******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/ATF1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr3:52444006-52444086 1.0000 80 chr17:17380259-17380339 1.0000 80 chr5:176297160-176297240 1.0000 80 chr5:36151247-36151327 1.0000 80 chr18:21013472-21013552 1.0000 80 chr16:86588797-86588877 1.0000 80 chr5:1746732-1746812 1.0000 80 chr6:15248951-15249031 1.0000 80 chr22:26879779-26879859 1.0000 80 chr1:7831308-7831388 1.0000 80 chr16:67694742-67694822 1.0000 80 chrX:19361980-19362060 1.0000 80 chr9:71394846-71394926 1.0000 80 chr14:88851951-88852031 1.0000 80 chr17:27071370-27071450 1.0000 80 chr19:15560781-15560861 1.0000 80 chr22:39097024-39097104 1.0000 80 chr2:96068405-96068485 1.0000 80 chr22:42353796-42353876 1.0000 80 chr18:77439738-77439818 1.0000 80 chr9:6015603-6015683 1.0000 80 chr6:139456093-139456173 1.0000 80 chr18:76829199-76829279 1.0000 80 chr4:119512822-119512902 1.0000 80 chrX:152736366-152736446 1.0000 80 chr10:17428846-17428926 1.0000 80 chr11:77185396-77185476 1.0000 80 chr14:24769007-24769087 1.0000 80 chrX:11129849-11129929 1.0000 80 chr16:75589259-75589339 1.0000 80 chr2:28114116-28114196 1.0000 80 chr9:128845119-128845199 1.0000 80 chr3:120461510-120461590 1.0000 80 chr13:49821995-49822075 1.0000 80 chr4:123073408-123073488 1.0000 80 chr2:143688668-143688748 1.0000 80 chr3:183146404-183146484 1.0000 80 chr19:18747796-18747876 1.0000 80 chr20:57463855-57463935 1.0000 80 chr19:17462840-17462920 1.0000 80 chr13:45915351-45915431 1.0000 80 chr5:95297720-95297800 1.0000 80 chr12:58138358-58138438 1.0000 80 chr13:45492495-45492575 1.0000 80 chr3:123442586-123442666 1.0000 80 chr17:4046928-4047008 1.0000 80 chr2:110962574-110962654 1.0000 80 chr1:224180314-224180394 1.0000 80 chr12:39932515-39932595 1.0000 80 chr10:113943489-11394356 1.0000 80 chr17:8152575-8152655 1.0000 80 chr14:100150213-10015029 1.0000 80 chr2:19548159-19548239 1.0000 80 chr14:55738807-55738887 1.0000 80 chr14:99947697-99947777 1.0000 80 chr7:45808638-45808718 1.0000 80 chr16:67927106-67927186 1.0000 80 chr8:42195584-42195664 1.0000 80 chr1:85155993-85156073 1.0000 80 chr19:29704079-29704159 1.0000 80 chr17:79093580-79093660 1.0000 80 chr9:102582448-102582528 1.0000 80 chr7:30174271-30174351 1.0000 80 chr10:124740124-12474020 1.0000 80 chr17:49198364-49198444 1.0000 80 chr7:23145292-23145372 1.0000 80 chr22:50683422-50683502 1.0000 80 chr9:99179703-99179783 1.0000 80 chr19:50979505-50979585 1.0000 80 chr2:240964754-240964834 1.0000 80 chr2:190305778-190305858 1.0000 80 chrX:133941136-133941216 1.0000 80 chr1:2343987-2344067 1.0000 80 chr6:160941293-160941373 1.0000 80 chr10:116697928-11669800 1.0000 80 chr14:36789851-36789931 1.0000 80 chr17:56709450-56709530 1.0000 80 chr22:29866517-29866597 1.0000 80 chr21:44394642-44394722 1.0000 80 chr4:148605328-148605408 1.0000 80 chr14:71067346-71067426 1.0000 80 chr11:16626065-16626145 1.0000 80 chr14:32030564-32030644 1.0000 80 chr6:167880211-167880291 1.0000 80 chr19:1042336-1042416 1.0000 80 chr6:34664699-34664779 1.0000 80 chr12:131249962-13125004 1.0000 80 chr8:17104332-17104412 1.0000 80 chr20:3801390-3801470 1.0000 80 chr14:61447791-61447871 1.0000 80 chr19:46135958-46136038 1.0000 80 chr17:4607408-4607488 1.0000 80 chr3:48488031-48488111 1.0000 80 chr8:37605543-37605623 1.0000 80 chr3:160282833-160282913 1.0000 80 chr2:74781531-74781611 1.0000 80 chr13:101327228-10132730 1.0000 80 chr8:42195945-42196025 1.0000 80 chr12:64616330-64616410 1.0000 80 chr2:237994474-237994554 1.0000 80 chrX:102809840-102809920 1.0000 80 chr1:156698616-156698696 1.0000 80 chr11:63706251-63706331 1.0000 80 chr18:5296892-5296972 1.0000 80 chr3:184053650-184053730 1.0000 80 chr1:236030340-236030420 1.0000 80 chr19:51373827-51373907 1.0000 80 chr19:50862210-50862290 1.0000 80 chr2:68290122-68290202 1.0000 80 chr5:43121577-43121657 1.0000 80 chr8:142726252-142726332 1.0000 80 chr2:202507410-202507490 1.0000 80 chr1:19181216-19181296 1.0000 80 chrX:347676-347756 1.0000 80 chrX:102024032-102024112 1.0000 80 chr10:102027391-10202747 1.0000 80 chr5:1345260-1345340 1.0000 80 chr19:36103592-36103672 1.0000 80 chr9:32573124-32573204 1.0000 80 chr9:134955265-134955345 1.0000 80 chr9:139760857-139760937 1.0000 80 chr22:32058199-32058279 1.0000 80 chr14:23775929-23776009 1.0000 80 chr1:153395105-153395185 1.0000 80 chr12:131249285-13124936 1.0000 80 chr19:1885483-1885563 1.0000 80 chr20:4202284-4202364 1.0000 80 chr3:51533991-51534071 1.0000 80 chr7:5553407-5553487 1.0000 80 chr9:102584029-102584109 1.0000 80 chr12:15501607-15501687 1.0000 80 chr7:30978493-30978573 1.0000 80 chr1:230760013-230760093 1.0000 80 chr1:47644864-47644944 1.0000 80 chr3:53164430-53164510 1.0000 80 chrX:149106786-149106866 1.0000 80 chr1:85742219-85742299 1.0000 80 chr8:92082231-92082311 1.0000 80 chr19:17728353-17728433 1.0000 80 chr7:102036788-102036868 1.0000 80 chr19:7627866-7627946 1.0000 80 chr7:56019533-56019613 1.0000 80 chr13:77566192-77566272 1.0000 80 chr12:498741-498821 1.0000 80 chr1:154600433-154600513 1.0000 80 chr13:103249182-10324926 1.0000 80 chr14:50235317-50235397 1.0000 80 chr17:1953733-1953813 1.0000 80 chr19:9649284-9649364 1.0000 80 chr1:70671284-70671364 1.0000 80 chr10:104159404-10415948 1.0000 80 chr11:506841-506921 1.0000 80 chr19:54975953-54976033 1.0000 80 chr18:77748569-77748649 1.0000 80 chr1:156698223-156698303 1.0000 80 chr21:43430421-43430501 1.0000 80 chr16:71879813-71879893 1.0000 80 chr5:6713298-6713378 1.0000 80 chr9:139377510-139377590 1.0000 80 chr2:202316204-202316284 1.0000 80 chr9:129568208-129568288 1.0000 80 chr5:72861526-72861606 1.0000 80 chr4:1714783-1714863 1.0000 80 chr8:145743311-145743391 1.0000 80 chr14:104095424-10409550 1.0000 80 chr9:99382149-99382229 1.0000 80 chr16:58283811-58283891 1.0000 80 chr14:105219421-10521950 1.0000 80 chr3:51428570-51428650 1.0000 80 chr19:55987892-55987972 1.0000 80 chr2:30670058-30670138 1.0000 80 chr9:37465408-37465488 1.0000 80 chr1:243418392-243418472 1.0000 80 chr15:29561995-29562075 1.0000 80 chr12:42719907-42719987 1.0000 80 chr1:4052251-4052331 1.0000 80 chr2:153191505-153191585 1.0000 80 chr6:52463157-52463237 1.0000 80 chr1:184943603-184943683 1.0000 80 chr19:7553868-7553948 1.0000 80 chr19:16683282-16683362 1.0000 80 chr19:55943764-55943844 1.0000 80 chr1:6320128-6320208 1.0000 80 chr2:219860975-219861055 1.0000 80 chr9:33001579-33001659 1.0000 80 chr6:32163643-32163723 1.0000 80 chr6:27440209-27440289 1.0000 80 chr19:35225426-35225506 1.0000 80 chr4:8442462-8442542 1.0000 80 chr6:150255536-150255616 1.0000 80 chr4:170533736-170533816 1.0000 80 chr9:140353832-140353912 1.0000 80 chr4:153457328-153457408 1.0000 80 chr8:125486883-125486963 1.0000 80 chr11:95523548-95523628 1.0000 80 chr16:48644170-48644250 1.0000 80 chr14:76127492-76127572 1.0000 80 chr1:32110229-32110309 1.0000 80 chr8:21967198-21967278 1.0000 80 chr12:90103440-90103520 1.0000 80 chr19:50354337-50354417 1.0000 80 chr21:40720541-40720621 1.0000 80 chr12:10766162-10766242 1.0000 80 chr10:64802165-64802245 1.0000 80 chrX:48980204-48980284 1.0000 80 chr13:45563624-45563704 1.0000 80 chr19:10982008-10982088 1.0000 80 chr12:27396990-27397070 1.0000 80 chr6:41863042-41863122 1.0000 80 chr12:132845412-13284549 1.0000 80 chr15:40861466-40861546 1.0000 80 chr11:94488766-94488846 1.0000 80 chr11:67374339-67374419 1.0000 80 chr9:26892750-26892830 1.0000 80 chr6:13429767-13429847 1.0000 80 chr14:106267666-10626774 1.0000 80 chr17:40706749-40706829 1.0000 80 chr14:23388114-23388194 1.0000 80 chr17:6916669-6916749 1.0000 80 chr20:18268796-18268876 1.0000 80 chr17:38083845-38083925 1.0000 80 chr13:64650142-64650222 1.0000 80 chr12:125398641-12539872 1.0000 80 chr1:228401330-228401410 1.0000 80 chrX:16737604-16737684 1.0000 80 chr1:151431935-151432015 1.0000 80 chr19:10342199-10342279 1.0000 80 chr17:42856602-42856682 1.0000 80 chrX:135579356-135579436 1.0000 80 chr7:99998381-99998461 1.0000 80 chr5:151304273-151304353 1.0000 80 chr12:108956284-10895636 1.0000 80 chr6:150326707-150326787 1.0000 80 chr19:59084912-59084992 1.0000 80 chr2:242577014-242577094 1.0000 80 chr19:12807429-12807509 1.0000 80 chrX:7895437-7895517 1.0000 80 chr15:65426165-65426245 1.0000 80 chr6:126661208-126661288 1.0000 80 chr16:25118431-25118511 1.0000 80 chr17:7155796-7155876 1.0000 80 chr11:69259259-69259339 1.0000 80 chr19:58521112-58521192 1.0000 80 chr3:185304044-185304124 1.0000 80 chr22:29877025-29877105 1.0000 80 chr22:28315272-28315352 1.0000 80 chr20:44420535-44420615 1.0000 80 chr19:40950640-40950720 1.0000 80 chr22:18893654-18893734 1.0000 80 chr1:86046654-86046734 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_ATF1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/ATF1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.168 C 0.33 G 0.33 T 0.173 Background letter frequencies (from file dataset with add-one prior applied): A 0.168 C 0.33 G 0.33 T 0.173 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TGACGTCA MEME-1 width = 8 sites = 209 llr = 1574 E-value = 2.0e-219 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 Description -------------------------------------------------------------------------------- Simplified A 1:8:::18 pos.-specific C :1:a:18: probability G :81:a:11 matrix T 91:::9:1 bits 2.6 2.3 2.1 1.8 * Relative 1.5 * ** * * Entropy 1.3 * **** * (10.9 bits) 1.0 * **** * 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TGACGTCA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr20:44420535-44420615 43 1.00e-05 CGCGCTCCAG TGACGTCA CGGCGCCACT chrX:7895437-7895517 57 1.00e-05 CGCAGGTATG TGACGTCA TCGCGCCGAC chr12:108956284-10895636 18 1.00e-05 AAAGCTTCGG TGACGTCA GAGAGGCGCG chr19:10342199-10342279 51 1.00e-05 CGCAGCCTGG TGACGTCA CAGTACTCCT chrX:16737604-16737684 39 1.00e-05 TTGTCACAAC TGACGTCA CCAGGGGCGG chr12:125398641-12539872 41 1.00e-05 ACAGAACGGG TGACGTCA CGACACGACG chr14:23388114-23388194 14 1.00e-05 TTTCTGCCCG TGACGTCA GGGGGGAGGC chr6:13429767-13429847 10 1.00e-05 AGGAACTGC TGACGTCA TAAAGCTTGG chr12:27396990-27397070 59 1.00e-05 GTGGTGCGTA TGACGTCA GGGCGAGTCG chr10:64802165-64802245 37 1.00e-05 tatctctgaa tgacgtca tggctctgcg chr12:10766162-10766242 28 1.00e-05 CGCCTTGCAG TGACGTCA TCGCGCGGAA chr21:40720541-40720621 51 1.00e-05 CCCGGCCGCG TGACGTCA CGGCTTCCCG chr8:21967198-21967278 12 1.00e-05 GCTCCGACGG TGACGTCA TCTTTCCTGC chr16:48644170-48644250 38 1.00e-05 CGACGGAAGT TGACGTCA CCCTCAGTCG chr11:95523548-95523628 19 1.00e-05 CGCTACCTTG TGACGTCA CCAGGGAAGA chr9:140353832-140353912 26 1.00e-05 CCACCTACCG TGACGTCA GGGCCCCGGA chr4:170533736-170533816 41 1.00e-05 CGCTGGCGTG TGACGTCA GCGCGTGGAA chr4:8442462-8442542 12 1.00e-05 CCCGCCTCCA TGACGTCA ACGCGCCGCG chr9:33001579-33001659 54 1.00e-05 CGCTGCGGGA TGACGTCA GAGGCCGGCT chr1:6320128-6320208 38 1.00e-05 GGCCGGGGCG TGACGTCA CAGCTCCGGG chr19:55943764-55943844 20 1.00e-05 GTCCCTCTGA TGACGTCA TAGGGCAAGG chr19:7553868-7553948 39 1.00e-05 GGCAACTCCG TGACGTCA CCGCGACGTc chr14:105219421-10521950 51 1.00e-05 CGCGCAGCTG TGACGTCA CGGCGTCGTT chr9:99382149-99382229 41 1.00e-05 CAATGCGGCG TGACGTCA CGGAGACGGG chr14:104095424-10409550 51 1.00e-05 cgaggggcga tgacgtca tgccggcgcg chr21:43430421-43430501 42 1.00e-05 ATCTTGAATT TGACGTCA TCCCACACCA chr19:9649284-9649364 51 1.00e-05 GGCGCACCGC TGACGTCA TTTACGCTCT chr17:1953733-1953813 39 1.00e-05 ACGCGGCCCC TGACGTCA GAGGGCCGTG chr19:17728353-17728433 60 1.00e-05 GCCCCATCCA TGACGTCA CAGGGGAGTG chr1:230760013-230760093 41 1.00e-05 acgcacgatg tgacgtca cacctgattg chr1:153395105-153395185 42 1.00e-05 gaattcactg tgacgtca ctcctgTCTC chr19:36103592-36103672 38 1.00e-05 GGCGCGCCCG TGACGTCA GAGGCGGGCG chrX:102024032-102024112 22 1.00e-05 CATAGTAACC TGACGTCA TATTAGCGAC chr19:50862210-50862290 22 1.00e-05 AACCGTCATA TGACGTCA CTATGGCGTC chr19:51373827-51373907 15 1.00e-05 GCCGGCGCCA TGACGTCA TGTAGCTGCG chrX:102809840-102809920 68 1.00e-05 GTCGCCAAAA TGACGTCA GGTTA chr12:64616330-64616410 36 1.00e-05 TCAGCGCTGG TGACGTCA TGCAAACGTG chr8:42195945-42196025 19 1.00e-05 CCAGGACGCG TGACGTCA CAACAAGCGC chr13:101327228-10132730 37 1.00e-05 GACGCGCCGG TGACGTCA GGCCAGGGGG chr2:74781531-74781611 29 1.00e-05 GCTTTCACTC TGACGTCA CCTTGGGCAT chr8:37605543-37605623 34 1.00e-05 CGCGCCGAAA TGACGTCA CGAGCGCGCC chr19:46135958-46136038 29 1.00e-05 GCCCTCATTG TGACGTCA CAGAGGCGGG chr12:131249962-13125004 45 1.00e-05 atggtgttga tgacgtca tgatgttaat chr19:1042336-1042416 41 1.00e-05 GCGGAGCTGC TGACGTCA CTGCTGCGCA chr14:32030564-32030644 17 1.00e-05 CGTTGCTCCG TGACGTCA TCACTCCGCG chrX:133941136-133941216 24 1.00e-05 GCGCCTGAAG TGACGTCA TTGCCTGCAT chr2:240964754-240964834 46 1.00e-05 CGCGCTGCCG TGACGTCA CGGCCGGGGT chr19:50979505-50979585 26 1.00e-05 ACGCGCACTG TGACGTCA TGATGCGGAG chr9:99179703-99179783 54 1.00e-05 CGCGCGGCAG TGACGTCA GCATCCTGTC chr10:124740124-12474020 39 1.00e-05 TCGCGTATGA TGACGTCA TGCCCGACGC chr7:30174271-30174351 14 1.00e-05 GCTCGCGCTG TGACGTCA CCGGGCTCGC chr7:45808638-45808718 17 1.00e-05 GCGCCTTCCG TGACGTCA CAAGGGCGCG chr14:55738807-55738887 42 1.00e-05 CGTGTGTCTG TGACGTCA GAAGATGGGT chr2:19548159-19548239 50 1.00e-05 GAGGCCTCTG TGACGTCA CGGTGTCTGC chr1:224180314-224180394 32 1.00e-05 CCCGCCCTTG TGACGTCA CGGAAGGCGC chr17:4046928-4047008 38 1.00e-05 CGCGCGCCGA TGACGTCA CGCTCGGCGT chr5:95297720-95297800 64 1.00e-05 TAATCATGTC TGACGTCA CGTCTGGTC chr13:49821995-49822075 5 1.00e-05 TCTA TGACGTCA CACGAGGAGC chr2:28114116-28114196 55 1.00e-05 TTCCGTTCCA TGACGTCA GCAGGGCACA chr11:77185396-77185476 51 1.00e-05 GCTTGCTGCG TGACGTCA TCGCGTCGCG chr4:119512822-119512902 43 1.00e-05 GCGCCCTCCG TGACGTCA CAAGGGCGCG chr6:139456093-139456173 21 1.00e-05 GCGCGGGGCG TGACGTCA CGCGGGCGGT chr18:77439738-77439818 44 1.00e-05 CGCCCTTGCG TGACGTCA CGCGCCCTCC chr2:96068405-96068485 30 1.00e-05 CCATTGCCTG TGACGTCA CAGGATCGCG chr22:39097024-39097104 49 1.00e-05 GACGTAAGTC TGACGTCA TCGGCACCGG chr17:27071370-27071450 33 1.00e-05 GGGCGCCCCG TGACGTCA CGGGGAGGGA chr14:88851951-88852031 30 1.00e-05 CCCTGCGCCG TGACGTCA CAATAGCGAC chr16:67694742-67694822 63 1.00e-05 GCTGCCCCCT TGACGTCA CGCTCCGGAT chr22:26879779-26879859 63 1.00e-05 CGCACGCCGC TGACGTCA GAGACCAATG chr6:15248951-15249031 24 1.00e-05 GTTGTCATTG TGACGTCA CAAAGGGACG chr16:86588797-86588877 44 1.00e-05 TGGCGCGTAG TGACGTCA CCCGCTCCGC chr19:58521112-58521192 38 1.51e-05 GCCCAGCCGA TGACGTAA CCCGCGCTTG chr9:37465408-37465488 36 1.51e-05 TAAGCGGAAG TGACGTAA TGCAAGAGCG chr20:3801390-3801470 12 1.51e-05 ACGGAGGCAG TGACGTAA GCTGTCTTGA chr14:36789851-36789931 32 1.51e-05 CGCTTGGCGA TGACGTAA GACACGGAGT chr17:8152575-8152655 23 1.51e-05 CGCACGCGGA TGACGTAA CAAACGCGCG chr2:143688668-143688748 51 1.51e-05 cgcacgccgc tgacgtaa gtagccttgc chr10:17428846-17428926 54 1.51e-05 cgcacgctga tgacgtaa gccgccttgc chr13:45563624-45563704 45 2.04e-05 ACCACAGGCT TTACGTCA TTTCTCGGCG chr9:32573124-32573204 55 2.04e-05 CGCGCGGTTA TTACGTCA CATCCTGGTT chr3:184053650-184053730 60 2.04e-05 GCCCCCGCGC TTACGTCA CCGGCCCGGT chr18:76829199-76829279 66 2.04e-05 CCGCCGCTCG TTACGTCA TCGGACC chr10:102027391-10202747 47 3.01e-05 CGCAACAATC AGACGTCA GCGCCCTCCA chr3:52444006-52444086 34 3.01e-05 CGCCGGCGGC AGACGTCA CCAAGGCGCG chr13:64650142-64650222 38 4.98e-05 ctcacactga tggcgtca cggcagtggc chr6:27440209-27440289 19 4.98e-05 AGACACAGGA TGGCGTCA GCAGCATACG chr3:53164430-53164510 50 4.98e-05 CGCGATAAGA TGGCGTCA CGGCGCGCCT chr9:102584029-102584109 44 4.98e-05 TAGCGTCCCA TGGCGTCA CATTGACGTC chr1:156698616-156698696 10 4.98e-05 ACGCTTTTG TGGCGTCA CTGCACTGTT chr17:49198364-49198444 7 4.98e-05 AAGCCA TGGCGTCA ACACCCGGCG chr16:67927106-67927186 25 4.98e-05 AGGCTTGTTT TGGCGTCA GCTGCGCGCT chr12:58138358-58138438 41 4.98e-05 AACAAAACAA TGGCGTCA TCGTGAGGTC chr11:69259259-69259339 22 5.98e-05 ttgttGGTGG TGACGTGA GCAGTGACAT chr1:32110229-32110309 37 5.98e-05 CGGTCCTTCA TGACGTGA GCAGGGCGCG chr12:15501607-15501687 27 5.98e-05 cgcaggagaa tgacgtga accccggggg chr5:1746732-1746812 52 5.98e-05 tgacgtgacg tgacgtga cgtggcatgg chr6:126661208-126661288 27 6.49e-05 TGCTCAGGGT TAACGTCA CTACTGAGCG chr12:42719907-42719987 33 6.49e-05 AGCGCTTCGC TAACGTCA TTGCGCGCGC chr22:29877025-29877105 26 1.05e-04 AAGTGCGACG TGACGTCG GCGCTGCGCG chr15:65426165-65426245 26 1.05e-04 CCGACGGAAG TGACGTCG TTACGACGCG chr11:67374339-67374419 35 1.05e-04 GTCGGGCGCG TGACGTCT TTCCTGCGCG chr8:92082231-92082311 44 1.05e-04 TCTGCGCGCC TCACGTCA GGGCCAAGAG chrX:149106786-149106866 34 1.05e-04 agccacgcag tgacgtcg ccacgcacgt chrX:347676-347756 11 1.05e-04 GCGCCCGCGT TCACGTCA CTGCGTCGCG chr6:167880211-167880291 19 1.05e-04 CATGAGATCG TGACGTCG AGACACTGCG chr19:17462840-17462920 43 1.05e-04 TATCTCTTCG TGACGTCT ACATGGCCAC chr1:7831308-7831388 23 1.05e-04 ctccgcctag tgacgtct ttgccccgcg chr5:1345260-1345340 32 1.10e-04 GGCGCGTGTG TGACGTTA CCCGCCCGCG chrX:19361980-19362060 37 1.10e-04 GCGCAGCGCA TGACGTTA TTACGACTCT chr17:7155796-7155876 27 1.32e-04 CACTGGGTCA TGACGCCA TCAGAGGGCG chrX:135579356-135579436 6 1.32e-04 CTTTT TGACGCCA TAGTGGGCGT chr16:71879813-71879893 59 1.32e-04 GGGACGAGCT TGACGCCA TCTCCGGGCG chr7:56019533-56019613 30 1.32e-04 GCGTACGGCG TGACGCCA TCCCGCTGCG chr8:42195584-42195664 25 1.32e-04 TTTGACAGTG TGACGCCA GTGTCGCCTC chr2:110962574-110962654 36 1.32e-04 CGCCAGAAGG TGACGCCA TCGATGTGCG chr14:76127492-76127572 36 1.52e-04 TGCGCGGCGG TGACGACA TTCGCCCGCG chr8:125486883-125486963 12 1.52e-04 CCATGGGTGA TGACGACA TGGGGAGCGT chr19:35225426-35225506 64 1.52e-04 CTTTGGGTTA TGTCGTCA TGAAGCCGG chr7:102036788-102036868 15 1.52e-04 CGCGCGGCTG TGTCGTCA TACTTGCGCG chr2:68290122-68290202 14 1.52e-04 CGGGCAACGA TGACGACA ATGACGCGCC chr6:34664699-34664779 14 1.52e-04 CGCCTCTTAG TGTCGTCA CAAACTCGTG chr17:79093580-79093660 10 1.52e-04 CGCCTCCCA TGACGACA CGGGCCAAAG chr19:29704079-29704159 29 1.52e-04 GCGGGACGCG TGACGACA GCGCGCCGCC chr6:150255536-150255616 33 1.57e-04 GAGACAATTG TGACATCA TGGTGGATGA chr1:154600433-154600513 33 1.57e-04 CGCAGATTGG TGACATCA TTGGCGCGCC chr14:61447791-61447871 6 1.57e-04 TTCTA TGACATCA TCACTGTTCG chr1:4052251-4052331 38 1.81e-04 gtcatagggg tgatgtca aaggggagat chr12:131249285-13124936 24 1.81e-04 acagtgttga tgatgtca tggtgctgat chr11:16626065-16626145 30 1.81e-04 CCCGGGACGC GGACGTCA TCCGAGCGCC chr15:40861466-40861546 22 2.16e-04 TGGGGCCGAG TGACGTCC TCAGATCGCG chr12:90103440-90103520 39 2.16e-04 TGAGAGGCTC TGACGTCC GTGTTTCCAT chr4:1714783-1714863 17 2.16e-04 TGCCCGTCCA TGACGTCC TCCACTGTGT chr11:506841-506921 35 2.16e-04 TGCACCGCGA TGACGTCC TCAAGGCGCG chr22:50683422-50683502 59 2.21e-04 CGCGCCGGAA ATACGTCA CGGGAACGCC chr15:29561995-29562075 58 2.34e-04 AGCCTGCGCC TTGCGTCA GGGCGGCTGG chr2:30670058-30670138 3 2.34e-04 CG TTGCGTCA CGGCGCCTGC chr12:39932515-39932595 25 2.34e-04 gcaaggctac ttgcgtca acagggtgcg chr19:40950640-40950720 32 2.60e-04 GCGCGGGGGA TGACGTAG CGGAAGACCA chr9:134955265-134955345 30 2.60e-04 CGCTCGCTGA TGACGTAT CTCCGAAGAC chr14:99947697-99947777 35 2.60e-04 CGCAGCGTGA TGACGTAG GTCCCCGACA chr14:24769007-24769087 23 2.60e-04 CGCGGAACTA TGACGTAG TAGCTGCGTC chr9:6015603-6015683 65 2.60e-04 CTCGAAGCAG TGACGTAG GCGAGGCG chr22:18893654-18893734 44 2.85e-04 TCCTTCTGAA TGACGCAA GGGGCGGGGC chr17:4607408-4607488 32 2.85e-04 CGTGGCGCGA TGACGCAA ACACACCGCG chr10:113943489-11394356 42 2.85e-04 CGCACCCTGA TGACGCAA CCGGCGCGTG chr19:15560781-15560861 24 3.40e-04 cgcgccgccg TGACCTCA GCGCGACAGC chr8:145743311-145743391 20 3.89e-04 AGCCAATGGG AGGCGTCA ACGTCATcgc chr9:139377510-139377590 25 3.89e-04 CGTGTCCGGC TTACGACA TCAGCGCGcg chr18:77748569-77748649 58 3.89e-04 CCGTGCGTGC TGACGGCA TGTGCGTATA chr22:32058199-32058279 52 3.89e-04 CGCACGCTTA AGGCGTCA CGAGTCTCGA chr3:160282833-160282913 25 3.89e-04 GCGCTAGCAG AGGCGTCA CAGACGGGCC chr1:2343987-2344067 23 3.89e-04 CGAGAACTGA TGACGGCA CGACGTGGCT chr20:18268796-18268876 37 4.38e-04 ATGCGCCCCG AAACGTCA TTTCCGCGCG chr2:237994474-237994554 51 4.38e-04 CGGCGGCTTT AAACGTCA TCGCGGGCGC chr18:21013472-21013552 48 4.87e-04 GGATGGAGGA ACACGTCA TCAGCCAGGG chr22:28315272-28315352 52 5.98e-04 CCGCGACCAG TCGCGTCA GCGCGCGAGG chr3:185304044-185304124 32 5.98e-04 GGCTCTTGAA TCGCGTCA CAAATCAGCG chr16:25118431-25118511 28 5.98e-04 CCTCGCTCTC TCGCGTCA CTTCCGGCGC chr17:38083845-38083925 30 5.98e-04 GCCGGTCCCC GTACGTCA CCGCCCCGCG chr9:26892750-26892830 50 5.98e-04 CGGCAGGCAC TGGCGTCG CAGGTTATGC chr19:16683282-16683362 11 5.98e-04 CGCTGCCTCC TCGCGTCA TCCCTCCGCG chr5:72861526-72861606 40 5.98e-04 GCGTGCTCTG GTACGTCA TCTTCGCGCG chr18:5296892-5296972 70 5.98e-04 TGCCTGTGTC TGGCGTCG GGA chr2:190305778-190305858 25 5.98e-04 CGCGAGAGGC TCGCGTCA TCCTGCAGCG chrX:152736366-152736446 18 5.98e-04 CAGGCCTTGC TGGCGTCG CCCCTGCTGC chr1:228401330-228401410 37 6.70e-04 TACATCTGCG AGACGCCA GAGGGCAGCC chr7:23145292-23145372 29 6.70e-04 CGCGCCACTG TGACGTGT CAGGCCCCGC chr13:45915351-45915431 54 6.70e-04 ACGCAGGCGG TGACGTGG CACGAAGAGC chrX:11129849-11129929 29 6.70e-04 CTCCTGGCTG TGACGTGG TTTCTCAGCG chr17:17380259-17380339 35 6.70e-04 CGCGCGGTGG TGACGTGT AGAGTGCGCG chr1:86046654-86046734 46 7.58e-04 CGCTCGCCTT AGTCGTCA CCCTTCTCCA chr19:1885483-1885563 35 8.34e-04 GCCCCGGAAG TGACGCGA GGAGCGCGCG chr8:17104332-17104412 58 8.34e-04 CGCTAGATGA TGACGCGA CACGCAGAGG chr19:12807429-12807509 41 8.94e-04 CGCTGTCTGA TGACGTTT ATGCGCCCAC chr4:123073408-123073488 55 8.94e-04 CGCTGGCGTG TGACGTTG CTGCCTGACG chr17:6916669-6916749 53 9.94e-04 CCCGTGATGA TGACGCCT CCAGAGAGGA chr5:6713298-6713378 38 9.94e-04 GCGTAGCTTC TGACGCCG TCCTCACCCC chr13:103249182-10324926 33 9.94e-04 CGCCGTTGGC TTACGTAG CAGCACGTGA chr1:243418392-243418472 60 1.10e-03 tcgccgctgt tgtcgtcg CTGCCGCTGC chr7:5553407-5553487 21 1.10e-03 AGGAGCGGGC TCTCGTCA CTTCCGGCGC chr5:43121577-43121657 50 1.10e-03 CGGTGTGCGT CGACGTAA GTGACGCGCA chr17:56709450-56709530 23 1.10e-03 CGCGTAACGC TGACGACT ATAAAGCGCG chr13:45492495-45492575 2 1.19e-03 G GGGCGTCA TAACACCGCG chr17:40706749-40706829 45 1.29e-03 GCGGCTCCAA CTACGTCA CCGCCATGCA chr4:148605328-148605408 58 1.37e-03 CACGCTACGC GAACGTCA GCGCGCCCGA chr12:132845412-13284549 29 1.52e-03 ccggaaaggc tgacgtgc agccgacgta chr14:50235317-50235397 47 1.52e-03 GGGCCGCGAC GGACGTCG CTCGGCTGTG chr3:51533991-51534071 39 1.52e-03 CCCACATATT ATGCGTCA CTCGCGCGCT chr9:139760857-139760937 27 1.52e-03 CTCGTCTGAG GGACGTCG TGGCCGGGCG chr2:202507410-202507490 25 1.52e-03 CGCAGGCGCA ATGCGTCA TCGGGCCGCG chr11:63706251-63706331 25 1.52e-03 GGCTCTGGCC GCACGTCA TTCCCGGCGC chr14:71067346-71067426 50 1.52e-03 GGCGCAAAGT AAACGTAA GCCTAGGCCG chr5:176297160-176297240 26 1.52e-03 TGTCATTAGC ATGCGTCA TCAAGGCCAG chr2:219860975-219861055 70 1.69e-03 TCCCTGACGC GGACGCCA AGT chr19:59084912-59084992 42 1.78e-03 CGCGGCGCGA TGACGTTC CTCTGTGATC chr6:52463157-52463237 28 1.78e-03 CCTGATTAGG GGTCGTCA TCAGTCCGCG chr19:7627866-7627946 56 1.90e-03 GAGGTGCTAC TGACGCCC CCTCTGTGTC chr9:129568208-129568288 35 2.16e-03 GACCGCAGTT TGGCCTCA ACTCTGACAG chr12:498741-498821 21 2.16e-03 aggcgCGACG CGACGTGA CGCTTTCTTC chr22:29866517-29866597 34 2.29e-03 GGGATGGCTG TGACGCAG GCGTGCCCGC chr17:42856602-42856682 43 2.48e-03 GTGATGCCGG CCACGTCA TCCCTCCCGC chr19:54975953-54976033 56 2.48e-03 GCACAGTATT TGACGAAT GGGACTGCGG chr1:70671284-70671364 16 2.48e-03 GCCCCGCTCC TTTCGTGA GCGCGCGCTC chr1:236030340-236030420 45 2.48e-03 CCGGCGTCGC AGGCGTGA CGCGTGGAAC chr10:116697928-11669800 33 2.48e-03 CGCACTCTTG TTGCATCA TCAGCGTGCA chr1:184943603-184943683 24 2.93e-03 AGGAGGCAAG AGGCGTCG CCTTCTGGGG chr10:104159404-10415948 44 2.93e-03 CGCCACCTGC TGACGGCG CAGGACGAGA chr3:123442586-123442666 63 3.39e-03 CCGTCTTGAG TGATGTAT AAACTaggag chr19:55987892-55987972 68 4.42e-03 ACGTGCGTTG TGACGCAC CGACG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr20:44420535-44420615 1e-05 42_[+1]_30 chrX:7895437-7895517 1e-05 56_[+1]_16 chr12:108956284-10895636 1e-05 17_[+1]_55 chr19:10342199-10342279 1e-05 50_[+1]_22 chrX:16737604-16737684 1e-05 38_[+1]_34 chr12:125398641-12539872 1e-05 40_[+1]_32 chr14:23388114-23388194 1e-05 13_[+1]_59 chr6:13429767-13429847 1e-05 9_[+1]_63 chr12:27396990-27397070 1e-05 58_[+1]_14 chr10:64802165-64802245 1e-05 36_[+1]_36 chr12:10766162-10766242 1e-05 27_[+1]_45 chr21:40720541-40720621 1e-05 50_[+1]_22 chr8:21967198-21967278 1e-05 11_[+1]_61 chr16:48644170-48644250 1e-05 37_[+1]_35 chr11:95523548-95523628 1e-05 18_[+1]_54 chr9:140353832-140353912 1e-05 25_[+1]_47 chr4:170533736-170533816 1e-05 40_[+1]_32 chr4:8442462-8442542 1e-05 11_[+1]_61 chr9:33001579-33001659 1e-05 53_[+1]_19 chr1:6320128-6320208 1e-05 37_[+1]_35 chr19:55943764-55943844 1e-05 19_[+1]_53 chr19:7553868-7553948 1e-05 38_[+1]_34 chr14:105219421-10521950 1e-05 50_[+1]_22 chr9:99382149-99382229 1e-05 40_[+1]_32 chr14:104095424-10409550 1e-05 50_[+1]_22 chr21:43430421-43430501 1e-05 41_[+1]_31 chr19:9649284-9649364 1e-05 50_[+1]_22 chr17:1953733-1953813 1e-05 38_[+1]_34 chr19:17728353-17728433 1e-05 59_[+1]_13 chr1:230760013-230760093 1e-05 40_[+1]_32 chr1:153395105-153395185 1e-05 41_[+1]_31 chr19:36103592-36103672 1e-05 37_[+1]_35 chrX:102024032-102024112 1e-05 21_[+1]_51 chr19:50862210-50862290 1e-05 21_[+1]_51 chr19:51373827-51373907 1e-05 14_[+1]_58 chrX:102809840-102809920 1e-05 67_[+1]_5 chr12:64616330-64616410 1e-05 35_[+1]_37 chr8:42195945-42196025 1e-05 18_[+1]_54 chr13:101327228-10132730 1e-05 36_[+1]_36 chr2:74781531-74781611 1e-05 28_[+1]_44 chr8:37605543-37605623 1e-05 33_[+1]_39 chr19:46135958-46136038 1e-05 28_[+1]_44 chr12:131249962-13125004 1e-05 44_[+1]_28 chr19:1042336-1042416 1e-05 40_[+1]_32 chr14:32030564-32030644 1e-05 16_[+1]_56 chrX:133941136-133941216 1e-05 23_[+1]_49 chr2:240964754-240964834 1e-05 45_[+1]_27 chr19:50979505-50979585 1e-05 25_[+1]_47 chr9:99179703-99179783 1e-05 53_[+1]_19 chr10:124740124-12474020 1e-05 38_[+1]_34 chr7:30174271-30174351 1e-05 13_[+1]_59 chr7:45808638-45808718 1e-05 16_[+1]_56 chr14:55738807-55738887 1e-05 41_[+1]_31 chr2:19548159-19548239 1e-05 49_[+1]_23 chr1:224180314-224180394 1e-05 31_[+1]_41 chr17:4046928-4047008 1e-05 37_[+1]_35 chr5:95297720-95297800 1e-05 63_[+1]_9 chr13:49821995-49822075 1e-05 4_[+1]_68 chr2:28114116-28114196 1e-05 54_[+1]_18 chr11:77185396-77185476 1e-05 50_[+1]_22 chr4:119512822-119512902 1e-05 42_[+1]_30 chr6:139456093-139456173 1e-05 20_[+1]_52 chr18:77439738-77439818 1e-05 43_[+1]_29 chr2:96068405-96068485 1e-05 29_[+1]_43 chr22:39097024-39097104 1e-05 48_[+1]_24 chr17:27071370-27071450 1e-05 32_[+1]_40 chr14:88851951-88852031 1e-05 29_[+1]_43 chr16:67694742-67694822 1e-05 62_[+1]_10 chr22:26879779-26879859 1e-05 62_[+1]_10 chr6:15248951-15249031 1e-05 23_[+1]_49 chr16:86588797-86588877 1e-05 43_[+1]_29 chr19:58521112-58521192 1.5e-05 37_[+1]_35 chr9:37465408-37465488 1.5e-05 35_[+1]_37 chr20:3801390-3801470 1.5e-05 11_[+1]_61 chr14:36789851-36789931 1.5e-05 31_[+1]_41 chr17:8152575-8152655 1.5e-05 22_[+1]_50 chr2:143688668-143688748 1.5e-05 50_[+1]_22 chr10:17428846-17428926 1.5e-05 53_[+1]_19 chr13:45563624-45563704 2e-05 44_[+1]_28 chr9:32573124-32573204 2e-05 54_[+1]_18 chr3:184053650-184053730 2e-05 59_[+1]_13 chr18:76829199-76829279 2e-05 65_[+1]_7 chr10:102027391-10202747 3e-05 46_[+1]_26 chr3:52444006-52444086 3e-05 33_[+1]_39 chr13:64650142-64650222 5e-05 37_[+1]_35 chr6:27440209-27440289 5e-05 18_[+1]_54 chr3:53164430-53164510 5e-05 49_[+1]_23 chr9:102584029-102584109 5e-05 43_[+1]_29 chr1:156698616-156698696 5e-05 9_[+1]_63 chr17:49198364-49198444 5e-05 6_[+1]_66 chr16:67927106-67927186 5e-05 24_[+1]_48 chr12:58138358-58138438 5e-05 40_[+1]_32 chr11:69259259-69259339 6e-05 21_[+1]_51 chr1:32110229-32110309 6e-05 36_[+1]_36 chr12:15501607-15501687 6e-05 26_[+1]_46 chr5:1746732-1746812 6e-05 51_[+1]_21 chr6:126661208-126661288 6.5e-05 26_[+1]_46 chr12:42719907-42719987 6.5e-05 32_[+1]_40 chr22:29877025-29877105 0.0001 25_[+1]_47 chr15:65426165-65426245 0.0001 25_[+1]_47 chr11:67374339-67374419 0.0001 34_[+1]_38 chr8:92082231-92082311 0.0001 43_[+1]_29 chrX:149106786-149106866 0.0001 33_[+1]_39 chrX:347676-347756 0.0001 10_[+1]_62 chr6:167880211-167880291 0.0001 18_[+1]_54 chr19:17462840-17462920 0.0001 42_[+1]_30 chr1:7831308-7831388 0.0001 22_[+1]_50 chr5:1345260-1345340 0.00011 31_[+1]_41 chrX:19361980-19362060 0.00011 36_[+1]_36 chr17:7155796-7155876 0.00013 26_[+1]_46 chrX:135579356-135579436 0.00013 5_[+1]_67 chr16:71879813-71879893 0.00013 58_[+1]_14 chr7:56019533-56019613 0.00013 29_[+1]_43 chr8:42195584-42195664 0.00013 24_[+1]_48 chr2:110962574-110962654 0.00013 35_[+1]_37 chr14:76127492-76127572 0.00015 35_[+1]_37 chr8:125486883-125486963 0.00015 11_[+1]_61 chr19:35225426-35225506 0.00015 63_[+1]_9 chr7:102036788-102036868 0.00015 14_[+1]_58 chr2:68290122-68290202 0.00015 13_[+1]_59 chr6:34664699-34664779 0.00015 13_[+1]_59 chr17:79093580-79093660 0.00015 9_[+1]_63 chr19:29704079-29704159 0.00015 28_[+1]_44 chr6:150255536-150255616 0.00016 32_[+1]_40 chr1:154600433-154600513 0.00016 32_[+1]_40 chr14:61447791-61447871 0.00016 5_[+1]_67 chr1:4052251-4052331 0.00018 37_[+1]_35 chr12:131249285-13124936 0.00018 23_[+1]_49 chr11:16626065-16626145 0.00018 29_[+1]_43 chr15:40861466-40861546 0.00022 21_[+1]_51 chr12:90103440-90103520 0.00022 38_[+1]_34 chr4:1714783-1714863 0.00022 16_[+1]_56 chr11:506841-506921 0.00022 34_[+1]_38 chr22:50683422-50683502 0.00022 58_[+1]_14 chr15:29561995-29562075 0.00023 57_[+1]_15 chr2:30670058-30670138 0.00023 2_[+1]_70 chr12:39932515-39932595 0.00023 24_[+1]_48 chr19:40950640-40950720 0.00026 31_[+1]_41 chr9:134955265-134955345 0.00026 29_[+1]_43 chr14:99947697-99947777 0.00026 34_[+1]_38 chr14:24769007-24769087 0.00026 22_[+1]_50 chr9:6015603-6015683 0.00026 64_[+1]_8 chr22:18893654-18893734 0.00029 43_[+1]_29 chr17:4607408-4607488 0.00029 31_[+1]_41 chr10:113943489-11394356 0.00029 41_[+1]_31 chr19:15560781-15560861 0.00034 23_[+1]_49 chr8:145743311-145743391 0.00039 19_[+1]_53 chr9:139377510-139377590 0.00039 24_[+1]_48 chr18:77748569-77748649 0.00039 57_[+1]_15 chr22:32058199-32058279 0.00039 51_[+1]_21 chr3:160282833-160282913 0.00039 24_[+1]_48 chr1:2343987-2344067 0.00039 22_[+1]_50 chr20:18268796-18268876 0.00044 36_[+1]_36 chr2:237994474-237994554 0.00044 50_[+1]_22 chr18:21013472-21013552 0.00049 47_[+1]_25 chr22:28315272-28315352 0.0006 51_[+1]_21 chr3:185304044-185304124 0.0006 31_[+1]_41 chr16:25118431-25118511 0.0006 27_[+1]_45 chr17:38083845-38083925 0.0006 29_[+1]_43 chr9:26892750-26892830 0.0006 49_[+1]_23 chr19:16683282-16683362 0.0006 10_[+1]_62 chr5:72861526-72861606 0.0006 39_[+1]_33 chr18:5296892-5296972 0.0006 69_[+1]_3 chr2:190305778-190305858 0.0006 24_[+1]_48 chrX:152736366-152736446 0.0006 17_[+1]_55 chr1:228401330-228401410 0.00067 36_[+1]_36 chr7:23145292-23145372 0.00067 28_[+1]_44 chr13:45915351-45915431 0.00067 53_[+1]_19 chrX:11129849-11129929 0.00067 28_[+1]_44 chr17:17380259-17380339 0.00067 34_[+1]_38 chr1:86046654-86046734 0.00076 45_[+1]_27 chr19:1885483-1885563 0.00083 34_[+1]_38 chr8:17104332-17104412 0.00083 57_[+1]_15 chr19:12807429-12807509 0.00089 40_[+1]_32 chr4:123073408-123073488 0.00089 54_[+1]_18 chr17:6916669-6916749 0.00099 52_[+1]_20 chr5:6713298-6713378 0.00099 37_[+1]_35 chr13:103249182-10324926 0.00099 32_[+1]_40 chr1:243418392-243418472 0.0011 59_[+1]_13 chr7:5553407-5553487 0.0011 20_[+1]_52 chr5:43121577-43121657 0.0011 49_[+1]_23 chr17:56709450-56709530 0.0011 22_[+1]_50 chr13:45492495-45492575 0.0012 1_[+1]_71 chr17:40706749-40706829 0.0013 44_[+1]_28 chr4:148605328-148605408 0.0014 57_[+1]_15 chr12:132845412-13284549 0.0015 28_[+1]_44 chr14:50235317-50235397 0.0015 46_[+1]_26 chr3:51533991-51534071 0.0015 38_[+1]_34 chr9:139760857-139760937 0.0015 26_[+1]_46 chr2:202507410-202507490 0.0015 24_[+1]_48 chr11:63706251-63706331 0.0015 24_[+1]_48 chr14:71067346-71067426 0.0015 49_[+1]_23 chr5:176297160-176297240 0.0015 25_[+1]_47 chr2:219860975-219861055 0.0017 69_[+1]_3 chr19:59084912-59084992 0.0018 41_[+1]_31 chr6:52463157-52463237 0.0018 27_[+1]_45 chr19:7627866-7627946 0.0019 55_[+1]_17 chr9:129568208-129568288 0.0022 34_[+1]_38 chr12:498741-498821 0.0022 20_[+1]_52 chr22:29866517-29866597 0.0023 33_[+1]_39 chr17:42856602-42856682 0.0025 42_[+1]_30 chr19:54975953-54976033 0.0025 55_[+1]_17 chr1:70671284-70671364 0.0025 15_[+1]_57 chr1:236030340-236030420 0.0025 44_[+1]_28 chr10:116697928-11669800 0.0025 32_[+1]_40 chr1:184943603-184943683 0.0029 23_[+1]_49 chr10:104159404-10415948 0.0029 43_[+1]_29 chr3:123442586-123442666 0.0034 62_[+1]_10 chr19:55987892-55987972 0.0044 67_[+1]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGACGTCA width=8 seqs=209 chr20:44420535-44420615 ( 43) TGACGTCA 1 chrX:7895437-7895517 ( 57) TGACGTCA 1 chr12:108956284-10895636 ( 18) TGACGTCA 1 chr19:10342199-10342279 ( 51) TGACGTCA 1 chrX:16737604-16737684 ( 39) TGACGTCA 1 chr12:125398641-12539872 ( 41) TGACGTCA 1 chr14:23388114-23388194 ( 14) TGACGTCA 1 chr6:13429767-13429847 ( 10) TGACGTCA 1 chr12:27396990-27397070 ( 59) TGACGTCA 1 chr10:64802165-64802245 ( 37) TGACGTCA 1 chr12:10766162-10766242 ( 28) TGACGTCA 1 chr21:40720541-40720621 ( 51) TGACGTCA 1 chr8:21967198-21967278 ( 12) TGACGTCA 1 chr16:48644170-48644250 ( 38) TGACGTCA 1 chr11:95523548-95523628 ( 19) TGACGTCA 1 chr9:140353832-140353912 ( 26) TGACGTCA 1 chr4:170533736-170533816 ( 41) TGACGTCA 1 chr4:8442462-8442542 ( 12) TGACGTCA 1 chr9:33001579-33001659 ( 54) TGACGTCA 1 chr1:6320128-6320208 ( 38) TGACGTCA 1 chr19:55943764-55943844 ( 20) TGACGTCA 1 chr19:7553868-7553948 ( 39) TGACGTCA 1 chr14:105219421-10521950 ( 51) TGACGTCA 1 chr9:99382149-99382229 ( 41) TGACGTCA 1 chr14:104095424-10409550 ( 51) TGACGTCA 1 chr21:43430421-43430501 ( 42) TGACGTCA 1 chr19:9649284-9649364 ( 51) TGACGTCA 1 chr17:1953733-1953813 ( 39) TGACGTCA 1 chr19:17728353-17728433 ( 60) TGACGTCA 1 chr1:230760013-230760093 ( 41) TGACGTCA 1 chr1:153395105-153395185 ( 42) TGACGTCA 1 chr19:36103592-36103672 ( 38) TGACGTCA 1 chrX:102024032-102024112 ( 22) TGACGTCA 1 chr19:50862210-50862290 ( 22) TGACGTCA 1 chr19:51373827-51373907 ( 15) TGACGTCA 1 chrX:102809840-102809920 ( 68) TGACGTCA 1 chr12:64616330-64616410 ( 36) TGACGTCA 1 chr8:42195945-42196025 ( 19) TGACGTCA 1 chr13:101327228-10132730 ( 37) TGACGTCA 1 chr2:74781531-74781611 ( 29) TGACGTCA 1 chr8:37605543-37605623 ( 34) TGACGTCA 1 chr19:46135958-46136038 ( 29) TGACGTCA 1 chr12:131249962-13125004 ( 45) TGACGTCA 1 chr19:1042336-1042416 ( 41) TGACGTCA 1 chr14:32030564-32030644 ( 17) TGACGTCA 1 chrX:133941136-133941216 ( 24) TGACGTCA 1 chr2:240964754-240964834 ( 46) TGACGTCA 1 chr19:50979505-50979585 ( 26) TGACGTCA 1 chr9:99179703-99179783 ( 54) TGACGTCA 1 chr10:124740124-12474020 ( 39) TGACGTCA 1 chr7:30174271-30174351 ( 14) TGACGTCA 1 chr7:45808638-45808718 ( 17) TGACGTCA 1 chr14:55738807-55738887 ( 42) TGACGTCA 1 chr2:19548159-19548239 ( 50) TGACGTCA 1 chr1:224180314-224180394 ( 32) TGACGTCA 1 chr17:4046928-4047008 ( 38) TGACGTCA 1 chr5:95297720-95297800 ( 64) TGACGTCA 1 chr13:49821995-49822075 ( 5) TGACGTCA 1 chr2:28114116-28114196 ( 55) TGACGTCA 1 chr11:77185396-77185476 ( 51) TGACGTCA 1 chr4:119512822-119512902 ( 43) TGACGTCA 1 chr6:139456093-139456173 ( 21) TGACGTCA 1 chr18:77439738-77439818 ( 44) TGACGTCA 1 chr2:96068405-96068485 ( 30) TGACGTCA 1 chr22:39097024-39097104 ( 49) TGACGTCA 1 chr17:27071370-27071450 ( 33) TGACGTCA 1 chr14:88851951-88852031 ( 30) TGACGTCA 1 chr16:67694742-67694822 ( 63) TGACGTCA 1 chr22:26879779-26879859 ( 63) TGACGTCA 1 chr6:15248951-15249031 ( 24) TGACGTCA 1 chr16:86588797-86588877 ( 44) TGACGTCA 1 chr19:58521112-58521192 ( 38) TGACGTAA 1 chr9:37465408-37465488 ( 36) TGACGTAA 1 chr20:3801390-3801470 ( 12) TGACGTAA 1 chr14:36789851-36789931 ( 32) TGACGTAA 1 chr17:8152575-8152655 ( 23) TGACGTAA 1 chr2:143688668-143688748 ( 51) TGACGTAA 1 chr10:17428846-17428926 ( 54) TGACGTAA 1 chr13:45563624-45563704 ( 45) TTACGTCA 1 chr9:32573124-32573204 ( 55) TTACGTCA 1 chr3:184053650-184053730 ( 60) TTACGTCA 1 chr18:76829199-76829279 ( 66) TTACGTCA 1 chr10:102027391-10202747 ( 47) AGACGTCA 1 chr3:52444006-52444086 ( 34) AGACGTCA 1 chr13:64650142-64650222 ( 38) TGGCGTCA 1 chr6:27440209-27440289 ( 19) TGGCGTCA 1 chr3:53164430-53164510 ( 50) TGGCGTCA 1 chr9:102584029-102584109 ( 44) TGGCGTCA 1 chr1:156698616-156698696 ( 10) TGGCGTCA 1 chr17:49198364-49198444 ( 7) TGGCGTCA 1 chr16:67927106-67927186 ( 25) TGGCGTCA 1 chr12:58138358-58138438 ( 41) TGGCGTCA 1 chr11:69259259-69259339 ( 22) TGACGTGA 1 chr1:32110229-32110309 ( 37) TGACGTGA 1 chr12:15501607-15501687 ( 27) TGACGTGA 1 chr5:1746732-1746812 ( 52) TGACGTGA 1 chr6:126661208-126661288 ( 27) TAACGTCA 1 chr12:42719907-42719987 ( 33) TAACGTCA 1 chr22:29877025-29877105 ( 26) TGACGTCG 1 chr15:65426165-65426245 ( 26) TGACGTCG 1 chr11:67374339-67374419 ( 35) TGACGTCT 1 chr8:92082231-92082311 ( 44) TCACGTCA 1 chrX:149106786-149106866 ( 34) TGACGTCG 1 chrX:347676-347756 ( 11) TCACGTCA 1 chr6:167880211-167880291 ( 19) TGACGTCG 1 chr19:17462840-17462920 ( 43) TGACGTCT 1 chr1:7831308-7831388 ( 23) TGACGTCT 1 chr5:1345260-1345340 ( 32) TGACGTTA 1 chrX:19361980-19362060 ( 37) TGACGTTA 1 chr17:7155796-7155876 ( 27) TGACGCCA 1 chrX:135579356-135579436 ( 6) TGACGCCA 1 chr16:71879813-71879893 ( 59) TGACGCCA 1 chr7:56019533-56019613 ( 30) TGACGCCA 1 chr8:42195584-42195664 ( 25) TGACGCCA 1 chr2:110962574-110962654 ( 36) TGACGCCA 1 chr14:76127492-76127572 ( 36) TGACGACA 1 chr8:125486883-125486963 ( 12) TGACGACA 1 chr19:35225426-35225506 ( 64) TGTCGTCA 1 chr7:102036788-102036868 ( 15) TGTCGTCA 1 chr2:68290122-68290202 ( 14) TGACGACA 1 chr6:34664699-34664779 ( 14) TGTCGTCA 1 chr17:79093580-79093660 ( 10) TGACGACA 1 chr19:29704079-29704159 ( 29) TGACGACA 1 chr6:150255536-150255616 ( 33) TGACATCA 1 chr1:154600433-154600513 ( 33) TGACATCA 1 chr14:61447791-61447871 ( 6) TGACATCA 1 chr1:4052251-4052331 ( 38) TGATGTCA 1 chr12:131249285-13124936 ( 24) TGATGTCA 1 chr11:16626065-16626145 ( 30) GGACGTCA 1 chr15:40861466-40861546 ( 22) TGACGTCC 1 chr12:90103440-90103520 ( 39) TGACGTCC 1 chr4:1714783-1714863 ( 17) TGACGTCC 1 chr11:506841-506921 ( 35) TGACGTCC 1 chr22:50683422-50683502 ( 59) ATACGTCA 1 chr15:29561995-29562075 ( 58) TTGCGTCA 1 chr2:30670058-30670138 ( 3) TTGCGTCA 1 chr12:39932515-39932595 ( 25) TTGCGTCA 1 chr19:40950640-40950720 ( 32) TGACGTAG 1 chr9:134955265-134955345 ( 30) TGACGTAT 1 chr14:99947697-99947777 ( 35) TGACGTAG 1 chr14:24769007-24769087 ( 23) TGACGTAG 1 chr9:6015603-6015683 ( 65) TGACGTAG 1 chr22:18893654-18893734 ( 44) TGACGCAA 1 chr17:4607408-4607488 ( 32) TGACGCAA 1 chr10:113943489-11394356 ( 42) TGACGCAA 1 chr19:15560781-15560861 ( 24) TGACCTCA 1 chr8:145743311-145743391 ( 20) AGGCGTCA 1 chr9:139377510-139377590 ( 25) TTACGACA 1 chr18:77748569-77748649 ( 58) TGACGGCA 1 chr22:32058199-32058279 ( 52) AGGCGTCA 1 chr3:160282833-160282913 ( 25) AGGCGTCA 1 chr1:2343987-2344067 ( 23) TGACGGCA 1 chr20:18268796-18268876 ( 37) AAACGTCA 1 chr2:237994474-237994554 ( 51) AAACGTCA 1 chr18:21013472-21013552 ( 48) ACACGTCA 1 chr22:28315272-28315352 ( 52) TCGCGTCA 1 chr3:185304044-185304124 ( 32) TCGCGTCA 1 chr16:25118431-25118511 ( 28) TCGCGTCA 1 chr17:38083845-38083925 ( 30) GTACGTCA 1 chr9:26892750-26892830 ( 50) TGGCGTCG 1 chr19:16683282-16683362 ( 11) TCGCGTCA 1 chr5:72861526-72861606 ( 40) GTACGTCA 1 chr18:5296892-5296972 ( 70) TGGCGTCG 1 chr2:190305778-190305858 ( 25) TCGCGTCA 1 chrX:152736366-152736446 ( 18) TGGCGTCG 1 chr1:228401330-228401410 ( 37) AGACGCCA 1 chr7:23145292-23145372 ( 29) TGACGTGT 1 chr13:45915351-45915431 ( 54) TGACGTGG 1 chrX:11129849-11129929 ( 29) TGACGTGG 1 chr17:17380259-17380339 ( 35) TGACGTGT 1 chr1:86046654-86046734 ( 46) AGTCGTCA 1 chr19:1885483-1885563 ( 35) TGACGCGA 1 chr8:17104332-17104412 ( 58) TGACGCGA 1 chr19:12807429-12807509 ( 41) TGACGTTT 1 chr4:123073408-123073488 ( 55) TGACGTTG 1 chr17:6916669-6916749 ( 53) TGACGCCT 1 chr5:6713298-6713378 ( 38) TGACGCCG 1 chr13:103249182-10324926 ( 33) TTACGTAG 1 chr1:243418392-243418472 ( 60) TGTCGTCG 1 chr7:5553407-5553487 ( 21) TCTCGTCA 1 chr5:43121577-43121657 ( 50) CGACGTAA 1 chr17:56709450-56709530 ( 23) TGACGACT 1 chr13:45492495-45492575 ( 2) GGGCGTCA 1 chr17:40706749-40706829 ( 45) CTACGTCA 1 chr4:148605328-148605408 ( 58) GAACGTCA 1 chr12:132845412-13284549 ( 29) TGACGTGC 1 chr14:50235317-50235397 ( 47) GGACGTCG 1 chr3:51533991-51534071 ( 39) ATGCGTCA 1 chr9:139760857-139760937 ( 27) GGACGTCG 1 chr2:202507410-202507490 ( 25) ATGCGTCA 1 chr11:63706251-63706331 ( 25) GCACGTCA 1 chr14:71067346-71067426 ( 50) AAACGTAA 1 chr5:176297160-176297240 ( 26) ATGCGTCA 1 chr2:219860975-219861055 ( 70) GGACGCCA 1 chr19:59084912-59084992 ( 42) TGACGTTC 1 chr6:52463157-52463237 ( 28) GGTCGTCA 1 chr19:7627866-7627946 ( 56) TGACGCCC 1 chr9:129568208-129568288 ( 35) TGGCCTCA 1 chr12:498741-498821 ( 21) CGACGTGA 1 chr22:29866517-29866597 ( 34) TGACGCAG 1 chr17:42856602-42856682 ( 43) CCACGTCA 1 chr19:54975953-54976033 ( 56) TGACGAAT 1 chr1:70671284-70671364 ( 16) TTTCGTGA 1 chr1:236030340-236030420 ( 45) AGGCGTGA 1 chr10:116697928-11669800 ( 33) TTGCATCA 1 chr1:184943603-184943683 ( 24) AGGCGTCG 1 chr10:104159404-10415948 ( 44) TGACGGCG 1 chr3:123442586-123442666 ( 63) TGATGTAT 1 chr19:55987892-55987972 ( 68) TGACGCAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 6.97224 E= 2.0e-219 -104 -411 -278 230 -254 -265 134 -100 229 -1435 -120 -217 -1435 158 -1435 -359 -313 -511 156 -1435 -213 -194 -452 232 -67 128 -230 -285 226 -311 -165 -171 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 209 E= 2.0e-219 0.081340 0.019139 0.047847 0.851675 0.028708 0.052632 0.832536 0.086124 0.818182 0.000000 0.143541 0.038278 0.000000 0.985646 0.000000 0.014354 0.019139 0.009569 0.971292 0.000000 0.038278 0.086124 0.014354 0.861244 0.105263 0.803828 0.066986 0.023923 0.803828 0.038278 0.105263 0.052632 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-1 regular expression -------------------------------------------------------------------------------- TGACGTCA -------------------------------------------------------------------------------- Time 4.81 secs. ******************************************************************************** ******************************************************************************** MOTIF TGACGTCA MEME-2 width = 8 sites = 33 llr = 289 E-value = 1.2e-006 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::a:1:18 pos.-specific C :::7119: probability G :a:18::1 matrix T a::2:9:1 bits 2.6 * * 2.3 * * 2.1 * * 1.8 * * * Relative 1.5 *** * * Entropy 1.3 *** * * (12.6 bits) 1.0 *** **** 0.8 *** **** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel TGACGTCA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:1953733-1953813 55 1.00e-05 CAGAGGGCCG TGACGTCA AAGATGTCCC chr19:36103592-36103672 15 1.00e-05 CGGCAACCGA TGACGTCA CTGTTGGCGC chr12:64616330-64616410 52 1.00e-05 CATGCAAACG TGACGTCA GCCCTGGCCA chr2:74781531-74781611 48 1.00e-05 CTTGGGCATA TGACGTCA CGCGCAGCCA chr19:50979505-50979585 53 1.00e-05 GCGGGCTTTA TGACGTCA CACAAGAGCG chr4:119512822-119512902 18 1.00e-05 GAGGCTTCCG TGACGTCA CAAGGGTGCG chr17:27071370-27071450 51 1.00e-05 CGGGGAGGGA TGACGTCA AGCCCCGAGG chr6:15248951-15249031 73 1.00e-05 TCCTCCTCCG TGACGTCA chr1:4052251-4052331 24 1.53e-05 catggggagg tgatgtca taggggtgat chr12:131249285-13124936 38 1.53e-05 gtcatggtgc tgatgtca tggtgttggt chr17:79093580-79093660 66 1.53e-05 GCTCCTCCCA TGATGTCA CACATTA chr6:150255536-150255616 59 2.04e-05 GAGACAATTG TGACATCA TGGTGGATGA chr14:23388114-23388194 57 4.58e-05 CACGCATTGG TGACGTCT GGTGGGGACC chr21:43430421-43430501 64 4.58e-05 ACACCAGGGA TGAGGTCA TCGCAGGCA chr9:102584029-102584109 55 4.58e-05 GGCGTCACAT TGACGTCT CGCATTCCAG chr19:50862210-50862290 63 4.58e-05 CCTACCTGGA TGACGTAA TCATGGGCCG chr12:58138358-58138438 52 4.58e-05 GGCGTCATCG TGAGGTCA CTGCAGAACA chr5:95297720-95297800 30 4.58e-05 GGTAAGAGGC TGACGTCT AGGTGACGCG chr6:139456093-139456173 50 4.58e-05 CCGTCAGCCG TGAGGTCA CCTGGTGGGC chr22:39097024-39097104 38 4.58e-05 GCGTCACGCC TGACGTAA GTCTGACGTC chr12:131249962-13125004 70 4.85e-05 aatgCAGTGT TGATATCA TGG chr14:55738807-55738887 10 5.36e-05 AGTCCACGA TGAAGTCA TAGGGCTGTG chr6:34664699-34664779 43 6.36e-05 CGTCCCCGCG TGACCTCA CCGCTGCGGG chr3:184053650-184053730 3 1.10e-04 TG TGACGTCG CTGCGCCCCG chr16:67927106-67927186 47 1.10e-04 CGCGCTGTGA TGACGCCA CGACGCTAAC chr1:224180314-224180394 57 1.10e-04 CGCGCTCTTG TGACGTCG CAGGGAACTA chr19:17462840-17462920 62 1.10e-04 CATGGCCACG TGACGCCA TCACCACGGT chr2:28114116-28114196 11 1.10e-04 GTGCGCTGTA TGACGTCG ACGTGACGCA chr11:77185396-77185476 15 1.10e-04 CATCGGCGCG TGACGCCA GAGGCTGGGG chr12:27396990-27397070 24 1.25e-04 AGACGGGCGT TGACGACA GAAGGCTACT chr2:68290122-68290202 65 1.25e-04 CGCTTCCCGA TGATCTCA CGCTGCTC chr5:1746732-1746812 42 1.35e-04 gaacgtaacg tgacgtga cgtgacgtga chr2:143688668-143688748 27 2.06e-04 ttcctgcttc tgatatct tgctggcgca -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:1953733-1953813 1e-05 54_[+2]_18 chr19:36103592-36103672 1e-05 14_[+2]_58 chr12:64616330-64616410 1e-05 51_[+2]_21 chr2:74781531-74781611 1e-05 47_[+2]_25 chr19:50979505-50979585 1e-05 52_[+2]_20 chr4:119512822-119512902 1e-05 17_[+2]_55 chr17:27071370-27071450 1e-05 50_[+2]_22 chr6:15248951-15249031 1e-05 72_[+2] chr1:4052251-4052331 1.5e-05 23_[+2]_49 chr12:131249285-13124936 1.5e-05 37_[+2]_35 chr17:79093580-79093660 1.5e-05 65_[+2]_7 chr6:150255536-150255616 2e-05 58_[+2]_14 chr14:23388114-23388194 4.6e-05 56_[+2]_16 chr21:43430421-43430501 4.6e-05 63_[+2]_9 chr9:102584029-102584109 4.6e-05 54_[+2]_18 chr19:50862210-50862290 4.6e-05 62_[+2]_10 chr12:58138358-58138438 4.6e-05 51_[+2]_21 chr5:95297720-95297800 4.6e-05 29_[+2]_43 chr6:139456093-139456173 4.6e-05 49_[+2]_23 chr22:39097024-39097104 4.6e-05 37_[+2]_35 chr12:131249962-13125004 4.8e-05 69_[+2]_3 chr14:55738807-55738887 5.4e-05 9_[+2]_63 chr6:34664699-34664779 6.4e-05 42_[+2]_30 chr3:184053650-184053730 0.00011 2_[+2]_70 chr16:67927106-67927186 0.00011 46_[+2]_26 chr1:224180314-224180394 0.00011 56_[+2]_16 chr19:17462840-17462920 0.00011 61_[+2]_11 chr2:28114116-28114196 0.00011 10_[+2]_62 chr11:77185396-77185476 0.00011 14_[+2]_58 chr12:27396990-27397070 0.00013 23_[+2]_49 chr2:68290122-68290202 0.00013 64_[+2]_8 chr5:1746732-1746812 0.00014 41_[+2]_31 chr2:143688668-143688748 0.00021 26_[+2]_46 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGACGTCA width=8 seqs=33 chr17:1953733-1953813 ( 55) TGACGTCA 1 chr19:36103592-36103672 ( 15) TGACGTCA 1 chr12:64616330-64616410 ( 52) TGACGTCA 1 chr2:74781531-74781611 ( 48) TGACGTCA 1 chr19:50979505-50979585 ( 53) TGACGTCA 1 chr4:119512822-119512902 ( 18) TGACGTCA 1 chr17:27071370-27071450 ( 51) TGACGTCA 1 chr6:15248951-15249031 ( 73) TGACGTCA 1 chr1:4052251-4052331 ( 24) TGATGTCA 1 chr12:131249285-13124936 ( 38) TGATGTCA 1 chr17:79093580-79093660 ( 66) TGATGTCA 1 chr6:150255536-150255616 ( 59) TGACATCA 1 chr14:23388114-23388194 ( 57) TGACGTCT 1 chr21:43430421-43430501 ( 64) TGAGGTCA 1 chr9:102584029-102584109 ( 55) TGACGTCT 1 chr19:50862210-50862290 ( 63) TGACGTAA 1 chr12:58138358-58138438 ( 52) TGAGGTCA 1 chr5:95297720-95297800 ( 30) TGACGTCT 1 chr6:139456093-139456173 ( 50) TGAGGTCA 1 chr22:39097024-39097104 ( 38) TGACGTAA 1 chr12:131249962-13125004 ( 70) TGATATCA 1 chr14:55738807-55738887 ( 10) TGAAGTCA 1 chr6:34664699-34664779 ( 43) TGACCTCA 1 chr3:184053650-184053730 ( 3) TGACGTCG 1 chr16:67927106-67927186 ( 47) TGACGCCA 1 chr1:224180314-224180394 ( 57) TGACGTCG 1 chr19:17462840-17462920 ( 62) TGACGCCA 1 chr2:28114116-28114196 ( 11) TGACGTCG 1 chr11:77185396-77185476 ( 15) TGACGCCA 1 chr12:27396990-27397070 ( 24) TGACGACA 1 chr2:68290122-68290202 ( 65) TGATCTCA 1 chr5:1746732-1746812 ( 42) TGACGTGA 1 chr2:143688668-143688748 ( 27) TGATATCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.4541 E= 1.2e-006 -1169 -1169 -1169 253 -1169 -1169 160 -1169 258 -1169 -1169 -1169 -247 108 -186 7 -88 -244 136 -1169 -247 -186 -1169 235 -147 146 -344 -1169 223 -1169 -186 -51 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 33 E= 1.2e-006 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.030303 0.696970 0.090909 0.181818 0.090909 0.060606 0.848485 0.000000 0.030303 0.090909 0.000000 0.878788 0.060606 0.909091 0.030303 0.000000 0.787879 0.000000 0.090909 0.121212 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACGTCA MEME-2 regular expression -------------------------------------------------------------------------------- TGACGTCA -------------------------------------------------------------------------------- Time 8.26 secs. ******************************************************************************** ******************************************************************************** MOTIF AAAAGGAA MEME-3 width = 8 sites = 2 llr = 26 E-value = 1.1e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAAAGGAA MEME-3 Description -------------------------------------------------------------------------------- Simplified A aaaa::aa pos.-specific C :::::::: probability G ::::aa:: matrix T :::::::: bits 2.6 **** ** 2.3 **** ** 2.1 **** ** 1.8 **** ** Relative 1.5 ******** Entropy 1.3 ******** (18.7 bits) 1.0 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel AAAAGGAA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAGGAA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:9649284-9649364 32 2.45e-06 CCGGCGTCAC AAAAGGAA CGGCGCACCG chr14:100150213-10015029 1 2.45e-06 . AAAAGGAA GGGGCCTAAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAGGAA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:9649284-9649364 2.4e-06 31_[+3]_41 chr14:100150213-10015029 2.4e-06 [+3]_72 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAGGAA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAAAGGAA width=8 seqs=2 chr19:9649284-9649364 ( 32) AAAAGGAA 1 chr14:100150213-10015029 ( 1) AAAAGGAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAGGAA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 1.1e+004 257 -765 -765 -765 257 -765 -765 -765 257 -765 -765 -765 257 -765 -765 -765 -765 -765 160 -765 -765 -765 160 -765 257 -765 -765 -765 257 -765 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAGGAA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 1.1e+004 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAAGGAA MEME-3 regular expression -------------------------------------------------------------------------------- AAAAGGAA -------------------------------------------------------------------------------- Time 11.66 secs. ******************************************************************************** ******************************************************************************** MOTIF AAGSAAAW MEME-4 width = 8 sites = 3 llr = 35 E-value = 6.2e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAGSAAAW MEME-4 Description -------------------------------------------------------------------------------- Simplified A aa::aaa7 pos.-specific C :::7:::: probability G ::a3:::: matrix T :::::::3 bits 2.6 ** *** 2.3 ** *** 2.1 ** *** 1.8 ** *** Relative 1.5 *** **** Entropy 1.3 *** **** (16.8 bits) 1.0 *** **** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel AAGCAAAA consensus G T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGSAAAW MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr14:106267666-10626774 3 2.45e-06 GA AAGCAAAA CCACGGACAG chr9:134955265-134955345 6 2.45e-06 TTCGC AAGCAAAA AAGCCGCGCT chr19:29704079-29704159 50 9.94e-06 CGCCGCCGGA AAGGAAAT TCTGCAGTCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGSAAAW MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr14:106267666-10626774 2.4e-06 2_[+4]_70 chr9:134955265-134955345 2.4e-06 5_[+4]_67 chr19:29704079-29704159 9.9e-06 49_[+4]_23 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGSAAAW MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAGSAAAW width=8 seqs=3 chr14:106267666-10626774 ( 3) AAGCAAAA 1 chr9:134955265-134955345 ( 6) AAGCAAAA 1 chr19:29704079-29704159 ( 50) AAGGAAAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGSAAAW MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.0179 E= 6.2e+004 257 -823 -823 -823 257 -823 -823 -823 -823 -823 160 -823 -823 101 2 -823 257 -823 -823 -823 257 -823 -823 -823 257 -823 -823 -823 199 -823 -823 95 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGSAAAW MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 3 E= 6.2e+004 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.666667 0.333333 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.666667 0.000000 0.000000 0.333333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGSAAAW MEME-4 regular expression -------------------------------------------------------------------------------- AAG[CG]AAA[AT] -------------------------------------------------------------------------------- Time 15.07 secs. ******************************************************************************** ******************************************************************************** MOTIF ACAAAACA MEME-5 width = 8 sites = 2 llr = 26 E-value = 1.2e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif ACAAAACA MEME-5 Description -------------------------------------------------------------------------------- Simplified A a:aaaa:a pos.-specific C :a::::a: probability G :::::::: matrix T :::::::: bits 2.6 * **** * 2.3 * **** * 2.1 * **** * 1.8 * **** * Relative 1.5 ******** Entropy 1.3 ******** (18.7 bits) 1.0 ******** 0.8 ******** 0.5 ******** 0.3 ******** 0.0 -------- Multilevel ACAAAACA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAAAACA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrX:16737604-16737684 20 2.45e-06 ATCCACGCGC ACAAAACA GTTGTCACAA chr12:58138358-58138438 32 2.45e-06 TGACGCAATA ACAAAACA ATGGCGTCAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAAAACA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrX:16737604-16737684 2.4e-06 19_[+5]_53 chr12:58138358-58138438 2.4e-06 31_[+5]_41 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAAAACA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ACAAAACA width=8 seqs=2 chrX:16737604-16737684 ( 20) ACAAAACA 1 chr12:58138358-58138438 ( 32) ACAAAACA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAAAACA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 13.1555 E= 1.2e+004 257 -765 -765 -765 -765 159 -765 -765 257 -765 -765 -765 257 -765 -765 -765 257 -765 -765 -765 257 -765 -765 -765 -765 159 -765 -765 257 -765 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAAAACA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 1.2e+004 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACAAAACA MEME-5 regular expression -------------------------------------------------------------------------------- ACAAAACA -------------------------------------------------------------------------------- Time 18.46 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:52444006-52444086 9.04e-02 33_[+1(3.01e-05)]_39 chr17:17380259-17380339 2.23e-01 80 chr5:176297160-176297240 6.61e-01 80 chr5:36151247-36151327 4.77e-02 80 chr18:21013472-21013552 3.55e-02 80 chr16:86588797-86588877 1.28e-03 43_[+1(1.00e-05)]_29 chr5:1746732-1746812 5.69e-03 41_[+1(5.98e-05)]_2_[+1(5.98e-05)]_\ 21 chr6:15248951-15249031 6.67e-05 23_[+1(1.00e-05)]_41_[+1(1.00e-05)] chr22:26879779-26879859 3.03e-04 62_[+1(1.00e-05)]_10 chr1:7831308-7831388 1.99e-02 22_[+2(4.58e-05)]_50 chr16:67694742-67694822 7.29e-05 62_[+1(1.00e-05)]_10 chrX:19361980-19362060 1.56e-01 80 chr9:71394846-71394926 7.45e-01 80 chr14:88851951-88852031 1.31e-04 29_[+1(1.00e-05)]_43 chr17:27071370-27071450 1.12e-03 13_[+2(6.36e-05)]_11_[+1(1.00e-05)]_\ 10_[+1(1.00e-05)]_22 chr19:15560781-15560861 5.15e-02 23_[+2(6.36e-05)]_49 chr22:39097024-39097104 7.43e-04 25_[+1(4.98e-05)]_4_[+1(1.51e-05)]_\ 3_[+1(1.00e-05)]_24 chr2:96068405-96068485 5.26e-04 29_[+1(1.00e-05)]_43 chr22:42353796-42353876 6.57e-01 80 chr18:77439738-77439818 2.90e-04 43_[+1(1.00e-05)]_29 chr9:6015603-6015683 2.77e-02 80 chr6:139456093-139456173 1.29e-03 20_[+1(1.00e-05)]_21_[+2(4.58e-05)]_\ 23 chr18:76829199-76829279 3.32e-03 65_[+1(2.04e-05)]_7 chr4:119512822-119512902 3.41e-04 1_[+1(5.98e-05)]_8_[+1(1.00e-05)]_\ 17_[+1(1.00e-05)]_30 chrX:152736366-152736446 2.66e-01 80 chr10:17428846-17428926 7.61e-04 53_[+1(1.51e-05)]_19 chr11:77185396-77185476 8.69e-04 50_[+1(1.00e-05)]_22 chr14:24769007-24769087 7.58e-02 80 chrX:11129849-11129929 7.23e-02 80 chr16:75589259-75589339 5.43e-02 80 chr2:28114116-28114196 3.80e-04 54_[+1(1.00e-05)]_18 chr9:128845119-128845199 3.08e-01 80 chr3:120461510-120461590 7.91e-01 80 chr13:49821995-49822075 3.80e-04 4_[+1(1.00e-05)]_68 chr4:123073408-123073488 3.97e-01 80 chr2:143688668-143688748 3.10e-03 50_[+1(1.51e-05)]_22 chr3:183146404-183146484 1.00e+00 80 chr19:18747796-18747876 1.00e+00 80 chr20:57463855-57463935 8.79e-01 80 chr19:17462840-17462920 1.94e-02 42_[+2(4.58e-05)]_30 chr13:45915351-45915431 1.83e-01 80 chr5:95297720-95297800 1.70e-04 29_[+2(4.58e-05)]_26_[+1(1.00e-05)]_\ 9 chr12:58138358-58138438 1.85e-07 31_[+5(2.45e-06)]_1_[+1(4.98e-05)]_\ 3_[+2(4.58e-05)]_21 chr13:45492495-45492575 3.19e-01 80 chr3:123442586-123442666 8.98e-04 44_[+5(1.24e-05)]_28 chr17:4046928-4047008 8.40e-04 37_[+1(1.00e-05)]_35 chr2:110962574-110962654 9.65e-04 80 chr1:224180314-224180394 2.80e-04 31_[+1(1.00e-05)]_41 chr12:39932515-39932595 8.72e-02 80 chr10:113943489-11394356 5.81e-02 80 chr17:8152575-8152655 2.85e-04 22_[+1(1.51e-05)]_50 chr14:100150213-10015029 8.15e-03 [+3(2.45e-06)]_72 chr2:19548159-19548239 9.86e-04 49_[+1(1.00e-05)]_23 chr14:55738807-55738887 9.56e-05 9_[+2(5.36e-05)]_24_[+1(1.00e-05)]_\ 31 chr14:99947697-99947777 1.32e-02 80 chr7:45808638-45808718 2.46e-04 16_[+1(1.00e-05)]_56 chr16:67927106-67927186 1.30e-02 24_[+1(4.98e-05)]_48 chr8:42195584-42195664 2.14e-04 51_[+5(8.52e-05)]_21 chr1:85155993-85156073 9.41e-01 80 chr19:29704079-29704159 3.52e-06 49_[+4(9.94e-06)]_23 chr17:79093580-79093660 1.16e-03 65_[+2(1.53e-05)]_7 chr9:102582448-102582528 6.50e-01 80 chr7:30174271-30174351 1.28e-03 13_[+1(1.00e-05)]_59 chr10:124740124-12474020 8.40e-04 38_[+1(1.00e-05)]_34 chr17:49198364-49198444 7.26e-03 6_[+1(4.98e-05)]_66 chr7:23145292-23145372 2.22e-01 80 chr22:50683422-50683502 1.54e-01 80 chr9:99179703-99179783 8.08e-04 53_[+1(1.00e-05)]_19 chr19:50979505-50979585 3.78e-05 25_[+1(1.00e-05)]_19_[+1(1.00e-05)]_\ 20 chr2:240964754-240964834 1.29e-03 45_[+1(1.00e-05)]_27 chr2:190305778-190305858 1.36e-02 80 chrX:133941136-133941216 6.31e-05 23_[+1(1.00e-05)]_49 chr1:2343987-2344067 1.48e-01 80 chr6:160941293-160941373 9.31e-01 80 chr10:116697928-11669800 3.02e-02 80 chr14:36789851-36789931 6.59e-04 31_[+1(1.51e-05)]_41 chr17:56709450-56709530 3.32e-02 80 chr22:29866517-29866597 5.56e-01 80 chr21:44394642-44394722 9.97e-01 80 chr4:148605328-148605408 2.91e-01 80 chr14:71067346-71067426 1.70e-02 80 chr11:16626065-16626145 6.32e-02 80 chr14:32030564-32030644 8.04e-04 16_[+1(1.00e-05)]_56 chr6:167880211-167880291 2.19e-02 80 chr19:1042336-1042416 5.26e-04 40_[+1(1.00e-05)]_32 chr6:34664699-34664779 2.02e-04 42_[+2(6.36e-05)]_30 chr12:131249962-13125004 7.43e-04 44_[+1(1.00e-05)]_17_[+2(4.85e-05)]_\ 3 chr8:17104332-17104412 1.55e-01 80 chr20:3801390-3801470 4.47e-03 11_[+1(1.51e-05)]_61 chr14:61447791-61447871 5.28e-03 5_[+2(2.04e-05)]_67 chr19:46135958-46136038 3.80e-04 28_[+1(1.00e-05)]_44 chr17:4607408-4607488 7.51e-03 80 chr3:48488031-48488111 5.25e-01 80 chr8:37605543-37605623 9.58e-06 33_[+1(1.00e-05)]_39 chr3:160282833-160282913 4.29e-01 80 chr2:74781531-74781611 1.04e-03 8_[+2(1.53e-05)]_12_[+1(1.00e-05)]_\ 11_[+1(1.00e-05)]_25 chr13:101327228-10132730 6.43e-04 36_[+1(1.00e-05)]_36 chr8:42195945-42196025 1.39e-04 18_[+1(1.00e-05)]_54 chr12:64616330-64616410 8.15e-06 35_[+1(1.00e-05)]_8_[+1(1.00e-05)]_\ 21 chr2:237994474-237994554 3.47e-01 80 chrX:102809840-102809920 4.67e-06 67_[+1(1.00e-05)]_5 chr1:156698616-156698696 6.43e-02 9_[+1(4.98e-05)]_63 chr11:63706251-63706331 9.05e-01 80 chr18:5296892-5296972 3.19e-01 80 chr3:184053650-184053730 1.19e-02 59_[+1(2.04e-05)]_13 chr1:236030340-236030420 7.39e-02 80 chr19:51373827-51373907 7.35e-04 14_[+1(1.00e-05)]_58 chr19:50862210-50862290 7.15e-04 21_[+1(1.00e-05)]_3_[+1(4.98e-05)]_\ 22_[+1(1.51e-05)]_10 chr2:68290122-68290202 1.47e-02 80 chr5:43121577-43121657 4.78e-01 80 chr8:142726252-142726332 9.91e-01 80 chr2:202507410-202507490 8.48e-01 80 chr1:19181216-19181296 6.68e-01 80 chrX:347676-347756 1.69e-01 80 chrX:102024032-102024112 3.96e-04 21_[+1(1.00e-05)]_51 chr10:102027391-10202747 8.35e-03 46_[+1(3.01e-05)]_26 chr5:1345260-1345340 1.60e-01 80 chr19:36103592-36103672 7.81e-04 14_[+1(1.00e-05)]_15_[+1(1.00e-05)]_\ 35 chr9:32573124-32573204 1.49e-02 54_[+1(2.04e-05)]_18 chr9:134955265-134955345 4.73e-06 5_[+4(2.45e-06)]_67 chr9:139760857-139760937 5.57e-01 80 chr22:32058199-32058279 5.71e-01 80 chr14:23775929-23776009 9.98e-01 80 chr1:153395105-153395185 1.21e-03 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number of motifs (5) found. ******************************************************************************** CPU: c22n04.farnam.hpc.yale.internal ********************************************************************************