******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/RAD51.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr20:32179935-32179955 1.0000 20 chr4:143488105-143488125 1.0000 20 chr2:158220248-158220268 1.0000 20 chr4:89978360-89978380 1.0000 20 chr17:7236141-7236161 1.0000 20 chr17:6950330-6950350 1.0000 20 chr6:15951401-15951421 1.0000 20 chr15:76027654-76027674 1.0000 20 chr15:78645614-78645634 1.0000 20 chr21:47564027-47564047 1.0000 20 chr2:8820600-8820620 1.0000 20 chr17:79997070-79997090 1.0000 20 chr1:178387898-178387918 1.0000 20 chr22:50972978-50972998 1.0000 20 chr6:14373152-14373172 1.0000 20 chr12:4246387-4246407 1.0000 20 chr19:49284176-49284196 1.0000 20 chr9:74825548-74825568 1.0000 20 chr15:76050870-76050890 1.0000 20 chrX:57259629-57259649 1.0000 20 chr5:72792885-72792905 1.0000 20 chr13:111024687-11102470 1.0000 20 chr13:113695818-11369583 1.0000 20 chr10:14050596-14050616 1.0000 20 chr10:79532829-79532849 1.0000 20 chr12:92879374-92879394 1.0000 20 chr8:102216176-102216196 1.0000 20 chr1:221913149-221913169 1.0000 20 chr8:64082665-64082685 1.0000 20 chr7:158627925-158627945 1.0000 20 chr11:28127673-28127693 1.0000 20 chr3:113473550-113473570 1.0000 20 chr4:176974117-176974137 1.0000 20 chr2:178260517-178260537 1.0000 20 chr2:152683425-152683445 1.0000 20 chr16:10187614-10187634 1.0000 20 chr11:44578572-44578592 1.0000 20 chr20:37971267-37971287 1.0000 20 chr7:5269745-5269765 1.0000 20 chr5:180233740-180233760 1.0000 20 chr15:38546918-38546938 1.0000 20 chr12:46786680-46786700 1.0000 20 chr6:126407899-126407919 1.0000 20 chr3:196647795-196647815 1.0000 20 chr11:17230036-17230056 1.0000 20 chr20:1878351-1878371 1.0000 20 chrX:55744141-55744161 1.0000 20 chr9:76788350-76788370 1.0000 20 chr6:29898002-29898022 1.0000 20 chr9:114987437-114987457 1.0000 20 chr10:103618692-10361871 1.0000 20 chr17:46688395-46688415 1.0000 20 chr14:31733855-31733875 1.0000 20 chr1:180182713-180182733 1.0000 20 chr1:64485693-64485713 1.0000 20 chr16:29832597-29832617 1.0000 20 chrX:24497373-24497393 1.0000 20 chr19:8305390-8305410 1.0000 20 chr4:164471570-164471590 1.0000 20 chr7:1462655-1462675 1.0000 20 chr17:32001881-32001901 1.0000 20 chr3:49028425-49028445 1.0000 20 chrX:101914842-101914862 1.0000 20 chr5:139782383-139782403 1.0000 20 chr16:27760339-27760359 1.0000 20 chr22:42929505-42929525 1.0000 20 chr9:131084491-131084511 1.0000 20 chr19:11487991-11488011 1.0000 20 chr5:142962687-142962707 1.0000 20 chr13:40644655-40644675 1.0000 20 chr1:28195747-28195767 1.0000 20 chr15:34610996-34611016 1.0000 20 chr15:74392578-74392598 1.0000 20 chr4:87935863-87935883 1.0000 20 chr1:1440577-1440597 1.0000 20 chr7:156713328-156713348 1.0000 20 chr11:95524241-95524261 1.0000 20 chr11:64836950-64836970 1.0000 20 chrX:100872984-100873004 1.0000 20 chr10:77162196-77162216 1.0000 20 chr1:111759997-111760017 1.0000 20 chr1:155188825-155188845 1.0000 20 chr2:128588580-128588600 1.0000 20 chr10:69932349-69932369 1.0000 20 chr16:21963936-21963956 1.0000 20 chr14:64212951-64212971 1.0000 20 chr1:226271209-226271229 1.0000 20 chr16:89428877-89428897 1.0000 20 chr1:8229969-8229989 1.0000 20 chr1:220445896-220445916 1.0000 20 chr19:54011581-54011601 1.0000 20 chrX:114797065-114797085 1.0000 20 chr7:116443106-116443126 1.0000 20 chr11:120214330-12021435 1.0000 20 chr12:108662386-10866240 1.0000 20 chr11:63949175-63949195 1.0000 20 chr1:236768123-236768143 1.0000 20 chr10:50396452-50396472 1.0000 20 chr13:30969732-30969752 1.0000 20 chr17:80455121-80455141 1.0000 20 chr6:26196337-26196357 1.0000 20 chr14:72663205-72663225 1.0000 20 chr20:62066327-62066347 1.0000 20 chr19:19600226-19600246 1.0000 20 chr10:70480728-70480748 1.0000 20 chr5:119793710-119793730 1.0000 20 chr2:241526077-241526097 1.0000 20 chr2:130635089-130635109 1.0000 20 chr7:44656975-44656995 1.0000 20 chr11:120197693-12019771 1.0000 20 chr20:570176-570196 1.0000 20 chr20:40321481-40321501 1.0000 20 chr20:32925970-32925990 1.0000 20 chr22:25481954-25481974 1.0000 20 chr2:160470704-160470724 1.0000 20 chr6:42204670-42204690 1.0000 20 chr16:17458433-17458453 1.0000 20 chr4:22741787-22741807 1.0000 20 chr16:11666305-11666325 1.0000 20 chr22:46957591-46957611 1.0000 20 chr16:11457410-11457430 1.0000 20 chr13:98639284-98639304 1.0000 20 chr6:111720941-111720961 1.0000 20 chr19:12099487-12099507 1.0000 20 chr19:49005103-49005123 1.0000 20 chr1:156265472-156265492 1.0000 20 chr10:70883916-70883936 1.0000 20 chr8:126591863-126591883 1.0000 20 chr2:86079367-86079387 1.0000 20 chr15:45076632-45076652 1.0000 20 chr12:31004575-31004595 1.0000 20 chr10:89688893-89688913 1.0000 20 chr2:86088439-86088459 1.0000 20 chr17:46534088-46534108 1.0000 20 chr15:96472646-96472666 1.0000 20 chr22:22523106-22523126 1.0000 20 chr12:112451180-11245120 1.0000 20 chr3:16883532-16883552 1.0000 20 chr15:57324066-57324086 1.0000 20 chr1:169281594-169281614 1.0000 20 chr6:21847113-21847133 1.0000 20 chr15:70551488-70551508 1.0000 20 chr6:39576990-39577010 1.0000 20 chr9:126089143-126089163 1.0000 20 chr12:111028785-11102880 1.0000 20 chr17:38753027-38753047 1.0000 20 chr9:1930555-1930575 1.0000 20 chr1:153934666-153934686 1.0000 20 chr1:6661312-6661332 1.0000 20 chr8:37273983-37274003 1.0000 20 chr14:21148296-21148316 1.0000 20 chr1:1001152-1001172 1.0000 20 chr2:208576122-208576142 1.0000 20 chr4:159726847-159726867 1.0000 20 chr9:5628621-5628641 1.0000 20 chr1:26860626-26860646 1.0000 20 chr20:1103273-1103293 1.0000 20 chr16:68878232-68878252 1.0000 20 chr9:140016536-140016556 1.0000 20 chr7:73707887-73707907 1.0000 20 chr2:37753655-37753675 1.0000 20 chr19:17518319-17518339 1.0000 20 chr17:8762904-8762924 1.0000 20 chr6:47408602-47408622 1.0000 20 chr11:19333457-19333477 1.0000 20 chr8:56832514-56832534 1.0000 20 chr1:90418770-90418790 1.0000 20 chr13:25268462-25268482 1.0000 20 chr6:167364616-167364636 1.0000 20 chr17:72510754-72510774 1.0000 20 chr20:47377024-47377044 1.0000 20 chr4:114001455-114001475 1.0000 20 chr1:173446174-173446194 1.0000 20 chr1:44058791-44058811 1.0000 20 chr9:37719709-37719729 1.0000 20 chr4:36243625-36243645 1.0000 20 chr5:14174638-14174658 1.0000 20 chr14:59743130-59743150 1.0000 20 chr7:116611460-116611480 1.0000 20 chr2:25496374-25496394 1.0000 20 chr16:22229468-22229488 1.0000 20 chr3:15387427-15387447 1.0000 20 chr2:178077438-178077458 1.0000 20 chr11:71814518-71814538 1.0000 20 chr17:63035959-63035979 1.0000 20 chr14:68940729-68940749 1.0000 20 chr6:159495536-159495556 1.0000 20 chr15:44084254-44084274 1.0000 20 chr3:132136288-132136308 1.0000 20 chr2:43449186-43449206 1.0000 20 chr14:105531208-10553122 1.0000 20 chrX:37646099-37646119 1.0000 20 chr2:12074117-12074137 1.0000 20 chr2:178104801-178104821 1.0000 20 chr20:4795810-4795830 1.0000 20 chr21:43953055-43953075 1.0000 20 chr18:21699183-21699203 1.0000 20 chr4:48205573-48205593 1.0000 20 chrX:146993365-146993385 1.0000 20 chr1:2487190-2487210 1.0000 20 chr17:46655745-46655765 1.0000 20 chr11:62538740-62538760 1.0000 20 chr19:50872610-50872630 1.0000 20 chr2:20386445-20386465 1.0000 20 chr17:8095630-8095650 1.0000 20 chr1:11796105-11796125 1.0000 20 chr3:112495127-112495147 1.0000 20 chr7:99942628-99942648 1.0000 20 chr12:92756765-92756785 1.0000 20 chr16:72643979-72643999 1.0000 20 chr10:11916892-11916912 1.0000 20 chr12:96336834-96336854 1.0000 20 chr14:51886591-51886611 1.0000 20 chr7:32930240-32930260 1.0000 20 chr10:134373815-13437383 1.0000 20 chr6:106440463-106440483 1.0000 20 chr3:9695471-9695491 1.0000 20 chr8:42623071-42623091 1.0000 20 chr18:3013566-3013586 1.0000 20 chr10:102756609-10275662 1.0000 20 chr2:231281274-231281294 1.0000 20 chr14:92573098-92573118 1.0000 20 chr1:44440567-44440587 1.0000 20 chr16:15737462-15737482 1.0000 20 chr21:15899686-15899706 1.0000 20 chr3:57678886-57678906 1.0000 20 chr2:118955067-118955087 1.0000 20 chr2:36757618-36757638 1.0000 20 chr8:136537540-136537560 1.0000 20 chr19:47633955-47633975 1.0000 20 chr7:20327026-20327046 1.0000 20 chr14:61905428-61905448 1.0000 20 chr6:41256340-41256360 1.0000 20 chr6:150326481-150326501 1.0000 20 chr17:26372517-26372537 1.0000 20 chr7:22912237-22912257 1.0000 20 chr18:43542624-43542644 1.0000 20 chr1:28559536-28559556 1.0000 20 chr3:156782360-156782380 1.0000 20 chr6:109780284-109780304 1.0000 20 chr22:32072782-32072802 1.0000 20 chr10:46222620-46222640 1.0000 20 chr11:574360-574380 1.0000 20 chr20:5037755-5037775 1.0000 20 chr19:36545323-36545343 1.0000 20 chr2:118761020-118761040 1.0000 20 chr13:80096946-80096966 1.0000 20 chr9:138391741-138391761 1.0000 20 chr1:220621788-220621808 1.0000 20 chr14:106996079-10699609 1.0000 20 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/GM12878/inference_raw/MEME/RankLinear0.6_10_RAD51/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/RAD51.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 5000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 5000 norand= no csites= 1000 Letter frequencies in dataset: A 0.238 C 0.258 G 0.263 T 0.241 Background letter frequencies (from file dataset with add-one prior applied): A 0.238 C 0.258 G 0.263 T 0.241 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TCACGTGA MEME-1 width = 8 sites = 75 llr = 587 E-value = 2.3e-086 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::9:3::8 pos.-specific C 2a17:::: probability G ::::71a2 matrix T 7::3:9:: bits 2.1 1.9 ** * 1.7 ** ** 1.4 ** ** Relative 1.2 ** ** Entropy 1.0 ******* (11.3 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCACGTGA consensus C TA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr9:138391741-138391761 13 1.51e-05 GACGGCCAGG TCACGTGA chr11:574360-574380 6 1.51e-05 tatga tcacgtga cttgctt chr7:22912237-22912257 2 1.51e-05 A TCACGTGA GATGCCCATG chr17:26372517-26372537 3 1.51e-05 ta tcacgtga tTCGGGTCTT chr16:72643979-72643999 1 1.51e-05 . TCACGTGA TTTTTGCAAA chr14:105531208-10553122 1 1.51e-05 . TCACGTGA CTGGGCCAAC chr2:178077438-178077458 12 1.51e-05 GGAAAACGCG TCACGTGA C chr5:14174638-14174658 10 1.51e-05 TTCTGATGG TCACGTGA TGG chr15:70551488-70551508 9 1.51e-05 gagctcag tcacgtga cctc chrX:100872984-100873004 1 1.51e-05 . TCACGTGA CGGCCACGTC chr4:87935863-87935883 10 1.51e-05 CCAAGATTA TCACGTGA CTT chr7:5269745-5269765 11 1.51e-05 GACTCTGGGG TCACGTGA CT chr15:76050870-76050890 9 1.51e-05 TGTCCAAG TCACGTGA TCGT chr21:47564027-47564047 4 1.51e-05 gac tcacgtga ccttatcaa chr2:158220248-158220268 6 1.51e-05 AAGCA TCACGTGA CATATTA chr20:32179935-32179955 12 1.51e-05 ggtgggcgga tcacgtga t chr2:20386445-20386465 7 4.30e-05 CAGATA TCATGTGA TCGCTG chr17:72510754-72510774 4 4.30e-05 tga tcatgtga tgagtgatg chr4:159726847-159726867 1 4.30e-05 . TCACATGA GAGCCATTAA chr22:22523106-22523126 11 4.30e-05 GATATCAGGA TCACATGA CC chr2:86088439-86088459 10 4.30e-05 ATGATGTAG TCATGTGA GAA chr1:156265472-156265492 3 4.30e-05 GG TCACATGA CTCGCGTTCA chr2:160470704-160470724 6 4.30e-05 CTTGG TCATGTGA CCAAACC chr11:120197693-12019771 8 4.30e-05 CCATGTG TCATGTGA CCTCT chr11:120214330-12021435 8 4.30e-05 ATCACAG TCACATGA CAGGC chr19:11487991-11488011 12 4.30e-05 gtgactgggg tcatgtga c chrX:24497373-24497393 1 4.30e-05 . TCATGTGA TGTGCTCATG chr6:109780284-109780304 13 5.92e-05 caccaaggaa ccacgtga chr20:1103273-1103293 4 5.92e-05 AAA CCACGTGA CTGTGTACT chr3:16883532-16883552 5 5.92e-05 GGGG CCACGTGA CGCCTGTG chr19:54011581-54011601 10 5.92e-05 ccagccgca ccacgtga ccc chr14:64212951-64212971 9 5.92e-05 acctctgg ccacgtga ctcc chr14:31733855-31733875 5 5.92e-05 ATGA CCACGTGA TGAAAAAT chr17:46688395-46688415 7 5.92e-05 TCCGGA CCACGTGA CCCCGC chr1:44440567-44440587 7 7.60e-05 GTGGGG TCACGTGG TACCGG chr3:15387427-15387447 7 7.60e-05 ctgccg tcacgtgg aaggtt chr7:73707887-73707907 3 7.60e-05 GG TCACGTGG TCTCTGGGGC chr17:80455121-80455141 8 7.60e-05 CCGGCCG TCACGTGG GAGGT chr1:1440577-1440597 1 7.60e-05 . tcacgtgg gtcacgtgtc chr16:29832597-29832617 1 7.60e-05 . TCACGTGG GGTATCAGGT chr3:113473550-113473570 7 8.88e-05 ACTTAA TCATATGA CAGAAT chr1:2487190-2487210 12 1.19e-04 TCACGAGGTT CCATGTGA T chr2:43449186-43449206 12 1.19e-04 GCTACCGCAG CCACATGA T chr6:111720941-111720961 5 1.19e-04 gggg ccacatga cacccaca chr13:30969732-30969752 6 1.19e-04 GTGTG CCATGTGA CCTGGAC chr9:74825548-74825568 1 1.19e-04 . CCATGTGA CTTTTCTGAG chr19:49284176-49284196 12 1.19e-04 agtcacgtgt ccatgtga c chr1:90418770-90418790 12 1.49e-04 gtggtcagag tcatgtgg t chr15:57324066-57324086 1 1.49e-04 . tcacatgg taatgacatc chr2:178260517-178260537 10 1.49e-04 GTTGTTTTA TCACATGG TTG chr11:28127673-28127693 10 1.49e-04 TGTGATGCA TCAcatgg cat chr2:25496374-25496394 13 1.84e-04 GTGAAGTGCC CCACGTGG chr7:32930240-32930260 10 2.12e-04 GTATAAACA ACACGTGA CCA chr7:99942628-99942648 3 2.61e-04 ag tcacgtgt ccaccagaca chr20:4795810-4795830 2 2.61e-04 C TCCCGTGA CCCCTGAATA chr6:42204670-42204690 2 2.61e-04 A GCACGTGA CTCAAGGGGA chr9:126089143-126089163 3 2.75e-04 GG TCATATGG CAACATGAGG chr10:46222620-46222640 3 2.91e-04 GA TCACGTGC GGGTTCTGTC chr20:5037755-5037775 2 3.55e-04 c tcatggga gcactccccg chr3:156782360-156782380 9 3.55e-04 ATGACAAG TCACAGGA TCAG chr17:8762904-8762924 5 3.55e-04 tcag ccatgtgg gtgggcat chr7:156713328-156713348 1 3.55e-04 . tcatggga cagggagccc chr17:6950330-6950350 2 3.55e-04 a tcacagga cgggagggcc chr17:7236141-7236161 2 3.55e-04 a tcacagga cagggggccc chr22:42929505-42929525 12 3.82e-04 tgtctggtgg acacatga c chr12:46786680-46786700 7 3.82e-04 TGTAGT ACATGTGA TGTGGC chr2:178104801-178104821 4 4.71e-04 TGG GCACATGA TTTATTCCA chr8:37273983-37274003 8 4.71e-04 cccggca gcatgtga cagag chr15:45076632-45076652 1 4.71e-04 . tcatgtgt ccaccggaca chr7:158627925-158627945 13 4.71e-04 tggccccctg tcccatga chr22:50972978-50972998 12 4.71e-04 ggggcccctg tcctgtga t chr6:39576990-39577010 5 4.86e-04 GAAG TCACCTGA CCATTCAC chr1:153934666-153934686 6 5.68e-04 GCAAG TCACATGC CCAGGCC chr17:79997070-79997090 12 7.39e-04 gcgccccctg tcctatga t chr7:116443106-116443126 1 8.62e-04 . CCACATGT CTAAAGTCAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr9:138391741-138391761 1.5e-05 12_[+1] chr11:574360-574380 1.5e-05 5_[+1]_7 chr7:22912237-22912257 1.5e-05 1_[+1]_11 chr17:26372517-26372537 1.5e-05 2_[+1]_10 chr16:72643979-72643999 1.5e-05 [+1]_12 chr14:105531208-10553122 1.5e-05 [+1]_12 chr2:178077438-178077458 1.5e-05 11_[+1]_1 chr5:14174638-14174658 1.5e-05 9_[+1]_3 chr15:70551488-70551508 1.5e-05 8_[+1]_4 chrX:100872984-100873004 1.5e-05 [+1]_12 chr4:87935863-87935883 1.5e-05 9_[+1]_3 chr7:5269745-5269765 1.5e-05 10_[+1]_2 chr15:76050870-76050890 1.5e-05 8_[+1]_4 chr21:47564027-47564047 1.5e-05 3_[+1]_9 chr2:158220248-158220268 1.5e-05 5_[+1]_7 chr20:32179935-32179955 1.5e-05 11_[+1]_1 chr2:20386445-20386465 4.3e-05 6_[+1]_6 chr17:72510754-72510774 4.3e-05 3_[+1]_9 chr4:159726847-159726867 4.3e-05 [+1]_12 chr22:22523106-22523126 4.3e-05 10_[+1]_2 chr2:86088439-86088459 4.3e-05 9_[+1]_3 chr1:156265472-156265492 4.3e-05 2_[+1]_10 chr2:160470704-160470724 4.3e-05 5_[+1]_7 chr11:120197693-12019771 4.3e-05 7_[+1]_5 chr11:120214330-12021435 4.3e-05 7_[+1]_5 chr19:11487991-11488011 4.3e-05 11_[+1]_1 chrX:24497373-24497393 4.3e-05 [+1]_12 chr6:109780284-109780304 5.9e-05 12_[+1] chr20:1103273-1103293 5.9e-05 3_[+1]_9 chr3:16883532-16883552 5.9e-05 4_[+1]_8 chr19:54011581-54011601 5.9e-05 9_[+1]_3 chr14:64212951-64212971 5.9e-05 8_[+1]_4 chr14:31733855-31733875 5.9e-05 4_[+1]_8 chr17:46688395-46688415 5.9e-05 6_[+1]_6 chr1:44440567-44440587 7.6e-05 6_[+1]_6 chr3:15387427-15387447 7.6e-05 6_[+1]_6 chr7:73707887-73707907 7.6e-05 2_[+1]_10 chr17:80455121-80455141 7.6e-05 7_[+1]_5 chr1:1440577-1440597 7.6e-05 [+1]_12 chr16:29832597-29832617 7.6e-05 [+1]_12 chr3:113473550-113473570 8.9e-05 6_[+1]_6 chr1:2487190-2487210 0.00012 11_[+1]_1 chr2:43449186-43449206 0.00012 11_[+1]_1 chr6:111720941-111720961 0.00012 4_[+1]_8 chr13:30969732-30969752 0.00012 5_[+1]_7 chr9:74825548-74825568 0.00012 [+1]_12 chr19:49284176-49284196 0.00012 11_[+1]_1 chr1:90418770-90418790 0.00015 11_[+1]_1 chr15:57324066-57324086 0.00015 [+1]_12 chr2:178260517-178260537 0.00015 9_[+1]_3 chr11:28127673-28127693 0.00015 9_[+1]_3 chr2:25496374-25496394 0.00018 12_[+1] chr7:32930240-32930260 0.00021 9_[+1]_3 chr7:99942628-99942648 0.00026 2_[+1]_10 chr20:4795810-4795830 0.00026 1_[+1]_11 chr6:42204670-42204690 0.00026 1_[+1]_11 chr9:126089143-126089163 0.00027 2_[+1]_10 chr10:46222620-46222640 0.00029 2_[+1]_10 chr20:5037755-5037775 0.00035 1_[+1]_11 chr3:156782360-156782380 0.00035 8_[+1]_4 chr17:8762904-8762924 0.00035 4_[+1]_8 chr7:156713328-156713348 0.00035 [+1]_12 chr17:6950330-6950350 0.00035 1_[+1]_11 chr17:7236141-7236161 0.00035 1_[+1]_11 chr22:42929505-42929525 0.00038 11_[+1]_1 chr12:46786680-46786700 0.00038 6_[+1]_6 chr2:178104801-178104821 0.00047 3_[+1]_9 chr8:37273983-37274003 0.00047 7_[+1]_5 chr15:45076632-45076652 0.00047 [+1]_12 chr7:158627925-158627945 0.00047 12_[+1] chr22:50972978-50972998 0.00047 11_[+1]_1 chr6:39576990-39577010 0.00049 4_[+1]_8 chr1:153934666-153934686 0.00057 5_[+1]_7 chr17:79997070-79997090 0.00074 11_[+1]_1 chr7:116443106-116443126 0.00086 [+1]_12 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCACGTGA width=8 seqs=75 chr9:138391741-138391761 ( 13) TCACGTGA 1 chr11:574360-574380 ( 6) TCACGTGA 1 chr7:22912237-22912257 ( 2) TCACGTGA 1 chr17:26372517-26372537 ( 3) TCACGTGA 1 chr16:72643979-72643999 ( 1) TCACGTGA 1 chr14:105531208-10553122 ( 1) TCACGTGA 1 chr2:178077438-178077458 ( 12) TCACGTGA 1 chr5:14174638-14174658 ( 10) TCACGTGA 1 chr15:70551488-70551508 ( 9) TCACGTGA 1 chrX:100872984-100873004 ( 1) TCACGTGA 1 chr4:87935863-87935883 ( 10) TCACGTGA 1 chr7:5269745-5269765 ( 11) TCACGTGA 1 chr15:76050870-76050890 ( 9) TCACGTGA 1 chr21:47564027-47564047 ( 4) TCACGTGA 1 chr2:158220248-158220268 ( 6) TCACGTGA 1 chr20:32179935-32179955 ( 12) TCACGTGA 1 chr2:20386445-20386465 ( 7) TCATGTGA 1 chr17:72510754-72510774 ( 4) TCATGTGA 1 chr4:159726847-159726867 ( 1) TCACATGA 1 chr22:22523106-22523126 ( 11) TCACATGA 1 chr2:86088439-86088459 ( 10) TCATGTGA 1 chr1:156265472-156265492 ( 3) TCACATGA 1 chr2:160470704-160470724 ( 6) TCATGTGA 1 chr11:120197693-12019771 ( 8) TCATGTGA 1 chr11:120214330-12021435 ( 8) TCACATGA 1 chr19:11487991-11488011 ( 12) TCATGTGA 1 chrX:24497373-24497393 ( 1) TCATGTGA 1 chr6:109780284-109780304 ( 13) CCACGTGA 1 chr20:1103273-1103293 ( 4) CCACGTGA 1 chr3:16883532-16883552 ( 5) CCACGTGA 1 chr19:54011581-54011601 ( 10) CCACGTGA 1 chr14:64212951-64212971 ( 9) CCACGTGA 1 chr14:31733855-31733875 ( 5) CCACGTGA 1 chr17:46688395-46688415 ( 7) CCACGTGA 1 chr1:44440567-44440587 ( 7) TCACGTGG 1 chr3:15387427-15387447 ( 7) TCACGTGG 1 chr7:73707887-73707907 ( 3) TCACGTGG 1 chr17:80455121-80455141 ( 8) TCACGTGG 1 chr1:1440577-1440597 ( 1) TCACGTGG 1 chr16:29832597-29832617 ( 1) TCACGTGG 1 chr3:113473550-113473570 ( 7) TCATATGA 1 chr1:2487190-2487210 ( 12) CCATGTGA 1 chr2:43449186-43449206 ( 12) CCACATGA 1 chr6:111720941-111720961 ( 5) CCACATGA 1 chr13:30969732-30969752 ( 6) CCATGTGA 1 chr9:74825548-74825568 ( 1) CCATGTGA 1 chr19:49284176-49284196 ( 12) CCATGTGA 1 chr1:90418770-90418790 ( 12) TCATGTGG 1 chr15:57324066-57324086 ( 1) TCACATGG 1 chr2:178260517-178260537 ( 10) TCACATGG 1 chr11:28127673-28127693 ( 10) TCACATGG 1 chr2:25496374-25496394 ( 13) CCACGTGG 1 chr7:32930240-32930260 ( 10) ACACGTGA 1 chr7:99942628-99942648 ( 3) TCACGTGT 1 chr20:4795810-4795830 ( 2) TCCCGTGA 1 chr6:42204670-42204690 ( 2) GCACGTGA 1 chr9:126089143-126089163 ( 3) TCATATGG 1 chr10:46222620-46222640 ( 3) TCACGTGC 1 chr20:5037755-5037775 ( 2) TCATGGGA 1 chr3:156782360-156782380 ( 9) TCACAGGA 1 chr17:8762904-8762924 ( 5) CCATGTGG 1 chr7:156713328-156713348 ( 1) TCATGGGA 1 chr17:6950330-6950350 ( 2) TCACAGGA 1 chr17:7236141-7236161 ( 2) TCACAGGA 1 chr22:42929505-42929525 ( 12) ACACATGA 1 chr12:46786680-46786700 ( 7) ACATGTGA 1 chr2:178104801-178104821 ( 4) GCACATGA 1 chr8:37273983-37274003 ( 8) GCATGTGA 1 chr15:45076632-45076652 ( 1) TCATGTGT 1 chr7:158627925-158627945 ( 13) TCCCATGA 1 chr22:50972978-50972998 ( 12) TCCTGTGA 1 chr6:39576990-39577010 ( 5) TCACCTGA 1 chr1:153934666-153934686 ( 6) TCACATGC 1 chr17:79997070-79997090 ( 12) TCCTATGA 1 chr7:116443106-116443126 ( 1) CCACATGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 7.47226 E= 2.3e-086 -257 -27 -272 155 -1287 196 -1287 -1287 199 -227 -1287 -1287 -1287 146 -1287 28 16 -427 145 -1287 -1287 -1287 -198 195 -1287 -1287 192 -1287 167 -327 -60 -259 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 75 E= 2.3e-086 0.040000 0.213333 0.040000 0.706667 0.000000 1.000000 0.000000 0.000000 0.946667 0.053333 0.000000 0.000000 0.000000 0.706667 0.000000 0.293333 0.266667 0.013333 0.720000 0.000000 0.000000 0.000000 0.066667 0.933333 0.000000 0.000000 1.000000 0.000000 0.760000 0.026667 0.173333 0.040000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCACGTGA MEME-1 regular expression -------------------------------------------------------------------------------- [TC]CA[CT][GA]TGA -------------------------------------------------------------------------------- Time 1.95 secs. ******************************************************************************** ******************************************************************************** MOTIF GCCCCCTG MEME-2 width = 8 sites = 9 llr = 84 E-value = 1.8e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif GCCCCCTG MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C :8a99a:1 probability G a2:1:::9 matrix T ::::1:a: bits 2.1 * 1.9 * * ** 1.7 * * ** 1.4 * ****** Relative 1.2 ******** Entropy 1.0 ******** (13.4 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GCCCCCTG consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCCCCTG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:31004575-31004595 4 1.91e-05 aag gccccctg tccggtgga chr14:72663205-72663225 5 1.91e-05 ACAT GCCCCCTG TTCCTCCT chr7:158627925-158627945 5 1.91e-05 aatg gccccctg tcccatga chr17:79997070-79997090 4 1.91e-05 agc gccccctg tcctatgat chr15:76027654-76027674 4 1.91e-05 agg gccccctg ttctgtgat chr22:50972978-50972998 4 3.85e-05 agg ggcccctg tcctgtgat chr14:106996079-10699609 2 7.50e-05 t gccctctg tctggtggac chr2:241526077-241526097 13 9.44e-05 GTGCGATTGG GCCGCCTG chr11:95524241-95524261 13 1.13e-04 TGGGTTCAGC GGCCCCTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCCCCTG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:31004575-31004595 1.9e-05 3_[+2]_9 chr14:72663205-72663225 1.9e-05 4_[+2]_8 chr7:158627925-158627945 1.9e-05 4_[+2]_8 chr17:79997070-79997090 1.9e-05 3_[+2]_9 chr15:76027654-76027674 1.9e-05 3_[+2]_9 chr22:50972978-50972998 3.8e-05 3_[+2]_9 chr14:106996079-10699609 7.5e-05 1_[+2]_11 chr2:241526077-241526097 9.4e-05 12_[+2] chr11:95524241-95524261 0.00011 12_[+2] -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCCCCTG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GCCCCCTG width=8 seqs=9 chr12:31004575-31004595 ( 4) GCCCCCTG 1 chr14:72663205-72663225 ( 5) GCCCCCTG 1 chr7:158627925-158627945 ( 5) GCCCCCTG 1 chr17:79997070-79997090 ( 4) GCCCCCTG 1 chr15:76027654-76027674 ( 4) GCCCCCTG 1 chr22:50972978-50972998 ( 4) GGCCCCTG 1 chr14:106996079-10699609 ( 2) GCCCTCTG 1 chr2:241526077-241526097 ( 13) GCCGCCTG 1 chr11:95524241-95524261 ( 13) GGCCCCTC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCCCCTG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.62696 E= 1.8e+002 -982 -982 192 -982 -982 159 -24 -982 -982 196 -982 -982 -982 179 -124 -982 -982 179 -982 -111 -982 196 -982 -982 -982 -982 -982 205 -982 -121 175 -982 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCCCCTG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 9 E= 1.8e+002 0.000000 0.000000 1.000000 0.000000 0.000000 0.777778 0.222222 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.888889 0.111111 0.000000 0.000000 0.888889 0.000000 0.111111 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.111111 0.888889 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GCCCCCTG MEME-2 regular expression -------------------------------------------------------------------------------- G[CG]CCCCTG -------------------------------------------------------------------------------- Time 2.66 secs. ******************************************************************************** ******************************************************************************** MOTIF CTCTGGGG MEME-3 width = 8 sites = 8 llr = 74 E-value = 5.4e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTCTGGGG MEME-3 Description -------------------------------------------------------------------------------- Simplified A :1:::::1 pos.-specific C 9:a3:::: probability G 1:::aaa9 matrix T :9:8:::: bits 2.1 1.9 * *** 1.7 * *** 1.4 *** **** Relative 1.2 ******** Entropy 1.0 ******** (13.3 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTCTGGGG consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTGGGG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:73707887-73707907 12 1.85e-05 GTCACGTGGT CTCTGGGG C chr10:50396452-50396472 3 1.85e-05 GG CTCTGGGG ACAGGACAAG chr7:5269745-5269765 3 1.85e-05 GA CTCTGGGG TCACGTGACT chr6:150326481-150326501 8 3.83e-05 CGCCCTG CTCCGGGG CTCGT chr1:6661312-6661332 12 3.83e-05 TGTTTACAGG CTCCGGGG A chr11:63949175-63949195 5 5.50e-05 ATCA CTCTGGGA CGTCACGT chr3:9695471-9695491 11 9.22e-05 TAGTGTACAT GTCTGGGG AG chr4:48205573-48205593 8 9.22e-05 ACCCAGA CACTGGGG TCAGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTGGGG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:73707887-73707907 1.8e-05 11_[+3]_1 chr10:50396452-50396472 1.8e-05 2_[+3]_10 chr7:5269745-5269765 1.8e-05 2_[+3]_10 chr6:150326481-150326501 3.8e-05 7_[+3]_5 chr1:6661312-6661332 3.8e-05 11_[+3]_1 chr11:63949175-63949195 5.5e-05 4_[+3]_8 chr3:9695471-9695491 9.2e-05 10_[+3]_2 chr4:48205573-48205593 9.2e-05 7_[+3]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTGGGG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTCTGGGG width=8 seqs=8 chr7:73707887-73707907 ( 12) CTCTGGGG 1 chr10:50396452-50396472 ( 3) CTCTGGGG 1 chr7:5269745-5269765 ( 3) CTCTGGGG 1 chr6:150326481-150326501 ( 8) CTCCGGGG 1 chr1:6661312-6661332 ( 12) CTCCGGGG 1 chr11:63949175-63949195 ( 5) CTCTGGGA 1 chr3:9695471-9695491 ( 11) GTCTGGGG 1 chr4:48205573-48205593 ( 8) CACTGGGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTGGGG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.66267 E= 5.4e+003 -965 176 -107 -965 -93 -965 -965 186 -965 196 -965 -965 -965 -4 -965 164 -965 -965 192 -965 -965 -965 192 -965 -965 -965 192 -965 -93 -965 173 -965 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTGGGG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 8 E= 5.4e+003 0.000000 0.875000 0.125000 0.000000 0.125000 0.000000 0.000000 0.875000 0.000000 1.000000 0.000000 0.000000 0.000000 0.250000 0.000000 0.750000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.125000 0.000000 0.875000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCTGGGG MEME-3 regular expression -------------------------------------------------------------------------------- CTC[TC]GGGG -------------------------------------------------------------------------------- Time 3.36 secs. ******************************************************************************** ******************************************************************************** MOTIF BARAGTCA MEME-4 width = 8 sites = 12 llr = 99 E-value = 3.5e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif BARAGTCA MEME-4 Description -------------------------------------------------------------------------------- Simplified A 1a58:::a pos.-specific C 3:2:::a: probability G 3:32a::: matrix T 3:1::a:: bits 2.1 * * * 1.9 * **** 1.7 * **** 1.4 * ***** Relative 1.2 * ***** Entropy 1.0 * ***** (11.9 bits) 0.8 * ***** 0.6 * ***** 0.4 * ***** 0.2 ******** 0.0 -------- Multilevel CAAAGTCA consensus T G sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BARAGTCA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:116443106-116443126 10 1.26e-05 CCACATGTC TAAAGTCA GTC chr1:221913149-221913169 12 1.26e-05 AAAGAAAGAA TAAAGTCA C chr9:76788350-76788370 12 2.62e-05 ACCTAGTACT CAAAGTCA T chr16:27760339-27760359 13 5.40e-05 AAAACACCGT TAGAGTCA chr1:169281594-169281614 8 6.89e-05 tcaagct cagagtca ctgtg chr1:155188825-155188845 13 8.42e-05 TGATGACTAG GAGAGTCA chr14:51886591-51886611 10 9.79e-05 CTTGCTAGG TACAGTCA TGT chr13:113695818-11369583 9 1.13e-04 CCCATGAC CACAGTCA GTAT chr12:92879374-92879394 6 1.25e-04 GACAG AAAAGTCA AGATAAA chr10:103618692-10361871 12 1.82e-04 AATCTCTCAT CAAGGTCA C chr11:44578572-44578592 12 2.11e-04 ccagagaggt gaaggtca c chr4:143488105-143488125 13 2.38e-04 TAAGGTTTTT GATAGTCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BARAGTCA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:116443106-116443126 1.3e-05 9_[+4]_3 chr1:221913149-221913169 1.3e-05 11_[+4]_1 chr9:76788350-76788370 2.6e-05 11_[+4]_1 chr16:27760339-27760359 5.4e-05 12_[+4] chr1:169281594-169281614 6.9e-05 7_[+4]_5 chr1:155188825-155188845 8.4e-05 12_[+4] chr14:51886591-51886611 9.8e-05 9_[+4]_3 chr13:113695818-11369583 0.00011 8_[+4]_4 chr12:92879374-92879394 0.00013 5_[+4]_7 chr10:103618692-10361871 0.00018 11_[+4]_1 chr11:44578572-44578592 0.00021 11_[+4]_1 chr4:143488105-143488125 0.00024 12_[+4] -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BARAGTCA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF BARAGTCA width=8 seqs=12 chr7:116443106-116443126 ( 10) TAAAGTCA 1 chr1:221913149-221913169 ( 12) TAAAGTCA 1 chr9:76788350-76788370 ( 12) CAAAGTCA 1 chr16:27760339-27760359 ( 13) TAGAGTCA 1 chr1:169281594-169281614 ( 8) CAGAGTCA 1 chr1:155188825-155188845 ( 13) GAGAGTCA 1 chr14:51886591-51886611 ( 10) TACAGTCA 1 chr13:113695818-11369583 ( 9) CACAGTCA 1 chr12:92879374-92879394 ( 6) AAAAGTCA 1 chr10:103618692-10361871 ( 12) CAAGGTCA 1 chr11:44578572-44578592 ( 12) GAAGGTCA 1 chr4:143488105-143488125 ( 13) GATAGTCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BARAGTCA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 6.84639 E= 3.5e+002 -151 37 -8 47 207 -1023 -1023 -1023 107 -63 -8 -153 181 -1023 -66 -1023 -1023 -1023 192 -1023 -1023 -1023 -1023 205 -1023 196 -1023 -1023 207 -1023 -1023 -1023 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BARAGTCA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 12 E= 3.5e+002 0.083333 0.333333 0.250000 0.333333 1.000000 0.000000 0.000000 0.000000 0.500000 0.166667 0.250000 0.083333 0.833333 0.000000 0.166667 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BARAGTCA MEME-4 regular expression -------------------------------------------------------------------------------- [CTG]A[AG]AGTCA -------------------------------------------------------------------------------- Time 5.23 secs. ******************************************************************************** ******************************************************************************** MOTIF AAAGAAAG MEME-5 width = 8 sites = 2 llr = 23 E-value = 4.1e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAAGAAAG MEME-5 Description -------------------------------------------------------------------------------- Simplified A aaa:aaa: pos.-specific C :::::::: probability G :::a:::a matrix T :::::::: bits 2.1 *** *** 1.9 ******** 1.7 ******** 1.4 ******** Relative 1.2 ******** Entropy 1.0 ******** (16.3 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AAAGAAAG consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:12074117-12074137 4 1.26e-05 CTC AAAGAAAG CTGTGTCTT chr1:221913149-221913169 2 1.26e-05 G AAAGAAAG AATAAAGTCA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:12074117-12074137 1.3e-05 3_[+5]_9 chr1:221913149-221913169 1.3e-05 1_[+5]_11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAAGAAAG width=8 seqs=2 chr2:12074117-12074137 ( 4) AAAGAAAG 1 chr1:221913149-221913169 ( 2) AAAGAAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 10.6653 E= 4.1e+003 206 -765 -765 -765 206 -765 -765 -765 206 -765 -765 -765 -765 -765 192 -765 206 -765 -765 -765 206 -765 -765 -765 206 -765 -765 -765 -765 -765 192 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 4.1e+003 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAAGAAAG MEME-5 regular expression -------------------------------------------------------------------------------- AAAGAAAG -------------------------------------------------------------------------------- Time 8.04 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr20:32179935-32179955 1.53e-02 11_[+1(1.51e-05)]_1 chr4:143488105-143488125 2.08e-01 20 chr2:158220248-158220268 2.93e-02 5_[+1(1.51e-05)]_7 chr4:89978360-89978380 2.65e-01 20 chr17:7236141-7236161 1.54e-02 20 chr17:6950330-6950350 6.22e-02 20 chr6:15951401-15951421 6.04e-02 20 chr15:76027654-76027674 3.32e-03 3_[+2(1.91e-05)]_9 chr15:78645614-78645634 8.15e-01 20 chr21:47564027-47564047 2.51e-02 3_[+1(1.51e-05)]_9 chr2:8820600-8820620 3.82e-01 20 chr17:79997070-79997090 2.66e-03 3_[+2(1.91e-05)]_9 chr1:178387898-178387918 4.98e-01 20 chr22:50972978-50972998 1.38e-03 3_[+2(3.85e-05)]_9 chr6:14373152-14373172 6.77e-01 20 chr12:4246387-4246407 6.92e-01 20 chr19:49284176-49284196 6.15e-02 20 chr9:74825548-74825568 8.67e-02 20 chr15:76050870-76050890 1.03e-03 8_[+1(1.51e-05)]_4 chrX:57259629-57259649 7.71e-02 20 chr5:72792885-72792905 1.46e-01 20 chr13:111024687-11102470 9.08e-01 20 chr13:113695818-11369583 3.09e-02 20 chr10:14050596-14050616 2.14e-01 20 chr10:79532829-79532849 4.66e-01 20 chr12:92879374-92879394 2.24e-02 20 chr8:102216176-102216196 9.97e-01 20 chr1:221913149-221913169 1.27e-04 1_[+5(1.26e-05)]_2_[+4(1.26e-05)]_1 chr8:64082665-64082685 6.82e-01 20 chr7:158627925-158627945 1.44e-03 4_[+2(1.91e-05)]_8 chr11:28127673-28127693 1.38e-01 20 chr3:113473550-113473570 4.87e-02 6_[+1(8.88e-05)]_6 chr4:176974117-176974137 6.51e-01 20 chr2:178260517-178260537 1.17e-01 20 chr2:152683425-152683445 6.64e-01 20 chr16:10187614-10187634 9.13e-01 20 chr11:44578572-44578592 8.56e-02 20 chr20:37971267-37971287 9.04e-01 20 chr7:5269745-5269765 9.98e-06 2_[+3(1.85e-05)]_[+1(1.51e-05)]_2 chr5:180233740-180233760 2.61e-01 20 chr15:38546918-38546938 4.40e-01 20 chr12:46786680-46786700 3.13e-01 20 chr6:126407899-126407919 9.64e-01 20 chr3:196647795-196647815 3.37e-01 20 chr11:17230036-17230056 9.32e-01 20 chr20:1878351-1878371 3.28e-01 20 chrX:55744141-55744161 4.77e-01 20 chr9:76788350-76788370 2.02e-02 11_[+4(2.62e-05)]_1 chr6:29898002-29898022 4.12e-01 20 chr9:114987437-114987457 7.86e-01 20 chr10:103618692-10361871 1.27e-01 20 chr17:46688395-46688415 2.92e-02 6_[+1(5.92e-05)]_6 chr14:31733855-31733875 2.16e-02 4_[+1(5.92e-05)]_8 chr1:180182713-180182733 7.13e-01 20 chr1:64485693-64485713 5.84e-01 20 chr16:29832597-29832617 2.64e-02 [+1(7.60e-05)]_12 chrX:24497373-24497393 3.49e-02 [+1(4.30e-05)]_12 chr19:8305390-8305410 5.37e-02 20 chr4:164471570-164471590 6.75e-01 20 chr7:1462655-1462675 4.80e-01 20 chr17:32001881-32001901 4.58e-01 20 chr3:49028425-49028445 9.87e-01 20 chrX:101914842-101914862 8.46e-01 20 chr5:139782383-139782403 7.78e-01 20 chr16:27760339-27760359 1.81e-02 12_[+4(5.40e-05)] chr22:42929505-42929525 1.86e-02 20 chr9:131084491-131084511 6.04e-01 20 chr19:11487991-11488011 2.05e-04 11_[+1(4.30e-05)]_1 chr5:142962687-142962707 9.42e-01 20 chr13:40644655-40644675 7.97e-01 20 chr1:28195747-28195767 5.97e-01 20 chr15:34610996-34611016 4.60e-01 20 chr15:74392578-74392598 7.13e-01 20 chr4:87935863-87935883 2.32e-02 9_[+1(1.51e-05)]_3 chr1:1440577-1440597 5.66e-03 [+1(7.60e-05)]_12 chr7:156713328-156713348 8.72e-03 20 chr11:95524241-95524261 4.82e-02 20 chr11:64836950-64836970 5.38e-01 20 chrX:100872984-100873004 3.59e-03 [+1(1.51e-05)]_12 chr10:77162196-77162216 4.44e-01 20 chr1:111759997-111760017 9.80e-01 20 chr1:155188825-155188845 8.48e-03 12_[+4(8.42e-05)] chr2:128588580-128588600 5.76e-01 20 chr10:69932349-69932369 4.17e-01 20 chr16:21963936-21963956 9.37e-01 20 chr14:64212951-64212971 4.11e-03 8_[+1(5.92e-05)]_4 chr1:226271209-226271229 5.53e-01 20 chr16:89428877-89428897 5.00e-01 20 chr1:8229969-8229989 5.67e-01 20 chr1:220445896-220445916 5.48e-01 20 chr19:54011581-54011601 4.80e-02 9_[+1(5.92e-05)]_3 chrX:114797065-114797085 2.21e-01 20 chr7:116443106-116443126 2.43e-04 9_[+4(1.26e-05)]_3 chr11:120214330-12021435 2.75e-04 7_[+1(4.30e-05)]_5 chr12:108662386-10866240 1.21e-01 20 chr11:63949175-63949195 8.12e-03 4_[+3(5.50e-05)]_8 chr1:236768123-236768143 5.59e-01 20 chr10:50396452-50396472 1.08e-02 2_[+3(1.85e-05)]_10 chr13:30969732-30969752 9.95e-03 20 chr17:80455121-80455141 3.89e-03 7_[+1(7.60e-05)]_5 chr6:26196337-26196357 6.30e-01 20 chr14:72663205-72663225 1.41e-02 4_[+2(1.91e-05)]_8 chr20:62066327-62066347 7.17e-01 20 chr19:19600226-19600246 5.24e-01 20 chr10:70480728-70480748 9.76e-01 20 chr5:119793710-119793730 7.57e-02 20 chr2:241526077-241526097 7.44e-02 12_[+2(9.44e-05)] chr2:130635089-130635109 8.46e-01 20 chr7:44656975-44656995 1.86e-01 20 chr11:120197693-12019771 3.83e-02 7_[+1(4.30e-05)]_5 chr20:570176-570196 7.17e-01 20 chr20:40321481-40321501 4.22e-01 20 chr20:32925970-32925990 6.75e-01 20 chr22:25481954-25481974 5.88e-01 20 chr2:160470704-160470724 8.58e-03 5_[+1(4.30e-05)]_7 chr6:42204670-42204690 8.82e-03 20 chr16:17458433-17458453 2.13e-01 20 chr4:22741787-22741807 4.21e-01 20 chr16:11666305-11666325 8.15e-01 20 chr22:46957591-46957611 6.13e-02 20 chr16:11457410-11457430 2.99e-01 20 chr13:98639284-98639304 8.82e-01 20 chr6:111720941-111720961 1.76e-02 20 chr19:12099487-12099507 7.03e-02 20 chr19:49005103-49005123 1.99e-01 20 chr1:156265472-156265492 2.11e-02 2_[+1(4.30e-05)]_10 chr10:70883916-70883936 4.43e-01 20 chr8:126591863-126591883 4.25e-01 20 chr2:86079367-86079387 9.69e-01 20 chr15:45076632-45076652 7.99e-02 20 chr12:31004575-31004595 1.19e-03 3_[+2(1.91e-05)]_9 chr10:89688893-89688913 6.06e-01 20 chr2:86088439-86088459 8.48e-03 9_[+1(4.30e-05)]_3 chr17:46534088-46534108 2.87e-01 20 chr15:96472646-96472666 8.66e-01 20 chr22:22523106-22523126 1.56e-02 10_[+1(4.30e-05)]_2 chr12:112451180-11245120 2.57e-01 20 chr3:16883532-16883552 5.20e-03 4_[+1(5.92e-05)]_8 chr15:57324066-57324086 1.14e-02 20 chr1:169281594-169281614 4.40e-02 7_[+4(6.89e-05)]_5 chr6:21847113-21847133 8.74e-01 20 chr15:70551488-70551508 2.70e-03 8_[+1(1.51e-05)]_4 chr6:39576990-39577010 4.36e-02 20 chr9:126089143-126089163 1.01e-01 20 chr12:111028785-11102880 6.47e-01 20 chr17:38753027-38753047 8.13e-01 20 chr9:1930555-1930575 1.33e-01 20 chr1:153934666-153934686 1.76e-02 20 chr1:6661312-6661332 4.69e-03 11_[+3(3.83e-05)]_1 chr8:37273983-37274003 1.13e-01 20 chr14:21148296-21148316 2.02e-01 20 chr1:1001152-1001172 1.62e-01 20 chr2:208576122-208576142 7.64e-01 20 chr4:159726847-159726867 3.72e-03 [+1(4.30e-05)]_12 chr9:5628621-5628641 7.78e-01 20 chr1:26860626-26860646 8.42e-02 20 chr20:1103273-1103293 1.13e-02 3_[+1(5.92e-05)]_9 chr16:68878232-68878252 1.94e-01 20 chr9:140016536-140016556 9.98e-01 20 chr7:73707887-73707907 2.85e-05 2_[+1(7.60e-05)]_1_[+3(1.85e-05)]_1 chr2:37753655-37753675 3.97e-01 20 chr19:17518319-17518339 6.50e-01 20 chr17:8762904-8762924 6.46e-02 20 chr6:47408602-47408622 7.63e-01 20 chr11:19333457-19333477 1.37e-01 20 chr8:56832514-56832534 9.90e-01 20 chr1:90418770-90418790 1.03e-03 6_[+4(6.89e-05)]_6 chr13:25268462-25268482 4.90e-01 20 chr6:167364616-167364636 7.51e-02 20 chr17:72510754-72510774 5.51e-02 3_[+1(4.30e-05)]_9 chr20:47377024-47377044 1.90e-01 20 chr4:114001455-114001475 9.15e-02 20 chr1:173446174-173446194 1.15e-01 20 chr1:44058791-44058811 8.37e-01 20 chr9:37719709-37719729 7.24e-01 20 chr4:36243625-36243645 9.90e-01 20 chr5:14174638-14174658 5.99e-04 9_[+1(1.51e-05)]_3 chr14:59743130-59743150 3.34e-01 20 chr7:116611460-116611480 3.65e-02 20 chr2:25496374-25496394 3.16e-02 20 chr16:22229468-22229488 7.07e-01 20 chr3:15387427-15387447 4.16e-03 6_[+1(7.60e-05)]_6 chr2:178077438-178077458 1.15e-02 11_[+1(1.51e-05)]_1 chr11:71814518-71814538 7.07e-01 20 chr17:63035959-63035979 9.07e-01 20 chr14:68940729-68940749 2.20e-01 20 chr6:159495536-159495556 3.50e-01 20 chr15:44084254-44084274 7.61e-01 20 chr3:132136288-132136308 2.80e-02 20 chr2:43449186-43449206 1.88e-02 20 chr14:105531208-10553122 7.05e-04 [+1(1.51e-05)]_12 chrX:37646099-37646119 7.88e-01 20 chr2:12074117-12074137 3.51e-03 3_[+5(1.26e-05)]_9 chr2:178104801-178104821 1.28e-01 20 chr20:4795810-4795830 2.55e-03 20 chr21:43953055-43953075 4.26e-01 20 chr18:21699183-21699203 9.07e-01 20 chr4:48205573-48205593 6.86e-03 7_[+3(9.22e-05)]_5 chrX:146993365-146993385 9.93e-01 20 chr1:2487190-2487210 6.23e-02 20 chr17:46655745-46655765 3.88e-01 20 chr11:62538740-62538760 6.18e-01 20 chr19:50872610-50872630 5.39e-01 20 chr2:20386445-20386465 3.86e-02 6_[+1(4.30e-05)]_6 chr17:8095630-8095650 6.84e-01 20 chr1:11796105-11796125 8.38e-01 20 chr3:112495127-112495147 5.14e-01 20 chr7:99942628-99942648 9.62e-02 20 chr12:92756765-92756785 7.16e-01 20 chr16:72643979-72643999 3.85e-02 [+1(1.51e-05)]_12 chr10:11916892-11916912 3.72e-01 20 chr12:96336834-96336854 8.33e-01 20 chr14:51886591-51886611 1.04e-01 9_[+4(9.79e-05)]_3 chr7:32930240-32930260 3.25e-02 20 chr10:134373815-13437383 1.00e+00 20 chr6:106440463-106440483 2.23e-01 20 chr3:9695471-9695491 6.79e-02 10_[+3(9.22e-05)]_2 chr8:42623071-42623091 2.53e-01 20 chr18:3013566-3013586 1.89e-01 20 chr10:102756609-10275662 9.02e-01 20 chr2:231281274-231281294 9.55e-01 20 chr14:92573098-92573118 6.98e-01 20 chr1:44440567-44440587 1.27e-02 6_[+1(7.60e-05)]_6 chr16:15737462-15737482 1.00e+00 20 chr21:15899686-15899706 6.72e-01 20 chr3:57678886-57678906 6.98e-01 20 chr2:118955067-118955087 5.23e-03 20 chr2:36757618-36757638 2.87e-01 20 chr8:136537540-136537560 6.36e-01 20 chr19:47633955-47633975 5.97e-01 20 chr7:20327026-20327046 8.09e-01 20 chr14:61905428-61905448 9.94e-01 20 chr6:41256340-41256360 6.12e-01 20 chr6:150326481-150326501 4.42e-02 7_[+3(3.83e-05)]_5 chr17:26372517-26372537 1.73e-02 2_[+1(1.51e-05)]_10 chr7:22912237-22912257 7.41e-03 1_[+1(1.51e-05)]_11 chr18:43542624-43542644 5.58e-01 20 chr1:28559536-28559556 4.06e-01 20 chr3:156782360-156782380 3.32e-02 20 chr6:109780284-109780304 1.06e-02 12_[+1(5.92e-05)] chr22:32072782-32072802 7.73e-01 20 chr10:46222620-46222640 6.91e-02 20 chr11:574360-574380 1.18e-02 5_[+1(1.51e-05)]_7 chr20:5037755-5037775 3.82e-02 20 chr19:36545323-36545343 3.63e-01 20 chr2:118761020-118761040 7.52e-01 20 chr13:80096946-80096966 3.95e-01 20 chr9:138391741-138391761 3.06e-03 12_[+1(1.51e-05)] chr1:220621788-220621808 1.99e-01 20 chr14:106996079-10699609 2.08e-03 1_[+2(7.50e-05)]_11 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n10.farnam.hpc.yale.internal ********************************************************************************