******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/SKIL.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr7:129045499-129045519 1.0000 20 chr15:70593028-70593048 1.0000 20 chr1:119682206-119682226 1.0000 20 chr1:79086037-79086057 1.0000 20 chr2:11244394-11244414 1.0000 20 chr4:103474064-103474084 1.0000 20 chr13:113840769-11384078 1.0000 20 chr2:68441704-68441724 1.0000 20 chr19:51847944-51847964 1.0000 20 chr10:86090181-86090201 1.0000 20 chr1:200875056-200875076 1.0000 20 chr9:139894808-139894828 1.0000 20 chr19:50844521-50844541 1.0000 20 chr2:47729914-47729934 1.0000 20 chr3:122252865-122252885 1.0000 20 chr1:207588036-207588056 1.0000 20 chr22:20023837-20023857 1.0000 20 chr2:47924570-47924590 1.0000 20 chr11:107415986-10741600 1.0000 20 chr4:26320786-26320806 1.0000 20 chr1:161065985-161066005 1.0000 20 chr18:47485739-47485759 1.0000 20 chr8:120055688-120055708 1.0000 20 chr2:234428963-234428983 1.0000 20 chr7:41849997-41850017 1.0000 20 chr2:208014769-208014789 1.0000 20 chr7:23408110-23408130 1.0000 20 chr1:202587721-202587741 1.0000 20 chr2:113394307-113394327 1.0000 20 chr6:14110392-14110412 1.0000 20 chr3:146221684-146221704 1.0000 20 chr15:101675925-10167594 1.0000 20 chr13:30333019-30333039 1.0000 20 chr12:112211934-11221195 1.0000 20 chr6:36325832-36325852 1.0000 20 chr1:110786432-110786452 1.0000 20 chr22:40607002-40607022 1.0000 20 chr2:120188750-120188770 1.0000 20 chr1:66863064-66863084 1.0000 20 chr22:39512206-39512226 1.0000 20 chr2:111432955-111432975 1.0000 20 chr1:38518795-38518815 1.0000 20 chr7:2393994-2394014 1.0000 20 chr6:64093925-64093945 1.0000 20 chr21:46898228-46898248 1.0000 20 chr8:126123230-126123250 1.0000 20 chr19:47690117-47690137 1.0000 20 chr7:114556794-114556814 1.0000 20 chr11:60529076-60529096 1.0000 20 chr10:116286040-11628606 1.0000 20 chr12:96769764-96769784 1.0000 20 chr11:329603-329623 1.0000 20 chr12:104976771-10497679 1.0000 20 chr1:222013331-222013351 1.0000 20 chr14:94478328-94478348 1.0000 20 chr5:33848825-33848845 1.0000 20 chr11:67886757-67886777 1.0000 20 chr12:125166029-12516604 1.0000 20 chr1:210638210-210638230 1.0000 20 chr9:94909745-94909765 1.0000 20 chr22:43773035-43773055 1.0000 20 chr11:128666315-12866633 1.0000 20 chr1:221967145-221967165 1.0000 20 chr2:102371976-102371996 1.0000 20 chr10:121255989-12125600 1.0000 20 chr9:129770157-129770177 1.0000 20 chr7:99942668-99942688 1.0000 20 chr1:200849594-200849614 1.0000 20 chr17:37914460-37914480 1.0000 20 chr6:58313044-58313064 1.0000 20 chr1:221917237-221917257 1.0000 20 chr8:59080397-59080417 1.0000 20 chr1:43663566-43663586 1.0000 20 chr1:28496025-28496045 1.0000 20 chr2:242672087-242672107 1.0000 20 chr6:130835072-130835092 1.0000 20 chr11:119622589-11962260 1.0000 20 chr20:3888246-3888266 1.0000 20 chr1:183658989-183659009 1.0000 20 chr10:82796158-82796178 1.0000 20 chr14:50387836-50387856 1.0000 20 chr2:232537346-232537366 1.0000 20 chr9:35634676-35634696 1.0000 20 chr16:48570382-48570402 1.0000 20 chrX:47880843-47880863 1.0000 20 chr1:8537475-8537495 1.0000 20 chr17:44233408-44233428 1.0000 20 chr20:5655019-5655039 1.0000 20 chr9:130795549-130795569 1.0000 20 chr18:56209115-56209135 1.0000 20 chr1:94081586-94081606 1.0000 20 chr5:114545123-114545143 1.0000 20 chr14:81053801-81053821 1.0000 20 chr2:118813256-118813276 1.0000 20 chr15:51177575-51177595 1.0000 20 chr11:63399133-63399153 1.0000 20 chr7:86945774-86945794 1.0000 20 chr12:92987829-92987849 1.0000 20 chr6:150958173-150958193 1.0000 20 chr1:185287113-185287133 1.0000 20 chr7:92260761-92260781 1.0000 20 chr20:56293615-56293635 1.0000 20 chr9:71770417-71770437 1.0000 20 chr2:223316152-223316172 1.0000 20 chr17:1987136-1987156 1.0000 20 chr1:157566370-157566390 1.0000 20 chr17:33668815-33668835 1.0000 20 chr3:170070892-170070912 1.0000 20 chr12:82062502-82062522 1.0000 20 chr20:45903440-45903460 1.0000 20 chr11:121238317-12123833 1.0000 20 chr3:10265593-10265613 1.0000 20 chrX:122918797-122918817 1.0000 20 chr18:77196084-77196104 1.0000 20 chr2:135810193-135810213 1.0000 20 chr11:77342260-77342280 1.0000 20 chr1:2231947-2231967 1.0000 20 chr19:18949812-18949832 1.0000 20 chr4:151892170-151892190 1.0000 20 chr1:39991716-39991736 1.0000 20 chr12:26901794-26901814 1.0000 20 chr13:76112102-76112122 1.0000 20 chr1:25346069-25346089 1.0000 20 chr7:44673342-44673362 1.0000 20 chr10:121468593-12146861 1.0000 20 chr7:8008142-8008162 1.0000 20 chr19:11679240-11679260 1.0000 20 chr22:18589781-18589801 1.0000 20 chr16:68309712-68309732 1.0000 20 chr15:64303128-64303148 1.0000 20 chr5:173345063-173345083 1.0000 20 chr3:12437266-12437286 1.0000 20 chr3:15598215-15598235 1.0000 20 chr1:174938014-174938034 1.0000 20 chr17:7589761-7589781 1.0000 20 chr19:13010878-13010898 1.0000 20 chr10:85750085-85750105 1.0000 20 chr17:34136231-34136251 1.0000 20 chr19:6577623-6577643 1.0000 20 chr22:42000110-42000130 1.0000 20 chr11:44631134-44631154 1.0000 20 chr7:104909663-104909683 1.0000 20 chr2:120110174-120110194 1.0000 20 chr17:8762635-8762655 1.0000 20 chr12:27437956-27437976 1.0000 20 chr2:231122617-231122637 1.0000 20 chr19:50850712-50850732 1.0000 20 chr18:13612442-13612462 1.0000 20 chr1:181121275-181121295 1.0000 20 chr12:106696439-10669645 1.0000 20 chr19:10382376-10382396 1.0000 20 chr12:9913622-9913642 1.0000 20 chr20:2083121-2083141 1.0000 20 chr3:184925888-184925908 1.0000 20 chrX:70839188-70839208 1.0000 20 chr16:19305879-19305899 1.0000 20 chr6:15023859-15023879 1.0000 20 chr1:246064521-246064541 1.0000 20 chr16:12058937-12058957 1.0000 20 chr1:208108665-208108685 1.0000 20 chr21:16250239-16250259 1.0000 20 chr11:85959803-85959823 1.0000 20 chr15:80348490-80348510 1.0000 20 chr7:87104245-87104265 1.0000 20 chr16:10870320-10870340 1.0000 20 chr17:70418925-70418945 1.0000 20 chr19:7894883-7894903 1.0000 20 chr11:95785238-95785258 1.0000 20 chr6:90544935-90544955 1.0000 20 chr2:71588962-71588982 1.0000 20 chr4:38807396-38807416 1.0000 20 chr9:116282660-116282680 1.0000 20 chr19:14779165-14779185 1.0000 20 chr11:65905323-65905343 1.0000 20 chr19:43017164-43017184 1.0000 20 chr6:73359501-73359521 1.0000 20 chr14:77587910-77587930 1.0000 20 chr20:42219390-42219410 1.0000 20 chr19:35815313-35815333 1.0000 20 chr17:16311831-16311851 1.0000 20 chr2:158261073-158261093 1.0000 20 chr3:17193302-17193322 1.0000 20 chr8:114467352-114467372 1.0000 20 chr9:127054125-127054145 1.0000 20 chr6:34779185-34779205 1.0000 20 chr21:19192111-19192131 1.0000 20 chr11:1872357-1872377 1.0000 20 chr13:66712671-66712691 1.0000 20 chr11:118098731-11809875 1.0000 20 chr11:121446074-12144609 1.0000 20 chr21:38564465-38564485 1.0000 20 chr16:10391467-10391487 1.0000 20 chr6:399967-399987 1.0000 20 chr12:48279103-48279123 1.0000 20 chr7:87228762-87228782 1.0000 20 chr7:101577088-101577108 1.0000 20 chr7:17199268-17199288 1.0000 20 chr1:87915354-87915374 1.0000 20 chr1:59043980-59044000 1.0000 20 chr9:132751529-132751549 1.0000 20 chr10:5894541-5894561 1.0000 20 chr5:142598457-142598477 1.0000 20 chr20:50796242-50796262 1.0000 20 chr4:90022653-90022673 1.0000 20 chr3:45922744-45922764 1.0000 20 chr15:45174976-45174996 1.0000 20 chr20:56058511-56058531 1.0000 20 chr6:32995789-32995809 1.0000 20 chr6:114126477-114126497 1.0000 20 chr22:22222445-22222465 1.0000 20 chr12:109029347-10902936 1.0000 20 chr6:45798509-45798529 1.0000 20 chr13:60308760-60308780 1.0000 20 chr20:48237152-48237172 1.0000 20 chr17:38023434-38023454 1.0000 20 chr9:140013416-140013436 1.0000 20 chr4:9814861-9814881 1.0000 20 chr19:6601728-6601748 1.0000 20 chr1:168994344-168994364 1.0000 20 chr5:171388401-171388421 1.0000 20 chr17:75437792-75437812 1.0000 20 chr14:68410764-68410784 1.0000 20 chr20:48295738-48295758 1.0000 20 chr1:108042179-108042199 1.0000 20 chr8:145159274-145159294 1.0000 20 chr17:76151281-76151301 1.0000 20 chr17:38574331-38574351 1.0000 20 chr17:40808189-40808209 1.0000 20 chr4:42659398-42659418 1.0000 20 chr5:155829617-155829637 1.0000 20 chr7:156715995-156716015 1.0000 20 chr11:72125421-72125441 1.0000 20 chr1:45265503-45265523 1.0000 20 chr1:1677899-1677919 1.0000 20 chr3:101510880-101510900 1.0000 20 chr11:57559821-57559841 1.0000 20 chr6:3027408-3027428 1.0000 20 chr1:76250531-76250551 1.0000 20 chr7:74064537-74064557 1.0000 20 chr7:100184161-100184181 1.0000 20 chr5:78281575-78281595 1.0000 20 chr3:187463403-187463423 1.0000 20 chr5:109031100-109031120 1.0000 20 chr15:63772088-63772108 1.0000 20 chr10:120880092-12088011 1.0000 20 chr3:73500656-73500676 1.0000 20 chr12:129399655-12939967 1.0000 20 chr8:21817711-21817731 1.0000 20 chr3:95106559-95106579 1.0000 20 chr4:144293805-144293825 1.0000 20 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/GM12878/inference_raw/MEME/RankLinear0.6_10_SKIL/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/SKIL.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 5000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 5000 norand= no csites= 1000 Letter frequencies in dataset: A 0.274 C 0.229 G 0.225 T 0.272 Background letter frequencies (from file dataset with add-one prior applied): A 0.274 C 0.229 G 0.225 T 0.272 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF WGWCWGWC MEME-1 width = 8 sites = 31 llr = 206 E-value = 6.1e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif WGWCWGWC MEME-1 Description -------------------------------------------------------------------------------- Simplified A 5:5:5:5: pos.-specific C :::8:118 probability G :a12:912 matrix T 5:5:5:3: bits 2.2 * 1.9 * 1.7 * * 1.5 * * * * Relative 1.3 * * * * Entropy 1.1 * * * * (9.6 bits) 0.9 ** *** * 0.6 ****** * 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGACAGAC consensus A T T T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGWCWGWC MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr10:5894541-5894561 5 2.96e-05 GCGG TGACAGAC TGGGCTGT chr10:82796158-82796178 1 2.96e-05 . TGACAGAC GCTGGGCTGT chr1:38518795-38518815 6 2.96e-05 AATTG TGTCAGAC AGTACTT chr1:202587721-202587741 1 2.96e-05 . tgtcagac ttcttaacta chr1:28496025-28496045 8 8.88e-05 actctgg agtcagac tctgt chr4:103474064-103474084 7 1.18e-04 AACCTC AGTCTGAC ACTTAG chr22:39512206-39512226 4 1.48e-04 tgg tgacagtc tagcacctt chr7:100184161-100184181 4 2.07e-04 GAG TGACTGTC AAGAAGGCC chr4:38807396-38807416 1 2.07e-04 . TGACTGTC TCTCTCTGTT chr9:139894808-139894828 11 2.07e-04 TTTTGCTTCC TGTCTGTC CA chr17:8762635-8762655 4 2.36e-04 ACC AGTCTGTC ACCTCATAA chr1:200875056-200875076 1 2.36e-04 . agactgtc tgggtgtgaa chr9:130795549-130795569 4 2.94e-04 agg tgtgagac accatgtct chr15:70593028-70593048 2 2.94e-04 G TGAGAGAC TCATGGCCGG chr16:19305879-19305899 9 4.10e-04 cctcctac agtcagag aaag chr16:68309712-68309732 12 4.10e-04 TTTTGTGGTC TGTGTGAC A chr3:17193302-17193322 1 4.81e-04 . AGTCTGAG TTTCTCTGAA chr10:85750085-85750105 6 4.81e-04 CCTGG TGGCAGAC AAGGCCT chr17:37914460-37914480 7 4.81e-04 GCTCAT AGACTGAG AACCTG chr12:125166029-12516604 7 4.81e-04 cctaga agagtgac tcaacc chr6:14110392-14110412 8 5.66e-04 ATGAAGG TGACAGCC AGTGG chr2:231122617-231122637 1 6.65e-04 . TGACTGGC GGCCTTCAAA chr2:111432955-111432975 6 6.65e-04 gtgcc agacagcc acgtagc chr15:51177575-51177595 7 7.71e-04 GAGGCA AGTCTGGC ACAGGC chr7:17199268-17199288 9 9.17e-04 GACTTTGC AGACAGTG AGAG chr19:11679240-11679260 5 9.17e-04 TCTG AGTCAGTG AGAAGAGC chr5:33848825-33848845 10 9.17e-04 GAAGTATTT TGAGTGTC TAT chr18:47485739-47485759 9 1.05e-03 ATCACAGG AGTCACAC CTCT chr2:68441704-68441724 12 1.05e-03 aattagatac tgtctcac a chr9:71770417-71770437 3 1.10e-03 tc aggcagtc tggggtaagt chr18:56209115-56209135 7 1.10e-03 AACCAC AGACTCAC ACCTTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGWCWGWC MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:5894541-5894561 3e-05 4_[+1]_8 chr10:82796158-82796178 3e-05 [+1]_12 chr1:38518795-38518815 3e-05 5_[+1]_7 chr1:202587721-202587741 3e-05 [+1]_12 chr1:28496025-28496045 8.9e-05 7_[+1]_5 chr4:103474064-103474084 0.00012 6_[+1]_6 chr22:39512206-39512226 0.00015 3_[+1]_9 chr7:100184161-100184181 0.00021 3_[+1]_9 chr4:38807396-38807416 0.00021 [+1]_12 chr9:139894808-139894828 0.00021 10_[+1]_2 chr17:8762635-8762655 0.00024 3_[+1]_9 chr1:200875056-200875076 0.00024 [+1]_12 chr9:130795549-130795569 0.00029 3_[+1]_9 chr15:70593028-70593048 0.00029 1_[+1]_11 chr16:19305879-19305899 0.00041 8_[+1]_4 chr16:68309712-68309732 0.00041 11_[+1]_1 chr3:17193302-17193322 0.00048 [+1]_12 chr10:85750085-85750105 0.00048 5_[+1]_7 chr17:37914460-37914480 0.00048 6_[+1]_6 chr12:125166029-12516604 0.00048 6_[+1]_6 chr6:14110392-14110412 0.00057 7_[+1]_5 chr2:231122617-231122637 0.00066 [+1]_12 chr2:111432955-111432975 0.00066 5_[+1]_7 chr15:51177575-51177595 0.00077 6_[+1]_6 chr7:17199268-17199288 0.00092 8_[+1]_4 chr19:11679240-11679260 0.00092 4_[+1]_8 chr5:33848825-33848845 0.00092 9_[+1]_3 chr18:47485739-47485759 0.001 8_[+1]_4 chr2:68441704-68441724 0.001 11_[+1]_1 chr9:71770417-71770437 0.0011 2_[+1]_10 chr18:56209115-56209135 0.0011 6_[+1]_6 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGWCWGWC MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WGWCWGWC width=8 seqs=31 chr10:5894541-5894561 ( 5) TGACAGAC 1 chr10:82796158-82796178 ( 1) TGACAGAC 1 chr1:38518795-38518815 ( 6) TGTCAGAC 1 chr1:202587721-202587741 ( 1) TGTCAGAC 1 chr1:28496025-28496045 ( 8) AGTCAGAC 1 chr4:103474064-103474084 ( 7) AGTCTGAC 1 chr22:39512206-39512226 ( 4) TGACAGTC 1 chr7:100184161-100184181 ( 4) TGACTGTC 1 chr4:38807396-38807416 ( 1) TGACTGTC 1 chr9:139894808-139894828 ( 11) TGTCTGTC 1 chr17:8762635-8762655 ( 4) AGTCTGTC 1 chr1:200875056-200875076 ( 1) AGACTGTC 1 chr9:130795549-130795569 ( 4) TGTGAGAC 1 chr15:70593028-70593048 ( 2) TGAGAGAC 1 chr16:19305879-19305899 ( 9) AGTCAGAG 1 chr16:68309712-68309732 ( 12) TGTGTGAC 1 chr3:17193302-17193322 ( 1) AGTCTGAG 1 chr10:85750085-85750105 ( 6) TGGCAGAC 1 chr17:37914460-37914480 ( 7) AGACTGAG 1 chr12:125166029-12516604 ( 7) AGAGTGAC 1 chr6:14110392-14110412 ( 8) TGACAGCC 1 chr2:231122617-231122637 ( 1) TGACTGGC 1 chr2:111432955-111432975 ( 6) AGACAGCC 1 chr15:51177575-51177595 ( 7) AGTCTGGC 1 chr7:17199268-17199288 ( 9) AGACAGTG 1 chr19:11679240-11679260 ( 5) AGTCAGTG 1 chr5:33848825-33848845 ( 10) TGAGTGTC 1 chr18:47485739-47485759 ( 9) AGTCACAC 1 chr2:68441704-68441724 ( 12) TGTCTCAC 1 chr9:71770417-71770437 ( 3) AGGCAGTC 1 chr18:56209115-56209135 ( 7) AGACTCAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGWCWGWC MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.00527 E= 6.1e+000 82 -1160 -1160 92 -1160 -1160 215 -1160 82 -1160 -180 73 -1160 187 -48 -1160 91 -1160 -1160 83 -1160 -124 201 -1160 100 -182 -180 24 -1160 187 -48 -1160 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGWCWGWC MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 31 E= 6.1e+000 0.483871 0.000000 0.000000 0.516129 0.000000 0.000000 1.000000 0.000000 0.483871 0.000000 0.064516 0.451613 0.000000 0.838710 0.161290 0.000000 0.516129 0.000000 0.000000 0.483871 0.000000 0.096774 0.903226 0.000000 0.548387 0.064516 0.064516 0.322581 0.000000 0.838710 0.161290 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGWCWGWC MEME-1 regular expression -------------------------------------------------------------------------------- [TA]G[AT]C[AT]G[AT]C -------------------------------------------------------------------------------- Time 5.09 secs. ******************************************************************************** ******************************************************************************** MOTIF CCCWGGSC MEME-2 width = 8 sites = 15 llr = 121 E-value = 9.0e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCCWGGSC MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::5:21: pos.-specific C 8aa:::56 probability G ::::a841 matrix T 2::5:::3 bits 2.2 ** * 1.9 ** * 1.7 ** * 1.5 ** * Relative 1.3 *** ** Entropy 1.1 *** ** (11.6 bits) 0.9 ******* 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CCCAGGCC consensus T T AGT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCWGGSC MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr6:15023859-15023879 13 8.74e-06 GAAGTTCCAT CCCAggcc chr16:48570382-48570402 10 8.74e-06 CAGGGCCTG CCCAGGCC TGA chr21:46898228-46898248 8 2.60e-05 TTGCACA CCCAGGGC GACCC chr19:51847944-51847964 13 4.49e-05 TGACTGTAGA CCCAGGCT chr19:43017164-43017184 1 5.52e-05 . CCCTGGCT TTTCTGCGCT chr9:94909745-94909765 10 5.52e-05 TCCACGCTC CCCTGGCT AGA chr1:45265503-45265523 3 9.45e-05 CT TCCAGGCC CTAAAGAGGG chr17:76151281-76151301 11 1.05e-04 caaaaatgtc cccagacc ca chr6:73359501-73359521 7 1.53e-04 ATCCAA CCCTGACC ACCAAT chr1:246064521-246064541 6 1.53e-04 TAAGT CCCAGGGG TAAGTCC chr22:18589781-18589801 4 1.53e-04 aga cccagggg agctgaaga chr13:30333019-30333039 9 1.82e-04 aggggatg tcctgggc ccac chr19:6577623-6577643 1 1.92e-04 . CCCTGAGC GGATGAGACA chr17:70418925-70418945 13 2.26e-04 CCACAGAGCC CCCTGGAC chr3:95106559-95106579 2 3.00e-04 t tcctgggt tgctgcagct -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCWGGSC MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:15023859-15023879 8.7e-06 12_[+2] chr16:48570382-48570402 8.7e-06 9_[+2]_3 chr21:46898228-46898248 2.6e-05 7_[+2]_5 chr19:51847944-51847964 4.5e-05 12_[+2] chr19:43017164-43017184 5.5e-05 [+2]_12 chr9:94909745-94909765 5.5e-05 9_[+2]_3 chr1:45265503-45265523 9.4e-05 2_[+2]_10 chr17:76151281-76151301 0.00011 10_[+2]_2 chr6:73359501-73359521 0.00015 6_[+2]_6 chr1:246064521-246064541 0.00015 5_[+2]_7 chr22:18589781-18589801 0.00015 3_[+2]_9 chr13:30333019-30333039 0.00018 8_[+2]_4 chr19:6577623-6577643 0.00019 [+2]_12 chr17:70418925-70418945 0.00023 12_[+2] chr3:95106559-95106579 0.0003 1_[+2]_11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCWGGSC MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCCWGGSC width=8 seqs=15 chr6:15023859-15023879 ( 13) CCCAGGCC 1 chr16:48570382-48570402 ( 10) CCCAGGCC 1 chr21:46898228-46898248 ( 8) CCCAGGGC 1 chr19:51847944-51847964 ( 13) CCCAGGCT 1 chr19:43017164-43017184 ( 1) CCCTGGCT 1 chr9:94909745-94909765 ( 10) CCCTGGCT 1 chr1:45265503-45265523 ( 3) TCCAGGCC 1 chr17:76151281-76151301 ( 11) CCCAGACC 1 chr6:73359501-73359521 ( 7) CCCTGACC 1 chr1:246064521-246064541 ( 6) CCCAGGGG 1 chr22:18589781-18589801 ( 4) CCCAGGGG 1 chr13:30333019-30333039 ( 9) TCCTGGGC 1 chr19:6577623-6577643 ( 1) CCCTGAGC 1 chr17:70418925-70418945 ( 13) CCCTGGAC 1 chr3:95106559-95106579 ( 2) TCCTGGGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCWGGSC MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 9.0312 E= 9.0e+001 -1055 181 -1055 -45 -1055 213 -1055 -1055 -1055 213 -1055 -1055 96 -1055 -1055 78 -1055 -1055 215 -1055 -46 -1055 183 -1055 -204 122 83 -1055 -1055 139 -75 -3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCWGGSC MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 15 E= 9.0e+001 0.000000 0.800000 0.000000 0.200000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.533333 0.000000 0.000000 0.466667 0.000000 0.000000 1.000000 0.000000 0.200000 0.000000 0.800000 0.000000 0.066667 0.533333 0.400000 0.000000 0.000000 0.600000 0.133333 0.266667 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCWGGSC MEME-2 regular expression -------------------------------------------------------------------------------- [CT]CC[AT]G[GA][CG][CT] -------------------------------------------------------------------------------- Time 8.10 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTCTYTY MEME-3 width = 8 sites = 34 llr = 215 E-value = 8.1e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTCTYTY MEME-3 Description -------------------------------------------------------------------------------- Simplified A :::::1:: pos.-specific C :::8:224 probability G ::32:222 matrix T aa7:a464 bits 2.2 1.9 * * 1.7 ** * 1.5 ** * Relative 1.3 ** ** Entropy 1.1 ***** (9.1 bits) 0.9 ***** 0.6 ***** * 0.4 ***** ** 0.2 ******** 0.0 -------- Multilevel TTTCTTTT consensus GG CGC sequence GCG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCTYTY MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr10:121468593-12146861 13 4.65e-05 ACAGAAATAG TTTCTTTC chr1:210638210-210638230 7 4.65e-05 AGAAAG TTTCTTTC TGAGTC chr1:79086037-79086057 2 4.65e-05 C TTTCTTTC TCTTCCTAGT chr19:14779165-14779185 11 8.56e-05 ACTTTTTTTT TTTCTCTT AG chr19:50850712-50850732 8 8.56e-05 gggtctc tttctctc ttctc chr10:120880092-12088011 7 1.45e-04 CTGAAG TTTCTGTT TAGCTC chr2:120110174-120110194 3 1.45e-04 gt tttctgtc tataaatacc chr14:81053801-81053821 12 1.45e-04 TACTCATGTT Tttctttg a chr3:184925888-184925908 7 1.83e-04 tcatac tttcttgc cctctc chr4:144293805-144293825 13 2.61e-04 gaggtcatgt ttgctttc chr3:17193302-17193322 9 2.78e-04 AGTCTGAG TTTCTCTG AATC chr5:109031100-109031120 11 3.74e-04 ACCACTTTTA TTTGTTTT TG chr1:108042179-108042199 11 3.74e-04 GTATTTCACT TTTGTTTT AT chr20:3888246-3888266 7 3.74e-04 TGAATC TTTGTTTT TCACAG chr7:129045499-129045519 13 4.23e-04 tctagcaggt tttctggt chr9:35634676-35634696 10 5.35e-04 TTCCCTTCC TTTCTCCC ATT chr8:126123230-126123250 9 5.35e-04 TCTCATGT TTGCTCTT CTTT chr9:132751529-132751549 11 6.34e-04 GCAGTTCTGT TTTCTGCT GT chr5:155829617-155829637 6 6.66e-04 tctac ttgcttgt tcataca chr11:95785238-95785258 6 6.66e-04 CTGTA TTGCTTGC AAAATGC chr1:110786432-110786452 12 8.09e-04 CCCCAAACGC TTTGTTTG G chr9:139894808-139894828 3 8.09e-04 TT TTGCTTCC TGTCTGTCCA chr9:129770157-129770177 11 9.12e-04 cttacaagga ttgctctg gc chr7:23408110-23408130 11 9.12e-04 agattagtgg tttctatg gg chr5:78281575-78281595 4 1.08e-03 TCA TTTCTAGC ACAAGAGCC chr11:57559821-57559841 11 1.08e-03 TCCTCTGGTT TTTCTAGT CT chr19:43017164-43017184 9 1.08e-03 CCCTGGCT TTTCTGCG CTCA chr7:41849997-41850017 1 1.08e-03 . TTTGTTCT CAGCCTTCTA chr17:38023434-38023454 8 1.25e-03 ACAAAGT TTGCTCCT GGACC chr15:63772088-63772108 3 1.38e-03 CA TTTGTGGT TGCAAGAATG chr16:68309712-68309732 3 1.38e-03 GT TTTGTGGT CTGTGTGACA chr8:59080397-59080417 5 1.71e-03 AAAC TTGCTATG AATGTTTT chr1:1677899-1677919 10 1.80e-03 GGCAGCCCG TTGGTTCC GCC chr16:12058937-12058957 10 2.31e-03 TTTACACCC TGTCTCTT ACC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCTYTY MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:121468593-12146861 4.6e-05 12_[+3] chr1:210638210-210638230 4.6e-05 6_[+3]_6 chr1:79086037-79086057 4.6e-05 1_[+3]_11 chr19:14779165-14779185 8.6e-05 10_[+3]_2 chr19:50850712-50850732 8.6e-05 7_[+3]_5 chr10:120880092-12088011 0.00014 6_[+3]_6 chr2:120110174-120110194 0.00014 2_[+3]_10 chr14:81053801-81053821 0.00014 11_[+3]_1 chr3:184925888-184925908 0.00018 6_[+3]_6 chr4:144293805-144293825 0.00026 12_[+3] chr3:17193302-17193322 0.00028 8_[+3]_4 chr5:109031100-109031120 0.00037 10_[+3]_2 chr1:108042179-108042199 0.00037 10_[+3]_2 chr20:3888246-3888266 0.00037 6_[+3]_6 chr7:129045499-129045519 0.00042 12_[+3] chr9:35634676-35634696 0.00053 9_[+3]_3 chr8:126123230-126123250 0.00053 8_[+3]_4 chr9:132751529-132751549 0.00063 10_[+3]_2 chr5:155829617-155829637 0.00067 5_[+3]_7 chr11:95785238-95785258 0.00067 5_[+3]_7 chr1:110786432-110786452 0.00081 11_[+3]_1 chr9:139894808-139894828 0.00081 2_[+3]_10 chr9:129770157-129770177 0.00091 10_[+3]_2 chr7:23408110-23408130 0.00091 10_[+3]_2 chr5:78281575-78281595 0.0011 3_[+3]_9 chr11:57559821-57559841 0.0011 10_[+3]_2 chr19:43017164-43017184 0.0011 8_[+3]_4 chr7:41849997-41850017 0.0011 [+3]_12 chr17:38023434-38023454 0.0012 7_[+3]_5 chr15:63772088-63772108 0.0014 2_[+3]_10 chr16:68309712-68309732 0.0014 2_[+3]_10 chr8:59080397-59080417 0.0017 4_[+3]_8 chr1:1677899-1677919 0.0018 9_[+3]_3 chr16:12058937-12058957 0.0023 9_[+3]_3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCTYTY MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTCTYTY width=8 seqs=34 chr10:121468593-12146861 ( 13) TTTCTTTC 1 chr1:210638210-210638230 ( 7) TTTCTTTC 1 chr1:79086037-79086057 ( 2) TTTCTTTC 1 chr19:14779165-14779185 ( 11) TTTCTCTT 1 chr19:50850712-50850732 ( 8) TTTCTCTC 1 chr10:120880092-12088011 ( 7) TTTCTGTT 1 chr2:120110174-120110194 ( 3) TTTCTGTC 1 chr14:81053801-81053821 ( 12) TTTCTTTG 1 chr3:184925888-184925908 ( 7) TTTCTTGC 1 chr4:144293805-144293825 ( 13) TTGCTTTC 1 chr3:17193302-17193322 ( 9) TTTCTCTG 1 chr5:109031100-109031120 ( 11) TTTGTTTT 1 chr1:108042179-108042199 ( 11) TTTGTTTT 1 chr20:3888246-3888266 ( 7) TTTGTTTT 1 chr7:129045499-129045519 ( 13) TTTCTGGT 1 chr9:35634676-35634696 ( 10) TTTCTCCC 1 chr8:126123230-126123250 ( 9) TTGCTCTT 1 chr9:132751529-132751549 ( 11) TTTCTGCT 1 chr5:155829617-155829637 ( 6) TTGCTTGT 1 chr11:95785238-95785258 ( 6) TTGCTTGC 1 chr1:110786432-110786452 ( 12) TTTGTTTG 1 chr9:139894808-139894828 ( 3) TTGCTTCC 1 chr9:129770157-129770177 ( 11) TTGCTCTG 1 chr7:23408110-23408130 ( 11) TTTCTATG 1 chr5:78281575-78281595 ( 4) TTTCTAGC 1 chr11:57559821-57559841 ( 11) TTTCTAGT 1 chr19:43017164-43017184 ( 9) TTTCTGCG 1 chr7:41849997-41850017 ( 1) TTTGTTCT 1 chr17:38023434-38023454 ( 8) TTGCTCCT 1 chr15:63772088-63772108 ( 3) TTTGTGGT 1 chr16:68309712-68309732 ( 3) TTTGTGGT 1 chr8:59080397-59080417 ( 5) TTGCTATG 1 chr1:1677899-1677919 ( 10) TTGGTTCC 1 chr16:12058937-12058957 ( 10) TGTCTCTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCTYTY MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 7.36472 E= 8.1e+002 -1173 -1173 -1173 188 -1173 -1173 -293 183 -1173 -1173 24 143 -1173 174 7 -1173 -1173 -1173 -1173 188 -122 4 -13 70 -1173 -15 7 104 -1173 63 -13 70 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCTYTY MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 34 E= 8.1e+002 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.029412 0.970588 0.000000 0.000000 0.264706 0.735294 0.000000 0.764706 0.235294 0.000000 0.000000 0.000000 0.000000 1.000000 0.117647 0.235294 0.205882 0.441176 0.000000 0.205882 0.235294 0.558824 0.000000 0.352941 0.205882 0.441176 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTCTYTY MEME-3 regular expression -------------------------------------------------------------------------------- TT[TG][CG]T[TCG][TGC][TCG] -------------------------------------------------------------------------------- Time 10.77 secs. ******************************************************************************** ******************************************************************************** MOTIF TTKARAAA MEME-4 width = 8 sites = 12 llr = 100 E-value = 5.5e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTKARAAA MEME-4 Description -------------------------------------------------------------------------------- Simplified A :2:a4aa9 pos.-specific C ::::1::: probability G ::7:5::1 matrix T a83::::: bits 2.2 1.9 * * ** 1.7 * * ** 1.5 * * *** Relative 1.3 ** * *** Entropy 1.1 **** *** (12.0 bits) 0.9 **** *** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TTGAGAAA consensus T A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKARAAA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:59043980-59044000 8 2.11e-05 TGAGTCA TTGAGAAA GTCTA chr5:114545123-114545143 5 2.11e-05 GTAG TTGAGAAA CTGTGGGC chr12:26901794-26901814 11 4.68e-05 GAAGCCAGAA TTGAAAAA CC chr20:5655019-5655039 1 4.68e-05 . ttgaaaaa ccacacagca chrX:122918797-122918817 3 7.23e-05 at tttagaaa gatagagttt chr7:101577088-101577108 13 1.03e-04 TAACCAGACA TTTAAAAA chr18:77196084-77196104 2 1.03e-04 A TTTAAAAA CAAACGAGAA chr17:44233408-44233428 6 1.03e-04 AGTAG TTTAAAAA TATGCAG chr20:45903440-45903460 13 1.25e-04 GAATCAGAAC TAGAGAAA chr19:47690117-47690137 4 1.25e-04 TTC TAGAGAAA GACATGAAA chr6:32995789-32995809 3 1.46e-04 TT TTGACAAA TGTGGTACCT chr7:104909663-104909683 12 1.89e-04 ACTAGATAAT TTGAGAAG C -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKARAAA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:59043980-59044000 2.1e-05 7_[+4]_5 chr5:114545123-114545143 2.1e-05 4_[+4]_8 chr12:26901794-26901814 4.7e-05 10_[+4]_2 chr20:5655019-5655039 4.7e-05 [+4]_12 chrX:122918797-122918817 7.2e-05 2_[+4]_10 chr7:101577088-101577108 0.0001 12_[+4] chr18:77196084-77196104 0.0001 1_[+4]_11 chr17:44233408-44233428 0.0001 5_[+4]_7 chr20:45903440-45903460 0.00012 12_[+4] chr19:47690117-47690137 0.00012 3_[+4]_9 chr6:32995789-32995809 0.00015 2_[+4]_10 chr7:104909663-104909683 0.00019 11_[+4]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKARAAA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTKARAAA width=8 seqs=12 chr1:59043980-59044000 ( 8) TTGAGAAA 1 chr5:114545123-114545143 ( 5) TTGAGAAA 1 chr12:26901794-26901814 ( 11) TTGAAAAA 1 chr20:5655019-5655039 ( 1) TTGAAAAA 1 chrX:122918797-122918817 ( 3) TTTAGAAA 1 chr7:101577088-101577108 ( 13) TTTAAAAA 1 chr18:77196084-77196104 ( 2) TTTAAAAA 1 chr17:44233408-44233428 ( 6) TTTAAAAA 1 chr20:45903440-45903460 ( 13) TAGAGAAA 1 chr19:47690117-47690137 ( 4) TAGAGAAA 1 chr6:32995789-32995809 ( 3) TTGACAAA 1 chr7:104909663-104909683 ( 12) TTGAGAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKARAAA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.52481 E= 5.5e+002 -1023 -1023 -1023 188 -72 -1023 -1023 161 -1023 -1023 157 29 186 -1023 -1023 -1023 60 -145 115 -1023 186 -1023 -1023 -1023 186 -1023 -1023 -1023 174 -1023 -143 -1023 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKARAAA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 12 E= 5.5e+002 0.000000 0.000000 0.000000 1.000000 0.166667 0.000000 0.000000 0.833333 0.000000 0.000000 0.666667 0.333333 1.000000 0.000000 0.000000 0.000000 0.416667 0.083333 0.500000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.916667 0.000000 0.083333 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTKARAAA MEME-4 regular expression -------------------------------------------------------------------------------- TT[GT]A[GA]AAA -------------------------------------------------------------------------------- Time 11.51 secs. ******************************************************************************** ******************************************************************************** MOTIF WGKGGTGA MEME-5 width = 8 sites = 6 llr = 59 E-value = 4.4e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif WGKGGTGA MEME-5 Description -------------------------------------------------------------------------------- Simplified A 5::::::a pos.-specific C :::::::: probability G :a3aa:a: matrix T 5:7::a:: bits 2.2 * ** * 1.9 * ***** 1.7 * ***** 1.5 * ***** Relative 1.3 * ***** Entropy 1.1 ******* (14.3 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AGTGGTGA consensus T G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGKGGTGA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:9913622-9913642 13 2.84e-05 AGTGTGTTGT TGTGGTGA chr1:181121275-181121295 10 2.84e-05 cagagttgc agtggtga atc chr22:43773035-43773055 5 2.84e-05 GCAG TGTGGTGA GGTTCACA chr12:112211934-11221195 12 2.84e-05 CCATCTTTGA AGTGGTGA A chr1:25346069-25346089 9 5.18e-05 GACACCTG TGGGGTGA GCAC chr1:200849594-200849614 8 5.18e-05 CTAGACA AGGGGTGA TTAAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGKGGTGA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:9913622-9913642 2.8e-05 12_[+5] chr1:181121275-181121295 2.8e-05 9_[+5]_3 chr22:43773035-43773055 2.8e-05 4_[+5]_8 chr12:112211934-11221195 2.8e-05 11_[+5]_1 chr1:25346069-25346089 5.2e-05 8_[+5]_4 chr1:200849594-200849614 5.2e-05 7_[+5]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGKGGTGA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF WGKGGTGA width=8 seqs=6 chr12:9913622-9913642 ( 13) TGTGGTGA 1 chr1:181121275-181121295 ( 10) AGTGGTGA 1 chr22:43773035-43773055 ( 5) TGTGGTGA 1 chr12:112211934-11221195 ( 12) AGTGGTGA 1 chr1:25346069-25346089 ( 9) TGGGGTGA 1 chr1:200849594-200849614 ( 8) AGGGGTGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGKGGTGA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 7.85264 E= 4.4e+002 86 -923 -923 88 -923 -923 215 -923 -923 -923 57 129 -923 -923 215 -923 -923 -923 215 -923 -923 -923 -923 187 -923 -923 215 -923 186 -923 -923 -923 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGKGGTGA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 6 E= 4.4e+002 0.500000 0.000000 0.000000 0.500000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.333333 0.666667 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif WGKGGTGA MEME-5 regular expression -------------------------------------------------------------------------------- [AT]G[TG]GGTGA -------------------------------------------------------------------------------- Time 12.18 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:129045499-129045519 7.01e-02 20 chr15:70593028-70593048 1.04e-02 20 chr1:119682206-119682226 4.25e-01 20 chr1:79086037-79086057 5.93e-02 1_[+3(4.65e-05)]_11 chr2:11244394-11244414 5.83e-01 20 chr4:103474064-103474084 6.84e-02 20 chr13:113840769-11384078 3.33e-01 20 chr2:68441704-68441724 8.93e-02 20 chr19:51847944-51847964 8.56e-03 12_[+2(4.49e-05)] chr10:86090181-86090201 9.84e-01 20 chr1:200875056-200875076 1.69e-03 20 chr9:139894808-139894828 2.60e-03 20 chr19:50844521-50844541 4.45e-01 20 chr2:47729914-47729934 4.71e-02 20 chr3:122252865-122252885 2.39e-01 20 chr1:207588036-207588056 8.68e-01 20 chr22:20023837-20023857 6.73e-01 20 chr2:47924570-47924590 9.15e-02 20 chr11:107415986-10741600 7.17e-01 20 chr4:26320786-26320806 5.95e-01 20 chr1:161065985-161066005 9.78e-01 20 chr18:47485739-47485759 6.57e-02 20 chr8:120055688-120055708 5.90e-01 20 chr2:234428963-234428983 6.44e-01 20 chr7:41849997-41850017 7.96e-02 20 chr2:208014769-208014789 5.50e-01 20 chr7:23408110-23408130 7.67e-02 20 chr1:202587721-202587741 3.63e-02 [+1(2.96e-05)]_12 chr2:113394307-113394327 4.42e-01 20 chr6:14110392-14110412 7.51e-02 20 chr3:146221684-146221704 8.11e-01 20 chr15:101675925-10167594 4.30e-01 20 chr13:30333019-30333039 6.24e-02 20 chr12:112211934-11221195 1.81e-02 11_[+5(2.84e-05)]_1 chr6:36325832-36325852 1.47e-01 20 chr1:110786432-110786452 1.45e-01 20 chr22:40607002-40607022 1.55e-01 20 chr2:120188750-120188770 2.89e-02 20 chr1:66863064-66863084 1.21e-01 20 chr22:39512206-39512226 5.38e-02 20 chr2:111432955-111432975 2.26e-01 20 chr1:38518795-38518815 1.11e-02 5_[+1(2.96e-05)]_7 chr7:2393994-2394014 3.79e-01 20 chr6:64093925-64093945 9.22e-01 20 chr21:46898228-46898248 8.81e-03 7_[+2(2.60e-05)]_5 chr8:126123230-126123250 3.22e-01 20 chr19:47690117-47690137 1.37e-02 20 chr7:114556794-114556814 1.32e-01 20 chr11:60529076-60529096 2.01e-01 20 chr10:116286040-11628606 9.91e-01 20 chr12:96769764-96769784 3.47e-01 20 chr11:329603-329623 7.93e-01 20 chr12:104976771-10497679 4.72e-01 20 chr1:222013331-222013351 9.61e-01 20 chr14:94478328-94478348 9.09e-01 20 chr5:33848825-33848845 1.06e-01 20 chr11:67886757-67886777 6.78e-01 20 chr12:125166029-12516604 1.00e-02 20 chr1:210638210-210638230 7.75e-03 6_[+3(4.65e-05)]_6 chr9:94909745-94909765 3.53e-02 9_[+2(5.52e-05)]_3 chr22:43773035-43773055 1.81e-02 4_[+5(2.84e-05)]_8 chr11:128666315-12866633 7.29e-01 20 chr1:221967145-221967165 1.94e-01 20 chr2:102371976-102371996 2.66e-01 20 chr10:121255989-12125600 8.51e-01 20 chr9:129770157-129770177 5.26e-02 20 chr7:99942668-99942688 5.66e-02 20 chr1:200849594-200849614 1.01e-03 7_[+5(5.18e-05)]_5 chr17:37914460-37914480 6.65e-02 20 chr6:58313044-58313064 5.59e-01 20 chr1:221917237-221917257 1.09e-01 20 chr8:59080397-59080417 1.82e-01 20 chr1:43663566-43663586 2.94e-01 20 chr1:28496025-28496045 8.89e-03 7_[+1(8.88e-05)]_5 chr2:242672087-242672107 1.45e-01 20 chr6:130835072-130835092 2.10e-01 20 chr11:119622589-11962260 2.76e-01 20 chr20:3888246-3888266 1.18e-01 20 chr1:183658989-183659009 1.03e-01 20 chr10:82796158-82796178 7.85e-04 [+1(2.96e-05)]_12 chr14:50387836-50387856 6.70e-01 20 chr2:232537346-232537366 5.76e-01 20 chr9:35634676-35634696 1.34e-01 20 chr16:48570382-48570402 7.21e-03 9_[+2(8.74e-06)]_3 chrX:47880843-47880863 3.08e-01 20 chr1:8537475-8537495 5.38e-01 20 chr17:44233408-44233428 1.17e-01 20 chr20:5655019-5655039 5.14e-02 [+4(4.68e-05)]_12 chr9:130795549-130795569 2.92e-03 20 chr18:56209115-56209135 1.61e-01 20 chr1:94081586-94081606 6.82e-01 20 chr5:114545123-114545143 1.05e-03 4_[+4(2.11e-05)]_8 chr14:81053801-81053821 1.38e-01 20 chr2:118813256-118813276 2.46e-01 20 chr15:51177575-51177595 1.84e-01 20 chr11:63399133-63399153 3.44e-01 20 chr7:86945774-86945794 5.66e-01 20 chr12:92987829-92987849 1.20e-01 20 chr6:150958173-150958193 4.66e-02 20 chr1:185287113-185287133 7.26e-01 20 chr7:92260761-92260781 3.77e-01 20 chr20:56293615-56293635 1.97e-01 20 chr9:71770417-71770437 1.40e-02 20 chr2:223316152-223316172 5.67e-01 20 chr17:1987136-1987156 6.43e-01 20 chr1:157566370-157566390 1.82e-01 20 chr17:33668815-33668835 8.45e-01 20 chr3:170070892-170070912 6.63e-01 20 chr12:82062502-82062522 3.34e-01 20 chr20:45903440-45903460 5.12e-02 20 chr11:121238317-12123833 4.79e-01 20 chr3:10265593-10265613 5.55e-01 20 chrX:122918797-122918817 4.71e-02 2_[+4(7.23e-05)]_10 chr18:77196084-77196104 9.96e-02 20 chr2:135810193-135810213 1.96e-01 20 chr11:77342260-77342280 5.00e-01 20 chr1:2231947-2231967 2.10e-01 20 chr19:18949812-18949832 9.54e-01 20 chr4:151892170-151892190 6.72e-01 20 chr1:39991716-39991736 1.66e-01 20 chr12:26901794-26901814 1.03e-02 10_[+4(4.68e-05)]_2 chr13:76112102-76112122 3.76e-01 20 chr1:25346069-25346089 1.48e-02 8_[+5(5.18e-05)]_4 chr7:44673342-44673362 5.14e-01 20 chr10:121468593-12146861 2.58e-02 12_[+3(4.65e-05)] chr7:8008142-8008162 3.52e-01 20 chr19:11679240-11679260 4.12e-02 20 chr22:18589781-18589801 2.62e-02 20 chr16:68309712-68309732 3.90e-03 20 chr15:64303128-64303148 6.22e-01 20 chr5:173345063-173345083 6.94e-01 20 chr3:12437266-12437286 2.43e-01 20 chr3:15598215-15598235 1.79e-01 20 chr1:174938014-174938034 6.14e-02 20 chr17:7589761-7589781 7.57e-01 20 chr19:13010878-13010898 1.36e-01 20 chr10:85750085-85750105 6.33e-03 20 chr17:34136231-34136251 6.97e-01 20 chr19:6577623-6577643 3.43e-03 20 chr22:42000110-42000130 9.76e-01 20 chr11:44631134-44631154 4.91e-01 20 chr7:104909663-104909683 6.30e-02 20 chr2:120110174-120110194 5.64e-03 20 chr17:8762635-8762655 7.35e-02 20 chr12:27437956-27437976 2.92e-01 20 chr2:231122617-231122637 1.25e-02 20 chr19:50850712-50850732 7.48e-02 7_[+3(8.56e-05)]_5 chr18:13612442-13612462 6.92e-02 20 chr1:181121275-181121295 7.38e-03 9_[+5(2.84e-05)]_3 chr12:106696439-10669645 2.33e-01 20 chr19:10382376-10382396 5.84e-02 20 chr12:9913622-9913642 3.60e-03 12_[+5(2.84e-05)] chr20:2083121-2083141 2.82e-02 20 chr3:184925888-184925908 1.05e-01 20 chrX:70839188-70839208 6.57e-01 20 chr16:19305879-19305899 3.60e-02 20 chr6:15023859-15023879 2.09e-02 12_[+2(8.74e-06)] chr1:246064521-246064541 6.95e-03 20 chr16:12058937-12058957 3.07e-02 20 chr1:208108665-208108685 7.06e-01 20 chr21:16250239-16250259 8.48e-01 20 chr11:85959803-85959823 5.24e-01 20 chr15:80348490-80348510 9.07e-02 20 chr7:87104245-87104265 3.71e-01 20 chr16:10870320-10870340 4.02e-01 20 chr17:70418925-70418945 1.43e-01 20 chr19:7894883-7894903 9.58e-01 20 chr11:95785238-95785258 2.01e-02 20 chr6:90544935-90544955 7.70e-01 20 chr2:71588962-71588982 7.36e-01 20 chr4:38807396-38807416 3.21e-02 20 chr9:116282660-116282680 7.64e-01 20 chr19:14779165-14779185 1.58e-01 10_[+3(8.56e-05)]_2 chr11:65905323-65905343 8.33e-01 20 chr19:43017164-43017184 1.77e-03 [+2(5.52e-05)]_12 chr6:73359501-73359521 1.35e-01 20 chr14:77587910-77587930 9.28e-01 20 chr20:42219390-42219410 6.81e-01 20 chr19:35815313-35815333 5.27e-01 20 chr17:16311831-16311851 7.61e-01 20 chr2:158261073-158261093 7.29e-01 20 chr3:17193302-17193322 3.54e-03 20 chr8:114467352-114467372 8.38e-01 20 chr9:127054125-127054145 9.11e-02 20 chr6:34779185-34779205 5.77e-01 20 chr21:19192111-19192131 9.07e-01 20 chr11:1872357-1872377 2.51e-01 20 chr13:66712671-66712691 5.97e-01 20 chr11:118098731-11809875 4.78e-01 20 chr11:121446074-12144609 1.18e-01 20 chr21:38564465-38564485 2.78e-01 20 chr16:10391467-10391487 6.34e-01 20 chr6:399967-399987 6.95e-01 20 chr12:48279103-48279123 4.79e-01 20 chr7:87228762-87228782 3.01e-01 20 chr7:101577088-101577108 6.04e-02 20 chr7:17199268-17199288 1.18e-01 20 chr1:87915354-87915374 7.57e-02 20 chr1:59043980-59044000 9.95e-03 7_[+4(2.11e-05)]_5 chr9:132751529-132751549 2.54e-01 20 chr10:5894541-5894561 1.95e-03 4_[+1(2.96e-05)]_8 chr5:142598457-142598477 9.63e-01 20 chr20:50796242-50796262 7.73e-02 20 chr4:90022653-90022673 6.66e-01 20 chr3:45922744-45922764 9.49e-01 20 chr15:45174976-45174996 5.07e-01 20 chr20:56058511-56058531 8.45e-01 20 chr6:32995789-32995809 1.51e-02 20 chr6:114126477-114126497 2.52e-01 20 chr22:22222445-22222465 2.57e-01 20 chr12:109029347-10902936 7.91e-02 20 chr6:45798509-45798529 9.19e-01 20 chr13:60308760-60308780 3.59e-01 20 chr20:48237152-48237172 7.42e-01 20 chr17:38023434-38023454 3.85e-02 20 chr9:140013416-140013436 3.10e-01 20 chr4:9814861-9814881 6.73e-02 20 chr19:6601728-6601748 6.24e-01 20 chr1:168994344-168994364 4.25e-01 20 chr5:171388401-171388421 5.95e-01 20 chr17:75437792-75437812 3.42e-01 20 chr14:68410764-68410784 7.27e-01 20 chr20:48295738-48295758 6.82e-01 20 chr1:108042179-108042199 3.18e-01 20 chr8:145159274-145159294 8.96e-01 20 chr17:76151281-76151301 1.10e-01 20 chr17:38574331-38574351 4.20e-01 20 chr17:40808189-40808209 1.66e-01 20 chr4:42659398-42659418 7.20e-01 20 chr5:155829617-155829637 2.10e-01 20 chr7:156715995-156716015 4.48e-01 20 chr11:72125421-72125441 7.99e-02 20 chr1:45265503-45265523 5.40e-02 2_[+2(9.45e-05)]_10 chr1:1677899-1677919 2.57e-01 20 chr3:101510880-101510900 7.37e-01 20 chr11:57559821-57559841 1.25e-01 20 chr6:3027408-3027428 1.59e-01 20 chr1:76250531-76250551 2.04e-01 20 chr7:74064537-74064557 8.02e-01 20 chr7:100184161-100184181 1.36e-02 20 chr5:78281575-78281595 1.82e-01 20 chr3:187463403-187463423 5.61e-01 20 chr5:109031100-109031120 2.99e-01 20 chr15:63772088-63772108 4.19e-02 20 chr10:120880092-12088011 6.94e-02 20 chr3:73500656-73500676 5.80e-01 20 chr12:129399655-12939967 6.13e-02 20 chr8:21817711-21817731 2.13e-01 20 chr3:95106559-95106579 8.61e-03 20 chr4:144293805-144293825 3.94e-02 20 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n09.farnam.hpc.yale.internal ********************************************************************************