******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/BCLAF1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr11:61266693-61266773 1.0000 80 chr1:207779253-207779333 1.0000 80 chr2:108972836-108972916 1.0000 80 chr18:9014192-9014272 1.0000 80 chr3:129118847-129118927 1.0000 80 chr6:26033176-26033256 1.0000 80 chr6:27092342-27092422 1.0000 80 chr11:65192798-65192878 1.0000 80 chr6:27776711-27776791 1.0000 80 chr4:38324943-38325023 1.0000 80 chr1:90461681-90461761 1.0000 80 chr11:10476501-10476581 1.0000 80 chr2:171786925-171787005 1.0000 80 chr17:10694341-10694421 1.0000 80 chr5:132002197-132002277 1.0000 80 chr11:120107418-12010749 1.0000 80 chr19:5352587-5352667 1.0000 80 chr2:145116776-145116856 1.0000 80 chr1:40363001-40363081 1.0000 80 chr8:143751396-143751476 1.0000 80 chr17:56743939-56744019 1.0000 80 chr2:108361773-108361853 1.0000 80 chr1:28835000-28835080 1.0000 80 chr6:27115989-27116069 1.0000 80 chr10:23344693-23344773 1.0000 80 chr14:23120401-23120481 1.0000 80 chr6:3939328-3939408 1.0000 80 chr15:75052858-75052938 1.0000 80 chr3:13044214-13044294 1.0000 80 chr6:28188568-28188648 1.0000 80 chr11:65273319-65273399 1.0000 80 chr11:65274101-65274181 1.0000 80 chr6:27834378-27834458 1.0000 80 chr6:26031120-26031200 1.0000 80 chr11:1372908-1372988 1.0000 80 chr5:137803884-137803964 1.0000 80 chr16:2771124-2771204 1.0000 80 chr6:26126864-26126944 1.0000 80 chr12:123459193-12345927 1.0000 80 chr6:37465174-37465254 1.0000 80 chr20:52369772-52369852 1.0000 80 chr5:61561674-61561754 1.0000 80 chr6:26194647-26194727 1.0000 80 chr16:57716918-57716998 1.0000 80 chr7:2913806-2913886 1.0000 80 chr8:125827797-125827877 1.0000 80 chr19:13211029-13211109 1.0000 80 chr2:30884273-30884353 1.0000 80 chr5:77074985-77075065 1.0000 80 chr16:30538161-30538241 1.0000 80 chr11:65190911-65190991 1.0000 80 chr11:65270501-65270581 1.0000 80 chr1:155112995-155113075 1.0000 80 chr13:114103626-11410370 1.0000 80 chr6:15211639-15211719 1.0000 80 chr1:210547450-210547530 1.0000 80 chr19:5309096-5309176 1.0000 80 chr12:49667262-49667342 1.0000 80 chr1:36866739-36866819 1.0000 80 chr19:56092291-56092371 1.0000 80 chr4:68441103-68441183 1.0000 80 chr6:15211429-15211509 1.0000 80 chr6:119215197-119215277 1.0000 80 chr2:152685351-152685431 1.0000 80 chr17:26421222-26421302 1.0000 80 chr17:57916863-57916943 1.0000 80 chr2:99952938-99953018 1.0000 80 chr17:41393322-41393402 1.0000 80 chr6:27101649-27101729 1.0000 80 chr16:89160192-89160272 1.0000 80 chr12:45342588-45342668 1.0000 80 chr17:56408795-56408875 1.0000 80 chr5:118753660-118753740 1.0000 80 chr6:26234065-26234145 1.0000 80 chr6:26198412-26198492 1.0000 80 chr6:27107972-27108052 1.0000 80 chr17:17255769-17255849 1.0000 80 chr5:16528636-16528716 1.0000 80 chrX:153191242-153191322 1.0000 80 chr12:125395389-12539546 1.0000 80 chr5:137688168-137688248 1.0000 80 chr6:27100275-27100355 1.0000 80 chr7:106650745-106650825 1.0000 80 chr12:117566171-11756625 1.0000 80 chr19:49866971-49867051 1.0000 80 chr3:44690151-44690231 1.0000 80 chr5:90679001-90679081 1.0000 80 chr6:26234966-26235046 1.0000 80 chr11:65268319-65268399 1.0000 80 chr3:185632455-185632535 1.0000 80 chr22:29548758-29548838 1.0000 80 chr11:57298338-57298418 1.0000 80 chr5:137804411-137804491 1.0000 80 chr21:46493735-46493815 1.0000 80 chr14:51135329-51135409 1.0000 80 chr6:26201850-26201930 1.0000 80 chr1:36046790-36046870 1.0000 80 chr6:33388965-33389045 1.0000 80 chr3:112360003-112360083 1.0000 80 chr6:27109233-27109313 1.0000 80 chr17:25406642-25406722 1.0000 80 chr4:1722945-1723025 1.0000 80 chr5:102455865-102455945 1.0000 80 chr1:149215102-149215182 1.0000 80 chr1:149982663-149982743 1.0000 80 chr1:17222652-17222732 1.0000 80 chr1:147735878-147735958 1.0000 80 chr6:27115318-27115398 1.0000 80 chr19:9879348-9879428 1.0000 80 chr1:150548493-150548573 1.0000 80 chr6:26157218-26157298 1.0000 80 chr6:147208040-147208120 1.0000 80 chr6:26157641-26157721 1.0000 80 chr17:30771402-30771482 1.0000 80 chr15:88120231-88120311 1.0000 80 chr1:40506419-40506499 1.0000 80 chr5:137801308-137801388 1.0000 80 chr17:57915331-57915411 1.0000 80 chr13:108870781-10887086 1.0000 80 chr11:65270702-65270782 1.0000 80 chr15:56538296-56538376 1.0000 80 chr7:32697737-32697817 1.0000 80 chr10:13628892-13628972 1.0000 80 chr9:140149717-140149797 1.0000 80 chr10:16933961-16934041 1.0000 80 chr12:121124600-12112468 1.0000 80 chr17:17991136-17991216 1.0000 80 chr3:177002378-177002458 1.0000 80 chr2:232651076-232651156 1.0000 80 chr9:114393453-114393533 1.0000 80 chr15:40675119-40675199 1.0000 80 chr2:224822101-224822181 1.0000 80 chr2:233415314-233415394 1.0000 80 chr6:27792828-27792908 1.0000 80 chr1:160695999-160696079 1.0000 80 chr20:62259778-62259858 1.0000 80 chr10:122610751-12261083 1.0000 80 chr4:142252881-142252961 1.0000 80 chrX:16789843-16789923 1.0000 80 chr7:102988041-102988121 1.0000 80 chr6:75994596-75994676 1.0000 80 chr5:180288228-180288308 1.0000 80 chr16:67906922-67907002 1.0000 80 chr20:40322141-40322221 1.0000 80 chr17:41445351-41445431 1.0000 80 chr19:56154903-56154983 1.0000 80 chr17:48785259-48785339 1.0000 80 chr3:50264973-50265053 1.0000 80 chr22:22889316-22889396 1.0000 80 chr11:65269624-65269704 1.0000 80 chr19:489005-489085 1.0000 80 chr4:73433609-73433689 1.0000 80 chr1:200610123-200610203 1.0000 80 chr9:140317624-140317704 1.0000 80 chr16:31085656-31085736 1.0000 80 chr14:74353514-74353594 1.0000 80 chr11:31391317-31391397 1.0000 80 chr12:7053031-7053111 1.0000 80 chr6:170893691-170893771 1.0000 80 chr6:28688273-28688353 1.0000 80 chr1:109935683-109935763 1.0000 80 chr15:45019334-45019414 1.0000 80 chr17:45253985-45254065 1.0000 80 chr2:197664425-197664505 1.0000 80 chr3:149470299-149470379 1.0000 80 chr20:31989349-31989429 1.0000 80 chr6:135514099-135514179 1.0000 80 chr2:68785893-68785973 1.0000 80 chr2:70121047-70121127 1.0000 80 chr19:49262476-49262556 1.0000 80 chr11:28131801-28131881 1.0000 80 chr2:232646280-232646360 1.0000 80 chr19:50083887-50083967 1.0000 80 chr6:16266961-16267041 1.0000 80 chr17:80170708-80170788 1.0000 80 chr6:28072465-28072545 1.0000 80 chr16:9085968-9086048 1.0000 80 chr9:128003468-128003548 1.0000 80 chr2:113808548-113808628 1.0000 80 chr22:22089928-22090008 1.0000 80 chr6:41747702-41747782 1.0000 80 chr3:127842783-127842863 1.0000 80 chr15:74833268-74833348 1.0000 80 chr11:65193783-65193863 1.0000 80 chr8:144897961-144898041 1.0000 80 chr3:194992407-194992487 1.0000 80 chr19:50879560-50879640 1.0000 80 chr6:26216671-26216751 1.0000 80 chr12:106751489-10675156 1.0000 80 chr19:12903461-12903541 1.0000 80 chr19:8617776-8617856 1.0000 80 chrX:119077721-119077801 1.0000 80 chr19:14682910-14682990 1.0000 80 chr6:26124451-26124531 1.0000 80 chr18:33552551-33552631 1.0000 80 chr6:28220021-28220101 1.0000 80 chr2:191137173-191137253 1.0000 80 chr5:43484459-43484539 1.0000 80 chr1:28832600-28832680 1.0000 80 chr11:46958164-46958244 1.0000 80 chr15:74908006-74908086 1.0000 80 chr19:11039394-11039474 1.0000 80 chr3:193660504-193660584 1.0000 80 chr11:59578239-59578319 1.0000 80 chr9:35812272-35812352 1.0000 80 chr5:173285455-173285535 1.0000 80 chr6:26199344-26199424 1.0000 80 chr10:27793108-27793188 1.0000 80 chr10:14227634-14227714 1.0000 80 chr14:20811435-20811515 1.0000 80 chr3:50606792-50606872 1.0000 80 chr2:242041766-242041846 1.0000 80 chr5:94982663-94982743 1.0000 80 chr15:35261965-35262045 1.0000 80 chr8:56685946-56686026 1.0000 80 chr7:5465548-5465628 1.0000 80 chr15:90358433-90358513 1.0000 80 chr6:26197486-26197566 1.0000 80 chr19:2819765-2819845 1.0000 80 chr10:74870164-74870244 1.0000 80 chr11:77790928-77791008 1.0000 80 chr8:71520639-71520719 1.0000 80 chr17:56405746-56405826 1.0000 80 chr13:41345388-41345468 1.0000 80 chr17:39834856-39834936 1.0000 80 chr12:49555395-49555475 1.0000 80 chr1:46153776-46153856 1.0000 80 chr2:61244328-61244408 1.0000 80 chr6:26056448-26056528 1.0000 80 chr1:28837549-28837629 1.0000 80 chr1:245725247-245725327 1.0000 80 chr1:145382300-145382380 1.0000 80 chr1:78470079-78470159 1.0000 80 chr14:56683905-56683985 1.0000 80 chr14:58894244-58894324 1.0000 80 chr19:2740191-2740271 1.0000 80 chr12:108999916-10899999 1.0000 80 chr21:27107278-27107358 1.0000 80 chr16:2892705-2892785 1.0000 80 chr1:76251957-76252037 1.0000 80 chr7:75831146-75831226 1.0000 80 chr11:65274304-65274384 1.0000 80 chr3:25634045-25634125 1.0000 80 chr17:56407034-56407114 1.0000 80 chr15:76196158-76196238 1.0000 80 chr1:224580483-224580563 1.0000 80 chr8:144363837-144363917 1.0000 80 chr1:11322854-11322934 1.0000 80 chr17:40925399-40925479 1.0000 80 chr6:133120278-133120358 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_BCLAF1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/BCLAF1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.232 C 0.258 G 0.281 T 0.229 Background letter frequencies (from file dataset with add-one prior applied): A 0.232 C 0.258 G 0.281 T 0.229 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CCGGAAGY MEME-1 width = 8 sites = 37 llr = 327 E-value = 5.1e-013 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCGGAAGY MEME-1 Description -------------------------------------------------------------------------------- Simplified A :2::aa:1 pos.-specific C 98::::13 probability G 1:aa::91 matrix T :::::::6 bits 2.1 ** 1.9 **** 1.7 **** 1.5 * ***** Relative 1.3 ******* Entropy 1.1 ******* (12.8 bits) 0.8 ******* 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCGGAAGT consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGGAAGY MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:40925399-40925479 49 1.82e-05 GAAGCGAAGG CCGGAAGT CCTTAGCCGG chr15:76196158-76196238 36 1.82e-05 CCCCGTCCAG CCGGAAGT GGCGCGGACG chr15:35261965-35262045 55 1.82e-05 TGGCGTGTAG CCGGAAGT TCATGCAGGC chr11:59578239-59578319 12 1.82e-05 CTCAGTGGGG CCGGAAGT TGTGTTCACT chr2:70121047-70121127 27 1.82e-05 CCCGGCCCTC CCGGAAGT TGTTGCACAG chr16:67906922-67907002 51 1.82e-05 CTCGTGGGTG CCGGAAGT GGAGGCGGTT chr2:233415314-233415394 37 1.82e-05 CCGCGCAAAA CCGGAAGT ACCCGGGCCC chr15:40675119-40675199 10 1.82e-05 GCCTAGCTA CCGGAAGT TTCTATTTGA chr13:108870781-10887086 52 1.82e-05 CGAGCGGGGG CCGGAAGT GGGGCCACAG chr1:155112995-155113075 18 1.82e-05 ATGTTGGCGT CCGGAAGT CCTCCCTGGT chr12:123459193-12345927 26 1.82e-05 GGGAACGCCA CCGGAAGT AATGCGAGAC chr8:144363837-144363917 31 3.87e-05 gaggaaaaaa ccggaagc aaaccggaaa chr18:33552551-33552631 29 3.87e-05 GTGCCTGTTT CCGGAAGC AGCTTGAGTC chr7:102988041-102988121 58 3.87e-05 GAAGACACCA CCGGAAGC AAGGAAGGTG chr9:114393453-114393533 37 3.87e-05 CAGTGACACA CCGGAAGC AGCCTAGTGG chr10:13628892-13628972 55 3.87e-05 CCAGCTTCCG CCGGAAGC GGCTCCTGTC chr7:32697737-32697817 46 3.87e-05 TGAGCTGTGC CCGGAAGC ACTGCAGCAG chr1:40506419-40506499 3 3.87e-05 TG CCGGAAGC GGAGAGCGGC chr3:44690151-44690231 48 3.87e-05 ACTTGGGGAG CCGGAAGC CCATCCCGAG chr19:56092291-56092371 60 3.87e-05 GGCTGGGAAG CCGGAAGC GGGAGGACGG chr1:46153776-46153856 51 5.51e-05 TTTCAGCCCT CAGGAAGT AGGGGCCTCT chr6:28220021-28220101 33 5.51e-05 GGCTGGGGCA CAGGAAGT CTCGATGGGA chr6:26234065-26234145 7 5.51e-05 TGTGCT CAGGAAGT CACCTCAACG chr5:118753660-118753740 54 5.51e-05 GGGTTGTGAA CAGGAAGT TGGAAGACTG chr14:74353514-74353594 36 7.35e-05 CCGGCGGGAG CCGGAAGA CGCTGTGTGT chr3:50264973-50265053 36 7.35e-05 TAGAGAGGCC CCGGAAGA GGCGGTGCAG chr5:180288228-180288308 51 7.35e-05 GACCGCACGG CCGGAAGA ACCCGCGCCG chr15:74833268-74833348 30 9.34e-05 TCAACTCCCC GCGGAAGT GCTCACACCG chr19:50083887-50083967 18 9.34e-05 GCCCCTAGTT GCGGAAGT GCCTCGCCTG chr16:31085656-31085736 36 9.34e-05 TGCTCCCGAA GCGGAAGT TTCGCGGGGA chr9:140149717-140149797 50 9.34e-05 gcggtgcggg gcggaagt gggcggctgc chr21:27107278-27107358 26 1.12e-04 GCTCACCGGA CAGGAAGC GTCTCGGAGA chrX:119077721-119077801 29 1.12e-04 TCGTCACCGA CAGGAAGC GATGTGTGCA chr6:28072465-28072545 68 1.34e-04 GGGCGCAAGG CCGGAAGG GGTTC chr6:170893691-170893771 45 1.34e-04 GGGCGCCGGG CCGGAAGG CAAGAGGCGG chr15:74908006-74908086 1 1.51e-04 . CCGGAACT AGTCTCCTAG chr11:46958164-46958244 23 1.51e-04 GCGACTGCCC CCGGAACT TGAGTGGCCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGGAAGY MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:40925399-40925479 1.8e-05 48_[+1]_24 chr15:76196158-76196238 1.8e-05 35_[+1]_37 chr15:35261965-35262045 1.8e-05 54_[+1]_18 chr11:59578239-59578319 1.8e-05 11_[+1]_61 chr2:70121047-70121127 1.8e-05 26_[+1]_46 chr16:67906922-67907002 1.8e-05 50_[+1]_22 chr2:233415314-233415394 1.8e-05 36_[+1]_36 chr15:40675119-40675199 1.8e-05 9_[+1]_63 chr13:108870781-10887086 1.8e-05 51_[+1]_21 chr1:155112995-155113075 1.8e-05 17_[+1]_55 chr12:123459193-12345927 1.8e-05 25_[+1]_47 chr8:144363837-144363917 3.9e-05 30_[+1]_42 chr18:33552551-33552631 3.9e-05 28_[+1]_44 chr7:102988041-102988121 3.9e-05 57_[+1]_15 chr9:114393453-114393533 3.9e-05 36_[+1]_36 chr10:13628892-13628972 3.9e-05 54_[+1]_18 chr7:32697737-32697817 3.9e-05 45_[+1]_27 chr1:40506419-40506499 3.9e-05 2_[+1]_70 chr3:44690151-44690231 3.9e-05 47_[+1]_25 chr19:56092291-56092371 3.9e-05 59_[+1]_13 chr1:46153776-46153856 5.5e-05 50_[+1]_22 chr6:28220021-28220101 5.5e-05 32_[+1]_40 chr6:26234065-26234145 5.5e-05 6_[+1]_66 chr5:118753660-118753740 5.5e-05 53_[+1]_19 chr14:74353514-74353594 7.4e-05 35_[+1]_37 chr3:50264973-50265053 7.4e-05 35_[+1]_37 chr5:180288228-180288308 7.4e-05 50_[+1]_22 chr15:74833268-74833348 9.3e-05 29_[+1]_43 chr19:50083887-50083967 9.3e-05 17_[+1]_55 chr16:31085656-31085736 9.3e-05 35_[+1]_37 chr9:140149717-140149797 9.3e-05 49_[+1]_23 chr21:27107278-27107358 0.00011 25_[+1]_47 chrX:119077721-119077801 0.00011 28_[+1]_44 chr6:28072465-28072545 0.00013 67_[+1]_5 chr6:170893691-170893771 0.00013 44_[+1]_28 chr15:74908006-74908086 0.00015 [+1]_72 chr11:46958164-46958244 0.00015 22_[+1]_50 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGGAAGY MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCGGAAGY width=8 seqs=37 chr17:40925399-40925479 ( 49) CCGGAAGT 1 chr15:76196158-76196238 ( 36) CCGGAAGT 1 chr15:35261965-35262045 ( 55) CCGGAAGT 1 chr11:59578239-59578319 ( 12) CCGGAAGT 1 chr2:70121047-70121127 ( 27) CCGGAAGT 1 chr16:67906922-67907002 ( 51) CCGGAAGT 1 chr2:233415314-233415394 ( 37) CCGGAAGT 1 chr15:40675119-40675199 ( 10) CCGGAAGT 1 chr13:108870781-10887086 ( 52) CCGGAAGT 1 chr1:155112995-155113075 ( 18) CCGGAAGT 1 chr12:123459193-12345927 ( 26) CCGGAAGT 1 chr8:144363837-144363917 ( 31) CCGGAAGC 1 chr18:33552551-33552631 ( 29) CCGGAAGC 1 chr7:102988041-102988121 ( 58) CCGGAAGC 1 chr9:114393453-114393533 ( 37) CCGGAAGC 1 chr10:13628892-13628972 ( 55) CCGGAAGC 1 chr7:32697737-32697817 ( 46) CCGGAAGC 1 chr1:40506419-40506499 ( 3) CCGGAAGC 1 chr3:44690151-44690231 ( 48) CCGGAAGC 1 chr19:56092291-56092371 ( 60) CCGGAAGC 1 chr1:46153776-46153856 ( 51) CAGGAAGT 1 chr6:28220021-28220101 ( 33) CAGGAAGT 1 chr6:26234065-26234145 ( 7) CAGGAAGT 1 chr5:118753660-118753740 ( 54) CAGGAAGT 1 chr14:74353514-74353594 ( 36) CCGGAAGA 1 chr3:50264973-50265053 ( 36) CCGGAAGA 1 chr5:180288228-180288308 ( 51) CCGGAAGA 1 chr15:74833268-74833348 ( 30) GCGGAAGT 1 chr19:50083887-50083967 ( 18) GCGGAAGT 1 chr16:31085656-31085736 ( 36) GCGGAAGT 1 chr9:140149717-140149797 ( 50) GCGGAAGT 1 chr21:27107278-27107358 ( 26) CAGGAAGC 1 chrX:119077721-119077801 ( 29) CAGGAAGC 1 chr6:28072465-28072545 ( 68) CCGGAAGG 1 chr6:170893691-170893771 ( 45) CCGGAAGG 1 chr15:74908006-74908086 ( 1) CCGGAACT 1 chr11:46958164-46958244 ( 23) CCGGAACT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGGAAGY MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.3679 E= 5.1e-013 -1185 179 -138 -1185 -52 170 -1185 -1185 -1185 -1185 183 -1185 -1185 -1185 183 -1185 211 -1185 -1185 -1185 211 -1185 -1185 -1185 -1185 -225 175 -1185 -151 21 -238 131 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGGAAGY MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 37 E= 5.1e-013 0.000000 0.891892 0.108108 0.000000 0.162162 0.837838 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.054054 0.945946 0.000000 0.081081 0.297297 0.054054 0.567568 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCGGAAGY MEME-1 regular expression -------------------------------------------------------------------------------- CCGGAAG[TC] -------------------------------------------------------------------------------- Time 4.80 secs. ******************************************************************************** ******************************************************************************** MOTIF TYTCTTYT MEME-2 width = 8 sites = 24 llr = 216 E-value = 1.1e-001 ******************************************************************************** -------------------------------------------------------------------------------- Motif TYTCTTYT MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C :516::4: probability G :::1:::: matrix T a593aa6a bits 2.1 * ** * 1.9 * ** * 1.7 * * ** * 1.5 * * ** * Relative 1.3 * * ** * Entropy 1.1 *** **** (13.0 bits) 0.8 *** **** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTTCTTTT consensus C T C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYTCTTYT MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:36046790-36046870 48 8.52e-06 cagcagtttg tttctttt tattgcttca chr5:137804411-137804491 61 8.52e-06 TGGTTTGGTT TTTCTTTT TTTTTTTTTT chr17:41393322-41393402 24 8.52e-06 GTGTGCGTTC TTTCTTTT TGTTTCTGAG chr6:3939328-3939408 39 8.52e-06 TTAACATTAG TTTCTTTT CCTTCTTTGT chr19:8617776-8617856 69 1.81e-05 AATGGGGGAC TCTCTTTT GAAA chr11:65268319-65268399 67 1.81e-05 GTTGTAGGTT TCTCTTTT TCAGGC chrX:153191242-153191322 50 1.81e-05 TGCATCTGGC TCTCTTTT ACCAGCGGCC chr16:67906922-67907002 4 2.77e-05 ACC TTTCTTCT CCGGCCCTGG chr6:26194647-26194727 43 2.77e-05 ATCACTCCAT TTTCTTCT CATATCGAAC chr6:37465174-37465254 68 2.77e-05 aaaaacctgt tttcttct acaac chr6:28188568-28188648 24 2.77e-05 taaaacatag tttcttct ttaaatgaaa chr19:50083887-50083967 50 3.85e-05 GCTCAAGTCC TCTCTTCT CTTTCTCTCT chr10:16933961-16934041 65 3.85e-05 TCCAAACACA TCTCTTCT CAAGGATA chr1:46153776-46153856 36 4.61e-05 CCCGGACTCA TTTTTTTT CAGCCCTCAG chr1:17222652-17222732 31 5.46e-05 AAGGGTCATA TCTTTTTT TGTTTTGGTT chr1:210547450-210547530 27 5.46e-05 CCTCTTTAAG TCTTTTTT TATAAAACAT chr5:173285455-173285535 50 6.31e-05 cctcacatta ttttttct taaatacagc chr17:39834856-39834936 72 7.27e-05 tcatgagtaa tcttttct t chr1:40363001-40363081 67 7.27e-05 GGTATGCAAT TCTTTTCT GCAACT chr3:25634045-25634125 32 8.20e-05 GCATTTTTAG TTTGTTTT GCTCTGAGTG chr1:90461681-90461761 23 8.20e-05 GGTCTTCACT TTTGTTTT CAAACCTTGC chr20:31989349-31989429 30 1.24e-04 ACGGAAGTGC TTCCTTTT TACAGTCCGG chr7:2913806-2913886 15 1.24e-04 CTTTATCTAC TCTGTTCT GTGTGGGGGT chr8:125827797-125827877 8 1.35e-04 CAAGCTA TCCCTTTT AAGCATTATC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYTCTTYT MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:36046790-36046870 8.5e-06 47_[+2]_25 chr5:137804411-137804491 8.5e-06 60_[+2]_12 chr17:41393322-41393402 8.5e-06 23_[+2]_49 chr6:3939328-3939408 8.5e-06 38_[+2]_34 chr19:8617776-8617856 1.8e-05 68_[+2]_4 chr11:65268319-65268399 1.8e-05 66_[+2]_6 chrX:153191242-153191322 1.8e-05 49_[+2]_23 chr16:67906922-67907002 2.8e-05 3_[+2]_69 chr6:26194647-26194727 2.8e-05 42_[+2]_30 chr6:37465174-37465254 2.8e-05 67_[+2]_5 chr6:28188568-28188648 2.8e-05 23_[+2]_49 chr19:50083887-50083967 3.9e-05 49_[+2]_23 chr10:16933961-16934041 3.9e-05 64_[+2]_8 chr1:46153776-46153856 4.6e-05 35_[+2]_37 chr1:17222652-17222732 5.5e-05 30_[+2]_42 chr1:210547450-210547530 5.5e-05 26_[+2]_46 chr5:173285455-173285535 6.3e-05 49_[+2]_23 chr17:39834856-39834936 7.3e-05 71_[+2]_1 chr1:40363001-40363081 7.3e-05 66_[+2]_6 chr3:25634045-25634125 8.2e-05 31_[+2]_41 chr1:90461681-90461761 8.2e-05 22_[+2]_50 chr20:31989349-31989429 0.00012 29_[+2]_43 chr7:2913806-2913886 0.00012 14_[+2]_58 chr8:125827797-125827877 0.00014 7_[+2]_65 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYTCTTYT MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TYTCTTYT width=8 seqs=24 chr1:36046790-36046870 ( 48) TTTCTTTT 1 chr5:137804411-137804491 ( 61) TTTCTTTT 1 chr17:41393322-41393402 ( 24) TTTCTTTT 1 chr6:3939328-3939408 ( 39) TTTCTTTT 1 chr19:8617776-8617856 ( 69) TCTCTTTT 1 chr11:65268319-65268399 ( 67) TCTCTTTT 1 chrX:153191242-153191322 ( 50) TCTCTTTT 1 chr16:67906922-67907002 ( 4) TTTCTTCT 1 chr6:26194647-26194727 ( 43) TTTCTTCT 1 chr6:37465174-37465254 ( 68) TTTCTTCT 1 chr6:28188568-28188648 ( 24) TTTCTTCT 1 chr19:50083887-50083967 ( 50) TCTCTTCT 1 chr10:16933961-16934041 ( 65) TCTCTTCT 1 chr1:46153776-46153856 ( 36) TTTTTTTT 1 chr1:17222652-17222732 ( 31) TCTTTTTT 1 chr1:210547450-210547530 ( 27) TCTTTTTT 1 chr5:173285455-173285535 ( 50) TTTTTTCT 1 chr17:39834856-39834936 ( 72) TCTTTTCT 1 chr1:40363001-40363081 ( 67) TCTTTTCT 1 chr3:25634045-25634125 ( 32) TTTGTTTT 1 chr1:90461681-90461761 ( 23) TTTGTTTT 1 chr20:31989349-31989429 ( 30) TTCCTTTT 1 chr7:2913806-2913886 ( 15) TCTGTTCT 1 chr8:125827797-125827877 ( 8) TCCCTTTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYTCTTYT MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.477 E= 1.1e-001 -1123 -1123 -1123 212 -1123 83 -1123 124 -1123 -163 -1123 200 -1123 128 -117 12 -1123 -1123 -1123 212 -1123 -1123 -1123 212 -1123 69 -1123 135 -1123 -1123 -1123 212 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYTCTTYT MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 24 E= 1.1e-001 0.000000 0.000000 0.000000 1.000000 0.000000 0.458333 0.000000 0.541667 0.000000 0.083333 0.000000 0.916667 0.000000 0.625000 0.125000 0.250000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.416667 0.000000 0.583333 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TYTCTTYT MEME-2 regular expression -------------------------------------------------------------------------------- T[TC]T[CT]TT[TC]T -------------------------------------------------------------------------------- Time 8.46 secs. ******************************************************************************** ******************************************************************************** MOTIF RCTTCCKG MEME-3 width = 8 sites = 30 llr = 255 E-value = 8.9e-001 ******************************************************************************** -------------------------------------------------------------------------------- Motif RCTTCCKG MEME-3 Description -------------------------------------------------------------------------------- Simplified A 5:::::1: pos.-specific C :8::8a:: probability G 52::::5a matrix T ::aa2:4: bits 2.1 ** 1.9 ** * * 1.7 ** * * 1.5 ** * * Relative 1.3 ***** * Entropy 1.1 ****** * (12.3 bits) 0.8 ****** * 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ACTTCCGG consensus GG T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTTCCKG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:2892705-2892785 34 1.65e-05 GGTTCGCTAA ACTTCCGG TGGGCTCCAA chr8:56685946-56686026 59 1.65e-05 CCTCGGAGCC ACTTCCGG CGGCAGCGTC chr19:11039394-11039474 3 1.65e-05 CC ACTTCCGG TAAAGTTGGC chr19:50879560-50879640 53 1.65e-05 TACCCGGTAA ACTTCCGG TGAGTTTCCA chr11:31391317-31391397 61 1.65e-05 CGGAACAGTG ACTTCCGG CGGAAGAAGA chr7:102988041-102988121 25 1.65e-05 AGCCCAATTT ACTTCCGG TGGGGAAGGG chr8:143751396-143751476 41 1.65e-05 TCCCCCAGCT ACTTCCGG GACGCTCTAG chr6:28220021-28220101 60 2.99e-05 AACTAAGGCC ACTTCCTG GGCGCTCTAG chr16:31085656-31085736 73 2.99e-05 ACCTAAGGAC ACTTCCTG chr3:44690151-44690231 68 2.99e-05 ATCCCGAGGC ACTTCCTG TCCGG chr2:171786925-171787005 45 2.99e-05 AAGAGAGTGC ACTTCCTG GTGCTACCTT chr17:40925399-40925479 69 4.99e-05 TTAGCCGGTA GCTTCCGG GTTT chr14:74353514-74353594 22 4.99e-05 CGCTCGAGCT GCTTCCGG CGGGAGCCGG chr3:50264973-50265053 68 4.99e-05 CCCCGAGGCC GCTTCCGG CTTCG chr2:232651076-232651156 28 4.99e-05 GCGGTGGGAG GCTTCCGG GGGAGCTGCA chr3:127842783-127842863 34 6.62e-05 CGTAGCCGGC GCTTCCTG CCGAGGCTGG chr1:36866739-36866819 68 6.62e-05 cccagccacc gcttcctg tcatg chr11:77790928-77791008 54 8.42e-05 CGGCACGCGA AGTTCCGG GCTACTAAGT chr1:78470079-78470159 24 1.25e-04 TAGTACACAA ACTTTCTG GCGTTTCTGA chr6:26194647-26194727 23 1.25e-04 CAGTTAATTC ACTTTCTG CCATCACTCC chr19:2740191-2740271 55 1.47e-04 GGCGAGGAAC GGTTCCGG CAGGGTTGGG chr3:149470299-149470379 41 1.47e-04 CGGAGCTTTG GGTTCCGG CCTACGAACT chr16:67906922-67907002 24 1.47e-04 GGCCCTGGCA GGTTCCGG GAGCCTCGGC chr2:224822101-224822181 13 1.47e-04 CCGCGTTCCG GGTTCCGG GGGAAGTGTG chr22:29548758-29548838 48 1.83e-04 gtgccccatg ggttcctg gcttgaagca chr15:45019334-45019414 60 2.11e-04 AACTGCTTTT ACTTCCAG TGGTTCTTTA chr1:149982663-149982743 14 2.11e-04 AGGATCGGTG GCTTTCTG CTGTCCGGCC chr17:17255769-17255849 31 2.11e-04 GATTAAGTTT ACTTCCAG CATTTGGGTC chr5:77074985-77075065 26 2.11e-04 gatggggact gctttctg gcaacaggcc chr1:207779253-207779333 25 2.11e-04 GTTCCCTTTA GCTTTCTG TCACTGTTTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTTCCKG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:2892705-2892785 1.6e-05 33_[+3]_39 chr8:56685946-56686026 1.6e-05 58_[+3]_14 chr19:11039394-11039474 1.6e-05 2_[+3]_70 chr19:50879560-50879640 1.6e-05 52_[+3]_20 chr11:31391317-31391397 1.6e-05 60_[+3]_12 chr7:102988041-102988121 1.6e-05 24_[+3]_48 chr8:143751396-143751476 1.6e-05 40_[+3]_32 chr6:28220021-28220101 3e-05 59_[+3]_13 chr16:31085656-31085736 3e-05 72_[+3] chr3:44690151-44690231 3e-05 67_[+3]_5 chr2:171786925-171787005 3e-05 44_[+3]_28 chr17:40925399-40925479 5e-05 68_[+3]_4 chr14:74353514-74353594 5e-05 21_[+3]_51 chr3:50264973-50265053 5e-05 67_[+3]_5 chr2:232651076-232651156 5e-05 27_[+3]_45 chr3:127842783-127842863 6.6e-05 33_[+3]_39 chr1:36866739-36866819 6.6e-05 67_[+3]_5 chr11:77790928-77791008 8.4e-05 53_[+3]_19 chr1:78470079-78470159 0.00013 23_[+3]_49 chr6:26194647-26194727 0.00013 22_[+3]_50 chr19:2740191-2740271 0.00015 54_[+3]_18 chr3:149470299-149470379 0.00015 40_[+3]_32 chr16:67906922-67907002 0.00015 23_[+3]_49 chr2:224822101-224822181 0.00015 12_[+3]_60 chr22:29548758-29548838 0.00018 47_[+3]_25 chr15:45019334-45019414 0.00021 59_[+3]_13 chr1:149982663-149982743 0.00021 13_[+3]_59 chr17:17255769-17255849 0.00021 30_[+3]_42 chr5:77074985-77075065 0.00021 25_[+3]_47 chr1:207779253-207779333 0.00021 24_[+3]_48 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTTCCKG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF RCTTCCKG width=8 seqs=30 chr16:2892705-2892785 ( 34) ACTTCCGG 1 chr8:56685946-56686026 ( 59) ACTTCCGG 1 chr19:11039394-11039474 ( 3) ACTTCCGG 1 chr19:50879560-50879640 ( 53) ACTTCCGG 1 chr11:31391317-31391397 ( 61) ACTTCCGG 1 chr7:102988041-102988121 ( 25) ACTTCCGG 1 chr8:143751396-143751476 ( 41) ACTTCCGG 1 chr6:28220021-28220101 ( 60) ACTTCCTG 1 chr16:31085656-31085736 ( 73) ACTTCCTG 1 chr3:44690151-44690231 ( 68) ACTTCCTG 1 chr2:171786925-171787005 ( 45) ACTTCCTG 1 chr17:40925399-40925479 ( 69) GCTTCCGG 1 chr14:74353514-74353594 ( 22) GCTTCCGG 1 chr3:50264973-50265053 ( 68) GCTTCCGG 1 chr2:232651076-232651156 ( 28) GCTTCCGG 1 chr3:127842783-127842863 ( 34) GCTTCCTG 1 chr1:36866739-36866819 ( 68) GCTTCCTG 1 chr11:77790928-77791008 ( 54) AGTTCCGG 1 chr1:78470079-78470159 ( 24) ACTTTCTG 1 chr6:26194647-26194727 ( 23) ACTTTCTG 1 chr19:2740191-2740271 ( 55) GGTTCCGG 1 chr3:149470299-149470379 ( 41) GGTTCCGG 1 chr16:67906922-67907002 ( 24) GGTTCCGG 1 chr2:224822101-224822181 ( 13) GGTTCCGG 1 chr22:29548758-29548838 ( 48) GGTTCCTG 1 chr15:45019334-45019414 ( 60) ACTTCCAG 1 chr1:149982663-149982743 ( 14) GCTTTCTG 1 chr17:17255769-17255849 ( 31) ACTTCCAG 1 chr5:77074985-77075065 ( 26) GCTTTCTG 1 chr1:207779253-207779333 ( 25) GCTTTCTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTTCCKG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.5224 E= 8.9e-001 120 -1155 73 -1155 -1155 163 -49 -1155 -1155 -1155 -1155 212 -1155 -1155 -1155 212 -1155 169 -1155 -46 -1155 196 -1155 -1155 -180 -1155 92 80 -1155 -1155 183 -1155 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTTCCKG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 30 E= 8.9e-001 0.533333 0.000000 0.466667 0.000000 0.000000 0.800000 0.200000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.833333 0.000000 0.166667 0.000000 1.000000 0.000000 0.000000 0.066667 0.000000 0.533333 0.400000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif RCTTCCKG MEME-3 regular expression -------------------------------------------------------------------------------- [AG][CG]TTCC[GT]G -------------------------------------------------------------------------------- Time 12.10 secs. ******************************************************************************** ******************************************************************************** MOTIF TTGTTTCC MEME-4 width = 8 sites = 2 llr = 23 E-value = 1.7e+005 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTGTTTCC MEME-4 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C ::::::aa probability G ::a::::: matrix T aa:aaa:: bits 2.1 ** *** 1.9 ******** 1.7 ******** 1.5 ******** Relative 1.3 ******** Entropy 1.1 ******** (16.4 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTGTTTCC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTTTCC MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr14:58894244-58894324 45 1.18e-05 TGTCCGGAGT TTGTTTCC ACCCGGAGAG chr2:70121047-70121127 45 1.18e-05 TGTTGCACAG TTGTTTCC GGGAAGCGGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTTTCC MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr14:58894244-58894324 1.2e-05 44_[+4]_28 chr2:70121047-70121127 1.2e-05 44_[+4]_28 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTTTCC MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTGTTTCC width=8 seqs=2 chr14:58894244-58894324 ( 45) TTGTTTCC 1 chr2:70121047-70121127 ( 45) TTGTTTCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTTTCC MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.3073 E= 1.7e+005 -765 -765 -765 212 -765 -765 -765 212 -765 -765 183 -765 -765 -765 -765 212 -765 -765 -765 212 -765 -765 -765 212 -765 195 -765 -765 -765 195 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTTTCC MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 1.7e+005 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTGTTTCC MEME-4 regular expression -------------------------------------------------------------------------------- TTGTTTCC -------------------------------------------------------------------------------- Time 15.67 secs. ******************************************************************************** ******************************************************************************** MOTIF TGGTTTCT MEME-5 width = 8 sites = 4 llr = 45 E-value = 1.1e+005 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGGTTTCT MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C ::::::a: probability G :aa::::: matrix T a::aaa:a bits 2.1 * *** * 1.9 ******** 1.7 ******** 1.5 ******** Relative 1.3 ******** Entropy 1.1 ******** (16.2 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGGTTTCT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGTTTCT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:245725247-245725327 45 1.28e-05 CACTCTTCAG TGGTTTCT CCCAGGGCCG chr4:142252881-142252961 7 1.28e-05 TTTGAG TGGTTTCT TTGAGCAGAG chr17:57915331-57915411 61 1.28e-05 TTACAGCTCT TGGTTTCT CCCAGACATG chr14:23120401-23120481 72 1.28e-05 AGCAGGCCTG TGGTTTCT A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGTTTCT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:245725247-245725327 1.3e-05 44_[+5]_28 chr4:142252881-142252961 1.3e-05 6_[+5]_66 chr17:57915331-57915411 1.3e-05 60_[+5]_12 chr14:23120401-23120481 1.3e-05 71_[+5]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGTTTCT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGGTTTCT width=8 seqs=4 chr1:245725247-245725327 ( 45) TGGTTTCT 1 chr4:142252881-142252961 ( 7) TGGTTTCT 1 chr17:57915331-57915411 ( 61) TGGTTTCT 1 chr14:23120401-23120481 ( 72) TGGTTTCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGTTTCT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.1553 E= 1.1e+005 -865 -865 -865 212 -865 -865 183 -865 -865 -865 183 -865 -865 -865 -865 212 -865 -865 -865 212 -865 -865 -865 212 -865 195 -865 -865 -865 -865 -865 212 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGTTTCT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 4 E= 1.1e+005 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGTTTCT MEME-5 regular expression -------------------------------------------------------------------------------- TGGTTTCT -------------------------------------------------------------------------------- Time 19.22 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:61266693-61266773 6.16e-01 80 chr1:207779253-207779333 6.61e-03 80 chr2:108972836-108972916 3.27e-01 80 chr18:9014192-9014272 1.53e-01 80 chr3:129118847-129118927 1.69e-01 80 chr6:26033176-26033256 3.97e-02 80 chr6:27092342-27092422 9.14e-01 80 chr11:65192798-65192878 7.16e-03 80 chr6:27776711-27776791 7.07e-03 38_[+5(7.85e-05)]_34 chr4:38324943-38325023 6.14e-02 80 chr1:90461681-90461761 5.53e-03 22_[+2(8.20e-05)]_50 chr11:10476501-10476581 6.73e-01 80 chr2:171786925-171787005 1.05e-02 44_[+3(2.99e-05)]_28 chr17:10694341-10694421 2.81e-01 80 chr5:132002197-132002277 3.39e-01 80 chr11:120107418-12010749 7.68e-01 80 chr19:5352587-5352667 2.09e-01 80 chr2:145116776-145116856 1.00e+00 80 chr1:40363001-40363081 1.87e-03 66_[+2(7.27e-05)]_6 chr8:143751396-143751476 5.66e-02 40_[+3(1.65e-05)]_32 chr17:56743939-56744019 8.96e-01 80 chr2:108361773-108361853 1.46e-02 80 chr1:28835000-28835080 8.41e-01 80 chr6:27115989-27116069 9.11e-01 80 chr10:23344693-23344773 1.83e-01 80 chr14:23120401-23120481 1.31e-02 71_[+5(1.28e-05)]_1 chr6:3939328-3939408 1.27e-04 38_[+2(8.52e-06)]_34 chr15:75052858-75052938 1.09e-01 80 chr3:13044214-13044294 9.27e-01 80 chr6:28188568-28188648 2.75e-04 23_[+2(2.77e-05)]_49 chr11:65273319-65273399 9.23e-01 80 chr11:65274101-65274181 2.13e-02 80 chr6:27834378-27834458 7.94e-01 80 chr6:26031120-26031200 9.84e-01 80 chr11:1372908-1372988 2.05e-01 80 chr5:137803884-137803964 7.80e-03 80 chr16:2771124-2771204 2.89e-01 80 chr6:26126864-26126944 5.59e-02 80 chr12:123459193-12345927 1.38e-01 25_[+1(1.82e-05)]_47 chr6:37465174-37465254 8.41e-04 67_[+2(2.77e-05)]_5 chr20:52369772-52369852 6.45e-01 80 chr5:61561674-61561754 9.58e-01 80 chr6:26194647-26194727 3.76e-03 42_[+2(2.77e-05)]_30 chr16:57716918-57716998 7.88e-01 80 chr7:2913806-2913886 2.84e-03 48_[+5(7.85e-05)]_24 chr8:125827797-125827877 2.91e-02 80 chr19:13211029-13211109 7.88e-01 80 chr2:30884273-30884353 6.28e-01 80 chr5:77074985-77075065 4.27e-04 24_[+5(7.85e-05)]_48 chr16:30538161-30538241 9.93e-01 80 chr11:65190911-65190991 9.03e-01 80 chr11:65270501-65270581 1.54e-01 80 chr1:155112995-155113075 2.85e-02 17_[+1(1.82e-05)]_55 chr13:114103626-11410370 3.80e-01 80 chr6:15211639-15211719 6.15e-01 80 chr1:210547450-210547530 2.21e-02 26_[+2(5.46e-05)]_46 chr19:5309096-5309176 3.74e-01 80 chr12:49667262-49667342 9.44e-01 80 chr1:36866739-36866819 1.72e-02 67_[+3(6.62e-05)]_5 chr19:56092291-56092371 1.00e-01 59_[+1(3.87e-05)]_13 chr4:68441103-68441183 9.72e-01 80 chr6:15211429-15211509 4.83e-01 80 chr6:119215197-119215277 1.29e-01 80 chr2:152685351-152685431 8.34e-01 80 chr17:26421222-26421302 7.21e-02 80 chr17:57916863-57916943 9.60e-01 80 chr2:99952938-99953018 5.49e-02 80 chr17:41393322-41393402 4.46e-05 23_[+2(8.52e-06)]_49 chr6:27101649-27101729 7.35e-01 80 chr16:89160192-89160272 9.69e-01 80 chr12:45342588-45342668 1.60e-01 80 chr17:56408795-56408875 8.30e-01 80 chr5:118753660-118753740 2.72e-01 53_[+1(5.51e-05)]_19 chr6:26234065-26234145 1.35e-01 6_[+1(5.51e-05)]_66 chr6:26198412-26198492 2.34e-01 80 chr6:27107972-27108052 3.19e-01 80 chr17:17255769-17255849 9.99e-02 80 chr5:16528636-16528716 8.30e-01 80 chrX:153191242-153191322 9.65e-03 49_[+2(1.81e-05)]_23 chr12:125395389-12539546 2.28e-02 18_[+4(1.18e-05)]_54 chr5:137688168-137688248 9.83e-01 80 chr6:27100275-27100355 6.70e-01 80 chr7:106650745-106650825 9.06e-01 80 chr12:117566171-11756625 9.77e-01 80 chr19:49866971-49867051 9.96e-01 80 chr3:44690151-44690231 1.59e-03 47_[+1(3.87e-05)]_12_[+3(2.99e-05)]_\ 5 chr5:90679001-90679081 2.02e-01 80 chr6:26234966-26235046 8.82e-01 80 chr11:65268319-65268399 7.49e-04 66_[+2(1.81e-05)]_6 chr3:185632455-185632535 9.29e-01 80 chr22:29548758-29548838 1.19e-02 80 chr11:57298338-57298418 7.23e-01 80 chr5:137804411-137804491 1.69e-03 60_[+2(8.52e-06)]_[+2(4.61e-05)]_4 chr21:46493735-46493815 6.55e-01 80 chr14:51135329-51135409 1.01e-02 80 chr6:26201850-26201930 5.28e-02 80 chr1:36046790-36046870 8.60e-05 47_[+2(8.52e-06)]_25 chr6:33388965-33389045 2.33e-01 80 chr3:112360003-112360083 7.00e-01 80 chr6:27109233-27109313 6.20e-01 80 chr17:25406642-25406722 5.41e-01 80 chr4:1722945-1723025 3.15e-01 80 chr5:102455865-102455945 5.10e-01 80 chr1:149215102-149215182 8.29e-01 80 chr1:149982663-149982743 3.03e-03 80 chr1:17222652-17222732 1.09e-03 30_[+2(5.46e-05)]_42 chr1:147735878-147735958 8.99e-01 80 chr6:27115318-27115398 2.03e-03 80 chr19:9879348-9879428 9.05e-01 80 chr1:150548493-150548573 7.14e-01 80 chr6:26157218-26157298 3.19e-01 80 chr6:147208040-147208120 9.32e-01 80 chr6:26157641-26157721 2.09e-02 80 chr17:30771402-30771482 6.82e-01 80 chr15:88120231-88120311 2.13e-01 80 chr1:40506419-40506499 2.92e-01 2_[+1(3.87e-05)]_70 chr5:137801308-137801388 5.31e-01 80 chr17:57915331-57915411 6.26e-05 60_[+5(1.28e-05)]_12 chr13:108870781-10887086 1.83e-01 51_[+1(1.82e-05)]_21 chr11:65270702-65270782 1.28e-01 80 chr15:56538296-56538376 3.88e-01 80 chr7:32697737-32697817 2.68e-01 45_[+1(3.87e-05)]_27 chr10:13628892-13628972 4.78e-03 54_[+1(3.87e-05)]_18 chr9:140149717-140149797 1.12e-01 49_[+1(9.34e-05)]_23 chr10:16933961-16934041 8.67e-02 64_[+2(3.85e-05)]_8 chr12:121124600-12112468 9.93e-01 80 chr17:17991136-17991216 1.62e-01 80 chr3:177002378-177002458 7.22e-03 80 chr2:232651076-232651156 4.93e-02 27_[+3(4.99e-05)]_45 chr9:114393453-114393533 8.10e-02 36_[+1(3.87e-05)]_36 chr15:40675119-40675199 1.06e-03 9_[+1(1.82e-05)]_63 chr2:224822101-224822181 3.89e-03 80 chr2:233415314-233415394 1.71e-01 36_[+1(1.82e-05)]_36 chr6:27792828-27792908 1.32e-01 80 chr1:160695999-160696079 5.40e-01 80 chr20:62259778-62259858 3.19e-01 80 chr10:122610751-12261083 5.35e-01 80 chr4:142252881-142252961 2.48e-04 6_[+5(1.28e-05)]_66 chrX:16789843-16789923 3.42e-01 80 chr7:102988041-102988121 3.56e-04 24_[+3(1.65e-05)]_25_[+1(3.87e-05)]_\ 15 chr6:75994596-75994676 5.60e-01 80 chr5:180288228-180288308 3.22e-01 50_[+1(7.35e-05)]_22 chr16:67906922-67907002 2.70e-05 3_[+2(2.77e-05)]_39_[+1(1.82e-05)]_\ 22 chr20:40322141-40322221 5.60e-01 80 chr17:41445351-41445431 9.98e-01 80 chr19:56154903-56154983 2.46e-02 80 chr17:48785259-48785339 1.93e-01 80 chr3:50264973-50265053 1.17e-02 35_[+1(7.35e-05)]_24_[+3(4.99e-05)]_\ 5 chr22:22889316-22889396 3.06e-01 80 chr11:65269624-65269704 7.81e-01 80 chr19:489005-489085 9.98e-01 80 chr4:73433609-73433689 3.37e-01 80 chr1:200610123-200610203 2.39e-01 80 chr9:140317624-140317704 3.89e-01 80 chr16:31085656-31085736 8.56e-03 35_[+1(9.34e-05)]_29_[+3(2.99e-05)] chr14:74353514-74353594 4.04e-03 21_[+3(4.99e-05)]_6_[+1(7.35e-05)]_\ 37 chr11:31391317-31391397 8.78e-03 60_[+3(1.65e-05)]_12 chr12:7053031-7053111 2.30e-02 80 chr6:170893691-170893771 2.43e-01 80 chr6:28688273-28688353 5.52e-02 80 chr1:109935683-109935763 4.23e-01 80 chr15:45019334-45019414 1.28e-02 80 chr17:45253985-45254065 8.64e-01 80 chr2:197664425-197664505 4.88e-01 80 chr3:149470299-149470379 4.43e-02 80 chr20:31989349-31989429 2.35e-03 80 chr6:135514099-135514179 2.18e-01 80 chr2:68785893-68785973 1.80e-02 80 chr2:70121047-70121127 3.21e-05 26_[+1(1.82e-05)]_10_[+4(1.18e-05)]_\ 28 chr19:49262476-49262556 9.67e-01 80 chr11:28131801-28131881 2.82e-01 80 chr2:232646280-232646360 9.96e-01 80 chr19:50083887-50083967 8.40e-04 17_[+1(9.34e-05)]_24_[+2(3.85e-05)]_\ 23 chr6:16266961-16267041 1.00e+00 80 chr17:80170708-80170788 5.04e-01 80 chr6:28072465-28072545 4.01e-01 80 chr16:9085968-9086048 5.21e-01 80 chr9:128003468-128003548 7.37e-01 80 chr2:113808548-113808628 7.91e-01 80 chr22:22089928-22090008 8.49e-01 80 chr6:41747702-41747782 7.70e-01 80 chr3:127842783-127842863 6.04e-02 33_[+3(6.62e-05)]_39 chr15:74833268-74833348 1.05e-02 29_[+1(9.34e-05)]_43 chr11:65193783-65193863 5.61e-01 80 chr8:144897961-144898041 9.38e-01 80 chr3:194992407-194992487 9.29e-01 80 chr19:50879560-50879640 2.01e-03 52_[+3(1.65e-05)]_20 chr6:26216671-26216751 4.02e-01 80 chr12:106751489-10675156 1.08e-01 80 chr19:12903461-12903541 9.92e-01 80 chr19:8617776-8617856 1.23e-01 68_[+2(1.81e-05)]_4 chrX:119077721-119077801 4.15e-01 80 chr19:14682910-14682990 9.83e-01 80 chr6:26124451-26124531 6.07e-01 80 chr18:33552551-33552631 3.01e-03 28_[+1(3.87e-05)]_44 chr6:28220021-28220101 8.53e-03 32_[+1(5.51e-05)]_19_[+3(2.99e-05)]_\ 13 chr2:191137173-191137253 5.36e-01 80 chr5:43484459-43484539 4.55e-01 80 chr1:28832600-28832680 9.37e-01 80 chr11:46958164-46958244 1.92e-01 80 chr15:74908006-74908086 2.05e-01 80 chr19:11039394-11039474 5.70e-04 2_[+3(1.65e-05)]_70 chr3:193660504-193660584 4.49e-01 80 chr11:59578239-59578319 4.01e-02 11_[+1(1.82e-05)]_61 chr9:35812272-35812352 4.68e-01 80 chr5:173285455-173285535 2.94e-03 49_[+2(6.31e-05)]_23 chr6:26199344-26199424 6.33e-01 80 chr10:27793108-27793188 4.42e-01 80 chr10:14227634-14227714 5.06e-01 80 chr14:20811435-20811515 5.54e-01 80 chr3:50606792-50606872 6.01e-01 80 chr2:242041766-242041846 2.17e-01 80 chr5:94982663-94982743 3.28e-01 80 chr15:35261965-35262045 5.38e-02 54_[+1(1.82e-05)]_18 chr8:56685946-56686026 6.41e-02 58_[+3(1.65e-05)]_14 chr7:5465548-5465628 7.44e-01 80 chr15:90358433-90358513 2.71e-01 80 chr6:26197486-26197566 7.48e-01 80 chr19:2819765-2819845 9.69e-01 80 chr10:74870164-74870244 5.44e-01 80 chr11:77790928-77791008 9.19e-02 53_[+3(8.42e-05)]_19 chr8:71520639-71520719 5.84e-01 80 chr17:56405746-56405826 1.30e-01 80 chr13:41345388-41345468 3.90e-01 80 chr17:39834856-39834936 1.90e-02 71_[+2(7.27e-05)]_1 chr12:49555395-49555475 6.48e-01 80 chr1:46153776-46153856 3.27e-04 35_[+2(4.61e-05)]_7_[+1(5.51e-05)]_\ 22 chr2:61244328-61244408 4.61e-01 80 chr6:26056448-26056528 7.30e-02 80 chr1:28837549-28837629 4.61e-02 80 chr1:245725247-245725327 4.81e-03 44_[+5(1.28e-05)]_28 chr1:145382300-145382380 2.48e-01 80 chr1:78470079-78470159 1.89e-02 80 chr14:56683905-56683985 4.95e-01 80 chr14:58894244-58894324 3.97e-03 44_[+4(1.18e-05)]_28 chr19:2740191-2740271 1.59e-02 80 chr12:108999916-10899999 5.49e-01 80 chr21:27107278-27107358 3.92e-01 80 chr16:2892705-2892785 8.39e-03 33_[+3(1.65e-05)]_25_[+3(2.99e-05)]_\ 6 chr1:76251957-76252037 8.36e-01 80 chr7:75831146-75831226 9.99e-01 80 chr11:65274304-65274384 2.34e-01 80 chr3:25634045-25634125 5.54e-03 31_[+2(8.20e-05)]_41 chr17:56407034-56407114 7.42e-01 80 chr15:76196158-76196238 1.66e-01 35_[+1(1.82e-05)]_37 chr1:224580483-224580563 5.49e-01 80 chr8:144363837-144363917 5.17e-02 10_[+1(3.87e-05)]_12_[+1(3.87e-05)]_\ 42 chr1:11322854-11322934 3.56e-02 80 chr17:40925399-40925479 1.03e-04 48_[+1(1.82e-05)]_12_[+3(4.99e-05)]_\ 4 chr6:133120278-133120358 1.17e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n09.farnam.hpc.yale.internal ********************************************************************************