******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/K562/fasta/RankLinear0.6_40/ARID3A.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr8:67521715-67521795 1.0000 80 chr18:8654649-8654729 1.0000 80 chr10:62528766-62528846 1.0000 80 chr2:175209880-175209960 1.0000 80 chr6:135772911-135772991 1.0000 80 chr2:167038247-167038327 1.0000 80 chr1:218503534-218503614 1.0000 80 chr7:130380813-130380893 1.0000 80 chr6:138121224-138121304 1.0000 80 chr1:100194490-100194570 1.0000 80 chr8:54923145-54923225 1.0000 80 chr16:67383241-67383321 1.0000 80 chr4:110899217-110899297 1.0000 80 chr16:70563442-70563522 1.0000 80 chr2:143792028-143792108 1.0000 80 chr1:86965828-86965908 1.0000 80 chr13:92374712-92374792 1.0000 80 chr5:137516033-137516113 1.0000 80 chr12:94184689-94184769 1.0000 80 chr12:122820729-12282080 1.0000 80 chr6:135410568-135410648 1.0000 80 chr7:86782777-86782857 1.0000 80 chr1:229850954-229851034 1.0000 80 chr1:173224483-173224563 1.0000 80 chrX:65330126-65330206 1.0000 80 chr7:123134394-123134474 1.0000 80 chr4:79533712-79533792 1.0000 80 chr4:74123033-74123113 1.0000 80 chr11:33187924-33188004 1.0000 80 chrX:11551430-11551510 1.0000 80 chr7:123177237-123177317 1.0000 80 chr3:167765172-167765252 1.0000 80 chr7:43878654-43878734 1.0000 80 chr6:74362458-74362538 1.0000 80 chr20:43948321-43948401 1.0000 80 chr1:54535900-54535980 1.0000 80 chr7:101151229-101151309 1.0000 80 chr11:82638473-82638553 1.0000 80 chr2:113030388-113030468 1.0000 80 chr15:67196139-67196219 1.0000 80 chr17:44290409-44290489 1.0000 80 chr11:61564820-61564900 1.0000 80 chr6:11496593-11496673 1.0000 80 chr11:82578657-82578737 1.0000 80 chr19:51524428-51524508 1.0000 80 chr7:7143155-7143235 1.0000 80 chr1:44229255-44229335 1.0000 80 chr17:27618312-27618392 1.0000 80 chr16:25850204-25850284 1.0000 80 chr22:30485033-30485113 1.0000 80 chr7:128938255-128938335 1.0000 80 chr1:172398592-172398672 1.0000 80 chr3:194125522-194125602 1.0000 80 chr11:75785605-75785685 1.0000 80 chr6:116832661-116832741 1.0000 80 chr1:114378469-114378549 1.0000 80 chr5:80809985-80810065 1.0000 80 chr20:58524331-58524411 1.0000 80 chr6:593291-593371 1.0000 80 chr19:1601800-1601880 1.0000 80 chr9:116639204-116639284 1.0000 80 chr12:27168768-27168848 1.0000 80 chr10:73886102-73886182 1.0000 80 chr7:116628571-116628651 1.0000 80 chr6:125435570-125435650 1.0000 80 chr5:86696300-86696380 1.0000 80 chr6:127624055-127624135 1.0000 80 chr3:185178679-185178759 1.0000 80 chr6:28400989-28401069 1.0000 80 chr7:128099518-128099598 1.0000 80 chr8:110359245-110359325 1.0000 80 chr16:56030117-56030197 1.0000 80 chr1:246166596-246166676 1.0000 80 chr1:63004959-63005039 1.0000 80 chr7:140175705-140175785 1.0000 80 chr7:128503706-128503786 1.0000 80 chr2:86429234-86429314 1.0000 80 chr6:26176039-26176119 1.0000 80 chr7:50182081-50182161 1.0000 80 chr12:121916876-12191695 1.0000 80 chr10:27512963-27513043 1.0000 80 chr6:131961894-131961974 1.0000 80 chr10:22629229-22629309 1.0000 80 chr1:26929007-26929087 1.0000 80 chr11:78125465-78125545 1.0000 80 chr1:7813039-7813119 1.0000 80 chr8:125966101-125966181 1.0000 80 chr7:123357077-123357157 1.0000 80 chr6:70930811-70930891 1.0000 80 chr6:36986489-36986569 1.0000 80 chr10:74820959-74821039 1.0000 80 chr1:93324584-93324664 1.0000 80 chr1:43475158-43475238 1.0000 80 chr11:32334583-32334663 1.0000 80 chr10:93672738-93672818 1.0000 80 chr7:20351211-20351291 1.0000 80 chr12:104647320-10464740 1.0000 80 chr4:39697455-39697535 1.0000 80 chr10:45504151-45504231 1.0000 80 chr1:46710730-46710810 1.0000 80 chr22:20015636-20015716 1.0000 80 chr4:68612585-68612665 1.0000 80 chr15:42792338-42792418 1.0000 80 chr11:72158136-72158216 1.0000 80 chr4:124017374-124017454 1.0000 80 chr15:51995045-51995125 1.0000 80 chr6:157735906-157735986 1.0000 80 chr5:36870691-36870771 1.0000 80 chr11:74170759-74170839 1.0000 80 chr15:101112778-10111285 1.0000 80 chr4:74528562-74528642 1.0000 80 chr1:24853813-24853893 1.0000 80 chr6:158635334-158635414 1.0000 80 chr6:15107300-15107380 1.0000 80 chr2:159757923-159758003 1.0000 80 chr1:33936229-33936309 1.0000 80 chr9:37594628-37594708 1.0000 80 chr1:28743179-28743259 1.0000 80 chr6:71416366-71416446 1.0000 80 chr6:116589835-116589915 1.0000 80 chr6:91319277-91319357 1.0000 80 chr3:150215900-150215980 1.0000 80 chr12:107173926-10717400 1.0000 80 chr3:44277600-44277680 1.0000 80 chr22:21138672-21138752 1.0000 80 chr2:32705195-32705275 1.0000 80 chr2:65593862-65593942 1.0000 80 chr12:123278358-12327843 1.0000 80 chr12:118795683-11879576 1.0000 80 chr5:95000002-95000082 1.0000 80 chr6:37621851-37621931 1.0000 80 chr7:76012536-76012616 1.0000 80 chr11:46299093-46299173 1.0000 80 chr18:3281610-3281690 1.0000 80 chr2:106257927-106258007 1.0000 80 chr1:241694761-241694841 1.0000 80 chr19:9906925-9907005 1.0000 80 chr5:72792922-72793002 1.0000 80 chr9:90788477-90788557 1.0000 80 chr11:6552641-6552721 1.0000 80 chr17:58716256-58716336 1.0000 80 chr6:4008774-4008854 1.0000 80 chr5:54686479-54686559 1.0000 80 chr4:68389161-68389241 1.0000 80 chr5:137371790-137371870 1.0000 80 chr19:1848787-1848867 1.0000 80 chr1:36765676-36765756 1.0000 80 chr6:109704573-109704653 1.0000 80 chr6:56886029-56886109 1.0000 80 chr2:152664987-152665067 1.0000 80 chr4:147263912-147263992 1.0000 80 chr12:46119631-46119711 1.0000 80 chr4:56602952-56603032 1.0000 80 chr12:46825635-46825715 1.0000 80 chr4:74312212-74312292 1.0000 80 chr4:26721731-26721811 1.0000 80 chr19:54345495-54345575 1.0000 80 chr7:111126781-111126861 1.0000 80 chr22:22067610-22067690 1.0000 80 chr6:134478047-134478127 1.0000 80 chr14:51327361-51327441 1.0000 80 chr11:16301826-16301906 1.0000 80 chr11:22809268-22809348 1.0000 80 chr6:26066313-26066393 1.0000 80 chr4:174139963-174140043 1.0000 80 chr15:50886687-50886767 1.0000 80 chr7:105070305-105070385 1.0000 80 chr10:70982118-70982198 1.0000 80 chr7:104621836-104621916 1.0000 80 chr8:38243650-38243730 1.0000 80 chr14:31449440-31449520 1.0000 80 chr3:37332897-37332977 1.0000 80 chr1:206990374-206990454 1.0000 80 chr15:92080112-92080192 1.0000 80 chr3:71257639-71257719 1.0000 80 chr1:242183272-242183352 1.0000 80 chr6:147106296-147106376 1.0000 80 chr17:25794487-25794567 1.0000 80 chr3:5809096-5809176 1.0000 80 chr2:188364821-188364901 1.0000 80 chr9:100686086-100686166 1.0000 80 chr11:10780687-10780767 1.0000 80 chr6:27720181-27720261 1.0000 80 chr6:150589016-150589096 1.0000 80 chr22:22785980-22786060 1.0000 80 chr2:31085088-31085168 1.0000 80 chr10:70977104-70977184 1.0000 80 chr8:103823820-103823900 1.0000 80 chr6:168247818-168247898 1.0000 80 chr1:29360509-29360589 1.0000 80 chr1:112312330-112312410 1.0000 80 chr7:106716510-106716590 1.0000 80 chr1:151224342-151224422 1.0000 80 chr22:22302167-22302247 1.0000 80 chr7:7144119-7144199 1.0000 80 chr9:32943357-32943437 1.0000 80 chr10:11824962-11825042 1.0000 80 chr6:7048389-7048469 1.0000 80 chr8:121096976-121097056 1.0000 80 chr15:88162622-88162702 1.0000 80 chr4:129141602-129141682 1.0000 80 chr13:44833402-44833482 1.0000 80 chr6:15327618-15327698 1.0000 80 chr1:75938237-75938317 1.0000 80 chr9:94807394-94807474 1.0000 80 chr17:41869151-41869231 1.0000 80 chr2:112676199-112676279 1.0000 80 chr12:120667057-12066713 1.0000 80 chr7:157043462-157043542 1.0000 80 chr8:101950951-101951031 1.0000 80 chr17:38115318-38115398 1.0000 80 chr1:182226608-182226688 1.0000 80 chr1:212236330-212236410 1.0000 80 chr2:113842002-113842082 1.0000 80 chr1:211722017-211722097 1.0000 80 chr5:53685965-53686045 1.0000 80 chr3:160061111-160061191 1.0000 80 chr16:53241808-53241888 1.0000 80 chr6:26311424-26311504 1.0000 80 chr15:66112178-66112258 1.0000 80 chr6:26312026-26312106 1.0000 80 chr5:154325374-154325454 1.0000 80 chr16:20703115-20703195 1.0000 80 chr6:10759737-10759817 1.0000 80 chr16:50248010-50248090 1.0000 80 chr6:153185152-153185232 1.0000 80 chr6:125513580-125513660 1.0000 80 chr6:135323499-135323579 1.0000 80 chr15:65596707-65596787 1.0000 80 chr6:126267540-126267620 1.0000 80 chr15:81391537-81391617 1.0000 80 chr9:108371453-108371533 1.0000 80 chr5:39399788-39399868 1.0000 80 chr19:48948671-48948751 1.0000 80 chr1:243610791-243610871 1.0000 80 chr6:42629458-42629538 1.0000 80 chr19:3719185-3719265 1.0000 80 chr15:39997046-39997126 1.0000 80 chr6:144126068-144126148 1.0000 80 chr3:25645842-25645922 1.0000 80 chr2:179261897-179261977 1.0000 80 chr6:49809283-49809363 1.0000 80 chr1:235764542-235764622 1.0000 80 chr14:50053665-50053745 1.0000 80 chr1:51986168-51986248 1.0000 80 chr1:233500587-233500667 1.0000 80 chr1:246614177-246614257 1.0000 80 chr6:168257891-168257971 1.0000 80 chr22:20863808-20863888 1.0000 80 chr2:68258832-68258912 1.0000 80 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/K562/inference_raw/MEME/RankLinear0.6_40_ARID3A/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/K562/fasta/RankLinear0.6_40/ARID3A.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 20000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 20000 norand= no csites= 1000 Letter frequencies in dataset: A 0.292 C 0.207 G 0.204 T 0.296 Background letter frequencies (from file dataset with add-one prior applied): A 0.292 C 0.207 G 0.204 T 0.296 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF AGRKGGCR MEME-1 width = 8 sites = 106 llr = 827 E-value = 1.8e-067 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGRKGGCR MEME-1 Description -------------------------------------------------------------------------------- Simplified A 8:51::24 pos.-specific C ::::::7: probability G :a55aa:4 matrix T 2::4::11 bits 2.3 * ** 2.1 * ** 1.8 * ** 1.6 * ** Relative 1.4 * ** Entropy 1.1 ** ** (11.3 bits) 0.9 *** *** 0.7 ******* 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AGAGGGCA consensus GT AG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGRKGGCR MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:42629458-42629538 23 4.36e-06 TCTGTCCTCT AGGGGGCG CCCCGTTACT chr9:90788477-90788557 8 4.36e-06 TGTCACA AGGGGGCG GCAGGGGCAT chr10:27512963-27513043 43 4.36e-06 TATTACAGCT AGGGGGCG CAgtgcaatg chr1:86965828-86965908 42 4.36e-06 GTATTCCTGT AGGGGGCG ATATACTAAA chr22:22785980-22786060 32 1.06e-05 TCTGGACACC AGAGGGCG CATGGGGATC chr7:104621836-104621916 17 1.06e-05 ATAATGCACT AGAGGGCG CTAAATACAC chr19:54345495-54345575 25 1.06e-05 AGGCACCAGT AGAGGGCG CTGAGACACA chr4:68612585-68612665 24 1.06e-05 TTCATCCACT AGAGGGCG TCTAATAATT chr12:27168768-27168848 46 1.06e-05 AGCTAGCAGA AGAGGGCG CTCTTTTTTT chr11:82578657-82578737 60 1.06e-05 ACACACCACC AGAGGGCG CCCTTATATA chr12:122820729-12282080 36 1.06e-05 CCTCGCCAAC AGAGGGCG CCTACGGCCC chr1:212236330-212236410 54 1.68e-05 GATTACCACC AGGGGGCA TGTACTCATA chr6:26176039-26176119 54 1.68e-05 TCTATTCCCC AGGGGGCA GACTTTTAAT chr1:54535900-54535980 17 1.68e-05 TATAATCACT AGGGGGCA ATAAGACCAT chr6:138121224-138121304 49 1.68e-05 TGTTTTATCC AGGGGGCA GCAGTGAGCT chr20:58524331-58524411 19 2.31e-05 ATTATCCACA AGGTGGCG ACCAAACCCT chr5:154325374-154325454 68 3.21e-05 ATTGGCCAGG AGAGGGCA CATAG chr2:113842002-113842082 35 3.21e-05 gtgtaactct agagggca ccactcacat chr10:11824962-11825042 22 3.21e-05 ATTCTCCAGC AGAGGGCA ATGGGTATTT chr1:46710730-46710810 23 3.21e-05 CATCTCCAGC AGAGGGCA GAAGCCAAAA chr11:32334583-32334663 14 3.21e-05 AAGAACCACT AGAGGGCA GAGCTTTGTG chr6:131961894-131961974 14 3.21e-05 GGAAGAGGAA AGAGGGCA GCTAGAAGAA chr8:110359245-110359325 39 3.21e-05 ATCAGCCACA AGAGGGCA CTTGAAGCCA chr6:127624055-127624135 26 3.21e-05 TGATGACAGC AGAGGGCA CTGTCATATA chr7:116628571-116628651 55 3.21e-05 TATGATCACT AGAGGGCA CTCTTTAAAA chr1:44229255-44229335 38 3.21e-05 CTGAGCCACA AGAGGGCA GAAGAACCTT chr7:123134394-123134474 43 3.21e-05 ATGAGCCACA AGAGGGCA GCAGCTCCAA chr16:70563442-70563522 52 3.21e-05 TCAGGCCTCT AGAGGGCA GTCATAAATC chr2:179261897-179261977 32 4.11e-05 CGTTTCCACT AGATGGCG CAATATTTTA chr6:71416366-71416446 50 4.11e-05 TTGTACCACC AGATGGCG CTCTCTATTA chr18:3281610-3281690 4 5.02e-05 ACT AGGTGGCA CTATTGTTCT chr5:80809985-80810065 32 5.02e-05 TCCTGCCTAT AGGTGGCA ACACTCATAT chr7:7143155-7143235 34 5.02e-05 TTATACCAAC AGGTGGCA GTATTGCTTT chr20:43948321-43948401 44 5.02e-05 TGAAACCGGC AGGTGGCA CTGTTCTCCA chrX:11551430-11551510 14 5.02e-05 TACTCCCACT AGGTGGCA CTTAAGATCC chr11:33187924-33188004 28 5.02e-05 TGAATCCCCC AGGTGGCA GACAAATACA chr4:79533712-79533792 35 5.02e-05 AATTTCCACA AGGTGGCA TGTCAAGTTC chr1:233500587-233500667 51 6.31e-05 TCTGCCCACA AGATGGCA CTACATTATC chr6:157735906-157735986 55 6.31e-05 GTTAACCATT AGATGGCA CCCTTTTGTA chr1:93324584-93324664 12 6.31e-05 TCAAACCAGG AGATGGCA CTCTTTAGTC chr6:36986489-36986569 52 6.31e-05 attgtccggc agatggca gtcaaatgtc chr1:26929007-26929087 31 6.31e-05 TTTGAACAGC AGATGGCA GGATAATCCC chr6:593291-593371 36 6.31e-05 TATGGCCACG AGATGGCA GTATGGCACC chr1:114378469-114378549 33 6.31e-05 AACTGCCACC AGATGGCA CATGACGATA chr1:172398592-172398672 39 6.31e-05 CACTTCCACA AGATGGCA CTGTGTCCCA chr11:61564820-61564900 22 6.31e-05 AGTGGCCACA AGATGGCA CCATGCTCCA chr6:15327618-15327698 57 7.37e-05 TGAGGCCACG AGGGGGAG ATCTGATGAT chr2:31085088-31085168 9 7.37e-05 AGGACTCC AGGGGGAG CCCATGGCAG chr14:31449440-31449520 9 7.37e-05 actctgtA TGGGGGCG GGGAGAATTA chr5:72792922-72793002 49 7.37e-05 TTCTTCCAAA AGGGGGAG TCTTTCTATA chr11:46299093-46299173 64 7.37e-05 AATATTGATG TGGGGGCG TGGCGCCTT chrX:65330126-65330206 19 7.37e-05 CCTAACCAAT AGGGGGAG TTGCCAGAAT chr1:173224483-173224563 51 7.37e-05 GCTGACCTCT AGGGGGAG CTCAAGGCTC chr6:153185152-153185232 40 8.88e-05 ATTGGCCACT TGAGGGCG CCAAAGCAGA chr17:38115318-38115398 55 8.88e-05 ATTGACCACC AGAGGGAG GTAGAGAGCA chr6:116589835-116589915 5 8.88e-05 ccct agagggag gtatgcatat chr1:33936229-33936309 16 8.88e-05 GAGGCTGTAT TGAGGGCG AGGCGCGCCC chr10:45504151-45504231 13 8.88e-05 TTCAGTCCAG TGAGGGCG CTGCATAAGT chr3:185178679-185178759 22 8.88e-05 CCTCACCACC AGAGGGAG GTACTCCTTT chr10:73886102-73886182 37 8.88e-05 TGTCAACACC AGAGGGAG CTACATTCAT chr7:130380813-130380893 25 8.88e-05 TTATACCCCA AGAGGGAG CCTAGATCCA chr22:20863808-20863888 20 1.10e-04 ATTCCAGAGG AGGGGGAA CGTAGACAAT chr22:22067610-22067690 26 1.10e-04 aacagccacg agggggaa gcaacagtgt chr4:39697455-39697535 39 1.10e-04 TAGGACCACT AGGGGGCT CTGCTAGAAG chr10:70982118-70982198 42 1.16e-04 TGGCTACTTA AGGAGGCG CTGCCTAGGA chr12:121916876-12191695 30 1.16e-04 CTATACCACA AGGAGGCG CTATAAATAA chr19:3719185-3719265 55 1.32e-04 CGCCACCTGC TGGTGGCG GAGTGTCACA chr11:10780687-10780767 16 1.32e-04 agaggtctag aggtggag ccctagagca chr15:51995045-51995125 47 1.32e-04 tgagctcagg aggtggag gctgcaccac chr22:22302167-22302247 5 1.69e-04 CACA AGAGGGCT GTCCTTATCA chr5:137371790-137371870 27 1.69e-04 tccgtaccct agggggtg ccattcacat chr19:1601800-1601880 51 1.69e-04 GCTGGCCAAC AGAGGGCT GAAATTAAAA chr2:86429234-86429314 42 1.78e-04 ttgatccacc agaaggcg cagtagatag chr9:108371453-108371533 21 2.09e-04 TTTGAACACT TGATGGCG CCAAACAGTC chr3:5809096-5809176 53 2.09e-04 gattgccagc agatggag ttggcttata chr15:50886687-50886767 24 2.09e-04 TGATAAGTGG AGGAGGCA GAACTGGTTT chr6:116832661-116832741 12 2.09e-04 TTCCACCAGT AGGAGGCA TTATCTAAAC chr7:101151229-101151309 48 2.09e-04 gaccatgata tgatggcg ccctctaggg chr6:74362458-74362538 13 2.09e-04 CCCGGCTGCC AGATGGAG CTATAAGGTT chr18:8654649-8654729 45 2.09e-04 TTCCACTAGG AGGAGGCA GAGCACGAAT chr19:48948671-48948751 9 2.49e-04 ctgcctcc agagggtg gactttctga chr1:29360509-29360589 16 2.49e-04 tactaaccta aggTGGCT TTTGTGTGTA chr2:188364821-188364901 41 2.49e-04 TGCCAGCAGG TGGTGGCA GTGCACCACA chr5:54686479-54686559 67 2.49e-04 ACCAGGAACT AGGTGGAA TCATTC chr7:140175705-140175785 37 2.49e-04 AACAGCCTGG TGGTGGCA GCATAACACA chr16:67383241-67383321 36 2.62e-04 aatgaccagt agggggcc ttttatgatt chr4:147263912-147263992 26 3.28e-04 ACAGGGCACT AGGTGGTG CTGTGGGACC chr17:44290409-44290489 7 3.28e-04 CAGCTG AGATGGAA TCATTTAAAT chr3:167765172-167765252 53 3.28e-04 ATTATCCACT AGATGGCT CTATAAAATC chr16:50248010-50248090 22 3.47e-04 AAGTACCAGT AGAGGGTA GCAAAAACTG chr2:159757923-159758003 43 3.47e-04 ATCAACCACT AGAGGGTA GTATAGACCA chr6:70930811-70930891 40 3.47e-04 TAAAACCACT AGAGGGTA GTCATGTTAC chr7:50182081-50182161 28 3.47e-04 TTTGGGCACT AGAGGGCC TCCAAGGTTG chr19:1848787-1848867 73 3.86e-04 TTCTGCGGGG AGGTGGCC chr6:15107300-15107380 45 3.86e-04 GAAATCAAGC AGGTGGTA ATCGCTTCTC chr1:218503534-218503614 39 3.86e-04 TGATACCACA AGGTGGTA CTGTTGTACC chr6:158635334-158635414 38 4.62e-04 TTATTCCAGT AGGAGGAG CTCTCAGCAA chr1:246166596-246166676 39 4.71e-04 CAGCGCCATC TGGTGGAG CGGTGGGACT chr6:168257891-168257971 14 5.12e-04 AGAGATAGGA TGGGGGTG GGGATAGTTG chr6:11496593-11496673 60 5.12e-04 CCTCCATGTA TGAGGGCT GTCAACGGAC chr16:53241808-53241888 59 5.33e-04 CTACTTCCGC AGAAGGAG TCAGTATTTT chr6:10759737-10759817 54 6.21e-04 ctcccactag tggtgGCT TTGTGTAATT chr16:20703115-20703195 51 6.21e-04 TGTCTCCCTC TGGTGGAA TGCACATTTT chr15:67196139-67196219 73 6.21e-04 ACTTGCCACC TGGTGGCT chr4:110899217-110899297 49 6.21e-04 GGTATATATG TGGTGGCT TCCCAGCTGC chr5:95000002-95000082 27 7.03e-04 TGTGCACACT AGGAGGTG CTGCTGTGCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGRKGGCR MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:42629458-42629538 4.4e-06 22_[+1]_50 chr9:90788477-90788557 4.4e-06 7_[+1]_65 chr10:27512963-27513043 4.4e-06 42_[+1]_30 chr1:86965828-86965908 4.4e-06 41_[+1]_31 chr22:22785980-22786060 1.1e-05 31_[+1]_41 chr7:104621836-104621916 1.1e-05 16_[+1]_56 chr19:54345495-54345575 1.1e-05 24_[+1]_48 chr4:68612585-68612665 1.1e-05 23_[+1]_49 chr12:27168768-27168848 1.1e-05 45_[+1]_27 chr11:82578657-82578737 1.1e-05 59_[+1]_13 chr12:122820729-12282080 1.1e-05 35_[+1]_37 chr1:212236330-212236410 1.7e-05 53_[+1]_19 chr6:26176039-26176119 1.7e-05 53_[+1]_19 chr1:54535900-54535980 1.7e-05 16_[+1]_56 chr6:138121224-138121304 1.7e-05 48_[+1]_24 chr20:58524331-58524411 2.3e-05 18_[+1]_54 chr5:154325374-154325454 3.2e-05 67_[+1]_5 chr2:113842002-113842082 3.2e-05 34_[+1]_38 chr10:11824962-11825042 3.2e-05 21_[+1]_51 chr1:46710730-46710810 3.2e-05 22_[+1]_50 chr11:32334583-32334663 3.2e-05 13_[+1]_59 chr6:131961894-131961974 3.2e-05 13_[+1]_59 chr8:110359245-110359325 3.2e-05 38_[+1]_34 chr6:127624055-127624135 3.2e-05 25_[+1]_47 chr7:116628571-116628651 3.2e-05 54_[+1]_18 chr1:44229255-44229335 3.2e-05 37_[+1]_35 chr7:123134394-123134474 3.2e-05 42_[+1]_30 chr16:70563442-70563522 3.2e-05 51_[+1]_21 chr2:179261897-179261977 4.1e-05 31_[+1]_41 chr6:71416366-71416446 4.1e-05 49_[+1]_23 chr18:3281610-3281690 5e-05 3_[+1]_69 chr5:80809985-80810065 5e-05 31_[+1]_41 chr7:7143155-7143235 5e-05 33_[+1]_39 chr20:43948321-43948401 5e-05 43_[+1]_29 chrX:11551430-11551510 5e-05 13_[+1]_59 chr11:33187924-33188004 5e-05 27_[+1]_45 chr4:79533712-79533792 5e-05 34_[+1]_38 chr1:233500587-233500667 6.3e-05 50_[+1]_22 chr6:157735906-157735986 6.3e-05 54_[+1]_18 chr1:93324584-93324664 6.3e-05 11_[+1]_61 chr6:36986489-36986569 6.3e-05 51_[+1]_21 chr1:26929007-26929087 6.3e-05 30_[+1]_42 chr6:593291-593371 6.3e-05 35_[+1]_37 chr1:114378469-114378549 6.3e-05 32_[+1]_40 chr1:172398592-172398672 6.3e-05 38_[+1]_34 chr11:61564820-61564900 6.3e-05 21_[+1]_51 chr6:15327618-15327698 7.4e-05 56_[+1]_16 chr2:31085088-31085168 7.4e-05 8_[+1]_64 chr14:31449440-31449520 7.4e-05 8_[+1]_64 chr5:72792922-72793002 7.4e-05 48_[+1]_24 chr11:46299093-46299173 7.4e-05 63_[+1]_9 chrX:65330126-65330206 7.4e-05 18_[+1]_54 chr1:173224483-173224563 7.4e-05 50_[+1]_22 chr6:153185152-153185232 8.9e-05 39_[+1]_33 chr17:38115318-38115398 8.9e-05 54_[+1]_18 chr6:116589835-116589915 8.9e-05 4_[+1]_68 chr1:33936229-33936309 8.9e-05 15_[+1]_57 chr10:45504151-45504231 8.9e-05 12_[+1]_60 chr3:185178679-185178759 8.9e-05 21_[+1]_51 chr10:73886102-73886182 8.9e-05 36_[+1]_36 chr7:130380813-130380893 8.9e-05 24_[+1]_48 chr22:20863808-20863888 0.00011 19_[+1]_53 chr22:22067610-22067690 0.00011 25_[+1]_47 chr4:39697455-39697535 0.00011 38_[+1]_34 chr10:70982118-70982198 0.00012 41_[+1]_31 chr12:121916876-12191695 0.00012 29_[+1]_43 chr19:3719185-3719265 0.00013 54_[+1]_18 chr11:10780687-10780767 0.00013 15_[+1]_57 chr15:51995045-51995125 0.00013 46_[+1]_26 chr22:22302167-22302247 0.00017 4_[+1]_68 chr5:137371790-137371870 0.00017 26_[+1]_46 chr19:1601800-1601880 0.00017 50_[+1]_22 chr2:86429234-86429314 0.00018 41_[+1]_31 chr9:108371453-108371533 0.00021 20_[+1]_52 chr3:5809096-5809176 0.00021 52_[+1]_20 chr15:50886687-50886767 0.00021 23_[+1]_49 chr6:116832661-116832741 0.00021 11_[+1]_61 chr7:101151229-101151309 0.00021 47_[+1]_25 chr6:74362458-74362538 0.00021 12_[+1]_60 chr18:8654649-8654729 0.00021 44_[+1]_28 chr19:48948671-48948751 0.00025 8_[+1]_64 chr1:29360509-29360589 0.00025 15_[+1]_57 chr2:188364821-188364901 0.00025 40_[+1]_32 chr5:54686479-54686559 0.00025 66_[+1]_6 chr7:140175705-140175785 0.00025 36_[+1]_36 chr16:67383241-67383321 0.00026 35_[+1]_37 chr4:147263912-147263992 0.00033 25_[+1]_47 chr17:44290409-44290489 0.00033 6_[+1]_66 chr3:167765172-167765252 0.00033 52_[+1]_20 chr16:50248010-50248090 0.00035 21_[+1]_51 chr2:159757923-159758003 0.00035 42_[+1]_30 chr6:70930811-70930891 0.00035 39_[+1]_33 chr7:50182081-50182161 0.00035 27_[+1]_45 chr19:1848787-1848867 0.00039 72_[+1] chr6:15107300-15107380 0.00039 44_[+1]_28 chr1:218503534-218503614 0.00039 38_[+1]_34 chr6:158635334-158635414 0.00046 37_[+1]_35 chr1:246166596-246166676 0.00047 38_[+1]_34 chr6:168257891-168257971 0.00051 13_[+1]_59 chr6:11496593-11496673 0.00051 59_[+1]_13 chr16:53241808-53241888 0.00053 58_[+1]_14 chr6:10759737-10759817 0.00062 53_[+1]_19 chr16:20703115-20703195 0.00062 50_[+1]_22 chr15:67196139-67196219 0.00062 72_[+1] chr4:110899217-110899297 0.00062 48_[+1]_24 chr5:95000002-95000082 0.0007 26_[+1]_46 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGRKGGCR MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGRKGGCR width=8 seqs=106 chr6:42629458-42629538 ( 23) AGGGGGCG 1 chr9:90788477-90788557 ( 8) AGGGGGCG 1 chr10:27512963-27513043 ( 43) AGGGGGCG 1 chr1:86965828-86965908 ( 42) AGGGGGCG 1 chr22:22785980-22786060 ( 32) AGAGGGCG 1 chr7:104621836-104621916 ( 17) AGAGGGCG 1 chr19:54345495-54345575 ( 25) AGAGGGCG 1 chr4:68612585-68612665 ( 24) AGAGGGCG 1 chr12:27168768-27168848 ( 46) AGAGGGCG 1 chr11:82578657-82578737 ( 60) AGAGGGCG 1 chr12:122820729-12282080 ( 36) AGAGGGCG 1 chr1:212236330-212236410 ( 54) AGGGGGCA 1 chr6:26176039-26176119 ( 54) AGGGGGCA 1 chr1:54535900-54535980 ( 17) AGGGGGCA 1 chr6:138121224-138121304 ( 49) AGGGGGCA 1 chr20:58524331-58524411 ( 19) AGGTGGCG 1 chr5:154325374-154325454 ( 68) AGAGGGCA 1 chr2:113842002-113842082 ( 35) AGAGGGCA 1 chr10:11824962-11825042 ( 22) AGAGGGCA 1 chr1:46710730-46710810 ( 23) AGAGGGCA 1 chr11:32334583-32334663 ( 14) AGAGGGCA 1 chr6:131961894-131961974 ( 14) AGAGGGCA 1 chr8:110359245-110359325 ( 39) AGAGGGCA 1 chr6:127624055-127624135 ( 26) AGAGGGCA 1 chr7:116628571-116628651 ( 55) AGAGGGCA 1 chr1:44229255-44229335 ( 38) AGAGGGCA 1 chr7:123134394-123134474 ( 43) AGAGGGCA 1 chr16:70563442-70563522 ( 52) AGAGGGCA 1 chr2:179261897-179261977 ( 32) AGATGGCG 1 chr6:71416366-71416446 ( 50) AGATGGCG 1 chr18:3281610-3281690 ( 4) AGGTGGCA 1 chr5:80809985-80810065 ( 32) AGGTGGCA 1 chr7:7143155-7143235 ( 34) AGGTGGCA 1 chr20:43948321-43948401 ( 44) AGGTGGCA 1 chrX:11551430-11551510 ( 14) AGGTGGCA 1 chr11:33187924-33188004 ( 28) AGGTGGCA 1 chr4:79533712-79533792 ( 35) AGGTGGCA 1 chr1:233500587-233500667 ( 51) AGATGGCA 1 chr6:157735906-157735986 ( 55) AGATGGCA 1 chr1:93324584-93324664 ( 12) AGATGGCA 1 chr6:36986489-36986569 ( 52) AGATGGCA 1 chr1:26929007-26929087 ( 31) AGATGGCA 1 chr6:593291-593371 ( 36) AGATGGCA 1 chr1:114378469-114378549 ( 33) AGATGGCA 1 chr1:172398592-172398672 ( 39) AGATGGCA 1 chr11:61564820-61564900 ( 22) AGATGGCA 1 chr6:15327618-15327698 ( 57) AGGGGGAG 1 chr2:31085088-31085168 ( 9) AGGGGGAG 1 chr14:31449440-31449520 ( 9) TGGGGGCG 1 chr5:72792922-72793002 ( 49) AGGGGGAG 1 chr11:46299093-46299173 ( 64) TGGGGGCG 1 chrX:65330126-65330206 ( 19) AGGGGGAG 1 chr1:173224483-173224563 ( 51) AGGGGGAG 1 chr6:153185152-153185232 ( 40) TGAGGGCG 1 chr17:38115318-38115398 ( 55) AGAGGGAG 1 chr6:116589835-116589915 ( 5) AGAGGGAG 1 chr1:33936229-33936309 ( 16) TGAGGGCG 1 chr10:45504151-45504231 ( 13) TGAGGGCG 1 chr3:185178679-185178759 ( 22) AGAGGGAG 1 chr10:73886102-73886182 ( 37) AGAGGGAG 1 chr7:130380813-130380893 ( 25) AGAGGGAG 1 chr22:20863808-20863888 ( 20) AGGGGGAA 1 chr22:22067610-22067690 ( 26) AGGGGGAA 1 chr4:39697455-39697535 ( 39) AGGGGGCT 1 chr10:70982118-70982198 ( 42) AGGAGGCG 1 chr12:121916876-12191695 ( 30) AGGAGGCG 1 chr19:3719185-3719265 ( 55) TGGTGGCG 1 chr11:10780687-10780767 ( 16) AGGTGGAG 1 chr15:51995045-51995125 ( 47) AGGTGGAG 1 chr22:22302167-22302247 ( 5) AGAGGGCT 1 chr5:137371790-137371870 ( 27) AGGGGGTG 1 chr19:1601800-1601880 ( 51) AGAGGGCT 1 chr2:86429234-86429314 ( 42) AGAAGGCG 1 chr9:108371453-108371533 ( 21) TGATGGCG 1 chr3:5809096-5809176 ( 53) AGATGGAG 1 chr15:50886687-50886767 ( 24) AGGAGGCA 1 chr6:116832661-116832741 ( 12) AGGAGGCA 1 chr7:101151229-101151309 ( 48) TGATGGCG 1 chr6:74362458-74362538 ( 13) AGATGGAG 1 chr18:8654649-8654729 ( 45) AGGAGGCA 1 chr19:48948671-48948751 ( 9) AGAGGGTG 1 chr1:29360509-29360589 ( 16) AGGTGGCT 1 chr2:188364821-188364901 ( 41) TGGTGGCA 1 chr5:54686479-54686559 ( 67) AGGTGGAA 1 chr7:140175705-140175785 ( 37) TGGTGGCA 1 chr16:67383241-67383321 ( 36) AGGGGGCC 1 chr4:147263912-147263992 ( 26) AGGTGGTG 1 chr17:44290409-44290489 ( 7) AGATGGAA 1 chr3:167765172-167765252 ( 53) AGATGGCT 1 chr16:50248010-50248090 ( 22) AGAGGGTA 1 chr2:159757923-159758003 ( 43) AGAGGGTA 1 chr6:70930811-70930891 ( 40) AGAGGGTA 1 chr7:50182081-50182161 ( 28) AGAGGGCC 1 chr19:1848787-1848867 ( 73) AGGTGGCC 1 chr6:15107300-15107380 ( 45) AGGTGGTA 1 chr1:218503534-218503614 ( 39) AGGTGGTA 1 chr6:158635334-158635414 ( 38) AGGAGGAG 1 chr1:246166596-246166676 ( 39) TGGTGGAG 1 chr6:168257891-168257971 ( 14) TGGGGGTG 1 chr6:11496593-11496673 ( 60) TGAGGGCT 1 chr16:53241808-53241888 ( 59) AGAAGGAG 1 chr6:10759737-10759817 ( 54) TGGTGGCT 1 chr16:20703115-20703195 ( 51) TGGTGGAA 1 chr15:67196139-67196219 ( 73) TGGTGGCT 1 chr4:110899217-110899297 ( 49) TGGTGGCT 1 chr5:95000002-95000082 ( 27) AGGAGGTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGRKGGCR MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.54487 E= 1.8e-067 152 -1337 -1337 -89 -1337 -1337 229 -1337 80 -1337 126 -1337 -178 -1337 137 38 -1337 -1337 229 -1337 -1337 -1337 229 -1337 -49 175 -1337 -165 60 -287 112 -180 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGRKGGCR MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 106 E= 1.8e-067 0.839623 0.000000 0.000000 0.160377 0.000000 0.000000 1.000000 0.000000 0.509434 0.000000 0.490566 0.000000 0.084906 0.000000 0.528302 0.386792 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.207547 0.698113 0.000000 0.094340 0.443396 0.028302 0.443396 0.084906 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGRKGGCR MEME-1 regular expression -------------------------------------------------------------------------------- AG[AG][GT]GG[CA][AG] -------------------------------------------------------------------------------- Time 5.07 secs. ******************************************************************************** ******************************************************************************** MOTIF YGCCMYCT MEME-2 width = 8 sites = 68 llr = 563 E-value = 5.1e-036 ******************************************************************************** -------------------------------------------------------------------------------- Motif YGCCMYCT MEME-2 Description -------------------------------------------------------------------------------- Simplified A :2::5::: pos.-specific C 6:aa55a: probability G :6:::::: matrix T 32:::5:9 bits 2.3 ** * 2.1 ** * 1.8 ** * 1.6 ** * Relative 1.4 ** ** Entropy 1.1 *** ** (11.9 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CGCCCCCT consensus T AT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGCCMYCT MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr15:65596707-65596787 27 4.75e-06 TCTTCGGCTT CGCCCCCT AACGGTGACA chr9:90788477-90788557 58 4.75e-06 ATAATGAGAG CGCCCCCT ACACTCAATT chr7:123357077-123357157 61 4.75e-06 ATTTCTCTAA CGCCCCCT TTTGGTTTGT chr19:3719185-3719265 45 1.82e-05 TGATTTTTTG CGCCACCT GCTGGTGGCG chr6:27720181-27720261 27 1.82e-05 gtctctccat cgccctct attgacaaaa chr19:1848787-1848867 40 1.82e-05 CACCTTAAGG CGCCCTCT GCTGGACGAG chr11:46299093-46299173 22 1.82e-05 CCTCGAGCCA CGCCCTCT TCTCATTAAT chr1:33936229-33936309 29 1.82e-05 GGGCGAGGCG CGCCCTCT TGTGTCCTAA chr7:20351211-20351291 42 1.82e-05 AGCTCTTGGC CGCCACCT AAAGGTTTAT chr10:74820959-74821039 43 1.82e-05 aagttcatag cgccacct atggagttaa chr6:125435570-125435650 16 1.82e-05 TATGATTTGG CGCCCTCT GATGTTCATC chr9:116639204-116639284 31 1.82e-05 ATTAAAACGA CGCCACCT AGAGGATACT chr3:194125522-194125602 38 1.82e-05 TGACCTCTGG CGCCACCT AATGGCATAA chr17:27618312-27618392 36 1.82e-05 CCTTCTCTTG CGCCCTCT TCTGGATTAA chr13:92374712-92374792 29 1.82e-05 AATGCAGAAG CGCCCTCT GGTGGTTTAA chr7:130380813-130380893 59 1.82e-05 TATTGAAAGT CGCCCTCT GATGGTGACA chr8:121096976-121097056 37 2.50e-05 TATGAAATGC TGCCCCCT TGTGTTTTTG chr6:147106296-147106376 20 2.50e-05 AACCATGTGC TGCCCCCT TGTGGAATAT chr1:24853813-24853893 42 2.50e-05 ATCTTAAAAC TGCCCCCT GCTGGAAGCA chr7:43878654-43878734 41 2.50e-05 GGTGGCCGCG TGCCCCCT CCTGGCTGTC chr6:109704573-109704653 22 3.46e-05 TAAAGGTGAG CGCCATCT ACTGCCAAGT chr2:167038247-167038327 26 3.46e-05 tacgcgccgt cgccatct actggatcaa chr6:135323499-135323579 49 5.39e-05 TGGTTACCTC TGCCACCT AGTGGTATAA chr11:22809268-22809348 39 5.39e-05 AATGTGCTGC TGCCACCT AGTGCTTAGA chr7:111126781-111126861 25 5.39e-05 AGTGAAACAG TGCCACCT TTTGGACCCA chr4:74312212-74312292 54 5.39e-05 ATCTATAGAC TGCCCTCT GAAGGTCATA chr2:152664987-152665067 27 5.39e-05 TTAATTACAG TGCCCTCT GCAGGATGGC chr6:4008774-4008854 52 5.39e-05 GGTCCTTTGC TGCCCTCT TATGGAAGAT chr17:58716256-58716336 24 5.39e-05 GTAGCAAAGG TGCCCTCT AGTGGCTGCC chr22:21138672-21138752 64 5.39e-05 GGGACACATC TGCCCTCT AGGGGCCAG chr1:7813039-7813119 19 5.39e-05 AGATAGCTGG TGCCCTCT GCTGGTCATG chr6:74362458-74362538 30 5.39e-05 GCTATAAGGT TGCCACCT CTACTGCCAC chr7:123177237-123177317 68 5.39e-05 TTTACAAAGA TGCCACCT AGTGG chr8:101950951-101951031 26 6.08e-05 TAATCTCTTA CTCCCCCT TGTGGCCGGA chr17:44290409-44290489 39 6.08e-05 GCAACTGCAG CTCCCCCT GCTGACAGAT chr11:82638473-82638553 31 6.08e-05 AGATTTTAGA CTCCCCCT AGTGGCCATC chr7:128099518-128099598 30 6.76e-05 TGTGTGCCAC CAccccct tgtggttgga chr6:37621851-37621931 19 8.13e-05 TTATTCCTTC TGCCATCT GCTGGCAGTT chr15:101112778-10111285 12 8.13e-05 ATATAACAGG TGCCATCT AGTGTTATAA chr4:110899217-110899297 28 8.13e-05 ATTATTACAG TGCCATCT ACTGGTATAT chr7:105070305-105070385 38 1.01e-04 ACAGCCATGT CTCCCTCT GCTGGCTGAG chr5:36870691-36870771 44 1.01e-04 ATTGACTTGG CTCCCTCT GCTGGTTAGT chr22:20015636-20015716 25 1.01e-04 gagacagagt ctccctct gttgctgtgt chr8:125966101-125966181 24 1.01e-04 GCAATGTCAG CTCCCTCT GGTGGGCTGA chr7:128938255-128938335 32 1.01e-04 TAGAAACTGT CTCCACCT GCTGGCCGCA chr6:11496593-11496673 19 1.01e-04 TAGGGGTTGG CTCCACCT GGTGCTTTGA chr1:246614177-246614257 72 1.20e-04 ATGACTCTAC CACCACCT A chr3:160061111-160061191 19 1.20e-04 CAAGCAATAG CACCACCT GCTGATAGAT chr7:157043462-157043542 29 1.20e-04 CTAGGTCTTG CACCACCT AGTGGCCTGA chr4:56602952-56603032 28 1.20e-04 TATTTCAGAG CACCACCT GGTGGATTAA chr22:30485033-30485113 71 1.20e-04 TAATCTCTAT CACCACCT TG chr8:54923145-54923225 34 1.20e-04 GGAGCAACAG CACCACCT ATAGCTTACA chr4:129141602-129141682 25 1.44e-04 AGACCTCTTA CTCCATCT TGTGGTGATA chr7:106716510-106716590 73 1.44e-04 gctctctcct ctccatct chr15:42792338-42792418 33 1.57e-04 GGCTTTCCCC CGCCCCCG CCCCAATTTG chr5:86696300-86696380 33 1.57e-04 TTTTAAAGTG TACCCCCT AGTGGTATAA chr16:53241808-53241888 35 1.71e-04 TAACTGGTAG CACCATCT GCTGGCCTAC chr1:29360509-29360589 39 1.71e-04 GTGTATATAT CACCATCT GCTGGTGAAT chr6:56886029-56886109 56 1.71e-04 TCAGATATAG CACCATCT AGTGGAATAC chr1:235764542-235764622 40 1.77e-04 CTAAAAGAGG AGCCCCCT AGTGgtgctc chr12:120667057-12066713 2 2.66e-04 C CGCCCCCA CCCCCGACTG chr10:70982118-70982198 22 2.66e-04 TTAGATTCAG AGCCCTCT ACTGGCTACT chr12:118795683-11879576 40 2.66e-04 GAAAGAATAG CGCCCCCA TTAGTAATAT chr1:28743179-28743259 11 2.86e-04 ATGGACTGGT TTCCATCT GAATTTATTG chr11:33187924-33188004 48 2.86e-04 CAAATACAAT TTCCATCT AACAATTAAA chr14:51327361-51327441 39 2.91e-04 AGCTCACTGC TGCCCCCG CGTGTCTGAT chr3:167765172-167765252 16 3.44e-04 AAGCCAGCCA AGCCATCT TTAATGCTTT chr2:31085088-31085168 49 3.57e-04 TCTTCACTCC TGCCACCG TGTGGACAGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGCCMYCT MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr15:65596707-65596787 4.8e-06 26_[+2]_46 chr9:90788477-90788557 4.8e-06 57_[+2]_15 chr7:123357077-123357157 4.8e-06 60_[+2]_12 chr19:3719185-3719265 1.8e-05 44_[+2]_28 chr6:27720181-27720261 1.8e-05 26_[+2]_46 chr19:1848787-1848867 1.8e-05 39_[+2]_33 chr11:46299093-46299173 1.8e-05 21_[+2]_51 chr1:33936229-33936309 1.8e-05 28_[+2]_44 chr7:20351211-20351291 1.8e-05 41_[+2]_31 chr10:74820959-74821039 1.8e-05 42_[+2]_30 chr6:125435570-125435650 1.8e-05 15_[+2]_57 chr9:116639204-116639284 1.8e-05 30_[+2]_42 chr3:194125522-194125602 1.8e-05 37_[+2]_35 chr17:27618312-27618392 1.8e-05 35_[+2]_37 chr13:92374712-92374792 1.8e-05 28_[+2]_44 chr7:130380813-130380893 1.8e-05 58_[+2]_14 chr8:121096976-121097056 2.5e-05 36_[+2]_36 chr6:147106296-147106376 2.5e-05 19_[+2]_53 chr1:24853813-24853893 2.5e-05 41_[+2]_31 chr7:43878654-43878734 2.5e-05 40_[+2]_32 chr6:109704573-109704653 3.5e-05 21_[+2]_51 chr2:167038247-167038327 3.5e-05 25_[+2]_47 chr6:135323499-135323579 5.4e-05 48_[+2]_24 chr11:22809268-22809348 5.4e-05 38_[+2]_34 chr7:111126781-111126861 5.4e-05 24_[+2]_48 chr4:74312212-74312292 5.4e-05 53_[+2]_19 chr2:152664987-152665067 5.4e-05 26_[+2]_46 chr6:4008774-4008854 5.4e-05 51_[+2]_21 chr17:58716256-58716336 5.4e-05 23_[+2]_49 chr22:21138672-21138752 5.4e-05 63_[+2]_9 chr1:7813039-7813119 5.4e-05 18_[+2]_54 chr6:74362458-74362538 5.4e-05 29_[+2]_43 chr7:123177237-123177317 5.4e-05 67_[+2]_5 chr8:101950951-101951031 6.1e-05 25_[+2]_47 chr17:44290409-44290489 6.1e-05 38_[+2]_34 chr11:82638473-82638553 6.1e-05 30_[+2]_42 chr7:128099518-128099598 6.8e-05 29_[+2]_43 chr6:37621851-37621931 8.1e-05 18_[+2]_54 chr15:101112778-10111285 8.1e-05 11_[+2]_61 chr4:110899217-110899297 8.1e-05 27_[+2]_45 chr7:105070305-105070385 0.0001 37_[+2]_35 chr5:36870691-36870771 0.0001 43_[+2]_29 chr22:20015636-20015716 0.0001 24_[+2]_48 chr8:125966101-125966181 0.0001 23_[+2]_49 chr7:128938255-128938335 0.0001 31_[+2]_41 chr6:11496593-11496673 0.0001 18_[+2]_54 chr1:246614177-246614257 0.00012 71_[+2]_1 chr3:160061111-160061191 0.00012 18_[+2]_54 chr7:157043462-157043542 0.00012 28_[+2]_44 chr4:56602952-56603032 0.00012 27_[+2]_45 chr22:30485033-30485113 0.00012 70_[+2]_2 chr8:54923145-54923225 0.00012 33_[+2]_39 chr4:129141602-129141682 0.00014 24_[+2]_48 chr7:106716510-106716590 0.00014 72_[+2] chr15:42792338-42792418 0.00016 32_[+2]_40 chr5:86696300-86696380 0.00016 32_[+2]_40 chr16:53241808-53241888 0.00017 34_[+2]_38 chr1:29360509-29360589 0.00017 38_[+2]_34 chr6:56886029-56886109 0.00017 55_[+2]_17 chr1:235764542-235764622 0.00018 39_[+2]_33 chr12:120667057-12066713 0.00027 1_[+2]_71 chr10:70982118-70982198 0.00027 21_[+2]_51 chr12:118795683-11879576 0.00027 39_[+2]_33 chr1:28743179-28743259 0.00029 10_[+2]_62 chr11:33187924-33188004 0.00029 47_[+2]_25 chr14:51327361-51327441 0.00029 38_[+2]_34 chr3:167765172-167765252 0.00034 15_[+2]_57 chr2:31085088-31085168 0.00036 48_[+2]_24 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGCCMYCT MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YGCCMYCT width=8 seqs=68 chr15:65596707-65596787 ( 27) CGCCCCCT 1 chr9:90788477-90788557 ( 58) CGCCCCCT 1 chr7:123357077-123357157 ( 61) CGCCCCCT 1 chr19:3719185-3719265 ( 45) CGCCACCT 1 chr6:27720181-27720261 ( 27) CGCCCTCT 1 chr19:1848787-1848867 ( 40) CGCCCTCT 1 chr11:46299093-46299173 ( 22) CGCCCTCT 1 chr1:33936229-33936309 ( 29) CGCCCTCT 1 chr7:20351211-20351291 ( 42) CGCCACCT 1 chr10:74820959-74821039 ( 43) CGCCACCT 1 chr6:125435570-125435650 ( 16) CGCCCTCT 1 chr9:116639204-116639284 ( 31) CGCCACCT 1 chr3:194125522-194125602 ( 38) CGCCACCT 1 chr17:27618312-27618392 ( 36) CGCCCTCT 1 chr13:92374712-92374792 ( 29) CGCCCTCT 1 chr7:130380813-130380893 ( 59) CGCCCTCT 1 chr8:121096976-121097056 ( 37) TGCCCCCT 1 chr6:147106296-147106376 ( 20) TGCCCCCT 1 chr1:24853813-24853893 ( 42) TGCCCCCT 1 chr7:43878654-43878734 ( 41) TGCCCCCT 1 chr6:109704573-109704653 ( 22) CGCCATCT 1 chr2:167038247-167038327 ( 26) CGCCATCT 1 chr6:135323499-135323579 ( 49) TGCCACCT 1 chr11:22809268-22809348 ( 39) TGCCACCT 1 chr7:111126781-111126861 ( 25) TGCCACCT 1 chr4:74312212-74312292 ( 54) TGCCCTCT 1 chr2:152664987-152665067 ( 27) TGCCCTCT 1 chr6:4008774-4008854 ( 52) TGCCCTCT 1 chr17:58716256-58716336 ( 24) TGCCCTCT 1 chr22:21138672-21138752 ( 64) TGCCCTCT 1 chr1:7813039-7813119 ( 19) TGCCCTCT 1 chr6:74362458-74362538 ( 30) TGCCACCT 1 chr7:123177237-123177317 ( 68) TGCCACCT 1 chr8:101950951-101951031 ( 26) CTCCCCCT 1 chr17:44290409-44290489 ( 39) CTCCCCCT 1 chr11:82638473-82638553 ( 31) CTCCCCCT 1 chr7:128099518-128099598 ( 30) CACCCCCT 1 chr6:37621851-37621931 ( 19) TGCCATCT 1 chr15:101112778-10111285 ( 12) TGCCATCT 1 chr4:110899217-110899297 ( 28) TGCCATCT 1 chr7:105070305-105070385 ( 38) CTCCCTCT 1 chr5:36870691-36870771 ( 44) CTCCCTCT 1 chr22:20015636-20015716 ( 25) CTCCCTCT 1 chr8:125966101-125966181 ( 24) CTCCCTCT 1 chr7:128938255-128938335 ( 32) CTCCACCT 1 chr6:11496593-11496673 ( 19) CTCCACCT 1 chr1:246614177-246614257 ( 72) CACCACCT 1 chr3:160061111-160061191 ( 19) CACCACCT 1 chr7:157043462-157043542 ( 29) CACCACCT 1 chr4:56602952-56603032 ( 28) CACCACCT 1 chr22:30485033-30485113 ( 71) CACCACCT 1 chr8:54923145-54923225 ( 34) CACCACCT 1 chr4:129141602-129141682 ( 25) CTCCATCT 1 chr7:106716510-106716590 ( 73) CTCCATCT 1 chr15:42792338-42792418 ( 33) CGCCCCCG 1 chr5:86696300-86696380 ( 33) TACCCCCT 1 chr16:53241808-53241888 ( 35) CACCATCT 1 chr1:29360509-29360589 ( 39) CACCATCT 1 chr6:56886029-56886109 ( 56) CACCATCT 1 chr1:235764542-235764622 ( 40) AGCCCCCT 1 chr12:120667057-12066713 ( 2) CGCCCCCA 1 chr10:70982118-70982198 ( 22) AGCCCTCT 1 chr12:118795683-11879576 ( 40) CGCCCCCA 1 chr1:28743179-28743259 ( 11) TTCCATCT 1 chr11:33187924-33188004 ( 48) TTCCATCT 1 chr14:51327361-51327441 ( 39) TGCCCCCG 1 chr3:167765172-167765252 ( 16) AGCCATCT 1 chr2:31085088-31085168 ( 49) TGCCACCG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGCCMYCT MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 9.8321 E= 5.1e-036 -273 158 -1273 19 -85 -1273 166 -63 -1273 227 -1273 -1273 -1273 227 -1273 -1273 69 135 -1273 -1273 -1273 135 -1273 67 -1273 227 -1273 -1273 -331 -1273 -221 164 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGCCMYCT MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 68 E= 5.1e-036 0.044118 0.617647 0.000000 0.338235 0.161765 0.000000 0.647059 0.191176 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.470588 0.529412 0.000000 0.000000 0.000000 0.529412 0.000000 0.470588 0.000000 1.000000 0.000000 0.000000 0.029412 0.000000 0.044118 0.926471 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YGCCMYCT MEME-2 regular expression -------------------------------------------------------------------------------- [CT]GCC[CA][CT]CT -------------------------------------------------------------------------------- Time 8.88 secs. ******************************************************************************** ******************************************************************************** MOTIF BCCWCYAG MEME-3 width = 8 sites = 27 llr = 236 E-value = 3.9e-001 ******************************************************************************** -------------------------------------------------------------------------------- Motif BCCWCYAG MEME-3 Description -------------------------------------------------------------------------------- Simplified A 1::6::a: pos.-specific C 3aa:95:: probability G 4:::1::a matrix T 3::4:5:: bits 2.3 ** * 2.1 ** * 1.8 ** * ** 1.6 ** * ** Relative 1.4 ** * ** Entropy 1.1 ** * ** (12.6 bits) 0.9 ******* 0.7 ******* 0.5 ******* 0.2 ******** 0.0 -------- Multilevel GCCACCAG consensus T T T sequence C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BCCWCYAG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:125513580-125513660 54 6.51e-06 ACATCATCTG GCCACCAG GGGTTGTGCT chr1:182226608-182226688 31 1.31e-05 TCTCACCACT CCCACCAG CAGGTTAAGG chr1:229850954-229851034 21 1.31e-05 atgagacact cccaccag caccatgatc chr1:242183272-242183352 47 2.90e-05 TGGTAATTTG GCCACTAG ATGTCACACC chr12:123278358-12327843 21 2.90e-05 GTGGTATTCT GCCACTAG AGGTCACTAT chr6:28400989-28401069 31 2.90e-05 GTGATATAAT GCCTCCag tggcttaata chr16:25850204-25850284 18 2.90e-05 TGCCTTCCCT GCCACTAG GTGTCACTGT chr1:100194490-100194570 3 2.90e-05 tg gccactag tatacaatca chr10:62528766-62528846 34 2.90e-05 TTACGGCATA GCCTCCAG ATTAAacaca chr1:7813039-7813119 3 3.85e-05 TT TCCACCAG ATAGCTGGTG chr7:128503706-128503786 29 3.85e-05 ATGCTTTTAA TCCACCAG GGGTCCTGGT chr6:116832661-116832741 3 3.85e-05 TT TCCACCAG TAGGAGGCAT chr1:54535900-54535980 57 3.85e-05 ATAAAGTATT TCCACCAG TAGAGGGTAC chr6:10759737-10759817 46 5.47e-05 aatttatcct cccactag tggtgGCTTT chr5:137516033-137516113 31 5.47e-05 ttggcattta cccactag atgtcagtag chr12:104647320-10464740 15 6.41e-05 GTAATTCTTG GCCTCTAG GGGCTTAATT chr6:27720181-27720261 5 8.72e-05 tatt tcctccag caatgtctct chr18:8654649-8654729 36 8.72e-05 ATACAAAATT TCCACTAG GAGGAGGCAG chr1:151224342-151224422 29 9.68e-05 ATCAGAGGGT CCCTCTAG CGGTGAGCAG chr3:44277600-44277680 25 9.68e-05 TGATCTGGGG CCCTCTAG TGGATACAAA chr7:101151229-101151309 56 9.68e-05 tatgatggcg ccctctag ggttgtgcaa chr4:26721731-26721811 37 1.10e-04 TGCTATTGCT TCCTCTAG TGGGAAGTGA chr4:124017374-124017454 2 1.10e-04 G TCCTCTAG TGTTCATTTT chr15:67196139-67196219 13 1.20e-04 TCTCAATACG ACCACCAG AGGCGGCATT chr7:7144119-7144199 64 1.49e-04 TTCTCTGAGA ACCTCCAG ATTAGGTTA chr2:188364821-188364901 32 1.49e-04 GAGTAATTTT GCCAGCAG GTGGTGGCAG chr19:51524428-51524508 34 1.49e-04 taccatattg gccagcAG AGGTCTCCAC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BCCWCYAG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:125513580-125513660 6.5e-06 53_[+3]_19 chr1:182226608-182226688 1.3e-05 30_[+3]_42 chr1:229850954-229851034 1.3e-05 20_[+3]_52 chr1:242183272-242183352 2.9e-05 46_[+3]_26 chr12:123278358-12327843 2.9e-05 20_[+3]_52 chr6:28400989-28401069 2.9e-05 30_[+3]_42 chr16:25850204-25850284 2.9e-05 17_[+3]_55 chr1:100194490-100194570 2.9e-05 2_[+3]_70 chr10:62528766-62528846 2.9e-05 33_[+3]_39 chr1:7813039-7813119 3.8e-05 2_[+3]_70 chr7:128503706-128503786 3.8e-05 28_[+3]_44 chr6:116832661-116832741 3.8e-05 2_[+3]_70 chr1:54535900-54535980 3.8e-05 56_[+3]_16 chr6:10759737-10759817 5.5e-05 45_[+3]_27 chr5:137516033-137516113 5.5e-05 30_[+3]_42 chr12:104647320-10464740 6.4e-05 14_[+3]_58 chr6:27720181-27720261 8.7e-05 4_[+3]_68 chr18:8654649-8654729 8.7e-05 35_[+3]_37 chr1:151224342-151224422 9.7e-05 28_[+3]_44 chr3:44277600-44277680 9.7e-05 24_[+3]_48 chr7:101151229-101151309 9.7e-05 55_[+3]_17 chr4:26721731-26721811 0.00011 36_[+3]_36 chr4:124017374-124017454 0.00011 1_[+3]_71 chr15:67196139-67196219 0.00012 12_[+3]_60 chr7:7144119-7144199 0.00015 63_[+3]_9 chr2:188364821-188364901 0.00015 31_[+3]_41 chr19:51524428-51524508 0.00015 33_[+3]_39 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BCCWCYAG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF BCCWCYAG width=8 seqs=27 chr6:125513580-125513660 ( 54) GCCACCAG 1 chr1:182226608-182226688 ( 31) CCCACCAG 1 chr1:229850954-229851034 ( 21) CCCACCAG 1 chr1:242183272-242183352 ( 47) GCCACTAG 1 chr12:123278358-12327843 ( 21) GCCACTAG 1 chr6:28400989-28401069 ( 31) GCCTCCAG 1 chr16:25850204-25850284 ( 18) GCCACTAG 1 chr1:100194490-100194570 ( 3) GCCACTAG 1 chr10:62528766-62528846 ( 34) GCCTCCAG 1 chr1:7813039-7813119 ( 3) TCCACCAG 1 chr7:128503706-128503786 ( 29) TCCACCAG 1 chr6:116832661-116832741 ( 3) TCCACCAG 1 chr1:54535900-54535980 ( 57) TCCACCAG 1 chr6:10759737-10759817 ( 46) CCCACTAG 1 chr5:137516033-137516113 ( 31) CCCACTAG 1 chr12:104647320-10464740 ( 15) GCCTCTAG 1 chr6:27720181-27720261 ( 5) TCCTCCAG 1 chr18:8654649-8654729 ( 36) TCCACTAG 1 chr1:151224342-151224422 ( 29) CCCTCTAG 1 chr3:44277600-44277680 ( 25) CCCTCTAG 1 chr7:101151229-101151309 ( 56) CCCTCTAG 1 chr4:26721731-26721811 ( 37) TCCTCTAG 1 chr4:124017374-124017454 ( 2) TCCTCTAG 1 chr15:67196139-67196219 ( 13) ACCACCAG 1 chr7:7144119-7144199 ( 64) ACCTCCAG 1 chr2:188364821-188364901 ( 32) GCCAGCAG 1 chr19:51524428-51524508 ( 34) GCCAGCAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BCCWCYAG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 11.0506 E= 3.9e-001 -198 32 86 0 -1140 227 -1140 -1140 -1140 227 -1140 -1140 111 -1140 -1140 32 -1140 216 -146 -1140 -1140 132 -1140 70 177 -1140 -1140 -1140 -1140 -1140 229 -1140 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BCCWCYAG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 27 E= 3.9e-001 0.074074 0.259259 0.370370 0.296296 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.629630 0.000000 0.000000 0.370370 0.000000 0.925926 0.074074 0.000000 0.000000 0.518519 0.000000 0.481481 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BCCWCYAG MEME-3 regular expression -------------------------------------------------------------------------------- [GTC]CC[AT]C[CT]AG -------------------------------------------------------------------------------- Time 12.47 secs. ******************************************************************************** ******************************************************************************** MOTIF GAGTCAKM MEME-4 width = 8 sites = 14 llr = 134 E-value = 1.3e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif GAGTCAKM MEME-4 Description -------------------------------------------------------------------------------- Simplified A :a:::a:3 pos.-specific C ::::a::5 probability G a:a:::42 matrix T :::a::6: bits 2.3 * * * 2.1 * * * 1.8 ****** 1.6 ****** Relative 1.4 ****** Entropy 1.1 ****** (13.8 bits) 0.9 ******* 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel GAGTCATC consensus GA sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGTCAKM MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr5:39399788-39399868 34 1.33e-05 AAGACTGCAT GAGTCATC TTAGAATGAC chr15:81391537-81391617 72 1.33e-05 AGGCTGCAGA GAGTCATC A chr2:65593862-65593942 51 1.33e-05 TGTACCGGAT GAGTCATC CGAGGGTTAG chr11:32334583-32334663 67 1.33e-05 ACCAGCCCAG GAGTCATC GCAGCC chr1:211722017-211722097 16 2.25e-05 CTGTGCTTCT GAGTCAGC AGCTCAATCA chr2:112676199-112676279 30 2.25e-05 TGAATGGTCT GAGTCAGC ATAATCAGTT chr8:121096976-121097056 4 2.25e-05 GCT GAGTCAGC ATTTATTTGT chr3:25645842-25645922 72 3.56e-05 ATAAGGAGTT GAGTCATG A chr2:106257927-106258007 31 3.56e-05 agtcaaaaat gagtcatg gctgccaaaa chr1:63004959-63005039 5 3.56e-05 TAAA GAGTCATG AGTAGGCCAG chr3:5809096-5809176 23 5.44e-05 gtattgggat gagtcata ttttctttat chr3:150215900-150215980 55 5.44e-05 aaattgggat gagtcata caatctgatg chr1:182226608-182226688 73 7.64e-05 CCCAGTATAG GAGTCAGA chr12:46825635-46825715 11 7.64e-05 CCATTAAATA GAGTCAGA GTGAAGTTAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGTCAKM MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:39399788-39399868 1.3e-05 33_[+4]_39 chr15:81391537-81391617 1.3e-05 71_[+4]_1 chr2:65593862-65593942 1.3e-05 50_[+4]_22 chr11:32334583-32334663 1.3e-05 66_[+4]_6 chr1:211722017-211722097 2.3e-05 15_[+4]_57 chr2:112676199-112676279 2.3e-05 29_[+4]_43 chr8:121096976-121097056 2.3e-05 3_[+4]_69 chr3:25645842-25645922 3.6e-05 71_[+4]_1 chr2:106257927-106258007 3.6e-05 30_[+4]_42 chr1:63004959-63005039 3.6e-05 4_[+4]_68 chr3:5809096-5809176 5.4e-05 22_[+4]_50 chr3:150215900-150215980 5.4e-05 54_[+4]_18 chr1:182226608-182226688 7.6e-05 72_[+4] chr12:46825635-46825715 7.6e-05 10_[+4]_62 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGTCAKM MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GAGTCAKM width=8 seqs=14 chr5:39399788-39399868 ( 34) GAGTCATC 1 chr15:81391537-81391617 ( 72) GAGTCATC 1 chr2:65593862-65593942 ( 51) GAGTCATC 1 chr11:32334583-32334663 ( 67) GAGTCATC 1 chr1:211722017-211722097 ( 16) GAGTCAGC 1 chr2:112676199-112676279 ( 30) GAGTCAGC 1 chr8:121096976-121097056 ( 4) GAGTCAGC 1 chr3:25645842-25645922 ( 72) GAGTCATG 1 chr2:106257927-106258007 ( 31) GAGTCATG 1 chr1:63004959-63005039 ( 5) GAGTCATG 1 chr3:5809096-5809176 ( 23) GAGTCATA 1 chr3:150215900-150215980 ( 55) GAGTCATA 1 chr1:182226608-182226688 ( 73) GAGTCAGA 1 chr12:46825635-46825715 ( 11) GAGTCAGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGTCAKM MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 10.1909 E= 1.3e+004 -1045 -1045 229 -1045 177 -1045 -1045 -1045 -1045 -1045 229 -1045 -1045 -1045 -1045 175 -1045 227 -1045 -1045 177 -1045 -1045 -1045 -1045 -1045 81 112 -3 127 7 -1045 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGTCAKM MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 14 E= 1.3e+004 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.357143 0.642857 0.285714 0.500000 0.214286 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GAGTCAKM MEME-4 regular expression -------------------------------------------------------------------------------- GAGTCA[TG][CAG] -------------------------------------------------------------------------------- Time 15.92 secs. ******************************************************************************** ******************************************************************************** MOTIF CATGGGGC MEME-5 width = 8 sites = 3 llr = 36 E-value = 8.1e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif CATGGGGC MEME-5 Description -------------------------------------------------------------------------------- Simplified A :a:::::: pos.-specific C a::::::a probability G :::aaaa: matrix T ::a::::: bits 2.3 * ***** 2.1 * ***** 1.8 ******** 1.6 ******** Relative 1.4 ******** Entropy 1.1 ******** (17.2 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CATGGGGC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGGGGC MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr15:81391537-81391617 7 6.41e-06 TTGGGG CATGGGGC GGGGTGTGTG chr6:26312026-26312106 12 6.41e-06 accattacac catggggc cAACAACACA chr6:26311424-26311504 63 6.41e-06 accattacac catggggc cGCCTTCCGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGGGGC MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr15:81391537-81391617 6.4e-06 6_[+5]_66 chr6:26312026-26312106 6.4e-06 11_[+5]_61 chr6:26311424-26311504 6.4e-06 62_[+5]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGGGGC MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CATGGGGC width=8 seqs=3 chr15:81391537-81391617 ( 7) CATGGGGC 1 chr6:26312026-26312106 ( 12) CATGGGGC 1 chr6:26311424-26311504 ( 63) CATGGGGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGGGGC MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 18250 bayes= 12.2293 E= 8.1e+004 -823 227 -823 -823 177 -823 -823 -823 -823 -823 -823 175 -823 -823 229 -823 -823 -823 229 -823 -823 -823 229 -823 -823 -823 229 -823 -823 227 -823 -823 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGGGGC MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 3 E= 8.1e+004 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGGGGC MEME-5 regular expression -------------------------------------------------------------------------------- CATGGGGC -------------------------------------------------------------------------------- Time 19.34 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:67521715-67521795 8.70e-01 80 chr18:8654649-8654729 4.04e-03 35_[+3(8.72e-05)]_37 chr10:62528766-62528846 3.31e-02 33_[+3(2.90e-05)]_39 chr2:175209880-175209960 5.58e-01 80 chr6:135772911-135772991 8.40e-01 80 chr2:167038247-167038327 9.98e-02 25_[+2(3.46e-05)]_47 chr1:218503534-218503614 8.34e-02 80 chr7:130380813-130380893 1.39e-03 24_[+1(8.88e-05)]_26_[+2(1.82e-05)]_\ 14 chr6:138121224-138121304 4.73e-04 48_[+1(1.68e-05)]_24 chr1:100194490-100194570 6.58e-02 2_[+3(2.90e-05)]_70 chr8:54923145-54923225 8.97e-02 80 chr16:67383241-67383321 2.43e-03 80 chr4:110899217-110899297 8.56e-03 27_[+2(8.13e-05)]_45 chr16:70563442-70563522 5.66e-04 51_[+1(3.21e-05)]_21 chr2:143792028-143792108 5.52e-01 80 chr1:86965828-86965908 8.62e-04 41_[+1(4.36e-06)]_31 chr13:92374712-92374792 9.93e-03 28_[+2(1.82e-05)]_44 chr5:137516033-137516113 4.98e-02 30_[+3(5.47e-05)]_42 chr12:94184689-94184769 2.64e-01 80 chr12:122820729-12282080 5.27e-04 35_[+1(1.06e-05)]_37 chr6:135410568-135410648 7.54e-01 80 chr7:86782777-86782857 6.28e-01 80 chr1:229850954-229851034 2.46e-02 20_[+3(1.31e-05)]_52 chr1:173224483-173224563 2.72e-03 50_[+1(7.37e-05)]_22 chrX:65330126-65330206 7.31e-02 18_[+1(7.37e-05)]_54 chr7:123134394-123134474 2.82e-03 42_[+1(3.21e-05)]_30 chr4:79533712-79533792 1.13e-02 34_[+1(5.02e-05)]_38 chr4:74123033-74123113 4.57e-01 80 chr11:33187924-33188004 2.86e-04 27_[+1(5.02e-05)]_45 chrX:11551430-11551510 1.18e-03 13_[+1(5.02e-05)]_59 chr7:123177237-123177317 4.88e-02 67_[+2(5.39e-05)]_5 chr3:167765172-167765252 1.65e-03 46_[+3(8.72e-05)]_26 chr7:43878654-43878734 9.03e-03 40_[+2(2.50e-05)]_32 chr6:74362458-74362538 6.37e-04 29_[+2(5.39e-05)]_43 chr20:43948321-43948401 3.02e-03 43_[+1(5.02e-05)]_29 chr1:54535900-54535980 5.25e-05 16_[+1(1.68e-05)]_32_[+3(3.85e-05)]_\ 16 chr7:101151229-101151309 9.39e-05 53_[+2(1.82e-05)]_19 chr11:82638473-82638553 3.61e-03 30_[+2(6.08e-05)]_42 chr2:113030388-113030468 1.76e-01 80 chr15:67196139-67196219 2.61e-04 65_[+2(5.39e-05)]_7 chr17:44290409-44290489 3.12e-03 38_[+2(6.08e-05)]_34 chr11:61564820-61564900 2.08e-02 21_[+1(6.31e-05)]_51 chr6:11496593-11496673 1.48e-03 80 chr11:82578657-82578737 8.68e-05 59_[+1(1.06e-05)]_13 chr19:51524428-51524508 7.22e-03 80 chr7:7143155-7143235 1.01e-02 33_[+1(5.02e-05)]_39 chr1:44229255-44229335 3.16e-03 37_[+1(3.21e-05)]_35 chr17:27618312-27618392 5.28e-02 35_[+2(1.82e-05)]_37 chr16:25850204-25850284 3.31e-02 17_[+3(2.90e-05)]_55 chr22:30485033-30485113 6.55e-02 80 chr7:128938255-128938335 1.43e-02 80 chr1:172398592-172398672 2.58e-02 38_[+1(6.31e-05)]_34 chr3:194125522-194125602 1.78e-02 37_[+2(1.82e-05)]_35 chr11:75785605-75785685 9.92e-01 80 chr6:116832661-116832741 5.52e-04 2_[+3(3.85e-05)]_70 chr1:114378469-114378549 1.53e-04 26_[+3(6.51e-06)]_46 chr5:80809985-80810065 4.55e-02 31_[+1(5.02e-05)]_41 chr20:58524331-58524411 4.92e-03 18_[+1(2.31e-05)]_54 chr6:593291-593371 2.12e-02 35_[+1(6.31e-05)]_37 chr19:1601800-1601880 1.61e-02 80 chr9:116639204-116639284 6.96e-02 30_[+2(1.82e-05)]_42 chr12:27168768-27168848 1.68e-02 45_[+1(1.06e-05)]_27 chr10:73886102-73886182 5.07e-02 36_[+1(8.88e-05)]_36 chr7:116628571-116628651 3.13e-02 54_[+1(3.21e-05)]_18 chr6:125435570-125435650 1.71e-03 15_[+2(1.82e-05)]_57 chr5:86696300-86696380 4.88e-02 80 chr6:127624055-127624135 4.63e-03 25_[+1(3.21e-05)]_47 chr3:185178679-185178759 1.76e-03 21_[+1(8.88e-05)]_51 chr6:28400989-28401069 4.79e-03 30_[+3(2.90e-05)]_42 chr7:128099518-128099598 9.94e-04 29_[+2(6.76e-05)]_43 chr8:110359245-110359325 3.05e-04 38_[+1(3.21e-05)]_24_[+5(3.72e-05)]_\ 2 chr16:56030117-56030197 9.61e-01 80 chr1:246166596-246166676 4.69e-03 31_[+2(3.46e-05)]_41 chr1:63004959-63005039 3.86e-02 4_[+4(3.56e-05)]_68 chr7:140175705-140175785 2.25e-01 80 chr7:128503706-128503786 2.45e-03 28_[+3(3.85e-05)]_44 chr2:86429234-86429314 1.05e-03 35_[+3(3.85e-05)]_37 chr6:26176039-26176119 9.34e-04 53_[+1(1.68e-05)]_19 chr7:50182081-50182161 1.56e-01 80 chr12:121916876-12191695 8.52e-02 80 chr10:27512963-27513043 6.88e-03 42_[+1(4.36e-06)]_30 chr6:131961894-131961974 9.40e-02 13_[+1(3.21e-05)]_59 chr10:22629229-22629309 8.18e-01 80 chr1:26929007-26929087 8.18e-02 30_[+1(6.31e-05)]_42 chr11:78125465-78125545 4.16e-01 80 chr1:7813039-7813119 1.62e-03 2_[+3(3.85e-05)]_8_[+2(5.39e-05)]_\ 54 chr8:125966101-125966181 6.08e-02 80 chr7:123357077-123357157 5.02e-03 60_[+2(4.75e-06)]_12 chr6:70930811-70930891 1.15e-02 80 chr6:36986489-36986569 4.76e-02 51_[+1(6.31e-05)]_21 chr10:74820959-74821039 1.86e-02 42_[+2(1.82e-05)]_30 chr1:93324584-93324664 2.99e-02 11_[+1(6.31e-05)]_61 chr1:43475158-43475238 4.85e-01 80 chr11:32334583-32334663 4.52e-05 13_[+1(3.21e-05)]_45_[+4(1.33e-05)]_\ 6 chr10:93672738-93672818 2.07e-01 80 chr7:20351211-20351291 6.36e-02 41_[+2(1.82e-05)]_31 chr12:104647320-10464740 6.26e-03 14_[+3(6.41e-05)]_58 chr4:39697455-39697535 1.46e-04 80 chr10:45504151-45504231 1.25e-01 12_[+1(8.88e-05)]_60 chr1:46710730-46710810 5.93e-04 22_[+1(3.21e-05)]_50 chr22:20015636-20015716 5.92e-02 80 chr4:68612585-68612665 1.44e-03 23_[+1(1.06e-05)]_49 chr15:42792338-42792418 3.74e-01 80 chr11:72158136-72158216 2.85e-01 80 chr4:124017374-124017454 5.78e-02 80 chr15:51995045-51995125 9.58e-02 80 chr6:157735906-157735986 4.09e-02 54_[+1(6.31e-05)]_18 chr5:36870691-36870771 2.07e-01 80 chr11:74170759-74170839 1.20e-01 80 chr15:101112778-10111285 1.32e-02 11_[+2(8.13e-05)]_61 chr4:74528562-74528642 4.90e-01 80 chr1:24853813-24853893 3.29e-02 41_[+2(2.50e-05)]_31 chr6:158635334-158635414 2.54e-02 80 chr6:15107300-15107380 1.66e-01 80 chr2:159757923-159758003 5.75e-02 80 chr1:33936229-33936309 3.20e-04 15_[+1(8.88e-05)]_5_[+2(1.82e-05)]_\ 44 chr9:37594628-37594708 2.46e-02 80 chr1:28743179-28743259 1.01e-01 80 chr6:71416366-71416446 7.16e-04 49_[+1(4.11e-05)]_23 chr6:116589835-116589915 1.54e-02 4_[+1(8.88e-05)]_68 chr6:91319277-91319357 8.30e-01 80 chr3:150215900-150215980 1.76e-02 54_[+4(5.44e-05)]_18 chr12:107173926-10717400 1.97e-02 80 chr3:44277600-44277680 9.88e-03 24_[+3(9.68e-05)]_48 chr22:21138672-21138752 8.78e-05 63_[+2(5.39e-05)]_9 chr2:32705195-32705275 9.99e-01 80 chr2:65593862-65593942 8.92e-02 50_[+4(1.33e-05)]_22 chr12:123278358-12327843 2.68e-02 20_[+3(2.90e-05)]_52 chr12:118795683-11879576 1.23e-01 80 chr5:95000002-95000082 1.63e-01 80 chr6:37621851-37621931 2.83e-02 18_[+2(8.13e-05)]_54 chr7:76012536-76012616 1.67e-01 80 chr11:46299093-46299173 5.78e-05 21_[+2(1.82e-05)]_34_[+1(7.37e-05)]_\ 9 chr18:3281610-3281690 1.49e-01 3_[+1(5.02e-05)]_69 chr2:106257927-106258007 9.91e-02 30_[+4(3.56e-05)]_42 chr1:241694761-241694841 2.74e-02 80 chr19:9906925-9907005 5.30e-01 80 chr5:72792922-72793002 6.46e-02 48_[+1(7.37e-05)]_24 chr9:90788477-90788557 5.21e-06 7_[+1(4.36e-06)]_42_[+2(4.75e-06)]_\ 15 chr11:6552641-6552721 2.29e-01 80 chr17:58716256-58716336 4.37e-04 23_[+2(5.39e-05)]_49 chr6:4008774-4008854 1.56e-01 51_[+2(5.39e-05)]_21 chr5:54686479-54686559 8.43e-02 80 chr4:68389161-68389241 9.52e-01 80 chr5:137371790-137371870 9.45e-02 80 chr19:1848787-1848867 8.13e-03 39_[+2(1.82e-05)]_33 chr1:36765676-36765756 6.63e-02 80 chr6:109704573-109704653 7.92e-02 21_[+2(3.46e-05)]_51 chr6:56886029-56886109 3.35e-02 80 chr2:152664987-152665067 3.34e-02 26_[+2(5.39e-05)]_46 chr4:147263912-147263992 1.57e-01 80 chr12:46119631-46119711 9.97e-02 80 chr4:56602952-56603032 2.29e-02 80 chr12:46825635-46825715 1.29e-02 10_[+4(7.64e-05)]_62 chr4:74312212-74312292 2.54e-02 53_[+2(5.39e-05)]_19 chr4:26721731-26721811 1.58e-02 80 chr19:54345495-54345575 1.48e-03 24_[+1(1.06e-05)]_48 chr7:111126781-111126861 3.43e-02 24_[+2(5.39e-05)]_48 chr22:22067610-22067690 1.42e-02 80 chr6:134478047-134478127 2.38e-01 80 chr14:51327361-51327441 1.43e-01 80 chr11:16301826-16301906 3.18e-01 80 chr11:22809268-22809348 1.12e-01 38_[+2(5.39e-05)]_34 chr6:26066313-26066393 4.54e-01 80 chr4:174139963-174140043 3.05e-01 80 chr15:50886687-50886767 1.12e-01 80 chr7:105070305-105070385 1.11e-01 80 chr10:70982118-70982198 2.67e-03 80 chr7:104621836-104621916 1.97e-02 16_[+1(1.06e-05)]_56 chr8:38243650-38243730 6.11e-01 80 chr14:31449440-31449520 5.91e-02 8_[+1(7.37e-05)]_64 chr3:37332897-37332977 7.68e-01 80 chr1:206990374-206990454 7.22e-01 80 chr15:92080112-92080192 4.25e-01 80 chr3:71257639-71257719 9.51e-01 80 chr1:242183272-242183352 3.77e-02 46_[+3(2.90e-05)]_26 chr6:147106296-147106376 1.51e-02 19_[+2(2.50e-05)]_53 chr17:25794487-25794567 6.69e-01 80 chr3:5809096-5809176 4.59e-04 22_[+4(5.44e-05)]_50 chr2:188364821-188364901 7.76e-03 80 chr9:100686086-100686166 9.58e-01 80 chr11:10780687-10780767 2.50e-02 80 chr6:27720181-27720261 4.46e-03 4_[+3(8.72e-05)]_14_[+2(1.82e-05)]_\ 46 chr6:150589016-150589096 3.90e-01 80 chr22:22785980-22786060 3.84e-04 31_[+1(1.06e-05)]_41 chr2:31085088-31085168 1.38e-03 8_[+1(7.37e-05)]_64 chr10:70977104-70977184 2.51e-01 80 chr8:103823820-103823900 6.86e-01 80 chr6:168247818-168247898 2.58e-01 80 chr1:29360509-29360589 3.40e-02 80 chr1:112312330-112312410 1.52e-01 80 chr7:106716510-106716590 1.05e-01 80 chr1:151224342-151224422 2.56e-02 28_[+3(9.68e-05)]_44 chr22:22302167-22302247 1.36e-01 80 chr7:7144119-7144199 7.27e-02 80 chr9:32943357-32943437 4.27e-01 80 chr10:11824962-11825042 1.08e-03 21_[+1(3.21e-05)]_51 chr6:7048389-7048469 4.54e-01 80 chr8:121096976-121097056 1.31e-03 3_[+4(2.25e-05)]_25_[+2(2.50e-05)]_\ 36 chr15:88162622-88162702 6.02e-01 80 chr4:129141602-129141682 1.13e-01 80 chr13:44833402-44833482 2.25e-01 80 chr6:15327618-15327698 1.15e-02 56_[+1(7.37e-05)]_16 chr1:75938237-75938317 2.96e-02 80 chr9:94807394-94807474 8.35e-01 80 chr17:41869151-41869231 9.56e-02 80 chr2:112676199-112676279 1.00e-01 29_[+4(2.25e-05)]_43 chr12:120667057-12066713 2.05e-01 80 chr7:157043462-157043542 4.24e-02 80 chr8:101950951-101951031 2.22e-02 25_[+2(6.08e-05)]_47 chr17:38115318-38115398 5.12e-03 54_[+1(8.88e-05)]_18 chr1:182226608-182226688 9.78e-04 30_[+3(1.31e-05)]_34_[+4(7.64e-05)] chr1:212236330-212236410 3.98e-06 53_[+1(1.68e-05)]_19 chr2:113842002-113842082 6.56e-02 34_[+1(3.21e-05)]_38 chr1:211722017-211722097 2.32e-03 15_[+4(2.25e-05)]_57 chr5:53685965-53686045 5.91e-03 80 chr3:160061111-160061191 1.34e-01 80 chr16:53241808-53241888 4.64e-03 80 chr6:26311424-26311504 7.58e-03 62_[+5(6.41e-06)]_10 chr15:66112178-66112258 3.54e-01 80 chr6:26312026-26312106 1.03e-02 11_[+5(6.41e-06)]_61 chr5:154325374-154325454 3.58e-02 67_[+1(3.21e-05)]_5 chr16:20703115-20703195 2.04e-02 80 chr6:10759737-10759817 1.12e-02 45_[+3(5.47e-05)]_27 chr16:50248010-50248090 2.95e-02 80 chr6:153185152-153185232 1.37e-02 39_[+1(8.88e-05)]_33 chr6:125513580-125513660 2.08e-03 53_[+3(6.51e-06)]_19 chr6:135323499-135323579 1.14e-01 48_[+2(5.39e-05)]_24 chr15:65596707-65596787 3.49e-03 26_[+2(4.75e-06)]_46 chr6:126267540-126267620 3.36e-01 80 chr15:81391537-81391617 5.30e-05 6_[+5(6.41e-06)]_57_[+4(1.33e-05)]_\ 1 chr9:108371453-108371533 1.48e-01 80 chr5:39399788-39399868 2.79e-02 33_[+4(1.33e-05)]_39 chr19:48948671-48948751 7.79e-03 2_[+3(2.90e-05)]_70 chr1:243610791-243610871 9.46e-01 80 chr6:42629458-42629538 6.92e-05 22_[+1(4.36e-06)]_50 chr19:3719185-3719265 1.07e-04 44_[+2(1.82e-05)]_28 chr15:39997046-39997126 5.04e-01 80 chr6:144126068-144126148 3.87e-01 80 chr3:25645842-25645922 1.43e-02 71_[+4(3.56e-05)]_1 chr2:179261897-179261977 9.14e-04 31_[+1(4.11e-05)]_41 chr6:49809283-49809363 6.42e-01 80 chr1:235764542-235764622 9.13e-03 80 chr14:50053665-50053745 1.26e-01 80 chr1:51986168-51986248 3.63e-03 12_[+5(3.72e-05)]_60 chr1:233500587-233500667 1.79e-02 50_[+1(6.31e-05)]_22 chr1:246614177-246614257 4.51e-02 80 chr6:168257891-168257971 9.23e-02 80 chr22:20863808-20863888 2.30e-01 80 chr2:68258832-68258912 4.21e-01 80 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n09.farnam.hpc.yale.internal ********************************************************************************