******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/NR2C1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr16:22019369-22019389 1.0000 20 chr11:118868850-11886887 1.0000 20 chr8:182427-182447 1.0000 20 chr13:113344151-11334417 1.0000 20 chr8:144816257-144816277 1.0000 20 chr17:80009766-80009786 1.0000 20 chr19:1068299-1068319 1.0000 20 chr18:54318861-54318881 1.0000 20 chr16:30392838-30392858 1.0000 20 chr5:176981616-176981636 1.0000 20 chr16:30710525-30710545 1.0000 20 chr8:57906373-57906393 1.0000 20 chr1:27934043-27934063 1.0000 20 chr6:372801-372821 1.0000 20 chr17:80489049-80489069 1.0000 20 chr10:35625446-35625466 1.0000 20 chr9:72374983-72375003 1.0000 20 chr19:38806389-38806409 1.0000 20 chr16:12070495-12070515 1.0000 20 chr9:134406648-134406668 1.0000 20 chr10:103815532-10381555 1.0000 20 chr12:498815-498835 1.0000 20 chr1:19811967-19811987 1.0000 20 chr3:14989125-14989145 1.0000 20 chr3:37217886-37217906 1.0000 20 chr9:136223359-136223379 1.0000 20 chr8:124286555-124286575 1.0000 20 chr16:30569731-30569751 1.0000 20 chrX:103401975-103401995 1.0000 20 chr4:108641512-108641532 1.0000 20 chr11:64073603-64073623 1.0000 20 chr12:48551272-48551292 1.0000 20 chr3:119395992-119396012 1.0000 20 chr7:151038862-151038882 1.0000 20 chr19:50919390-50919410 1.0000 20 chr7:6865950-6865970 1.0000 20 chr4:658000-658020 1.0000 20 chr1:11862840-11862860 1.0000 20 chr6:169852619-169852639 1.0000 20 chr9:37568705-37568725 1.0000 20 chr1:3663922-3663942 1.0000 20 chr16:67700681-67700701 1.0000 20 chr22:47158758-47158778 1.0000 20 chr19:10197316-10197336 1.0000 20 chr1:762830-762850 1.0000 20 chr12:70637175-70637195 1.0000 20 chr7:5270597-5270617 1.0000 20 chr19:51963883-51963903 1.0000 20 chr22:51020959-51020979 1.0000 20 chr2:175901468-175901488 1.0000 20 chr1:78245298-78245318 1.0000 20 chr1:110752561-110752581 1.0000 20 chr11:64027205-64027225 1.0000 20 chr22:43659373-43659393 1.0000 20 chr3:33138080-33138100 1.0000 20 chr1:233085998-233086018 1.0000 20 chr22:51066510-51066530 1.0000 20 chrX:153775790-153775810 1.0000 20 chr16:47007608-47007628 1.0000 20 chr19:17420673-17420693 1.0000 20 chr14:95623969-95623989 1.0000 20 chr7:76751706-76751726 1.0000 20 chr21:45432649-45432669 1.0000 20 chr16:4850545-4850565 1.0000 20 chr9:35834849-35834869 1.0000 20 chr3:125153752-125153772 1.0000 20 chr14:70883804-70883824 1.0000 20 chr10:21814827-21814847 1.0000 20 chr19:2236828-2236848 1.0000 20 chr15:59981494-59981514 1.0000 20 chr4:57333738-57333758 1.0000 20 chr11:134123361-13412338 1.0000 20 chr20:42087859-42087879 1.0000 20 chr20:34287274-34287294 1.0000 20 chr12:95467329-95467349 1.0000 20 chr4:144106103-144106123 1.0000 20 chr10:89264610-89264630 1.0000 20 chr6:108616625-108616645 1.0000 20 chr5:114598573-114598593 1.0000 20 chr12:6665292-6665312 1.0000 20 chr6:146136037-146136057 1.0000 20 chr19:1173746-1173766 1.0000 20 chr12:133532917-13353293 1.0000 20 chr19:14229141-14229161 1.0000 20 chr1:151138036-151138056 1.0000 20 chr15:102521016-10252103 1.0000 20 chr6:43655528-43655548 1.0000 20 chr17:48799039-48799059 1.0000 20 chr1:155179064-155179084 1.0000 20 chr7:72971632-72971652 1.0000 20 chr6:96025652-96025672 1.0000 20 chr17:38083183-38083203 1.0000 20 chr10:99185823-99185843 1.0000 20 chr4:47013137-47013157 1.0000 20 chr12:96252682-96252702 1.0000 20 chr17:37027876-37027896 1.0000 20 chr2:207139617-207139637 1.0000 20 chr15:67835000-67835020 1.0000 20 chr19:18335077-18335097 1.0000 20 chr9:125675619-125675639 1.0000 20 chr5:79287071-79287091 1.0000 20 chr19:14528833-14528853 1.0000 20 chr13:50018495-50018515 1.0000 20 chr19:51403046-51403066 1.0000 20 chr16:31128975-31128995 1.0000 20 chr1:230202773-230202793 1.0000 20 chr11:62495902-62495922 1.0000 20 chr19:10363175-10363195 1.0000 20 chr19:35168203-35168223 1.0000 20 chr22:38349675-38349695 1.0000 20 chr15:55790615-55790635 1.0000 20 chr19:37178390-37178410 1.0000 20 chr10:103348011-10334803 1.0000 20 chr15:82555082-82555102 1.0000 20 chr5:67721061-67721081 1.0000 20 chrX:122866912-122866932 1.0000 20 chr7:97601679-97601699 1.0000 20 chr14:75593766-75593786 1.0000 20 chr7:39663161-39663181 1.0000 20 chr5:143550214-143550234 1.0000 20 chr2:232826402-232826422 1.0000 20 chr9:129567270-129567290 1.0000 20 chrX:48595713-48595733 1.0000 20 chr1:213224564-213224584 1.0000 20 chr2:3381145-3381165 1.0000 20 chr2:73441394-73441414 1.0000 20 chrX:54208933-54208953 1.0000 20 chr18:22006583-22006603 1.0000 20 chr7:135662078-135662098 1.0000 20 chr12:50794585-50794605 1.0000 20 chr19:44405979-44405999 1.0000 20 chr9:116036917-116036937 1.0000 20 chrX:69353756-69353776 1.0000 20 chr16:4401265-4401285 1.0000 20 chr7:127032756-127032776 1.0000 20 chr17:61920560-61920580 1.0000 20 chr16:30640198-30640218 1.0000 20 chr10:22994091-22994111 1.0000 20 chr15:60878098-60878118 1.0000 20 chr19:40315364-40315384 1.0000 20 chr19:633210-633230 1.0000 20 chr12:69864155-69864175 1.0000 20 chr19:6393224-6393244 1.0000 20 chr2:175260439-175260459 1.0000 20 chr7:39605977-39605997 1.0000 20 chr4:41937143-41937163 1.0000 20 chr2:27994602-27994622 1.0000 20 chr2:207024484-207024504 1.0000 20 chr16:30546289-30546309 1.0000 20 chr17:46185095-46185115 1.0000 20 chrX:1571460-1571480 1.0000 20 chr11:59382764-59382784 1.0000 20 chr6:31633708-31633728 1.0000 20 chr6:157253383-157253403 1.0000 20 chr1:1209226-1209246 1.0000 20 chr12:14538485-14538505 1.0000 20 chr5:1801520-1801540 1.0000 20 chr8:144635826-144635846 1.0000 20 chr1:168148108-168148128 1.0000 20 chr12:123868250-12386827 1.0000 20 chr17:37844290-37844310 1.0000 20 chr1:28415125-28415145 1.0000 20 chr2:39103089-39103109 1.0000 20 chr17:38975431-38975451 1.0000 20 chr17:31208259-31208279 1.0000 20 chr20:62339270-62339290 1.0000 20 chr12:107168294-10716831 1.0000 20 chr19:2328610-2328630 1.0000 20 chr2:190648258-190648278 1.0000 20 chr19:39616626-39616646 1.0000 20 chr20:19997955-19997975 1.0000 20 chr2:65648077-65648097 1.0000 20 chr14:35761584-35761604 1.0000 20 chr3:178865867-178865887 1.0000 20 chr9:140513122-140513142 1.0000 20 chr17:80709876-80709896 1.0000 20 chr9:95640392-95640412 1.0000 20 chr18:55719151-55719171 1.0000 20 chr17:35716182-35716202 1.0000 20 chr6:99873229-99873249 1.0000 20 chr17:79884596-79884616 1.0000 20 chr17:75446610-75446630 1.0000 20 chrX:2548754-2548774 1.0000 20 chr3:37285188-37285208 1.0000 20 chr2:152144858-152144878 1.0000 20 chr9:138986194-138986214 1.0000 20 chr22:31742349-31742369 1.0000 20 chr19:53400907-53400927 1.0000 20 chr17:1755830-1755850 1.0000 20 chr10:75541796-75541816 1.0000 20 chr5:154238183-154238203 1.0000 20 chr22:37260218-37260238 1.0000 20 chr3:14165931-14165951 1.0000 20 chr7:44240514-44240534 1.0000 20 chr3:119012164-119012184 1.0000 20 chr10:89577973-89577993 1.0000 20 chr6:24774998-24775018 1.0000 20 chr7:95401709-95401729 1.0000 20 chr16:85045147-85045167 1.0000 20 chr5:64920815-64920835 1.0000 20 chr16:89572037-89572057 1.0000 20 chr22:43485442-43485462 1.0000 20 chr5:78908302-78908322 1.0000 20 chr4:47916817-47916837 1.0000 20 chr20:34129923-34129943 1.0000 20 chr15:48623616-48623636 1.0000 20 chr4:1722992-1723012 1.0000 20 chr2:159312973-159312993 1.0000 20 chr19:41257718-41257738 1.0000 20 chrX:153251167-153251187 1.0000 20 chr19:51294442-51294462 1.0000 20 chr7:102389382-102389402 1.0000 20 chr5:14664781-14664801 1.0000 20 chr19:11513064-11513084 1.0000 20 chr3:49203798-49203818 1.0000 20 chr16:74330394-74330414 1.0000 20 chr2:231191871-231191891 1.0000 20 chr13:41837692-41837712 1.0000 20 chr2:44394946-44394966 1.0000 20 chr1:101360750-101360770 1.0000 20 chr3:141110365-141110385 1.0000 20 chr13:107019882-10701990 1.0000 20 chrX:46306674-46306694 1.0000 20 chr4:699175-699195 1.0000 20 chr7:74489602-74489622 1.0000 20 chr16:74402129-74402149 1.0000 20 chr6:10404882-10404902 1.0000 20 chr10:107567851-10756787 1.0000 20 chr5:149104183-149104203 1.0000 20 chr12:57146197-57146217 1.0000 20 chr7:5938271-5938291 1.0000 20 chr8:92082550-92082570 1.0000 20 chr1:95538469-95538489 1.0000 20 chr8:21897310-21897330 1.0000 20 chr5:125936615-125936635 1.0000 20 chr12:92899872-92899892 1.0000 20 chr3:52740091-52740111 1.0000 20 chr10:26986522-26986542 1.0000 20 chr10:43951143-43951163 1.0000 20 chr4:123844225-123844245 1.0000 20 chr19:49136822-49136842 1.0000 20 chr2:153573983-153574003 1.0000 20 chr8:130952054-130952074 1.0000 20 chr16:4784282-4784302 1.0000 20 chr11:191813-191833 1.0000 20 chr1:211849267-211849287 1.0000 20 chr8:28747327-28747347 1.0000 20 chr19:35865970-35865990 1.0000 20 chr13:98854541-98854561 1.0000 20 chr11:32605346-32605366 1.0000 20 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/GM12878/inference_raw/MEME/RankLinear0.6_10_NR2C1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/NR2C1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 5000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 5000 norand= no csites= 1000 Letter frequencies in dataset: A 0.183 C 0.309 G 0.311 T 0.197 Background letter frequencies (from file dataset with add-one prior applied): A 0.183 C 0.309 G 0.311 T 0.197 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CTGACCYY MEME-1 width = 8 sites = 39 llr = 297 E-value = 1.2e-022 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTGACCYY MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::1a:::: pos.-specific C 61::aa65 probability G 2:9::::1 matrix T 39::::44 bits 2.4 * 2.2 * 2.0 * * 1.7 * *** Relative 1.5 ***** Entropy 1.2 ***** (11.0 bits) 1.0 ****** 0.7 ****** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CTGACCCC consensus T TT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGACCYY MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:211849267-211849287 4 1.28e-05 CTT CTGACCTT TGCACTCTG chr2:65648077-65648097 9 1.28e-05 CTCTTTCT CTGACCTT CTCT chr22:37260218-37260238 5 3.30e-05 CCAG CTGACCTC TGAACCTT chr8:144635826-144635846 2 3.30e-05 G CTGACCTC TGCCCTCCTT chr6:43655528-43655548 4 3.30e-05 ACC CTGACCTC TCGTCCATT chr3:125153752-125153772 12 3.30e-05 TGTCTGACCC CTGACCTC T chr19:50919390-50919410 12 3.30e-05 CCCATGACCT CTGACCTC C chr13:113344151-11334417 2 3.30e-05 t ctgacctc tgccctctgc chr4:699175-699195 12 5.31e-05 aacccgaccc ctgaccct a chr19:10363175-10363195 10 5.31e-05 CAGAGAGGT CTGACCCT TGA chr8:144816257-144816277 7 5.31e-05 TGACCC CTGACCCT CGCCCC chr7:95401709-95401729 5 9.29e-05 CGAA TTGACCTT TCCAGGTC chr20:62339270-62339290 1 9.29e-05 . ctgacccc gcgctaaccc chr15:60878098-60878118 2 9.29e-05 T TTGACCTT CCCACTAGCC chr7:127032756-127032776 5 9.29e-05 CTGA CTGACCCC GGACGGAG chr1:230202773-230202793 10 9.29e-05 CTTTGCTCC CTGACCCC CCT chr19:17420673-17420693 1 9.29e-05 . CTGACCCC ATCCAGGATA chr22:51020959-51020979 9 9.29e-05 CGGAGAGG CTGACCCC TGAC chr16:67700681-67700701 6 9.29e-05 GCCCA CTGACCCC GGCGCAA chr3:141110365-141110385 8 1.39e-04 ATTGCCT TTGACCCC GTCAC chr17:79884596-79884616 13 1.39e-04 GGCTTCACCT TTGACCCC chr17:80489049-80489069 13 1.39e-04 GTTGTAGCCT TTGACCCC chr3:14165931-14165951 5 1.52e-04 CACt gtgacctt ggaccagc chr19:53400907-53400927 4 1.52e-04 GGT GTGACCTT CAGTCCCTG chr12:95467329-95467349 8 1.72e-04 AGAGTTC GTGACCTC TTTCT chr19:44405979-44405999 9 2.12e-04 GCTCGAGG GTGACCCT AGCG chr9:35834849-35834869 10 2.12e-04 CTGTGGCCC CTGACCTG GAA chr2:152144858-152144878 1 2.44e-04 . gtgacccc ggaagaactt chr5:125936615-125936635 2 2.76e-04 C CTGACCCG CCGCTGTGCA chr15:59981494-59981514 10 2.76e-04 CGGCAGCAG CTGACCCG GAC chrX:54208933-54208953 1 3.17e-04 . TTGACCCG GAAGCGGATG chr11:191813-191833 7 3.64e-04 taaccc ctaacccc taaccc chr6:157253383-157253403 5 3.64e-04 CCCT TTAACCTT TGACTCGT chr5:149104183-149104203 11 3.79e-04 AGTTCATAGG TTAACCCT AC chr5:79287071-79287091 1 4.70e-04 . CCGACCTT TACTATCCCG chr2:232826402-232826422 6 5.33e-04 CGCCC GTGACCCG GAAGAGC chr16:47007608-47007628 6 5.77e-04 GAACT TTGACCCA GCGCACG chr17:35716182-35716202 5 6.39e-04 ACCT CCGACCCC GCTCCGGG chr16:30569731-30569751 4 6.39e-04 TAC TCGACCTT TGCCCCTAC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGACCYY MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:211849267-211849287 1.3e-05 3_[+1]_9 chr2:65648077-65648097 1.3e-05 8_[+1]_4 chr22:37260218-37260238 3.3e-05 4_[+1]_8 chr8:144635826-144635846 3.3e-05 1_[+1]_11 chr6:43655528-43655548 3.3e-05 3_[+1]_9 chr3:125153752-125153772 3.3e-05 11_[+1]_1 chr19:50919390-50919410 3.3e-05 11_[+1]_1 chr13:113344151-11334417 3.3e-05 1_[+1]_11 chr4:699175-699195 5.3e-05 11_[+1]_1 chr19:10363175-10363195 5.3e-05 9_[+1]_3 chr8:144816257-144816277 5.3e-05 6_[+1]_6 chr7:95401709-95401729 9.3e-05 4_[+1]_8 chr20:62339270-62339290 9.3e-05 [+1]_12 chr15:60878098-60878118 9.3e-05 1_[+1]_11 chr7:127032756-127032776 9.3e-05 4_[+1]_8 chr1:230202773-230202793 9.3e-05 9_[+1]_3 chr19:17420673-17420693 9.3e-05 [+1]_12 chr22:51020959-51020979 9.3e-05 8_[+1]_4 chr16:67700681-67700701 9.3e-05 5_[+1]_7 chr3:141110365-141110385 0.00014 7_[+1]_5 chr17:79884596-79884616 0.00014 12_[+1] chr17:80489049-80489069 0.00014 12_[+1] chr3:14165931-14165951 0.00015 4_[+1]_8 chr19:53400907-53400927 0.00015 3_[+1]_9 chr12:95467329-95467349 0.00017 7_[+1]_5 chr19:44405979-44405999 0.00021 8_[+1]_4 chr9:35834849-35834869 0.00021 9_[+1]_3 chr2:152144858-152144878 0.00024 [+1]_12 chr5:125936615-125936635 0.00028 1_[+1]_11 chr15:59981494-59981514 0.00028 9_[+1]_3 chrX:54208933-54208953 0.00032 [+1]_12 chr11:191813-191833 0.00036 6_[+1]_6 chr6:157253383-157253403 0.00036 4_[+1]_8 chr5:149104183-149104203 0.00038 10_[+1]_2 chr5:79287071-79287091 0.00047 [+1]_12 chr2:232826402-232826422 0.00053 5_[+1]_7 chr16:47007608-47007628 0.00058 5_[+1]_7 chr17:35716182-35716202 0.00064 4_[+1]_8 chr16:30569731-30569751 0.00064 3_[+1]_9 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGACCYY MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTGACCYY width=8 seqs=39 chr1:211849267-211849287 ( 4) CTGACCTT 1 chr2:65648077-65648097 ( 9) CTGACCTT 1 chr22:37260218-37260238 ( 5) CTGACCTC 1 chr8:144635826-144635846 ( 2) CTGACCTC 1 chr6:43655528-43655548 ( 4) CTGACCTC 1 chr3:125153752-125153772 ( 12) CTGACCTC 1 chr19:50919390-50919410 ( 12) CTGACCTC 1 chr13:113344151-11334417 ( 2) CTGACCTC 1 chr4:699175-699195 ( 12) CTGACCCT 1 chr19:10363175-10363195 ( 10) CTGACCCT 1 chr8:144816257-144816277 ( 7) CTGACCCT 1 chr7:95401709-95401729 ( 5) TTGACCTT 1 chr20:62339270-62339290 ( 1) CTGACCCC 1 chr15:60878098-60878118 ( 2) TTGACCTT 1 chr7:127032756-127032776 ( 5) CTGACCCC 1 chr1:230202773-230202793 ( 10) CTGACCCC 1 chr19:17420673-17420693 ( 1) CTGACCCC 1 chr22:51020959-51020979 ( 9) CTGACCCC 1 chr16:67700681-67700701 ( 6) CTGACCCC 1 chr3:141110365-141110385 ( 8) TTGACCCC 1 chr17:79884596-79884616 ( 13) TTGACCCC 1 chr17:80489049-80489069 ( 13) TTGACCCC 1 chr3:14165931-14165951 ( 5) GTGACCTT 1 chr19:53400907-53400927 ( 4) GTGACCTT 1 chr12:95467329-95467349 ( 8) GTGACCTC 1 chr19:44405979-44405999 ( 9) GTGACCCT 1 chr9:35834849-35834869 ( 10) CTGACCTG 1 chr2:152144858-152144878 ( 1) GTGACCCC 1 chr5:125936615-125936635 ( 2) CTGACCCG 1 chr15:59981494-59981514 ( 10) CTGACCCG 1 chrX:54208933-54208953 ( 1) TTGACCCG 1 chr11:191813-191833 ( 7) CTAACCCC 1 chr6:157253383-157253403 ( 5) TTAACCTT 1 chr5:149104183-149104203 ( 11) TTAACCCT 1 chr5:79287071-79287091 ( 1) CCGACCTT 1 chr2:232826402-232826422 ( 6) GTGACCCG 1 chr16:47007608-47007628 ( 6) TTGACCCA 1 chr17:35716182-35716202 ( 5) CCGACCCC 1 chr16:30569731-30569751 ( 4) TCGACCTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGACCYY MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 7.29248 E= 1.2e-022 -1193 93 -101 38 -1193 -200 -1193 223 -125 -1193 157 -1193 245 -1193 -1193 -1193 -1193 169 -1193 -1193 -1193 169 -1193 -1193 -1193 87 -1193 115 -283 66 -128 87 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGACCYY MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 39 E= 1.2e-022 0.000000 0.589744 0.153846 0.256410 0.000000 0.076923 0.000000 0.923077 0.076923 0.000000 0.923077 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.564103 0.000000 0.435897 0.025641 0.487179 0.128205 0.358974 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGACCYY MEME-1 regular expression -------------------------------------------------------------------------------- [CT]TGACC[CT][CT] -------------------------------------------------------------------------------- Time 1.87 secs. ******************************************************************************** ******************************************************************************** MOTIF CTTCCGGG MEME-2 width = 8 sites = 19 llr = 157 E-value = 7.1e-005 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTTCCGGG MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::::2:3: pos.-specific C 7::a8::: probability G 3::::979 matrix T :aa::1:1 bits 2.4 ** 2.2 ** 2.0 ** 1.7 *** Relative 1.5 *** Entropy 1.2 ***** * (12.0 bits) 1.0 ******* 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CTTCCGGG consensus G A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGG MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:95538469-95538489 11 3.44e-05 ATGCGTCCAA CTTCCGGG GA chr16:74330394-74330414 10 3.44e-05 AGTGAACTT CTTCCGGG TGG chr5:64920815-64920835 11 3.44e-05 TTTCCGTTTC CTTCCGGG GC chr4:41937143-41937163 12 3.44e-05 GAAAGGAGCA CTTCCGGG T chr5:143550214-143550234 5 3.44e-05 ACGG CTTCCGGG GCACGCCC chr15:55790615-55790635 1 3.44e-05 . CTTCCGGG TCAGGCCGGC chr9:134406648-134406668 13 3.44e-05 GGAGCGATCA CTTCCGGG chr2:175260439-175260459 11 5.47e-05 CAAGGGGGAA CTTCCGAG AT chr10:103348011-10334803 6 5.47e-05 AATAG CTTCCGAG TCAGCCG chrX:1571460-1571480 1 8.94e-05 . GTTCCGGG TCACTCTCCC chr16:4850545-4850565 8 8.94e-05 GCTGGTT GTTCCGGG GCATC chr16:12070495-12070515 8 8.94e-05 GGTTTAC GTTCCGGG TCGGC chr7:39605977-39605997 5 1.86e-04 GGCG CTTCCGGT GGCCTGCG chr16:4401265-4401285 5 1.86e-04 CCGA CTTCCTGG CCCCGCGG chr19:51963883-51963903 8 1.86e-04 ctgtttg cttcctgg acaaa chr12:498815-498835 8 1.86e-04 GGTTGTG CTTCCGGT GAGGA chr16:89572037-89572057 4 2.88e-04 AGA GTTCAGAG GGCTGAGGA chr17:75446610-75446630 9 2.88e-04 TCACTTGG GTTCAGAG GTCG chr16:30640198-30640218 4 2.88e-04 gta gttcagag ggaagaggt -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGG MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:95538469-95538489 3.4e-05 10_[+2]_2 chr16:74330394-74330414 3.4e-05 9_[+2]_3 chr5:64920815-64920835 3.4e-05 10_[+2]_2 chr4:41937143-41937163 3.4e-05 11_[+2]_1 chr5:143550214-143550234 3.4e-05 4_[+2]_8 chr15:55790615-55790635 3.4e-05 [+2]_12 chr9:134406648-134406668 3.4e-05 12_[+2] chr2:175260439-175260459 5.5e-05 10_[+2]_2 chr10:103348011-10334803 5.5e-05 5_[+2]_7 chrX:1571460-1571480 8.9e-05 [+2]_12 chr16:4850545-4850565 8.9e-05 7_[+2]_5 chr16:12070495-12070515 8.9e-05 7_[+2]_5 chr7:39605977-39605997 0.00019 4_[+2]_8 chr16:4401265-4401285 0.00019 4_[+2]_8 chr19:51963883-51963903 0.00019 7_[+2]_5 chr12:498815-498835 0.00019 7_[+2]_5 chr16:89572037-89572057 0.00029 3_[+2]_9 chr17:75446610-75446630 0.00029 8_[+2]_4 chr16:30640198-30640218 0.00029 3_[+2]_9 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGG MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTTCCGGG width=8 seqs=19 chr1:95538469-95538489 ( 11) CTTCCGGG 1 chr16:74330394-74330414 ( 10) CTTCCGGG 1 chr5:64920815-64920835 ( 11) CTTCCGGG 1 chr4:41937143-41937163 ( 12) CTTCCGGG 1 chr5:143550214-143550234 ( 5) CTTCCGGG 1 chr15:55790615-55790635 ( 1) CTTCCGGG 1 chr9:134406648-134406668 ( 13) CTTCCGGG 1 chr2:175260439-175260459 ( 11) CTTCCGAG 1 chr10:103348011-10334803 ( 6) CTTCCGAG 1 chrX:1571460-1571480 ( 1) GTTCCGGG 1 chr16:4850545-4850565 ( 8) GTTCCGGG 1 chr16:12070495-12070515 ( 8) GTTCCGGG 1 chr7:39605977-39605997 ( 5) CTTCCGGT 1 chr16:4401265-4401285 ( 5) CTTCCTGG 1 chr19:51963883-51963903 ( 8) CTTCCTGG 1 chr12:498815-498835 ( 8) CTTCCGGT 1 chr16:89572037-89572057 ( 4) GTTCAGAG 1 chr17:75446610-75446630 ( 9) GTTCAGAG 1 chr16:30640198-30640218 ( 4) GTTCAGAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGG MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 7.60572 E= 7.1e-005 -1089 115 2 -1089 -1089 -1089 -1089 234 -1089 -1089 -1089 234 -1089 169 -1089 -1089 -21 145 -1089 -1089 -1089 -1089 152 -90 52 -1089 124 -1089 -1089 -1089 152 -90 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGG MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 19 E= 7.1e-005 0.000000 0.684211 0.315789 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.157895 0.842105 0.000000 0.000000 0.000000 0.000000 0.894737 0.105263 0.263158 0.000000 0.736842 0.000000 0.000000 0.000000 0.894737 0.105263 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGG MEME-2 regular expression -------------------------------------------------------------------------------- [CG]TTCCG[GA]G -------------------------------------------------------------------------------- Time 2.69 secs. ******************************************************************************** ******************************************************************************** MOTIF CCCGGAAG MEME-3 width = 8 sites = 20 llr = 155 E-value = 8.1e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCCGGAAG MEME-3 Description -------------------------------------------------------------------------------- Simplified A 1:2::a82 pos.-specific C 799::::1 probability G 2::aa::8 matrix T 11::::21 bits 2.4 * 2.2 * 2.0 * 1.7 **** Relative 1.5 **** Entropy 1.2 ****** (11.2 bits) 1.0 ****** 0.7 ******* 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CCCGGAAG consensus G T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCGGAAG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr14:35761584-35761604 1 2.97e-05 . CCCGGAAG CAGTCGCTGC chr1:168148108-168148128 7 2.97e-05 ACTAGT CCCGGAAG CAAAAA chr12:50794585-50794605 10 2.97e-05 TTCCCTAGA CCCGGAAG CAG chr1:213224564-213224584 1 2.97e-05 . CCCGGAAG CTTCTCTGCT chr17:80009766-80009786 2 2.97e-05 C CCCGGAAG TGGACGGCAC chrX:69353756-69353776 4 4.72e-05 GAC CCCGGAAA AGAGATCTT chr14:75593766-75593786 2 4.72e-05 A CCCGGAAA CAGTTCTCTG chr7:97601679-97601699 4 6.48e-05 CGA CCAGGAAG AAGAACCCG chr10:89264610-89264630 8 9.47e-05 CTCCGGA GCCGGAAG CTGGG chr8:130952054-130952074 3 1.27e-04 GA CCCGGATG TACAGGGTAA chr1:28415125-28415145 4 1.27e-04 TGA CCCGGATG CGCATCGCT chr10:103815532-10381555 2 1.46e-04 C CTCGGAAG CCAGAAGGCC chr5:114598573-114598593 4 2.11e-04 CGA CCCGGAAT CAGTGCCCG chr20:34287274-34287294 13 2.11e-04 TGCCCGGCGC TCCGGAAG chr12:96252682-96252702 10 2.66e-04 ATCACAGAG GCAGGAAG GGC chr8:124286555-124286575 3 3.14e-04 AA CCCGGAAC CGCTCGGCGG chr19:14528833-14528853 2 3.57e-04 a gccggatg tgcttgcttg chr4:108641512-108641532 2 3.57e-04 C CTCGGAAA TGGGTCCGGG chr11:118868850-11886887 5 3.57e-04 GGCC GCCGGATG GCGTAGGA chr19:18335077-18335097 10 4.40e-04 GCGGCACCG ACAGGAAG ACA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCGGAAG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr14:35761584-35761604 3e-05 [+3]_12 chr1:168148108-168148128 3e-05 6_[+3]_6 chr12:50794585-50794605 3e-05 9_[+3]_3 chr1:213224564-213224584 3e-05 [+3]_12 chr17:80009766-80009786 3e-05 1_[+3]_11 chrX:69353756-69353776 4.7e-05 3_[+3]_9 chr14:75593766-75593786 4.7e-05 1_[+3]_11 chr7:97601679-97601699 6.5e-05 3_[+3]_9 chr10:89264610-89264630 9.5e-05 7_[+3]_5 chr8:130952054-130952074 0.00013 2_[+3]_10 chr1:28415125-28415145 0.00013 3_[+3]_9 chr10:103815532-10381555 0.00015 1_[+3]_11 chr5:114598573-114598593 0.00021 3_[+3]_9 chr20:34287274-34287294 0.00021 12_[+3] chr12:96252682-96252702 0.00027 9_[+3]_3 chr8:124286555-124286575 0.00031 2_[+3]_10 chr19:14528833-14528853 0.00036 1_[+3]_11 chr4:108641512-108641532 0.00036 1_[+3]_11 chr11:118868850-11886887 0.00036 4_[+3]_8 chr19:18335077-18335097 0.00044 9_[+3]_3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCGGAAG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCCGGAAG width=8 seqs=20 chr14:35761584-35761604 ( 1) CCCGGAAG 1 chr1:168148108-168148128 ( 7) CCCGGAAG 1 chr12:50794585-50794605 ( 10) CCCGGAAG 1 chr1:213224564-213224584 ( 1) CCCGGAAG 1 chr17:80009766-80009786 ( 2) CCCGGAAG 1 chrX:69353756-69353776 ( 4) CCCGGAAA 1 chr14:75593766-75593786 ( 2) CCCGGAAA 1 chr7:97601679-97601699 ( 4) CCAGGAAG 1 chr10:89264610-89264630 ( 8) GCCGGAAG 1 chr8:130952054-130952074 ( 3) CCCGGATG 1 chr1:28415125-28415145 ( 4) CCCGGATG 1 chr10:103815532-10381555 ( 2) CTCGGAAG 1 chr5:114598573-114598593 ( 4) CCCGGAAT 1 chr20:34287274-34287294 ( 13) TCCGGAAG 1 chr12:96252682-96252702 ( 10) GCAGGAAG 1 chr8:124286555-124286575 ( 3) CCCGGAAC 1 chr19:14528833-14528853 ( 2) GCCGGATG 1 chr4:108641512-108641532 ( 2) CTCGGAAA 1 chr11:118868850-11886887 ( 5) GCCGGATG 1 chr19:18335077-18335097 ( 10) ACAGGAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCGGAAG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 7.58836 E= 8.1e-002 -187 118 -64 -198 -1097 154 -1097 -98 -29 146 -1097 -1097 -1097 -1097 168 -1097 -1097 -1097 168 -1097 245 -1097 -1097 -1097 213 -1097 -1097 2 -29 -262 127 -198 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCGGAAG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 20 E= 8.1e-002 0.050000 0.700000 0.200000 0.050000 0.000000 0.900000 0.000000 0.100000 0.150000 0.850000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.200000 0.150000 0.050000 0.750000 0.050000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCGGAAG MEME-3 regular expression -------------------------------------------------------------------------------- [CG]CCGGA[AT]G -------------------------------------------------------------------------------- Time 5.48 secs. ******************************************************************************** ******************************************************************************** MOTIF ARRGGTCA MEME-4 width = 8 sites = 24 llr = 170 E-value = 4.3e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif ARRGGTCA MEME-4 Description -------------------------------------------------------------------------------- Simplified A 566:2::a pos.-specific C 3:::::9: probability G 144a83:: matrix T 1::::71: bits 2.4 2.2 * 2.0 * 1.7 * * Relative 1.5 * * Entropy 1.2 *** *** (10.2 bits) 1.0 ******* 0.7 ******* 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AAAGGTCA consensus CGG AG sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARRGGTCA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:47013137-47013157 5 6.60e-06 ATTC AAAGGTCA AAGTACCT chrX:122866912-122866932 7 3.29e-05 CGAGCG AAGGGTCA AAGGGG chr1:11862840-11862860 13 5.45e-05 CTGCCGGGTT AAAGGGCA chr2:153573983-153574003 13 5.87e-05 CACTGGGGCT AAAGGTTA chr17:61920560-61920580 4 6.58e-05 GTC TAAGGTCA CTTAGGGGC chr19:49136822-49136842 4 1.11e-04 GGG CAAGATCA GCTGGGTCG chr18:54318861-54318881 13 1.11e-04 CGTGGAGGTC AGGGGTCA chr15:48623616-48623636 1 2.02e-04 . CGAGGTCA TGTTCCCAGG chr4:47916817-47916837 12 2.02e-04 GGGAGGGGTC GAAGGTCA T chr16:85045147-85045167 3 2.02e-04 GA CGAGGTCA GTGACGTCAC chr17:1755830-1755850 13 2.02e-04 ggcagagggc agagggca chr13:50018495-50018515 7 2.02e-04 CCGGCC AGAGGGCA CCTGCG chr5:67721061-67721081 11 2.20e-04 gtcaagggtg aaagttca ag chr15:102521016-10252103 11 2.20e-04 gttaggggtt aagggtta ag chr3:119012164-119012184 4 3.03e-04 TGT TAAGGTTA CATAGAGAG chr13:41837692-41837712 12 3.53e-04 CCGACAAACC CGAGATCA C chr4:41937143-41937163 4 3.53e-04 TGA AAGGAGCA CTTCCGGGT chr19:51403046-51403066 5 3.53e-04 tgga aaggagca gtaacttc chr12:70637175-70637195 11 3.68e-04 GTCAGAGGGT AAAGGTCT TG chr6:24774998-24775018 1 4.93e-04 . CAAGAGCA GGGTCGGAGG chr6:108616625-108616645 10 4.93e-04 TTTCATTTT GAGGGTCA GAG chr22:47158758-47158778 13 4.93e-04 AGGGCCAGGT CGGGGTCA chr16:30392838-30392858 5 4.93e-04 GGGC AGGGGGCA AGGCTAGC chr19:1068299-1068319 3 5.55e-04 TG TGGGGTCA GGGTGATGGT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARRGGTCA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:47013137-47013157 6.6e-06 4_[+4]_8 chrX:122866912-122866932 3.3e-05 6_[+4]_6 chr1:11862840-11862860 5.5e-05 12_[+4] chr2:153573983-153574003 5.9e-05 12_[+4] chr17:61920560-61920580 6.6e-05 3_[+4]_9 chr19:49136822-49136842 0.00011 3_[+4]_9 chr18:54318861-54318881 0.00011 12_[+4] chr15:48623616-48623636 0.0002 [+4]_12 chr4:47916817-47916837 0.0002 11_[+4]_1 chr16:85045147-85045167 0.0002 2_[+4]_10 chr17:1755830-1755850 0.0002 12_[+4] chr13:50018495-50018515 0.0002 6_[+4]_6 chr5:67721061-67721081 0.00022 10_[+4]_2 chr15:102521016-10252103 0.00022 10_[+4]_2 chr3:119012164-119012184 0.0003 3_[+4]_9 chr13:41837692-41837712 0.00035 11_[+4]_1 chr4:41937143-41937163 0.00035 3_[+4]_9 chr19:51403046-51403066 0.00035 4_[+4]_8 chr12:70637175-70637195 0.00037 10_[+4]_2 chr6:24774998-24775018 0.00049 [+4]_12 chr6:108616625-108616645 0.00049 9_[+4]_3 chr22:47158758-47158778 0.00049 12_[+4] chr16:30392838-30392858 0.00049 4_[+4]_8 chr19:1068299-1068319 0.00055 2_[+4]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARRGGTCA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ARRGGTCA width=8 seqs=24 chr4:47013137-47013157 ( 5) AAAGGTCA 1 chrX:122866912-122866932 ( 7) AAGGGTCA 1 chr1:11862840-11862860 ( 13) AAAGGGCA 1 chr2:153573983-153574003 ( 13) AAAGGTTA 1 chr17:61920560-61920580 ( 4) TAAGGTCA 1 chr19:49136822-49136842 ( 4) CAAGATCA 1 chr18:54318861-54318881 ( 13) AGGGGTCA 1 chr15:48623616-48623636 ( 1) CGAGGTCA 1 chr4:47916817-47916837 ( 12) GAAGGTCA 1 chr16:85045147-85045167 ( 3) CGAGGTCA 1 chr17:1755830-1755850 ( 13) AGAGGGCA 1 chr13:50018495-50018515 ( 7) AGAGGGCA 1 chr5:67721061-67721081 ( 11) AAAGTTCA 1 chr15:102521016-10252103 ( 11) AAGGGTTA 1 chr3:119012164-119012184 ( 4) TAAGGTTA 1 chr13:41837692-41837712 ( 12) CGAGATCA 1 chr4:41937143-41937163 ( 4) AAGGAGCA 1 chr19:51403046-51403066 ( 5) AAGGAGCA 1 chr12:70637175-70637195 ( 11) AAAGGTCT 1 chr6:24774998-24775018 ( 1) CAAGAGCA 1 chr6:108616625-108616645 ( 10) GAGGGTCA 1 chr22:47158758-47158778 ( 13) CGGGGTCA 1 chr16:30392838-30392858 ( 5) AGGGGGCA 1 chr19:1068299-1068319 ( 3) TGGGGTCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARRGGTCA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.17582 E= 4.3e+001 156 -31 -190 -66 177 -1123 27 -1123 177 -1123 27 -1123 -1123 -1123 168 -1123 19 -1123 127 -224 -1123 -1123 -9 185 -1123 150 -1123 -66 239 -1123 -1123 -224 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARRGGTCA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 24 E= 4.3e+001 0.541667 0.250000 0.083333 0.125000 0.625000 0.000000 0.375000 0.000000 0.625000 0.000000 0.375000 0.000000 0.000000 0.000000 1.000000 0.000000 0.208333 0.000000 0.750000 0.041667 0.000000 0.000000 0.291667 0.708333 0.000000 0.875000 0.000000 0.125000 0.958333 0.000000 0.000000 0.041667 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ARRGGTCA MEME-4 regular expression -------------------------------------------------------------------------------- [AC][AG][AG]G[GA][TG]CA -------------------------------------------------------------------------------- Time 8.57 secs. ******************************************************************************** ******************************************************************************** MOTIF AWAASAAA MEME-5 width = 8 sites = 2 llr = 23 E-value = 1.5e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif AWAASAAA MEME-5 Description -------------------------------------------------------------------------------- Simplified A a5aa:aaa pos.-specific C ::::5::: probability G ::::5::: matrix T :5:::::: bits 2.4 * ** *** 2.2 * ** *** 2.0 * ** *** 1.7 * ** *** Relative 1.5 **** *** Entropy 1.2 **** *** (16.8 bits) 1.0 **** *** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AAAACAAA consensus T G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AWAASAAA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:151038862-151038882 4 4.26e-06 ATG AAAACAAA CGGCGGCCG chr19:633210-633230 8 8.85e-06 AGGCTGC ATAAGAAA CCACG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AWAASAAA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:151038862-151038882 4.3e-06 3_[+5]_9 chr19:633210-633230 8.8e-06 7_[+5]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AWAASAAA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AWAASAAA width=8 seqs=2 chr7:151038862-151038882 ( 4) AAAACAAA 1 chr19:633210-633230 ( 8) ATAAGAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AWAASAAA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 10.6653 E= 1.5e+003 244 -765 -765 -765 145 -765 -765 134 244 -765 -765 -765 244 -765 -765 -765 -765 69 68 -765 244 -765 -765 -765 244 -765 -765 -765 244 -765 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AWAASAAA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 1.5e+003 1.000000 0.000000 0.000000 0.000000 0.500000 0.000000 0.000000 0.500000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.500000 0.500000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AWAASAAA MEME-5 regular expression -------------------------------------------------------------------------------- A[AT]AA[CG]AAA -------------------------------------------------------------------------------- Time 11.70 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:22019369-22019389 9.87e-01 20 chr11:118868850-11886887 2.22e-01 20 chr8:182427-182447 6.92e-01 20 chr13:113344151-11334417 9.65e-02 1_[+1(3.30e-05)]_11 chr8:144816257-144816277 8.92e-02 6_[+1(5.31e-05)]_6 chr17:80009766-80009786 2.74e-02 1_[+3(2.97e-05)]_11 chr19:1068299-1068319 3.66e-02 20 chr18:54318861-54318881 3.22e-02 20 chr16:30392838-30392858 1.49e-01 20 chr5:176981616-176981636 9.85e-01 20 chr16:30710525-30710545 2.56e-02 20 chr8:57906373-57906393 4.17e-01 20 chr1:27934043-27934063 3.84e-01 20 chr6:372801-372821 9.84e-01 20 chr17:80489049-80489069 1.39e-01 20 chr10:35625446-35625466 9.95e-01 20 chr9:72374983-72375003 8.94e-01 20 chr19:38806389-38806409 2.61e-01 20 chr16:12070495-12070515 3.00e-02 7_[+2(8.94e-05)]_5 chr9:134406648-134406668 1.55e-02 12_[+2(3.44e-05)] chr10:103815532-10381555 5.17e-02 20 chr12:498815-498835 1.11e-01 20 chr1:19811967-19811987 9.26e-01 20 chr3:14989125-14989145 6.99e-01 20 chr3:37217886-37217906 8.92e-01 20 chr9:136223359-136223379 3.68e-01 20 chr8:124286555-124286575 1.39e-01 20 chr16:30569731-30569751 4.33e-01 20 chrX:103401975-103401995 2.74e-02 20 chr4:108641512-108641532 1.59e-02 20 chr11:64073603-64073623 5.14e-01 20 chr12:48551272-48551292 9.73e-01 20 chr3:119395992-119396012 5.43e-01 20 chr7:151038862-151038882 1.86e-02 3_[+5(4.26e-06)]_9 chr19:50919390-50919410 5.02e-02 11_[+1(3.30e-05)]_1 chr7:6865950-6865970 8.62e-02 20 chr4:658000-658020 5.35e-01 20 chr1:11862840-11862860 1.03e-03 12_[+4(5.45e-05)] chr6:169852619-169852639 7.91e-01 20 chr9:37568705-37568725 1.25e-01 20 chr1:3663922-3663942 1.96e-01 20 chr16:67700681-67700701 9.44e-02 5_[+1(9.29e-05)]_7 chr22:47158758-47158778 1.18e-01 20 chr19:10197316-10197336 8.45e-02 20 chr1:762830-762850 2.69e-01 20 chr12:70637175-70637195 9.79e-02 20 chr7:5270597-5270617 1.08e-01 20 chr19:51963883-51963903 3.61e-02 20 chr22:51020959-51020979 9.84e-02 8_[+1(9.29e-05)]_4 chr2:175901468-175901488 5.19e-01 20 chr1:78245298-78245318 9.86e-01 20 chr1:110752561-110752581 9.17e-01 20 chr11:64027205-64027225 9.18e-01 20 chr22:43659373-43659393 4.85e-01 20 chr3:33138080-33138100 6.33e-01 20 chr1:233085998-233086018 2.15e-01 20 chr22:51066510-51066530 5.39e-01 20 chrX:153775790-153775810 9.86e-01 20 chr16:47007608-47007628 3.05e-01 20 chr19:17420673-17420693 1.07e-03 [+1(9.29e-05)]_12 chr14:95623969-95623989 9.93e-01 20 chr7:76751706-76751726 8.64e-01 20 chr21:45432649-45432669 6.69e-01 20 chr16:4850545-4850565 2.80e-02 7_[+2(8.94e-05)]_5 chr9:35834849-35834869 1.37e-01 20 chr3:125153752-125153772 5.68e-02 11_[+1(3.30e-05)]_1 chr14:70883804-70883824 3.29e-01 20 chr10:21814827-21814847 6.25e-01 20 chr19:2236828-2236848 9.28e-01 20 chr15:59981494-59981514 1.25e-01 20 chr4:57333738-57333758 1.26e-01 20 chr11:134123361-13412338 7.05e-01 20 chr20:42087859-42087879 9.99e-01 20 chr20:34287274-34287294 5.15e-02 20 chr12:95467329-95467349 4.63e-02 20 chr4:144106103-144106123 2.74e-01 20 chr10:89264610-89264630 1.88e-02 7_[+3(9.47e-05)]_5 chr6:108616625-108616645 8.72e-02 20 chr5:114598573-114598593 6.40e-02 20 chr12:6665292-6665312 4.76e-01 20 chr6:146136037-146136057 6.99e-01 20 chr19:1173746-1173766 2.00e-01 20 chr12:133532917-13353293 1.07e-01 20 chr19:14229141-14229161 7.19e-01 20 chr1:151138036-151138056 3.22e-01 20 chr15:102521016-10252103 3.61e-02 20 chr6:43655528-43655548 5.64e-02 3_[+1(3.30e-05)]_9 chr17:48799039-48799059 4.90e-01 20 chr1:155179064-155179084 1.82e-01 20 chr7:72971632-72971652 9.48e-01 20 chr6:96025652-96025672 7.92e-01 20 chr17:38083183-38083203 6.66e-01 20 chr10:99185823-99185843 9.80e-01 20 chr4:47013137-47013157 3.07e-03 4_[+4(6.60e-06)]_8 chr12:96252682-96252702 1.58e-02 20 chr17:37027876-37027896 4.54e-01 20 chr2:207139617-207139637 8.60e-01 20 chr15:67835000-67835020 9.14e-01 20 chr19:18335077-18335097 7.70e-02 20 chr9:125675619-125675639 9.03e-01 20 chr5:79287071-79287091 2.24e-01 20 chr19:14528833-14528853 1.10e-01 20 chr13:50018495-50018515 5.25e-02 20 chr19:51403046-51403066 1.19e-02 20 chr16:31128975-31128995 6.24e-01 20 chr1:230202773-230202793 6.62e-02 9_[+1(9.29e-05)]_3 chr11:62495902-62495922 3.87e-01 20 chr19:10363175-10363195 4.72e-03 9_[+1(5.31e-05)]_3 chr19:35168203-35168223 9.23e-02 20 chr22:38349675-38349695 5.31e-01 20 chr15:55790615-55790635 8.86e-03 [+2(3.44e-05)]_12 chr19:37178390-37178410 6.40e-01 20 chr10:103348011-10334803 5.27e-02 5_[+2(5.47e-05)]_7 chr15:82555082-82555102 5.72e-01 20 chr5:67721061-67721081 6.02e-02 20 chrX:122866912-122866932 4.01e-02 6_[+4(3.29e-05)]_6 chr7:97601679-97601699 3.46e-03 3_[+3(6.48e-05)]_9 chr14:75593766-75593786 1.55e-02 1_[+3(4.72e-05)]_11 chr7:39663161-39663181 3.88e-01 20 chr5:143550214-143550234 2.68e-02 4_[+2(3.44e-05)]_8 chr2:232826402-232826422 1.94e-03 9_[+3(2.97e-05)]_3 chr9:129567270-129567290 2.93e-01 20 chrX:48595713-48595733 3.13e-01 20 chr1:213224564-213224584 2.68e-02 [+3(2.97e-05)]_12 chr2:3381145-3381165 8.19e-01 20 chr2:73441394-73441414 4.97e-01 20 chrX:54208933-54208953 1.12e-03 4_[+3(2.97e-05)]_8 chr18:22006583-22006603 9.73e-01 20 chr7:135662078-135662098 2.19e-01 20 chr12:50794585-50794605 2.86e-03 9_[+3(2.97e-05)]_3 chr19:44405979-44405999 2.63e-02 20 chr9:116036917-116036937 3.26e-01 20 chrX:69353756-69353776 4.26e-05 3_[+3(4.72e-05)]_9 chr16:4401265-4401285 4.05e-02 20 chr7:127032756-127032776 1.63e-02 4_[+1(9.29e-05)]_8 chr17:61920560-61920580 1.93e-02 3_[+4(6.58e-05)]_9 chr16:30640198-30640218 1.11e-02 20 chr10:22994091-22994111 1.60e-01 20 chr15:60878098-60878118 5.84e-02 1_[+1(9.29e-05)]_11 chr19:40315364-40315384 3.83e-01 20 chr19:633210-633230 3.14e-03 7_[+5(8.85e-06)]_5 chr12:69864155-69864175 1.18e-01 20 chr19:6393224-6393244 7.43e-01 20 chr2:175260439-175260459 8.80e-03 10_[+2(5.47e-05)]_2 chr7:39605977-39605997 5.20e-02 20 chr4:41937143-41937163 8.42e-04 11_[+2(3.44e-05)]_1 chr2:27994602-27994622 9.20e-01 20 chr2:207024484-207024504 2.43e-01 20 chr16:30546289-30546309 8.59e-01 20 chr17:46185095-46185115 6.25e-01 20 chrX:1571460-1571480 9.32e-03 [+2(8.94e-05)]_12 chr11:59382764-59382784 3.45e-01 20 chr6:31633708-31633728 6.96e-01 20 chr6:157253383-157253403 2.96e-01 20 chr1:1209226-1209246 5.91e-01 20 chr12:14538485-14538505 1.99e-01 20 chr5:1801520-1801540 8.15e-01 20 chr8:144635826-144635846 8.80e-02 1_[+1(3.30e-05)]_11 chr1:168148108-168148128 8.57e-04 6_[+3(2.97e-05)]_6 chr12:123868250-12386827 6.48e-02 20 chr17:37844290-37844310 1.17e-01 20 chr1:28415125-28415145 1.28e-01 20 chr2:39103089-39103109 9.53e-01 20 chr17:38975431-38975451 3.84e-01 20 chr17:31208259-31208279 4.85e-01 20 chr20:62339270-62339290 1.57e-01 [+1(9.29e-05)]_12 chr12:107168294-10716831 6.10e-01 20 chr19:2328610-2328630 9.02e-01 20 chr2:190648258-190648278 2.04e-01 20 chr19:39616626-39616646 9.75e-01 20 chr20:19997955-19997975 9.93e-01 20 chr2:65648077-65648097 2.71e-02 8_[+1(1.28e-05)]_4 chr14:35761584-35761604 2.92e-02 [+3(2.97e-05)]_12 chr3:178865867-178865887 5.77e-01 20 chr9:140513122-140513142 8.74e-01 20 chr17:80709876-80709896 9.05e-01 20 chr9:95640392-95640412 8.99e-01 20 chr18:55719151-55719171 3.16e-01 20 chr17:35716182-35716202 6.40e-02 20 chr6:99873229-99873249 2.87e-01 20 chr17:79884596-79884616 7.57e-02 20 chr17:75446610-75446630 2.80e-02 20 chrX:2548754-2548774 2.94e-01 20 chr3:37285188-37285208 4.50e-02 20 chr2:152144858-152144878 1.65e-04 5_[+3(2.97e-05)]_7 chr9:138986194-138986214 1.01e-01 20 chr22:31742349-31742369 5.68e-01 20 chr19:53400907-53400927 7.98e-02 20 chr17:1755830-1755850 1.31e-01 20 chr10:75541796-75541816 2.46e-01 20 chr5:154238183-154238203 1.01e-01 20 chr22:37260218-37260238 1.98e-02 4_[+1(3.30e-05)]_8 chr3:14165931-14165951 1.52e-01 20 chr7:44240514-44240534 8.54e-01 20 chr3:119012164-119012184 1.79e-02 20 chr10:89577973-89577993 2.54e-02 20 chr6:24774998-24775018 2.26e-02 20 chr7:95401709-95401729 3.10e-02 4_[+1(9.29e-05)]_8 chr16:85045147-85045167 2.14e-02 20 chr5:64920815-64920835 5.90e-02 10_[+2(3.44e-05)]_2 chr16:89572037-89572057 9.80e-03 20 chr22:43485442-43485462 6.20e-01 20 chr5:78908302-78908322 9.94e-01 20 chr4:47916817-47916837 1.46e-01 20 chr20:34129923-34129943 5.51e-01 20 chr15:48623616-48623636 2.33e-02 20 chr4:1722992-1723012 1.43e-01 20 chr2:159312973-159312993 5.16e-01 20 chr19:41257718-41257738 6.61e-01 20 chrX:153251167-153251187 8.62e-01 20 chr19:51294442-51294462 4.62e-01 20 chr7:102389382-102389402 8.50e-01 20 chr5:14664781-14664801 9.55e-01 20 chr19:11513064-11513084 9.63e-01 20 chr3:49203798-49203818 9.07e-01 20 chr16:74330394-74330414 2.40e-03 9_[+2(3.44e-05)]_3 chr2:231191871-231191891 2.43e-01 20 chr13:41837692-41837712 1.61e-02 20 chr2:44394946-44394966 2.17e-01 20 chr1:101360750-101360770 1.50e-01 20 chr3:141110365-141110385 1.55e-01 20 chr13:107019882-10701990 6.91e-02 20 chrX:46306674-46306694 4.85e-01 20 chr4:699175-699195 7.74e-02 11_[+1(5.31e-05)]_1 chr7:74489602-74489622 7.36e-01 20 chr16:74402129-74402149 8.52e-01 20 chr6:10404882-10404902 3.97e-01 20 chr10:107567851-10756787 6.59e-01 20 chr5:149104183-149104203 4.66e-04 20 chr12:57146197-57146217 7.60e-01 20 chr7:5938271-5938291 9.73e-02 20 chr8:92082550-92082570 8.14e-01 20 chr1:95538469-95538489 2.53e-02 10_[+2(3.44e-05)]_2 chr8:21897310-21897330 5.94e-01 20 chr5:125936615-125936635 2.74e-01 20 chr12:92899872-92899892 4.11e-01 20 chr3:52740091-52740111 3.32e-01 20 chr10:26986522-26986542 3.27e-01 20 chr10:43951143-43951163 9.27e-01 20 chr4:123844225-123844245 9.58e-01 20 chr19:49136822-49136842 2.70e-02 20 chr2:153573983-153574003 2.79e-02 12_[+4(5.87e-05)] chr8:130952054-130952074 5.72e-03 20 chr16:4784282-4784302 8.38e-01 20 chr11:191813-191833 1.95e-01 20 chr1:211849267-211849287 1.41e-02 3_[+1(1.28e-05)]_9 chr8:28747327-28747347 4.59e-02 20 chr19:35865970-35865990 4.95e-01 20 chr13:98854541-98854561 9.90e-01 20 chr11:32605346-32605366 9.22e-01 20 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n09.farnam.hpc.yale.internal ********************************************************************************