******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/CBFA2T2.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr4:10497402-10497482 1.0000 80 chr19:381064-381144 1.0000 80 chr14:88491088-88491168 1.0000 80 chr7:7082287-7082367 1.0000 80 chr17:7137857-7137937 1.0000 80 chr8:144016038-144016118 1.0000 80 chr19:3990351-3990431 1.0000 80 chr7:154467934-154468014 1.0000 80 chr13:49684356-49684436 1.0000 80 chr10:47619242-47619322 1.0000 80 chr1:224058442-224058522 1.0000 80 chr2:158755881-158755961 1.0000 80 chr4:144940569-144940649 1.0000 80 chr10:70883886-70883966 1.0000 80 chr14:20923291-20923371 1.0000 80 chr14:100038917-10003899 1.0000 80 chr1:6489896-6489976 1.0000 80 chr6:160992403-160992483 1.0000 80 chr14:35122459-35122539 1.0000 80 chr11:61370697-61370777 1.0000 80 chr19:40854416-40854496 1.0000 80 chr17:62919223-62919303 1.0000 80 chr12:27170378-27170458 1.0000 80 chr3:14162510-14162590 1.0000 80 chrX:47535553-47535633 1.0000 80 chr11:2000378-2000458 1.0000 80 chr17:6915640-6915720 1.0000 80 chr17:72329122-72329202 1.0000 80 chr15:75987054-75987134 1.0000 80 chr1:25611725-25611805 1.0000 80 chr3:6582811-6582891 1.0000 80 chr17:11876223-11876303 1.0000 80 chr1:211395914-211395994 1.0000 80 chr3:32115895-32115975 1.0000 80 chr9:69491640-69491720 1.0000 80 chr12:32207214-32207294 1.0000 80 chr15:39432301-39432381 1.0000 80 chr9:131355492-131355572 1.0000 80 chr6:10750099-10750179 1.0000 80 chr1:207020987-207021067 1.0000 80 chr5:134528307-134528387 1.0000 80 chr7:139935100-139935180 1.0000 80 chr14:23366707-23366787 1.0000 80 chr2:240008152-240008232 1.0000 80 chr1:25606344-25606424 1.0000 80 chr14:36733973-36734053 1.0000 80 chr19:49457982-49458062 1.0000 80 chr1:151687987-151688067 1.0000 80 chr4:99722520-99722600 1.0000 80 chr8:38068316-38068396 1.0000 80 chr5:139990836-139990916 1.0000 80 chr11:124537648-12453772 1.0000 80 chr1:160919142-160919222 1.0000 80 chr20:9129848-9129928 1.0000 80 chr2:208825011-208825091 1.0000 80 chr20:33780330-33780410 1.0000 80 chr1:16380761-16380841 1.0000 80 chr16:57220078-57220158 1.0000 80 chr13:99628350-99628430 1.0000 80 chr16:10437114-10437194 1.0000 80 chr3:129512923-129513003 1.0000 80 chr7:24903955-24904035 1.0000 80 chrX:79767985-79768065 1.0000 80 chr4:144826776-144826856 1.0000 80 chr11:34258304-34258384 1.0000 80 chr19:516724-516804 1.0000 80 chr1:95100699-95100779 1.0000 80 chr7:5123114-5123194 1.0000 80 chr9:125209230-125209310 1.0000 80 chr17:31298383-31298463 1.0000 80 chr19:35411464-35411544 1.0000 80 chr8:98790773-98790853 1.0000 80 chr1:228608968-228609048 1.0000 80 chr2:173465552-173465632 1.0000 80 chr12:65153196-65153276 1.0000 80 chr6:80314382-80314462 1.0000 80 chr1:228366648-228366728 1.0000 80 chr9:102907625-102907705 1.0000 80 chrX:114557050-114557130 1.0000 80 chr12:125369563-12536964 1.0000 80 chr2:239331054-239331134 1.0000 80 chr17:62971008-62971088 1.0000 80 chr4:103277044-103277124 1.0000 80 chr7:77502862-77502942 1.0000 80 chr4:84417384-84417464 1.0000 80 chr1:155188793-155188873 1.0000 80 chr10:46222589-46222669 1.0000 80 chr5:112420676-112420756 1.0000 80 chr4:1884770-1884850 1.0000 80 chr5:29796334-29796414 1.0000 80 chrX:55054625-55054705 1.0000 80 chr15:74902909-74902989 1.0000 80 chr3:177148568-177148648 1.0000 80 chr7:916018-916098 1.0000 80 chr5:176075751-176075831 1.0000 80 chr10:63540225-63540305 1.0000 80 chr17:14064895-14064975 1.0000 80 chr15:93160909-93160989 1.0000 80 chr3:196715531-196715611 1.0000 80 chr1:191793071-191793151 1.0000 80 chr3:128773648-128773728 1.0000 80 chr9:136159287-136159367 1.0000 80 chr5:32288427-32288507 1.0000 80 chr13:50420831-50420911 1.0000 80 chr17:46625711-46625791 1.0000 80 chr13:44956980-44957060 1.0000 80 chr14:20645711-20645791 1.0000 80 chr1:109677202-109677282 1.0000 80 chr19:12833507-12833587 1.0000 80 chr13:44972146-44972226 1.0000 80 chr16:28503368-28503448 1.0000 80 chr16:10591142-10591222 1.0000 80 chr1:110881786-110881866 1.0000 80 chr22:31365122-31365202 1.0000 80 chr8:37949357-37949437 1.0000 80 chr1:11866206-11866286 1.0000 80 chr4:69730316-69730396 1.0000 80 chr20:3890852-3890932 1.0000 80 chr7:104607707-104607787 1.0000 80 chr5:150827102-150827182 1.0000 80 chr14:24725550-24725630 1.0000 80 chr16:8688308-8688388 1.0000 80 chr11:126081591-12608167 1.0000 80 chr10:43140672-43140752 1.0000 80 chr1:65487632-65487712 1.0000 80 chr1:35602536-35602616 1.0000 80 chr6:16263874-16263954 1.0000 80 chr6:159303111-159303191 1.0000 80 chrX:47543023-47543103 1.0000 80 chr10:13747870-13747950 1.0000 80 chr16:14491344-14491424 1.0000 80 chr4:164108621-164108701 1.0000 80 chr11:27223269-27223349 1.0000 80 chr21:45937290-45937370 1.0000 80 chr10:75690637-75690717 1.0000 80 chr1:155211032-155211112 1.0000 80 chr1:25739903-25739983 1.0000 80 chr19:7587441-7587521 1.0000 80 chr4:25052516-25052596 1.0000 80 chr6:112126195-112126275 1.0000 80 chr2:17899104-17899184 1.0000 80 chrX:134996744-134996824 1.0000 80 chr6:152554081-152554161 1.0000 80 chr9:117349941-117350021 1.0000 80 chr18:9848292-9848372 1.0000 80 chr6:164767856-164767936 1.0000 80 chr4:68418038-68418118 1.0000 80 chr5:175624406-175624486 1.0000 80 chr8:37939618-37939698 1.0000 80 chr20:32007072-32007152 1.0000 80 chr7:102082187-102082267 1.0000 80 chrX:47572300-47572380 1.0000 80 chr5:1067949-1068029 1.0000 80 chr3:125152082-125152162 1.0000 80 chr12:51762652-51762732 1.0000 80 chr12:120755546-12075562 1.0000 80 chr12:108879359-10887943 1.0000 80 chr3:142337821-142337901 1.0000 80 chr19:41256412-41256492 1.0000 80 chr1:70005908-70005988 1.0000 80 chr2:25479546-25479626 1.0000 80 chr20:30505828-30505908 1.0000 80 chr22:35608152-35608232 1.0000 80 chr12:58146255-58146335 1.0000 80 chr19:38613549-38613629 1.0000 80 chr13:44961220-44961300 1.0000 80 chr15:31270664-31270744 1.0000 80 chr1:95581308-95581388 1.0000 80 chr17:26854456-26854536 1.0000 80 chr8:10653575-10653655 1.0000 80 chr12:32201010-32201090 1.0000 80 chr4:154449959-154450039 1.0000 80 chr10:7049691-7049771 1.0000 80 chr5:111885592-111885672 1.0000 80 chr10:134956864-13495694 1.0000 80 chr13:95923475-95923555 1.0000 80 chr8:23366396-23366476 1.0000 80 chr11:62645235-62645315 1.0000 80 chr9:4862952-4863032 1.0000 80 chr16:21272963-21273043 1.0000 80 chr1:27118210-27118290 1.0000 80 chr21:40357698-40357778 1.0000 80 chr2:172487781-172487861 1.0000 80 chr2:58916112-58916192 1.0000 80 chr12:65114778-65114858 1.0000 80 chrX:55041553-55041633 1.0000 80 chr8:109455800-109455880 1.0000 80 chr11:62136580-62136660 1.0000 80 chr7:100271058-100271138 1.0000 80 chr8:2645853-2645933 1.0000 80 chr3:57584941-57585021 1.0000 80 chr12:48171655-48171735 1.0000 80 chr16:21548245-21548325 1.0000 80 chr4:145061883-145061963 1.0000 80 chr7:99659278-99659358 1.0000 80 chr17:47841775-47841855 1.0000 80 chr11:5618011-5618091 1.0000 80 chr1:180182659-180182739 1.0000 80 chr18:75034037-75034117 1.0000 80 chr11:876103-876183 1.0000 80 chr11:61109835-61109915 1.0000 80 chr8:54755814-54755894 1.0000 80 chr6:142337964-142338044 1.0000 80 chr5:150845260-150845340 1.0000 80 chr18:43733358-43733438 1.0000 80 chr1:243269315-243269395 1.0000 80 chr7:4815190-4815270 1.0000 80 chr7:39849956-39850036 1.0000 80 chr16:25783248-25783328 1.0000 80 chr6:37369593-37369673 1.0000 80 chr11:85780158-85780238 1.0000 80 chr18:67693009-67693089 1.0000 80 chr1:202036418-202036498 1.0000 80 chr15:72668338-72668418 1.0000 80 chr8:49379278-49379358 1.0000 80 chr11:6271222-6271302 1.0000 80 chr6:10725446-10725526 1.0000 80 chr5:178110920-178111000 1.0000 80 chr20:37192600-37192680 1.0000 80 chr10:43142673-43142753 1.0000 80 chr3:152949161-152949241 1.0000 80 chr5:149879215-149879295 1.0000 80 chr2:174939672-174939752 1.0000 80 chr8:93107691-93107771 1.0000 80 chr9:132875221-132875301 1.0000 80 chr11:67159292-67159372 1.0000 80 chr13:19398952-19399032 1.0000 80 chr2:128300681-128300761 1.0000 80 chr17:19913665-19913745 1.0000 80 chr15:88214710-88214790 1.0000 80 chr14:103844542-10384462 1.0000 80 chrX:102356743-102356823 1.0000 80 chr19:14502094-14502174 1.0000 80 chr12:56109776-56109856 1.0000 80 chr8:73046751-73046831 1.0000 80 chr15:75628333-75628413 1.0000 80 chr15:69284224-69284304 1.0000 80 chr3:49398944-49399024 1.0000 80 chr10:126406635-12640671 1.0000 80 chr12:53703919-53703999 1.0000 80 chr7:157195949-157196029 1.0000 80 chr3:101249328-101249408 1.0000 80 chr22:36764689-36764769 1.0000 80 chr12:28345243-28345323 1.0000 80 chr2:178504421-178504501 1.0000 80 chr13:39573074-39573154 1.0000 80 chr4:140364982-140365062 1.0000 80 chr1:35309375-35309455 1.0000 80 chr7:72176134-72176214 1.0000 80 chr4:145000048-145000128 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_CBFA2T2/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/CBFA2T2.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.236 C 0.252 G 0.272 T 0.24 Background letter frequencies (from file dataset with add-one prior applied): A 0.236 C 0.252 G 0.272 T 0.24 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TCACGTGA MEME-1 width = 8 sites = 44 llr = 449 E-value = 5.9e-048 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::a::::a pos.-specific C :a:9:::: probability G ::::a:a: matrix T a::1:a:: bits 2.1 * * 1.9 *** *** 1.7 *** **** 1.5 *** **** Relative 1.2 ******** Entropy 1.0 ******** (14.7 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCACGTGA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr15:75628333-75628413 25 1.51e-05 TTAGTCCAAG TCACGTGA TCGTCGACTC chr12:56109776-56109856 35 1.51e-05 GTTCCCAACC TCACGTGA CACAGCGGTC chr11:67159292-67159372 22 1.51e-05 GCCTCCCCGG TCACGTGA CACCCCGGAC chr15:72668338-72668418 60 1.51e-05 TATCGGCGAA TCACGTGA CCAGAGGCGG chr11:85780158-85780238 10 1.51e-05 TGCCCCGGG TCACGTGA CTCGGACACC chr7:4815190-4815270 58 1.51e-05 GCCGCTGCGC TCACGTGA CGCGGTCCCG chr8:54755814-54755894 31 1.51e-05 GAGGCGCCGG TCACGTGA TCGGAGGCAC chr1:180182659-180182739 49 1.51e-05 GGAGTCAGGG TCACGTGA CTAATTCTAG chr17:47841775-47841855 49 1.51e-05 AAATATAATG TCACGTGA CGTCAGGCTG chr7:100271058-100271138 45 1.51e-05 GGGAGGCTGA TCACGTGA CCAGCGAGCG chr8:109455800-109455880 33 1.51e-05 CGGTGGCGGG TCACGTGA CTGCGTCTCC chr19:41256412-41256492 51 1.51e-05 CATTTTGCGA TCACGTGA CAGAAAACGC chr12:120755546-12075562 49 1.51e-05 GCACACAGCA TCACGTGA CACGAAAAGG chr9:117349941-117350021 49 1.51e-05 CGCTGTGCGG TCACGTGA CAACGGGGGC chr19:7587441-7587521 27 1.51e-05 CCAGAGGCGG TCACGTGA GGGGCTCTGG chr10:75690637-75690717 51 1.51e-05 gtgaagcaag tcacgtga ttacaagata chr5:150827102-150827182 53 1.51e-05 GGCGGTGGGA TCACGTGA TGAGGTCCGG chr1:11866206-11866286 44 1.51e-05 CCGGGGCCAG TCACGTGA GGCGCAGATC chr22:31365122-31365202 51 1.51e-05 CCCGCCCCTG TCACGTGA CAGCGTGCGC chr1:110881786-110881866 31 1.51e-05 ACACTTTGGG TCACGTGA CCGCAGAGTG chr16:28503368-28503448 22 1.51e-05 GTTTGTCGGA TCACGTGA CAGCACCCGC chr19:12833507-12833587 46 1.51e-05 CAAGGTCCGG TCACGTGA CCAAAGAGTT chr17:46625711-46625791 50 1.51e-05 GGGCTTCGGG TCACGTGA CACCTTCTTT chr10:46222589-46222669 65 1.51e-05 TGACATCAGG TCACGTGA GGCCGGTC chr12:65153196-65153276 10 1.51e-05 TAGGCGCGA TCACGTGA GCCAGGGACA chr16:57220078-57220158 47 1.51e-05 GTCCCGCTGA TCACGTGA CACGATTTTT chr19:49457982-49458062 11 1.51e-05 CATTGGACAG TCACGTGA CGGGACCAAA chr17:6915640-6915720 23 1.51e-05 TAGTTCCTCG TCACGTGA CGTGACAGGC chr19:40854416-40854496 5 1.51e-05 ACCA TCACGTGA CCGCCCACCG chr14:20923291-20923371 49 1.51e-05 GCGCCTCTGA TCACGTGA CCAGGTCCGC chr10:70883886-70883966 52 1.51e-05 CGGCCCGAGG TCACGTGA CGGAGCGCCG chr13:49684356-49684436 38 1.51e-05 GTGATGACTG TCACGTGA CTCGGTCAAA chr19:3990351-3990431 43 1.51e-05 tcagaatgtg tcacgtga ccatactcag chr17:7137857-7137937 44 1.51e-05 CCGCCCTCCG TCACGTGA TCCCCTCCCA chr4:10497402-10497482 35 1.51e-05 gaggagaagg tcacgtga ccatagagag chr1:155211032-155211112 29 2.94e-05 TGTGGATGGG TCATGTGA TGACTAGGAG chr21:45937290-45937370 17 2.94e-05 ACAAGCTGGG TCATGTGA CTGGCACTAG chr1:155188793-155188873 30 2.94e-05 TGTGGATGGG TCATGTGA TGACTAGGAG chr9:132875221-132875301 40 4.35e-05 actcctgagc tcaagtga tccacccacc chr7:916018-916098 23 7.51e-05 CGCCCCTGGG TCACGTGT TGCCTGCGGA chr2:239331054-239331134 49 7.51e-05 GCAGCTGCAG TCAGGTGA GGAGATAAAT chr12:58146255-58146335 28 1.07e-04 GCGATGGCAG CCACGTGA TCTGTTGCTA chr15:93160909-93160989 25 1.07e-04 GTGGCCAGGC TCCCGTGA GTCACCACTC chr11:126081591-12608167 24 1.24e-04 GCCCTGCAGG TCACGTGG TGCGGGGTGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr15:75628333-75628413 1.5e-05 24_[+1]_48 chr12:56109776-56109856 1.5e-05 34_[+1]_38 chr11:67159292-67159372 1.5e-05 21_[+1]_51 chr15:72668338-72668418 1.5e-05 59_[+1]_13 chr11:85780158-85780238 1.5e-05 9_[+1]_63 chr7:4815190-4815270 1.5e-05 57_[+1]_15 chr8:54755814-54755894 1.5e-05 30_[+1]_42 chr1:180182659-180182739 1.5e-05 48_[+1]_24 chr17:47841775-47841855 1.5e-05 48_[+1]_24 chr7:100271058-100271138 1.5e-05 44_[+1]_28 chr8:109455800-109455880 1.5e-05 32_[+1]_40 chr19:41256412-41256492 1.5e-05 50_[+1]_22 chr12:120755546-12075562 1.5e-05 48_[+1]_24 chr9:117349941-117350021 1.5e-05 48_[+1]_24 chr19:7587441-7587521 1.5e-05 26_[+1]_46 chr10:75690637-75690717 1.5e-05 50_[+1]_22 chr5:150827102-150827182 1.5e-05 52_[+1]_20 chr1:11866206-11866286 1.5e-05 43_[+1]_29 chr22:31365122-31365202 1.5e-05 50_[+1]_22 chr1:110881786-110881866 1.5e-05 30_[+1]_42 chr16:28503368-28503448 1.5e-05 21_[+1]_51 chr19:12833507-12833587 1.5e-05 45_[+1]_27 chr17:46625711-46625791 1.5e-05 49_[+1]_23 chr10:46222589-46222669 1.5e-05 64_[+1]_8 chr12:65153196-65153276 1.5e-05 9_[+1]_63 chr16:57220078-57220158 1.5e-05 46_[+1]_26 chr19:49457982-49458062 1.5e-05 10_[+1]_62 chr17:6915640-6915720 1.5e-05 22_[+1]_50 chr19:40854416-40854496 1.5e-05 4_[+1]_68 chr14:20923291-20923371 1.5e-05 48_[+1]_24 chr10:70883886-70883966 1.5e-05 51_[+1]_21 chr13:49684356-49684436 1.5e-05 37_[+1]_35 chr19:3990351-3990431 1.5e-05 42_[+1]_30 chr17:7137857-7137937 1.5e-05 43_[+1]_29 chr4:10497402-10497482 1.5e-05 34_[+1]_38 chr1:155211032-155211112 2.9e-05 28_[+1]_44 chr21:45937290-45937370 2.9e-05 16_[+1]_56 chr1:155188793-155188873 2.9e-05 29_[+1]_43 chr9:132875221-132875301 4.4e-05 39_[+1]_33 chr7:916018-916098 7.5e-05 22_[+1]_50 chr2:239331054-239331134 7.5e-05 48_[+1]_24 chr12:58146255-58146335 0.00011 27_[+1]_45 chr15:93160909-93160989 0.00011 24_[+1]_48 chr11:126081591-12608167 0.00012 23_[+1]_49 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCACGTGA width=8 seqs=44 chr15:75628333-75628413 ( 25) TCACGTGA 1 chr12:56109776-56109856 ( 35) TCACGTGA 1 chr11:67159292-67159372 ( 22) TCACGTGA 1 chr15:72668338-72668418 ( 60) TCACGTGA 1 chr11:85780158-85780238 ( 10) TCACGTGA 1 chr7:4815190-4815270 ( 58) TCACGTGA 1 chr8:54755814-54755894 ( 31) TCACGTGA 1 chr1:180182659-180182739 ( 49) TCACGTGA 1 chr17:47841775-47841855 ( 49) TCACGTGA 1 chr7:100271058-100271138 ( 45) TCACGTGA 1 chr8:109455800-109455880 ( 33) TCACGTGA 1 chr19:41256412-41256492 ( 51) TCACGTGA 1 chr12:120755546-12075562 ( 49) TCACGTGA 1 chr9:117349941-117350021 ( 49) TCACGTGA 1 chr19:7587441-7587521 ( 27) TCACGTGA 1 chr10:75690637-75690717 ( 51) TCACGTGA 1 chr5:150827102-150827182 ( 53) TCACGTGA 1 chr1:11866206-11866286 ( 44) TCACGTGA 1 chr22:31365122-31365202 ( 51) TCACGTGA 1 chr1:110881786-110881866 ( 31) TCACGTGA 1 chr16:28503368-28503448 ( 22) TCACGTGA 1 chr19:12833507-12833587 ( 46) TCACGTGA 1 chr17:46625711-46625791 ( 50) TCACGTGA 1 chr10:46222589-46222669 ( 65) TCACGTGA 1 chr12:65153196-65153276 ( 10) TCACGTGA 1 chr16:57220078-57220158 ( 47) TCACGTGA 1 chr19:49457982-49458062 ( 11) TCACGTGA 1 chr17:6915640-6915720 ( 23) TCACGTGA 1 chr19:40854416-40854496 ( 5) TCACGTGA 1 chr14:20923291-20923371 ( 49) TCACGTGA 1 chr10:70883886-70883966 ( 52) TCACGTGA 1 chr13:49684356-49684436 ( 38) TCACGTGA 1 chr19:3990351-3990431 ( 43) TCACGTGA 1 chr17:7137857-7137937 ( 44) TCACGTGA 1 chr4:10497402-10497482 ( 35) TCACGTGA 1 chr1:155211032-155211112 ( 29) TCATGTGA 1 chr21:45937290-45937370 ( 17) TCATGTGA 1 chr1:155188793-155188873 ( 30) TCATGTGA 1 chr9:132875221-132875301 ( 40) TCAAGTGA 1 chr7:916018-916098 ( 23) TCACGTGT 1 chr2:239331054-239331134 ( 49) TCAGGTGA 1 chr12:58146255-58146335 ( 28) CCACGTGA 1 chr15:93160909-93160989 ( 25) TCCCGTGA 1 chr11:126081591-12608167 ( 24) TCACGTGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.72094 E= 5.9e-048 -1210 -347 -1210 203 -1210 199 -1210 -1210 205 -347 -1210 -1210 -338 181 -358 -181 -1210 -1210 188 -1210 -1210 -1210 -1210 206 -1210 -1210 188 -1210 201 -1210 -358 -339 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 44 E= 5.9e-048 0.000000 0.022727 0.000000 0.977273 0.000000 1.000000 0.000000 0.000000 0.977273 0.022727 0.000000 0.000000 0.022727 0.886364 0.022727 0.068182 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.954545 0.000000 0.022727 0.022727 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 regular expression -------------------------------------------------------------------------------- TCACGTGA -------------------------------------------------------------------------------- Time 4.84 secs. ******************************************************************************** ******************************************************************************** MOTIF AGATAAGV MEME-2 width = 8 sites = 95 llr = 710 E-value = 8.5e-041 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGATAAGV MEME-2 Description -------------------------------------------------------------------------------- Simplified A 8:a:9724 pos.-specific C ::::::22 probability G :a::1364 matrix T 2::a:::1 bits 2.1 ** 1.9 *** 1.7 **** 1.5 **** Relative 1.2 ****** Entropy 1.0 ****** (10.8 bits) 0.8 ****** 0.6 ******* 0.4 ******* 0.2 ******** 0.0 -------- Multilevel AGATAAGA consensus T GAG sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGV MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:152949161-152949241 32 1.30e-05 tggggcacag agataaga ggttggggca chr5:178110920-178111000 6 1.30e-05 gcctt agataaga gagtgaatgg chr8:49379278-49379358 68 1.30e-05 gcacttaacc agataaga catga chr2:172487781-172487861 36 1.30e-05 ggaggacatg agataaga ttgtgcaggc chr6:16263874-16263954 16 1.30e-05 tggggtgcag agataaga ggtcagggca chr1:35602536-35602616 37 1.30e-05 tggggcaaag agataaga ggttggggca chrX:114557050-114557130 59 1.30e-05 acagctgcac agataaga aaggctacac chr9:102907625-102907705 7 1.30e-05 gcgcag agataaga ggttggggcg chr9:125209230-125209310 62 1.30e-05 ggtaaaacac agataaga cagcttgggc chr9:69491640-69491720 29 1.30e-05 tttgcagttg agataaga ggaaggcatc chr14:88491088-88491168 69 1.30e-05 tttgcagttg agataaga ggaa chr8:73046751-73046831 44 2.80e-05 tgtggcgcct agataagg gttcaagaat chrX:102356743-102356823 15 2.80e-05 gggtacacta agataagg aagctaaaag chr13:19398952-19399032 40 2.80e-05 agttaagtgc agataagg gaacctggac chr16:21548245-21548325 41 2.80e-05 GCTTTCCCCG AGATAAGG CCATGAGGCC chr17:26854456-26854536 30 2.80e-05 CAGGATAGGC AGATAAGG ACAGCAGGGC chr15:31270664-31270744 47 2.80e-05 GCTGGCTGGA AGATAAGG GCTGTTTGGG chrX:47572300-47572380 51 2.80e-05 aggtgcacta agataagg aagctaaaag chr8:37939618-37939698 72 2.80e-05 tggtgagtac agataagg c chr7:104607707-104607787 7 2.80e-05 CTGAGT AGATAAGG CAAGCTGGGA chr13:44956980-44957060 9 2.80e-05 ggagaggc agataagg aagctgtcag chr14:23366707-23366787 23 2.80e-05 AGCTGCTTCA AGATAAGG TCTGAGGCTG chr5:149879215-149879295 45 4.19e-05 TCCTCCCCCA AGATAAGC TCTGCCTGCG chr11:876103-876183 62 4.19e-05 GTGCAAGGAC AGATAAGC CTCGAGAAAG chr16:10437114-10437194 46 4.19e-05 gaaggtccca agataagc ctgagcaaac chr2:58916112-58916192 26 5.31e-05 agggccttat agataaaa ctcctatctc chr22:35608152-35608232 26 5.31e-05 CACCTAACAA AGATAAAA TGTCCTCAGC chr17:19913665-19913745 5 6.61e-05 CAGC AGATAAAG TGTTTTTTGA chr11:6271222-6271302 53 6.61e-05 CTGCCAGCAA AGATAAAG GACTACCAGC chr6:159303111-159303191 68 6.61e-05 tgggttctgg agataaag agtaa chr15:93160909-93160989 69 6.61e-05 TGGAGAGGAG AGATAAAG CAGC chr17:14064895-14064975 71 6.61e-05 ggaagagaac agataaag aa chr10:63540225-63540305 49 6.61e-05 GGCCTCCACT AGATAAAG ACATCTGGAT chrX:55054625-55054705 8 6.61e-05 AGACCAC AGATAAAG TTGCCAGAGT chr16:25783248-25783328 32 8.11e-05 ATTTAGTGGA AGATAGGA TAACGTTTCT chr5:150845260-150845340 58 8.11e-05 CGCACATGAG AGATAGGA GCAAAGAAGG chr8:2645853-2645933 42 8.11e-05 ccagctctgg agatagga agacaggttc chrX:55041553-55041633 73 8.11e-05 TGCTGCTTTG AGATAGGA chr7:72176134-72176214 15 1.10e-04 aggtgcacta agataggg aggctaaaag chr22:36764689-36764769 8 1.10e-04 TTCTCTA AGATAACA GTGCTGGGAG chr7:39849956-39850036 30 1.10e-04 CACATGGGCC AGATAACA CAGCACAGCT chr4:154449959-154450039 17 1.10e-04 TGTGGGCCAC AGATAGGG TAGACTTTGA chr1:70005908-70005988 36 1.10e-04 GTGAGGACTA AGATAGGG TCGAGTTATC chr10:75690637-75690717 64 1.10e-04 cgtgattaca agataggg ggcccttcc chrX:47535553-47535633 34 1.10e-04 aggtgcacta agataggg aagctaaaag chr11:62645235-62645315 52 1.38e-04 aggtggtggc tgataaga ttggagaggc chr1:25739903-25739983 68 1.38e-04 TGTTCAGGGG TGATAAGA AGTGG chr1:109677202-109677282 17 1.38e-04 GTTGGCCTAC TGATAAGA AACCGTGGCT chr1:207020987-207021067 52 1.38e-04 cttgtcaccc tgataaga atgacacagg chr15:39432301-39432381 17 1.38e-04 CGCCCTGCAG TGATAAGA GCACAGCTGT chr4:140364982-140365062 13 1.78e-04 ttgtcggagg agataaac cctacactgc chr9:4862952-4863032 55 1.78e-04 TTTTTTAGGC AGATAAAC CTGTGAACTT chr12:32201010-32201090 21 1.78e-04 tttacacaac agataagt ggctttaaaa chr4:25052516-25052596 25 1.78e-04 TGTTAGGGTC AGATAAGT CCTGGTTAGG chr5:32288427-32288507 28 1.78e-04 cctttgtctg agataaac tctgcactgc chr6:10725446-10725526 55 1.94e-04 CTTTATCTAC AGATAGGC AGGGGCGGTT chr2:239331054-239331134 20 1.94e-04 CTGCCAGGAG AGATAGGC CAGCTCCTCC chr12:48171655-48171735 7 2.20e-04 tgccag agataacc actttcccca chr5:29796334-29796414 46 2.20e-04 AGTTGAATAA AGATAACC TGGACCACCA chr3:6582811-6582891 64 2.20e-04 tgccctctcc agatagaa gggaatcta chr21:40357698-40357778 68 2.49e-04 GGGTGTTCAC AGATAGAG CTGGA chr1:228366648-228366728 24 2.49e-04 tgctctggcc agatagag gtgggctctg chr14:35122459-35122539 50 2.49e-04 tttgcattac tgataagc cctctatcat chr19:381064-381144 71 2.49e-04 CCGTGGTGAT TGATAAGC AG chr11:61109835-61109915 33 2.60e-04 TGTGAGTCCT TGATAAAA ACGATGAGCA chr1:65487632-65487712 57 2.85e-04 CGTTAGACTG TGATAAAG GTGACTCAAG chr17:72329122-72329202 40 2.85e-04 CTGTTGGGAA AGATAAAT AAAGTATAAG chr3:142337821-142337901 33 3.45e-04 TTGACAAATA AGATAGCG GTGGTTATCG chr12:65114778-65114858 44 4.21e-04 CCAGATGGTC AGATGAGG GTTGCCAGAT chr13:95923475-95923555 62 4.21e-04 GTGTGCAATG TGATAGGG GCTGGCTGGG chr13:44961220-44961300 73 4.21e-04 ACTGTCACAC AGATAGGT chr3:125152082-125152162 14 4.21e-04 tgtgcagtgc tgataaca ccaacgttgc chr4:1884770-1884850 51 4.21e-04 ggataaggag agatgagg ggaagttctg chr8:98790773-98790853 67 4.21e-04 tgtgtccggt tgataaca cccaaa chr4:10497402-10497482 57 4.21e-04 agagagagag agatgagg agaaggtcac chr8:10653575-10653655 34 4.48e-04 TCAGTTCAAA TGATAACG GGATGGGAGA chr6:80314382-80314462 41 4.48e-04 tgttgggggc agataact tgtcttttta chr8:144016038-144016118 4 4.48e-04 AAT TGATAACG AACTGAGCGT chr18:43733358-43733438 62 4.88e-04 TGATGCAGGG AGATAGCC TCCTAACTGC chr4:145061883-145061963 35 5.21e-04 CATCATCAGC TGATAGGC AGGGGAGGCA chr4:144826776-144826856 14 5.21e-04 CATCATCAGC TGATAGGC AGGGGAGGCA chr4:144940569-144940649 1 5.21e-04 . TGATAGGC AGGGGAGGCA chr1:224058442-224058522 62 5.21e-04 tgtcccaggg agatgagc attttatctg chr19:14502094-14502174 15 5.60e-04 ggccaaatcc tgataacc aagtgtatga chr14:24725550-24725630 38 5.60e-04 CCAGCCTGCC TGATAACC AAGTCCCTGA chr8:38068316-38068396 32 5.60e-04 GAAACCTACC AGATGAAA CTGGATATAA chr13:39573074-39573154 5 6.03e-04 ggca tgatagag agcctgcctt chr11:34258304-34258384 34 6.03e-04 GCTCGCTCCT AGATAGAT TAGCACCTTC chr4:145000048-145000128 40 6.32e-04 gatactctcc agatggga gagagtttcc chr3:32115895-32115975 58 6.32e-04 attaccaaac agatggga gcattccaac chr3:129512923-129513003 18 6.80e-04 GCCCAAATTC AGATGACA GCTGCAGTTT chr1:202036418-202036498 2 7.42e-04 c agatagct cccagctgtc chr12:125369563-12536964 53 8.30e-04 tgggtgggcc tgataact gcattttcag chr1:180182659-180182739 73 8.94e-04 CTAGCCAATG AGATGGAA chr6:164767856-164767936 51 8.94e-04 TGGATAAGAC AGATGGAA GGTTGCTTAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGV MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:152949161-152949241 1.3e-05 31_[+2]_41 chr5:178110920-178111000 1.3e-05 5_[+2]_67 chr8:49379278-49379358 1.3e-05 67_[+2]_5 chr2:172487781-172487861 1.3e-05 35_[+2]_37 chr6:16263874-16263954 1.3e-05 15_[+2]_57 chr1:35602536-35602616 1.3e-05 36_[+2]_36 chrX:114557050-114557130 1.3e-05 58_[+2]_14 chr9:102907625-102907705 1.3e-05 6_[+2]_66 chr9:125209230-125209310 1.3e-05 61_[+2]_11 chr9:69491640-69491720 1.3e-05 28_[+2]_44 chr14:88491088-88491168 1.3e-05 68_[+2]_4 chr8:73046751-73046831 2.8e-05 43_[+2]_29 chrX:102356743-102356823 2.8e-05 14_[+2]_58 chr13:19398952-19399032 2.8e-05 39_[+2]_33 chr16:21548245-21548325 2.8e-05 40_[+2]_32 chr17:26854456-26854536 2.8e-05 29_[+2]_43 chr15:31270664-31270744 2.8e-05 46_[+2]_26 chrX:47572300-47572380 2.8e-05 50_[+2]_22 chr8:37939618-37939698 2.8e-05 71_[+2]_1 chr7:104607707-104607787 2.8e-05 6_[+2]_66 chr13:44956980-44957060 2.8e-05 8_[+2]_64 chr14:23366707-23366787 2.8e-05 22_[+2]_50 chr5:149879215-149879295 4.2e-05 44_[+2]_28 chr11:876103-876183 4.2e-05 61_[+2]_11 chr16:10437114-10437194 4.2e-05 45_[+2]_27 chr2:58916112-58916192 5.3e-05 25_[+2]_47 chr22:35608152-35608232 5.3e-05 25_[+2]_47 chr17:19913665-19913745 6.6e-05 4_[+2]_68 chr11:6271222-6271302 6.6e-05 52_[+2]_20 chr6:159303111-159303191 6.6e-05 67_[+2]_5 chr15:93160909-93160989 6.6e-05 68_[+2]_4 chr17:14064895-14064975 6.6e-05 70_[+2]_2 chr10:63540225-63540305 6.6e-05 48_[+2]_24 chrX:55054625-55054705 6.6e-05 7_[+2]_65 chr16:25783248-25783328 8.1e-05 31_[+2]_41 chr5:150845260-150845340 8.1e-05 57_[+2]_15 chr8:2645853-2645933 8.1e-05 41_[+2]_31 chrX:55041553-55041633 8.1e-05 72_[+2] chr7:72176134-72176214 0.00011 14_[+2]_58 chr22:36764689-36764769 0.00011 7_[+2]_65 chr7:39849956-39850036 0.00011 29_[+2]_43 chr4:154449959-154450039 0.00011 16_[+2]_56 chr1:70005908-70005988 0.00011 35_[+2]_37 chr10:75690637-75690717 0.00011 63_[+2]_9 chrX:47535553-47535633 0.00011 33_[+2]_39 chr11:62645235-62645315 0.00014 51_[+2]_21 chr1:25739903-25739983 0.00014 67_[+2]_5 chr1:109677202-109677282 0.00014 16_[+2]_56 chr1:207020987-207021067 0.00014 51_[+2]_21 chr15:39432301-39432381 0.00014 16_[+2]_56 chr4:140364982-140365062 0.00018 12_[+2]_60 chr9:4862952-4863032 0.00018 54_[+2]_18 chr12:32201010-32201090 0.00018 20_[+2]_52 chr4:25052516-25052596 0.00018 24_[+2]_48 chr5:32288427-32288507 0.00018 27_[+2]_45 chr6:10725446-10725526 0.00019 54_[+2]_18 chr2:239331054-239331134 0.00019 19_[+2]_53 chr12:48171655-48171735 0.00022 6_[+2]_66 chr5:29796334-29796414 0.00022 45_[+2]_27 chr3:6582811-6582891 0.00022 63_[+2]_9 chr21:40357698-40357778 0.00025 67_[+2]_5 chr1:228366648-228366728 0.00025 23_[+2]_49 chr14:35122459-35122539 0.00025 49_[+2]_23 chr19:381064-381144 0.00025 70_[+2]_2 chr11:61109835-61109915 0.00026 32_[+2]_40 chr1:65487632-65487712 0.00029 56_[+2]_16 chr17:72329122-72329202 0.00029 39_[+2]_33 chr3:142337821-142337901 0.00035 32_[+2]_40 chr12:65114778-65114858 0.00042 43_[+2]_29 chr13:95923475-95923555 0.00042 61_[+2]_11 chr13:44961220-44961300 0.00042 72_[+2] chr3:125152082-125152162 0.00042 13_[+2]_59 chr4:1884770-1884850 0.00042 50_[+2]_22 chr8:98790773-98790853 0.00042 66_[+2]_6 chr4:10497402-10497482 0.00042 56_[+2]_16 chr8:10653575-10653655 0.00045 33_[+2]_39 chr6:80314382-80314462 0.00045 40_[+2]_32 chr8:144016038-144016118 0.00045 3_[+2]_69 chr18:43733358-43733438 0.00049 61_[+2]_11 chr4:145061883-145061963 0.00052 34_[+2]_38 chr4:144826776-144826856 0.00052 13_[+2]_59 chr4:144940569-144940649 0.00052 [+2]_72 chr1:224058442-224058522 0.00052 61_[+2]_11 chr19:14502094-14502174 0.00056 14_[+2]_58 chr14:24725550-24725630 0.00056 37_[+2]_35 chr8:38068316-38068396 0.00056 31_[+2]_41 chr13:39573074-39573154 0.0006 4_[+2]_68 chr11:34258304-34258384 0.0006 33_[+2]_39 chr4:145000048-145000128 0.00063 39_[+2]_33 chr3:32115895-32115975 0.00063 57_[+2]_15 chr3:129512923-129513003 0.00068 17_[+2]_55 chr1:202036418-202036498 0.00074 1_[+2]_71 chr12:125369563-12536964 0.00083 52_[+2]_20 chr1:180182659-180182739 0.00089 72_[+2] chr6:164767856-164767936 0.00089 50_[+2]_22 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGV MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGATAAGV width=8 seqs=95 chr3:152949161-152949241 ( 32) AGATAAGA 1 chr5:178110920-178111000 ( 6) AGATAAGA 1 chr8:49379278-49379358 ( 68) AGATAAGA 1 chr2:172487781-172487861 ( 36) AGATAAGA 1 chr6:16263874-16263954 ( 16) AGATAAGA 1 chr1:35602536-35602616 ( 37) AGATAAGA 1 chrX:114557050-114557130 ( 59) AGATAAGA 1 chr9:102907625-102907705 ( 7) AGATAAGA 1 chr9:125209230-125209310 ( 62) AGATAAGA 1 chr9:69491640-69491720 ( 29) AGATAAGA 1 chr14:88491088-88491168 ( 69) AGATAAGA 1 chr8:73046751-73046831 ( 44) AGATAAGG 1 chrX:102356743-102356823 ( 15) AGATAAGG 1 chr13:19398952-19399032 ( 40) AGATAAGG 1 chr16:21548245-21548325 ( 41) AGATAAGG 1 chr17:26854456-26854536 ( 30) AGATAAGG 1 chr15:31270664-31270744 ( 47) AGATAAGG 1 chrX:47572300-47572380 ( 51) AGATAAGG 1 chr8:37939618-37939698 ( 72) AGATAAGG 1 chr7:104607707-104607787 ( 7) AGATAAGG 1 chr13:44956980-44957060 ( 9) AGATAAGG 1 chr14:23366707-23366787 ( 23) AGATAAGG 1 chr5:149879215-149879295 ( 45) AGATAAGC 1 chr11:876103-876183 ( 62) AGATAAGC 1 chr16:10437114-10437194 ( 46) AGATAAGC 1 chr2:58916112-58916192 ( 26) AGATAAAA 1 chr22:35608152-35608232 ( 26) AGATAAAA 1 chr17:19913665-19913745 ( 5) AGATAAAG 1 chr11:6271222-6271302 ( 53) AGATAAAG 1 chr6:159303111-159303191 ( 68) AGATAAAG 1 chr15:93160909-93160989 ( 69) AGATAAAG 1 chr17:14064895-14064975 ( 71) AGATAAAG 1 chr10:63540225-63540305 ( 49) AGATAAAG 1 chrX:55054625-55054705 ( 8) AGATAAAG 1 chr16:25783248-25783328 ( 32) AGATAGGA 1 chr5:150845260-150845340 ( 58) AGATAGGA 1 chr8:2645853-2645933 ( 42) AGATAGGA 1 chrX:55041553-55041633 ( 73) AGATAGGA 1 chr7:72176134-72176214 ( 15) AGATAGGG 1 chr22:36764689-36764769 ( 8) AGATAACA 1 chr7:39849956-39850036 ( 30) AGATAACA 1 chr4:154449959-154450039 ( 17) AGATAGGG 1 chr1:70005908-70005988 ( 36) AGATAGGG 1 chr10:75690637-75690717 ( 64) AGATAGGG 1 chrX:47535553-47535633 ( 34) AGATAGGG 1 chr11:62645235-62645315 ( 52) TGATAAGA 1 chr1:25739903-25739983 ( 68) TGATAAGA 1 chr1:109677202-109677282 ( 17) TGATAAGA 1 chr1:207020987-207021067 ( 52) TGATAAGA 1 chr15:39432301-39432381 ( 17) TGATAAGA 1 chr4:140364982-140365062 ( 13) AGATAAAC 1 chr9:4862952-4863032 ( 55) AGATAAAC 1 chr12:32201010-32201090 ( 21) AGATAAGT 1 chr4:25052516-25052596 ( 25) AGATAAGT 1 chr5:32288427-32288507 ( 28) AGATAAAC 1 chr6:10725446-10725526 ( 55) AGATAGGC 1 chr2:239331054-239331134 ( 20) AGATAGGC 1 chr12:48171655-48171735 ( 7) AGATAACC 1 chr5:29796334-29796414 ( 46) AGATAACC 1 chr3:6582811-6582891 ( 64) AGATAGAA 1 chr21:40357698-40357778 ( 68) AGATAGAG 1 chr1:228366648-228366728 ( 24) AGATAGAG 1 chr14:35122459-35122539 ( 50) TGATAAGC 1 chr19:381064-381144 ( 71) TGATAAGC 1 chr11:61109835-61109915 ( 33) TGATAAAA 1 chr1:65487632-65487712 ( 57) TGATAAAG 1 chr17:72329122-72329202 ( 40) AGATAAAT 1 chr3:142337821-142337901 ( 33) AGATAGCG 1 chr12:65114778-65114858 ( 44) AGATGAGG 1 chr13:95923475-95923555 ( 62) TGATAGGG 1 chr13:44961220-44961300 ( 73) AGATAGGT 1 chr3:125152082-125152162 ( 14) TGATAACA 1 chr4:1884770-1884850 ( 51) AGATGAGG 1 chr8:98790773-98790853 ( 67) TGATAACA 1 chr4:10497402-10497482 ( 57) AGATGAGG 1 chr8:10653575-10653655 ( 34) TGATAACG 1 chr6:80314382-80314462 ( 41) AGATAACT 1 chr8:144016038-144016118 ( 4) TGATAACG 1 chr18:43733358-43733438 ( 62) AGATAGCC 1 chr4:145061883-145061963 ( 35) TGATAGGC 1 chr4:144826776-144826856 ( 14) TGATAGGC 1 chr4:144940569-144940649 ( 1) TGATAGGC 1 chr1:224058442-224058522 ( 62) AGATGAGC 1 chr19:14502094-14502174 ( 15) TGATAACC 1 chr14:24725550-24725630 ( 38) TGATAACC 1 chr8:38068316-38068396 ( 32) AGATGAAA 1 chr13:39573074-39573154 ( 5) TGATAGAG 1 chr11:34258304-34258384 ( 34) AGATAGAT 1 chr4:145000048-145000128 ( 40) AGATGGGA 1 chr3:32115895-32115975 ( 58) AGATGGGA 1 chr3:129512923-129513003 ( 18) AGATGACA 1 chr1:202036418-202036498 ( 2) AGATAGCT 1 chr12:125369563-12536964 ( 53) TGATAACT 1 chr1:180182659-180182739 ( 73) AGATGGAA 1 chr6:164767856-164767936 ( 51) AGATGGAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGV MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.48684 E= 8.5e-041 172 -1321 -1321 -12 -1321 -1321 188 -1321 208 -1321 -1321 -1321 -1321 -1321 -1321 206 192 -1321 -137 -1321 158 -1321 12 -1321 3 -58 112 -1321 60 -34 40 -151 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGV MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 95 E= 8.5e-041 0.778947 0.000000 0.000000 0.221053 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.894737 0.000000 0.105263 0.000000 0.705263 0.000000 0.294737 0.000000 0.242105 0.168421 0.589474 0.000000 0.357895 0.200000 0.357895 0.084211 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGATAAGV MEME-2 regular expression -------------------------------------------------------------------------------- [AT]GATA[AG][GA][AGC] -------------------------------------------------------------------------------- Time 8.51 secs. ******************************************************************************** ******************************************************************************** MOTIF CAGCTGYN MEME-3 width = 8 sites = 98 llr = 689 E-value = 7.3e-025 ******************************************************************************** -------------------------------------------------------------------------------- Motif CAGCTGYN MEME-3 Description -------------------------------------------------------------------------------- Simplified A :9:2:::3 pos.-specific C a::7::53 probability G ::81:a22 matrix T :12:a:32 bits 2.1 * * 1.9 * ** 1.7 ** ** 1.5 ** ** Relative 1.2 *** ** Entropy 1.0 *** ** (10.1 bits) 0.8 ****** 0.6 ****** 0.4 ******* 0.2 ******* 0.0 -------- Multilevel CAGCTGCA consensus T TC sequence GG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCTGYN MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:73046751-73046831 63 1.58e-05 ttcaagaatg cagctgca gagtattcag chrX:102356743-102356823 65 1.58e-05 ggtatgcctg cagctgca gaaagata chr18:43733358-43733438 41 1.58e-05 AAGCAGGTGT CAGCTGCA GCCTGATGCA chr7:102082187-102082267 7 1.58e-05 gagcac cagctgCA GTGGGAAGCA chr4:164108621-164108701 27 1.58e-05 caccttcttg cagctgca gttatctacc chr10:43140672-43140752 56 1.58e-05 ctccctagca cagctgca aagttacaag chr14:20645711-20645791 59 1.58e-05 tgtgaccttg cagctgca cagcaagaaa chr4:84417384-84417464 2 1.58e-05 g cagctgca ggcatatccc chr2:239331054-239331134 40 1.58e-05 GCTCCTCCGG CAGCTGCA GTCAGGTGAG chrX:114557050-114557130 50 1.58e-05 gataggccca cagctgca cagataagaa chrX:47535553-47535633 73 1.58e-05 ggtatgcctg cagctgca chr3:14162510-14162590 31 1.58e-05 catctttctg cagctgca ggcatatccc chr19:3990351-3990431 58 1.58e-05 tgaccatact cagctgca agggttggtg chr4:140364982-140365062 61 3.27e-05 tcccctgagg cagctgcc aggcaagata chr13:95923475-95923555 30 3.27e-05 AATACAGAGA CAGCTGCC GACGGATTAC chr7:77502862-77502942 18 3.27e-05 tcttgcctca cagctgcc tcaggggagg chr17:72329122-72329202 69 3.27e-05 TGACAGATGT CAGCTGCC CGAG chr7:154467934-154468014 61 3.27e-05 TCTGGAGGTC CAGCTGCC CTTCCCCATG chr10:126406635-12640671 15 6.60e-05 CCTTGGAACA CAGCTGCG AGGGCAGTGA chr8:37939618-37939698 7 6.60e-05 actttg cagctgcg ctagggaggt chr8:37949357-37949437 18 6.60e-05 tgtaactttg cagctgcg ctagggaggt chr15:93160909-93160989 5 6.60e-05 CGAA CAGCTGCG AGGTGGCCAG chr22:36764689-36764769 61 9.82e-05 TTACCCCTCC CAGCTGTC TATATCGCCC chr15:88214710-88214790 55 9.82e-05 ATCCTGAACA CAGCTGCT GCATTTATCT chr1:202036418-202036498 12 9.82e-05 agatagctcc cagctgtc agctctgtca chr1:25739903-25739983 23 9.82e-05 GCACTCACAT CAGCTGCT GGTTTGATAA chr1:151687987-151688067 34 9.82e-05 CACCCCTACC CAGCTGCT TATCTCCCAA chr14:100038917-10003899 48 9.82e-05 CCAGGGACGA CAGCTGCT TATCATCCAA chr1:35309375-35309455 30 1.33e-04 TCTCTGGCTC CAGCTGGA CTCAGGAAAG chr11:6271222-6271302 1 1.33e-04 . CAGCTGTG CCAGCGAAAG chr2:58916112-58916192 72 1.33e-04 gggggaggga cagctgtg g chr22:35608152-35608232 43 1.33e-04 ATGTCCTCAG CAGCTGGA AGGCAGCAAA chr2:17899104-17899184 4 1.33e-04 agc cagctgtg gtgacagatg chr7:104607707-104607787 68 1.33e-04 GCAAAGTAAG CAGCTGGA ATGAC chr17:31298383-31298463 62 1.33e-04 agcactgaga cagctgtg caaacagctg chr9:131355492-131355572 44 1.33e-04 CTTCCATGTG CAGCTGTG TGTTCAGAGT chr15:39432301-39432381 28 1.33e-04 GATAAGAGCA CAGCTGTG GGAAAGCCAG chr11:27223269-27223349 44 1.81e-04 CAGACACTTG CAGCTGGC TGGGAAATGA chr17:14064895-14064975 45 1.81e-04 gggtaacatc cagctggc tggaggctgg chr11:61370697-61370777 18 1.81e-04 TCCTGGAGCC CAGCTGTT GCACAGATGT chr4:154449959-154450039 48 2.15e-04 TCAAGAGAAA CATCTGCA ATGGTTTCTT chr12:108879359-10887943 44 2.15e-04 ataagacagc catctgca aaaccaagga chr12:32207214-32207294 14 2.15e-04 gggaaactca catctgca cctgccacca chr1:211395914-211395994 36 2.31e-04 gatcaggaga cagatgcc ttcctcttat chr8:49379278-49379358 51 2.94e-04 accctctggg cagatgcg cacttaacca chr19:38613549-38613629 38 2.94e-04 gcttaaccac catctgcc atgcactgtg chr4:25052516-25052596 68 2.94e-04 ACAGTAAGTC CAGATGCG GCTGT chr17:62971008-62971088 33 2.94e-04 AATATAAAAC CAGATGTA CCTTCCAGTG chr1:95100699-95100779 21 2.94e-04 GAGCGGGGAG CAGCTGGT TATCATGAAC chr19:381064-381144 38 2.94e-04 TGGTGATGAG CAGATGTA GGAGGTGGAG chr18:9848292-9848372 70 3.23e-04 tctatctatt catctgta cat chr15:75987054-75987134 61 3.23e-04 CCCTGCAGAC CATCTGCG CGGGGGCGGC chr6:37369593-37369673 3 3.54e-04 cc cagatgtc tgttatctag chr12:48171655-48171735 27 3.54e-04 tttccccaac cagatgct tatccttcct chr13:44972146-44972226 69 3.54e-04 TAGCACAGAG CAGATGTC CCAG chrX:55041553-55041633 26 4.14e-04 GGCCTCTGCT CATCTGTC CATGACAAGG chr21:40357698-40357778 33 4.14e-04 CCTCACCCAA CATCTGTC CTGCGGCGGG chr3:142337821-142337901 2 4.14e-04 a caGATGTG TTGTCTGCCT chr16:14491344-14491424 23 4.14e-04 TATCCAAGAC CATCTGCT AGAGATACAG chr14:24725550-24725630 16 4.14e-04 GGGCAGGGTA CAGATGTG CGGACCAGCC chr6:80314382-80314462 72 4.14e-04 cactggtttc cagatgga g chr9:69491640-69491720 43 4.14e-04 aagaggaagg catctgtc tcctgctgtc chr8:144016038-144016118 38 4.14e-04 AGGCTCAAGC CAGATGTG CTGCACCGTG chr7:72176134-72176214 4 4.62e-04 att caggtgca ctaagatagg chr11:876103-876183 49 4.62e-04 GGAGCCGGCA CAGGTGCA AGGACAGATA chrX:47572300-47572380 40 4.62e-04 cctttccctt caggtgca ctaagataag chr10:63540225-63540305 58 4.62e-04 TAGATAAAGA CATCTGGA TGACTGTCTG chr1:228608968-228609048 68 4.62e-04 tctactggga catctgga gccta chr17:62919223-62919303 63 4.62e-04 CCTCCTTCTG CATCTGGA GTCTAGAAGG chr8:2645853-2645933 4 4.78e-04 tca ctgctgca ggattgctga chr1:109677202-109677282 45 4.78e-04 GCTCAGGCGG CTGCTGCA CCTGCTGCTT chr15:69284224-69284304 18 5.09e-04 ctgtgcggtc cagatggc tgttatctag chr1:6489896-6489976 26 5.09e-04 ACTCAGTGGC CAGATGGC CTGGACTGAT chr2:178504421-178504501 18 5.89e-04 TCGTGGTCCA CATCTGTT ATCATCTGGC chr12:65114778-65114858 26 5.89e-04 CACAGATGGG CATCTGTT CCAGATGGTC chr12:51762652-51762732 67 5.89e-04 aatgtgctgc caggtgcc agatgc chr6:159303111-159303191 34 5.89e-04 ggaatgctcc catctgtt tggttatgtg chr14:35122459-35122539 21 5.89e-04 cattaccaaa cagatggg agcattctga chr2:172487781-172487861 9 6.59e-04 attgcagc catctggg cgccatagtg chr7:24903955-24904035 53 6.59e-04 ttattccata catctggg ttgagcctga chr16:10437114-10437194 19 6.59e-04 agattgcagc catctggg caccacagtg chr19:49457982-49458062 47 6.59e-04 GGGAGCGAGG CAGGTGCG GTCACGTGAC chr14:36733973-36734053 40 6.59e-04 atctttcatc ctgctgcc tgcgatacag chr3:6582811-6582891 33 6.59e-04 ctgacagggg ctgctgcc tttttttcag chr8:54755814-54755894 53 6.93e-04 AGGCACGTGA CTGCTGCG GAAGGCGGAA chr7:99659278-99659358 16 7.23e-04 TGACCCCCAG CAGATGGT GAGGAGAGGG chr8:23366396-23366476 27 7.23e-04 GGCCTGAGAG CAGATGGT TTCCGATATA chr5:29796334-29796414 71 7.23e-04 CCAGACACTG CAGATGGT GA chr2:158755881-158755961 18 7.23e-04 GACCTTAGAC CAGATGGT CCCTGTGGCT chr3:125152082-125152162 46 8.01e-04 agctaacttg caggtgtc tggtgatagt chrX:134996744-134996824 8 8.01e-04 ctgcagg caggtgtc atataagagg chr3:128773648-128773728 47 8.01e-04 cagttagtca catctggt ggaactgcaa chr1:224058442-224058522 43 8.01e-04 cccctccccc caggtgct ctgtcccagg chr16:21548245-21548325 60 8.71e-04 CATGAGGCCA CTGCTGTC ACACTTGGAA chr1:65487632-65487712 16 8.71e-04 ATCACTGTAA CAGGTGGA CATGGGAAAC chr1:16380761-16380841 37 8.71e-04 TCACTCAAGG CTGCTGTC AGCCCATGTG chr2:208825011-208825091 30 9.06e-04 AGATTTCTGT CTGCTGTG GTAAGAGGAC chr4:99722520-99722600 1 9.06e-04 . CTGCTGTG TCAGAGATTA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCTGYN MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:73046751-73046831 1.6e-05 62_[+3]_10 chrX:102356743-102356823 1.6e-05 64_[+3]_8 chr18:43733358-43733438 1.6e-05 40_[+3]_32 chr7:102082187-102082267 1.6e-05 6_[+3]_66 chr4:164108621-164108701 1.6e-05 26_[+3]_46 chr10:43140672-43140752 1.6e-05 55_[+3]_17 chr14:20645711-20645791 1.6e-05 58_[+3]_14 chr4:84417384-84417464 1.6e-05 1_[+3]_71 chr2:239331054-239331134 1.6e-05 39_[+3]_33 chrX:114557050-114557130 1.6e-05 49_[+3]_23 chrX:47535553-47535633 1.6e-05 72_[+3] chr3:14162510-14162590 1.6e-05 30_[+3]_42 chr19:3990351-3990431 1.6e-05 57_[+3]_15 chr4:140364982-140365062 3.3e-05 60_[+3]_12 chr13:95923475-95923555 3.3e-05 29_[+3]_43 chr7:77502862-77502942 3.3e-05 17_[+3]_55 chr17:72329122-72329202 3.3e-05 68_[+3]_4 chr7:154467934-154468014 3.3e-05 60_[+3]_12 chr10:126406635-12640671 6.6e-05 14_[+3]_58 chr8:37939618-37939698 6.6e-05 6_[+3]_66 chr8:37949357-37949437 6.6e-05 17_[+3]_55 chr15:93160909-93160989 6.6e-05 4_[+3]_68 chr22:36764689-36764769 9.8e-05 60_[+3]_12 chr15:88214710-88214790 9.8e-05 54_[+3]_18 chr1:202036418-202036498 9.8e-05 11_[+3]_61 chr1:25739903-25739983 9.8e-05 22_[+3]_50 chr1:151687987-151688067 9.8e-05 33_[+3]_39 chr14:100038917-10003899 9.8e-05 47_[+3]_25 chr1:35309375-35309455 0.00013 29_[+3]_43 chr11:6271222-6271302 0.00013 [+3]_72 chr2:58916112-58916192 0.00013 71_[+3]_1 chr22:35608152-35608232 0.00013 42_[+3]_30 chr2:17899104-17899184 0.00013 3_[+3]_69 chr7:104607707-104607787 0.00013 67_[+3]_5 chr17:31298383-31298463 0.00013 61_[+3]_11 chr9:131355492-131355572 0.00013 43_[+3]_29 chr15:39432301-39432381 0.00013 27_[+3]_45 chr11:27223269-27223349 0.00018 43_[+3]_29 chr17:14064895-14064975 0.00018 44_[+3]_28 chr11:61370697-61370777 0.00018 17_[+3]_55 chr4:154449959-154450039 0.00021 47_[+3]_25 chr12:108879359-10887943 0.00021 43_[+3]_29 chr12:32207214-32207294 0.00021 13_[+3]_59 chr1:211395914-211395994 0.00023 35_[+3]_37 chr8:49379278-49379358 0.00029 50_[+3]_22 chr19:38613549-38613629 0.00029 37_[+3]_35 chr4:25052516-25052596 0.00029 67_[+3]_5 chr17:62971008-62971088 0.00029 32_[+3]_40 chr1:95100699-95100779 0.00029 20_[+3]_52 chr19:381064-381144 0.00029 37_[+3]_35 chr18:9848292-9848372 0.00032 69_[+3]_3 chr15:75987054-75987134 0.00032 60_[+3]_12 chr6:37369593-37369673 0.00035 2_[+3]_70 chr12:48171655-48171735 0.00035 26_[+3]_46 chr13:44972146-44972226 0.00035 68_[+3]_4 chrX:55041553-55041633 0.00041 25_[+3]_47 chr21:40357698-40357778 0.00041 32_[+3]_40 chr3:142337821-142337901 0.00041 1_[+3]_71 chr16:14491344-14491424 0.00041 22_[+3]_50 chr14:24725550-24725630 0.00041 15_[+3]_57 chr6:80314382-80314462 0.00041 71_[+3]_1 chr9:69491640-69491720 0.00041 42_[+3]_30 chr8:144016038-144016118 0.00041 37_[+3]_35 chr7:72176134-72176214 0.00046 3_[+3]_69 chr11:876103-876183 0.00046 48_[+3]_24 chrX:47572300-47572380 0.00046 39_[+3]_33 chr10:63540225-63540305 0.00046 57_[+3]_15 chr1:228608968-228609048 0.00046 67_[+3]_5 chr17:62919223-62919303 0.00046 62_[+3]_10 chr8:2645853-2645933 0.00048 3_[+3]_69 chr1:109677202-109677282 0.00048 44_[+3]_28 chr15:69284224-69284304 0.00051 17_[+3]_55 chr1:6489896-6489976 0.00051 25_[+3]_47 chr2:178504421-178504501 0.00059 17_[+3]_55 chr12:65114778-65114858 0.00059 25_[+3]_47 chr12:51762652-51762732 0.00059 66_[+3]_6 chr6:159303111-159303191 0.00059 33_[+3]_39 chr14:35122459-35122539 0.00059 20_[+3]_52 chr2:172487781-172487861 0.00066 8_[+3]_64 chr7:24903955-24904035 0.00066 52_[+3]_20 chr16:10437114-10437194 0.00066 18_[+3]_54 chr19:49457982-49458062 0.00066 46_[+3]_26 chr14:36733973-36734053 0.00066 39_[+3]_33 chr3:6582811-6582891 0.00066 32_[+3]_40 chr8:54755814-54755894 0.00069 52_[+3]_20 chr7:99659278-99659358 0.00072 15_[+3]_57 chr8:23366396-23366476 0.00072 26_[+3]_46 chr5:29796334-29796414 0.00072 70_[+3]_2 chr2:158755881-158755961 0.00072 17_[+3]_55 chr3:125152082-125152162 0.0008 45_[+3]_27 chrX:134996744-134996824 0.0008 7_[+3]_65 chr3:128773648-128773728 0.0008 46_[+3]_26 chr1:224058442-224058522 0.0008 42_[+3]_30 chr16:21548245-21548325 0.00087 59_[+3]_13 chr1:65487632-65487712 0.00087 15_[+3]_57 chr1:16380761-16380841 0.00087 36_[+3]_36 chr2:208825011-208825091 0.00091 29_[+3]_43 chr4:99722520-99722600 0.00091 [+3]_72 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCTGYN MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CAGCTGYN width=8 seqs=98 chr8:73046751-73046831 ( 63) CAGCTGCA 1 chrX:102356743-102356823 ( 65) CAGCTGCA 1 chr18:43733358-43733438 ( 41) CAGCTGCA 1 chr7:102082187-102082267 ( 7) CAGCTGCA 1 chr4:164108621-164108701 ( 27) CAGCTGCA 1 chr10:43140672-43140752 ( 56) CAGCTGCA 1 chr14:20645711-20645791 ( 59) CAGCTGCA 1 chr4:84417384-84417464 ( 2) CAGCTGCA 1 chr2:239331054-239331134 ( 40) CAGCTGCA 1 chrX:114557050-114557130 ( 50) CAGCTGCA 1 chrX:47535553-47535633 ( 73) CAGCTGCA 1 chr3:14162510-14162590 ( 31) CAGCTGCA 1 chr19:3990351-3990431 ( 58) CAGCTGCA 1 chr4:140364982-140365062 ( 61) CAGCTGCC 1 chr13:95923475-95923555 ( 30) CAGCTGCC 1 chr7:77502862-77502942 ( 18) CAGCTGCC 1 chr17:72329122-72329202 ( 69) CAGCTGCC 1 chr7:154467934-154468014 ( 61) CAGCTGCC 1 chr10:126406635-12640671 ( 15) CAGCTGCG 1 chr8:37939618-37939698 ( 7) CAGCTGCG 1 chr8:37949357-37949437 ( 18) CAGCTGCG 1 chr15:93160909-93160989 ( 5) CAGCTGCG 1 chr22:36764689-36764769 ( 61) CAGCTGTC 1 chr15:88214710-88214790 ( 55) CAGCTGCT 1 chr1:202036418-202036498 ( 12) CAGCTGTC 1 chr1:25739903-25739983 ( 23) CAGCTGCT 1 chr1:151687987-151688067 ( 34) CAGCTGCT 1 chr14:100038917-10003899 ( 48) CAGCTGCT 1 chr1:35309375-35309455 ( 30) CAGCTGGA 1 chr11:6271222-6271302 ( 1) CAGCTGTG 1 chr2:58916112-58916192 ( 72) CAGCTGTG 1 chr22:35608152-35608232 ( 43) CAGCTGGA 1 chr2:17899104-17899184 ( 4) CAGCTGTG 1 chr7:104607707-104607787 ( 68) CAGCTGGA 1 chr17:31298383-31298463 ( 62) CAGCTGTG 1 chr9:131355492-131355572 ( 44) CAGCTGTG 1 chr15:39432301-39432381 ( 28) CAGCTGTG 1 chr11:27223269-27223349 ( 44) CAGCTGGC 1 chr17:14064895-14064975 ( 45) CAGCTGGC 1 chr11:61370697-61370777 ( 18) CAGCTGTT 1 chr4:154449959-154450039 ( 48) CATCTGCA 1 chr12:108879359-10887943 ( 44) CATCTGCA 1 chr12:32207214-32207294 ( 14) CATCTGCA 1 chr1:211395914-211395994 ( 36) CAGATGCC 1 chr8:49379278-49379358 ( 51) CAGATGCG 1 chr19:38613549-38613629 ( 38) CATCTGCC 1 chr4:25052516-25052596 ( 68) CAGATGCG 1 chr17:62971008-62971088 ( 33) CAGATGTA 1 chr1:95100699-95100779 ( 21) CAGCTGGT 1 chr19:381064-381144 ( 38) CAGATGTA 1 chr18:9848292-9848372 ( 70) CATCTGTA 1 chr15:75987054-75987134 ( 61) CATCTGCG 1 chr6:37369593-37369673 ( 3) CAGATGTC 1 chr12:48171655-48171735 ( 27) CAGATGCT 1 chr13:44972146-44972226 ( 69) CAGATGTC 1 chrX:55041553-55041633 ( 26) CATCTGTC 1 chr21:40357698-40357778 ( 33) CATCTGTC 1 chr3:142337821-142337901 ( 2) CAGATGTG 1 chr16:14491344-14491424 ( 23) CATCTGCT 1 chr14:24725550-24725630 ( 16) CAGATGTG 1 chr6:80314382-80314462 ( 72) CAGATGGA 1 chr9:69491640-69491720 ( 43) CATCTGTC 1 chr8:144016038-144016118 ( 38) CAGATGTG 1 chr7:72176134-72176214 ( 4) CAGGTGCA 1 chr11:876103-876183 ( 49) CAGGTGCA 1 chrX:47572300-47572380 ( 40) CAGGTGCA 1 chr10:63540225-63540305 ( 58) CATCTGGA 1 chr1:228608968-228609048 ( 68) CATCTGGA 1 chr17:62919223-62919303 ( 63) CATCTGGA 1 chr8:2645853-2645933 ( 4) CTGCTGCA 1 chr1:109677202-109677282 ( 45) CTGCTGCA 1 chr15:69284224-69284304 ( 18) CAGATGGC 1 chr1:6489896-6489976 ( 26) CAGATGGC 1 chr2:178504421-178504501 ( 18) CATCTGTT 1 chr12:65114778-65114858 ( 26) CATCTGTT 1 chr12:51762652-51762732 ( 67) CAGGTGCC 1 chr6:159303111-159303191 ( 34) CATCTGTT 1 chr14:35122459-35122539 ( 21) CAGATGGG 1 chr2:172487781-172487861 ( 9) CATCTGGG 1 chr7:24903955-24904035 ( 53) CATCTGGG 1 chr16:10437114-10437194 ( 19) CATCTGGG 1 chr19:49457982-49458062 ( 47) CAGGTGCG 1 chr14:36733973-36734053 ( 40) CTGCTGCC 1 chr3:6582811-6582891 ( 33) CTGCTGCC 1 chr8:54755814-54755894 ( 53) CTGCTGCG 1 chr7:99659278-99659358 ( 16) CAGATGGT 1 chr8:23366396-23366476 ( 27) CAGATGGT 1 chr5:29796334-29796414 ( 71) CAGATGGT 1 chr2:158755881-158755961 ( 18) CAGATGGT 1 chr3:125152082-125152162 ( 46) CAGGTGTC 1 chrX:134996744-134996824 ( 8) CAGGTGTC 1 chr3:128773648-128773728 ( 47) CATCTGGT 1 chr1:224058442-224058522 ( 43) CAGGTGCT 1 chr16:21548245-21548325 ( 60) CTGCTGTC 1 chr1:65487632-65487712 ( 16) CAGGTGGA 1 chr1:16380761-16380841 ( 37) CTGCTGTC 1 chr2:208825011-208825091 ( 30) CTGCTGTG 1 chr4:99722520-99722600 ( 1) CTGCTGTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCTGYN MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.13512 E= 7.3e-025 -1326 199 -1326 -1326 194 -1326 -1326 -138 -1326 -1326 155 -23 -29 150 -156 -1326 -1326 -1326 -1326 206 -1326 -1326 188 -1326 -1326 93 -28 30 47 2 -15 -47 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCTGYN MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 98 E= 7.3e-025 0.000000 1.000000 0.000000 0.000000 0.908163 0.000000 0.000000 0.091837 0.000000 0.000000 0.795918 0.204082 0.193878 0.714286 0.091837 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.479592 0.224490 0.295918 0.326531 0.255102 0.244898 0.173469 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGCTGYN MEME-3 regular expression -------------------------------------------------------------------------------- CA[GT]CTG[CTG][ACG] -------------------------------------------------------------------------------- Time 11.99 secs. ******************************************************************************** ******************************************************************************** MOTIF BYTTATCT MEME-4 width = 8 sites = 68 llr = 516 E-value = 3.3e-017 ******************************************************************************** -------------------------------------------------------------------------------- Motif BYTTATCT MEME-4 Description -------------------------------------------------------------------------------- Simplified A 1:::a::2 pos.-specific C 453:::a: probability G 22:::::: matrix T 338a:a:8 bits 2.1 ** 1.9 **** 1.7 **** 1.5 **** Relative 1.2 ****** Entropy 1.0 ****** (10.9 bits) 0.8 ****** 0.6 ****** 0.4 ******* 0.2 ******** 0.0 -------- Multilevel CCTTATCT consensus TTC A sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BYTTATCT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:49398944-49399024 3 1.25e-05 TT CCTTATCT TTCAGTTGCC chr2:25479546-25479626 27 1.25e-05 cccttctgtc ccttatct ttcccttctg chr6:142337964-142338044 44 2.45e-05 caccccaacc tcttatct ctgcacccca chr4:154449959-154450039 62 2.45e-05 TGCAATGGTT TCTTATCT GACCATGCAC chr1:211395914-211395994 48 2.45e-05 gatgccttcc tcttatct caactgcaaa chr17:11876223-11876303 23 2.45e-05 caccccaacc tcttatct ctgcgcccca chr1:35309375-35309455 15 3.64e-05 GGGAGGCCTC CTTTATCT CTGGCTCCAG chr10:126406635-12640671 36 3.64e-05 GCAGTGATCT CTTTATCT AGGAGGCCTG chr6:10725446-10725526 45 3.64e-05 GTTTTTGCCT CTTTATCT ACAGATAGGC chr11:124537648-12453772 55 3.64e-05 GCTTCTATAT CTTTATCT CTTCTAGACA chr6:10750099-10750179 53 3.64e-05 ATTTTTGCCT CTTTATCT AAAGGTAGGC chr3:32115895-32115975 21 3.64e-05 ttcctttact ctttatct ccagaaccca chr15:69284224-69284304 61 6.13e-05 ccttgcatgg gcttatct cataatgttc chr6:37369593-37369673 47 6.13e-05 ccttgcactg gcttatct cataaccttc chr14:20645711-20645791 37 6.13e-05 tgcaactcat gcttatct atcttgtgac chr2:173465552-173465632 30 6.13e-05 tcttcgtcca gcttatct ggaagggaga chr5:134528307-134528387 61 6.13e-05 TTGTCTCCTG GCTTATCT GAGGCCAAAA chr9:131355492-131355572 17 6.13e-05 GTCGATGACT GCTTATCT CATTGGTTGC chr3:6582811-6582891 7 6.13e-05 tggggg ttttatct ataagtccct chr1:224058442-224058522 71 6.13e-05 gagatgagca ttttatct gt chr22:36764689-36764769 35 1.14e-04 GGTGGAGGAG TGTTATCT CCCCACCCTT chr3:57584941-57585021 68 1.14e-04 tcagatatgc gtttatct cagtg chr1:27118210-27118290 36 1.14e-04 GGCTAGGGCT GTTTATCT GTGACTGTCA chr19:38613549-38613629 56 1.14e-04 atgcactgtg tgttatct gttcactgcc chr5:175624406-175624486 67 1.14e-04 gctttagctt ccctatct tagtgc chr4:68418038-68418118 44 1.14e-04 cttttagctt ccctatct tagtgcacct chr15:74902909-74902989 55 1.14e-04 TGCTTTTGGC TGTTATCT ATCACGACAG chr7:77502862-77502942 3 1.14e-04 ag tgttatct tgcctcacag chrX:79767985-79768065 11 1.14e-04 cttttagctt ccctatct tagtgtgcct chr20:33780330-33780410 35 1.14e-04 cttttagctt ccctatct tagtgcacct chr3:14162510-14162590 69 1.14e-04 cttttagctt ccctatct tagt chr12:27170378-27170458 26 1.14e-04 cttttagctt ccctatct tagtgcacct chr2:58916112-58916192 35 1.26e-04 tagataaaac tcctatct ccctgggaca chr20:30505828-30505908 6 1.26e-04 agctt tcctatct tagtgcacct chr4:164108621-164108701 64 1.26e-04 cttccacctt tcctatct tagtgtgcc chr17:31298383-31298463 34 1.39e-04 ctgggaaggt ccttatca agtgctcctg chr6:160992403-160992483 12 1.39e-04 gcagtctgtc ccttatca gagctctagt chr16:21272963-21273043 73 1.62e-04 GGCAACACAG TCTTATCA chr1:65487632-65487712 2 1.62e-04 G TCTTATCA CTGTAACAGG chr9:125209230-125209310 14 1.62e-04 caaggaaatc acttatct tctaacaata chr1:25606344-25606424 3 1.62e-04 CT TCTTATCA CCCCTGAACA chr10:47619242-47619322 20 1.62e-04 CCGGCCCGTT TCTTATCA GCAGCGTCCA chr5:112420676-112420756 17 1.89e-04 ACTATTAGTG GGTTATCT CTCCTTGCAG chr4:84417384-84417464 39 1.89e-04 cttttagctt ctctatct tagtattcct chr1:228608968-228609048 53 1.89e-04 tgctccttga ggttatct actgggacat chr7:5123114-5123194 20 1.89e-04 CATCCGGCAT GGTTATCT GCGCTTGCAA chr3:101249328-101249408 40 2.27e-04 cacccccctc ctttatca tgcagttggg chr13:39573074-39573154 51 2.63e-04 catgtgctat ttttatca ccctttgtgg chr15:88214710-88214790 65 2.63e-04 CAGCTGCTGC ATTTATCT TCTCAAAC chr6:164767856-164767936 2 2.63e-04 A ATTTATCT GGCCAGGTGG chr6:159303111-159303191 3 2.63e-04 gg gcttatca gtaatgtgaa chr8:38068316-38068396 14 2.63e-04 CACACAACAG GCTTATCA GAAACCTACC chr10:7049691-7049771 8 3.04e-04 CTTCCCA TGCTATCT CCTTAGGCCA chr18:9848292-9848372 55 3.04e-04 ccatctgtcc gtctatct atctattcat chr16:8688308-8688388 41 3.04e-04 CCAGGCACCG TGCTATCT CACTACAGCA chr14:23366707-23366787 62 3.04e-04 CACATGCCCA TGCTATCT CCCAGGGCCC chr11:2000378-2000458 14 3.17e-04 GAGAAGTCCC CGTTATCA GCAGCGAGCC chr12:53703919-53703999 22 3.68e-04 TTTTCTCTCC AGTTATCT AACACTCCTC chr1:191793071-191793151 28 3.68e-04 ATTTCAAAAA GTTTATCA TTTTGAGAAG chr12:32201010-32201090 4 3.93e-04 taa acctatct ttacacaaca chr14:35122459-35122539 59 4.46e-04 ctgataagcc ctctatca ttactgacaa chr4:69730316-69730396 37 4.97e-04 tgagcacatt ccttttct ttctggacac chr20:9129848-9129928 12 4.97e-04 accagactcc ccttttct ccacagcagc chr1:95581308-95581388 11 5.20e-04 ATGATGGTGC ATTTATCA GGAAAGAACA chr1:243269315-243269395 35 5.46e-04 gtgtccccat cctaatct catcttgaat chr1:95100699-95100779 72 5.46e-04 CAGCCAGGTC CCTAATCT C chr16:25783248-25783328 67 6.10e-04 cgttggcaaa ctttttct gtaaag chr12:58146255-58146335 41 6.10e-04 CGTGATCTGT TGCTATCA CACGTGACCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BYTTATCT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:49398944-49399024 1.3e-05 2_[+4]_70 chr2:25479546-25479626 1.3e-05 26_[+4]_46 chr6:142337964-142338044 2.4e-05 43_[+4]_29 chr4:154449959-154450039 2.4e-05 61_[+4]_11 chr1:211395914-211395994 2.4e-05 47_[+4]_25 chr17:11876223-11876303 2.4e-05 22_[+4]_50 chr1:35309375-35309455 3.6e-05 14_[+4]_58 chr10:126406635-12640671 3.6e-05 35_[+4]_37 chr6:10725446-10725526 3.6e-05 44_[+4]_28 chr11:124537648-12453772 3.6e-05 54_[+4]_18 chr6:10750099-10750179 3.6e-05 52_[+4]_20 chr3:32115895-32115975 3.6e-05 20_[+4]_52 chr15:69284224-69284304 6.1e-05 60_[+4]_12 chr6:37369593-37369673 6.1e-05 46_[+4]_26 chr14:20645711-20645791 6.1e-05 36_[+4]_36 chr2:173465552-173465632 6.1e-05 29_[+4]_43 chr5:134528307-134528387 6.1e-05 60_[+4]_12 chr9:131355492-131355572 6.1e-05 16_[+4]_56 chr3:6582811-6582891 6.1e-05 6_[+4]_66 chr1:224058442-224058522 6.1e-05 70_[+4]_2 chr22:36764689-36764769 0.00011 34_[+4]_38 chr3:57584941-57585021 0.00011 67_[+4]_5 chr1:27118210-27118290 0.00011 35_[+4]_37 chr19:38613549-38613629 0.00011 55_[+4]_17 chr5:175624406-175624486 0.00011 66_[+4]_6 chr4:68418038-68418118 0.00011 43_[+4]_29 chr15:74902909-74902989 0.00011 54_[+4]_18 chr7:77502862-77502942 0.00011 2_[+4]_70 chrX:79767985-79768065 0.00011 10_[+4]_62 chr20:33780330-33780410 0.00011 34_[+4]_38 chr3:14162510-14162590 0.00011 68_[+4]_4 chr12:27170378-27170458 0.00011 25_[+4]_47 chr2:58916112-58916192 0.00013 34_[+4]_38 chr20:30505828-30505908 0.00013 5_[+4]_67 chr4:164108621-164108701 0.00013 63_[+4]_9 chr17:31298383-31298463 0.00014 33_[+4]_39 chr6:160992403-160992483 0.00014 11_[+4]_61 chr16:21272963-21273043 0.00016 72_[+4] chr1:65487632-65487712 0.00016 1_[+4]_71 chr9:125209230-125209310 0.00016 13_[+4]_59 chr1:25606344-25606424 0.00016 2_[+4]_70 chr10:47619242-47619322 0.00016 19_[+4]_53 chr5:112420676-112420756 0.00019 16_[+4]_56 chr4:84417384-84417464 0.00019 38_[+4]_34 chr1:228608968-228609048 0.00019 52_[+4]_20 chr7:5123114-5123194 0.00019 19_[+4]_53 chr3:101249328-101249408 0.00023 39_[+4]_33 chr13:39573074-39573154 0.00026 50_[+4]_22 chr15:88214710-88214790 0.00026 64_[+4]_8 chr6:164767856-164767936 0.00026 1_[+4]_71 chr6:159303111-159303191 0.00026 2_[+4]_70 chr8:38068316-38068396 0.00026 13_[+4]_59 chr10:7049691-7049771 0.0003 7_[+4]_65 chr18:9848292-9848372 0.0003 54_[+4]_18 chr16:8688308-8688388 0.0003 40_[+4]_32 chr14:23366707-23366787 0.0003 61_[+4]_11 chr11:2000378-2000458 0.00032 13_[+4]_59 chr12:53703919-53703999 0.00037 21_[+4]_51 chr1:191793071-191793151 0.00037 27_[+4]_45 chr12:32201010-32201090 0.00039 3_[+4]_69 chr14:35122459-35122539 0.00045 58_[+4]_14 chr4:69730316-69730396 0.0005 36_[+4]_36 chr20:9129848-9129928 0.0005 11_[+4]_61 chr1:95581308-95581388 0.00052 10_[+4]_62 chr1:243269315-243269395 0.00055 34_[+4]_38 chr1:95100699-95100779 0.00055 71_[+4]_1 chr16:25783248-25783328 0.00061 66_[+4]_6 chr12:58146255-58146335 0.00061 40_[+4]_32 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BYTTATCT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF BYTTATCT width=8 seqs=68 chr3:49398944-49399024 ( 3) CCTTATCT 1 chr2:25479546-25479626 ( 27) CCTTATCT 1 chr6:142337964-142338044 ( 44) TCTTATCT 1 chr4:154449959-154450039 ( 62) TCTTATCT 1 chr1:211395914-211395994 ( 48) TCTTATCT 1 chr17:11876223-11876303 ( 23) TCTTATCT 1 chr1:35309375-35309455 ( 15) CTTTATCT 1 chr10:126406635-12640671 ( 36) CTTTATCT 1 chr6:10725446-10725526 ( 45) CTTTATCT 1 chr11:124537648-12453772 ( 55) CTTTATCT 1 chr6:10750099-10750179 ( 53) CTTTATCT 1 chr3:32115895-32115975 ( 21) CTTTATCT 1 chr15:69284224-69284304 ( 61) GCTTATCT 1 chr6:37369593-37369673 ( 47) GCTTATCT 1 chr14:20645711-20645791 ( 37) GCTTATCT 1 chr2:173465552-173465632 ( 30) GCTTATCT 1 chr5:134528307-134528387 ( 61) GCTTATCT 1 chr9:131355492-131355572 ( 17) GCTTATCT 1 chr3:6582811-6582891 ( 7) TTTTATCT 1 chr1:224058442-224058522 ( 71) TTTTATCT 1 chr22:36764689-36764769 ( 35) TGTTATCT 1 chr3:57584941-57585021 ( 68) GTTTATCT 1 chr1:27118210-27118290 ( 36) GTTTATCT 1 chr19:38613549-38613629 ( 56) TGTTATCT 1 chr5:175624406-175624486 ( 67) CCCTATCT 1 chr4:68418038-68418118 ( 44) CCCTATCT 1 chr15:74902909-74902989 ( 55) TGTTATCT 1 chr7:77502862-77502942 ( 3) TGTTATCT 1 chrX:79767985-79768065 ( 11) CCCTATCT 1 chr20:33780330-33780410 ( 35) CCCTATCT 1 chr3:14162510-14162590 ( 69) CCCTATCT 1 chr12:27170378-27170458 ( 26) CCCTATCT 1 chr2:58916112-58916192 ( 35) TCCTATCT 1 chr20:30505828-30505908 ( 6) TCCTATCT 1 chr4:164108621-164108701 ( 64) TCCTATCT 1 chr17:31298383-31298463 ( 34) CCTTATCA 1 chr6:160992403-160992483 ( 12) CCTTATCA 1 chr16:21272963-21273043 ( 73) TCTTATCA 1 chr1:65487632-65487712 ( 2) TCTTATCA 1 chr9:125209230-125209310 ( 14) ACTTATCT 1 chr1:25606344-25606424 ( 3) TCTTATCA 1 chr10:47619242-47619322 ( 20) TCTTATCA 1 chr5:112420676-112420756 ( 17) GGTTATCT 1 chr4:84417384-84417464 ( 39) CTCTATCT 1 chr1:228608968-228609048 ( 53) GGTTATCT 1 chr7:5123114-5123194 ( 20) GGTTATCT 1 chr3:101249328-101249408 ( 40) CTTTATCA 1 chr13:39573074-39573154 ( 51) TTTTATCA 1 chr15:88214710-88214790 ( 65) ATTTATCT 1 chr6:164767856-164767936 ( 2) ATTTATCT 1 chr6:159303111-159303191 ( 3) GCTTATCA 1 chr8:38068316-38068396 ( 14) GCTTATCA 1 chr10:7049691-7049771 ( 8) TGCTATCT 1 chr18:9848292-9848372 ( 55) GTCTATCT 1 chr16:8688308-8688388 ( 41) TGCTATCT 1 chr14:23366707-23366787 ( 62) TGCTATCT 1 chr11:2000378-2000458 ( 14) CGTTATCA 1 chr12:53703919-53703999 ( 22) AGTTATCT 1 chr1:191793071-191793151 ( 28) GTTTATCA 1 chr12:32201010-32201090 ( 4) ACCTATCT 1 chr14:35122459-35122539 ( 59) CTCTATCA 1 chr4:69730316-69730396 ( 37) CCTTTTCT 1 chr20:9129848-9129928 ( 12) CCTTTTCT 1 chr1:95581308-95581388 ( 11) ATTTATCA 1 chr1:243269315-243269395 ( 35) CCTAATCT 1 chr1:95100699-95100779 ( 72) CCTAATCT 1 chr16:25783248-25783328 ( 67) CTTTTTCT 1 chr12:58146255-58146335 ( 41) TGCTATCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BYTTATCT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.85972 E= 3.3e-017 -142 54 -30 43 -1273 103 -51 30 -1273 -1 -1273 165 -301 -1273 -1273 202 202 -1273 -1273 -244 -1273 -1273 -1273 206 -1273 199 -1273 -1273 -10 -1273 -1273 170 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BYTTATCT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 68 E= 3.3e-017 0.088235 0.367647 0.220588 0.323529 0.000000 0.514706 0.191176 0.294118 0.000000 0.250000 0.000000 0.750000 0.029412 0.000000 0.000000 0.970588 0.955882 0.000000 0.000000 0.044118 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.220588 0.000000 0.000000 0.779412 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BYTTATCT MEME-4 regular expression -------------------------------------------------------------------------------- [CTG][CT][TC]TATC[TA] -------------------------------------------------------------------------------- Time 15.31 secs. ******************************************************************************** ******************************************************************************** MOTIF CACGTGAC MEME-5 width = 8 sites = 20 llr = 205 E-value = 4.6e-009 ******************************************************************************** -------------------------------------------------------------------------------- Motif CACGTGAC MEME-5 Description -------------------------------------------------------------------------------- Simplified A :a:1::a: pos.-specific C a:8::::a probability G :::9:a:: matrix T ::2:a::: bits 2.1 ** * ** 1.9 ** **** 1.7 ** **** 1.5 ** ***** Relative 1.2 ******** Entropy 1.0 ******** (14.8 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CACGTGAC consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGAC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:56109776-56109856 52 1.58e-05 ACACAGCGGT CACGTGAC ATGGCCCCGG chr11:67159292-67159372 52 1.58e-05 CGTGCGCCGT CACGTGAC GGCAGAGCCT chr7:4815190-4815270 27 1.58e-05 TGTGATGCGG CACGTGAC GCAGCCACGT chr12:58146255-58146335 49 1.58e-05 GTTGCTATCA CACGTGAC CGCTTGACAT chr19:7587441-7587521 55 1.58e-05 GCTACCGGGT CACGTGAC CGAGGCACAG chr5:150827102-150827182 19 1.58e-05 CTCAAGGGAG CACGTGAC CTCGGCCTCT chr1:11866206-11866286 22 1.58e-05 TCGAGAGGGC CACGTGAC CGTCCCGGGG chr10:46222589-46222669 51 1.58e-05 CGGGTTCTGT CACGTGAC ATCAGGTCAC chr12:65153196-65153276 51 1.58e-05 GCTGCGCGGT CACGTGAC GGCCGGCGTG chr19:49457982-49458062 57 1.58e-05 CAGGTGCGGT CACGTGAC CCGGCGGCGC chr17:6915640-6915720 46 1.58e-05 CAGGCTTGGT CACGTGAC ATACCAGCTC chr19:40854416-40854496 51 1.58e-05 TCGTAACCGT CACGTGAC CGCCCACCGT chr17:7137857-7137937 64 1.58e-05 CCCTCCCAAT CACGTGAC CGTCTGACT chr4:10497402-10497482 2 1.58e-05 t cacgtgac catagagaga chr22:31365122-31365202 14 3.09e-05 TGCGTGTCCC CATGTGAC CGGATCTTGG chr13:50420831-50420911 32 3.09e-05 ATGATACCAG CATGTGAC ATGAGAGATC chr9:136159287-136159367 40 3.09e-05 ggtttctccc catgtgac agcctgagat chr7:154467934-154468014 1 3.09e-05 . CATGTGAC CTGCTACACA chr1:155211032-155211112 50 4.46e-05 CTAGGAGCGT CACATGAC ACAGGAAGTG chr1:155188793-155188873 51 4.46e-05 CTAGGAGAGT CACATGAC ACAGGAAGTG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGAC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:56109776-56109856 1.6e-05 51_[+5]_21 chr11:67159292-67159372 1.6e-05 51_[+5]_21 chr7:4815190-4815270 1.6e-05 26_[+5]_46 chr12:58146255-58146335 1.6e-05 48_[+5]_24 chr19:7587441-7587521 1.6e-05 54_[+5]_18 chr5:150827102-150827182 1.6e-05 18_[+5]_54 chr1:11866206-11866286 1.6e-05 21_[+5]_51 chr10:46222589-46222669 1.6e-05 50_[+5]_22 chr12:65153196-65153276 1.6e-05 50_[+5]_22 chr19:49457982-49458062 1.6e-05 56_[+5]_16 chr17:6915640-6915720 1.6e-05 45_[+5]_27 chr19:40854416-40854496 1.6e-05 50_[+5]_22 chr17:7137857-7137937 1.6e-05 63_[+5]_9 chr4:10497402-10497482 1.6e-05 1_[+5]_71 chr22:31365122-31365202 3.1e-05 13_[+5]_59 chr13:50420831-50420911 3.1e-05 31_[+5]_41 chr9:136159287-136159367 3.1e-05 39_[+5]_33 chr7:154467934-154468014 3.1e-05 [+5]_72 chr1:155211032-155211112 4.5e-05 49_[+5]_23 chr1:155188793-155188873 4.5e-05 50_[+5]_22 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGAC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CACGTGAC width=8 seqs=20 chr12:56109776-56109856 ( 52) CACGTGAC 1 chr11:67159292-67159372 ( 52) CACGTGAC 1 chr7:4815190-4815270 ( 27) CACGTGAC 1 chr12:58146255-58146335 ( 49) CACGTGAC 1 chr19:7587441-7587521 ( 55) CACGTGAC 1 chr5:150827102-150827182 ( 19) CACGTGAC 1 chr1:11866206-11866286 ( 22) CACGTGAC 1 chr10:46222589-46222669 ( 51) CACGTGAC 1 chr12:65153196-65153276 ( 51) CACGTGAC 1 chr19:49457982-49458062 ( 57) CACGTGAC 1 chr17:6915640-6915720 ( 46) CACGTGAC 1 chr19:40854416-40854496 ( 51) CACGTGAC 1 chr17:7137857-7137937 ( 64) CACGTGAC 1 chr4:10497402-10497482 ( 2) CACGTGAC 1 chr22:31365122-31365202 ( 14) CATGTGAC 1 chr13:50420831-50420911 ( 32) CATGTGAC 1 chr9:136159287-136159367 ( 40) CATGTGAC 1 chr7:154467934-154468014 ( 1) CATGTGAC 1 chr1:155211032-155211112 ( 50) CACATGAC 1 chr1:155188793-155188873 ( 51) CACATGAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGAC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0839 E= 4.6e-009 -1097 199 -1097 -1097 208 -1097 -1097 -1097 -1097 166 -1097 -26 -124 -1097 173 -1097 -1097 -1097 -1097 206 -1097 -1097 188 -1097 208 -1097 -1097 -1097 -1097 199 -1097 -1097 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGAC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 20 E= 4.6e-009 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.200000 0.100000 0.000000 0.900000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CACGTGAC MEME-5 regular expression -------------------------------------------------------------------------------- CA[CT]GTGAC -------------------------------------------------------------------------------- Time 18.53 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:10497402-10497482 1.67e-04 [+1(1.51e-05)]_26_[+1(1.51e-05)]_28_\ [+1(1.51e-05)]_2 chr19:381064-381144 1.01e-01 80 chr14:88491088-88491168 7.99e-02 68_[+2(1.30e-05)]_4 chr7:7082287-7082367 5.28e-01 80 chr17:7137857-7137937 1.12e-04 43_[+1(1.51e-05)]_11_[+1(1.51e-05)]_\ 10 chr8:144016038-144016118 1.48e-02 80 chr19:3990351-3990431 7.93e-06 42_[+1(1.51e-05)]_7_[+3(1.58e-05)]_\ 15 chr7:154467934-154468014 1.55e-03 [+5(3.09e-05)]_52_[+3(3.27e-05)]_12 chr13:49684356-49684436 1.93e-04 23_[+1(1.51e-05)]_6_[+1(1.51e-05)]_\ 35 chr10:47619242-47619322 2.02e-01 80 chr1:224058442-224058522 4.11e-03 70_[+4(6.13e-05)]_2 chr2:158755881-158755961 1.59e-01 80 chr4:144940569-144940649 3.50e-01 80 chr10:70883886-70883966 1.02e-03 27_[+1(7.51e-05)]_16_[+1(1.51e-05)]_\ 21 chr14:20923291-20923371 1.73e-04 48_[+1(1.51e-05)]_24 chr14:100038917-10003899 9.48e-05 47_[+3(9.82e-05)]_25 chr1:6489896-6489976 1.13e-01 80 chr6:160992403-160992483 9.19e-02 80 chr14:35122459-35122539 2.50e-03 80 chr11:61370697-61370777 1.64e-01 80 chr19:40854416-40854496 2.24e-03 4_[+1(1.51e-05)]_37_[+1(1.51e-05)]_\ 23 chr17:62919223-62919303 2.38e-01 80 chr12:27170378-27170458 7.60e-02 80 chr3:14162510-14162590 5.83e-03 30_[+3(1.58e-05)]_42 chrX:47535553-47535633 9.71e-04 72_[+3(1.58e-05)] chr11:2000378-2000458 1.12e-01 80 chr17:6915640-6915720 3.92e-04 22_[+1(1.51e-05)]_14_[+1(1.51e-05)]_\ 28 chr17:72329122-72329202 1.80e-03 68_[+3(3.27e-05)]_4 chr15:75987054-75987134 7.98e-02 80 chr1:25611725-25611805 2.03e-01 80 chr3:6582811-6582891 3.84e-03 6_[+4(6.13e-05)]_66 chr17:11876223-11876303 2.01e-01 22_[+4(2.45e-05)]_34_[+4(2.45e-05)]_\ 8 chr1:211395914-211395994 1.03e-03 47_[+4(2.45e-05)]_25 chr3:32115895-32115975 4.82e-04 20_[+4(3.64e-05)]_52 chr9:69491640-69491720 4.93e-03 28_[+2(1.30e-05)]_44 chr12:32207214-32207294 6.13e-02 80 chr15:39432301-39432381 1.53e-02 80 chr9:131355492-131355572 4.15e-03 16_[+4(6.13e-05)]_56 chr6:10750099-10750179 1.26e-02 52_[+4(3.64e-05)]_20 chr1:207020987-207021067 1.57e-01 80 chr5:134528307-134528387 7.01e-02 60_[+4(6.13e-05)]_12 chr7:139935100-139935180 1.52e-01 80 chr14:23366707-23366787 1.32e-03 22_[+2(2.80e-05)]_50 chr2:240008152-240008232 2.42e-01 80 chr1:25606344-25606424 1.64e-02 80 chr14:36733973-36734053 2.10e-02 80 chr19:49457982-49458062 1.82e-04 10_[+1(1.51e-05)]_37_[+1(1.51e-05)]_\ 17 chr1:151687987-151688067 1.67e-02 38_[+4(6.13e-05)]_34 chr4:99722520-99722600 1.03e-01 80 chr8:38068316-38068396 1.86e-02 80 chr5:139990836-139990916 5.24e-01 80 chr11:124537648-12453772 7.82e-02 54_[+4(3.64e-05)]_18 chr1:160919142-160919222 4.80e-01 80 chr20:9129848-9129928 1.01e-01 80 chr2:208825011-208825091 1.55e-01 80 chr20:33780330-33780410 6.90e-02 80 chr1:16380761-16380841 1.27e-02 80 chr16:57220078-57220158 5.62e-04 46_[+1(1.51e-05)]_26 chr13:99628350-99628430 3.08e-01 80 chr16:10437114-10437194 2.51e-02 45_[+2(4.19e-05)]_27 chr3:129512923-129513003 5.83e-04 23_[+3(1.58e-05)]_49 chr7:24903955-24904035 4.70e-01 80 chrX:79767985-79768065 3.44e-01 80 chr4:144826776-144826856 8.46e-02 80 chr11:34258304-34258384 9.53e-02 80 chr19:516724-516804 3.14e-01 80 chr1:95100699-95100779 4.19e-02 80 chr7:5123114-5123194 6.96e-02 80 chr9:125209230-125209310 2.55e-03 61_[+2(1.30e-05)]_11 chr17:31298383-31298463 5.63e-03 80 chr19:35411464-35411544 7.98e-01 80 chr8:98790773-98790853 5.74e-01 80 chr1:228608968-228609048 7.20e-02 80 chr2:173465552-173465632 2.36e-01 29_[+4(6.13e-05)]_43 chr12:65153196-65153276 9.36e-04 9_[+1(1.51e-05)]_32_[+1(1.51e-05)]_\ 23 chr6:80314382-80314462 3.74e-02 80 chr1:228366648-228366728 3.79e-01 80 chr9:102907625-102907705 1.43e-01 6_[+2(1.30e-05)]_33_[+2(1.30e-05)]_\ 25 chrX:114557050-114557130 1.26e-03 49_[+3(1.58e-05)]_1_[+2(1.30e-05)]_\ 14 chr12:125369563-12536964 5.74e-01 80 chr2:239331054-239331134 5.55e-05 39_[+3(1.58e-05)]_1_[+1(7.51e-05)]_\ 24 chr17:62971008-62971088 1.91e-02 80 chr4:103277044-103277124 4.74e-01 80 chr7:77502862-77502942 3.09e-03 17_[+3(3.27e-05)]_55 chr4:84417384-84417464 2.28e-03 1_[+3(1.58e-05)]_71 chr1:155188793-155188873 8.58e-04 29_[+1(2.94e-05)]_13_[+5(4.46e-05)]_\ 22 chr10:46222589-46222669 3.47e-04 49_[+1(1.51e-05)]_7_[+1(1.51e-05)]_\ 8 chr5:112420676-112420756 1.42e-01 80 chr4:1884770-1884850 1.55e-01 80 chr5:29796334-29796414 2.41e-03 80 chrX:55054625-55054705 1.68e-01 7_[+2(6.61e-05)]_65 chr15:74902909-74902989 9.62e-02 80 chr3:177148568-177148648 7.03e-02 80 chr7:916018-916098 1.69e-01 22_[+1(7.51e-05)]_22_[+1(7.51e-05)]_\ 20 chr5:176075751-176075831 1.20e-01 80 chr10:63540225-63540305 2.78e-02 48_[+2(6.61e-05)]_24 chr17:14064895-14064975 1.87e-02 70_[+2(6.61e-05)]_2 chr15:93160909-93160989 1.75e-04 4_[+3(6.60e-05)]_56_[+2(6.61e-05)]_\ 4 chr3:196715531-196715611 3.98e-01 80 chr1:191793071-191793151 3.29e-01 80 chr3:128773648-128773728 4.58e-01 80 chr9:136159287-136159367 2.58e-03 39_[+5(3.09e-05)]_33 chr5:32288427-32288507 2.33e-02 80 chr13:50420831-50420911 2.35e-02 31_[+5(3.09e-05)]_41 chr17:46625711-46625791 2.85e-04 49_[+1(1.51e-05)]_23 chr13:44956980-44957060 4.57e-02 8_[+2(2.80e-05)]_64 chr14:20645711-20645791 3.86e-05 36_[+4(6.13e-05)]_14_[+3(1.58e-05)]_\ 14 chr1:109677202-109677282 2.92e-02 80 chr19:12833507-12833587 1.67e-04 45_[+1(1.51e-05)]_27 chr13:44972146-44972226 1.10e-01 80 chr16:28503368-28503448 3.99e-04 21_[+1(1.51e-05)]_51 chr16:10591142-10591222 3.89e-02 80 chr1:110881786-110881866 3.37e-04 30_[+1(1.51e-05)]_42 chr22:31365122-31365202 5.36e-04 13_[+5(3.09e-05)]_29_[+1(1.51e-05)]_\ 22 chr8:37949357-37949437 6.03e-02 17_[+3(6.60e-05)]_55 chr1:11866206-11866286 8.43e-04 21_[+5(1.58e-05)]_14_[+1(1.51e-05)]_\ 29 chr4:69730316-69730396 8.41e-02 80 chr20:3890852-3890932 8.97e-01 80 chr7:104607707-104607787 9.55e-04 6_[+2(2.80e-05)]_66 chr5:150827102-150827182 1.66e-04 18_[+5(1.58e-05)]_26_[+1(1.51e-05)]_\ 20 chr14:24725550-24725630 3.87e-02 80 chr16:8688308-8688388 2.32e-01 80 chr11:126081591-12608167 1.32e-01 80 chr10:43140672-43140752 4.95e-02 55_[+3(1.58e-05)]_17 chr1:65487632-65487712 5.80e-04 80 chr1:35602536-35602616 1.64e-01 36_[+2(1.30e-05)]_36 chr6:16263874-16263954 1.20e-01 15_[+2(1.30e-05)]_34_[+2(1.30e-05)]_\ 15 chr6:159303111-159303191 3.98e-04 67_[+2(6.61e-05)]_5 chrX:47543023-47543103 6.20e-02 80 chr10:13747870-13747950 8.09e-01 80 chr16:14491344-14491424 8.99e-02 80 chr4:164108621-164108701 7.94e-03 26_[+3(1.58e-05)]_46 chr11:27223269-27223349 2.04e-01 80 chr21:45937290-45937370 8.73e-04 16_[+1(2.94e-05)]_56 chr10:75690637-75690717 5.06e-04 50_[+1(1.51e-05)]_22 chr1:155211032-155211112 1.71e-04 28_[+1(2.94e-05)]_13_[+5(4.46e-05)]_\ 23 chr1:25739903-25739983 8.96e-03 22_[+3(9.82e-05)]_50 chr19:7587441-7587521 2.80e-04 26_[+1(1.51e-05)]_19_[+1(1.51e-05)]_\ 19 chr4:25052516-25052596 2.04e-02 80 chr6:112126195-112126275 5.18e-01 80 chr2:17899104-17899184 1.17e-02 80 chrX:134996744-134996824 6.03e-02 80 chr6:152554081-152554161 2.85e-01 80 chr9:117349941-117350021 1.63e-04 48_[+1(1.51e-05)]_24 chr18:9848292-9848372 2.29e-02 80 chr6:164767856-164767936 2.50e-03 80 chr4:68418038-68418118 7.60e-02 80 chr5:175624406-175624486 1.58e-01 80 chr8:37939618-37939698 3.02e-03 6_[+3(6.60e-05)]_57_[+2(2.80e-05)]_\ 1 chr20:32007072-32007152 1.51e-01 80 chr7:102082187-102082267 8.15e-03 6_[+3(1.58e-05)]_66 chrX:47572300-47572380 4.18e-03 50_[+2(2.80e-05)]_22 chr5:1067949-1068029 4.19e-01 80 chr3:125152082-125152162 1.90e-02 80 chr12:51762652-51762732 2.00e-01 80 chr12:120755546-12075562 4.57e-04 48_[+1(1.51e-05)]_24 chr12:108879359-10887943 1.14e-03 80 chr3:142337821-142337901 2.17e-02 80 chr19:41256412-41256492 1.05e-04 50_[+1(1.51e-05)]_22 chr1:70005908-70005988 1.46e-02 80 chr2:25479546-25479626 4.32e-02 6_[+4(1.25e-05)]_12_[+4(1.25e-05)]_\ 12_[+4(1.25e-05)]_26 chr20:30505828-30505908 7.87e-02 80 chr22:35608152-35608232 9.62e-04 25_[+2(5.31e-05)]_47 chr12:58146255-58146335 4.69e-04 48_[+5(1.58e-05)]_24 chr19:38613549-38613629 1.71e-02 80 chr13:44961220-44961300 2.22e-01 80 chr15:31270664-31270744 7.79e-02 46_[+2(2.80e-05)]_26 chr1:95581308-95581388 3.74e-01 80 chr17:26854456-26854536 5.48e-03 29_[+2(2.80e-05)]_43 chr8:10653575-10653655 1.77e-01 80 chr12:32201010-32201090 1.53e-02 80 chr4:154449959-154450039 4.31e-05 61_[+4(2.45e-05)]_11 chr10:7049691-7049771 7.99e-02 80 chr5:111885592-111885672 9.56e-02 80 chr10:134956864-13495694 1.35e-01 80 chr13:95923475-95923555 5.95e-03 29_[+3(3.27e-05)]_43 chr8:23366396-23366476 8.35e-02 80 chr11:62645235-62645315 3.47e-02 80 chr9:4862952-4863032 2.89e-02 80 chr16:21272963-21273043 1.34e-01 80 chr1:27118210-27118290 2.85e-02 80 chr21:40357698-40357778 3.81e-02 80 chr2:172487781-172487861 6.32e-03 35_[+2(1.30e-05)]_37 chr2:58916112-58916192 2.78e-04 25_[+2(5.31e-05)]_47 chr12:65114778-65114858 9.07e-03 80 chrX:55041553-55041633 3.87e-03 72_[+2(8.11e-05)] chr8:109455800-109455880 3.47e-04 32_[+1(1.51e-05)]_40 chr11:62136580-62136660 4.87e-01 80 chr7:100271058-100271138 4.82e-04 44_[+1(1.51e-05)]_28 chr8:2645853-2645933 3.38e-02 41_[+2(8.11e-05)]_31 chr3:57584941-57585021 4.53e-02 80 chr12:48171655-48171735 7.86e-03 80 chr16:21548245-21548325 1.11e-02 40_[+2(2.80e-05)]_32 chr4:145061883-145061963 8.46e-02 80 chr7:99659278-99659358 4.89e-01 80 chr17:47841775-47841855 6.33e-04 48_[+1(1.51e-05)]_24 chr11:5618011-5618091 2.61e-01 80 chr1:180182659-180182739 8.98e-05 48_[+1(1.51e-05)]_24 chr18:75034037-75034117 9.97e-02 80 chr11:876103-876183 3.17e-02 61_[+2(4.19e-05)]_11 chr11:61109835-61109915 2.79e-01 80 chr8:54755814-54755894 1.13e-04 30_[+1(1.51e-05)]_7_[+5(1.58e-05)]_\ 27 chr6:142337964-142338044 2.13e-01 1_[+4(2.45e-05)]_34_[+4(2.45e-05)]_\ 29 chr5:150845260-150845340 2.05e-02 57_[+2(8.11e-05)]_15 chr18:43733358-43733438 1.48e-03 40_[+3(1.58e-05)]_32 chr1:243269315-243269395 5.31e-01 80 chr7:4815190-4815270 4.53e-04 13_[+1(2.94e-05)]_5_[+5(1.58e-05)]_\ 23_[+1(1.51e-05)]_15 chr7:39849956-39850036 7.31e-02 80 chr16:25783248-25783328 1.73e-02 31_[+2(8.11e-05)]_41 chr6:37369593-37369673 1.30e-02 46_[+4(6.13e-05)]_26 chr11:85780158-85780238 1.17e-03 9_[+1(1.51e-05)]_63 chr18:67693009-67693089 5.68e-01 80 chr1:202036418-202036498 3.54e-02 11_[+3(9.82e-05)]_61 chr15:72668338-72668418 2.72e-04 24_[+1(7.51e-05)]_27_[+1(1.51e-05)]_\ 13 chr8:49379278-49379358 1.95e-03 67_[+2(1.30e-05)]_5 chr11:6271222-6271302 8.28e-03 52_[+2(6.61e-05)]_20 chr6:10725446-10725526 1.35e-02 44_[+4(3.64e-05)]_28 chr5:178110920-178111000 9.78e-03 5_[+2(1.30e-05)]_67 chr20:37192600-37192680 7.59e-01 80 chr10:43142673-43142753 2.47e-01 80 chr3:152949161-152949241 1.20e-01 31_[+2(1.30e-05)]_41 chr5:149879215-149879295 9.21e-02 44_[+2(4.19e-05)]_28 chr2:174939672-174939752 4.71e-01 80 chr8:93107691-93107771 8.38e-01 80 chr9:132875221-132875301 4.51e-02 39_[+1(4.35e-05)]_33 chr11:67159292-67159372 1.91e-03 21_[+1(1.51e-05)]_21_[+1(1.51e-05)]_\ 22 chr13:19398952-19399032 2.74e-02 39_[+2(2.80e-05)]_33 chr2:128300681-128300761 2.55e-01 80 chr17:19913665-19913745 5.35e-02 4_[+2(6.61e-05)]_68 chr15:88214710-88214790 2.46e-02 54_[+3(9.82e-05)]_18 chr14:103844542-10384462 6.56e-01 80 chrX:102356743-102356823 3.74e-03 14_[+2(2.80e-05)]_42_[+3(1.58e-05)]_\ 8 chr19:14502094-14502174 4.48e-03 80 chr12:56109776-56109856 4.85e-04 34_[+1(1.51e-05)]_8_[+1(1.51e-05)]_\ 22 chr8:73046751-73046831 2.05e-04 43_[+2(2.80e-05)]_11_[+3(1.58e-05)]_\ 10 chr15:75628333-75628413 3.33e-03 24_[+1(1.51e-05)]_48 chr15:69284224-69284304 5.53e-03 60_[+4(6.13e-05)]_12 chr3:49398944-49399024 4.95e-03 2_[+4(1.25e-05)]_70 chr10:126406635-12640671 7.75e-03 14_[+3(6.60e-05)]_13_[+4(3.64e-05)]_\ 37 chr12:53703919-53703999 2.74e-01 80 chr7:157195949-157196029 7.66e-01 80 chr3:101249328-101249408 2.87e-01 80 chr22:36764689-36764769 5.30e-04 60_[+3(9.82e-05)]_12 chr12:28345243-28345323 6.45e-01 80 chr2:178504421-178504501 3.22e-02 80 chr13:39573074-39573154 1.50e-02 80 chr4:140364982-140365062 4.05e-03 60_[+3(3.27e-05)]_12 chr1:35309375-35309455 6.37e-03 14_[+4(3.64e-05)]_58 chr7:72176134-72176214 2.16e-02 80 chr4:145000048-145000128 3.34e-02 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n10.farnam.hpc.yale.internal ********************************************************************************