.30e-04 CACTCAGAAG CCAGATGC CATTTAATGT chr16:21272958-21273038 10 1.30e-04 ACATGCATG CCAGCAGC TCCCTTCTTG chr1:25606345-25606425 45 1.30e-04 GCTTATCAAA CCAGCAGC TGATGTGAGT chr1:109677197-109677277 58 1.60e-04 GGCTGCTGCA CCTGCTGC TTTTGCCGTT chr1:207809096-207809176 21 1.60e-04 gacagaggtc cctgctgc cttctgcagt chr14:36733971-36734051 41 1.60e-04 aatctttcat cctgctgc ctgcgataca chr12:125369547-12536962 15 2.03e-04 ttagtgaaac ccagatgg ctggccccgc chr15:69284230-69284310 11 2.03e-04 gctgtgcggt ccagatgg ctgttatcta chrX:47543021-47543101 58 2.03e-04 gaggtggtca ccagcagg tgattgtata chr17:31298382-31298462 62 2.03e-04 gagcactgag acagctgt gcaaacagct chr2:58916117-58916197 66 2.03e-04 ggggggaggg acagctgt gggcgca chr6:80314384-80314464 69 2.03e-04 tcactggttt ccagatgg agag chr15:39432311-39432391 17 2.03e-04 TGATAAGAGC ACAGCTGT GGGAAAGCCA chr2:158755887-158755967 11 2.03e-04 TGACCTTAGA CCAGATGG TCCCTGTGGC chr1:6489893-6489973 28 2.03e-04 GACTCAGTGG CCAGATGG CCTGGACTGA chr10:63540228-63540308 12 2.48e-04 CACTAAACAT CCAGATGT GGTCTCAGTG chr1:63156058-63156138 49 2.48e-04 ATACTCCCAG CCAGATGT TGCATGCCTT chr7:139935090-139935170 42 2.48e-04 CAGTTGACAA CCAGCAGT CTCTGCTAGA chr17:62971009-62971089 31 2.48e-04 AAATATAAAA CCAGATGT ACCTTCCAGT chr8:144016040-144016120 35 2.48e-04 GAGGCTCAAG CCAGATGT GCTGCACCGT chr5:42873109-42873189 34 2.92e-04 TCTCATGCTT GCAGCAGC CTAGAGAGAG chr16:12387230-12387310 41 2.92e-04 ATCCTGCTTT CCTGCTGT TCAGACAGTG chr11:2000372-2000452 40 2.92e-04 AGCGAGCCTG CCTGCTGT TCCTAGTCCT chr9:69491642-69491722 50 2.92e-04 gcatctgtct cctgctgt ccctgggcaa chr3:6582803-6582883 40 3.08e-04 cctgacaggg gctgctgc ctttttttca chr15:35459068-35459148 22 3.37e-04 TCATTCTCAA GCAGCAGG GAAAAGGAGC chr8:23366398-23366478 24 3.37e-04 TGGCCTGAGA GCAGATGG TTTCCGATAT chr5:29796336-29796416 68 3.37e-04 ACCAGACACT GCAGATGG TGACT chr10:75004827-75004907 3 4.26e-04 TA GCAGATGT AGCCTATGAA chr19:38613546-38613626 40 4.26e-04 tgcttaacca ccatctgc catgcactgt chr13:44972142-44972222 72 4.26e-04 TTAGCACAGA GCAGATGT C chr12:108879357-10887943 45 4.26e-04 gataagacag ccatctgc aaaaccaagg chr9:4862954-4863034 16 4.26e-04 TGAGTTAACG GCAGCAGT TGTTCAATGG chr1:25739906-25739986 22 4.26e-04 ACTCACATCA GCTGCTGG TTTGATAAGC chr20:9129847-9129927 23 4.26e-04 ccttttctcc acagcagc ctgatctcca chr1:211395919-211395999 30 4.26e-04 cgatcaggag acagatgc cttcctctta chr1:224058441-224058521 27 4.26e-04 agctatgccc acagcagc ccctcccccc chr19:381064-381144 1 4.26e-04 . GCAGATGT AGGAGGTGGA chr1:16380765-16380845 32 4.71e-04 CTCACTCAAG GCTGCTGT CAGCCCATGT chr8:2645844-2645924 12 4.71e-04 cttaaccctc actgctgc aggattgctg chr8:101776304-101776384 66 5.44e-04 TCTCCTGAAG CCATCTGG GGGATCA chr9:100987560-100987640 7 5.44e-04 AATCAG CCATCTGG TGCTATCTCC chr7:102082194-102082274 24 5.44e-04 AGCAAGTGAA CCATCTGG CGTGGAGCTG chr6:13381105-13381185 62 5.44e-04 CAGGCTTCCT CCTGCAGC CCAGAAGCCA chr18:43733358-43733438 50 5.44e-04 TCAGCTGCAG CCTGATGC AGGGAGATAG chr10:19024850-19024930 54 5.44e-04 GGGCTTATCA ACAGCAGG AGCTGGTGCA chr17:26854455-26854535 39 5.44e-04 GCAGATAAGG ACAGCAGG GCCCTGAACC chr16:10437118-10437198 14 5.44e-04 tagattgcag ccatctgg gcaccacagt chr13:19398967-19399047 61 5.44e-04 cctggacatg cctgcagc agatcagagg chr10:43142681-43142761 27 5.44e-04 ctcttatcga cctgatgc agtccatctt chr5:139990841-139990921 16 5.44e-04 catacatctt cctgcagc tacaggcata chr19:516716-516796 27 5.44e-04 gttttgtgac cctgcagc cgtgctaggg chr14:35122449-35122529 30 5.44e-04 acattaccaa acagatgg gagcattctg chr7:127478999-127479079 22 6.19e-04 gtatcttcct acagcagt gagatacgca chr15:75987015-75987095 39 6.19e-04 TCCTGCCAGC ACTGCTGG CAATACCAGC chr14:24725570-24725650 72 6.19e-04 TGGATGTCCA CCATCTGT G chr6:159303106-159303186 38 6.19e-04 tggaatgctc ccatctgt ttggttatgt chr1:228608967-228609047 7 6.19e-04 ctgcca ccagaagg tacgctgagg chr1:27118210-27118290 20 6.95e-04 AACGTGTCCA CCTGCAGG CTAGGGCTGT chr19:6682880-6682960 53 6.95e-04 agtgataatg ccagaagt gaacttcaaa chr16:21548249-21548329 55 6.95e-04 CCATGAGGCC ACTGCTGT CACACTTGGA chr3:141567989-141568069 61 7.40e-04 GGCAGCTTAG GCAGAAGC TGATAaggag chr17:62919226-62919306 59 7.86e-04 TCCTCCTTCT GCATCTGG AGTCTAGAAG chr4:154449959-154450039 47 8.31e-04 CTCAAGAGAA ACATCTGC AATGGTTTCT chr6:34249867-34249947 13 9.20e-04 TATCTGTTAT GCTGCAGG AACTGAGTAA chr17:19913648-19913728 10 9.20e-04 ACTGTAGGA GCTGCAGG CAGCAGATAA chr5:32288424-32288504 6 9.20e-04 tactg ccatcagc ctttccacct chr4:68418029-68418109 17 9.20e-04 atctttctgc gctgcagg catactcccc chr11:62645227-62645307 17 1.01e-03 gtgtttgaag gctgatgt ggctggaggc chr11:57415825-57415905 5 1.01e-03 ATTG CCTTCTGC CCACGCGCCA chr20:42319698-42319778 64 1.01e-03 CAGTTCTGGG CCTTCTGC CCTCTTTGG chr11:876095-876175 24 1.01e-03 AGGCGTCTGA GCTGATGT CGCCAGAGCT chr3:128773654-128773734 40 1.01e-03 tcagttagtc acatctgg tggaactgca chr3:129512900-129512980 49 1.01e-03 TCAGATGACA GCTGCAGT TTTAGGGGAA chr7:24903973-24904053 34 1.01e-03 tttattccat acatctgg gttgagcctg chr21:40357697-40357777 33 1.09e-03 GCCTCACCCA ACATCTGT CCTGCGGCGG chr2:127752074-127752154 71 1.09e-03 ctcttcagag acagaagg aa chr2:227700194-227700274 40 1.09e-03 TGCGATAGCT CCTGAAGC AGGAGAGTGT chr14:100038918-10003899 12 1.09e-03 GAAAGCTCTG ACATCTGT CCTTTGCTGG chr1:226298957-226299037 67 1.29e-03 tttaacaccc ccaggtgc atattt chr19:51727514-51727594 48 1.29e-03 tcttagtgca cctgaagg gaaaggaatt chr11:34258293-34258373 18 1.29e-03 AAACGAAATC GCATCAGC CGCAAAGCTG chr2:30736590-30736670 18 1.29e-03 tatctgcttg ccttctgt ggaggggcta chr20:30505819-30505899 30 1.29e-03 tcttagtgca cctgaagg gaaaggaatg chr20:33780333-33780413 47 1.29e-03 tcttagtgca cctgaagg gaaaggaatg chr12:27170378-27170458 41 1.29e-03 tcttagtgca cctgaagg gaaaggaatg chr7:104607698-104607778 1 1.38e-03 . CCAGGTGG GCTGAGTAGA chr2:209436645-209436725 35 1.47e-03 ctggtaaaaa gcatatgt cacaacaaaa chrX:134996744-134996824 7 1.82e-03 ctgcag gcaggtgt catataagag chr3:125152084-125152164 43 1.82e-03 gagctaactt gcaggtgt ctggtgatag -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SCAGCTGB MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:35309349-35309429 2.8e-05 54_[+3]_18 chr17:14064888-14064968 2.8e-05 50_[+3]_22 chr22:36764684-36764764 4.3e-05 64_[+3]_8 chr15:74902916-74902996 4.3e-05 68_[+3]_4 chr12:9039978-9040058 5.8e-05 28_[+3]_44 chrX:102356741-102356821 5.8e-05 65_[+3]_7 chr4:84417384-84417464 5.8e-05 [+3]_72 chr2:173465564-173465644 5.8e-05 62_[+3]_10 chr5:657864-657944 5.8e-05 40_[+3]_32 chr2:239331042-239331122 5.8e-05 50_[+3]_22 chr4:140364982-140365062 5.8e-05 59_[+3]_13 chr8:37939615-37939695 5.8e-05 8_[+3]_64 chr8:37949364-37949444 5.8e-05 9_[+3]_63 chr14:20645709-20645789 5.8e-05 59_[+3]_13 chr3:14162506-14162586 5.8e-05 33_[+3]_39 chr15:69276649-69276729 0.0001 64_[+3]_8 chr15:88214703-88214783 0.0001 60_[+3]_12 chr13:95923463-95923543 0.0001 40_[+3]_32 chr9:131355491-131355571 0.0001 43_[+3]_29 chr10:43140678-43140758 0.0001 48_[+3]_24 chr7:77502865-77502945 0.0001 13_[+3]_59 chr5:16418757-16418837 0.00013 43_[+3]_29 chr16:21272958-21273038 0.00013 9_[+3]_63 chr1:25606345-25606425 0.00013 44_[+3]_28 chr1:109677197-109677277 0.00016 57_[+3]_15 chr1:207809096-207809176 0.00016 20_[+3]_52 chr14:36733971-36734051 0.00016 40_[+3]_32 chr12:125369547-12536962 0.0002 14_[+3]_58 chr15:69284230-69284310 0.0002 10_[+3]_62 chrX:47543021-47543101 0.0002 57_[+3]_15 chr17:31298382-31298462 0.0002 61_[+3]_11 chr2:58916117-58916197 0.0002 65_[+3]_7 chr6:80314384-80314464 0.0002 68_[+3]_4 chr15:39432311-39432391 0.0002 16_[+3]_56 chr2:158755887-158755967 0.0002 10_[+3]_62 chr1:6489893-6489973 0.0002 27_[+3]_45 chr10:63540228-63540308 0.00025 11_[+3]_61 chr1:63156058-63156138 0.00025 48_[+3]_24 chr7:139935090-139935170 0.00025 41_[+3]_31 chr17:62971009-62971089 0.00025 30_[+3]_42 chr8:144016040-144016120 0.00025 34_[+3]_38 chr5:42873109-42873189 0.00029 33_[+3]_39 chr16:12387230-12387310 0.00029 40_[+3]_32 chr11:2000372-2000452 0.00029 39_[+3]_33 chr9:69491642-69491722 0.00029 49_[+3]_23 chr3:6582803-6582883 0.00031 39_[+3]_33 chr15:35459068-35459148 0.00034 21_[+3]_51 chr8:23366398-23366478 0.00034 23_[+3]_49 chr5:29796336-29796416 0.00034 67_[+3]_5 chr10:75004827-75004907 0.00043 2_[+3]_70 chr19:38613546-38613626 0.00043 39_[+3]_33 chr13:44972142-44972222 0.00043 71_[+3]_1 chr12:108879357-10887943 0.00043 44_[+3]_28 chr9:4862954-4863034 0.00043 15_[+3]_57 chr1:25739906-25739986 0.00043 21_[+3]_51 chr20:9129847-9129927 0.00043 22_[+3]_50 chr1:211395919-211395999 0.00043 29_[+3]_43 chr1:224058441-224058521 0.00043 26_[+3]_46 chr19:381064-381144 0.00043 [+3]_72 chr1:16380765-16380845 0.00047 31_[+3]_41 chr8:2645844-2645924 0.00047 11_[+3]_61 chr8:101776304-101776384 0.00054 65_[+3]_7 chr9:100987560-100987640 0.00054 6_[+3]_66 chr7:102082194-102082274 0.00054 23_[+3]_49 chr6:13381105-13381185 0.00054 61_[+3]_11 chr18:43733358-43733438 0.00054 49_[+3]_23 chr10:19024850-19024930 0.00054 53_[+3]_19 chr17:26854455-26854535 0.00054 38_[+3]_34 chr16:10437118-10437198 0.00054 13_[+3]_59 chr13:19398967-19399047 0.00054 60_[+3]_12 chr10:43142681-43142761 0.00054 26_[+3]_46 chr5:139990841-139990921 0.00054 15_[+3]_57 chr19:516716-516796 0.00054 26_[+3]_46 chr14:35122449-35122529 0.00054 29_[+3]_43 chr7:127478999-127479079 0.00062 21_[+3]_51 chr15:75987015-75987095 0.00062 38_[+3]_34 chr14:24725570-24725650 0.00062 71_[+3]_1 chr6:159303106-159303186 0.00062 37_[+3]_35 chr1:228608967-228609047 0.00062 6_[+3]_66 chr1:27118210-27118290 0.0007 19_[+3]_53 chr19:6682880-6682960 0.0007 52_[+3]_20 chr16:21548249-21548329 0.0007 54_[+3]_18 chr3:141567989-141568069 0.00074 60_[+3]_12 chr17:62919226-62919306 0.00079 58_[+3]_14 chr4:154449959-154450039 0.00083 46_[+3]_26 chr6:34249867-34249947 0.00092 12_[+3]_60 chr17:19913648-19913728 0.00092 9_[+3]_63 chr5:32288424-32288504 0.00092 5_[+3]_67 chr4:68418029-68418109 0.00092 16_[+3]_56 chr11:62645227-62645307 0.001 16_[+3]_56 chr11:57415825-57415905 0.001 4_[+3]_68 chr20:42319698-42319778 0.001 63_[+3]_9 chr11:876095-876175 0.001 23_[+3]_49 chr3:128773654-128773734 0.001 39_[+3]_33 chr3:129512900-129512980 0.001 48_[+3]_24 chr7:24903973-24904053 0.001 33_[+3]_39 chr21:40357697-40357777 0.0011 32_[+3]_40 chr2:127752074-127752154 0.0011 70_[+3]_2 chr2:227700194-227700274 0.0011 39_[+3]_33 chr14:100038918-10003899 0.0011 11_[+3]_61 chr1:226298957-226299037 0.0013 66_[+3]_6 chr19:51727514-51727594 0.0013 47_[+3]_25 chr11:34258293-34258373 0.0013 17_[+3]_55 chr2:30736590-30736670 0.0013 17_[+3]_55 chr20:30505819-30505899 0.0013 29_[+3]_43 chr20:33780333-33780413 0.0013 46_[+3]_26 chr12:27170378-27170458 0.0013 40_[+3]_32 chr7:104607698-104607778 0.0014 [+3]_72 chr2:209436645-209436725 0.0015 34_[+3]_38 chrX:134996744-134996824 0.0018 6_[+3]_66 chr3:125152084-125152164 0.0018 42_[+3]_30 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SCAGCTGB MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF SCAGCTGB width=8 seqs=111 chr1:35309349-35309429 ( 55) CCAGCTGG 1 chr17:14064888-14064968 ( 51) CCAGCTGG 1 chr22:36764684-36764764 ( 65) CCAGCTGT 1 chr15:74902916-74902996 ( 69) CCAGCTGT 1 chr12:9039978-9040058 ( 29) GCAGCTGC 1 chrX:102356741-102356821 ( 66) GCAGCTGC 1 chr4:84417384-84417464 ( 1) GCAGCTGC 1 chr2:173465564-173465644 ( 63) GCAGCTGC 1 chr5:657864-657944 ( 41) GCAGCTGC 1 chr2:239331042-239331122 ( 51) GCAGCTGC 1 chr4:140364982-140365062 ( 60) GCAGCTGC 1 chr8:37939615-37939695 ( 9) GCAGCTGC 1 chr8:37949364-37949444 ( 10) GCAGCTGC 1 chr14:20645709-20645789 ( 60) GCAGCTGC 1 chr3:14162506-14162586 ( 34) GCAGCTGC 1 chr15:69276649-69276729 ( 65) ACAGCTGC 1 chr15:88214703-88214783 ( 61) ACAGCTGC 1 chr13:95923463-95923543 ( 41) ACAGCTGC 1 chr9:131355491-131355571 ( 44) GCAGCTGT 1 chr10:43140678-43140758 ( 49) ACAGCTGC 1 chr7:77502865-77502945 ( 14) ACAGCTGC 1 chr5:16418757-16418837 ( 44) CCAGATGC 1 chr16:21272958-21273038 ( 10) CCAGCAGC 1 chr1:25606345-25606425 ( 45) CCAGCAGC 1 chr1:109677197-109677277 ( 58) CCTGCTGC 1 chr1:207809096-207809176 ( 21) CCTGCTGC 1 chr14:36733971-36734051 ( 41) CCTGCTGC 1 chr12:125369547-12536962 ( 15) CCAGATGG 1 chr15:69284230-69284310 ( 11) CCAGATGG 1 chrX:47543021-47543101 ( 58) CCAGCAGG 1 chr17:31298382-31298462 ( 62) ACAGCTGT 1 chr2:58916117-58916197 ( 66) ACAGCTGT 1 chr6:80314384-80314464 ( 69) CCAGATGG 1 chr15:39432311-39432391 ( 17) ACAGCTGT 1 chr2:158755887-158755967 ( 11) CCAGATGG 1 chr1:6489893-6489973 ( 28) CCAGATGG 1 chr10:63540228-63540308 ( 12) CCAGATGT 1 chr1:63156058-63156138 ( 49) CCAGATGT 1 chr7:139935090-139935170 ( 42) CCAGCAGT 1 chr17:62971009-62971089 ( 31) CCAGATGT 1 chr8:144016040-144016120 ( 35) CCAGATGT 1 chr5:42873109-42873189 ( 34) GCAGCAGC 1 chr16:12387230-12387310 ( 41) CCTGCTGT 1 chr11:2000372-2000452 ( 40) CCTGCTGT 1 chr9:69491642-69491722 ( 50) CCTGCTGT 1 chr3:6582803-6582883 ( 40) GCTGCTGC 1 chr15:35459068-35459148 ( 22) GCAGCAGG 1 chr8:23366398-23366478 ( 24) GCAGATGG 1 chr5:29796336-29796416 ( 68) GCAGATGG 1 chr10:75004827-75004907 ( 3) GCAGATGT 1 chr19:38613546-38613626 ( 40) CCATCTGC 1 chr13:44972142-44972222 ( 72) GCAGATGT 1 chr12:108879357-10887943 ( 45) CCATCTGC 1 chr9:4862954-4863034 ( 16) GCAGCAGT 1 chr1:25739906-25739986 ( 22) GCTGCTGG 1 chr20:9129847-9129927 ( 23) ACAGCAGC 1 chr1:211395919-211395999 ( 30) ACAGATGC 1 chr1:224058441-224058521 ( 27) ACAGCAGC 1 chr19:381064-381144 ( 1) GCAGATGT 1 chr1:16380765-16380845 ( 32) GCTGCTGT 1 chr8:2645844-2645924 ( 12) ACTGCTGC 1 chr8:101776304-101776384 ( 66) CCATCTGG 1 chr9:100987560-100987640 ( 7) CCATCTGG 1 chr7:102082194-102082274 ( 24) CCATCTGG 1 chr6:13381105-13381185 ( 62) CCTGCAGC 1 chr18:43733358-43733438 ( 50) CCTGATGC 1 chr10:19024850-19024930 ( 54) ACAGCAGG 1 chr17:26854455-26854535 ( 39) ACAGCAGG 1 chr16:10437118-10437198 ( 14) CCATCTGG 1 chr13:19398967-19399047 ( 61) CCTGCAGC 1 chr10:43142681-43142761 ( 27) CCTGATGC 1 chr5:139990841-139990921 ( 16) CCTGCAGC 1 chr19:516716-516796 ( 27) CCTGCAGC 1 chr14:35122449-35122529 ( 30) ACAGATGG 1 chr7:127478999-127479079 ( 22) ACAGCAGT 1 chr15:75987015-75987095 ( 39) ACTGCTGG 1 chr14:24725570-24725650 ( 72) CCATCTGT 1 chr6:159303106-159303186 ( 38) CCATCTGT 1 chr1:228608967-228609047 ( 7) CCAGAAGG 1 chr1:27118210-27118290 ( 20) CCTGCAGG 1 chr19:6682880-6682960 ( 53) CCAGAAGT 1 chr16:21548249-21548329 ( 55) ACTGCTGT 1 chr3:141567989-141568069 ( 61) GCAGAAGC 1 chr17:62919226-62919306 ( 59) GCATCTGG 1 chr4:154449959-154450039 ( 47) ACATCTGC 1 chr6:34249867-34249947 ( 13) GCTGCAGG 1 chr17:19913648-19913728 ( 10) GCTGCAGG 1 chr5:32288424-32288504 ( 6) CCATCAGC 1 chr4:68418029-68418109 ( 17) GCTGCAGG 1 chr11:62645227-62645307 ( 17) GCTGATGT 1 chr11:57415825-57415905 ( 5) CCTTCTGC 1 chr20:42319698-42319778 ( 64) CCTTCTGC 1 chr11:876095-876175 ( 24) GCTGATGT 1 chr3:128773654-128773734 ( 40) ACATCTGG 1 chr3:129512900-129512980 ( 49) GCTGCAGT 1 chr7:24903973-24904053 ( 34) ACATCTGG 1 chr21:40357697-40357777 ( 33) ACATCTGT 1 chr2:127752074-127752154 ( 71) ACAGAAGG 1 chr2:227700194-227700274 ( 40) CCTGAAGC 1 chr14:100038918-10003899 ( 12) ACATCTGT 1 chr1:226298957-226299037 ( 67) CCAGGTGC 1 chr19:51727514-51727594 ( 48) CCTGAAGG 1 chr11:34258293-34258373 ( 18) GCATCAGC 1 chr2:30736590-30736670 ( 18) CCTTCTGT 1 chr20:30505819-30505899 ( 30) CCTGAAGG 1 chr20:33780333-33780413 ( 47) CCTGAAGG 1 chr12:27170378-27170458 ( 41) CCTGAAGG 1 chr7:104607698-104607778 ( 1) CCAGGTGG 1 chr2:209436645-209436725 ( 35) GCATATGT 1 chrX:134996744-134996824 ( 7) GCAGGTGT 1 chr3:125152084-125152164 ( 43) GCAGGTGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SCAGCTGB MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.02356 E= 1.5e-014 -19 96 33 -1344 -1344 205 -1344 -1344 151 -1344 -1344 19 -1344 -1344 171 -53 18 150 -280 -1344 22 -1344 -1344 145 -1344 -1344 200 -1344 -1344 71 29 19 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SCAGCTGB MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 111 E= 1.5e-014 0.216216 0.468468 0.315315 0.000000 0.000000 1.000000 0.000000 0.000000 0.702703 0.000000 0.000000 0.297297 0.000000 0.000000 0.819820 0.180180 0.279279 0.684685 0.036036 0.000000 0.288288 0.000000 0.000000 0.711712 0.000000 0.000000 1.000000 0.000000 0.000000 0.396396 0.306306 0.297297 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SCAGCTGB MEME-3 regular expression -------------------------------------------------------------------------------- [CGA]C[AT]G[CA][TA]G[CGT] -------------------------------------------------------------------------------- Time 12.10 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTAGCTT MEME-4 width = 8 sites = 13 llr = 130 E-value = 6.3e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTAGCTT MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::a:::: pos.-specific C :2:::a2: probability G ::::a::: matrix T a8a:::8a bits 2.0 *** 1.8 * **** * 1.6 * **** * 1.4 * ****** Relative 1.2 ******** Entropy 1.0 ******** (14.4 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTTAGCTT consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTAGCTT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:51727514-51727594 25 1.82e-05 tgagtctgct tttagctt ccctatctta chr4:84417384-84417464 31 1.82e-05 caagtctgct tttagctt ctctatctta chr20:30505819-30505899 7 1.82e-05 gttgct tttagctt tcctatctta chr5:175624414-175624494 51 1.82e-05 ccgagtctgc tttagctt ccctatctta chr4:68418029-68418109 45 1.82e-05 cgagtctgct tttagctt ccctatctta chr5:139990841-139990921 66 1.82e-05 ccagtctgct tttagctt ccctatc chrX:79767986-79768066 2 1.82e-05 t tttagctt ccctatctta chr20:33780333-33780413 24 1.82e-05 ccgggttgct tttagctt ccctatctta chr3:14162506-14162586 65 1.82e-05 caagactgct tttagctt ccctatct chr12:27170378-27170458 18 1.82e-05 cgagtctgct tttagctt ccctatctta chr11:124537653-12453773 16 3.50e-05 TCCCATAACT TCTAGCTT TGCCTCCTCC chr21:47875773-47875853 22 6.75e-05 cattccaacc tctagcct ctgaactgct chr20:9129847-9129927 71 6.75e-05 gtcagttggc tctagcct ct -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTAGCTT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:51727514-51727594 1.8e-05 24_[+4]_48 chr4:84417384-84417464 1.8e-05 30_[+4]_42 chr20:30505819-30505899 1.8e-05 6_[+4]_66 chr5:175624414-175624494 1.8e-05 50_[+4]_22 chr4:68418029-68418109 1.8e-05 44_[+4]_28 chr5:139990841-139990921 1.8e-05 65_[+4]_7 chrX:79767986-79768066 1.8e-05 1_[+4]_71 chr20:33780333-33780413 1.8e-05 23_[+4]_49 chr3:14162506-14162586 1.8e-05 64_[+4]_8 chr12:27170378-27170458 1.8e-05 17_[+4]_55 chr11:124537653-12453773 3.5e-05 15_[+4]_57 chr21:47875773-47875853 6.7e-05 21_[+4]_51 chr20:9129847-9129927 6.7e-05 70_[+4]_2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTAGCTT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTAGCTT width=8 seqs=13 chr19:51727514-51727594 ( 25) TTTAGCTT 1 chr4:84417384-84417464 ( 31) TTTAGCTT 1 chr20:30505819-30505899 ( 7) TTTAGCTT 1 chr5:175624414-175624494 ( 51) TTTAGCTT 1 chr4:68418029-68418109 ( 45) TTTAGCTT 1 chr5:139990841-139990921 ( 66) TTTAGCTT 1 chrX:79767986-79768066 ( 2) TTTAGCTT 1 chr20:33780333-33780413 ( 24) TTTAGCTT 1 chr3:14162506-14162586 ( 65) TTTAGCTT 1 chr12:27170378-27170458 ( 18) TTTAGCTT 1 chr11:124537653-12453773 ( 16) TCTAGCTT 1 chr21:47875773-47875853 ( 22) TCTAGCCT 1 chr20:9129847-9129927 ( 71) TCTAGCCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTAGCTT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.2095 E= 6.3e+002 -1035 -1035 -1035 194 -1035 -7 -1035 156 -1035 -1035 -1035 194 202 -1035 -1035 -1035 -1035 -1035 200 -1035 -1035 205 -1035 -1035 -1035 -65 -1035 170 -1035 -1035 -1035 194 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTAGCTT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 13 E= 6.3e+002 0.000000 0.000000 0.000000 1.000000 0.000000 0.230769 0.000000 0.769231 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.153846 0.000000 0.846154 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTAGCTT MEME-4 regular expression -------------------------------------------------------------------------------- T[TC]TAGCTT -------------------------------------------------------------------------------- Time 15.31 secs. ******************************************************************************** ******************************************************************************** MOTIF GGGAGGYA MEME-5 width = 8 sites = 24 llr = 209 E-value = 1.1e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif GGGAGGYA MEME-5 Description -------------------------------------------------------------------------------- Simplified A 2::a1::7 pos.-specific C ::::::5: probability G 8aa:9a13 matrix T ::::::4: bits 2.0 *** * 1.8 *** * 1.6 *** * 1.4 ****** Relative 1.2 ****** * Entropy 1.0 ****** * (12.5 bits) 0.8 ****** * 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GGGAGGCA consensus TG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGYA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:66655618-66655698 73 1.47e-05 TAAAAAGGCA GGGAGGCA chr21:40357697-40357777 14 1.47e-05 ATGTTTGCGT GGGAGGCA AGCCTCACCC chr4:145061885-145061965 43 1.47e-05 TGATAGGCAG GGGAGGCA TTTTAAATGA chr4:144826768-144826848 32 1.47e-05 TGATAGGCAG GGGAGGCA TTTTAAATGA chr4:144940562-144940642 18 1.47e-05 TGATAGGCAG GGGAGGCA TTTTAAATGA chr8:37949364-37949444 22 3.06e-05 agctgcgcta gggaggta aagcaggaac chr19:516716-516796 42 3.06e-05 agccgtgcta gggaggta agcaggaact chrX:102356741-102356821 43 4.55e-05 agcagactca gggaggcg gcggggggta chr11:57415825-57415905 64 6.16e-05 AGGATAAGAA GGGAGGTG GCCCCTGTT chr20:42319698-42319778 44 6.16e-05 ccaaggctta gggaggtg aaCAGTTCTG chr22:36764684-36764764 26 6.16e-05 TAACAGTGCT GGGAGGTG GAGGAGTGTT chrX:47543021-47543101 46 6.16e-05 tgtccgttgg gggaggtg gtcaccagca chr3:6582803-6582883 3 6.16e-05 ca gggaggtg ggggttttat chr8:37939615-37939695 21 6.16e-05 agctgcgcta gggaggtg aagcaggaac chr1:243269310-243269390 71 7.69e-05 cacacgttgt gggaggga cc chr11:16878928-16879008 45 7.69e-05 GCTCCCCACT GGGAGGGA GAATGTCACC chr1:65487638-65487718 68 7.69e-05 GGTGACTCAA GGGAGGGA GGAAT chr12:108879357-10887943 60 9.14e-05 tgcaaaacca aggaggca agcctcacca chr10:19024850-19024930 5 9.14e-05 CACC AGGAGGCA GAGTAGATAA chr3:57584942-57585022 48 9.14e-05 gcctctccaa aggaggca gtcagatatg chr11:16626424-16626504 41 1.06e-04 CGGAGCGCCG GGGAAGCA GCCCGGCACC chr1:35309349-35309429 23 1.06e-04 AAGACAGCTG GGGAAGCA GGGAGGCCTC chr7:102082194-102082274 10 1.06e-04 agctgCAGT GGGAAGCA AGTGAACCAT chr1:95581314-95581394 67 1.21e-04 GAGTTTCTGT AGGAGGTA GTGTTG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGYA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:66655618-66655698 1.5e-05 72_[+5] chr21:40357697-40357777 1.5e-05 13_[+5]_59 chr4:145061885-145061965 1.5e-05 42_[+5]_30 chr4:144826768-144826848 1.5e-05 31_[+5]_41 chr4:144940562-144940642 1.5e-05 17_[+5]_55 chr8:37949364-37949444 3.1e-05 21_[+5]_51 chr19:516716-516796 3.1e-05 41_[+5]_31 chrX:102356741-102356821 4.6e-05 42_[+5]_30 chr11:57415825-57415905 6.2e-05 63_[+5]_9 chr20:42319698-42319778 6.2e-05 43_[+5]_29 chr22:36764684-36764764 6.2e-05 25_[+5]_47 chrX:47543021-47543101 6.2e-05 45_[+5]_27 chr3:6582803-6582883 6.2e-05 2_[+5]_70 chr8:37939615-37939695 6.2e-05 20_[+5]_52 chr1:243269310-243269390 7.7e-05 70_[+5]_2 chr11:16878928-16879008 7.7e-05 44_[+5]_28 chr1:65487638-65487718 7.7e-05 67_[+5]_5 chr12:108879357-10887943 9.1e-05 59_[+5]_13 chr10:19024850-19024930 9.1e-05 4_[+5]_68 chr3:57584942-57585022 9.1e-05 47_[+5]_25 chr11:16626424-16626504 0.00011 40_[+5]_32 chr1:35309349-35309429 0.00011 22_[+5]_50 chr7:102082194-102082274 0.00011 9_[+5]_63 chr1:95581314-95581394 0.00012 66_[+5]_6 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGYA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GGGAGGYA width=8 seqs=24 chr8:66655618-66655698 ( 73) GGGAGGCA 1 chr21:40357697-40357777 ( 14) GGGAGGCA 1 chr4:145061885-145061965 ( 43) GGGAGGCA 1 chr4:144826768-144826848 ( 32) GGGAGGCA 1 chr4:144940562-144940642 ( 18) GGGAGGCA 1 chr8:37949364-37949444 ( 22) GGGAGGTA 1 chr19:516716-516796 ( 42) GGGAGGTA 1 chrX:102356741-102356821 ( 43) GGGAGGCG 1 chr11:57415825-57415905 ( 64) GGGAGGTG 1 chr20:42319698-42319778 ( 44) GGGAGGTG 1 chr22:36764684-36764764 ( 26) GGGAGGTG 1 chrX:47543021-47543101 ( 46) GGGAGGTG 1 chr3:6582803-6582883 ( 3) GGGAGGTG 1 chr8:37939615-37939695 ( 21) GGGAGGTG 1 chr1:243269310-243269390 ( 71) GGGAGGGA 1 chr11:16878928-16879008 ( 45) GGGAGGGA 1 chr1:65487638-65487718 ( 68) GGGAGGGA 1 chr12:108879357-10887943 ( 60) AGGAGGCA 1 chr10:19024850-19024930 ( 5) AGGAGGCA 1 chr3:57584942-57585022 ( 48) AGGAGGCA 1 chr11:16626424-16626504 ( 41) GGGAAGCA 1 chr1:35309349-35309429 ( 23) GGGAAGCA 1 chr7:102082194-102082274 ( 10) GGGAAGCA 1 chr1:95581314-95581394 ( 67) AGGAGGTA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGYA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.2272 E= 1.1e+003 -57 -1123 173 -1123 -1123 -1123 200 -1123 -1123 -1123 200 -1123 202 -1123 -1123 -1123 -98 -1123 180 -1123 -1123 -1123 200 -1123 -1123 105 -100 52 152 -1123 22 -1123 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGYA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 24 E= 1.1e+003 0.166667 0.000000 0.833333 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.125000 0.000000 0.875000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.500000 0.125000 0.375000 0.708333 0.000000 0.291667 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGGAGGYA MEME-5 regular expression -------------------------------------------------------------------------------- GGGAGG[CT][AG] -------------------------------------------------------------------------------- Time 18.56 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:381064-381144 7.29e-03 80 chr14:88491087-88491167 7.81e-02 69_[+1(1.51e-05)]_3 chr6:10750103-10750183 7.37e-03 48_[+2(6.81e-05)]_24 chr7:7082284-7082364 3.31e-02 80 chr6:160992404-160992484 6.86e-02 80 chr8:144016040-144016120 4.83e-02 80 chr17:62919226-62919306 3.18e-01 80 chr12:27170378-27170458 8.15e-04 17_[+4(1.82e-05)]_55 chr11:124537653-12453773 6.35e-03 15_[+4(3.50e-05)]_26_[+2(6.81e-05)]_\ 23 chr14:35122449-35122529 7.75e-03 80 chr1:224058441-224058521 1.14e-03 80 chr1:211395919-211395999 1.10e-02 42_[+2(5.06e-05)]_30 chr4:144940562-144940642 8.32e-03 17_[+5(1.47e-05)]_55 chr14:23366712-23366792 7.58e-03 17_[+1(3.05e-05)]_55 chr1:25611725-25611805 5.00e-01 80 chrX:47535543-47535623 8.39e-03 80 chr3:14162506-14162586 1.15e-04 33_[+3(5.78e-05)]_23_[+4(1.82e-05)]_\ 8 chr20:33780333-33780413 6.58e-04 23_[+4(1.82e-05)]_49 chr19:516716-516796 1.09e-02 41_[+5(3.06e-05)]_31 chr10:7049687-7049767 4.41e-01 80 chr2:208825012-208825092 4.67e-02 80 chr1:160919166-160919246 3.47e-01 80 chr11:62136574-62136654 2.62e-01 80 chrX:79767986-79768066 3.78e-03 1_[+4(1.82e-05)]_71 chr14:36733971-36734051 2.61e-02 80 chr4:99722527-99722607 1.03e-01 80 chr3:57584942-57585022 3.98e-04 47_[+5(9.14e-05)]_25 chr5:139990841-139990921 8.32e-03 65_[+4(1.82e-05)]_7 chr1:25606345-25606425 1.60e-02 80 chr9:69491642-69491722 1.16e-03 26_[+1(1.51e-05)]_46 chr7:5123118-5123198 6.48e-02 80 chr3:177148569-177148649 1.46e-01 80 chr8:38068319-38068399 2.95e-02 80 chr1:191793077-191793157 9.85e-02 80 chr5:134528296-134528376 3.08e-02 71_[+2(3.31e-05)]_1 chr3:32115899-32115979 4.50e-03 16_[+2(6.81e-05)]_56 chr19:35411451-35411531 3.16e-01 80 chr9:136159295-136159375 2.70e-01 80 chr5:176075746-176075826 4.33e-01 80 chr4:1884777-1884857 3.43e-01 80 chr1:6489893-6489973 6.01e-02 80 chr1:207020985-207021065 1.81e-01 53_[+1(6.13e-05)]_19 chr4:68418029-68418109 9.13e-04 44_[+4(1.82e-05)]_28 chr10:43142681-43142761 1.29e-01 80 chr20:9129847-9129927 7.03e-03 70_[+4(6.75e-05)]_2 chr4:144826768-144826848 4.40e-03 31_[+5(1.47e-05)]_41 chr2:240008152-240008232 2.02e-01 80 chr11:61109833-61109913 2.91e-01 80 chr17:62971009-62971089 2.79e-03 80 chr1:228608967-228609047 1.78e-02 80 chr6:159303106-159303186 4.72e-03 80 chr2:158755887-158755967 1.85e-02 80 chr12:53703911-53703991 5.77e-01 80 chr9:132875219-132875299 9.74e-01 80 chr16:9171927-9172007 2.59e-02 [+1(9.07e-05)]_72 chr8:2645844-2645924 3.63e-02 80 chr14:24725570-24725650 5.44e-02 80 chr7:77502865-77502945 2.19e-04 80 chr14:20645709-20645789 9.38e-04 38_[+2(3.31e-05)]_13_[+3(5.78e-05)]_\ 13 chr11:2000372-2000452 6.98e-02 80 chrX:47572287-47572367 6.68e-03 63_[+1(3.05e-05)]_9 chr8:37949364-37949444 1.17e-03 9_[+3(5.78e-05)]_4_[+5(3.06e-05)]_\ 51 chr15:39432311-39432391 2.04e-02 6_[+1(6.13e-05)]_66 chr10:43140678-43140758 1.48e-01 80 chr11:118306980-11830706 3.73e-01 80 chr12:28345242-28345322 4.06e-01 80 chr7:139935090-139935170 3.37e-01 80 chr5:175624414-175624494 1.83e-03 50_[+4(1.82e-05)]_22 chr1:65487638-65487718 1.12e-02 67_[+5(7.69e-05)]_5 chr8:37939615-37939695 7.28e-03 8_[+3(5.78e-05)]_4_[+5(6.16e-05)]_\ 52 chr4:140364982-140365062 1.09e-02 59_[+3(5.78e-05)]_13 chr14:100038918-10003899 2.87e-02 80 chr13:19398967-19399047 5.12e-03 24_[+1(3.05e-05)]_48 chr9:125209218-125209298 2.40e-01 80 chr1:151687984-151688064 2.10e-03 35_[+3(1.39e-05)]_37 chr15:75987015-75987095 4.91e-02 80 chr9:102907620-102907700 6.62e-02 11_[+1(1.51e-05)]_33_[+1(1.51e-05)]_\ 20 chr13:50420835-50420915 4.11e-03 71_[+2(1.62e-05)]_1 chr16:10437118-10437198 9.94e-03 41_[+1(4.53e-05)]_31 chr6:80314384-80314464 9.46e-03 80 chr5:32288424-32288504 2.32e-02 80 chr7:24903973-24904053 6.32e-02 80 chr1:95581314-95581394 5.01e-02 80 chr4:145000047-145000127 5.44e-03 80 chr3:6582803-6582883 4.50e-05 2_[+5(6.16e-05)]_70 chr6:129984391-129984471 1.54e-01 80 chr16:10591143-10591223 8.37e-01 80 chr1:25739906-25739986 2.16e-02 64_[+1(6.13e-05)]_8 chr2:128300692-128300772 2.86e-01 80 chr20:30505819-30505899 1.03e-03 6_[+4(1.82e-05)]_66 chr16:21548249-21548329 1.19e-03 36_[+1(3.05e-05)]_36 chr2:30736590-30736670 1.57e-02 67_[+2(5.06e-05)]_5 chr9:4862954-4863034 5.09e-02 80 chr2:239331042-239331122 9.50e-03 50_[+3(5.78e-05)]_22 chr9:128239615-128239695 9.32e-02 71_[+1(3.05e-05)]_1 chr10:13747877-13747957 2.41e-02 80 chrX:55054624-55054704 2.48e-01 80 chr3:196715536-196715616 7.10e-01 80 chr1:63156058-63156138 1.18e-02 63_[+2(6.81e-05)]_9 chr4:103277041-103277121 9.80e-03 80 chr6:16263876-16263956 1.02e-01 13_[+1(1.51e-05)]_34_[+1(1.51e-05)]_\ 17 chr5:657864-657944 5.29e-03 40_[+3(5.78e-05)]_32 chr6:10725441-10725521 1.70e-03 49_[+2(6.81e-05)]_23 chr3:125152084-125152164 1.18e-01 80 chr4:25052509-25052589 1.52e-01 80 chr9:131355491-131355571 8.33e-03 17_[+2(3.31e-05)]_55 chr20:3890846-3890926 6.35e-01 80 chr17:73444681-73444761 1.06e-03 [+4(3.50e-05)]_72 chr15:74902916-74902996 9.11e-03 68_[+3(4.34e-05)]_4 chr17:19913648-19913728 1.20e-02 80 chr17:14064888-14064968 4.65e-03 50_[+3(2.84e-05)]_22 chr6:112126190-112126270 1.14e-01 80 chr3:129512900-129512980 4.81e-03 80 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9_[+2(1.62e-05)]_63 chr17:52938595-52938675 7.91e-02 80 chr2:122292306-122292386 8.26e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n04.farnam.hpc.yale.internal ********************************************************************************