******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/YY1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr2:31456893-31456913 1.0000 20 chr2:62733050-62733070 1.0000 20 chr18:23501759-23501779 1.0000 20 chr1:161147243-161147263 1.0000 20 chr9:115819009-115819029 1.0000 20 chr16:1020935-1020955 1.0000 20 chr20:35374635-35374655 1.0000 20 chr8:120886001-120886021 1.0000 20 chr19:52552622-52552642 1.0000 20 chr1:223886100-223886120 1.0000 20 chr6:112350589-112350609 1.0000 20 chr5:139682640-139682660 1.0000 20 chr7:27200710-27200730 1.0000 20 chr19:7598952-7598972 1.0000 20 chrX:152127518-152127538 1.0000 20 chr19:19600120-19600140 1.0000 20 chr17:74732631-74732651 1.0000 20 chr5:5523404-5523424 1.0000 20 chr18:54318410-54318430 1.0000 20 chr1:35657757-35657777 1.0000 20 chr19:52408326-52408346 1.0000 20 chr17:4270110-4270130 1.0000 20 chrX:47880494-47880514 1.0000 20 chr12:72058031-72058051 1.0000 20 chr5:134073591-134073611 1.0000 20 chr5:140937536-140937556 1.0000 20 chr6:37467770-37467790 1.0000 20 chrX:47225800-47225820 1.0000 20 chr2:232316893-232316913 1.0000 20 chr6:29617595-29617615 1.0000 20 chr4:147443091-147443111 1.0000 20 chr1:78245253-78245273 1.0000 20 chr12:14538216-14538236 1.0000 20 chr5:134209989-134210009 1.0000 20 chr15:79165924-79165944 1.0000 20 chr7:100435091-100435111 1.0000 20 chr11:64015013-64015033 1.0000 20 chr20:45980523-45980543 1.0000 20 chr19:52511524-52511544 1.0000 20 chrX:47180910-47180930 1.0000 20 chr19:984365-984385 1.0000 20 chr12:32908778-32908798 1.0000 20 chr5:148929175-148929195 1.0000 20 chr6:117002369-117002389 1.0000 20 chr1:161129282-161129302 1.0000 20 chr7:128911765-128911785 1.0000 20 chrX:54556253-54556273 1.0000 20 chr17:16118841-16118861 1.0000 20 chr7:106239400-106239420 1.0000 20 chr8:145515311-145515331 1.0000 20 chr1:46152183-46152203 1.0000 20 chr19:49127403-49127423 1.0000 20 chr22:38902851-38902871 1.0000 20 chrX:63615397-63615417 1.0000 20 chrX:48455870-48455890 1.0000 20 chr15:93461261-93461281 1.0000 20 chr16:30546286-30546306 1.0000 20 chr12:15743471-15743491 1.0000 20 chr19:12886484-12886504 1.0000 20 chr17:3572121-3572141 1.0000 20 chr5:32174409-32174429 1.0000 20 chr1:75198863-75198883 1.0000 20 chr7:99686595-99686615 1.0000 20 chrX:47696132-47696152 1.0000 20 chr18:2571293-2571313 1.0000 20 chr2:128459108-128459128 1.0000 20 chr10:99393292-99393312 1.0000 20 chr2:86426615-86426635 1.0000 20 chr2:27357641-27357661 1.0000 20 chr16:68877452-68877472 1.0000 20 chr9:133569024-133569044 1.0000 20 chr14:23206502-23206522 1.0000 20 chr16:30773662-30773682 1.0000 20 chr17:42767094-42767114 1.0000 20 chr1:99646051-99646071 1.0000 20 chr11:10879342-10879362 1.0000 20 chr7:86782154-86782174 1.0000 20 chr6:43445319-43445339 1.0000 20 chr14:31494856-31494876 1.0000 20 chrX:24168516-24168536 1.0000 20 chr10:71267767-71267787 1.0000 20 chr19:50321393-50321413 1.0000 20 chr2:183989050-183989070 1.0000 20 chr3:185655220-185655240 1.0000 20 chr2:24583383-24583403 1.0000 20 chr11:74459925-74459945 1.0000 20 chr5:134074121-134074141 1.0000 20 chr11:67250517-67250537 1.0000 20 chr9:131965214-131965234 1.0000 20 chr11:34938220-34938240 1.0000 20 chr19:41945769-41945789 1.0000 20 chr15:41836424-41836444 1.0000 20 chr22:38578017-38578037 1.0000 20 chr11:45376959-45376979 1.0000 20 chr12:122492393-12249241 1.0000 20 chr7:5553486-5553506 1.0000 20 chr15:81282119-81282139 1.0000 20 chr5:176981628-176981648 1.0000 20 chr7:152456705-152456725 1.0000 20 chr2:105654550-105654570 1.0000 20 chr5:115420723-115420743 1.0000 20 chr19:10426645-10426665 1.0000 20 chr13:48575379-48575399 1.0000 20 chr7:25932633-25932653 1.0000 20 chrX:47342091-47342111 1.0000 20 chrX:152110225-152110245 1.0000 20 chrX:47863470-47863490 1.0000 20 chr19:1021095-1021115 1.0000 20 chr20:48552963-48552983 1.0000 20 chr10:104192378-10419239 1.0000 20 chr4:140216942-140216962 1.0000 20 chr19:2270762-2270782 1.0000 20 chr5:140699957-140699977 1.0000 20 chr2:15701420-15701440 1.0000 20 chr2:234475386-234475406 1.0000 20 chr20:3762062-3762082 1.0000 20 chr10:121632457-12163247 1.0000 20 chr10:104221021-10422104 1.0000 20 chr9:101018142-101018162 1.0000 20 chr16:28223495-28223515 1.0000 20 chr1:16302560-16302580 1.0000 20 chr18:53257143-53257163 1.0000 20 chr15:67834943-67834963 1.0000 20 chr12:27863773-27863793 1.0000 20 chr6:43655494-43655514 1.0000 20 chr1:150336194-150336214 1.0000 20 chr17:27278976-27278996 1.0000 20 chr9:123964139-123964159 1.0000 20 chr22:50312067-50312087 1.0000 20 chr6:37225529-37225549 1.0000 20 chr7:149121-149141 1.0000 20 chr6:33539184-33539204 1.0000 20 chr20:5731000-5731020 1.0000 20 chr7:112758583-112758603 1.0000 20 chr12:110434236-11043425 1.0000 20 chr19:17830315-17830335 1.0000 20 chr18:55297502-55297522 1.0000 20 chr7:74489617-74489637 1.0000 20 chr1:249120314-249120334 1.0000 20 chr2:150444233-150444253 1.0000 20 chr1:202821586-202821606 1.0000 20 chr20:34329563-34329583 1.0000 20 chr7:43909068-43909088 1.0000 20 chr17:74099946-74099966 1.0000 20 chr19:507402-507422 1.0000 20 chr7:113061900-113061920 1.0000 20 chr10:104678285-10467830 1.0000 20 chr16:23160884-23160904 1.0000 20 chr15:56092142-56092162 1.0000 20 chr19:39322515-39322535 1.0000 20 chr12:94071112-94071132 1.0000 20 chr14:69658137-69658157 1.0000 20 chr5:132362197-132362217 1.0000 20 chr19:1269639-1269659 1.0000 20 chr11:73490534-73490554 1.0000 20 chr22:49448270-49448290 1.0000 20 chr6:74363797-74363817 1.0000 20 chr3:128444825-128444845 1.0000 20 chr12:30848888-30848908 1.0000 20 chr12:101673918-10167393 1.0000 20 chrX:30907530-30907550 1.0000 20 chr19:41870225-41870245 1.0000 20 chr6:117923803-117923823 1.0000 20 chr16:30569747-30569767 1.0000 20 chrX:67718807-67718827 1.0000 20 chr8:6264174-6264194 1.0000 20 chr17:72453838-72453858 1.0000 20 chr5:52856484-52856504 1.0000 20 chr2:73441393-73441413 1.0000 20 chr2:74055946-74055966 1.0000 20 chr19:13068008-13068028 1.0000 20 chr6:161412836-161412856 1.0000 20 chr1:155827087-155827107 1.0000 20 chr9:32552322-32552342 1.0000 20 chr10:38265631-38265651 1.0000 20 chr18:57026436-57026456 1.0000 20 chr19:38826414-38826434 1.0000 20 chr5:112043221-112043241 1.0000 20 chr1:113162477-113162497 1.0000 20 chr17:7155249-7155269 1.0000 20 chr3:57741825-57741845 1.0000 20 chr19:1174249-1174269 1.0000 20 chr10:120938259-12093827 1.0000 20 chr19:37663760-37663780 1.0000 20 chr5:79287038-79287058 1.0000 20 chr5:175875402-175875422 1.0000 20 chr9:132565378-132565398 1.0000 20 chr1:161719591-161719611 1.0000 20 chr6:74171497-74171517 1.0000 20 chr1:16161476-16161496 1.0000 20 chr7:133812117-133812137 1.0000 20 chr17:71189147-71189167 1.0000 20 chr1:155189484-155189504 1.0000 20 chr10:123687603-12368762 1.0000 20 chr19:58694714-58694734 1.0000 20 chr8:62008810-62008830 1.0000 20 chr19:39971488-39971508 1.0000 20 chr14:23235815-23235835 1.0000 20 chr2:201728927-201728947 1.0000 20 chr1:52082809-52082829 1.0000 20 chr1:62901895-62901915 1.0000 20 chr9:21813191-21813211 1.0000 20 chr15:40675066-40675086 1.0000 20 chr1:160254907-160254927 1.0000 20 chr11:64052936-64052956 1.0000 20 chr1:155179066-155179086 1.0000 20 chr12:123011269-12301128 1.0000 20 chr11:11863470-11863490 1.0000 20 chr2:33755139-33755159 1.0000 20 chr13:47371267-47371287 1.0000 20 chr14:53173936-53173956 1.0000 20 chr14:55878523-55878543 1.0000 20 chr1:204380936-204380956 1.0000 20 chr1:161102564-161102584 1.0000 20 chr17:40021630-40021650 1.0000 20 chr19:52552130-52552150 1.0000 20 chr1:6685240-6685260 1.0000 20 chr7:42951709-42951729 1.0000 20 chr1:36626690-36626710 1.0000 20 chr19:37701571-37701591 1.0000 20 chr2:70298182-70298202 1.0000 20 chr7:17980087-17980107 1.0000 20 chr1:161087795-161087815 1.0000 20 chr1:1509999-1510019 1.0000 20 chr15:49338738-49338758 1.0000 20 chr19:4670330-4670350 1.0000 20 chr1:107994126-107994146 1.0000 20 chr1:151371953-151371973 1.0000 20 chr5:170814472-170814492 1.0000 20 chr1:2457981-2458001 1.0000 20 chr22:39795796-39795816 1.0000 20 chr7:100861304-100861324 1.0000 20 chr21:34915130-34915150 1.0000 20 chr20:10415810-10415830 1.0000 20 chr8:124286489-124286509 1.0000 20 chr19:47987543-47987563 1.0000 20 chr1:156163735-156163755 1.0000 20 chr18:55289115-55289135 1.0000 20 chr4:17616275-17616295 1.0000 20 chr6:33290875-33290895 1.0000 20 chr1:228270415-228270435 1.0000 20 chr19:59070473-59070493 1.0000 20 chr3:196159239-196159259 1.0000 20 chr6:20534702-20534722 1.0000 20 chr11:65101373-65101393 1.0000 20 chr6:31632771-31632791 1.0000 20 chr3:122102039-122102059 1.0000 20 chr16:2034206-2034226 1.0000 20 chr11:33060946-33060966 1.0000 20 chr2:113342012-113342032 1.0000 20 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/GM12878/inference_raw/MEME/RankLinear0.6_10_YY1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/YY1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 5000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 5000 norand= no csites= 1000 Letter frequencies in dataset: A 0.183 C 0.307 G 0.329 T 0.181 Background letter frequencies (from file dataset with add-one prior applied): A 0.183 C 0.307 G 0.329 T 0.181 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF AAVATGGC MEME-1 width = 8 sites = 39 llr = 369 E-value = 8.2e-056 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAVATGGC MEME-1 Description -------------------------------------------------------------------------------- Simplified A aa4a:::1 pos.-specific C ::3::::9 probability G ::3::aa: matrix T ::::a::: bits 2.5 2.2 ** ** 2.0 ** ** 1.7 ** ** Relative 1.5 ** **** Entropy 1.2 ** ***** (13.7 bits) 1.0 ** ***** 0.7 ** ***** 0.5 ** ***** 0.2 ******** 0.0 -------- Multilevel AAAATGGC consensus C sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVATGGC MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:1509999-1510019 8 6.75e-06 CGCGAAC AAAATGGC GGCCG chr1:204380936-204380956 5 6.75e-06 GCCC AAAATGGC CGCAGGGC chr1:16161476-16161496 13 6.75e-06 GCCGCACCAC AAAATGGC chr5:175875402-175875422 4 6.75e-06 GGC AAAATGGC GGCGCCTGA chr7:113061900-113061920 7 6.75e-06 CTCACT AAAATGGC TGTGTT chr11:67250517-67250537 4 6.75e-06 ACC AAAATGGC GCTAGCTCG chr14:31494856-31494876 9 6.75e-06 TAAAAGCC AAAATGGC TGCC chr7:86782154-86782174 4 6.75e-06 CGG AAAATGGC GGCGGCTTC chr16:30546286-30546306 1 6.75e-06 . AAAATGGC CGTTGCGGCT chr1:46152183-46152203 12 6.75e-06 AGCTCTTCCC AAAATGGC T chr15:79165924-79165944 7 6.75e-06 CGTTGT AAAATGGC CGTTGC chr5:140937536-140937556 12 6.75e-06 CAATCTGTCT AAAATGGC T chr16:2034206-2034226 11 1.81e-05 TTGCGCGGGC AACATGGC GG chr7:100861304-100861324 9 1.81e-05 CCCTATAA AACATGGC GAAA chr1:151371953-151371973 1 1.81e-05 . AACATGGC TGCTGGAAGT chr11:73490534-73490554 3 1.81e-05 TC AACATGGC CGCCAGCGTC chr15:67834943-67834963 8 1.81e-05 CTTTTCC AACATGGC GCCGC chr10:104221021-10422104 3 1.81e-05 CA AACATGGC GGCGGCAGCC chr2:24583383-24583403 2 1.81e-05 C AACATGGC GGCCGCGGCC chr9:133569024-133569044 10 1.81e-05 CCAATTGTA AACATGGC CTC chr16:68877452-68877472 1 1.81e-05 . AACATGGC GGCGGCGGCG chr1:156163735-156163755 1 3.02e-05 . AAGATGGC TACCAGGAGG chr22:39795796-39795816 9 3.02e-05 GTTCCTCC AAGATGGC GGCG chr19:39971488-39971508 3 3.02e-05 GC AAGATGGC GGCCTCGGCA chr7:133812117-133812137 1 3.02e-05 . AAGATGGC GACCTCCGAG chr5:52856484-52856504 6 3.02e-05 GCAGC AAGATGGC GGCGGTG chrX:30907530-30907550 3 3.02e-05 CA AAGATGGC GCCGCCGGGT chr9:123964139-123964159 4 3.02e-05 TCC AAGATGGC GGCGCTCCC chr18:53257143-53257163 3 3.02e-05 CC AAGATGGC GGTGCTGGTC chr6:43445319-43445339 11 3.02e-05 GCCCCGCGGC AAGATGGC GG chr18:23501759-23501779 7 3.42e-05 GAAGGT AAAATGGA CACCCC chr5:32174409-32174429 12 4.09e-05 GCGCCTTTCC AATATGGC G chr13:48575379-48575399 10 5.16e-05 CTGCCGTAG AACATGGA GGC chr17:72453838-72453858 5 6.55e-05 gaac aaatTGGC AGTGCCTG chr12:94071112-94071132 5 9.34e-05 AACA AAGATGGT GTCAACAC chrX:47863470-47863490 10 1.64e-04 CCAATAGTC AACATGGG GCC chr12:123011269-12301128 2 1.90e-04 G AAGAAGGC CGCGGCGCCA chr19:7598952-7598972 3 2.34e-04 TC AGCATGGC GGCCTCAGTC chr7:27200710-27200730 8 2.78e-04 GAGGCGG GAGATGGC GGCGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVATGGC MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:1509999-1510019 6.7e-06 7_[+1]_5 chr1:204380936-204380956 6.7e-06 4_[+1]_8 chr1:16161476-16161496 6.7e-06 12_[+1] chr5:175875402-175875422 6.7e-06 3_[+1]_9 chr7:113061900-113061920 6.7e-06 6_[+1]_6 chr11:67250517-67250537 6.7e-06 3_[+1]_9 chr14:31494856-31494876 6.7e-06 8_[+1]_4 chr7:86782154-86782174 6.7e-06 3_[+1]_9 chr16:30546286-30546306 6.7e-06 [+1]_12 chr1:46152183-46152203 6.7e-06 11_[+1]_1 chr15:79165924-79165944 6.7e-06 6_[+1]_6 chr5:140937536-140937556 6.7e-06 11_[+1]_1 chr16:2034206-2034226 1.8e-05 10_[+1]_2 chr7:100861304-100861324 1.8e-05 8_[+1]_4 chr1:151371953-151371973 1.8e-05 [+1]_12 chr11:73490534-73490554 1.8e-05 2_[+1]_10 chr15:67834943-67834963 1.8e-05 7_[+1]_5 chr10:104221021-10422104 1.8e-05 2_[+1]_10 chr2:24583383-24583403 1.8e-05 1_[+1]_11 chr9:133569024-133569044 1.8e-05 9_[+1]_3 chr16:68877452-68877472 1.8e-05 [+1]_12 chr1:156163735-156163755 3e-05 [+1]_12 chr22:39795796-39795816 3e-05 8_[+1]_4 chr19:39971488-39971508 3e-05 2_[+1]_10 chr7:133812117-133812137 3e-05 [+1]_12 chr5:52856484-52856504 3e-05 5_[+1]_7 chrX:30907530-30907550 3e-05 2_[+1]_10 chr9:123964139-123964159 3e-05 3_[+1]_9 chr18:53257143-53257163 3e-05 2_[+1]_10 chr6:43445319-43445339 3e-05 10_[+1]_2 chr18:23501759-23501779 3.4e-05 6_[+1]_6 chr5:32174409-32174429 4.1e-05 11_[+1]_1 chr13:48575379-48575399 5.2e-05 9_[+1]_3 chr17:72453838-72453858 6.6e-05 4_[+1]_8 chr12:94071112-94071132 9.3e-05 4_[+1]_8 chrX:47863470-47863490 0.00016 9_[+1]_3 chr12:123011269-12301128 0.00019 1_[+1]_11 chr19:7598952-7598972 0.00023 2_[+1]_10 chr7:27200710-27200730 0.00028 7_[+1]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVATGGC MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAVATGGC width=8 seqs=39 chr1:1509999-1510019 ( 8) AAAATGGC 1 chr1:204380936-204380956 ( 5) AAAATGGC 1 chr1:16161476-16161496 ( 13) AAAATGGC 1 chr5:175875402-175875422 ( 4) AAAATGGC 1 chr7:113061900-113061920 ( 7) AAAATGGC 1 chr11:67250517-67250537 ( 4) AAAATGGC 1 chr14:31494856-31494876 ( 9) AAAATGGC 1 chr7:86782154-86782174 ( 4) AAAATGGC 1 chr16:30546286-30546306 ( 1) AAAATGGC 1 chr1:46152183-46152203 ( 12) AAAATGGC 1 chr15:79165924-79165944 ( 7) AAAATGGC 1 chr5:140937536-140937556 ( 12) AAAATGGC 1 chr16:2034206-2034226 ( 11) AACATGGC 1 chr7:100861304-100861324 ( 9) AACATGGC 1 chr1:151371953-151371973 ( 1) AACATGGC 1 chr11:73490534-73490554 ( 3) AACATGGC 1 chr15:67834943-67834963 ( 8) AACATGGC 1 chr10:104221021-10422104 ( 3) AACATGGC 1 chr2:24583383-24583403 ( 2) AACATGGC 1 chr9:133569024-133569044 ( 10) AACATGGC 1 chr16:68877452-68877472 ( 1) AACATGGC 1 chr1:156163735-156163755 ( 1) AAGATGGC 1 chr22:39795796-39795816 ( 9) AAGATGGC 1 chr19:39971488-39971508 ( 3) AAGATGGC 1 chr7:133812117-133812137 ( 1) AAGATGGC 1 chr5:52856484-52856504 ( 6) AAGATGGC 1 chrX:30907530-30907550 ( 3) AAGATGGC 1 chr9:123964139-123964159 ( 4) AAGATGGC 1 chr18:53257143-53257163 ( 3) AAGATGGC 1 chr6:43445319-43445339 ( 11) AAGATGGC 1 chr18:23501759-23501779 ( 7) AAAATGGA 1 chr5:32174409-32174429 ( 12) AATATGGC 1 chr13:48575379-48575399 ( 10) AACATGGA 1 chr17:72453838-72453858 ( 5) AAATTGGC 1 chr12:94071112-94071132 ( 5) AAGATGGT 1 chrX:47863470-47863490 ( 10) AACATGGG 1 chr12:123011269-12301128 ( 2) AAGAAGGC 1 chr19:7598952-7598972 ( 3) AGCATGGC 1 chr7:27200710-27200730 ( 8) GAGATGGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVATGGC MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 7.83209 E= 8.2e-056 241 -1193 -368 -1193 241 -1193 -368 -1193 97 0 -10 -281 241 -1193 -1193 -281 -284 -1193 -1193 243 -1193 -1193 160 -1193 -1193 -1193 160 -1193 -184 155 -368 -281 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVATGGC MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 39 E= 8.2e-056 0.974359 0.000000 0.025641 0.000000 0.974359 0.000000 0.025641 0.000000 0.358974 0.307692 0.307692 0.025641 0.974359 0.000000 0.000000 0.025641 0.025641 0.000000 0.000000 0.974359 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.051282 0.897436 0.025641 0.025641 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAVATGGC MEME-1 regular expression -------------------------------------------------------------------------------- AA[ACG]ATGGC -------------------------------------------------------------------------------- Time 2.47 secs. ******************************************************************************** ******************************************************************************** MOTIF GCCATBTT MEME-2 width = 8 sites = 31 llr = 298 E-value = 2.0e-040 ******************************************************************************** -------------------------------------------------------------------------------- Motif GCCATBTT MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::a::1: pos.-specific C :9a::5:: probability G 9::::3:: matrix T 1:::a39a bits 2.5 ** * 2.2 ** ** 2.0 ** ** 1.7 *** ** Relative 1.5 *** ** Entropy 1.2 ***** ** (13.9 bits) 1.0 ***** ** 0.7 ***** ** 0.5 ***** ** 0.2 ******** 0.0 -------- Multilevel GCCATCTT consensus G sequence T -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCATBTT MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:124286489-124286509 5 1.64e-05 CGCC GCCATCTT GCATTTCA chr2:70298182-70298202 12 1.64e-05 TAAACTTCCA GCCATTTT G chr1:6685240-6685260 3 1.64e-05 CC GCCATCTT TGTTGGGGGC chr2:33755139-33755159 13 1.64e-05 GAGCCCAGCG GCCATTTT chr11:11863470-11863490 6 1.64e-05 CCGCC GCCATTTT TCCATTG chr11:64052936-64052956 10 1.64e-05 ggcccgggg gccATCTT GGC chr1:160254907-160254927 3 1.64e-05 CG GCCATCTT GCTACCTCCG chr19:1174249-1174269 11 1.64e-05 GGTTTCGGGC GCCATCTT GG chr17:74099946-74099966 3 1.64e-05 CG GCCATTTT GAGCGTGGCT chr12:110434236-11043425 11 1.64e-05 CTGCCTTGTC GCCATCTT GA chr16:28223495-28223515 1 1.64e-05 . GCCATCTT GGTAAAGGGA chr4:140216942-140216962 6 1.64e-05 ACGGC GCCATCTT GCGTGGC chr19:1021095-1021115 10 1.64e-05 GCCGCCGCC GCCATCTT CCG chr15:81282119-81282139 9 1.64e-05 TGGAAGCC GCCATTTT CGCT chrX:54556253-54556273 1 1.64e-05 . GCCATTTT CTCACACCCT chr6:117002369-117002389 2 1.64e-05 C GCCATCTT GGATTGCGAA chr19:52511524-52511544 10 1.64e-05 ATGGGGGCC GCCATCTT TGA chr19:4670330-4670350 12 2.75e-05 GCTGGGCGCC GCCATGTT G chr18:55297502-55297522 13 2.75e-05 CGCCGGCGCC GCCATGTT chr1:16302560-16302580 7 2.75e-05 GGCGCC GCCATGTT AGAGTC chr2:234475386-234475406 11 2.75e-05 ACTGGGCGCC GCCATGTT GG chr2:15701420-15701440 4 2.75e-05 GCC GCCATGTT CGCCGAGGA chr7:5553486-5553506 7 2.75e-05 GCGGCC GCCATGTT GAATGT chr9:21813191-21813211 8 4.27e-05 GCTGGCC TCCATCTT AGAGG chr6:117923803-117923823 5 4.27e-05 AGCG GCCATATT AACAACTG chr5:5523404-5523424 11 4.27e-05 aaactgagac tccatttt ga chr7:100435091-100435111 5 6.54e-05 TGAA GCCATCAT AGTCGCCG chr14:55878523-55878543 13 8.64e-05 ACTGGGAGAC GCCATGAT chr1:155827087-155827107 1 1.02e-04 . CCCATTTT AGGGCAGAGT chr5:148929175-148929195 8 1.26e-04 GGAGGAA GACATGTT GGAAC chrX:47880494-47880514 10 1.26e-04 AAGGGAGCA GGCATCTT TAC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCATBTT MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:124286489-124286509 1.6e-05 4_[+2]_8 chr2:70298182-70298202 1.6e-05 11_[+2]_1 chr1:6685240-6685260 1.6e-05 2_[+2]_10 chr2:33755139-33755159 1.6e-05 12_[+2] chr11:11863470-11863490 1.6e-05 5_[+2]_7 chr11:64052936-64052956 1.6e-05 9_[+2]_3 chr1:160254907-160254927 1.6e-05 2_[+2]_10 chr19:1174249-1174269 1.6e-05 10_[+2]_2 chr17:74099946-74099966 1.6e-05 2_[+2]_10 chr12:110434236-11043425 1.6e-05 10_[+2]_2 chr16:28223495-28223515 1.6e-05 [+2]_12 chr4:140216942-140216962 1.6e-05 5_[+2]_7 chr19:1021095-1021115 1.6e-05 9_[+2]_3 chr15:81282119-81282139 1.6e-05 8_[+2]_4 chrX:54556253-54556273 1.6e-05 [+2]_12 chr6:117002369-117002389 1.6e-05 1_[+2]_11 chr19:52511524-52511544 1.6e-05 9_[+2]_3 chr19:4670330-4670350 2.7e-05 11_[+2]_1 chr18:55297502-55297522 2.7e-05 12_[+2] chr1:16302560-16302580 2.7e-05 6_[+2]_6 chr2:234475386-234475406 2.7e-05 10_[+2]_2 chr2:15701420-15701440 2.7e-05 3_[+2]_9 chr7:5553486-5553506 2.7e-05 6_[+2]_6 chr9:21813191-21813211 4.3e-05 7_[+2]_5 chr6:117923803-117923823 4.3e-05 4_[+2]_8 chr5:5523404-5523424 4.3e-05 10_[+2]_2 chr7:100435091-100435111 6.5e-05 4_[+2]_8 chr14:55878523-55878543 8.6e-05 12_[+2] chr1:155827087-155827107 0.0001 [+2]_12 chr5:148929175-148929195 0.00013 7_[+2]_5 chrX:47880494-47880514 0.00013 9_[+2]_3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCATBTT MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GCCATBTT width=8 seqs=31 chr8:124286489-124286509 ( 5) GCCATCTT 1 chr2:70298182-70298202 ( 12) GCCATTTT 1 chr1:6685240-6685260 ( 3) GCCATCTT 1 chr2:33755139-33755159 ( 13) GCCATTTT 1 chr11:11863470-11863490 ( 6) GCCATTTT 1 chr11:64052936-64052956 ( 10) GCCATCTT 1 chr1:160254907-160254927 ( 3) GCCATCTT 1 chr19:1174249-1174269 ( 11) GCCATCTT 1 chr17:74099946-74099966 ( 3) GCCATTTT 1 chr12:110434236-11043425 ( 11) GCCATCTT 1 chr16:28223495-28223515 ( 1) GCCATCTT 1 chr4:140216942-140216962 ( 6) GCCATCTT 1 chr19:1021095-1021115 ( 10) GCCATCTT 1 chr15:81282119-81282139 ( 9) GCCATTTT 1 chrX:54556253-54556273 ( 1) GCCATTTT 1 chr6:117002369-117002389 ( 2) GCCATCTT 1 chr19:52511524-52511544 ( 10) GCCATCTT 1 chr19:4670330-4670350 ( 12) GCCATGTT 1 chr18:55297502-55297522 ( 13) GCCATGTT 1 chr1:16302560-16302580 ( 7) GCCATGTT 1 chr2:234475386-234475406 ( 11) GCCATGTT 1 chr2:15701420-15701440 ( 4) GCCATGTT 1 chr7:5553486-5553506 ( 7) GCCATGTT 1 chr9:21813191-21813211 ( 8) TCCATCTT 1 chr6:117923803-117923823 ( 5) GCCATATT 1 chr5:5523404-5523424 ( 11) TCCATTTT 1 chr7:100435091-100435111 ( 5) GCCATCAT 1 chr14:55878523-55878543 ( 13) GCCATGAT 1 chr1:155827087-155827107 ( 1) CCCATTTT 1 chr5:148929175-148929195 ( 8) GACATGTT 1 chrX:47880494-47880514 ( 10) GGCATCTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCATBTT MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.42938 E= 2.0e-040 -1160 -325 146 -148 -251 161 -335 -1160 -1160 170 -1160 -1160 245 -1160 -1160 -1160 -1160 -1160 -1160 247 -251 56 -35 51 -151 -1160 -1160 237 -1160 -1160 -1160 247 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCATBTT MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 31 E= 2.0e-040 0.000000 0.032258 0.903226 0.064516 0.032258 0.935484 0.032258 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.032258 0.451613 0.258065 0.258065 0.064516 0.000000 0.000000 0.935484 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCATBTT MEME-2 regular expression -------------------------------------------------------------------------------- GCCAT[CGT]TT -------------------------------------------------------------------------------- Time 3.19 secs. ******************************************************************************** ******************************************************************************** MOTIF ATGGCGGC MEME-3 width = 8 sites = 15 llr = 130 E-value = 9.3e-003 ******************************************************************************** -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-3 Description -------------------------------------------------------------------------------- Simplified A a::::::2 pos.-specific C :1::9118 probability G ::aa199: matrix T :9:::::: bits 2.5 * 2.2 * 2.0 ** 1.7 ** Relative 1.5 **** Entropy 1.2 ******** (12.5 bits) 1.0 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel ATGGCGGC consensus A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:17616275-17616295 3 3.66e-05 AC ATGGCGGC TCCACTAGGG chr2:73441393-73441413 2 3.66e-05 G ATGGCGGC CTCCATGTGC chr12:27863773-27863793 4 3.66e-05 GCC ATGGCGGC CGCCGCGCT chr2:105654550-105654570 1 3.66e-05 . ATGGCGGC GCCCTGTGTG chr11:45376959-45376979 2 3.66e-05 C ATGGCGGC TTCCTGGACC chr11:74459925-74459945 1 3.66e-05 . ATGGCGGC TGCAGGTCCG chr9:115819009-115819029 3 3.66e-05 CG ATGGCGGC GCCCTTCGGT chr14:53173936-53173956 2 5.84e-05 C ATGGCGGA CCCTAGAGAT chr17:71189147-71189167 1 5.84e-05 . ATGGCGGA GGGGGCGGGA chr5:112043221-112043241 2 5.84e-05 G ATGGCGGA GGGCAAGTAG chr19:52511524-52511544 1 9.76e-05 . ATGGGGGC CGCCATCTTT chr19:52552622-52552642 8 9.76e-05 GAGCATC ATGGGGGC GGCCA chr21:34915130-34915150 3 1.66e-04 TA ATGGCGCC TGCGTCAGAC chr1:36626690-36626710 2 1.66e-04 A ATGGCCGC CAGCCGGGCC chr5:115420723-115420743 1 2.51e-04 . ACGGCGGC AGTGCGAGAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:17616275-17616295 3.7e-05 2_[+3]_10 chr2:73441393-73441413 3.7e-05 1_[+3]_11 chr12:27863773-27863793 3.7e-05 3_[+3]_9 chr2:105654550-105654570 3.7e-05 [+3]_12 chr11:45376959-45376979 3.7e-05 1_[+3]_11 chr11:74459925-74459945 3.7e-05 [+3]_12 chr9:115819009-115819029 3.7e-05 2_[+3]_10 chr14:53173936-53173956 5.8e-05 1_[+3]_11 chr17:71189147-71189167 5.8e-05 [+3]_12 chr5:112043221-112043241 5.8e-05 1_[+3]_11 chr19:52511524-52511544 9.8e-05 [+3]_12 chr19:52552622-52552642 9.8e-05 7_[+3]_5 chr21:34915130-34915150 0.00017 2_[+3]_10 chr1:36626690-36626710 0.00017 1_[+3]_11 chr5:115420723-115420743 0.00025 [+3]_12 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ATGGCGGC width=8 seqs=15 chr4:17616275-17616295 ( 3) ATGGCGGC 1 chr2:73441393-73441413 ( 2) ATGGCGGC 1 chr12:27863773-27863793 ( 4) ATGGCGGC 1 chr2:105654550-105654570 ( 1) ATGGCGGC 1 chr11:45376959-45376979 ( 2) ATGGCGGC 1 chr11:74459925-74459945 ( 1) ATGGCGGC 1 chr9:115819009-115819029 ( 3) ATGGCGGC 1 chr14:53173936-53173956 ( 2) ATGGCGGA 1 chr17:71189147-71189167 ( 1) ATGGCGGA 1 chr5:112043221-112043241 ( 2) ATGGCGGA 1 chr19:52511524-52511544 ( 1) ATGGGGGC 1 chr19:52552622-52552642 ( 8) ATGGGGGC 1 chr21:34915130-34915150 ( 3) ATGGCGCC 1 chr1:36626690-36626710 ( 2) ATGGCCGC 1 chr5:115420723-115420743 ( 1) ACGGCGGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.42938 E= 9.3e-003 245 -1055 -1055 -1055 -1055 -220 -1055 237 -1055 -1055 160 -1055 -1055 -1055 160 -1055 -1055 150 -130 -1055 -1055 -220 150 -1055 -1055 -220 150 -1055 12 138 -1055 -1055 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 15 E= 9.3e-003 1.000000 0.000000 0.000000 0.000000 0.000000 0.066667 0.000000 0.933333 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.866667 0.133333 0.000000 0.000000 0.066667 0.933333 0.000000 0.000000 0.066667 0.933333 0.000000 0.200000 0.800000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATGGCGGC MEME-3 regular expression -------------------------------------------------------------------------------- ATGGCGG[CA] -------------------------------------------------------------------------------- Time 3.93 secs. ******************************************************************************** ******************************************************************************** MOTIF CGCCGCCA MEME-4 width = 8 sites = 12 llr = 102 E-value = 7.4e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif CGCCGCCA MEME-4 Description -------------------------------------------------------------------------------- Simplified A :31::::a pos.-specific C a:8a:aa: probability G :72:a::: matrix T :1:::::: bits 2.5 * 2.2 * 2.0 * 1.7 * * *** Relative 1.5 * ***** Entropy 1.2 * ***** (12.3 bits) 1.0 * ***** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CGCCGCCA consensus A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGCCGCCA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:17980087-17980107 11 5.40e-05 GCGACGGACG CGCCGCCA TC chr19:13068008-13068028 10 5.40e-05 TCGCACGGA CGCCGCCA TCT chr15:41836424-41836444 13 5.40e-05 CCTGTCTGGG CGCCGCCA chrX:47180910-47180930 10 5.40e-05 TTCCTCGGG CGCCGCCA TGT chr4:147443091-147443111 1 5.40e-05 . CGCCGCCA TCACTACCAC chr17:74732631-74732651 6 5.40e-05 TATCT CGCCGCCA GACGCCA chr3:122102039-122102059 11 8.41e-05 TCACAGTTCA CACCGCCA CT chr2:128459108-128459128 7 8.41e-05 GACCTC CACCGCCA GCTGCA chr1:161087795-161087815 13 1.14e-04 GACCGCTGTT CTCCGCCA chr12:123011269-12301128 12 1.72e-04 AAGAAGGCCG CGGCGCCA T chr22:38902851-38902871 12 1.72e-04 CGGCGGGCCC CGGCGCCA T chr10:99393292-99393312 13 2.54e-04 CAACCGGGAG CAACGCCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGCCGCCA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:17980087-17980107 5.4e-05 10_[+4]_2 chr19:13068008-13068028 5.4e-05 9_[+4]_3 chr15:41836424-41836444 5.4e-05 12_[+4] chrX:47180910-47180930 5.4e-05 9_[+4]_3 chr4:147443091-147443111 5.4e-05 [+4]_12 chr17:74732631-74732651 5.4e-05 5_[+4]_7 chr3:122102039-122102059 8.4e-05 10_[+4]_2 chr2:128459108-128459128 8.4e-05 6_[+4]_6 chr1:161087795-161087815 0.00011 12_[+4] chr12:123011269-12301128 0.00017 11_[+4]_1 chr22:38902851-38902871 0.00017 11_[+4]_1 chr10:99393292-99393312 0.00025 12_[+4] -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGCCGCCA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CGCCGCCA width=8 seqs=12 chr7:17980087-17980107 ( 11) CGCCGCCA 1 chr19:13068008-13068028 ( 10) CGCCGCCA 1 chr15:41836424-41836444 ( 13) CGCCGCCA 1 chrX:47180910-47180930 ( 10) CGCCGCCA 1 chr4:147443091-147443111 ( 1) CGCCGCCA 1 chr17:74732631-74732651 ( 6) CGCCGCCA 1 chr3:122102039-122102059 ( 11) CACCGCCA 1 chr2:128459108-128459128 ( 7) CACCGCCA 1 chr1:161087795-161087815 ( 13) CTCCGCCA 1 chr12:123011269-12301128 ( 12) CGGCGCCA 1 chr22:38902851-38902871 ( 12) CGGCGCCA 1 chr10:99393292-99393312 ( 13) CAACGCCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGCCGCCA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.52481 E= 7.4e+001 -1023 170 -1023 -1023 45 -1023 102 -111 -114 129 -98 -1023 -1023 170 -1023 -1023 -1023 -1023 160 -1023 -1023 170 -1023 -1023 -1023 170 -1023 -1023 245 -1023 -1023 -1023 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGCCGCCA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 12 E= 7.4e+001 0.000000 1.000000 0.000000 0.000000 0.250000 0.000000 0.666667 0.083333 0.083333 0.750000 0.166667 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CGCCGCCA MEME-4 regular expression -------------------------------------------------------------------------------- C[GA]CCGCCA -------------------------------------------------------------------------------- Time 4.65 secs. ******************************************************************************** ******************************************************************************** MOTIF TCTAATCA MEME-5 width = 8 sites = 2 llr = 25 E-value = 9.4e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCTAATCA MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::aa::a pos.-specific C :a::::a: probability G :::::::: matrix T a:a::a:: bits 2.5 * **** * 2.2 * **** * 2.0 * **** * 1.7 ******** Relative 1.5 ******** Entropy 1.2 ******** (18.2 bits) 1.0 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TCTAATCA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTAATCA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:31632771-31632791 9 3.43e-06 GGCGCCAT TCTAATCA GAAG chr14:23206502-23206522 1 3.43e-06 . tctaatca tgcctccagg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTAATCA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:31632771-31632791 3.4e-06 8_[+5]_4 chr14:23206502-23206522 3.4e-06 [+5]_12 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTAATCA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCTAATCA width=8 seqs=2 chr6:31632771-31632791 ( 9) TCTAATCA 1 chr14:23206502-23206522 ( 1) TCTAATCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTAATCA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 10.6653 E= 9.4e+002 -765 -765 -765 246 -765 170 -765 -765 -765 -765 -765 246 244 -765 -765 -765 244 -765 -765 -765 -765 -765 -765 246 -765 170 -765 -765 244 -765 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTAATCA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 9.4e+002 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCTAATCA MEME-5 regular expression -------------------------------------------------------------------------------- TCTAATCA -------------------------------------------------------------------------------- Time 5.45 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:31456893-31456913 8.85e-01 20 chr2:62733050-62733070 2.03e-01 20 chr18:23501759-23501779 1.24e-02 6_[+1(3.42e-05)]_6 chr1:161147243-161147263 7.76e-01 20 chr9:115819009-115819029 1.23e-02 2_[+3(3.66e-05)]_10 chr16:1020935-1020955 6.66e-01 20 chr20:35374635-35374655 4.46e-01 20 chr8:120886001-120886021 8.33e-01 20 chr19:52552622-52552642 6.74e-04 7_[+3(9.76e-05)]_5 chr1:223886100-223886120 8.55e-02 20 chr6:112350589-112350609 9.58e-02 20 chr5:139682640-139682660 1.06e-01 20 chr7:27200710-27200730 2.08e-03 10_[+3(3.66e-05)]_2 chr19:7598952-7598972 4.63e-04 5_[+3(3.66e-05)]_7 chrX:152127518-152127538 5.14e-01 20 chr19:19600120-19600140 9.58e-01 20 chr17:74732631-74732651 4.06e-02 5_[+4(5.40e-05)]_7 chr5:5523404-5523424 1.75e-02 10_[+2(4.27e-05)]_2 chr18:54318410-54318430 8.75e-01 20 chr1:35657757-35657777 5.15e-01 20 chr19:52408326-52408346 4.19e-01 20 chr17:4270110-4270130 9.57e-01 20 chrX:47880494-47880514 2.31e-02 20 chr12:72058031-72058051 5.08e-01 20 chr5:134073591-134073611 5.07e-01 20 chr5:140937536-140937556 5.04e-03 11_[+1(6.75e-06)]_1 chr6:37467770-37467790 4.82e-01 20 chrX:47225800-47225820 7.50e-01 20 chr2:232316893-232316913 4.22e-01 20 chr6:29617595-29617615 6.92e-01 20 chr4:147443091-147443111 8.04e-03 [+4(5.40e-05)]_12 chr1:78245253-78245273 8.61e-01 20 chr12:14538216-14538236 8.93e-01 20 chr5:134209989-134210009 1.85e-01 20 chr15:79165924-79165944 9.83e-04 6_[+1(6.75e-06)]_6 chr7:100435091-100435111 1.19e-02 4_[+2(6.54e-05)]_8 chr11:64015013-64015033 6.68e-01 20 chr20:45980523-45980543 7.42e-01 20 chr19:52511524-52511544 1.56e-05 [+3(9.76e-05)]_1_[+2(1.64e-05)]_3 chrX:47180910-47180930 2.13e-02 9_[+4(5.40e-05)]_3 chr19:984365-984385 2.58e-01 20 chr12:32908778-32908798 4.49e-02 20 chr5:148929175-148929195 1.81e-02 20 chr6:117002369-117002389 3.55e-03 1_[+2(1.64e-05)]_11 chr1:161129282-161129302 9.76e-01 20 chr7:128911765-128911785 1.84e-02 20 chrX:54556253-54556273 1.12e-02 [+2(1.64e-05)]_12 chr17:16118841-16118861 4.67e-01 20 chr7:106239400-106239420 2.13e-01 20 chr8:145515311-145515331 9.88e-01 20 chr1:46152183-46152203 1.72e-03 11_[+1(6.75e-06)]_1 chr19:49127403-49127423 4.48e-02 20 chr22:38902851-38902871 5.65e-02 20 chrX:63615397-63615417 3.06e-01 20 chrX:48455870-48455890 6.67e-01 20 chr15:93461261-93461281 5.71e-01 20 chr16:30546286-30546306 1.92e-03 [+1(6.75e-06)]_12 chr12:15743471-15743491 6.07e-01 20 chr19:12886484-12886504 6.84e-01 20 chr17:3572121-3572141 2.28e-01 20 chr5:32174409-32174429 3.06e-03 11_[+1(4.09e-05)]_1 chr1:75198863-75198883 7.33e-01 20 chr7:99686595-99686615 7.87e-01 20 chrX:47696132-47696152 9.98e-01 20 chr18:2571293-2571313 9.04e-01 20 chr2:128459108-128459128 5.31e-02 6_[+4(8.41e-05)]_6 chr10:99393292-99393312 8.11e-02 20 chr2:86426615-86426635 8.87e-01 20 chr2:27357641-27357661 1.85e-01 20 chr16:68877452-68877472 1.37e-04 [+1(1.81e-05)]_12 chr9:133569024-133569044 5.96e-05 9_[+1(1.81e-05)]_3 chr14:23206502-23206522 3.71e-04 [+5(3.43e-06)]_12 chr16:30773662-30773682 9.19e-01 20 chr17:42767094-42767114 1.12e-01 20 chr1:99646051-99646071 8.23e-01 20 chr11:10879342-10879362 4.15e-01 20 chr7:86782154-86782174 2.36e-05 3_[+1(6.75e-06)]_9 chr6:43445319-43445339 2.47e-03 10_[+1(3.02e-05)]_2 chr14:31494856-31494876 6.34e-05 8_[+1(6.75e-06)]_4 chrX:24168516-24168536 9.46e-01 20 chr10:71267767-71267787 6.83e-01 20 chr19:50321393-50321413 7.94e-01 20 chr2:183989050-183989070 1.31e-02 20 chr3:185655220-185655240 4.88e-01 20 chr2:24583383-24583403 7.93e-05 1_[+1(1.81e-05)]_11 chr11:74459925-74459945 2.64e-02 [+3(3.66e-05)]_12 chr5:134074121-134074141 7.88e-01 20 chr11:67250517-67250537 5.74e-04 3_[+1(6.75e-06)]_9 chr9:131965214-131965234 2.27e-01 20 chr11:34938220-34938240 4.04e-01 20 chr19:41945769-41945789 7.81e-01 20 chr15:41836424-41836444 1.08e-02 12_[+4(5.40e-05)] chr22:38578017-38578037 1.55e-01 20 chr11:45376959-45376979 4.56e-02 1_[+3(3.66e-05)]_11 chr12:122492393-12249241 1.67e-01 20 chr7:5553486-5553506 2.87e-04 6_[+2(2.75e-05)]_6 chr15:81282119-81282139 7.13e-04 8_[+2(1.64e-05)]_4 chr5:176981628-176981648 6.62e-01 20 chr7:152456705-152456725 3.58e-01 20 chr2:105654550-105654570 4.87e-03 [+3(3.66e-05)]_12 chr5:115420723-115420743 3.42e-02 20 chr19:10426645-10426665 2.06e-01 20 chr13:48575379-48575399 5.46e-03 9_[+1(5.16e-05)]_3 chr7:25932633-25932653 6.04e-01 20 chrX:47342091-47342111 5.76e-01 20 chrX:152110225-152110245 3.33e-01 20 chrX:47863470-47863490 5.28e-04 20 chr19:1021095-1021115 3.14e-04 9_[+2(1.64e-05)]_3 chr20:48552963-48552983 9.72e-01 20 chr10:104192378-10419239 9.14e-01 20 chr4:140216942-140216962 1.67e-05 5_[+2(1.64e-05)]_7 chr19:2270762-2270782 2.14e-01 20 chr5:140699957-140699977 8.24e-01 20 chr2:15701420-15701440 2.07e-02 3_[+2(2.75e-05)]_9 chr2:234475386-234475406 8.57e-05 10_[+2(2.75e-05)]_2 chr20:3762062-3762082 5.11e-01 20 chr10:121632457-12163247 3.60e-01 20 chr10:104221021-10422104 2.40e-05 2_[+1(1.81e-05)]_10 chr9:101018142-101018162 9.05e-01 20 chr16:28223495-28223515 4.78e-03 [+2(1.64e-05)]_12 chr1:16302560-16302580 2.60e-04 6_[+2(2.75e-05)]_6 chr18:53257143-53257163 4.37e-03 2_[+1(3.02e-05)]_10 chr15:67834943-67834963 2.61e-05 7_[+1(1.81e-05)]_5 chr12:27863773-27863793 1.92e-03 3_[+3(3.66e-05)]_9 chr6:43655494-43655514 3.13e-01 20 chr1:150336194-150336214 9.23e-01 20 chr17:27278976-27278996 6.12e-01 20 chr9:123964139-123964159 1.25e-05 3_[+1(3.02e-05)]_9 chr22:50312067-50312087 3.91e-01 20 chr6:37225529-37225549 9.55e-01 20 chr7:149121-149141 9.88e-01 20 chr6:33539184-33539204 4.82e-01 20 chr20:5731000-5731020 3.51e-01 20 chr7:112758583-112758603 2.90e-02 20 chr12:110434236-11043425 3.37e-03 10_[+2(1.64e-05)]_2 chr19:17830315-17830335 7.27e-01 20 chr18:55297502-55297522 5.49e-05 12_[+2(2.75e-05)] chr7:74489617-74489637 6.64e-01 20 chr1:249120314-249120334 4.97e-01 20 chr2:150444233-150444253 1.88e-01 20 chr1:202821586-202821606 4.76e-01 20 chr20:34329563-34329583 3.66e-01 20 chr7:43909068-43909088 4.53e-01 20 chr17:74099946-74099966 7.00e-03 2_[+2(1.64e-05)]_10 chr19:507402-507422 5.89e-01 20 chr7:113061900-113061920 1.06e-03 6_[+1(6.75e-06)]_6 chr10:104678285-10467830 8.17e-01 20 chr16:23160884-23160904 5.47e-01 20 chr15:56092142-56092162 6.43e-01 20 chr19:39322515-39322535 1.24e-01 20 chr12:94071112-94071132 1.05e-02 4_[+1(9.34e-05)]_8 chr14:69658137-69658157 9.32e-01 20 chr5:132362197-132362217 6.96e-01 20 chr19:1269639-1269659 9.41e-01 20 chr11:73490534-73490554 7.39e-06 2_[+1(1.81e-05)]_10 chr22:49448270-49448290 7.70e-01 20 chr6:74363797-74363817 5.67e-01 20 chr3:128444825-128444845 6.23e-01 20 chr12:30848888-30848908 3.68e-01 20 chr12:101673918-10167393 9.44e-01 20 chrX:30907530-30907550 8.98e-05 2_[+1(3.02e-05)]_10 chr19:41870225-41870245 4.31e-01 20 chr6:117923803-117923823 3.67e-03 4_[+2(4.27e-05)]_8 chr16:30569747-30569767 9.67e-01 20 chrX:67718807-67718827 2.48e-01 20 chr8:6264174-6264194 9.97e-02 20 chr17:72453838-72453858 2.41e-02 4_[+1(6.55e-05)]_8 chr5:52856484-52856504 2.53e-04 5_[+1(3.02e-05)]_7 chr2:73441393-73441413 1.70e-03 1_[+3(3.66e-05)]_11 chr2:74055946-74055966 7.44e-01 20 chr19:13068008-13068028 1.15e-02 9_[+4(5.40e-05)]_3 chr6:161412836-161412856 5.84e-01 20 chr1:155827087-155827107 6.02e-02 20 chr9:32552322-32552342 8.10e-01 20 chr10:38265631-38265651 3.06e-01 20 chr18:57026436-57026456 8.73e-01 20 chr19:38826414-38826434 4.47e-01 20 chr5:112043221-112043241 3.94e-02 1_[+3(5.84e-05)]_11 chr1:113162477-113162497 7.90e-01 20 chr17:7155249-7155269 9.45e-01 20 chr3:57741825-57741845 7.38e-01 20 chr19:1174249-1174269 1.93e-03 10_[+2(1.64e-05)]_2 chr10:120938259-12093827 7.90e-01 20 chr19:37663760-37663780 2.40e-01 20 chr5:79287038-79287058 2.82e-01 20 chr5:175875402-175875422 1.92e-06 3_[+1(6.75e-06)]_9 chr9:132565378-132565398 8.76e-01 20 chr1:161719591-161719611 5.92e-01 20 chr6:74171497-74171517 3.49e-01 20 chr1:16161476-16161496 1.95e-03 12_[+1(6.75e-06)] chr7:133812117-133812137 1.83e-03 [+1(3.02e-05)]_12 chr17:71189147-71189167 9.03e-02 [+3(5.84e-05)]_12 chr1:155189484-155189504 4.68e-01 20 chr10:123687603-12368762 9.47e-02 20 chr19:58694714-58694734 4.08e-01 20 chr8:62008810-62008830 3.52e-01 20 chr19:39971488-39971508 1.50e-04 2_[+1(3.02e-05)]_10 chr14:23235815-23235835 9.91e-02 20 chr2:201728927-201728947 5.73e-01 20 chr1:52082809-52082829 1.71e-01 20 chr1:62901895-62901915 7.26e-01 20 chr9:21813191-21813211 6.37e-03 7_[+2(4.27e-05)]_5 chr15:40675066-40675086 7.27e-01 20 chr1:160254907-160254927 2.55e-02 2_[+2(1.64e-05)]_10 chr11:64052936-64052956 9.03e-04 9_[+2(1.64e-05)]_3 chr1:155179066-155179086 6.47e-01 20 chr12:123011269-12301128 4.56e-04 20 chr11:11863470-11863490 1.79e-04 5_[+2(1.64e-05)]_7 chr2:33755139-33755159 9.56e-03 12_[+2(1.64e-05)] chr13:47371267-47371287 2.76e-01 20 chr14:53173936-53173956 7.70e-02 1_[+3(5.84e-05)]_11 chr14:55878523-55878543 7.84e-03 12_[+2(8.64e-05)] chr1:204380936-204380956 4.74e-05 4_[+1(6.75e-06)]_8 chr1:161102564-161102584 9.14e-02 20 chr17:40021630-40021650 7.13e-01 20 chr19:52552130-52552150 5.50e-01 20 chr1:6685240-6685260 3.72e-03 2_[+2(1.64e-05)]_10 chr7:42951709-42951729 5.74e-01 20 chr1:36626690-36626710 9.88e-03 20 chr19:37701571-37701591 5.70e-01 20 chr2:70298182-70298202 8.83e-03 11_[+2(1.64e-05)]_1 chr7:17980087-17980107 1.17e-02 10_[+4(5.40e-05)]_2 chr1:161087795-161087815 5.43e-02 20 chr1:1509999-1510019 3.16e-05 7_[+1(6.75e-06)]_5 chr15:49338738-49338758 5.01e-01 20 chr19:4670330-4670350 8.57e-05 11_[+2(2.75e-05)]_1 chr1:107994126-107994146 1.20e-01 20 chr1:151371953-151371973 3.51e-03 [+1(1.81e-05)]_12 chr5:170814472-170814492 3.00e-01 20 chr1:2457981-2458001 9.11e-01 20 chr22:39795796-39795816 8.37e-06 8_[+1(3.02e-05)]_4 chr7:100861304-100861324 8.67e-04 8_[+1(1.81e-05)]_4 chr21:34915130-34915150 3.51e-02 20 chr20:10415810-10415830 7.39e-01 20 chr8:124286489-124286509 1.97e-04 4_[+2(1.64e-05)]_8 chr19:47987543-47987563 4.69e-01 20 chr1:156163735-156163755 1.60e-02 [+1(3.02e-05)]_12 chr18:55289115-55289135 6.07e-01 20 chr4:17616275-17616295 1.58e-03 2_[+3(3.66e-05)]_10 chr6:33290875-33290895 1.18e-01 20 chr1:228270415-228270435 8.52e-01 20 chr19:59070473-59070493 4.84e-01 20 chr3:196159239-196159259 7.07e-01 20 chr6:20534702-20534722 7.02e-02 20 chr11:65101373-65101393 2.47e-01 20 chr6:31632771-31632791 6.67e-04 8_[+5(3.43e-06)]_4 chr3:122102039-122102059 5.83e-02 10_[+4(8.41e-05)]_2 chr16:2034206-2034226 1.91e-03 10_[+1(1.81e-05)]_2 chr11:33060946-33060966 2.74e-01 20 chr2:113342012-113342032 1.48e-01 20 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n05.farnam.hpc.yale.internal ********************************************************************************