******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/BMI1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr3:179615939-179616019 1.0000 80 chr19:51243474-51243554 1.0000 80 chr1:201622493-201622573 1.0000 80 chr19:42500248-42500328 1.0000 80 chr19:3271065-3271145 1.0000 80 chr8:125622624-125622704 1.0000 80 chr9:129486225-129486305 1.0000 80 chr7:100087583-100087663 1.0000 80 chr11:62537436-62537516 1.0000 80 chr19:1860182-1860262 1.0000 80 chr19:47972051-47972131 1.0000 80 chr19:46981762-46981842 1.0000 80 chr2:198799163-198799243 1.0000 80 chr20:5695346-5695426 1.0000 80 chr17:42905348-42905428 1.0000 80 chr10:43818326-43818406 1.0000 80 chr2:241771942-241772022 1.0000 80 chr1:207884842-207884922 1.0000 80 chr1:201643320-201643400 1.0000 80 chr17:7117370-7117450 1.0000 80 chr1:21525610-21525690 1.0000 80 chr1:159869921-159870001 1.0000 80 chr17:58239103-58239183 1.0000 80 chr7:137846440-137846520 1.0000 80 chr22:32360094-32360174 1.0000 80 chr20:30085820-30085900 1.0000 80 chr3:41236359-41236439 1.0000 80 chr7:35077221-35077301 1.0000 80 chr20:42072889-42072969 1.0000 80 chr3:156227740-156227820 1.0000 80 chr7:130833662-130833742 1.0000 80 chr1:42814313-42814393 1.0000 80 chr1:20335073-20335153 1.0000 80 chr17:47753699-47753779 1.0000 80 chr20:1404636-1404716 1.0000 80 chr8:26482876-26482956 1.0000 80 chr3:41238212-41238292 1.0000 80 chr7:100104305-100104385 1.0000 80 chr1:26459157-26459237 1.0000 80 chr8:30294209-30294289 1.0000 80 chr19:17012772-17012852 1.0000 80 chr18:19747862-19747942 1.0000 80 chr16:86928668-86928748 1.0000 80 chr19:14411305-14411385 1.0000 80 chr20:57663023-57663103 1.0000 80 chr19:15334361-15334441 1.0000 80 chr19:11484375-11484455 1.0000 80 chr5:149893451-149893531 1.0000 80 chr9:129482090-129482170 1.0000 80 chr1:25254680-25254760 1.0000 80 chr3:167098101-167098181 1.0000 80 chr7:155414274-155414354 1.0000 80 chr19:39536863-39536943 1.0000 80 chr12:54653403-54653483 1.0000 80 chr8:22858358-22858438 1.0000 80 chr19:6066794-6066874 1.0000 80 chr2:11531853-11531933 1.0000 80 chr8:72754915-72754995 1.0000 80 chr1:110163572-110163652 1.0000 80 chr10:3916061-3916141 1.0000 80 chr16:29675603-29675683 1.0000 80 chr7:99699532-99699612 1.0000 80 chrX:71314903-71314983 1.0000 80 chr11:76758786-76758866 1.0000 80 chr20:5639682-5639762 1.0000 80 chr17:46826608-46826688 1.0000 80 chr19:55690776-55690856 1.0000 80 chr8:57119854-57119934 1.0000 80 chr7:32945097-32945177 1.0000 80 chr12:9066910-9066990 1.0000 80 chr2:101476528-101476608 1.0000 80 chr6:53357777-53357857 1.0000 80 chr3:142608506-142608586 1.0000 80 chr7:36401005-36401085 1.0000 80 chr17:64188279-64188359 1.0000 80 chr11:125387190-12538727 1.0000 80 chr14:29247992-29248072 1.0000 80 chr7:27251511-27251591 1.0000 80 chr18:20773854-20773934 1.0000 80 chr10:103157018-10315709 1.0000 80 chr17:38375048-38375128 1.0000 80 chr18:44577006-44577086 1.0000 80 chr1:212748862-212748942 1.0000 80 chr8:95656926-95657006 1.0000 80 chr6:25988235-25988315 1.0000 80 chr9:35114226-35114306 1.0000 80 chr7:100273249-100273329 1.0000 80 chr5:43193865-43193945 1.0000 80 chr22:39615565-39615645 1.0000 80 chr16:30959615-30959695 1.0000 80 chr5:108804597-108804677 1.0000 80 chr20:11873038-11873118 1.0000 80 chr6:11055474-11055554 1.0000 80 chr1:180207343-180207423 1.0000 80 chr1:212720568-212720648 1.0000 80 chr16:81554877-81554957 1.0000 80 chr19:47250073-47250153 1.0000 80 chr1:151682829-151682909 1.0000 80 chr8:57114896-57114976 1.0000 80 chr5:176884805-176884885 1.0000 80 chr11:118528049-11852812 1.0000 80 chrX:133938031-133938111 1.0000 80 chr3:13084547-13084627 1.0000 80 chr16:759701-759781 1.0000 80 chr2:74648739-74648819 1.0000 80 chr3:138048641-138048721 1.0000 80 chr2:23610861-23610941 1.0000 80 chr7:45129090-45129170 1.0000 80 chr5:179364025-179364105 1.0000 80 chr1:100817825-100817905 1.0000 80 chrX:119130175-119130255 1.0000 80 chr12:116944238-11694431 1.0000 80 chr11:15988797-15988877 1.0000 80 chr6:36313997-36314077 1.0000 80 chr4:47688435-47688515 1.0000 80 chr3:11759646-11759726 1.0000 80 chr5:79330452-79330532 1.0000 80 chr1:207752863-207752943 1.0000 80 chr11:34673287-34673367 1.0000 80 chr12:96883287-96883367 1.0000 80 chr20:34652621-34652701 1.0000 80 chr19:28887377-28887457 1.0000 80 chr7:28101881-28101961 1.0000 80 chr11:65951332-65951412 1.0000 80 chr1:12719160-12719240 1.0000 80 chr3:59035848-59035928 1.0000 80 chr19:720204-720284 1.0000 80 chr17:46226864-46226944 1.0000 80 chr12:6716690-6716770 1.0000 80 chr14:60043518-60043598 1.0000 80 chr1:202318488-202318568 1.0000 80 chr11:1918258-1918338 1.0000 80 chr5:36729003-36729083 1.0000 80 chr3:11683500-11683580 1.0000 80 chr15:72598732-72598812 1.0000 80 chr17:7117995-7118075 1.0000 80 chr19:9945425-9945505 1.0000 80 chr11:34289110-34289190 1.0000 80 chr17:49205584-49205664 1.0000 80 chr19:18263385-18263465 1.0000 80 chr19:56098763-56098843 1.0000 80 chr1:15735938-15736018 1.0000 80 chr8:27696610-27696690 1.0000 80 chr2:160664116-160664196 1.0000 80 chr12:109548827-10954890 1.0000 80 chr7:157100714-157100794 1.0000 80 chr2:232469502-232469582 1.0000 80 chr8:30515831-30515911 1.0000 80 chr2:64632073-64632153 1.0000 80 chr8:107281711-107281791 1.0000 80 chr7:617674-617754 1.0000 80 chr17:7108225-7108305 1.0000 80 chr1:155804460-155804540 1.0000 80 chr7:120975086-120975166 1.0000 80 chr19:13842452-13842532 1.0000 80 chr10:71848223-71848303 1.0000 80 chr21:43916464-43916544 1.0000 80 chr12:76486317-76486397 1.0000 80 chr17:74137366-74137446 1.0000 80 chr7:101397802-101397882 1.0000 80 chr7:16503299-16503379 1.0000 80 chr16:58529163-58529243 1.0000 80 chr1:208267816-208267896 1.0000 80 chr1:39564347-39564427 1.0000 80 chr17:9479909-9479989 1.0000 80 chr8:28354394-28354474 1.0000 80 chr17:17566783-17566863 1.0000 80 chr6:16410065-16410145 1.0000 80 chr1:24345454-24345534 1.0000 80 chr2:219221525-219221605 1.0000 80 chr1:33546612-33546692 1.0000 80 chr12:54443256-54443336 1.0000 80 chr2:204192893-204192973 1.0000 80 chr19:14492940-14493020 1.0000 80 chr22:20969886-20969966 1.0000 80 chr9:130856745-130856825 1.0000 80 chr17:44855449-44855529 1.0000 80 chr19:50554342-50554422 1.0000 80 chr9:136070174-136070254 1.0000 80 chr20:1305899-1305979 1.0000 80 chr18:3013516-3013596 1.0000 80 chr7:130834424-130834504 1.0000 80 chr1:21716394-21716474 1.0000 80 chr22:38453088-38453168 1.0000 80 chr5:88025335-88025415 1.0000 80 chr18:12904071-12904151 1.0000 80 chr3:129033833-129033913 1.0000 80 chr7:17274216-17274296 1.0000 80 chr19:17854832-17854912 1.0000 80 chr19:55850574-55850654 1.0000 80 chr6:157274853-157274933 1.0000 80 chr3:184869895-184869975 1.0000 80 chr7:130420223-130420303 1.0000 80 chr6:7543792-7543872 1.0000 80 chr2:23612124-23612204 1.0000 80 chr1:43613510-43613590 1.0000 80 chr2:121010371-121010451 1.0000 80 chr4:185913123-185913203 1.0000 80 chr7:73983919-73983999 1.0000 80 chr7:36404263-36404343 1.0000 80 chr10:29228943-29229023 1.0000 80 chr12:4376411-4376491 1.0000 80 chr3:129418184-129418264 1.0000 80 chr10:17514978-17515058 1.0000 80 chr2:196933159-196933239 1.0000 80 chr17:46825564-46825644 1.0000 80 chr15:90728478-90728558 1.0000 80 chr3:14316127-14316207 1.0000 80 chr19:43952486-43952566 1.0000 80 chr17:57643509-57643589 1.0000 80 chr14:71786920-71787000 1.0000 80 chr16:57980529-57980609 1.0000 80 chr5:154237392-154237472 1.0000 80 chr12:7009210-7009290 1.0000 80 chr10:76349135-76349215 1.0000 80 chr2:175870144-175870224 1.0000 80 chr17:46102469-46102549 1.0000 80 chr6:43478073-43478153 1.0000 80 chr11:44564032-44564112 1.0000 80 chr10:12171514-12171594 1.0000 80 chr1:90431115-90431195 1.0000 80 chr19:46919811-46919891 1.0000 80 chr21:37602778-37602858 1.0000 80 chr7:130406809-130406889 1.0000 80 chr1:155164670-155164750 1.0000 80 chr17:26794684-26794764 1.0000 80 chr3:39222389-39222469 1.0000 80 chr22:50710263-50710343 1.0000 80 chr2:158124230-158124310 1.0000 80 chr10:103348021-10334810 1.0000 80 chr7:1577742-1577822 1.0000 80 chr1:40157363-40157443 1.0000 80 chr20:57482988-57483068 1.0000 80 chr9:96846607-96846687 1.0000 80 chr3:150064026-150064106 1.0000 80 chr17:41132490-41132570 1.0000 80 chr9:3525842-3525922 1.0000 80 chr2:66796509-66796589 1.0000 80 chr19:59084188-59084268 1.0000 80 chr4:99583403-99583483 1.0000 80 chr19:46296104-46296184 1.0000 80 chr15:96873820-96873900 1.0000 80 chr8:57121488-57121568 1.0000 80 chr10:134124962-13412504 1.0000 80 chrX:1033501-1033581 1.0000 80 chr1:76457372-76457452 1.0000 80 chr11:27384823-27384903 1.0000 80 chr21:44847193-44847273 1.0000 80 chr11:64902595-64902675 1.0000 80 chr7:101398291-101398371 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_BMI1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/BMI1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.243 C 0.265 G 0.26 T 0.232 Background letter frequencies (from file dataset with add-one prior applied): A 0.243 C 0.264 G 0.26 T 0.232 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CATGGCAA MEME-1 width = 8 sites = 180 llr = 1402 E-value = 1.2e-185 ******************************************************************************** -------------------------------------------------------------------------------- Motif CATGGCAA MEME-1 Description -------------------------------------------------------------------------------- Simplified A :9:21:8a pos.-specific C a1:::8:: probability G ::189:1: matrix T :19::11: bits 2.1 1.9 1.7 * * 1.5 *** * * Relative 1.3 ***** ** Entropy 1.1 ******** (11.2 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CATGGCAA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGGCAA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrX:1033501-1033581 69 1.57e-05 gccccctttc catggcaa cgac chr15:96873820-96873900 36 1.57e-05 GCGCCGTCGC CATGGCAA CGTGCGCTAA chr7:1577742-1577822 56 1.57e-05 CCAAGGTCGC CATGGCAA CTATCGGAGG chr2:158124230-158124310 32 1.57e-05 TTACATTTAC CATGGCAA CCACAGCCGC chr19:46919811-46919891 53 1.57e-05 CGGCGGTCTC CATGGCAA CCACGGGACG chr1:90431115-90431195 50 1.57e-05 tttttgttgt catggcaa ccagcaatat chr10:12171514-12171594 46 1.57e-05 CCGTGGTCAC CATGGCAA CGCAGCGGAC chr6:43478073-43478153 33 1.57e-05 GGCGAGTTCC CATGGCAA CGGCCGCGTC chr2:175870144-175870224 26 1.57e-05 AGTGCGTTCC CATGGCAA CGGGCGCGCG chr19:43952486-43952566 67 1.57e-05 ttaccgttgc catggcaa cacctg chr3:14316127-14316207 59 1.57e-05 tgggtgttgc catggcaa tggtgaactg chr10:17514978-17515058 34 1.57e-05 ttacaaatgc catggcaa caacccagga chr3:129418184-129418264 41 1.57e-05 ttacaaatgc catggcaa cgtccagaag chr19:17854832-17854912 56 1.57e-05 tgcatgttgt catggcaa tggtaaactg chr18:12904071-12904151 13 1.57e-05 tttacaatgc catggcaa cgtcaggaag chr22:38453088-38453168 22 1.57e-05 CTTTCGTTGC CATGGCAA ccgccgggcc chr1:21716394-21716474 18 1.57e-05 ttacaaatgc catggcaa cgtctagaaa chr18:3013516-3013596 24 1.57e-05 TTCCGGTCCC CATGGCAA CCCTGCGGCA chr19:50554342-50554422 61 1.57e-05 TGTCTTTCTC CATGGCAA CTGTCTACGC chr9:130856745-130856825 29 1.57e-05 ACTAGGCTGT CATGGCAA CCTGATCATC chr12:76486317-76486397 52 1.57e-05 cacccctttc catggcaa tgacctggaa chr1:155804460-155804540 51 1.57e-05 ttacaaatgc catggcaa cccccagatg chr7:617674-617754 20 1.57e-05 cgggtgttgt catggcaa cggtaaactg chr2:64632073-64632153 56 1.57e-05 cacccttttc catggcaa tgacccaatg chr19:56098763-56098843 41 1.57e-05 CGGCCATCTC CATGGCAA CGCTGGCGCC chr17:49205584-49205664 50 1.57e-05 tgggtgttgc catggcaa tggtaaactg chr17:7117995-7118075 43 1.57e-05 CGCCGGTTAC CATGGCAA CGGCGGCAGC chr11:65951332-65951412 56 1.57e-05 tgggtgttgc catggcaa tggtaaacta chr19:28887377-28887457 58 1.57e-05 agtccctttc catggcaa tgatctgatg chr20:34652621-34652701 24 1.57e-05 CCGCGGCTGC CATGGCAA CGCCCGGAAG chr1:207752863-207752943 50 1.57e-05 ttacaaatgc catggcaa cgacctagaa chr6:36313997-36314077 24 1.57e-05 ttaccattgc catggcaa cacccagaag chr12:116944238-11694431 50 1.57e-05 cgcccctttc catggcaa cgacccaatg chr7:45129090-45129170 42 1.57e-05 CTCCTGTCTC CATGGCAA CCAGGGATGG chr3:138048641-138048721 47 1.57e-05 CCGCGGTCGT CATGGCAA CCTGGCCCCC chr1:151682829-151682909 16 1.57e-05 GAATGCGCAC CATGGCAA CCGCCCACTC chr22:39615565-39615645 52 1.57e-05 tgcctctttc catggcaa cgacccatga chr6:25988235-25988315 56 1.57e-05 ttttcgttgc catggcaa caacaggaca chr10:103157018-10315709 58 1.57e-05 ATCCTGTTGT CATGGCAA CCACAGTTGT chr12:9066910-9066990 62 1.57e-05 GCTGCGTCGC CATGGCAA CGGGCGCCGG chr7:32945097-32945177 35 1.57e-05 tgggtgttgc catggcaa tggtaaactc chr20:5639682-5639762 41 1.57e-05 GTCTGGTTCC CATGGCAA CAGCCCTGAA chr16:29675603-29675683 10 1.57e-05 CCCTGTTAC CATGGCAA CTGACTCTCT chr2:11531853-11531933 51 1.57e-05 TTGTTGTTGC CATGGCAA CCATCTAAAC chr19:39536863-39536943 28 1.57e-05 ttacaaatgc catggcaa cgacctggaa chr9:129482090-129482170 55 1.57e-05 CTTGGGTTTC CATGGCAA CCAGTCACCC chr19:14411305-14411385 53 1.57e-05 cgcccctttc catggcaa ctacccaacc chr19:17012772-17012852 15 1.57e-05 CTGCGAGTGT CATGGCAA CCACTCACCC chr1:26459157-26459237 49 1.57e-05 cacccctttc catggcaa tgacctgacg chr7:100104305-100104385 55 1.57e-05 tgggtgttgt catggcaa cggtaaactg chr20:1404636-1404716 63 1.57e-05 cacccctttc catggcaa caactcggca chr17:47753699-47753779 41 1.57e-05 TAACTGTAAC CATGGCAA CAGGAAACAG chr1:20335073-20335153 57 1.57e-05 caggtgttgc catggcaa tggtaaactg chr1:42814313-42814393 12 1.57e-05 ATTTTGTCAC CATGGCAA CTGGTCATTG chr3:156227740-156227820 61 1.57e-05 AATTTTAATT CATGGCAA CATGAATCTC chr20:42072889-42072969 55 1.57e-05 ttactgttgc catggcaa cacccggacg chr20:30085820-30085900 10 1.57e-05 CACCATAGT CATGGCAA CAGTCTCCTT chr7:137846440-137846520 35 1.57e-05 CCTCGGTTAC CATGGCAA CCAGCTACCC chr17:58239103-58239183 31 1.57e-05 TTGCTGTTGC CATGGCAA CCGCAGGCCG chr1:207884842-207884922 30 1.57e-05 ttacaaatgc catggcaa cgatctggaa chr10:43818326-43818406 11 1.57e-05 TTACCGTCAC CATGGCAA CAGCGCGTCC chr11:62537436-62537516 50 1.57e-05 GTGGGGTTGC CATGGCAA CCACAGTCGC chr7:100087583-100087663 45 1.57e-05 CAGCTGTTAC CATGGCAA CCCATCCAGA chr19:3271065-3271145 54 1.57e-05 TCAGCGTTGC CATGGCAA CCCCATCCTC chr3:179615939-179616019 57 1.57e-05 CCTTCATCAC CATGGCAA CAGCCTTATC chr2:66796509-66796589 43 3.03e-05 AGTGGGTTGT CATAGCAA CAGACTGATT chr11:44564032-44564112 59 3.03e-05 tcgtcatcac catagcaa ccatctccat chr14:71786920-71787000 25 3.03e-05 TTGCCGTCGT CATAGCAA CCAGAAGTTC chr1:208267816-208267896 14 3.03e-05 TCTGTGTTGC CATAGCAA TACATCTTTG chr21:43916464-43916544 22 3.03e-05 TGCGTACTGT CATAGCAA CGGGAAGGGC chr12:109548827-10954890 61 3.03e-05 CCAGGGTTCC CATAGCAA CCACCGTCTG chr1:15735938-15736018 38 3.03e-05 Gagtcgtttc catagcaa ccgacagggt chr16:759701-759781 17 3.03e-05 CAGCCATCAC CATAGCAA CACGCGTCGC chr20:11873038-11873118 34 3.03e-05 TGCGGGTTCC CATAGCAA CGAGTCCTCC chr9:35114226-35114306 64 3.03e-05 GCAGTGTTGC CATAGCAA TCAGCTCCT chr10:3916061-3916141 47 3.03e-05 GGTCGGTTTC CATAGCAA CACTCTTGGT chr12:54653403-54653483 30 3.03e-05 AGTCCGTTGC CATAGCAA CTGGCAGCAG chr3:167098101-167098181 35 3.03e-05 CCTCGGTACC CATAGCAA CCAGAAAGCT chr1:21525610-21525690 10 3.03e-05 gaaggtaac catagcaa caatgaaggt chr2:241771942-241772022 56 3.03e-05 GCGCCGTTGC CATAGCAA CGGCGGGTGG chr2:198799163-198799243 33 3.03e-05 TTCTTGTAAC CATAGCAA CCAAGACAGA chr19:1860182-1860262 46 3.03e-05 TCTCCGTAAC CATAGCAA CGGCGTCAAC chr20:57482988-57483068 51 4.41e-05 GTTCTGTTGC CATGGTAA CATGCTGGAG chr7:73983919-73983999 34 4.41e-05 TTCAGGTTAC CATGGTAA CCATATTTCC chr19:47250073-47250153 54 4.41e-05 GGTTGGTTGT CATGGTAA CCCTTCCCCA chr7:99699532-99699612 56 4.41e-05 CCCCGGTTGT CATGGTAA CCAGTGGCGG chr8:26482876-26482956 50 4.41e-05 GGAGGGTTAC CATGGTAA CTGTTGCCTG chr22:32360094-32360174 63 4.41e-05 ATCTGATCAC CATGGTAA CCCTCCAGGA chr1:201643320-201643400 16 4.41e-05 GTTAAGTCGC CATGGTAA CCCTCTGGCT chr19:47972051-47972131 52 4.41e-05 CTCATGTTGC CATGGTAA CCCAGTGGCT chr19:42500248-42500328 13 4.41e-05 CCTTTGTTGC CATGGTAA CAGGGAGCTG chr8:30515831-30515911 34 5.88e-05 CTGGGGCCTC CATGACAA CGAGGGAAGG chr17:46226864-46226944 57 5.88e-05 TAGGCGTTTC CATGACAA CCGCTTATAG chr11:34673287-34673367 37 5.88e-05 CTCAGATCTC CATGACAA CCACCAGTCA chrX:133938031-133938111 41 5.88e-05 TCAAGGTTGT CATGACAA CTGGTAAAAT chr17:38375048-38375128 28 5.88e-05 CCTCTGTTGC CATGACAA CCGGAGCTTG chr19:46981762-46981842 29 5.88e-05 CAGTGGTTTC CATGACAA CACGATGTGC chr8:125622624-125622704 45 5.88e-05 GATCTGTTGC CATGACAA CAATCACTTG chr1:201622493-201622573 33 5.88e-05 AAGCGGTTGT CATGACAA CAGTTAGGCC chr19:51243474-51243554 53 5.88e-05 ttcccgttgc catgacaa caccccgacg chr11:27384823-27384903 27 7.56e-05 CCCGCGTTGC CATGGCGA CGCGTGGAGG chr22:50710263-50710343 22 7.56e-05 GTCGGGTTCC CATGGCGA CCGGCCCCGC chr1:155164670-155164750 57 7.56e-05 CACGCGTCAC CATGGCGA CGGCTCCGCG chr12:7009210-7009290 44 7.56e-05 ttaccattgc catggcga cacccagaag chr1:24345454-24345534 46 7.56e-05 GACAGGTTGC CATGGCGA CCTCCCCACT chr17:74137366-74137446 20 7.56e-05 CTCCTGCTGC CATGGCGA CGCTCCGCCC chr17:64188279-64188359 27 7.56e-05 GTGCGGTTGC CATGGCGA CGTTCCCGGC chr10:29228943-29229023 26 9.05e-05 TTATGGTTGT CTTGGCAA CCAGCTTTGC chr7:17274216-17274296 26 9.05e-05 CCCAAGTTCC CTTGGCAA CAAGTAGAGT chr1:159869921-159870001 45 9.05e-05 GACGCGTTAC CTTGGCAA CCACTAGCCC chr9:96846607-96846687 70 1.38e-04 TGTTTGTCGC CATGGAAA CCA chr10:76349135-76349215 60 1.38e-04 CAGCAGTTGC CATGGAAA CTTGGCAGTC chr19:18263385-18263465 56 1.38e-04 TCTGGGTTGC CATGGAAA CTCCTTCAAC chr16:30959615-30959695 29 1.38e-04 TCCTGGTTGC CATGGAAA TAGCAGCCAA chr19:11484375-11484455 59 1.38e-04 ACAAGGTTGC CAGGGCAA CACAGGCGTG chr5:154237392-154237472 23 1.68e-04 GGCCAGTTGC TATGGCAA TGTTCCTCGC chr19:9945425-9945505 58 1.68e-04 ACTGCATTGC TATGGCAA CAGCAGAGGC chr17:7117370-7117450 10 1.68e-04 TCTCTGTTG CCTGGCAA CGCAGCAATC chr9:3525842-3525922 57 1.98e-04 GCTTGATTCA CAAGGCAA CGGTTGCTAT chr5:88025335-88025415 18 1.98e-04 CAGCTGTTGC CATAGTAA CCCATTACAT chr2:232469502-232469582 70 1.98e-04 GTTTGGTTCC CAAGGCAA CTG chr7:157100714-157100794 71 1.98e-04 tgtaaactgt caaggcaa tg chr17:17566783-17566863 39 2.11e-04 CTTGCGTCGC CATAACAA CAGACGGCTC chr7:16503299-16503379 18 2.11e-04 GTATGGTTGC CATAACAA CTTGGCTACA chr17:41132490-41132570 56 2.41e-04 GCGCCGTTGC CATGGCAG CAGGGGGGCG chr10:103348021-10334810 35 2.41e-04 GAACGGTTGC CATGGCAG CGGCTGGGCG chr15:90728478-90728558 22 2.41e-04 AGCCTGTTGC CATGGCAG CGCAGGAGGC chr1:12719160-12719240 59 2.72e-04 GACCTGTTGT CATGGGAa cagaacccag chr7:36404263-36404343 8 3.33e-04 AGAAGAA CATGGCCA TCTCAGATAT chr1:100817825-100817905 26 3.33e-04 GCAACAAAGC CTTAGCAA CCGGCTCCTA chr11:76758786-76758866 42 3.33e-04 cggtcgttgc catggcat ttgtaaactg chr19:55850574-55850654 61 3.46e-04 GTTTCGTCGC CTTGGTAA CCGCAGGCCT chr3:129033833-129033913 14 3.62e-04 GGCCAGTAAC CATGACGA CGGCCGTTGC chr5:149893451-149893531 55 3.62e-04 ATGGCGTCTC CATGACGA CCAGAGCATC chr4:47688435-47688515 22 4.20e-04 TAGCGATCAC CTTGACAA CGGTATTTTA chr11:15988797-15988877 50 4.20e-04 AGCACAGTAC CTTGACAA CAGAGTTGCA chr8:22858358-22858438 56 4.20e-04 CTGTTGTTTC CTTGACAA CCAGACTAGG chr17:57643509-57643589 11 4.77e-04 AGCCAGTTTC CATGGTTA CCCACCACTT chr1:202318488-202318568 36 4.77e-04 CTTGTGTTGT CATGGTTA CTGGTGATTT chr11:118528049-11852812 52 4.77e-04 GCTTCATTGC CATGGTTA CATACTAATT chr5:43193865-43193945 46 4.77e-04 TTCTGGTTGT CATGGTTA CTGAAGAAGT chr11:125387190-12538727 46 4.77e-04 ATAAGGTTCC CATGGTTA CTAGGAAGAG chr6:53357777-53357857 42 4.77e-04 AATTTCGTTT TATAGCAA ATGCGCTCTG chr19:15334361-15334441 30 4.77e-04 TTTCCGTCGC CCTAGCAA CCGTCAGCGG chr20:5695346-5695426 42 4.77e-04 ACATTGTTAC CATGGTTA CCAGGGAAGT chr9:129486225-129486305 71 4.77e-04 TCATCGTTAC CATGGTTA CA chr1:39564347-39564427 18 5.04e-04 GGCCAGTTGC TATGGTAA CCCAGATGGC chr7:130406809-130406889 42 5.48e-04 AGATAAAAGC CATGACTA CACATGACCC chr16:58529163-58529243 47 5.48e-04 CAGCTGTTGC CAGGACAA CCCTGTCCTC chr17:7108225-7108305 59 5.48e-04 GCCCTGTCGT CAGGACAA CAGGGGGGTG chr19:55690776-55690856 61 5.48e-04 GGGTTGTTGC CAGGACAA CGGGCGGGGC chr3:39222389-39222469 68 6.08e-04 TCATCGTCAC CTTGGCGA CGGCC chr19:13842452-13842532 40 6.08e-04 CCCCGGTCGC CCTGACAA CAGCGCCGGC chr2:219221525-219221605 38 7.00e-04 CTCTGGTTGC CATGGAGA CAGCTGGACA chr18:20773854-20773934 58 7.00e-04 ACCTCCCAGG CATAGCAG GTCAAGTTGA chr21:44847193-44847273 57 7.93e-04 AGGCCGTTGC CCTGGCGA CCGCGGGCCG chr2:74648739-74648819 18 7.93e-04 TAACAGTCGC CTGGGCAA CCACGGGCTC chr16:81554877-81554957 12 7.93e-04 GCACGGTTGC CATGGTAG CAGCAGGATG chr19:6066794-6066874 68 7.93e-04 GAGCCTGTTG CTGGGCAA CCGGG chr1:33546612-33546692 53 9.44e-04 ACCCGGTTGC CAGGGCTA CGGCCAAGCG chr8:27696610-27696690 54 9.44e-04 cccgggttgc catagcat ttgtaaaccg chr15:72598732-72598812 57 9.44e-04 TTCCTGTTAC CATAGCCA CAAGTGCTAC chr5:176884805-176884885 61 9.44e-04 CAGTGGTTGC CAGGGAAA CAAGGATGCC chr8:57119854-57119934 63 9.44e-04 CCAAAATGTA CATAGTGA CAATCAGGAT chr19:46296104-46296184 11 1.09e-03 GGGTCGTCGC CCGGGCAA CGCCTCTTCG chr19:59084188-59084268 20 1.09e-03 CAGACGACGC CTAGGCAA CCGGGGGCGG chr1:40157363-40157443 50 1.09e-03 TCACCGTTGC TATGGAAA CGGGAGAACC chr17:46102469-46102549 21 1.09e-03 TGCAGGTTGC TAGGGCAA CGTCCTGTCG chr12:6716690-6716770 14 1.09e-03 CCCAGGTCTC CCGGGCAA CCCCCGCCCC chr5:108804597-108804677 38 1.09e-03 CCAACGTTGT CATGGTCA CTGGCTGCAG chr7:100273249-100273329 45 1.09e-03 TGACGGTTGC CTAGGCAA CCCCACGAAC chr17:46826608-46826688 51 1.09e-03 AATTTGTTTT CATGGTAT TTTGCTAAAA chr17:9479909-9479989 40 1.14e-03 CGTCCGTTAC CATAACGA CCAGAAGACG chr7:101397802-101397882 60 1.14e-03 GAGATTCGTT TCTGGCAA GGTTCCTTTC chr1:110163572-110163652 63 1.14e-03 GCCTAGACAA CATGAGAA ATCGTGGCCA chr3:59035848-59035928 39 1.35e-03 GTAGCGTTGC CCAGGCAA CCGCGGGACT chr12:96883287-96883367 52 1.35e-03 GAGACCGTCG CCAGGCAA CCGCGTGTAC chr19:720204-720284 31 1.41e-03 TCGGCGTTGC CATGGGGA CGGCGCGGTT chr7:155414274-155414354 50 1.41e-03 GAAAAAGCAC CATAAAAA GAGAATTCGT chr6:157274853-157274933 54 2.15e-03 TTAGCGTTGC TATGGTGA CAGGGTGGGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGGCAA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrX:1033501-1033581 1.6e-05 68_[+1]_4 chr15:96873820-96873900 1.6e-05 35_[+1]_37 chr7:1577742-1577822 1.6e-05 55_[+1]_17 chr2:158124230-158124310 1.6e-05 31_[+1]_41 chr19:46919811-46919891 1.6e-05 52_[+1]_20 chr1:90431115-90431195 1.6e-05 49_[+1]_23 chr10:12171514-12171594 1.6e-05 45_[+1]_27 chr6:43478073-43478153 1.6e-05 32_[+1]_40 chr2:175870144-175870224 1.6e-05 25_[+1]_47 chr19:43952486-43952566 1.6e-05 66_[+1]_6 chr3:14316127-14316207 1.6e-05 58_[+1]_14 chr10:17514978-17515058 1.6e-05 33_[+1]_39 chr3:129418184-129418264 1.6e-05 40_[+1]_32 chr19:17854832-17854912 1.6e-05 55_[+1]_17 chr18:12904071-12904151 1.6e-05 12_[+1]_60 chr22:38453088-38453168 1.6e-05 21_[+1]_51 chr1:21716394-21716474 1.6e-05 17_[+1]_55 chr18:3013516-3013596 1.6e-05 23_[+1]_49 chr19:50554342-50554422 1.6e-05 60_[+1]_12 chr9:130856745-130856825 1.6e-05 28_[+1]_44 chr12:76486317-76486397 1.6e-05 51_[+1]_21 chr1:155804460-155804540 1.6e-05 50_[+1]_22 chr7:617674-617754 1.6e-05 19_[+1]_53 chr2:64632073-64632153 1.6e-05 55_[+1]_17 chr19:56098763-56098843 1.6e-05 40_[+1]_32 chr17:49205584-49205664 1.6e-05 49_[+1]_23 chr17:7117995-7118075 1.6e-05 42_[+1]_30 chr11:65951332-65951412 1.6e-05 55_[+1]_17 chr19:28887377-28887457 1.6e-05 57_[+1]_15 chr20:34652621-34652701 1.6e-05 23_[+1]_49 chr1:207752863-207752943 1.6e-05 49_[+1]_23 chr6:36313997-36314077 1.6e-05 23_[+1]_49 chr12:116944238-11694431 1.6e-05 49_[+1]_23 chr7:45129090-45129170 1.6e-05 41_[+1]_31 chr3:138048641-138048721 1.6e-05 46_[+1]_26 chr1:151682829-151682909 1.6e-05 15_[+1]_57 chr22:39615565-39615645 1.6e-05 51_[+1]_21 chr6:25988235-25988315 1.6e-05 55_[+1]_17 chr10:103157018-10315709 1.6e-05 57_[+1]_15 chr12:9066910-9066990 1.6e-05 61_[+1]_11 chr7:32945097-32945177 1.6e-05 34_[+1]_38 chr20:5639682-5639762 1.6e-05 40_[+1]_32 chr16:29675603-29675683 1.6e-05 9_[+1]_63 chr2:11531853-11531933 1.6e-05 50_[+1]_22 chr19:39536863-39536943 1.6e-05 27_[+1]_45 chr9:129482090-129482170 1.6e-05 54_[+1]_18 chr19:14411305-14411385 1.6e-05 52_[+1]_20 chr19:17012772-17012852 1.6e-05 14_[+1]_58 chr1:26459157-26459237 1.6e-05 48_[+1]_24 chr7:100104305-100104385 1.6e-05 54_[+1]_18 chr20:1404636-1404716 1.6e-05 62_[+1]_10 chr17:47753699-47753779 1.6e-05 40_[+1]_32 chr1:20335073-20335153 1.6e-05 56_[+1]_16 chr1:42814313-42814393 1.6e-05 11_[+1]_61 chr3:156227740-156227820 1.6e-05 60_[+1]_12 chr20:42072889-42072969 1.6e-05 54_[+1]_18 chr20:30085820-30085900 1.6e-05 9_[+1]_63 chr7:137846440-137846520 1.6e-05 34_[+1]_38 chr17:58239103-58239183 1.6e-05 30_[+1]_42 chr1:207884842-207884922 1.6e-05 29_[+1]_43 chr10:43818326-43818406 1.6e-05 10_[+1]_62 chr11:62537436-62537516 1.6e-05 49_[+1]_23 chr7:100087583-100087663 1.6e-05 44_[+1]_28 chr19:3271065-3271145 1.6e-05 53_[+1]_19 chr3:179615939-179616019 1.6e-05 56_[+1]_16 chr2:66796509-66796589 3e-05 42_[+1]_30 chr11:44564032-44564112 3e-05 58_[+1]_14 chr14:71786920-71787000 3e-05 24_[+1]_48 chr1:208267816-208267896 3e-05 13_[+1]_59 chr21:43916464-43916544 3e-05 21_[+1]_51 chr12:109548827-10954890 3e-05 60_[+1]_12 chr1:15735938-15736018 3e-05 37_[+1]_35 chr16:759701-759781 3e-05 16_[+1]_56 chr20:11873038-11873118 3e-05 33_[+1]_39 chr9:35114226-35114306 3e-05 63_[+1]_9 chr10:3916061-3916141 3e-05 46_[+1]_26 chr12:54653403-54653483 3e-05 29_[+1]_43 chr3:167098101-167098181 3e-05 34_[+1]_38 chr1:21525610-21525690 3e-05 9_[+1]_63 chr2:241771942-241772022 3e-05 55_[+1]_17 chr2:198799163-198799243 3e-05 32_[+1]_40 chr19:1860182-1860262 3e-05 45_[+1]_27 chr20:57482988-57483068 4.4e-05 50_[+1]_22 chr7:73983919-73983999 4.4e-05 33_[+1]_39 chr19:47250073-47250153 4.4e-05 53_[+1]_19 chr7:99699532-99699612 4.4e-05 55_[+1]_17 chr8:26482876-26482956 4.4e-05 49_[+1]_23 chr22:32360094-32360174 4.4e-05 62_[+1]_10 chr1:201643320-201643400 4.4e-05 15_[+1]_57 chr19:47972051-47972131 4.4e-05 51_[+1]_21 chr19:42500248-42500328 4.4e-05 12_[+1]_60 chr8:30515831-30515911 5.9e-05 33_[+1]_39 chr17:46226864-46226944 5.9e-05 56_[+1]_16 chr11:34673287-34673367 5.9e-05 36_[+1]_36 chrX:133938031-133938111 5.9e-05 40_[+1]_32 chr17:38375048-38375128 5.9e-05 27_[+1]_45 chr19:46981762-46981842 5.9e-05 28_[+1]_44 chr8:125622624-125622704 5.9e-05 44_[+1]_28 chr1:201622493-201622573 5.9e-05 32_[+1]_40 chr19:51243474-51243554 5.9e-05 52_[+1]_20 chr11:27384823-27384903 7.6e-05 26_[+1]_46 chr22:50710263-50710343 7.6e-05 21_[+1]_51 chr1:155164670-155164750 7.6e-05 56_[+1]_16 chr12:7009210-7009290 7.6e-05 43_[+1]_29 chr1:24345454-24345534 7.6e-05 45_[+1]_27 chr17:74137366-74137446 7.6e-05 19_[+1]_53 chr17:64188279-64188359 7.6e-05 26_[+1]_46 chr10:29228943-29229023 9.1e-05 25_[+1]_47 chr7:17274216-17274296 9.1e-05 25_[+1]_47 chr1:159869921-159870001 9.1e-05 44_[+1]_28 chr9:96846607-96846687 0.00014 69_[+1]_3 chr10:76349135-76349215 0.00014 59_[+1]_13 chr19:18263385-18263465 0.00014 55_[+1]_17 chr16:30959615-30959695 0.00014 28_[+1]_44 chr19:11484375-11484455 0.00014 58_[+1]_14 chr5:154237392-154237472 0.00017 22_[+1]_50 chr19:9945425-9945505 0.00017 57_[+1]_15 chr17:7117370-7117450 0.00017 9_[+1]_63 chr9:3525842-3525922 0.0002 56_[+1]_16 chr5:88025335-88025415 0.0002 17_[+1]_55 chr2:232469502-232469582 0.0002 69_[+1]_3 chr7:157100714-157100794 0.0002 70_[+1]_2 chr17:17566783-17566863 0.00021 38_[+1]_34 chr7:16503299-16503379 0.00021 17_[+1]_55 chr17:41132490-41132570 0.00024 55_[+1]_17 chr10:103348021-10334810 0.00024 34_[+1]_38 chr15:90728478-90728558 0.00024 21_[+1]_51 chr1:12719160-12719240 0.00027 58_[+1]_14 chr7:36404263-36404343 0.00033 7_[+1]_65 chr1:100817825-100817905 0.00033 25_[+1]_47 chr11:76758786-76758866 0.00033 41_[+1]_31 chr19:55850574-55850654 0.00035 60_[+1]_12 chr3:129033833-129033913 0.00036 13_[+1]_59 chr5:149893451-149893531 0.00036 54_[+1]_18 chr4:47688435-47688515 0.00042 21_[+1]_51 chr11:15988797-15988877 0.00042 49_[+1]_23 chr8:22858358-22858438 0.00042 55_[+1]_17 chr17:57643509-57643589 0.00048 10_[+1]_62 chr1:202318488-202318568 0.00048 35_[+1]_37 chr11:118528049-11852812 0.00048 51_[+1]_21 chr5:43193865-43193945 0.00048 45_[+1]_27 chr11:125387190-12538727 0.00048 45_[+1]_27 chr6:53357777-53357857 0.00048 41_[+1]_31 chr19:15334361-15334441 0.00048 29_[+1]_43 chr20:5695346-5695426 0.00048 41_[+1]_31 chr9:129486225-129486305 0.00048 70_[+1]_2 chr1:39564347-39564427 0.0005 17_[+1]_55 chr7:130406809-130406889 0.00055 41_[+1]_31 chr16:58529163-58529243 0.00055 46_[+1]_26 chr17:7108225-7108305 0.00055 58_[+1]_14 chr19:55690776-55690856 0.00055 60_[+1]_12 chr3:39222389-39222469 0.00061 67_[+1]_5 chr19:13842452-13842532 0.00061 39_[+1]_33 chr2:219221525-219221605 0.0007 37_[+1]_35 chr18:20773854-20773934 0.0007 57_[+1]_15 chr21:44847193-44847273 0.00079 56_[+1]_16 chr2:74648739-74648819 0.00079 17_[+1]_55 chr16:81554877-81554957 0.00079 11_[+1]_61 chr19:6066794-6066874 0.00079 67_[+1]_5 chr1:33546612-33546692 0.00094 52_[+1]_20 chr8:27696610-27696690 0.00094 53_[+1]_19 chr15:72598732-72598812 0.00094 56_[+1]_16 chr5:176884805-176884885 0.00094 60_[+1]_12 chr8:57119854-57119934 0.00094 62_[+1]_10 chr19:46296104-46296184 0.0011 10_[+1]_62 chr19:59084188-59084268 0.0011 19_[+1]_53 chr1:40157363-40157443 0.0011 49_[+1]_23 chr17:46102469-46102549 0.0011 20_[+1]_52 chr12:6716690-6716770 0.0011 13_[+1]_59 chr5:108804597-108804677 0.0011 37_[+1]_35 chr7:100273249-100273329 0.0011 44_[+1]_28 chr17:46826608-46826688 0.0011 50_[+1]_22 chr17:9479909-9479989 0.0011 39_[+1]_33 chr7:101397802-101397882 0.0011 59_[+1]_13 chr1:110163572-110163652 0.0011 62_[+1]_10 chr3:59035848-59035928 0.0014 38_[+1]_34 chr12:96883287-96883367 0.0014 51_[+1]_21 chr19:720204-720284 0.0014 30_[+1]_42 chr7:155414274-155414354 0.0014 49_[+1]_23 chr6:157274853-157274933 0.0021 53_[+1]_19 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGGCAA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CATGGCAA width=8 seqs=180 chrX:1033501-1033581 ( 69) CATGGCAA 1 chr15:96873820-96873900 ( 36) CATGGCAA 1 chr7:1577742-1577822 ( 56) CATGGCAA 1 chr2:158124230-158124310 ( 32) CATGGCAA 1 chr19:46919811-46919891 ( 53) CATGGCAA 1 chr1:90431115-90431195 ( 50) CATGGCAA 1 chr10:12171514-12171594 ( 46) CATGGCAA 1 chr6:43478073-43478153 ( 33) CATGGCAA 1 chr2:175870144-175870224 ( 26) CATGGCAA 1 chr19:43952486-43952566 ( 67) CATGGCAA 1 chr3:14316127-14316207 ( 59) CATGGCAA 1 chr10:17514978-17515058 ( 34) CATGGCAA 1 chr3:129418184-129418264 ( 41) CATGGCAA 1 chr19:17854832-17854912 ( 56) CATGGCAA 1 chr18:12904071-12904151 ( 13) CATGGCAA 1 chr22:38453088-38453168 ( 22) CATGGCAA 1 chr1:21716394-21716474 ( 18) CATGGCAA 1 chr18:3013516-3013596 ( 24) CATGGCAA 1 chr19:50554342-50554422 ( 61) CATGGCAA 1 chr9:130856745-130856825 ( 29) CATGGCAA 1 chr12:76486317-76486397 ( 52) CATGGCAA 1 chr1:155804460-155804540 ( 51) CATGGCAA 1 chr7:617674-617754 ( 20) CATGGCAA 1 chr2:64632073-64632153 ( 56) CATGGCAA 1 chr19:56098763-56098843 ( 41) CATGGCAA 1 chr17:49205584-49205664 ( 50) CATGGCAA 1 chr17:7117995-7118075 ( 43) CATGGCAA 1 chr11:65951332-65951412 ( 56) CATGGCAA 1 chr19:28887377-28887457 ( 58) CATGGCAA 1 chr20:34652621-34652701 ( 24) CATGGCAA 1 chr1:207752863-207752943 ( 50) CATGGCAA 1 chr6:36313997-36314077 ( 24) CATGGCAA 1 chr12:116944238-11694431 ( 50) CATGGCAA 1 chr7:45129090-45129170 ( 42) CATGGCAA 1 chr3:138048641-138048721 ( 47) CATGGCAA 1 chr1:151682829-151682909 ( 16) CATGGCAA 1 chr22:39615565-39615645 ( 52) CATGGCAA 1 chr6:25988235-25988315 ( 56) CATGGCAA 1 chr10:103157018-10315709 ( 58) CATGGCAA 1 chr12:9066910-9066990 ( 62) CATGGCAA 1 chr7:32945097-32945177 ( 35) CATGGCAA 1 chr20:5639682-5639762 ( 41) CATGGCAA 1 chr16:29675603-29675683 ( 10) CATGGCAA 1 chr2:11531853-11531933 ( 51) CATGGCAA 1 chr19:39536863-39536943 ( 28) CATGGCAA 1 chr9:129482090-129482170 ( 55) CATGGCAA 1 chr19:14411305-14411385 ( 53) CATGGCAA 1 chr19:17012772-17012852 ( 15) CATGGCAA 1 chr1:26459157-26459237 ( 49) CATGGCAA 1 chr7:100104305-100104385 ( 55) CATGGCAA 1 chr20:1404636-1404716 ( 63) CATGGCAA 1 chr17:47753699-47753779 ( 41) CATGGCAA 1 chr1:20335073-20335153 ( 57) CATGGCAA 1 chr1:42814313-42814393 ( 12) CATGGCAA 1 chr3:156227740-156227820 ( 61) CATGGCAA 1 chr20:42072889-42072969 ( 55) CATGGCAA 1 chr20:30085820-30085900 ( 10) CATGGCAA 1 chr7:137846440-137846520 ( 35) CATGGCAA 1 chr17:58239103-58239183 ( 31) CATGGCAA 1 chr1:207884842-207884922 ( 30) CATGGCAA 1 chr10:43818326-43818406 ( 11) CATGGCAA 1 chr11:62537436-62537516 ( 50) CATGGCAA 1 chr7:100087583-100087663 ( 45) CATGGCAA 1 chr19:3271065-3271145 ( 54) CATGGCAA 1 chr3:179615939-179616019 ( 57) CATGGCAA 1 chr2:66796509-66796589 ( 43) CATAGCAA 1 chr11:44564032-44564112 ( 59) CATAGCAA 1 chr14:71786920-71787000 ( 25) CATAGCAA 1 chr1:208267816-208267896 ( 14) CATAGCAA 1 chr21:43916464-43916544 ( 22) CATAGCAA 1 chr12:109548827-10954890 ( 61) CATAGCAA 1 chr1:15735938-15736018 ( 38) CATAGCAA 1 chr16:759701-759781 ( 17) CATAGCAA 1 chr20:11873038-11873118 ( 34) CATAGCAA 1 chr9:35114226-35114306 ( 64) CATAGCAA 1 chr10:3916061-3916141 ( 47) CATAGCAA 1 chr12:54653403-54653483 ( 30) CATAGCAA 1 chr3:167098101-167098181 ( 35) CATAGCAA 1 chr1:21525610-21525690 ( 10) CATAGCAA 1 chr2:241771942-241772022 ( 56) CATAGCAA 1 chr2:198799163-198799243 ( 33) CATAGCAA 1 chr19:1860182-1860262 ( 46) CATAGCAA 1 chr20:57482988-57483068 ( 51) CATGGTAA 1 chr7:73983919-73983999 ( 34) CATGGTAA 1 chr19:47250073-47250153 ( 54) CATGGTAA 1 chr7:99699532-99699612 ( 56) CATGGTAA 1 chr8:26482876-26482956 ( 50) CATGGTAA 1 chr22:32360094-32360174 ( 63) CATGGTAA 1 chr1:201643320-201643400 ( 16) CATGGTAA 1 chr19:47972051-47972131 ( 52) CATGGTAA 1 chr19:42500248-42500328 ( 13) CATGGTAA 1 chr8:30515831-30515911 ( 34) CATGACAA 1 chr17:46226864-46226944 ( 57) CATGACAA 1 chr11:34673287-34673367 ( 37) CATGACAA 1 chrX:133938031-133938111 ( 41) CATGACAA 1 chr17:38375048-38375128 ( 28) CATGACAA 1 chr19:46981762-46981842 ( 29) CATGACAA 1 chr8:125622624-125622704 ( 45) CATGACAA 1 chr1:201622493-201622573 ( 33) CATGACAA 1 chr19:51243474-51243554 ( 53) CATGACAA 1 chr11:27384823-27384903 ( 27) CATGGCGA 1 chr22:50710263-50710343 ( 22) CATGGCGA 1 chr1:155164670-155164750 ( 57) CATGGCGA 1 chr12:7009210-7009290 ( 44) CATGGCGA 1 chr1:24345454-24345534 ( 46) CATGGCGA 1 chr17:74137366-74137446 ( 20) CATGGCGA 1 chr17:64188279-64188359 ( 27) CATGGCGA 1 chr10:29228943-29229023 ( 26) CTTGGCAA 1 chr7:17274216-17274296 ( 26) CTTGGCAA 1 chr1:159869921-159870001 ( 45) CTTGGCAA 1 chr9:96846607-96846687 ( 70) CATGGAAA 1 chr10:76349135-76349215 ( 60) CATGGAAA 1 chr19:18263385-18263465 ( 56) CATGGAAA 1 chr16:30959615-30959695 ( 29) CATGGAAA 1 chr19:11484375-11484455 ( 59) CAGGGCAA 1 chr5:154237392-154237472 ( 23) TATGGCAA 1 chr19:9945425-9945505 ( 58) TATGGCAA 1 chr17:7117370-7117450 ( 10) CCTGGCAA 1 chr9:3525842-3525922 ( 57) CAAGGCAA 1 chr5:88025335-88025415 ( 18) CATAGTAA 1 chr2:232469502-232469582 ( 70) CAAGGCAA 1 chr7:157100714-157100794 ( 71) CAAGGCAA 1 chr17:17566783-17566863 ( 39) CATAACAA 1 chr7:16503299-16503379 ( 18) CATAACAA 1 chr17:41132490-41132570 ( 56) CATGGCAG 1 chr10:103348021-10334810 ( 35) CATGGCAG 1 chr15:90728478-90728558 ( 22) CATGGCAG 1 chr1:12719160-12719240 ( 59) CATGGGAA 1 chr7:36404263-36404343 ( 8) CATGGCCA 1 chr1:100817825-100817905 ( 26) CTTAGCAA 1 chr11:76758786-76758866 ( 42) CATGGCAT 1 chr19:55850574-55850654 ( 61) CTTGGTAA 1 chr3:129033833-129033913 ( 14) CATGACGA 1 chr5:149893451-149893531 ( 55) CATGACGA 1 chr4:47688435-47688515 ( 22) CTTGACAA 1 chr11:15988797-15988877 ( 50) CTTGACAA 1 chr8:22858358-22858438 ( 56) CTTGACAA 1 chr17:57643509-57643589 ( 11) CATGGTTA 1 chr1:202318488-202318568 ( 36) CATGGTTA 1 chr11:118528049-11852812 ( 52) CATGGTTA 1 chr5:43193865-43193945 ( 46) CATGGTTA 1 chr11:125387190-12538727 ( 46) CATGGTTA 1 chr6:53357777-53357857 ( 42) TATAGCAA 1 chr19:15334361-15334441 ( 30) CCTAGCAA 1 chr20:5695346-5695426 ( 42) CATGGTTA 1 chr9:129486225-129486305 ( 71) CATGGTTA 1 chr1:39564347-39564427 ( 18) TATGGTAA 1 chr7:130406809-130406889 ( 42) CATGACTA 1 chr16:58529163-58529243 ( 47) CAGGACAA 1 chr17:7108225-7108305 ( 59) CAGGACAA 1 chr19:55690776-55690856 ( 61) CAGGACAA 1 chr3:39222389-39222469 ( 68) CTTGGCGA 1 chr19:13842452-13842532 ( 40) CCTGACAA 1 chr2:219221525-219221605 ( 38) CATGGAGA 1 chr18:20773854-20773934 ( 58) CATAGCAG 1 chr21:44847193-44847273 ( 57) CCTGGCGA 1 chr2:74648739-74648819 ( 18) CTGGGCAA 1 chr16:81554877-81554957 ( 12) CATGGTAG 1 chr19:6066794-6066874 ( 68) CTGGGCAA 1 chr1:33546612-33546692 ( 53) CAGGGCTA 1 chr8:27696610-27696690 ( 54) CATAGCAT 1 chr15:72598732-72598812 ( 57) CATAGCCA 1 chr5:176884805-176884885 ( 61) CAGGGAAA 1 chr8:57119854-57119934 ( 63) CATAGTGA 1 chr19:46296104-46296184 ( 11) CCGGGCAA 1 chr19:59084188-59084268 ( 20) CTAGGCAA 1 chr1:40157363-40157443 ( 50) TATGGAAA 1 chr17:46102469-46102549 ( 21) TAGGGCAA 1 chr12:6716690-6716770 ( 14) CCGGGCAA 1 chr5:108804597-108804677 ( 38) CATGGTCA 1 chr7:100273249-100273329 ( 45) CTAGGCAA 1 chr17:46826608-46826688 ( 51) CATGGTAT 1 chr17:9479909-9479989 ( 40) CATAACGA 1 chr7:101397802-101397882 ( 60) TCTGGCAA 1 chr1:110163572-110163652 ( 63) CATGAGAA 1 chr3:59035848-59035928 ( 39) CCAGGCAA 1 chr12:96883287-96883367 ( 52) CCAGGCAA 1 chr19:720204-720284 ( 31) CATGGGGA 1 chr7:155414274-155414354 ( 50) CATAAAAA 1 chr6:157274853-157274933 ( 54) TATGGTGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGGCAA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 7.03193 E= 1.2e-185 -1414 185 -1414 -239 185 -240 -1414 -169 -264 -1414 -209 195 -59 -1414 169 -1414 -87 -1414 174 -1414 -245 161 -396 -80 180 -399 -155 -222 197 -1414 -323 -380 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGGCAA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 180 E= 1.2e-185 0.000000 0.955556 0.000000 0.044444 0.877778 0.050000 0.000000 0.072222 0.038889 0.000000 0.061111 0.900000 0.161111 0.000000 0.838889 0.000000 0.133333 0.000000 0.866667 0.000000 0.044444 0.805556 0.016667 0.133333 0.844444 0.016667 0.088889 0.050000 0.955556 0.000000 0.027778 0.016667 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGGCAA MEME-1 regular expression -------------------------------------------------------------------------------- CATGGCAA -------------------------------------------------------------------------------- Time 4.90 secs. ******************************************************************************** ******************************************************************************** MOTIF TTGCCATG MEME-2 width = 8 sites = 56 llr = 478 E-value = 2.5e-029 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTGCCATG MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::1::a11 pos.-specific C :::a9:1: probability G ::7:::19 matrix T aa2:1:8: bits 2.1 * * 1.9 ** * * 1.7 ** * * 1.5 ** *** Relative 1.3 ** *** * Entropy 1.1 ** *** * (12.3 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTGCCATG consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGCCATG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrX:1033501-1033581 32 1.43e-05 ccaggtatcg ttgccatg gcaacacgcc chr3:14316127-14316207 23 1.43e-05 catcgggttg ttgccatg gaaaggggtg chr19:17854832-17854912 20 1.43e-05 atcagggttg ttgccatg gaaaagggtg chr1:208267816-208267896 54 1.43e-05 TCATACTCTG TTGCCATG GAGATAAGAT chr12:76486317-76486397 16 1.43e-05 cagtttacca ttgccatg gcaacacctg chr7:157100714-157100794 48 1.43e-05 cttcctgacg ttgccatg gcatttgtaa chr17:49205584-49205664 14 1.43e-05 tgttgggtca ttgccatg gaaatgggtg chr11:65951332-65951412 20 1.43e-05 ctgcaggttg ttgccatg gaaaggagta chr19:28887377-28887457 22 1.43e-05 cagtttactg ttgccatg gcaacactgg chr12:116944238-11694431 14 1.43e-05 caatttacca ttgccatg gcaacacctg chr22:39615565-39615645 16 1.43e-05 cactttacca ttgccatg gcaacatcca chr11:125387190-12538727 25 1.43e-05 GGCTGCCAGG TTGCCATG CCAATAAGGT chrX:71314903-71314983 50 1.43e-05 ATGGCCCCTG TTGCCATG GTTCCCAAGC chr5:149893451-149893531 40 1.43e-05 AAGTGCAGCG TTGCCATG GCGTCTCCAT chr7:100104305-100104385 19 1.43e-05 cggtaggtgg ttgccatg gaaaggggag chr1:20335073-20335153 21 1.43e-05 ggtcatcacg ttgccatg gaaaggagcg chr20:30085820-30085900 51 1.43e-05 TTAGAGATAG TTGCCATG GCAACCACTA chr1:201643320-201643400 48 1.43e-05 GGGACTTGGG TTGCCATG GAAACTTGTC chr19:42500248-42500328 70 1.43e-05 GACTGGGCTG TTGCCATG GAG chr8:57121488-57121568 33 2.71e-05 TGTGTAAACT TTTCCATG GTGTTGGTGT chr7:1577742-1577822 14 2.71e-05 GGCTTCTCGG TTTCCATG ACAACCGTGG chr10:17514978-17515058 64 2.71e-05 ttacttctcc tttccatg gtaacaacc chr16:58529163-58529243 28 2.71e-05 ATAGCTCCTG TTTCCATG ACAGCTGTTG chr7:16503299-16503379 36 2.71e-05 CTTGGCTACA TTTCCATG AATTTTATGG chr6:36313997-36314077 52 2.71e-05 ttaccgcccc tttccatg acaactacct chr19:3271065-3271145 4 2.71e-05 CGG TTTCCATG GCAACAACAA chr2:64632073-64632153 20 4.04e-05 caattcaccg ttgccata gcaacatgtg chr10:134124962-13412504 49 5.30e-05 GGACACTTGG TTGCTATG GTGACAGTAT chr20:1305899-1305979 39 5.30e-05 GTTACGGCGG TTGCTATG GGCTACGGCG chr17:44855449-44855529 24 5.30e-05 TAGATGGTGG TTGCTATG GTTACGGTGT chr1:39564347-39564427 55 5.30e-05 ATTTTGAGGG TTGCTATG GTGATGGGCT chr21:44847193-44847273 10 6.80e-05 ATCGGGCGG TTGCCAAG AGACTGGCGG chr1:155164670-155164750 11 6.80e-05 ACTCCCGGCA TTGCCAAG CAACAGCCAT chr3:129033833-129033913 28 6.80e-05 ACGACGGCCG TTGCCAAG GCCGAGAGCC chr16:29675603-29675683 60 9.73e-05 GGACCCCCTG TTACCATG ACAACTGGCT chr19:6066794-6066874 23 9.73e-05 GTAACAACGG TTGCCAGG GGCAACGCAG chr19:14411305-14411385 17 9.73e-05 cggtttacga ttaccatg gcaacacctg chr9:129486225-129486305 19 9.73e-05 ACCATCAGTG TTACCATG GTTACCATCT chr12:7009210-7009290 72 1.09e-04 ttactgcctt tttccata a chr9:136070174-136070254 10 1.09e-04 tcagttgcc tttccata caccaacaat chr10:3916061-3916141 18 1.09e-04 ACTGTCACTG TTTCCATA GATACACTGA chr14:60043518-60043598 25 1.37e-04 GGATTGCCGG TTGCCACG GGCAACGAGG chr19:720204-720284 47 1.37e-04 GACGGCGCGG TTGCCACG GCGACCGCCT chr12:96883287-96883367 35 1.37e-04 GGATGCCCGG TTGCCACG AGACCGTCGC chr19:46981762-46981842 52 1.50e-04 TGTGCTGTGG TTTCCAAG GCAACAACTG chr22:32360094-32360174 34 1.64e-04 TAGGCAACTG TTTCCAGG ACAGTGACAT chr1:207884842-207884922 59 1.64e-04 ttaccacccc tttccagg aaagttctaa chr3:129418184-129418264 18 1.80e-04 acttccacaa gtgccatg acagtttaca chr19:51243474-51243554 30 1.80e-04 acgcccacca gtgccatg tcagtttccc chr9:3525842-3525922 68 1.92e-04 AAGGCAACGG TTGCTATA ACTCA chr11:15988797-15988877 24 1.92e-04 ACACCCAGTG TTGCTATA GGAACCAAAG chr15:90728478-90728558 50 2.21e-04 TGGGCCCGCG TTCCCATG GCCACCGGGG chr18:3013516-3013596 66 2.35e-04 GAGAGCCCAA TTGCCAAA AAGGAAT chr3:11759646-11759726 10 2.35e-04 ATTAAAATT TTGCCAAA GTTAAACAAC chr1:42814313-42814393 48 2.61e-04 AAATAATCAG TTGTCATG GTAACATGAT chr8:22858358-22858438 12 3.14e-04 GGGATACTGG TTGCTAGG AGACAAGCCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGCCATG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrX:1033501-1033581 1.4e-05 31_[+2]_41 chr3:14316127-14316207 1.4e-05 22_[+2]_50 chr19:17854832-17854912 1.4e-05 19_[+2]_53 chr1:208267816-208267896 1.4e-05 53_[+2]_19 chr12:76486317-76486397 1.4e-05 15_[+2]_57 chr7:157100714-157100794 1.4e-05 47_[+2]_25 chr17:49205584-49205664 1.4e-05 13_[+2]_59 chr11:65951332-65951412 1.4e-05 19_[+2]_53 chr19:28887377-28887457 1.4e-05 21_[+2]_51 chr12:116944238-11694431 1.4e-05 13_[+2]_59 chr22:39615565-39615645 1.4e-05 15_[+2]_57 chr11:125387190-12538727 1.4e-05 24_[+2]_48 chrX:71314903-71314983 1.4e-05 49_[+2]_23 chr5:149893451-149893531 1.4e-05 39_[+2]_33 chr7:100104305-100104385 1.4e-05 18_[+2]_54 chr1:20335073-20335153 1.4e-05 20_[+2]_52 chr20:30085820-30085900 1.4e-05 50_[+2]_22 chr1:201643320-201643400 1.4e-05 47_[+2]_25 chr19:42500248-42500328 1.4e-05 69_[+2]_3 chr8:57121488-57121568 2.7e-05 32_[+2]_40 chr7:1577742-1577822 2.7e-05 13_[+2]_59 chr10:17514978-17515058 2.7e-05 63_[+2]_9 chr16:58529163-58529243 2.7e-05 27_[+2]_45 chr7:16503299-16503379 2.7e-05 35_[+2]_37 chr6:36313997-36314077 2.7e-05 51_[+2]_21 chr19:3271065-3271145 2.7e-05 3_[+2]_69 chr2:64632073-64632153 4e-05 19_[+2]_53 chr10:134124962-13412504 5.3e-05 48_[+2]_24 chr20:1305899-1305979 5.3e-05 38_[+2]_34 chr17:44855449-44855529 5.3e-05 23_[+2]_49 chr1:39564347-39564427 5.3e-05 54_[+2]_18 chr21:44847193-44847273 6.8e-05 9_[+2]_63 chr1:155164670-155164750 6.8e-05 10_[+2]_62 chr3:129033833-129033913 6.8e-05 27_[+2]_45 chr16:29675603-29675683 9.7e-05 59_[+2]_13 chr19:6066794-6066874 9.7e-05 22_[+2]_50 chr19:14411305-14411385 9.7e-05 16_[+2]_56 chr9:129486225-129486305 9.7e-05 18_[+2]_54 chr12:7009210-7009290 0.00011 71_[+2]_1 chr9:136070174-136070254 0.00011 9_[+2]_63 chr10:3916061-3916141 0.00011 17_[+2]_55 chr14:60043518-60043598 0.00014 24_[+2]_48 chr19:720204-720284 0.00014 46_[+2]_26 chr12:96883287-96883367 0.00014 34_[+2]_38 chr19:46981762-46981842 0.00015 51_[+2]_21 chr22:32360094-32360174 0.00016 33_[+2]_39 chr1:207884842-207884922 0.00016 58_[+2]_14 chr3:129418184-129418264 0.00018 17_[+2]_55 chr19:51243474-51243554 0.00018 29_[+2]_43 chr9:3525842-3525922 0.00019 67_[+2]_5 chr11:15988797-15988877 0.00019 23_[+2]_49 chr15:90728478-90728558 0.00022 49_[+2]_23 chr18:3013516-3013596 0.00024 65_[+2]_7 chr3:11759646-11759726 0.00024 9_[+2]_63 chr1:42814313-42814393 0.00026 47_[+2]_25 chr8:22858358-22858438 0.00031 11_[+2]_61 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGCCATG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTGCCATG width=8 seqs=56 chrX:1033501-1033581 ( 32) TTGCCATG 1 chr3:14316127-14316207 ( 23) TTGCCATG 1 chr19:17854832-17854912 ( 20) TTGCCATG 1 chr1:208267816-208267896 ( 54) TTGCCATG 1 chr12:76486317-76486397 ( 16) TTGCCATG 1 chr7:157100714-157100794 ( 48) TTGCCATG 1 chr17:49205584-49205664 ( 14) TTGCCATG 1 chr11:65951332-65951412 ( 20) TTGCCATG 1 chr19:28887377-28887457 ( 22) TTGCCATG 1 chr12:116944238-11694431 ( 14) TTGCCATG 1 chr22:39615565-39615645 ( 16) TTGCCATG 1 chr11:125387190-12538727 ( 25) TTGCCATG 1 chrX:71314903-71314983 ( 50) TTGCCATG 1 chr5:149893451-149893531 ( 40) TTGCCATG 1 chr7:100104305-100104385 ( 19) TTGCCATG 1 chr1:20335073-20335153 ( 21) TTGCCATG 1 chr20:30085820-30085900 ( 51) TTGCCATG 1 chr1:201643320-201643400 ( 48) TTGCCATG 1 chr19:42500248-42500328 ( 70) TTGCCATG 1 chr8:57121488-57121568 ( 33) TTTCCATG 1 chr7:1577742-1577822 ( 14) TTTCCATG 1 chr10:17514978-17515058 ( 64) TTTCCATG 1 chr16:58529163-58529243 ( 28) TTTCCATG 1 chr7:16503299-16503379 ( 36) TTTCCATG 1 chr6:36313997-36314077 ( 52) TTTCCATG 1 chr19:3271065-3271145 ( 4) TTTCCATG 1 chr2:64632073-64632153 ( 20) TTGCCATA 1 chr10:134124962-13412504 ( 49) TTGCTATG 1 chr20:1305899-1305979 ( 39) TTGCTATG 1 chr17:44855449-44855529 ( 24) TTGCTATG 1 chr1:39564347-39564427 ( 55) TTGCTATG 1 chr21:44847193-44847273 ( 10) TTGCCAAG 1 chr1:155164670-155164750 ( 11) TTGCCAAG 1 chr3:129033833-129033913 ( 28) TTGCCAAG 1 chr16:29675603-29675683 ( 60) TTACCATG 1 chr19:6066794-6066874 ( 23) TTGCCAGG 1 chr19:14411305-14411385 ( 17) TTACCATG 1 chr9:129486225-129486305 ( 19) TTACCATG 1 chr12:7009210-7009290 ( 72) TTTCCATA 1 chr9:136070174-136070254 ( 10) TTTCCATA 1 chr10:3916061-3916141 ( 18) TTTCCATA 1 chr14:60043518-60043598 ( 25) TTGCCACG 1 chr19:720204-720284 ( 47) TTGCCACG 1 chr12:96883287-96883367 ( 35) TTGCCACG 1 chr19:46981762-46981842 ( 52) TTTCCAAG 1 chr22:32360094-32360174 ( 34) TTTCCAGG 1 chr1:207884842-207884922 ( 59) TTTCCAGG 1 chr3:129418184-129418264 ( 18) GTGCCATG 1 chr19:51243474-51243554 ( 30) GTGCCATG 1 chr9:3525842-3525922 ( 68) TTGCTATA 1 chr11:15988797-15988877 ( 24) TTGCTATA 1 chr15:90728478-90728558 ( 50) TTCCCATG 1 chr18:3013516-3013596 ( 66) TTGCCAAA 1 chr3:11759646-11759726 ( 10) TTGCCAAA 1 chr1:42814313-42814393 ( 48) TTGTCATG 1 chr8:22858358-22858438 ( 12) TTGCTAGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGCCATG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.95106 E= 2.5e-029 -1245 -1245 -286 205 -1245 -1245 -1245 211 -218 -389 142 0 -1245 189 -1245 -370 -1245 173 -1245 -89 204 -1245 -1245 -1245 -118 -230 -186 172 -77 -1245 172 -1245 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGCCATG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 56 E= 2.5e-029 0.000000 0.000000 0.035714 0.964286 0.000000 0.000000 0.000000 1.000000 0.053571 0.017857 0.696429 0.232143 0.000000 0.982143 0.000000 0.017857 0.000000 0.875000 0.000000 0.125000 1.000000 0.000000 0.000000 0.000000 0.107143 0.053571 0.071429 0.767857 0.142857 0.000000 0.857143 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGCCATG MEME-2 regular expression -------------------------------------------------------------------------------- TT[GT]CCATG -------------------------------------------------------------------------------- Time 8.39 secs. ******************************************************************************** ******************************************************************************** MOTIF CAGTTTAC MEME-3 width = 8 sites = 23 llr = 228 E-value = 3.5e-010 ******************************************************************************** -------------------------------------------------------------------------------- Motif CAGTTTAC MEME-3 Description -------------------------------------------------------------------------------- Simplified A :a1:::a: pos.-specific C a::::::a probability G ::81:::: matrix T :::9aa:: bits 2.1 * ** 1.9 ** ** 1.7 ** **** 1.5 ** ***** Relative 1.3 ** ***** Entropy 1.1 ******** (14.3 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CAGTTTAC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGTTTAC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:7009210-7009290 30 1.34e-05 accagcacga cagtttac cattgccatg chr19:43952486-43952566 53 1.34e-05 tatgccacgt cagtttac cgttgccatg chr10:17514978-17515058 20 1.34e-05 agcgccatga cagtttac aaatgccatg chr3:129418184-129418264 27 1.34e-05 agtgccatga cagtttac aaatgccatg chr1:21716394-21716474 4 1.34e-05 tga cagtttac aaatgccatg chr12:76486317-76486397 6 1.34e-05 cttgt cagtttac cattgccatg chr1:155804460-155804540 37 1.34e-05 agcaccatga cagtttac aaatgccatg chr19:28887377-28887457 12 1.34e-05 tgagccgcgt cagtttac tgttgccatg chr1:207752863-207752943 36 1.34e-05 agcaccatga cagtttac aaatgccatg chr19:39536863-39536943 14 1.34e-05 cagagcatga cagtttac aaatgccatg chr1:26459157-26459237 3 1.34e-05 gt cagtttac cgttgtcata chr20:1404636-1404716 16 1.34e-05 agtgccgtga cagtttac aaatgccatg chr20:42072889-42072969 41 1.34e-05 agtgccctgt cagtttac tgttgccatg chr1:207884842-207884922 16 1.34e-05 agcactgtga cagtttac aaatgccatg chr6:36313997-36314077 10 2.58e-05 gcgccatgt caatttac cattgccatg chr12:116944238-11694431 4 2.58e-05 cgt caatttac cattgccatg chr18:19747862-19747942 23 2.58e-05 TGTTTAGAAG CAATTTAC AACGAAGAAT chr7:73983919-73983999 26 4.08e-05 GCGCTGTCTT CAGGTTAC CATGGTAACC chr20:1305899-1305979 26 4.08e-05 CCGGTTGCTA CAGGTTAC GGCGGTTGCT chr14:29247992-29248072 26 4.08e-05 AGGCAGATGT CAGGTTAC TTGTATCCAA chr22:39615565-39615645 6 6.61e-05 cttgt cactttac cattgccatg chr1:25254680-25254760 36 6.61e-05 GGACCAGGCC CAGTTTAT TGGCCTCTGC chr19:51243474-51243554 39 8.06e-05 agtgccatgt cagtttcc cgttgccatg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGTTTAC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:7009210-7009290 1.3e-05 29_[+3]_43 chr19:43952486-43952566 1.3e-05 52_[+3]_20 chr10:17514978-17515058 1.3e-05 19_[+3]_53 chr3:129418184-129418264 1.3e-05 26_[+3]_46 chr1:21716394-21716474 1.3e-05 3_[+3]_69 chr12:76486317-76486397 1.3e-05 5_[+3]_67 chr1:155804460-155804540 1.3e-05 36_[+3]_36 chr19:28887377-28887457 1.3e-05 11_[+3]_61 chr1:207752863-207752943 1.3e-05 35_[+3]_37 chr19:39536863-39536943 1.3e-05 13_[+3]_59 chr1:26459157-26459237 1.3e-05 2_[+3]_70 chr20:1404636-1404716 1.3e-05 15_[+3]_57 chr20:42072889-42072969 1.3e-05 40_[+3]_32 chr1:207884842-207884922 1.3e-05 15_[+3]_57 chr6:36313997-36314077 2.6e-05 9_[+3]_63 chr12:116944238-11694431 2.6e-05 3_[+3]_69 chr18:19747862-19747942 2.6e-05 22_[+3]_50 chr7:73983919-73983999 4.1e-05 25_[+3]_47 chr20:1305899-1305979 4.1e-05 25_[+3]_47 chr14:29247992-29248072 4.1e-05 25_[+3]_47 chr22:39615565-39615645 6.6e-05 5_[+3]_67 chr1:25254680-25254760 6.6e-05 35_[+3]_37 chr19:51243474-51243554 8.1e-05 38_[+3]_34 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGTTTAC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CAGTTTAC width=8 seqs=23 chr12:7009210-7009290 ( 30) CAGTTTAC 1 chr19:43952486-43952566 ( 53) CAGTTTAC 1 chr10:17514978-17515058 ( 20) CAGTTTAC 1 chr3:129418184-129418264 ( 27) CAGTTTAC 1 chr1:21716394-21716474 ( 4) CAGTTTAC 1 chr12:76486317-76486397 ( 6) CAGTTTAC 1 chr1:155804460-155804540 ( 37) CAGTTTAC 1 chr19:28887377-28887457 ( 12) CAGTTTAC 1 chr1:207752863-207752943 ( 36) CAGTTTAC 1 chr19:39536863-39536943 ( 14) CAGTTTAC 1 chr1:26459157-26459237 ( 3) CAGTTTAC 1 chr20:1404636-1404716 ( 16) CAGTTTAC 1 chr20:42072889-42072969 ( 41) CAGTTTAC 1 chr1:207884842-207884922 ( 16) CAGTTTAC 1 chr6:36313997-36314077 ( 10) CAATTTAC 1 chr12:116944238-11694431 ( 4) CAATTTAC 1 chr18:19747862-19747942 ( 23) CAATTTAC 1 chr7:73983919-73983999 ( 26) CAGGTTAC 1 chr20:1305899-1305979 ( 26) CAGGTTAC 1 chr14:29247992-29248072 ( 26) CAGGTTAC 1 chr22:39615565-39615645 ( 6) CACTTTAC 1 chr1:25254680-25254760 ( 36) CAGTTTAT 1 chr19:51243474-51243554 ( 39) CAGTTTCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGTTTAC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.0332 E= 3.5e-010 -1117 192 -1117 -1117 204 -1117 -1117 -1117 -90 -260 167 -1117 -1117 -1117 -99 190 -1117 -1117 -1117 211 -1117 -1117 -1117 211 198 -260 -1117 -1117 -1117 185 -1117 -242 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGTTTAC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 23 E= 3.5e-010 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.130435 0.043478 0.826087 0.000000 0.000000 0.000000 0.130435 0.869565 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.956522 0.043478 0.000000 0.000000 0.000000 0.956522 0.000000 0.043478 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGTTTAC MEME-3 regular expression -------------------------------------------------------------------------------- CAGTTTAC -------------------------------------------------------------------------------- Time 11.77 secs. ******************************************************************************** ******************************************************************************** MOTIF SSBGTTGC MEME-4 width = 8 sites = 67 llr = 478 E-value = 3.5e-003 ******************************************************************************** -------------------------------------------------------------------------------- Motif SSBGTTGC MEME-4 Description -------------------------------------------------------------------------------- Simplified A 1::::::: pos.-specific C 253::::9 probability G 433a::a: matrix T 224:aa:1 bits 2.1 ** 1.9 **** 1.7 **** 1.5 ***** Relative 1.3 ***** Entropy 1.1 ***** (10.3 bits) 0.8 ***** 0.6 ***** 0.4 * ***** 0.2 ******** 0.0 -------- Multilevel GCTGTTGC consensus CGC sequence TG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SSBGTTGC MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:57980529-57980609 13 1.53e-05 GGAAAGCTGA GCTGTTGC CTGTAGATAC chr1:43613510-43613590 7 1.53e-05 CCGAGC GCTGTTGC CTGGAGACCA chr5:88025335-88025415 10 1.53e-05 AAGAGACCA GCTGTTGC CATAGTAACC chr16:58529163-58529243 39 1.53e-05 TTCCATGACA GCTGTTGC CAGGACAACC chr17:58239103-58239183 23 1.53e-05 GGGTGGTATT GCTGTTGC CATGGCAACC chr21:44847193-44847273 49 6.49e-05 GCGGGATGAG GCCGTTGC CCTGGCGACC chr17:41132490-41132570 48 6.49e-05 AGGCCACCGC GCCGTTGC CATGGCAGCA chr3:14316127-14316207 51 6.49e-05 gtaacgtctg ggtgttgc catggcaatg chr17:49205584-49205664 42 6.49e-05 gtaacttctg ggtgttgc catggcaatg chr11:65951332-65951412 48 6.49e-05 gtgacatctg ggtgttgc catggcaatg chr3:13084547-13084627 9 6.49e-05 CAGCGCCT GCCGTTGC CTGGGCGACG chr17:64188279-64188359 19 6.49e-05 AGCCTGCGGT GCGGTTGC CATGGCGACG chr7:32945097-32945177 27 6.49e-05 gcaacttctg ggtgttgc catggcaatg chr1:20335073-20335153 49 6.49e-05 ataacttcca ggtgttgc catggcaatg chr7:35077221-35077301 15 6.49e-05 CTAGCCCGCC GCCGTTGC CGCCGCTCCG chr2:241771942-241772022 48 6.49e-05 TCTCAGCAGC GCCGTTGC CATAGCAACG chr20:57482988-57483068 43 1.08e-04 GAACTGTGGT TCTGTTGC CATGGTAACA chr15:90728478-90728558 14 1.08e-04 GCCCGGGGAG CCTGTTGC CATGGCAGCG chr17:38375048-38375128 20 1.08e-04 GTGGCCTGCC TCTGTTGC CATGACAACC chr19:55690776-55690856 53 1.08e-04 CGGGCAACGG GTTGTTGC CAGGACAACG chrX:71314903-71314983 31 1.08e-04 GTGCTTGGCC CCTGTTGC CATGGCCCCT chr2:11531853-11531933 43 1.08e-04 CAGCGCCTTT GTTGTTGC CATGGCAACC chr8:125622624-125622704 37 1.08e-04 CGGGAACAGA TCTGTTGC CATGACAACA chr2:121010371-121010451 16 1.56e-04 CTCGAGAGGA GGGGTTGC CTAGGCGACG chr19:720204-720284 23 1.56e-04 gccgggccTC GGCGTTGC CATGGGGACG chr11:62537436-62537516 42 1.56e-04 CTCCTTAGGT GGGGTTGC CATGGCAACC chr1:155164670-155164750 34 2.81e-04 GCCATTCAGT TCGGTTGC TGGGACACGC chr20:1305899-1305979 16 2.81e-04 GCGACATCTT CCGGTTGC TACAGGTTAC chr1:33546612-33546692 45 2.81e-04 ATGGCGGCAC CCGGTTGC CAGGGCTACG chr1:208267816-208267896 6 2.81e-04 GCATC TGTGTTGC CATAGCAATA chr2:232469502-232469582 20 2.81e-04 AGAGGCTGAG CCGGTTGC TGCGCGACGG chr5:176884805-176884885 53 2.81e-04 GATTCCATCA GTGGTTGC CAGGGAAACA chr11:76758786-76758866 34 2.81e-04 gtaacttccg gtcgttgc catggcattt chr12:54653403-54653483 22 2.81e-04 GCTGTCCCAG TCCGTTGC CATAGCAACT chr19:42500248-42500328 5 3.07e-04 GTCC TTTGTTGC CATGGTAACA chr1:40157363-40157443 42 3.53e-04 AAACAACCTC ACCGTTGC TATGGAAACG chr10:103348021-10334810 27 3.53e-04 ACCCTCTGGA ACGGTTGC CATGGCAGCG chr16:81554877-81554957 4 3.53e-04 TGC ACGGTTGC CATGGTAGCA chr5:43193865-43193945 14 3.53e-04 GGTTTCTGTT AGTGTTGC AACAGCACTT chr7:100273249-100273329 37 3.53e-04 GGTCCGGGTG ACGGTTGC CTAGGCAACC chr9:35114226-35114306 56 3.53e-04 TCTGGGAAGC AGTGTTGC CATAGCAATC chr11:64902595-64902675 50 4.30e-04 GGCGGACAGC TGCGTTGC CTAGGCCCTG chr11:27384823-27384903 19 4.30e-04 GCACAGACCC CGCGTTGC CATGGCGACG chr8:27696610-27696690 46 4.30e-04 ataagttccc cgggttgc catagcattt chr19:18263385-18263465 48 4.30e-04 CCGGACGCTC TGGGTTGC CATGGAAACT chr22:38453088-38453168 14 4.88e-04 CAGGGATGCT TTCGTTGC CATGGCAAcc chr19:14492940-14493020 42 4.88e-04 ATCAGGGTAG CTCGTTGC CTAAGCAACG chr2:219221525-219221605 30 4.88e-04 CTGTCCAGCT CTGGTTGC CATGGAGACA chr6:16410065-16410145 72 4.88e-04 GCTGATGATG CTGGTTGC G chr15:72598732-72598812 23 4.88e-04 TACCAATTTG CTCGTTGC CGAGACAACA chr16:30959615-30959695 21 4.88e-04 ACTGCCACTC CTGGTTGC CATGGAAATA chr6:25988235-25988315 48 4.88e-04 atgtcagttt ttcgttgc catggcaaca chr6:157274853-157274933 46 5.34e-04 GCATACTGTT AGCGTTGC TATGGTGACA chr3:59035848-59035928 31 5.34e-04 GCGGTGACGT AGCGTTGC CCAGGCAACC chr19:3271065-3271145 46 5.34e-04 GTGGTGAATC AGCGTTGC CATGGCAACC chr10:76349135-76349215 52 5.78e-04 GAGCCTCGCA GCAGTTGC CATGGAAACT chr7:16503299-16503379 10 5.78e-04 CAGGAACGT ATGGTTGC CATAACAACT chr7:617674-617754 12 6.22e-04 ggagcgcccg ggtgttgt catggcaacg chr7:100104305-100104385 47 6.22e-04 ataacttctg ggtgttgt catggcaacg chr1:201622493-201622573 25 6.22e-04 ACCCACACAA GCGGTTGT CATGACAACA chr9:3525842-3525922 1 6.75e-04 . GTTGTTGT TGATGGGTAA chr1:12719160-12719240 51 6.75e-04 TCTAGCTGGA CCTGTTGT CATGGGAaca chr10:103157018-10315709 50 6.75e-04 TAAGCTGCAT CCTGTTGT CATGGCAACC chr8:22858358-22858438 45 6.75e-04 CCAGGGAGAT TCTGTTGT TTCCTTGACA chr5:154237392-154237472 15 7.19e-04 CCCTGGCGGG CCAGTTGC TATGGCAATG chr9:136070174-136070254 1 7.19e-04 . tcagttgc ctttccatac chr3:129033833-129033913 64 1.20e-03 CGTCGCCGGG GCTGTTTC AAAAACCTA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SSBGTTGC MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:57980529-57980609 1.5e-05 12_[+4]_60 chr1:43613510-43613590 1.5e-05 6_[+4]_66 chr5:88025335-88025415 1.5e-05 9_[+4]_63 chr16:58529163-58529243 1.5e-05 38_[+4]_34 chr17:58239103-58239183 1.5e-05 22_[+4]_50 chr21:44847193-44847273 6.5e-05 48_[+4]_24 chr17:41132490-41132570 6.5e-05 47_[+4]_25 chr3:14316127-14316207 6.5e-05 50_[+4]_22 chr17:49205584-49205664 6.5e-05 41_[+4]_31 chr11:65951332-65951412 6.5e-05 47_[+4]_25 chr3:13084547-13084627 6.5e-05 8_[+4]_64 chr17:64188279-64188359 6.5e-05 18_[+4]_54 chr7:32945097-32945177 6.5e-05 26_[+4]_46 chr1:20335073-20335153 6.5e-05 48_[+4]_24 chr7:35077221-35077301 6.5e-05 14_[+4]_58 chr2:241771942-241772022 6.5e-05 47_[+4]_25 chr20:57482988-57483068 0.00011 42_[+4]_30 chr15:90728478-90728558 0.00011 13_[+4]_59 chr17:38375048-38375128 0.00011 19_[+4]_53 chr19:55690776-55690856 0.00011 52_[+4]_20 chrX:71314903-71314983 0.00011 30_[+4]_42 chr2:11531853-11531933 0.00011 42_[+4]_30 chr8:125622624-125622704 0.00011 36_[+4]_36 chr2:121010371-121010451 0.00016 15_[+4]_57 chr19:720204-720284 0.00016 22_[+4]_50 chr11:62537436-62537516 0.00016 41_[+4]_31 chr1:155164670-155164750 0.00028 33_[+4]_39 chr20:1305899-1305979 0.00028 15_[+4]_57 chr1:33546612-33546692 0.00028 44_[+4]_28 chr1:208267816-208267896 0.00028 5_[+4]_67 chr2:232469502-232469582 0.00028 19_[+4]_53 chr5:176884805-176884885 0.00028 52_[+4]_20 chr11:76758786-76758866 0.00028 33_[+4]_39 chr12:54653403-54653483 0.00028 21_[+4]_51 chr19:42500248-42500328 0.00031 4_[+4]_68 chr1:40157363-40157443 0.00035 41_[+4]_31 chr10:103348021-10334810 0.00035 26_[+4]_46 chr16:81554877-81554957 0.00035 3_[+4]_69 chr5:43193865-43193945 0.00035 13_[+4]_59 chr7:100273249-100273329 0.00035 36_[+4]_36 chr9:35114226-35114306 0.00035 55_[+4]_17 chr11:64902595-64902675 0.00043 49_[+4]_23 chr11:27384823-27384903 0.00043 18_[+4]_54 chr8:27696610-27696690 0.00043 45_[+4]_27 chr19:18263385-18263465 0.00043 47_[+4]_25 chr22:38453088-38453168 0.00049 13_[+4]_59 chr19:14492940-14493020 0.00049 41_[+4]_31 chr2:219221525-219221605 0.00049 29_[+4]_43 chr6:16410065-16410145 0.00049 71_[+4]_1 chr15:72598732-72598812 0.00049 22_[+4]_50 chr16:30959615-30959695 0.00049 20_[+4]_52 chr6:25988235-25988315 0.00049 47_[+4]_25 chr6:157274853-157274933 0.00053 45_[+4]_27 chr3:59035848-59035928 0.00053 30_[+4]_42 chr19:3271065-3271145 0.00053 45_[+4]_27 chr10:76349135-76349215 0.00058 51_[+4]_21 chr7:16503299-16503379 0.00058 9_[+4]_63 chr7:617674-617754 0.00062 11_[+4]_61 chr7:100104305-100104385 0.00062 46_[+4]_26 chr1:201622493-201622573 0.00062 24_[+4]_48 chr9:3525842-3525922 0.00067 [+4]_72 chr1:12719160-12719240 0.00067 50_[+4]_22 chr10:103157018-10315709 0.00067 49_[+4]_23 chr8:22858358-22858438 0.00067 44_[+4]_28 chr5:154237392-154237472 0.00072 14_[+4]_58 chr9:136070174-136070254 0.00072 [+4]_72 chr3:129033833-129033913 0.0012 63_[+4]_9 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SSBGTTGC MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF SSBGTTGC width=8 seqs=67 chr16:57980529-57980609 ( 13) GCTGTTGC 1 chr1:43613510-43613590 ( 7) GCTGTTGC 1 chr5:88025335-88025415 ( 10) GCTGTTGC 1 chr16:58529163-58529243 ( 39) GCTGTTGC 1 chr17:58239103-58239183 ( 23) GCTGTTGC 1 chr21:44847193-44847273 ( 49) GCCGTTGC 1 chr17:41132490-41132570 ( 48) GCCGTTGC 1 chr3:14316127-14316207 ( 51) GGTGTTGC 1 chr17:49205584-49205664 ( 42) GGTGTTGC 1 chr11:65951332-65951412 ( 48) GGTGTTGC 1 chr3:13084547-13084627 ( 9) GCCGTTGC 1 chr17:64188279-64188359 ( 19) GCGGTTGC 1 chr7:32945097-32945177 ( 27) GGTGTTGC 1 chr1:20335073-20335153 ( 49) GGTGTTGC 1 chr7:35077221-35077301 ( 15) GCCGTTGC 1 chr2:241771942-241772022 ( 48) GCCGTTGC 1 chr20:57482988-57483068 ( 43) TCTGTTGC 1 chr15:90728478-90728558 ( 14) CCTGTTGC 1 chr17:38375048-38375128 ( 20) TCTGTTGC 1 chr19:55690776-55690856 ( 53) GTTGTTGC 1 chrX:71314903-71314983 ( 31) CCTGTTGC 1 chr2:11531853-11531933 ( 43) GTTGTTGC 1 chr8:125622624-125622704 ( 37) TCTGTTGC 1 chr2:121010371-121010451 ( 16) GGGGTTGC 1 chr19:720204-720284 ( 23) GGCGTTGC 1 chr11:62537436-62537516 ( 42) GGGGTTGC 1 chr1:155164670-155164750 ( 34) TCGGTTGC 1 chr20:1305899-1305979 ( 16) CCGGTTGC 1 chr1:33546612-33546692 ( 45) CCGGTTGC 1 chr1:208267816-208267896 ( 6) TGTGTTGC 1 chr2:232469502-232469582 ( 20) CCGGTTGC 1 chr5:176884805-176884885 ( 53) GTGGTTGC 1 chr11:76758786-76758866 ( 34) GTCGTTGC 1 chr12:54653403-54653483 ( 22) TCCGTTGC 1 chr19:42500248-42500328 ( 5) TTTGTTGC 1 chr1:40157363-40157443 ( 42) ACCGTTGC 1 chr10:103348021-10334810 ( 27) ACGGTTGC 1 chr16:81554877-81554957 ( 4) ACGGTTGC 1 chr5:43193865-43193945 ( 14) AGTGTTGC 1 chr7:100273249-100273329 ( 37) ACGGTTGC 1 chr9:35114226-35114306 ( 56) AGTGTTGC 1 chr11:64902595-64902675 ( 50) TGCGTTGC 1 chr11:27384823-27384903 ( 19) CGCGTTGC 1 chr8:27696610-27696690 ( 46) CGGGTTGC 1 chr19:18263385-18263465 ( 48) TGGGTTGC 1 chr22:38453088-38453168 ( 14) TTCGTTGC 1 chr19:14492940-14493020 ( 42) CTCGTTGC 1 chr2:219221525-219221605 ( 30) CTGGTTGC 1 chr6:16410065-16410145 ( 72) CTGGTTGC 1 chr15:72598732-72598812 ( 23) CTCGTTGC 1 chr16:30959615-30959695 ( 21) CTGGTTGC 1 chr6:25988235-25988315 ( 48) TTCGTTGC 1 chr6:157274853-157274933 ( 46) AGCGTTGC 1 chr3:59035848-59035928 ( 31) AGCGTTGC 1 chr19:3271065-3271145 ( 46) AGCGTTGC 1 chr10:76349135-76349215 ( 52) GCAGTTGC 1 chr7:16503299-16503379 ( 10) ATGGTTGC 1 chr7:617674-617754 ( 12) GGTGTTGT 1 chr7:100104305-100104385 ( 47) GGTGTTGT 1 chr1:201622493-201622573 ( 25) GCGGTTGT 1 chr9:3525842-3525922 ( 1) GTTGTTGT 1 chr1:12719160-12719240 ( 51) CCTGTTGT 1 chr10:103157018-10315709 ( 50) CCTGTTGT 1 chr8:22858358-22858438 ( 45) TCTGTTGT 1 chr5:154237392-154237472 ( 15) CCAGTTGC 1 chr9:136070174-136070254 ( 1) TCAGTTGC 1 chr3:129033833-129033913 ( 64) GCTGTTTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SSBGTTGC MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 8.86712 E= 3.5e-003 -70 -24 74 -26 -1271 90 20 -15 -244 2 5 85 -1271 -1271 194 -1271 -1271 -1271 -1271 211 -1271 -1271 -1271 211 -1271 -1271 192 -396 -1271 176 -1271 -115 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SSBGTTGC MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 67 E= 3.5e-003 0.149254 0.223881 0.432836 0.194030 0.000000 0.492537 0.298507 0.208955 0.044776 0.268657 0.268657 0.417910 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.985075 0.014925 0.000000 0.895522 0.000000 0.104478 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif SSBGTTGC MEME-4 regular expression -------------------------------------------------------------------------------- [GC][CGT][TCG]GTTGC -------------------------------------------------------------------------------- Time 15.04 secs. ******************************************************************************** ******************************************************************************** MOTIF GAAGTTAC MEME-5 width = 8 sites = 16 llr = 159 E-value = 1.4e-001 ******************************************************************************** -------------------------------------------------------------------------------- Motif GAAGTTAC MEME-5 Description -------------------------------------------------------------------------------- Simplified A :aa2::9: pos.-specific C ::::::1a probability G a::8:1:: matrix T ::::a9:: bits 2.1 ** * 1.9 *** * * 1.7 *** * * 1.5 *** **** Relative 1.3 ******** Entropy 1.1 ******** (14.3 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GAAGTTAC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAAGTTAC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:7009210-7009290 58 1.38e-05 gcgacaccca gaagttac tgcctttttc chr3:129418184-129418264 55 1.38e-05 gcaacgtcca gaagttac cctatatggt chr18:12904071-12904151 27 1.38e-05 gcaacgtcag gaagttac cctacatggt chr12:76486317-76486397 67 1.38e-05 caatgacctg gaagttac tacgct chr1:207752863-207752943 65 1.38e-05 caacgaccta gaagttac cgcccctt chr6:36313997-36314077 38 1.38e-05 gcaacaccca gaagttac cgcccctttc chr19:39536863-39536943 43 1.38e-05 caacgacctg gaagttac cgcccctttt chr1:26459157-26459237 72 1.38e-05 tgacgactca gaagttac c chr1:207884842-207884922 45 1.38e-05 caacgatctg gaagttac cacccctttc chr10:17514978-17515058 50 2.67e-05 aacaacccag gaaattac ttctcctttc chr6:157274853-157274933 8 2.67e-05 GAAGTCT GAAATTAC ATCTTTGTCT chr1:21716394-21716474 32 2.67e-05 gcaacgtcta gaaattac tctctatggt chr14:71786920-71787000 36 4.16e-05 ATAGCAACCA GAAGTTCC GCGGTCCCCT chr6:16410065-16410145 7 4.16e-05 TCTAGA GAAGTTCC ACAAAACTGT chr10:103348021-10334810 11 5.71e-05 GAGTCAGCCG GAAGTGAC CCTCTGGAAC chr22:32360094-32360174 3 5.71e-05 TG GAAGTGAC ATCACACATT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAAGTTAC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:7009210-7009290 1.4e-05 57_[+5]_15 chr3:129418184-129418264 1.4e-05 54_[+5]_18 chr18:12904071-12904151 1.4e-05 26_[+5]_46 chr12:76486317-76486397 1.4e-05 66_[+5]_6 chr1:207752863-207752943 1.4e-05 64_[+5]_8 chr6:36313997-36314077 1.4e-05 37_[+5]_35 chr19:39536863-39536943 1.4e-05 42_[+5]_30 chr1:26459157-26459237 1.4e-05 71_[+5]_1 chr1:207884842-207884922 1.4e-05 44_[+5]_28 chr10:17514978-17515058 2.7e-05 49_[+5]_23 chr6:157274853-157274933 2.7e-05 7_[+5]_65 chr1:21716394-21716474 2.7e-05 31_[+5]_41 chr14:71786920-71787000 4.2e-05 35_[+5]_37 chr6:16410065-16410145 4.2e-05 6_[+5]_66 chr10:103348021-10334810 5.7e-05 10_[+5]_62 chr22:32360094-32360174 5.7e-05 2_[+5]_70 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAAGTTAC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GAAGTTAC width=8 seqs=16 chr12:7009210-7009290 ( 58) GAAGTTAC 1 chr3:129418184-129418264 ( 55) GAAGTTAC 1 chr18:12904071-12904151 ( 27) GAAGTTAC 1 chr12:76486317-76486397 ( 67) GAAGTTAC 1 chr1:207752863-207752943 ( 65) GAAGTTAC 1 chr6:36313997-36314077 ( 38) GAAGTTAC 1 chr19:39536863-39536943 ( 43) GAAGTTAC 1 chr1:26459157-26459237 ( 72) GAAGTTAC 1 chr1:207884842-207884922 ( 45) GAAGTTAC 1 chr10:17514978-17515058 ( 50) GAAATTAC 1 chr6:157274853-157274933 ( 8) GAAATTAC 1 chr1:21716394-21716474 ( 32) GAAATTAC 1 chr14:71786920-71787000 ( 36) GAAGTTCC 1 chr6:16410065-16410145 ( 7) GAAGTTCC 1 chr10:103348021-10334810 ( 11) GAAGTGAC 1 chr22:32360094-32360174 ( 3) GAAGTGAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAAGTTAC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.8918 E= 1.4e-001 -1064 -1064 194 -1064 204 -1064 -1064 -1064 204 -1064 -1064 -1064 -37 -1064 164 -1064 -1064 -1064 -1064 210 -1064 -1064 -106 191 185 -108 -1064 -1064 -1064 192 -1064 -1064 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAAGTTAC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 16 E= 1.4e-001 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.187500 0.000000 0.812500 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.125000 0.875000 0.875000 0.125000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAAGTTAC MEME-5 regular expression -------------------------------------------------------------------------------- GAAGTTAC -------------------------------------------------------------------------------- Time 18.24 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:179615939-179616019 6.56e-02 56_[+1(1.57e-05)]_16 chr19:51243474-51243554 1.98e-06 38_[+3(8.06e-05)]_2_[+2(1.43e-05)]_\ 24 chr1:201622493-201622573 1.01e-03 32_[+1(5.88e-05)]_40 chr19:42500248-42500328 1.82e-05 8_[+2(1.43e-05)]_53_[+2(1.43e-05)]_\ 3 chr19:3271065-3271145 2.57e-05 7_[+1(1.57e-05)]_34_[+2(1.43e-05)]_\ 23 chr8:125622624-125622704 2.66e-05 40_[+2(1.43e-05)]_32 chr9:129486225-129486305 3.03e-02 18_[+2(9.73e-05)]_40_[+2(9.73e-05)]_\ 6 chr7:100087583-100087663 8.71e-04 44_[+1(1.57e-05)]_28 chr11:62537436-62537516 4.17e-06 45_[+2(1.43e-05)]_27 chr19:1860182-1860262 4.37e-02 45_[+1(3.03e-05)]_27 chr19:47972051-47972131 6.99e-04 47_[+2(1.43e-05)]_25 chr19:46981762-46981842 1.13e-03 24_[+2(2.71e-05)]_48 chr2:198799163-198799243 8.88e-02 32_[+1(3.03e-05)]_40 chr20:5695346-5695426 5.95e-04 37_[+2(9.73e-05)]_35 chr17:42905348-42905428 5.17e-01 80 chr10:43818326-43818406 4.24e-02 10_[+1(1.57e-05)]_62 chr2:241771942-241772022 6.89e-05 47_[+4(6.49e-05)]_[+1(3.03e-05)]_17 chr1:207884842-207884922 2.12e-07 15_[+3(1.34e-05)]_6_[+1(1.57e-05)]_\ 7_[+5(1.38e-05)]_28 chr1:201643320-201643400 2.26e-05 15_[+1(4.41e-05)]_24_[+2(1.43e-05)]_\ 25 chr17:7117370-7117450 1.26e-02 80 chr1:21525610-21525690 6.07e-02 9_[+1(3.03e-05)]_13_[+1(3.03e-05)]_\ 13_[+1(3.03e-05)]_13_[+1(3.03e-05)] chr1:159869921-159870001 5.10e-02 44_[+1(9.05e-05)]_28 chr17:58239103-58239183 8.12e-06 26_[+2(1.43e-05)]_46 chr7:137846440-137846520 2.50e-03 34_[+1(1.57e-05)]_38 chr22:32360094-32360174 1.54e-05 2_[+5(5.71e-05)]_52_[+1(4.41e-05)]_\ 10 chr20:30085820-30085900 6.08e-05 9_[+1(1.57e-05)]_33_[+2(1.43e-05)]_\ 22 chr3:41236359-41236439 7.14e-01 80 chr7:35077221-35077301 5.75e-02 14_[+4(6.49e-05)]_58 chr20:42072889-42072969 1.47e-07 40_[+3(1.34e-05)]_2_[+2(1.43e-05)]_\ 22 chr3:156227740-156227820 1.04e-02 60_[+1(1.57e-05)]_12 chr7:130833662-130833742 6.69e-01 80 chr1:42814313-42814393 6.57e-04 11_[+1(1.57e-05)]_32_[+1(4.41e-05)]_\ 21 chr1:20335073-20335153 4.41e-06 20_[+2(1.43e-05)]_24_[+2(1.43e-05)]_\ 20 chr17:47753699-47753779 2.20e-02 40_[+1(1.57e-05)]_32 chr20:1404636-1404716 5.12e-07 15_[+3(1.34e-05)]_6_[+1(1.57e-05)]_\ 7_[+3(9.46e-05)]_10_[+1(1.57e-05)]_10 chr8:26482876-26482956 3.83e-04 49_[+1(4.41e-05)]_23 chr3:41238212-41238292 8.27e-01 80 chr7:100104305-100104385 5.31e-05 18_[+2(1.43e-05)]_28_[+1(1.57e-05)]_\ 18 chr1:26459157-26459237 5.56e-09 2_[+3(1.34e-05)]_6_[+1(3.03e-05)]_6_\ [+5(1.38e-05)]_10_[+1(1.57e-05)]_15_[+5(1.38e-05)]_1 chr8:30294209-30294289 3.24e-01 80 chr19:17012772-17012852 2.51e-02 14_[+1(1.57e-05)]_44_[+1(1.57e-05)]_\ 6 chr18:19747862-19747942 3.52e-02 22_[+3(2.58e-05)]_50 chr16:86928668-86928748 7.98e-01 80 chr19:14411305-14411385 4.34e-05 20_[+1(1.57e-05)]_24_[+1(1.57e-05)]_\ 20 chr20:57663023-57663103 1.58e-01 80 chr19:15334361-15334441 2.08e-01 80 chr19:11484375-11484455 8.31e-04 54_[+2(9.73e-05)]_18 chr5:149893451-149893531 5.93e-04 39_[+2(1.43e-05)]_33 chr9:129482090-129482170 4.54e-04 54_[+1(1.57e-05)]_18 chr1:25254680-25254760 4.80e-02 35_[+3(6.61e-05)]_37 chr3:167098101-167098181 4.15e-02 34_[+1(3.03e-05)]_38 chr7:155414274-155414354 2.80e-01 80 chr19:39536863-39536943 1.90e-06 13_[+3(1.34e-05)]_6_[+1(1.57e-05)]_\ 7_[+5(1.38e-05)]_30 chr12:54653403-54653483 3.17e-04 29_[+1(3.03e-05)]_43 chr8:22858358-22858438 4.70e-03 80 chr19:6066794-6066874 3.16e-04 22_[+2(9.73e-05)]_50 chr2:11531853-11531933 8.09e-06 46_[+2(1.43e-05)]_26 chr8:72754915-72754995 4.56e-01 80 chr1:110163572-110163652 1.11e-01 80 chr10:3916061-3916141 3.79e-04 46_[+1(3.03e-05)]_26 chr16:29675603-29675683 1.02e-03 9_[+1(1.57e-05)]_46_[+1(5.88e-05)]_\ 9 chr7:99699532-99699612 2.44e-03 55_[+1(4.41e-05)]_17 chrX:71314903-71314983 4.10e-03 34_[+2(1.43e-05)]_7_[+2(1.43e-05)]_\ 23 chr11:76758786-76758866 5.41e-04 37_[+2(1.43e-05)]_35 chr20:5639682-5639762 1.05e-03 40_[+1(1.57e-05)]_32 chr17:46826608-46826688 5.95e-02 80 chr19:55690776-55690856 2.11e-03 56_[+2(9.73e-05)]_16 chr8:57119854-57119934 4.08e-01 80 chr7:32945097-32945177 8.52e-06 30_[+2(1.43e-05)]_42 chr12:9066910-9066990 2.40e-02 61_[+1(1.57e-05)]_11 chr2:101476528-101476608 3.82e-01 80 chr6:53357777-53357857 7.09e-02 80 chr3:142608506-142608586 6.10e-01 80 chr7:36401005-36401085 9.22e-02 80 chr17:64188279-64188359 6.32e-06 22_[+2(1.43e-05)]_50 chr11:125387190-12538727 7.19e-04 24_[+2(1.43e-05)]_48 chr14:29247992-29248072 2.33e-02 25_[+3(4.08e-05)]_47 chr7:27251511-27251591 2.27e-01 80 chr18:20773854-20773934 3.74e-01 80 chr10:103157018-10315709 1.47e-03 57_[+1(1.57e-05)]_15 chr17:38375048-38375128 7.37e-05 23_[+2(1.43e-05)]_49 chr18:44577006-44577086 5.55e-01 80 chr1:212748862-212748942 8.24e-01 80 chr8:95656926-95657006 7.62e-01 80 chr6:25988235-25988315 1.34e-05 51_[+2(1.43e-05)]_21 chr9:35114226-35114306 4.33e-04 63_[+1(3.03e-05)]_9 chr7:100273249-100273329 5.17e-02 80 chr5:43193865-43193945 3.06e-03 80 chr22:39615565-39615645 8.67e-06 5_[+3(6.61e-05)]_2_[+2(1.43e-05)]_\ 28_[+1(1.57e-05)]_21 chr16:30959615-30959695 1.19e-04 24_[+2(1.43e-05)]_48 chr5:108804597-108804677 3.98e-02 80 chr20:11873038-11873118 5.04e-03 33_[+1(3.03e-05)]_39 chr6:11055474-11055554 2.61e-01 80 chr1:180207343-180207423 5.58e-01 80 chr1:212720568-212720648 7.94e-01 80 chr16:81554877-81554957 1.33e-03 7_[+2(1.43e-05)]_65 chr19:47250073-47250153 2.43e-03 53_[+1(4.41e-05)]_19 chr1:151682829-151682909 5.23e-02 15_[+1(1.57e-05)]_57 chr8:57114896-57114976 6.09e-01 80 chr5:176884805-176884885 2.05e-03 56_[+2(9.73e-05)]_16 chr11:118528049-11852812 1.69e-03 47_[+2(1.43e-05)]_25 chrX:133938031-133938111 1.95e-03 40_[+1(5.88e-05)]_32 chr3:13084547-13084627 5.53e-02 8_[+4(6.49e-05)]_64 chr16:759701-759781 2.16e-02 16_[+1(3.03e-05)]_56 chr2:74648739-74648819 5.17e-02 80 chr3:138048641-138048721 3.81e-02 46_[+1(1.57e-05)]_26 chr2:23610861-23610941 1.32e-01 80 chr7:45129090-45129170 3.40e-02 41_[+1(1.57e-05)]_31 chr5:179364025-179364105 5.41e-01 80 chr1:100817825-100817905 2.17e-01 80 chrX:119130175-119130255 2.48e-01 80 chr12:116944238-11694431 1.48e-06 3_[+3(2.58e-05)]_2_[+2(1.43e-05)]_\ 28_[+1(1.57e-05)]_23 chr11:15988797-15988877 4.71e-03 80 chr6:36313997-36314077 2.64e-08 9_[+3(2.58e-05)]_2_[+2(1.43e-05)]_\ 10_[+5(1.38e-05)]_6_[+2(2.71e-05)]_21 chr4:47688435-47688515 1.85e-01 80 chr3:11759646-11759726 8.24e-02 80 chr5:79330452-79330532 2.76e-01 80 chr1:207752863-207752943 1.71e-06 35_[+3(1.34e-05)]_6_[+1(1.57e-05)]_\ 7_[+5(1.38e-05)]_8 chr11:34673287-34673367 2.34e-02 36_[+1(5.88e-05)]_36 chr12:96883287-96883367 8.72e-03 80 chr20:34652621-34652701 1.06e-02 23_[+1(1.57e-05)]_49 chr19:28887377-28887457 1.25e-08 11_[+3(1.34e-05)]_2_[+2(1.43e-05)]_\ 28_[+1(1.57e-05)]_15 chr7:28101881-28101961 6.21e-01 80 chr11:65951332-65951412 1.20e-06 19_[+2(1.43e-05)]_24_[+2(1.43e-05)]_\ 21 chr1:12719160-12719240 9.97e-04 80 chr3:59035848-59035928 6.17e-02 80 chr19:720204-720284 8.50e-04 26_[+2(1.43e-05)]_8_[+4(6.49e-05)]_\ 30 chr17:46226864-46226944 1.12e-03 52_[+2(2.71e-05)]_20 chr12:6716690-6716770 4.30e-01 80 chr14:60043518-60043598 1.69e-02 80 chr1:202318488-202318568 1.02e-02 80 chr11:1918258-1918338 7.41e-01 80 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chr3:39222389-39222469 5.74e-01 80 chr22:50710263-50710343 8.87e-03 21_[+1(7.56e-05)]_51 chr2:158124230-158124310 2.37e-04 31_[+1(1.57e-05)]_41 chr10:103348021-10334810 1.21e-05 10_[+5(5.71e-05)]_12_[+2(1.43e-05)]_\ 42 chr7:1577742-1577822 1.31e-04 13_[+2(2.71e-05)]_34_[+1(1.57e-05)]_\ 17 chr1:40157363-40157443 7.67e-03 45_[+2(5.30e-05)]_27 chr20:57482988-57483068 2.72e-05 46_[+2(1.43e-05)]_26 chr9:96846607-96846687 1.18e-02 80 chr3:150064026-150064106 8.56e-01 80 chr17:41132490-41132570 1.34e-04 51_[+2(1.43e-05)]_21 chr9:3525842-3525922 5.06e-03 80 chr2:66796509-66796589 7.73e-03 42_[+1(3.03e-05)]_30 chr19:59084188-59084268 5.42e-01 80 chr4:99583403-99583483 9.09e-01 80 chr19:46296104-46296184 4.54e-01 80 chr15:96873820-96873900 4.37e-03 35_[+1(1.57e-05)]_37 chr8:57121488-57121568 1.18e-03 32_[+2(2.71e-05)]_40 chr10:134124962-13412504 1.26e-02 48_[+2(5.30e-05)]_24 chrX:1033501-1033581 7.02e-06 31_[+2(1.43e-05)]_29_[+1(1.57e-05)]_\ 4 chr1:76457372-76457452 4.31e-01 80 chr11:27384823-27384903 4.66e-04 22_[+2(1.43e-05)]_50 chr21:44847193-44847273 1.08e-03 5_[+4(6.49e-05)]_35_[+4(6.49e-05)]_\ 24 chr11:64902595-64902675 8.53e-02 80 chr7:101398291-101398371 1.21e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n09.farnam.hpc.yale.internal ********************************************************************************