******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/STAT5A.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr11:1937605-1937625 1.0000 20 chr11:1915028-1915048 1.0000 20 chr8:142118403-142118423 1.0000 20 chr11:111229078-11122909 1.0000 20 chr19:4815176-4815196 1.0000 20 chr1:207097266-207097286 1.0000 20 chr4:881221-881241 1.0000 20 chr22:39157950-39157970 1.0000 20 chr14:106171987-10617200 1.0000 20 chr6:11319752-11319772 1.0000 20 chr17:65050972-65050992 1.0000 20 chr17:8732680-8732700 1.0000 20 chr20:36034888-36034908 1.0000 20 chr8:11418285-11418305 1.0000 20 chr19:1389190-1389210 1.0000 20 chr19:3831029-3831049 1.0000 20 chr22:37704837-37704857 1.0000 20 chr1:15762040-15762060 1.0000 20 chr19:40170960-40170980 1.0000 20 chr16:28100870-28100890 1.0000 20 chr12:6927042-6927062 1.0000 20 chr18:60988174-60988194 1.0000 20 chr3:127406237-127406257 1.0000 20 chr12:124963847-12496386 1.0000 20 chr21:45668508-45668528 1.0000 20 chr20:44973337-44973357 1.0000 20 chr13:111526463-11152648 1.0000 20 chr21:26935399-26935419 1.0000 20 chr9:34652544-34652564 1.0000 20 chr17:74273747-74273767 1.0000 20 chr9:138542388-138542408 1.0000 20 chr18:46546117-46546137 1.0000 20 chr17:62224368-62224388 1.0000 20 chr21:26952616-26952636 1.0000 20 chr9:137171148-137171168 1.0000 20 chr2:121035424-121035444 1.0000 20 chr1:6093418-6093438 1.0000 20 chr6:296611-296631 1.0000 20 chr19:6532625-6532645 1.0000 20 chr8:93284911-93284931 1.0000 20 chr6:412344-412364 1.0000 20 chr4:185393799-185393819 1.0000 20 chr7:24795441-24795461 1.0000 20 chr11:47379751-47379771 1.0000 20 chr1:207097467-207097487 1.0000 20 chr9:92714900-92714920 1.0000 20 chr7:154997868-154997888 1.0000 20 chr15:57252459-57252479 1.0000 20 chr16:89980943-89980963 1.0000 20 chr1:31342101-31342121 1.0000 20 chr2:201997451-201997471 1.0000 20 chr17:8732880-8732900 1.0000 20 chr9:130628278-130628298 1.0000 20 chr3:16549138-16549158 1.0000 20 chr10:135162745-13516276 1.0000 20 chr17:78264214-78264234 1.0000 20 chr21:26950799-26950819 1.0000 20 chr15:101326465-10132648 1.0000 20 chr21:46324556-46324576 1.0000 20 chr22:23244158-23244178 1.0000 20 chr17:62077126-62077146 1.0000 20 chr6:26056132-26056152 1.0000 20 chr6:167061564-167061584 1.0000 20 chr11:497456-497476 1.0000 20 chr8:29949278-29949298 1.0000 20 chr1:183811811-183811831 1.0000 20 chr20:33153690-33153710 1.0000 20 chr20:61168322-61168342 1.0000 20 chr7:97762704-97762724 1.0000 20 chr1:67637744-67637764 1.0000 20 chr2:88315876-88315896 1.0000 20 chr1:226920880-226920900 1.0000 20 chr7:124533382-124533402 1.0000 20 chr11:65197563-65197583 1.0000 20 chr2:68666188-68666208 1.0000 20 chr21:26952964-26952984 1.0000 20 chr3:188027671-188027691 1.0000 20 chr8:11418495-11418515 1.0000 20 chr6:137605364-137605384 1.0000 20 chr7:148610412-148610432 1.0000 20 chr1:117087610-117087630 1.0000 20 chr13:111526665-11152668 1.0000 20 chr8:142046316-142046336 1.0000 20 chr2:191827073-191827093 1.0000 20 chr8:144636747-144636767 1.0000 20 chr1:83974292-83974312 1.0000 20 chr17:27052525-27052545 1.0000 20 chr2:100752945-100752965 1.0000 20 chr22:46075372-46075392 1.0000 20 chr1:226837142-226837162 1.0000 20 chrX:47489658-47489678 1.0000 20 chr3:119269510-119269530 1.0000 20 chr1:160139600-160139620 1.0000 20 chr6:45888726-45888746 1.0000 20 chr10:4174075-4174095 1.0000 20 chr6:26031926-26031946 1.0000 20 chr8:56901987-56902007 1.0000 20 chr19:2557161-2557181 1.0000 20 chr18:51675553-51675573 1.0000 20 chr6:26045980-26046000 1.0000 20 chr10:65467265-65467285 1.0000 20 chr5:95261827-95261847 1.0000 20 chr2:240212401-240212421 1.0000 20 chr20:40091221-40091241 1.0000 20 chr11:111229288-11122930 1.0000 20 chr14:71990931-71990951 1.0000 20 chr12:104882447-10488246 1.0000 20 chr9:136780826-136780846 1.0000 20 chr13:114268219-11426823 1.0000 20 chr5:403156-403176 1.0000 20 chr14:68730426-68730446 1.0000 20 chr6:42307904-42307924 1.0000 20 chr17:8804161-8804181 1.0000 20 chr18:21589809-21589829 1.0000 20 chr4:104419623-104419643 1.0000 20 chr1:174784703-174784723 1.0000 20 chr19:2336636-2336656 1.0000 20 chr8:60964352-60964372 1.0000 20 chr16:84999651-84999671 1.0000 20 chr1:247569673-247569693 1.0000 20 chr1:89506938-89506958 1.0000 20 chr1:29289130-29289150 1.0000 20 chr13:50819291-50819311 1.0000 20 chr9:119714254-119714274 1.0000 20 chr1:79506549-79506569 1.0000 20 chr3:71133109-71133129 1.0000 20 chr4:71544253-71544273 1.0000 20 chr16:2011043-2011063 1.0000 20 chr1:207097667-207097687 1.0000 20 chr1:150540000-150540020 1.0000 20 chr16:75413427-75413447 1.0000 20 chr21:26951001-26951021 1.0000 20 chr2:100864218-100864238 1.0000 20 chr6:132006695-132006715 1.0000 20 chr21:45378396-45378416 1.0000 20 chr14:69533647-69533667 1.0000 20 chr1:209943968-209943988 1.0000 20 chr2:142271594-142271614 1.0000 20 chr12:95482325-95482345 1.0000 20 chr1:66865733-66865753 1.0000 20 chr5:95616025-95616045 1.0000 20 chr8:146012811-146012831 1.0000 20 chr5:33985475-33985495 1.0000 20 chr4:76979664-76979684 1.0000 20 chr2:181993090-181993110 1.0000 20 chr19:7197834-7197854 1.0000 20 chr6:74224303-74224323 1.0000 20 chr8:60027887-60027907 1.0000 20 chr21:35956597-35956617 1.0000 20 chr13:24368920-24368940 1.0000 20 chr7:42909154-42909174 1.0000 20 chr3:170352556-170352576 1.0000 20 chr21:45395175-45395195 1.0000 20 chr3:170587929-170587949 1.0000 20 chr1:10571131-10571151 1.0000 20 chr1:61784616-61784636 1.0000 20 chr17:76702502-76702522 1.0000 20 chr15:83501486-83501506 1.0000 20 chr8:59054047-59054067 1.0000 20 chr11:65269155-65269175 1.0000 20 chr1:94073645-94073665 1.0000 20 chr19:46461759-46461779 1.0000 20 chr11:128602626-12860264 1.0000 20 chr21:36238418-36238438 1.0000 20 chr19:42424277-42424297 1.0000 20 chr6:45891974-45891994 1.0000 20 chr15:31296723-31296743 1.0000 20 chr21:36346725-36346745 1.0000 20 chr1:210547363-210547383 1.0000 20 chr14:65672271-65672291 1.0000 20 chr20:30945575-30945595 1.0000 20 chr16:89980606-89980626 1.0000 20 chr16:29679367-29679387 1.0000 20 chr11:62623294-62623314 1.0000 20 chr17:62493345-62493365 1.0000 20 chr11:48028403-48028423 1.0000 20 chr2:43446275-43446295 1.0000 20 chr13:33415325-33415345 1.0000 20 chr2:61068176-61068196 1.0000 20 chr1:23039039-23039059 1.0000 20 chr11:3860753-3860773 1.0000 20 chr15:56664130-56664150 1.0000 20 chr15:91229875-91229895 1.0000 20 chr12:53613436-53613456 1.0000 20 chr6:74290268-74290288 1.0000 20 chr17:56406769-56406789 1.0000 20 chr8:43109350-43109370 1.0000 20 chr3:71136900-71136920 1.0000 20 chr1:147806739-147806759 1.0000 20 chrX:45618661-45618681 1.0000 20 chr2:199237139-199237159 1.0000 20 chr3:114598298-114598318 1.0000 20 chr1:146556142-146556162 1.0000 20 chr17:78198198-78198218 1.0000 20 chr2:38374194-38374214 1.0000 20 chr14:68742444-68742464 1.0000 20 chr6:16475321-16475341 1.0000 20 chr2:33722476-33722496 1.0000 20 chr17:6136826-6136846 1.0000 20 chr6:145671397-145671417 1.0000 20 chr17:38717306-38717326 1.0000 20 chr13:114833063-11483308 1.0000 20 chr10:61846845-61846865 1.0000 20 chr16:71642377-71642397 1.0000 20 chr7:76895909-76895929 1.0000 20 chr1:1265286-1265306 1.0000 20 chr2:121035625-121035645 1.0000 20 chr7:28247260-28247280 1.0000 20 chr5:90568885-90568905 1.0000 20 chr22:39919209-39919229 1.0000 20 chr10:11277980-11278000 1.0000 20 chr8:116440013-116440033 1.0000 20 chr1:11000328-11000348 1.0000 20 chr11:106914526-10691454 1.0000 20 chr1:101644564-101644584 1.0000 20 chr8:38626258-38626278 1.0000 20 chr17:8884939-8884959 1.0000 20 chr20:47158289-47158309 1.0000 20 chr4:40230419-40230439 1.0000 20 chr12:65271285-65271305 1.0000 20 chr3:32535750-32535770 1.0000 20 chr3:170350798-170350818 1.0000 20 chr17:78954478-78954498 1.0000 20 chr16:1777401-1777421 1.0000 20 chr3:177055705-177055725 1.0000 20 chr9:2055374-2055394 1.0000 20 chr10:92753312-92753332 1.0000 20 chr17:79943020-79943040 1.0000 20 chr14:47238706-47238726 1.0000 20 chr7:11372328-11372348 1.0000 20 chr15:44600741-44600761 1.0000 20 chr1:17231874-17231894 1.0000 20 chr18:11145938-11145958 1.0000 20 chr9:92035222-92035242 1.0000 20 chr1:25226783-25226803 1.0000 20 chr8:105677613-105677633 1.0000 20 chr4:26131984-26132004 1.0000 20 chrX:1536026-1536046 1.0000 20 chr7:80267831-80267851 1.0000 20 chr2:135094103-135094123 1.0000 20 chr13:79578260-79578280 1.0000 20 chr5:108497935-108497955 1.0000 20 chr5:142775757-142775777 1.0000 20 chr6:6643714-6643734 1.0000 20 chr13:48809357-48809377 1.0000 20 chr1:243759824-243759844 1.0000 20 chr9:98585239-98585259 1.0000 20 chr3:129040253-129040273 1.0000 20 chr3:152455017-152455037 1.0000 20 chr15:80271316-80271336 1.0000 20 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/GM12878/inference_raw/MEME/RankLinear0.6_10_STAT5A/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/STAT5A.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 5000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 5000 norand= no csites= 1000 Letter frequencies in dataset: A 0.268 C 0.236 G 0.228 T 0.268 Background letter frequencies (from file dataset with add-one prior applied): A 0.268 C 0.236 G 0.228 T 0.268 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TGTGTGTG MEME-1 width = 8 sites = 27 llr = 248 E-value = 1.4e-027 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGTGTGTG MEME-1 Description -------------------------------------------------------------------------------- Simplified A :1::21:: pos.-specific C ::::1:1: probability G :9:a:9:a matrix T a:a:7:9: bits 2.1 * * 1.9 * * 1.7 **** * * 1.5 **** *** Relative 1.3 **** *** Entropy 1.1 **** *** (13.3 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGTGTGTG consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGTGTG MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:38626258-38626278 6 1.39e-05 gaaac tgtgtgtg ggaggta chr1:207097667-207097687 1 1.39e-05 . tgtgtgtg gtgtgtggct chr19:2336636-2336656 11 1.39e-05 tgtgtgcgtg tgtgtgtg ca chr13:114268219-11426823 4 1.39e-05 gcg tgtgtgtg catgcgtgt chr1:226837142-226837162 3 1.39e-05 cg tgtgtgtg catgtgtgat chr15:101326465-10132648 8 1.39e-05 gtgtcaa tgtgtgtg agtga chr16:89980943-89980963 12 1.39e-05 ggtgcacatt tgtgtgtg t chr7:154997868-154997888 9 1.39e-05 tgtttgtg tgtgtgtg tcag chr1:207097467-207097487 9 1.39e-05 gttatgag tgtgtgtg ttct chr19:6532625-6532645 8 1.39e-05 gtgtttg tgtgtgtg tgtgt chr1:6093418-6093438 2 1.39e-05 g tgtgtgtg catatgtgtg chr18:46546117-46546137 9 1.39e-05 Atgtgtga tgtgtgtg gtgt chr22:37704837-37704857 5 1.39e-05 tgca tgtgtgtg catgtatg chr17:78954478-78954498 4 2.79e-05 gtg tgtgagtg aatgagtgg chr2:121035625-121035645 13 2.79e-05 tgtgagcgtg tgtgagtg chr17:78198198-78198218 13 2.79e-05 tgagagtgag tgtgagtg chr22:39157950-39157970 6 2.79e-05 gaatg tgtgagtg tgcgtgt chr15:91229875-91229895 2 4.02e-05 G TGTGCGTG TGTATACCCT chr12:104882447-10488246 1 5.65e-05 . tgtgtatg cgtctgtgta chr17:78264214-78264234 1 6.88e-05 . tgtgtgcg agtgtgcgcg chr1:15762040-15762060 2 6.88e-05 g tgtgtgcg tCGCCTGTCC chr16:89980606-89980626 6 8.52e-05 gtatg tatgtgtg cacactt chr21:45378396-45378416 9 1.09e-04 TCGTTTTT Ggtgtgtg gtgt chr8:56901987-56902007 11 1.09e-04 CACTTCTCAG TGGGTGTG TT chr1:67637744-67637764 3 1.68e-04 GT TATGAGTG TAAAAATGTA chr9:130628278-130628298 3 1.68e-04 tg tgtgcatg tgtaaatgtg chr9:138542388-138542408 9 1.68e-04 tgtgttca tgtgcatg tgca -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGTGTG MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:38626258-38626278 1.4e-05 5_[+1]_7 chr1:207097667-207097687 1.4e-05 [+1]_12 chr19:2336636-2336656 1.4e-05 10_[+1]_2 chr13:114268219-11426823 1.4e-05 3_[+1]_9 chr1:226837142-226837162 1.4e-05 2_[+1]_10 chr15:101326465-10132648 1.4e-05 7_[+1]_5 chr16:89980943-89980963 1.4e-05 11_[+1]_1 chr7:154997868-154997888 1.4e-05 8_[+1]_4 chr1:207097467-207097487 1.4e-05 8_[+1]_4 chr19:6532625-6532645 1.4e-05 7_[+1]_5 chr1:6093418-6093438 1.4e-05 1_[+1]_11 chr18:46546117-46546137 1.4e-05 8_[+1]_4 chr22:37704837-37704857 1.4e-05 4_[+1]_8 chr17:78954478-78954498 2.8e-05 3_[+1]_9 chr2:121035625-121035645 2.8e-05 12_[+1] chr17:78198198-78198218 2.8e-05 12_[+1] chr22:39157950-39157970 2.8e-05 5_[+1]_7 chr15:91229875-91229895 4e-05 1_[+1]_11 chr12:104882447-10488246 5.7e-05 [+1]_12 chr17:78264214-78264234 6.9e-05 [+1]_12 chr1:15762040-15762060 6.9e-05 1_[+1]_11 chr16:89980606-89980626 8.5e-05 5_[+1]_7 chr21:45378396-45378416 0.00011 8_[+1]_4 chr8:56901987-56902007 0.00011 10_[+1]_2 chr1:67637744-67637764 0.00017 2_[+1]_10 chr9:130628278-130628298 0.00017 2_[+1]_10 chr9:138542388-138542408 0.00017 8_[+1]_4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGTGTG MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGTGTGTG width=8 seqs=27 chr8:38626258-38626278 ( 6) TGTGTGTG 1 chr1:207097667-207097687 ( 1) TGTGTGTG 1 chr19:2336636-2336656 ( 11) TGTGTGTG 1 chr13:114268219-11426823 ( 4) TGTGTGTG 1 chr1:226837142-226837162 ( 3) TGTGTGTG 1 chr15:101326465-10132648 ( 8) TGTGTGTG 1 chr16:89980943-89980963 ( 12) TGTGTGTG 1 chr7:154997868-154997888 ( 9) TGTGTGTG 1 chr1:207097467-207097487 ( 9) TGTGTGTG 1 chr19:6532625-6532645 ( 8) TGTGTGTG 1 chr1:6093418-6093438 ( 2) TGTGTGTG 1 chr18:46546117-46546137 ( 9) TGTGTGTG 1 chr22:37704837-37704857 ( 5) TGTGTGTG 1 chr17:78954478-78954498 ( 4) TGTGAGTG 1 chr2:121035625-121035645 ( 13) TGTGAGTG 1 chr17:78198198-78198218 ( 13) TGTGAGTG 1 chr22:39157950-39157970 ( 6) TGTGAGTG 1 chr15:91229875-91229895 ( 2) TGTGCGTG 1 chr12:104882447-10488246 ( 1) TGTGTATG 1 chr17:78264214-78264234 ( 1) TGTGTGCG 1 chr1:15762040-15762060 ( 2) TGTGTGCG 1 chr16:89980606-89980626 ( 6) TATGTGTG 1 chr21:45378396-45378416 ( 9) GGTGTGTG 1 chr8:56901987-56902007 ( 11) TGGGTGTG 1 chr1:67637744-67637764 ( 3) TATGAGTG 1 chr9:130628278-130628298 ( 3) TGTGCATG 1 chr9:138542388-138542408 ( 9) TGTGCATG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGTGTG MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.85576 E= 1.4e-027 -1140 -1140 -262 185 -186 -1140 202 -1140 -1140 -1140 -262 185 -1140 -1140 213 -1140 -54 -109 -1140 139 -127 -1140 196 -1140 -1140 -167 -1140 179 -1140 -1140 213 -1140 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGTGTG MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 27 E= 1.4e-027 0.000000 0.000000 0.037037 0.962963 0.074074 0.000000 0.925926 0.000000 0.000000 0.000000 0.037037 0.962963 0.000000 0.000000 1.000000 0.000000 0.185185 0.111111 0.000000 0.703704 0.111111 0.000000 0.888889 0.000000 0.000000 0.074074 0.000000 0.925926 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGTGTG MEME-1 regular expression -------------------------------------------------------------------------------- TGTGTGTG -------------------------------------------------------------------------------- Time 3.23 secs. ******************************************************************************** ******************************************************************************** MOTIF DCACWCAC MEME-2 width = 8 sites = 53 llr = 362 E-value = 2.1e-024 ******************************************************************************** -------------------------------------------------------------------------------- Motif DCACWCAC MEME-2 Description -------------------------------------------------------------------------------- Simplified A 3:a:6:a: pos.-specific C :7:6:a:7 probability G 33:31::1 matrix T 4::13::3 bits 2.1 * 1.9 * ** 1.7 * ** 1.5 * ** Relative 1.3 ** ** Entropy 1.1 ** ** (9.9 bits) 0.9 *** *** 0.6 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCACACAC consensus AG GT T sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DCACWCAC MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr5:33985475-33985495 6 1.60e-05 TTCTC TCACACAC ATTACAC chr11:111229288-11122930 5 1.60e-05 acac tcacacac tcacactc chr11:47379751-47379771 12 1.60e-05 cacacttata tcacacac a chr9:137171148-137171168 13 1.60e-05 acatgctcgt tcacacac chr11:111229078-11122909 7 1.60e-05 acactc tcacacac tcacac chr17:6136826-6136846 11 4.56e-05 actcatatgc gcacacac at chr19:2557161-2557181 3 4.56e-05 gc gcacacac gtacacacaA chr6:167061564-167061584 10 4.56e-05 catggtcat acacacac gct chr21:46324556-46324576 8 4.56e-05 cacacat acacacac caaac chr10:135162745-13516276 5 4.56e-05 acac acacacac ccaagccc chr17:8732880-8732900 5 4.56e-05 acat acacacac agacacac chr16:28100870-28100890 2 4.56e-05 c acacacac cacacacata chr19:1389190-1389210 6 4.56e-05 catgt gcacacac gcttgca chr17:8732680-8732700 13 4.56e-05 atgcatggat acacacac chr17:65050972-65050992 12 4.56e-05 agacacagag acacacac t chr3:170587929-170587949 11 6.16e-05 AAGACATCGC TCACTCAC CG chr5:142775757-142775777 5 7.71e-05 AAAA TGACACAC CTGAATAC chr2:240212401-240212421 2 1.22e-04 c acactcac atacgcactc chr6:11319752-11319772 3 1.22e-04 gc acactcac actaacatgc chr20:33153690-33153710 3 1.51e-04 TT AGacacac atgcttgcac chr8:116440013-116440033 9 1.98e-04 TGAGGTCG ACAGACAC AGTC chr3:16549138-16549158 5 2.62e-04 acat gcacacat ccacaaac chr19:3831029-3831049 10 2.62e-04 tacgtgcaa gcacacat aca chr4:881221-881241 8 2.62e-04 ggcactc gcacacat gcata chr8:59054047-59054067 13 3.06e-04 TTTCCTGCTG TGAGACAC chr2:68666188-68666208 12 3.06e-04 tggttttatt tgagacac a chrX:1536026-1536046 11 3.66e-04 cacaACCACA GCAGTCAC AT chr6:74290268-74290288 7 3.66e-04 CTCTCT GCAGTCAC GCAGAA chr3:127406237-127406257 7 3.66e-04 cctcat tcactcat gatctc chr12:6927042-6927062 13 3.66e-04 acttacacat tcacgcac chr17:79943020-79943040 2 4.88e-04 t gcacgcac atgcgcacac chr8:29949278-29949298 7 4.88e-04 acacat gcacgcac aaacgc chr8:105677613-105677633 5 5.03e-04 atgc tgagtcac actgatac chr16:71642377-71642397 2 5.03e-04 A TGAGTCAC TGATGGTCAA chr20:61168322-61168342 10 5.51e-04 tgcacaccc agacacat gct chr21:26935399-26935419 1 5.51e-04 . tcacacag cAGATCTAGG chr12:124963847-12496386 9 5.51e-04 acatgcac ggacacat gcac chr19:42424277-42424297 12 5.83e-04 acatgcgctc acagacat g chr4:104419623-104419643 3 6.41e-04 CA TGACTCAT GGCAGTAGTA chr9:136780826-136780846 2 8.08e-04 c agacgcac acgatgtaca chr17:74273747-74273767 12 8.08e-04 acacacgtac tcatacac a chr21:26952616-26952636 4 8.80e-04 act acaggcac ccaccacca chr13:114833063-11483308 11 1.00e-03 TTGGAGCTGT GGAGACAT TT chr16:2011043-2011063 1 1.00e-03 . ACACTCAG GAAGTTCTCC chr8:144636747-144636767 10 1.00e-03 cacgcacgt gcatacac gcg chr15:83501486-83501506 5 1.11e-03 AGAA TGAGTCAT CACTGACT chr6:45888726-45888746 4 1.11e-03 AAA TGAGTCAT GTAGCTTTT chr7:124533382-124533402 4 1.11e-03 TTT TGAGTCAT AAATGGTAT chr15:57252459-57252479 10 1.11e-03 GGTTTAGTT TGAGTCAT TTT chr10:65467265-65467285 7 1.17e-03 TAGTCC TGACTCAG TTCCCA chrX:45618661-45618681 4 1.29e-03 TAG TCAGTCAG TTTCAGCCA chr21:35956597-35956617 2 1.29e-03 T GCATTCAC CAAACAACTT chr6:137605364-137605384 6 1.29e-03 aggag agaGTCAT AGTCATC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DCACWCAC MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr5:33985475-33985495 1.6e-05 5_[+2]_7 chr11:111229288-11122930 1.6e-05 4_[+2]_8 chr11:47379751-47379771 1.6e-05 11_[+2]_1 chr9:137171148-137171168 1.6e-05 12_[+2] chr11:111229078-11122909 1.6e-05 6_[+2]_6 chr17:6136826-6136846 4.6e-05 10_[+2]_2 chr19:2557161-2557181 4.6e-05 2_[+2]_10 chr6:167061564-167061584 4.6e-05 9_[+2]_3 chr21:46324556-46324576 4.6e-05 7_[+2]_5 chr10:135162745-13516276 4.6e-05 4_[+2]_8 chr17:8732880-8732900 4.6e-05 4_[+2]_8 chr16:28100870-28100890 4.6e-05 1_[+2]_11 chr19:1389190-1389210 4.6e-05 5_[+2]_7 chr17:8732680-8732700 4.6e-05 12_[+2] chr17:65050972-65050992 4.6e-05 11_[+2]_1 chr3:170587929-170587949 6.2e-05 10_[+2]_2 chr5:142775757-142775777 7.7e-05 4_[+2]_8 chr2:240212401-240212421 0.00012 1_[+2]_11 chr6:11319752-11319772 0.00012 2_[+2]_10 chr20:33153690-33153710 0.00015 2_[+2]_10 chr8:116440013-116440033 0.0002 8_[+2]_4 chr3:16549138-16549158 0.00026 4_[+2]_8 chr19:3831029-3831049 0.00026 9_[+2]_3 chr4:881221-881241 0.00026 7_[+2]_5 chr8:59054047-59054067 0.00031 12_[+2] chr2:68666188-68666208 0.00031 11_[+2]_1 chrX:1536026-1536046 0.00037 10_[+2]_2 chr6:74290268-74290288 0.00037 6_[+2]_6 chr3:127406237-127406257 0.00037 6_[+2]_6 chr12:6927042-6927062 0.00037 12_[+2] chr17:79943020-79943040 0.00049 1_[+2]_11 chr8:29949278-29949298 0.00049 6_[+2]_6 chr8:105677613-105677633 0.0005 4_[+2]_8 chr16:71642377-71642397 0.0005 1_[+2]_11 chr20:61168322-61168342 0.00055 9_[+2]_3 chr21:26935399-26935419 0.00055 [+2]_12 chr12:124963847-12496386 0.00055 8_[+2]_4 chr19:42424277-42424297 0.00058 11_[+2]_1 chr4:104419623-104419643 0.00064 2_[+2]_10 chr9:136780826-136780846 0.00081 1_[+2]_11 chr17:74273747-74273767 0.00081 11_[+2]_1 chr21:26952616-26952636 0.00088 3_[+2]_9 chr13:114833063-11483308 0.001 10_[+2]_2 chr16:2011043-2011063 0.001 [+2]_12 chr8:144636747-144636767 0.001 9_[+2]_3 chr15:83501486-83501506 0.0011 4_[+2]_8 chr6:45888726-45888746 0.0011 3_[+2]_9 chr7:124533382-124533402 0.0011 3_[+2]_9 chr15:57252459-57252479 0.0011 9_[+2]_3 chr10:65467265-65467285 0.0012 6_[+2]_6 chrX:45618661-45618681 0.0013 3_[+2]_9 chr21:35956597-35956617 0.0013 1_[+2]_11 chr6:137605364-137605384 0.0013 5_[+2]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DCACWCAC MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF DCACWCAC width=8 seqs=53 chr5:33985475-33985495 ( 6) TCACACAC 1 chr11:111229288-11122930 ( 5) TCACACAC 1 chr11:47379751-47379771 ( 12) TCACACAC 1 chr9:137171148-137171168 ( 13) TCACACAC 1 chr11:111229078-11122909 ( 7) TCACACAC 1 chr17:6136826-6136846 ( 11) GCACACAC 1 chr19:2557161-2557181 ( 3) GCACACAC 1 chr6:167061564-167061584 ( 10) ACACACAC 1 chr21:46324556-46324576 ( 8) ACACACAC 1 chr10:135162745-13516276 ( 5) ACACACAC 1 chr17:8732880-8732900 ( 5) ACACACAC 1 chr16:28100870-28100890 ( 2) ACACACAC 1 chr19:1389190-1389210 ( 6) GCACACAC 1 chr17:8732680-8732700 ( 13) ACACACAC 1 chr17:65050972-65050992 ( 12) ACACACAC 1 chr3:170587929-170587949 ( 11) TCACTCAC 1 chr5:142775757-142775777 ( 5) TGACACAC 1 chr2:240212401-240212421 ( 2) ACACTCAC 1 chr6:11319752-11319772 ( 3) ACACTCAC 1 chr20:33153690-33153710 ( 3) AGACACAC 1 chr8:116440013-116440033 ( 9) ACAGACAC 1 chr3:16549138-16549158 ( 5) GCACACAT 1 chr19:3831029-3831049 ( 10) GCACACAT 1 chr4:881221-881241 ( 8) GCACACAT 1 chr8:59054047-59054067 ( 13) TGAGACAC 1 chr2:68666188-68666208 ( 12) TGAGACAC 1 chrX:1536026-1536046 ( 11) GCAGTCAC 1 chr6:74290268-74290288 ( 7) GCAGTCAC 1 chr3:127406237-127406257 ( 7) TCACTCAT 1 chr12:6927042-6927062 ( 13) TCACGCAC 1 chr17:79943020-79943040 ( 2) GCACGCAC 1 chr8:29949278-29949298 ( 7) GCACGCAC 1 chr8:105677613-105677633 ( 5) TGAGTCAC 1 chr16:71642377-71642397 ( 2) TGAGTCAC 1 chr20:61168322-61168342 ( 10) AGACACAT 1 chr21:26935399-26935419 ( 1) TCACACAG 1 chr12:124963847-12496386 ( 9) GGACACAT 1 chr19:42424277-42424297 ( 12) ACAGACAT 1 chr4:104419623-104419643 ( 3) TGACTCAT 1 chr9:136780826-136780846 ( 2) AGACGCAC 1 chr17:74273747-74273767 ( 12) TCATACAC 1 chr21:26952616-26952636 ( 4) ACAGGCAC 1 chr13:114833063-11483308 ( 11) GGAGACAT 1 chr16:2011043-2011063 ( 1) ACACTCAG 1 chr8:144636747-144636767 ( 10) GCATACAC 1 chr15:83501486-83501506 ( 5) TGAGTCAT 1 chr6:45888726-45888746 ( 4) TGAGTCAT 1 chr7:124533382-124533402 ( 4) TGAGTCAT 1 chr15:57252459-57252479 ( 10) TGAGTCAT 1 chr10:65467265-65467285 ( 7) TGACTCAG 1 chrX:45618661-45618681 ( 4) TCAGTCAG 1 chr21:35956597-35956617 ( 2) GCATTCAC 1 chr6:137605364-137605384 ( 6) AGAGTCAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DCACWCAC MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 7.10736 E= 2.1e-024 26 -1237 21 63 -1237 152 49 -1237 190 -1237 -1237 -1237 -1237 144 41 -224 108 -1237 -127 34 -1237 208 -1237 -1237 190 -1237 -1237 -1237 -1237 148 -159 -2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DCACWCAC MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 53 E= 2.1e-024 0.320755 0.000000 0.264151 0.415094 0.000000 0.679245 0.320755 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.641509 0.301887 0.056604 0.566038 0.000000 0.094340 0.339623 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.660377 0.075472 0.264151 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif DCACWCAC MEME-2 regular expression -------------------------------------------------------------------------------- [TAG][CG]A[CG][AT]CA[CT] -------------------------------------------------------------------------------- Time 4.02 secs. ******************************************************************************** ******************************************************************************** MOTIF CATGTGTG MEME-3 width = 8 sites = 8 llr = 75 E-value = 1.8e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CATGTGTG MEME-3 Description -------------------------------------------------------------------------------- Simplified A :a13:1:: pos.-specific C a:::1::: probability G :::8:9:a matrix T ::9:9:a: bits 2.1 * * 1.9 ** ** 1.7 ** ** 1.5 ** *** Relative 1.3 ******** Entropy 1.1 ******** (13.6 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CATGTGTG consensus A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGTGTG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr19:46461759-46461779 9 1.44e-05 tgtgtaag catgtgtg acaa chr1:226837142-226837162 11 1.44e-05 cgtgtgtgtg catgtgtg at chr2:121035424-121035444 10 1.44e-05 gaacatgag catgtgtg aat chr17:62077126-62077146 12 3.14e-05 tgtgtacatg catatgtg t chr1:6093418-6093438 10 3.14e-05 gtgtgtgtg catatgtg tgc chr13:114268219-11426823 12 4.41e-05 cgtgtgtgtg catgcgtg t chr1:226920880-226920900 10 5.85e-05 aagtgtaag caagtgtg agc chr22:37704837-37704857 13 7.55e-05 catgtgtgtg catgtatg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGTGTG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:46461759-46461779 1.4e-05 8_[+3]_4 chr1:226837142-226837162 1.4e-05 10_[+3]_2 chr2:121035424-121035444 1.4e-05 9_[+3]_3 chr17:62077126-62077146 3.1e-05 11_[+3]_1 chr1:6093418-6093438 3.1e-05 9_[+3]_3 chr13:114268219-11426823 4.4e-05 11_[+3]_1 chr1:226920880-226920900 5.9e-05 9_[+3]_3 chr22:37704837-37704857 7.5e-05 12_[+3] -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGTGTG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CATGTGTG width=8 seqs=8 chr19:46461759-46461779 ( 9) CATGTGTG 1 chr1:226837142-226837162 ( 11) CATGTGTG 1 chr2:121035424-121035444 ( 10) CATGTGTG 1 chr17:62077126-62077146 ( 12) CATATGTG 1 chr1:6093418-6093438 ( 10) CATATGTG 1 chr13:114268219-11426823 ( 12) CATGCGTG 1 chr1:226920880-226920900 ( 10) CAAGTGTG 1 chr22:37704837-37704857 ( 13) CATGTATG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGTGTG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.66267 E= 1.8e+002 -965 208 -965 -965 190 -965 -965 -965 -110 -965 -965 171 -10 -965 172 -965 -965 -92 -965 171 -110 -965 194 -965 -965 -965 -965 190 -965 -965 213 -965 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGTGTG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 8 E= 1.8e+002 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.125000 0.000000 0.000000 0.875000 0.250000 0.000000 0.750000 0.000000 0.000000 0.125000 0.000000 0.875000 0.125000 0.000000 0.875000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CATGTGTG MEME-3 regular expression -------------------------------------------------------------------------------- CAT[GA]TGTG -------------------------------------------------------------------------------- Time 4.79 secs. ******************************************************************************** ******************************************************************************** MOTIF KGARGGAW MEME-4 width = 8 sites = 10 llr = 87 E-value = 3.5e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif KGARGGAW MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::a4::a3 pos.-specific C :::::::1 probability G 6a:6aa:1 matrix T 4::::::5 bits 2.1 * ** 1.9 ** *** 1.7 ** *** 1.5 ** *** Relative 1.3 ** *** Entropy 1.1 ******* (12.6 bits) 0.9 ******* 0.6 ******* 0.4 ******* 0.2 ******** 0.0 -------- Multilevel GGAGGGAT consensus T A A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGARGGAW MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:1915028-1915048 13 1.19e-05 atggatgaat ggagggat chr22:39919209-39919229 11 5.16e-05 CTTACGGGGT GGAAGGAT GA chr1:150540000-150540020 10 5.16e-05 TTTGCCTCA TGAGGGAT TTC chr6:412344-412364 1 5.16e-05 . GGAAGGat ttatgtcctg chr3:71133109-71133129 13 7.95e-05 AAGCACTGCC TGAGGGAA chr5:403156-403176 12 7.95e-05 GGATAAAGAA GGaaggaa g chr9:34652544-34652564 1 7.95e-05 . TGAGGGAA TGTGTTTTGG chr1:117087610-117087630 5 9.59e-05 TCAC TGAAGGAT AAAAGGCA chr4:185393799-185393819 12 1.06e-04 AGGAGCAACC GGAGGGAG G chr17:8804161-8804181 9 1.16e-04 TGAGCTGA GGAGGGAC AGCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGARGGAW MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:1915028-1915048 1.2e-05 12_[+4] chr22:39919209-39919229 5.2e-05 10_[+4]_2 chr1:150540000-150540020 5.2e-05 9_[+4]_3 chr6:412344-412364 5.2e-05 [+4]_12 chr3:71133109-71133129 7.9e-05 12_[+4] chr5:403156-403176 7.9e-05 11_[+4]_1 chr9:34652544-34652564 7.9e-05 [+4]_12 chr1:117087610-117087630 9.6e-05 4_[+4]_8 chr4:185393799-185393819 0.00011 11_[+4]_1 chr17:8804161-8804181 0.00012 8_[+4]_4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGARGGAW MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KGARGGAW width=8 seqs=10 chr11:1915028-1915048 ( 13) GGAGGGAT 1 chr22:39919209-39919229 ( 11) GGAAGGAT 1 chr1:150540000-150540020 ( 10) TGAGGGAT 1 chr6:412344-412364 ( 1) GGAAGGAT 1 chr3:71133109-71133129 ( 13) TGAGGGAA 1 chr5:403156-403176 ( 12) GGAAGGAA 1 chr9:34652544-34652564 ( 1) TGAGGGAA 1 chr1:117087610-117087630 ( 5) TGAAGGAT 1 chr4:185393799-185393819 ( 12) GGAGGGAG 1 chr17:8804161-8804181 ( 9) GGAGGGAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGARGGAW MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 9.81663 E= 3.5e+002 -997 -997 140 58 -997 -997 213 -997 190 -997 -997 -997 58 -997 140 -997 -997 -997 213 -997 -997 -997 213 -997 190 -997 -997 -997 16 -124 -118 90 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGARGGAW MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 10 E= 3.5e+002 0.000000 0.000000 0.600000 0.400000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.600000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.300000 0.100000 0.100000 0.500000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGARGGAW MEME-4 regular expression -------------------------------------------------------------------------------- [GT]GA[GA]GGA[TA] -------------------------------------------------------------------------------- Time 5.53 secs. ******************************************************************************** ******************************************************************************** MOTIF TGAGCGTG MEME-5 width = 8 sites = 6 llr = 57 E-value = 3.3e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGAGCGTG MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::7:2::: pos.-specific C ::2:8::: probability G :a:a:8:a matrix T a:2::2a: bits 2.1 * * * 1.9 ** * ** 1.7 ** * ** 1.5 ** ***** Relative 1.3 ** ***** Entropy 1.1 ** ***** (13.7 bits) 0.9 ** ***** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGAGCGTG consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGAGCGTG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:121035625-121035645 5 1.23e-05 aatg tgagcgtg tgtgagtg chr21:45668508-45668528 7 1.23e-05 TATGGA TGAGCGTG CAAGTG chr17:78264214-78264234 13 2.31e-05 tgtgcgagtg tgcgcgtg chr19:2336636-2336656 3 3.54e-05 tg tgtgcgtg tgtgtgtgca chr17:78198198-78198218 3 4.93e-05 tg tgagagtg agtgtgagtg chr1:89506938-89506958 12 6.37e-05 tgaggcttga tgagcttg t -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGAGCGTG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:121035625-121035645 1.2e-05 4_[+5]_8 chr21:45668508-45668528 1.2e-05 6_[+5]_6 chr17:78264214-78264234 2.3e-05 12_[+5] chr19:2336636-2336656 3.5e-05 2_[+5]_10 chr17:78198198-78198218 4.9e-05 2_[+5]_10 chr1:89506938-89506958 6.4e-05 11_[+5]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGAGCGTG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGAGCGTG width=8 seqs=6 chr2:121035625-121035645 ( 5) TGAGCGTG 1 chr21:45668508-45668528 ( 7) TGAGCGTG 1 chr17:78264214-78264234 ( 13) TGCGCGTG 1 chr19:2336636-2336656 ( 3) TGTGCGTG 1 chr17:78198198-78198218 ( 3) TGAGAGTG 1 chr1:89506938-89506958 ( 12) TGAGCTTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGAGCGTG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 9.52677 E= 3.3e+003 -923 -923 -923 190 -923 -923 213 -923 131 -50 -923 -68 -923 -923 213 -923 -69 182 -923 -923 -923 -923 187 -68 -923 -923 -923 190 -923 -923 213 -923 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGAGCGTG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 6 E= 3.3e+003 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.666667 0.166667 0.000000 0.166667 0.000000 0.000000 1.000000 0.000000 0.166667 0.833333 0.000000 0.000000 0.000000 0.000000 0.833333 0.166667 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGAGCGTG MEME-5 regular expression -------------------------------------------------------------------------------- TGAGCGTG -------------------------------------------------------------------------------- Time 6.54 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:1937605-1937625 6.45e-01 20 chr11:1915028-1915048 2.77e-04 12_[+4(1.19e-05)] chr8:142118403-142118423 9.39e-01 20 chr11:111229078-11122909 6.63e-02 6_[+2(1.60e-05)]_6 chr19:4815176-4815196 5.37e-01 20 chr1:207097266-207097286 3.79e-04 20 chr4:881221-881241 2.69e-02 20 chr22:39157950-39157970 3.25e-06 5_[+1(2.79e-05)]_7 chr14:106171987-10617200 8.97e-01 20 chr6:11319752-11319772 4.01e-02 20 chr17:65050972-65050992 9.58e-02 11_[+2(4.56e-05)]_1 chr17:8732680-8732700 2.59e-05 12_[+2(4.56e-05)] chr20:36034888-36034908 6.48e-01 20 chr8:11418285-11418305 8.17e-01 20 chr19:1389190-1389210 1.90e-03 5_[+2(4.56e-05)]_7 chr19:3831029-3831049 2.66e-02 20 chr22:37704837-37704857 5.19e-07 4_[+1(1.39e-05)]_[+3(7.55e-05)] chr1:15762040-15762060 3.65e-03 1_[+1(6.88e-05)]_11 chr19:40170960-40170980 3.08e-01 20 chr16:28100870-28100890 6.90e-02 1_[+2(4.56e-05)]_11 chr12:6927042-6927062 1.36e-01 20 chr18:60988174-60988194 1.33e-01 20 chr3:127406237-127406257 1.77e-01 20 chr12:124963847-12496386 5.41e-03 20 chr21:45668508-45668528 3.42e-04 6_[+5(1.23e-05)]_6 chr20:44973337-44973357 5.21e-01 20 chr13:111526463-11152648 8.50e-02 20 chr21:26935399-26935419 1.10e-01 20 chr9:34652544-34652564 2.52e-03 [+4(7.95e-05)]_12 chr17:74273747-74273767 2.35e-01 20 chr9:138542388-138542408 2.47e-03 20 chr18:46546117-46546137 8.70e-06 8_[+1(1.39e-05)]_4 chr17:62224368-62224388 2.23e-02 20 chr21:26952616-26952636 3.95e-01 20 chr9:137171148-137171168 2.78e-03 12_[+2(1.60e-05)] chr2:121035424-121035444 2.49e-05 9_[+3(1.44e-05)]_3 chr1:6093418-6093438 3.35e-06 1_[+1(1.39e-05)]_[+3(3.14e-05)]_3 chr6:296611-296631 3.52e-01 20 chr19:6532625-6532645 3.35e-04 5_[+1(1.39e-05)]_7 chr8:93284911-93284931 7.91e-01 20 chr6:412344-412364 5.06e-03 [+4(5.16e-05)]_12 chr4:185393799-185393819 3.75e-02 20 chr7:24795441-24795461 5.88e-01 20 chr11:47379751-47379771 3.05e-02 11_[+2(1.60e-05)]_1 chr1:207097467-207097487 5.04e-05 8_[+1(1.39e-05)]_4 chr9:92714900-92714920 9.84e-01 20 chr7:154997868-154997888 1.14e-04 4_[+1(1.39e-05)]_8 chr15:57252459-57252479 2.73e-02 20 chr16:89980943-89980963 1.06e-05 11_[+1(1.39e-05)]_1 chr1:31342101-31342121 7.84e-01 20 chr2:201997451-201997471 1.38e-01 20 chr17:8732880-8732900 6.88e-02 4_[+2(4.56e-05)]_8 chr9:130628278-130628298 3.30e-04 20 chr3:16549138-16549158 1.26e-01 20 chr10:135162745-13516276 1.16e-01 [+2(4.56e-05)]_12 chr17:78264214-78264234 1.09e-05 [+1(6.88e-05)]_4_[+5(2.31e-05)] chr21:26950799-26950819 4.09e-01 20 chr15:101326465-10132648 4.42e-06 7_[+1(1.39e-05)]_5 chr21:46324556-46324576 6.83e-02 7_[+2(4.56e-05)]_5 chr22:23244158-23244178 3.83e-01 20 chr17:62077126-62077146 2.41e-04 11_[+3(3.14e-05)]_1 chr6:26056132-26056152 8.27e-01 20 chr6:167061564-167061584 4.22e-02 9_[+2(4.56e-05)]_3 chr11:497456-497476 9.82e-01 20 chr8:29949278-29949298 1.22e-02 20 chr1:183811811-183811831 5.11e-01 20 chr20:33153690-33153710 3.30e-03 20 chr20:61168322-61168342 2.01e-01 20 chr7:97762704-97762724 9.13e-01 20 chr1:67637744-67637764 1.74e-03 20 chr2:88315876-88315896 7.23e-01 20 chr1:226920880-226920900 5.23e-03 9_[+3(5.85e-05)]_3 chr7:124533382-124533402 4.34e-03 20 chr11:65197563-65197583 3.06e-01 20 chr2:68666188-68666208 4.16e-02 20 chr21:26952964-26952984 1.59e-01 20 chr3:188027671-188027691 6.53e-04 20 chr8:11418495-11418515 2.18e-01 20 chr6:137605364-137605384 1.72e-02 20 chr7:148610412-148610432 8.82e-02 20 chr1:117087610-117087630 7.25e-02 4_[+4(9.59e-05)]_8 chr13:111526665-11152668 4.43e-01 20 chr8:142046316-142046336 1.93e-01 20 chr2:191827073-191827093 8.46e-01 20 chr8:144636747-144636767 1.64e-02 20 chr1:83974292-83974312 8.45e-01 20 chr17:27052525-27052545 6.12e-01 20 chr2:100752945-100752965 2.04e-01 20 chr22:46075372-46075392 9.95e-01 20 chr1:226837142-226837162 4.25e-07 2_[+1(1.39e-05)]_[+3(1.44e-05)]_2 chrX:47489658-47489678 5.06e-02 20 chr3:119269510-119269530 8.90e-01 20 chr1:160139600-160139620 1.34e-01 20 chr6:45888726-45888746 4.13e-02 20 chr10:4174075-4174095 2.50e-01 20 chr6:26031926-26031946 6.71e-01 20 chr8:56901987-56902007 8.46e-03 20 chr19:2557161-2557181 4.87e-02 2_[+2(4.56e-05)]_10 chr18:51675553-51675573 9.95e-01 20 chr6:26045980-26046000 6.84e-01 20 chr10:65467265-65467285 3.93e-01 20 chr5:95261827-95261847 3.70e-01 20 chr2:240212401-240212421 7.07e-02 20 chr20:40091221-40091241 4.07e-01 20 chr11:111229288-11122930 6.52e-02 4_[+2(1.60e-05)]_8 chr14:71990931-71990951 5.53e-01 20 chr12:104882447-10488246 3.77e-03 [+1(5.65e-05)]_4_[+1(5.65e-05)] chr9:136780826-136780846 1.53e-01 20 chr13:114268219-11426823 1.99e-06 3_[+1(1.39e-05)]_[+3(4.41e-05)]_1 chr5:403156-403176 6.34e-02 11_[+4(7.95e-05)]_1 chr14:68730426-68730446 6.00e-01 20 chr6:42307904-42307924 3.96e-01 20 chr17:8804161-8804181 8.99e-03 20 chr18:21589809-21589829 2.58e-01 20 chr4:104419623-104419643 6.91e-02 20 chr1:174784703-174784723 3.12e-01 20 chr19:2336636-2336656 3.65e-06 8_[+1(1.39e-05)]_4 chr8:60964352-60964372 9.99e-01 20 chr16:84999651-84999671 5.43e-01 20 chr1:247569673-247569693 1.26e-01 20 chr1:89506938-89506958 4.25e-03 11_[+5(6.37e-05)]_1 chr1:29289130-29289150 8.93e-01 20 chr13:50819291-50819311 8.42e-01 20 chr9:119714254-119714274 5.17e-01 20 chr1:79506549-79506569 9.93e-01 20 chr3:71133109-71133129 2.50e-02 12_[+4(7.95e-05)] chr4:71544253-71544273 4.14e-01 20 chr16:2011043-2011063 2.67e-01 20 chr1:207097667-207097687 2.40e-04 [+1(1.39e-05)]_12 chr1:150540000-150540020 1.39e-03 9_[+4(5.16e-05)]_3 chr16:75413427-75413447 4.60e-01 20 chr21:26951001-26951021 7.77e-01 20 chr2:100864218-100864238 7.39e-01 20 chr6:132006695-132006715 1.76e-01 20 chr21:45378396-45378416 6.55e-03 20 chr14:69533647-69533667 8.15e-01 20 chr1:209943968-209943988 3.18e-02 20 chr2:142271594-142271614 9.75e-01 20 chr12:95482325-95482345 6.10e-03 20 chr1:66865733-66865753 9.10e-01 20 chr5:95616025-95616045 1.34e-01 20 chr8:146012811-146012831 9.84e-01 20 chr5:33985475-33985495 3.58e-02 5_[+2(1.60e-05)]_7 chr4:76979664-76979684 5.54e-01 20 chr2:181993090-181993110 7.18e-01 20 chr19:7197834-7197854 1.49e-01 20 chr6:74224303-74224323 5.44e-01 20 chr8:60027887-60027907 9.67e-01 20 chr21:35956597-35956617 4.00e-01 20 chr13:24368920-24368940 8.83e-01 20 chr7:42909154-42909174 3.61e-01 20 chr3:170352556-170352576 7.51e-01 20 chr21:45395175-45395195 4.88e-02 20 chr3:170587929-170587949 1.23e-01 10_[+2(6.16e-05)]_2 chr1:10571131-10571151 1.11e-02 20 chr1:61784616-61784636 1.38e-01 20 chr17:76702502-76702522 3.79e-02 20 chr15:83501486-83501506 7.36e-02 20 chr8:59054047-59054067 1.58e-02 20 chr11:65269155-65269175 5.07e-01 20 chr1:94073645-94073665 7.35e-01 20 chr19:46461759-46461779 1.06e-04 8_[+3(1.44e-05)]_4 chr11:128602626-12860264 8.96e-01 20 chr21:36238418-36238438 2.29e-01 20 chr19:42424277-42424297 2.05e-02 20 chr6:45891974-45891994 9.22e-01 20 chr15:31296723-31296743 9.81e-01 20 chr21:36346725-36346745 9.29e-01 20 chr1:210547363-210547383 6.68e-01 20 chr14:65672271-65672291 3.41e-01 20 chr20:30945575-30945595 8.35e-01 20 chr16:89980606-89980626 1.20e-04 5_[+1(8.52e-05)]_7 chr16:29679367-29679387 2.56e-01 20 chr11:62623294-62623314 5.13e-01 20 chr17:62493345-62493365 7.33e-01 20 chr11:48028403-48028423 3.24e-01 20 chr2:43446275-43446295 9.37e-01 20 chr13:33415325-33415345 3.90e-01 20 chr2:61068176-61068196 5.63e-01 20 chr1:23039039-23039059 6.22e-01 20 chr11:3860753-3860773 9.91e-01 20 chr15:56664130-56664150 9.24e-01 20 chr15:91229875-91229895 6.51e-05 1_[+5(3.54e-05)]_11 chr12:53613436-53613456 9.21e-02 20 chr6:74290268-74290288 2.62e-01 20 chr17:56406769-56406789 3.36e-01 20 chr8:43109350-43109370 8.06e-01 20 chr3:71136900-71136920 8.25e-01 20 chr1:147806739-147806759 4.74e-01 20 chrX:45618661-45618681 4.22e-01 20 chr2:199237139-199237159 3.95e-01 20 chr3:114598298-114598318 1.77e-01 20 chr1:146556142-146556162 9.99e-01 20 chr17:78198198-78198218 1.61e-05 2_[+5(4.93e-05)]_2_[+1(2.79e-05)] chr2:38374194-38374214 5.30e-01 20 chr14:68742444-68742464 7.44e-01 20 chr6:16475321-16475341 9.90e-01 20 chr2:33722476-33722496 4.83e-01 20 chr17:6136826-6136846 7.33e-04 10_[+2(4.56e-05)]_2 chr6:145671397-145671417 6.31e-01 20 chr17:38717306-38717326 8.24e-01 20 chr13:114833063-11483308 2.53e-02 20 chr10:61846845-61846865 6.20e-01 20 chr16:71642377-71642397 7.61e-02 20 chr7:76895909-76895929 1.97e-01 20 chr1:1265286-1265306 6.51e-02 20 chr2:121035625-121035645 1.15e-06 4_[+5(1.23e-05)]_[+1(2.79e-05)] chr7:28247260-28247280 6.12e-01 20 chr5:90568885-90568905 7.04e-01 20 chr22:39919209-39919229 2.40e-02 10_[+4(5.16e-05)]_2 chr10:11277980-11278000 9.82e-01 20 chr8:116440013-116440033 3.36e-02 20 chr1:11000328-11000348 5.08e-01 20 chr11:106914526-10691454 9.83e-01 20 chr1:101644564-101644584 9.72e-01 20 chr8:38626258-38626278 2.58e-05 5_[+1(1.39e-05)]_7 chr17:8884939-8884959 8.31e-01 20 chr20:47158289-47158309 9.50e-01 20 chr4:40230419-40230439 4.89e-01 20 chr12:65271285-65271305 8.57e-01 20 chr3:32535750-32535770 9.32e-01 20 chr3:170350798-170350818 9.59e-01 20 chr17:78954478-78954498 5.13e-06 3_[+1(2.79e-05)]_9 chr16:1777401-1777421 4.10e-02 20 chr3:177055705-177055725 6.54e-01 20 chr9:2055374-2055394 9.91e-01 20 chr10:92753312-92753332 9.81e-01 20 chr17:79943020-79943040 4.56e-02 20 chr14:47238706-47238726 6.18e-01 20 chr7:11372328-11372348 3.26e-01 20 chr15:44600741-44600761 7.38e-01 20 chr1:17231874-17231894 4.99e-01 20 chr18:11145938-11145958 6.18e-01 20 chr9:92035222-92035242 5.68e-01 20 chr1:25226783-25226803 2.50e-02 20 chr8:105677613-105677633 1.17e-01 20 chr4:26131984-26132004 8.85e-01 20 chrX:1536026-1536046 3.13e-01 20 chr7:80267831-80267851 9.84e-01 20 chr2:135094103-135094123 1.90e-01 20 chr13:79578260-79578280 5.99e-01 20 chr5:108497935-108497955 5.88e-01 20 chr5:142775757-142775777 5.31e-02 4_[+2(7.71e-05)]_8 chr6:6643714-6643734 3.70e-01 20 chr13:48809357-48809377 4.23e-01 20 chr1:243759824-243759844 8.51e-01 20 chr9:98585239-98585259 9.99e-01 20 chr3:129040253-129040273 1.17e-01 20 chr3:152455017-152455037 2.76e-03 20 chr15:80271316-80271336 8.54e-01 20 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n04.farnam.hpc.yale.internal ********************************************************************************