******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/MEF2B.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr6:149803399-149803419 1.0000 20 chr1:44784098-44784118 1.0000 20 chr11:69485192-69485212 1.0000 20 chr12:10875291-10875311 1.0000 20 chr17:9828254-9828274 1.0000 20 chr8:23366532-23366552 1.0000 20 chr3:48236092-48236112 1.0000 20 chr21:42741474-42741494 1.0000 20 chr6:160296564-160296584 1.0000 20 chr15:78183714-78183734 1.0000 20 chr16:89041258-89041278 1.0000 20 chr22:30787260-30787280 1.0000 20 chr1:233088822-233088842 1.0000 20 chr10:88731164-88731184 1.0000 20 chr12:131540568-13154058 1.0000 20 chr9:125226361-125226381 1.0000 20 chr12:131455345-13145536 1.0000 20 chr10:1020241-1020261 1.0000 20 chr5:148799584-148799604 1.0000 20 chr7:95083971-95083991 1.0000 20 chr14:24835950-24835970 1.0000 20 chr6:149081056-149081076 1.0000 20 chrX:106953967-106953987 1.0000 20 chr10:71867314-71867334 1.0000 20 chr2:7567591-7567611 1.0000 20 chr6:33138081-33138101 1.0000 20 chr15:99496294-99496314 1.0000 20 chr3:149732693-149732713 1.0000 20 chrX:19881799-19881819 1.0000 20 chr1:26869777-26869797 1.0000 20 chr2:8143027-8143047 1.0000 20 chr15:23188103-23188123 1.0000 20 chr16:57015419-57015439 1.0000 20 chr20:44589050-44589070 1.0000 20 chr13:61821964-61821984 1.0000 20 chr13:31018183-31018203 1.0000 20 chr13:78775722-78775742 1.0000 20 chr6:97243013-97243033 1.0000 20 chr6:41301602-41301622 1.0000 20 chr1:211870858-211870878 1.0000 20 chr17:71278252-71278272 1.0000 20 chr11:5145450-5145470 1.0000 20 chr4:110624828-110624848 1.0000 20 chr1:1107255-1107275 1.0000 20 chr3:69373746-69373766 1.0000 20 chr9:88861862-88861882 1.0000 20 chr5:153900688-153900708 1.0000 20 chr2:30440560-30440580 1.0000 20 chr3:52058009-52058029 1.0000 20 chr9:140013448-140013468 1.0000 20 chr10:52107410-52107430 1.0000 20 chr14:68487800-68487820 1.0000 20 chr19:3172752-3172772 1.0000 20 chr3:171515324-171515344 1.0000 20 chr13:99988068-99988088 1.0000 20 chr1:110198645-110198665 1.0000 20 chr2:96822932-96822952 1.0000 20 chr19:7410875-7410895 1.0000 20 chr22:25966104-25966124 1.0000 20 chr5:7794535-7794555 1.0000 20 chr4:113438242-113438262 1.0000 20 chr5:37185013-37185033 1.0000 20 chr16:58137068-58137088 1.0000 20 chr18:12885780-12885800 1.0000 20 chr1:1373642-1373662 1.0000 20 chr20:47085194-47085214 1.0000 20 chr5:168307086-168307106 1.0000 20 chr2:62369377-62369397 1.0000 20 chr1:24330101-24330121 1.0000 20 chr18:46305212-46305232 1.0000 20 chr16:15850173-15850193 1.0000 20 chr17:43117170-43117190 1.0000 20 chr15:54375913-54375933 1.0000 20 chr1:203142873-203142893 1.0000 20 chr14:33980358-33980378 1.0000 20 chr22:42345696-42345716 1.0000 20 chr9:5583486-5583506 1.0000 20 chr21:37885916-37885936 1.0000 20 chr19:35892601-35892621 1.0000 20 chr17:70509286-70509306 1.0000 20 chr9:107535167-107535187 1.0000 20 chr1:170040760-170040780 1.0000 20 chr1:28503862-28503882 1.0000 20 chr12:110809375-11080939 1.0000 20 chr16:57033966-57033986 1.0000 20 chr4:156681278-156681298 1.0000 20 chr3:184135809-184135829 1.0000 20 chr10:110359251-11035927 1.0000 20 chr1:31950342-31950362 1.0000 20 chr2:20414134-20414154 1.0000 20 chr3:178764544-178764564 1.0000 20 chr5:131836969-131836989 1.0000 20 chr2:6913404-6913424 1.0000 20 chr4:114559588-114559608 1.0000 20 chr6:1575669-1575689 1.0000 20 chr17:61996815-61996835 1.0000 20 chrX:11783020-11783040 1.0000 20 chr16:11836963-11836983 1.0000 20 chr1:8703815-8703835 1.0000 20 chr19:42618305-42618325 1.0000 20 chr12:11933606-11933626 1.0000 20 chr14:33978082-33978102 1.0000 20 chr4:159973676-159973696 1.0000 20 chr4:75994878-75994898 1.0000 20 chr1:32803121-32803141 1.0000 20 chr5:71748179-71748199 1.0000 20 chr12:16084719-16084739 1.0000 20 chr5:132143176-132143196 1.0000 20 chr8:70725809-70725829 1.0000 20 chr17:74816358-74816378 1.0000 20 chr16:90074390-90074410 1.0000 20 chr1:2508227-2508247 1.0000 20 chr8:101457583-101457603 1.0000 20 chr11:125243819-12524383 1.0000 20 chr10:64287244-64287264 1.0000 20 chr17:43539559-43539579 1.0000 20 chr15:31631224-31631244 1.0000 20 chr17:62804933-62804953 1.0000 20 chr9:140172213-140172233 1.0000 20 chr4:83380077-83380097 1.0000 20 chr4:159787108-159787128 1.0000 20 chr16:25051988-25052008 1.0000 20 chr19:10714215-10714235 1.0000 20 chr22:40295262-40295282 1.0000 20 chr16:13646695-13646715 1.0000 20 chr13:32470804-32470824 1.0000 20 chr14:100535936-10053595 1.0000 20 chr5:176937403-176937423 1.0000 20 chr12:29879078-29879098 1.0000 20 chr9:19129975-19129995 1.0000 20 chr1:202134010-202134030 1.0000 20 chr4:116436030-116436050 1.0000 20 chrX:153189651-153189671 1.0000 20 chr9:140162559-140162579 1.0000 20 chr11:60589871-60589891 1.0000 20 chr1:3487471-3487491 1.0000 20 chr9:121292097-121292117 1.0000 20 chr17:72279072-72279092 1.0000 20 chr3:36933283-36933303 1.0000 20 chr12:739358-739378 1.0000 20 chr19:35975718-35975738 1.0000 20 chr11:69025950-69025970 1.0000 20 chr17:40706987-40707007 1.0000 20 chr10:125974665-12597468 1.0000 20 chr8:142106737-142106757 1.0000 20 chr1:25848902-25848922 1.0000 20 chr2:204553664-204553684 1.0000 20 chr1:17421291-17421311 1.0000 20 chr18:39768112-39768132 1.0000 20 chr4:156588700-156588720 1.0000 20 chr11:46504831-46504851 1.0000 20 chr1:25071559-25071579 1.0000 20 chr8:96103648-96103668 1.0000 20 chr16:18980718-18980738 1.0000 20 chr17:62009763-62009783 1.0000 20 chr5:150005810-150005830 1.0000 20 chr4:7256621-7256641 1.0000 20 chr9:112891441-112891461 1.0000 20 chr19:18281866-18281886 1.0000 20 chr11:61735806-61735826 1.0000 20 chr9:131406137-131406157 1.0000 20 chr10:12306670-12306690 1.0000 20 chr19:18768645-18768665 1.0000 20 chr5:137799755-137799775 1.0000 20 chr1:198571211-198571231 1.0000 20 chr1:205283053-205283073 1.0000 20 chr7:116871042-116871062 1.0000 20 chr7:1126266-1126286 1.0000 20 chr11:58414830-58414850 1.0000 20 chr6:6546940-6546960 1.0000 20 chr6:89203657-89203677 1.0000 20 chr11:64405665-64405685 1.0000 20 chr17:17595435-17595455 1.0000 20 chr11:13338204-13338224 1.0000 20 chr19:11692857-11692877 1.0000 20 chr5:58187303-58187323 1.0000 20 chr7:31932080-31932100 1.0000 20 chr10:82349821-82349841 1.0000 20 chr5:76886257-76886277 1.0000 20 chr1:27425645-27425665 1.0000 20 chr6:76445832-76445852 1.0000 20 chr6:15254458-15254478 1.0000 20 chr17:74478108-74478128 1.0000 20 chr7:148272840-148272860 1.0000 20 chr4:113211630-113211650 1.0000 20 chr5:111922528-111922548 1.0000 20 chr1:840838-840858 1.0000 20 chr16:11043480-11043500 1.0000 20 chr4:38762695-38762715 1.0000 20 chr7:120496947-120496967 1.0000 20 chr20:61585327-61585347 1.0000 20 chr13:40634646-40634666 1.0000 20 chr10:1496792-1496812 1.0000 20 chr8:70730602-70730622 1.0000 20 chr2:153422878-153422898 1.0000 20 chr20:10340553-10340573 1.0000 20 chr8:135612652-135612672 1.0000 20 chr1:45772069-45772089 1.0000 20 chr6:12354924-12354944 1.0000 20 chrX:78515072-78515092 1.0000 20 chr19:2089563-2089583 1.0000 20 chr10:25218280-25218300 1.0000 20 chr8:22740551-22740571 1.0000 20 chr14:60687066-60687086 1.0000 20 chr11:67808218-67808238 1.0000 20 chr20:61641120-61641140 1.0000 20 chr1:1603360-1603380 1.0000 20 chr3:126935337-126935357 1.0000 20 chr1:109655474-109655494 1.0000 20 chr2:242755107-242755127 1.0000 20 chr16:28942221-28942241 1.0000 20 chr7:151451342-151451362 1.0000 20 chr4:5707588-5707608 1.0000 20 chr1:210573594-210573614 1.0000 20 chr9:129933186-129933206 1.0000 20 chr7:148724231-148724251 1.0000 20 chr6:15952957-15952977 1.0000 20 chr6:227852-227872 1.0000 20 chr1:160616910-160616930 1.0000 20 chr8:141709564-141709584 1.0000 20 chr2:120189167-120189187 1.0000 20 chr4:56275836-56275856 1.0000 20 chr5:35302877-35302897 1.0000 20 chr19:2545103-2545123 1.0000 20 chrX:148280958-148280978 1.0000 20 chr11:68138111-68138131 1.0000 20 chr15:78177531-78177551 1.0000 20 chr1:191527671-191527691 1.0000 20 chr14:22953352-22953372 1.0000 20 chr17:30646698-30646718 1.0000 20 chr10:92961356-92961376 1.0000 20 chr22:42327990-42328010 1.0000 20 chr5:89635007-89635027 1.0000 20 chr8:6604145-6604165 1.0000 20 chrX:10030501-10030521 1.0000 20 chr10:97551557-97551577 1.0000 20 chr10:133575726-13357574 1.0000 20 chr4:104012986-104013006 1.0000 20 chr13:100018528-10001854 1.0000 20 chr13:21102744-21102764 1.0000 20 chr19:45274075-45274095 1.0000 20 chr17:38758021-38758041 1.0000 20 chr2:68638663-68638683 1.0000 20 chr9:92079544-92079564 1.0000 20 chr12:57856629-57856649 1.0000 20 chr7:100660961-100660981 1.0000 20 chr11:121238325-12123834 1.0000 20 chr21:35392897-35392917 1.0000 20 chr8:103001050-103001070 1.0000 20 chr1:207510618-207510638 1.0000 20 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/GM12878/inference_raw/MEME/RankLinear0.6_10_MEF2B/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/MEF2B.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 5000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 5000 norand= no csites= 1000 Letter frequencies in dataset: A 0.206 C 0.295 G 0.289 T 0.21 Background letter frequencies (from file dataset with add-one prior applied): A 0.206 C 0.295 G 0.289 T 0.21 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CCCYDGGG MEME-1 width = 8 sites = 98 llr = 626 E-value = 4.6e-069 ******************************************************************************** -------------------------------------------------------------------------------- Motif CCCYDGGG MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::124:2: pos.-specific C a885:::: probability G ::::2a89 matrix T :2134::1 bits 2.3 2.1 1.8 * * 1.6 * * * Relative 1.4 * * * Entropy 1.1 * * *** (9.2 bits) 0.9 *** *** 0.7 *** *** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CCCCAGGG consensus TT A sequence AG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCYDGGG MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:56275836-56275856 7 7.60e-05 agatgt cccctggg agacaa chr3:126935337-126935357 8 7.60e-05 GGGACAT CCCCAGGG AGGAG chr8:70730602-70730622 2 7.60e-05 t cccctggg agcatattag chr20:61585327-61585347 3 7.60e-05 CT CCCCAGGG ATTCAGGGCC chr5:111922528-111922548 6 7.60e-05 ccaat cccctggg acagagc chr7:31932080-31932100 8 7.60e-05 CAGTGAT CCCCTGGG ACTCT chr5:58187303-58187323 2 7.60e-05 G CCCCAGGG GAGAGCTCTG chr17:40706987-40707007 8 7.60e-05 TCTTTGT CCCCTGGG TCTGT chr9:121292097-121292117 3 7.60e-05 CT CCCCTGGG ATTGCTCTTT chr1:3487471-3487491 10 7.60e-05 TCCACCAAT CCCCAGGG ACA chr1:202134010-202134030 6 7.60e-05 GGGAA CCCCAGGG GTTCTCT chr1:32803121-32803141 8 7.60e-05 GGAGACA CCCCAGGG CCTGA chr16:15850173-15850193 2 7.60e-05 T CCCCTGGG CCCTGTGGCT chr3:69373746-69373766 6 7.60e-05 aatgt cccctggg acgcaaa chr20:44589050-44589070 12 7.60e-05 CTGCTCCCGT CCCCAGGG G chr3:149732693-149732713 13 7.60e-05 GCCCTGTGGC CCCCAGGG chr14:24835950-24835970 3 7.60e-05 GT CCCCTGGG CGGGCCCGAG chr12:131540568-13154058 3 7.60e-05 CA CCCCTGGG AGCTCCTGAT chr1:233088822-233088842 7 7.60e-05 aggatt ccccaggg ggttga chr12:10875291-10875311 9 7.60e-05 CCCGGAGA CCCCTGGG GACC chr10:110359251-11035927 1 1.30e-04 . cccttggg agatcaatcc chr15:99496294-99496314 8 1.30e-04 CCCTGAG CCCTTGGG AGTTG chr5:35302877-35302897 8 1.83e-04 AATCAAG CCCAAGGG GAAAC chr8:141709564-141709584 10 1.83e-04 CTCTCTGTC CCCAAGGG ACT chr9:129933186-129933206 12 1.83e-04 AGGTCCTGGC CCCAAGGG G chr4:116436030-116436050 10 1.83e-04 aaatactgc cccatggg taa chr16:90074390-90074410 11 1.83e-04 CCCAGGACGT CCCAAGGG GC chr21:42741474-42741494 6 1.83e-04 TCTGT CCCAAGGG AGGAAAG chr7:100660961-100660981 10 2.37e-04 TGCCCCCAC CCCCTGAG GCT chr9:92079544-92079564 11 2.37e-04 CCACTGGTCT CCCCAGAG TG chr22:42327990-42328010 9 2.37e-04 CCCACGGT CCCCAGAG GGAG chr10:92961356-92961376 3 2.37e-04 ag cccctgag ggaattctga chr17:43539559-43539579 12 2.37e-04 AGAACTAGGT CCCCAGAG A chr4:159973676-159973696 11 2.37e-04 GAACTTGATT CCCCTGAG GC chr10:133575726-13357574 4 2.90e-04 GCC CCCCGGGG AACTGTGGA chr11:61735806-61735826 11 2.90e-04 GGGACCGCCT CCCCGGGG AG chr17:72279072-72279092 2 2.90e-04 C CCCCGGGG ATGAGAAGGA chr2:6913404-6913424 10 2.90e-04 TGGCCGGGT CCCCGGGG ACG chr13:21102744-21102764 8 3.44e-04 gagggaa ctccaggg acctg chr19:11692857-11692877 6 3.44e-04 ttggc ctcctggg gattgag chr11:13338204-13338224 6 3.44e-04 CAGGC CTCCAGGG CTCTCTA chr7:95083971-95083991 13 3.83e-04 gtctttaact cccttgag chr10:1020241-1020261 3 3.83e-04 TC CCCTTGAG GAGTGTTCCC chr8:6604145-6604165 6 4.21e-04 CCCTG CCCTGGGG ACTAAAG chrX:153189651-153189671 2 4.21e-04 T CCCTGGGG ACTTATGACA chr17:61996815-61996835 5 4.21e-04 AGGT CCCTGGGG ACGAAGAA chr2:62369377-62369397 7 4.21e-04 CTCCCT CCCTGGGG AGTTGA chr4:110624828-110624848 6 4.21e-04 CCGTG CCCTGGGG ACATGCC chr13:61821964-61821984 5 4.21e-04 gatt ccctgggg gctcttac chr5:148799584-148799604 3 4.21e-04 CT CCCTGGGG AGGAAGTGGG chr7:116871042-116871062 13 4.58e-04 TCCTGCTGGC CCCAAGAG chr1:198571211-198571231 13 4.58e-04 tcaatcatct cccaagag chr17:70509286-70509306 7 4.58e-04 CTTGGC CCCAAGAG ACTCTG chr21:35392897-35392917 9 5.34e-04 TTTTGTCT CTCTTGGG GCAG chr19:2089563-2089583 1 5.34e-04 . CTCTTGGG TTAGGGGATT chr12:29879078-29879098 1 5.34e-04 . CCCAGGGG ACACCACCCT chr12:16084719-16084739 7 5.34e-04 cttgct ctcttggg aataga chr15:54375913-54375933 12 5.34e-04 agggttagat ctctaggg a chr9:88861862-88861882 8 5.34e-04 GCAGGCT CCCAGGGG ACTGT chr6:160296564-160296584 11 5.34e-04 tagatgagtt ctcttggg aa chr19:18768645-18768665 2 6.26e-04 G CCTCAGGG GCCTCTGAGC chr5:150005810-150005830 9 6.26e-04 ATGAGATC CCTCAGGG GAGT chr16:25051988-25052008 2 6.26e-04 a cctctggg gaaaaccagc chr21:37885916-37885936 3 6.26e-04 GT CCTCAGGG ACATGCCCTC chr2:96822932-96822952 4 6.26e-04 AGC CCTCAGGG ACTTGCTGT chr13:78775722-78775742 6 6.26e-04 GACTC CCTCTGGG ACTTTCT chr14:60687066-60687086 10 6.64e-04 GAGACAAGG CTCATGGG ATT chr13:32470804-32470824 7 6.64e-04 AGTAGC CTCATGGG ACTCCT chr17:30646698-30646718 10 8.05e-04 AATGAAGGT CCCTGGAG GTT chr19:18281866-18281886 3 8.97e-04 GT CCCAGGAG ACGCTGAGCA chr1:170040760-170040780 1 8.97e-04 . ctctagag ggaactaatc chr6:149081056-149081076 1 8.97e-04 . CTCTTGAG AATCACTGAA chr1:210573594-210573614 2 9.62e-04 A CTCTGGGG GTTAATGTGG chr1:45772069-45772089 10 9.62e-04 catgggagt ctctgggg ggg chr2:204553664-204553684 8 9.62e-04 GCGGTAG CCTCAGAG TCCTC chr1:8703815-8703835 10 9.62e-04 CGTGTGCCT CTCTGGGG AGG chr4:5707588-5707608 3 1.08e-03 aa ccactgGG GAATAAAATG chr2:30440560-30440580 6 1.08e-03 AAGGC CCACAGGG AATAAAA chr16:57015419-57015439 6 1.08e-03 CAAAT CTCAAGAG AGTGCCC chr15:23188103-23188123 12 1.08e-03 gtgcataagt ctcatgag a chr10:71867314-71867334 11 1.08e-03 CTGGGGAGTC CCACAGGG AC chr3:184135809-184135829 2 1.16e-03 C CACCAGGG GGAGGCGCTC chr5:131836969-131836989 5 1.28e-03 CCAC CCCCAGGT GCTCCCCA chr22:42345696-42345716 3 1.28e-03 TG CTTCAGGG AGTTACCACT chr1:1373642-1373662 13 1.28e-03 CCCCTAGTGG CCCCAGGT chr1:44784098-44784118 2 1.28e-03 C CCCCTGGT GGTATAGGTA chr12:739358-739378 5 1.31e-03 CCTG CCTTTGAG GCAAATTT chr1:24330101-24330121 8 1.31e-03 CTGAACT CCTTTGAG GTTTG chr1:17421291-17421311 1 1.37e-03 . CCTTGGGG GAGGTTGGAA chr5:76886257-76886277 12 1.69e-03 ACACAGATGG CACATGGG G chr6:227852-227872 3 1.85e-03 gt cccaaggt atttcggcca chr9:131406137-131406157 3 1.85e-03 AC CCACGGGG AGGCACCAAG chr1:191527671-191527691 10 1.95e-03 tgactgact cccctgat act chr11:121238325-12123834 9 2.31e-03 GCCTTTTG CCAATGAG AAGG chr4:113438242-113438262 3 2.31e-03 GA CACTGGGG ATTCAAACAG chr13:31018183-31018203 2 2.59e-03 T CCCCCGGG ACCCTGCCTG chr3:48236092-48236112 2 2.75e-03 C CACCGGAG GGCACTATAT chr6:149803399-149803419 1 3.44e-03 . CTTAGGAG CCCACTCGGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCYDGGG MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:56275836-56275856 7.6e-05 6_[+1]_6 chr3:126935337-126935357 7.6e-05 7_[+1]_5 chr8:70730602-70730622 7.6e-05 1_[+1]_11 chr20:61585327-61585347 7.6e-05 2_[+1]_10 chr5:111922528-111922548 7.6e-05 5_[+1]_7 chr7:31932080-31932100 7.6e-05 7_[+1]_5 chr5:58187303-58187323 7.6e-05 1_[+1]_11 chr17:40706987-40707007 7.6e-05 7_[+1]_5 chr9:121292097-121292117 7.6e-05 2_[+1]_10 chr1:3487471-3487491 7.6e-05 9_[+1]_3 chr1:202134010-202134030 7.6e-05 5_[+1]_7 chr1:32803121-32803141 7.6e-05 7_[+1]_5 chr16:15850173-15850193 7.6e-05 1_[+1]_11 chr3:69373746-69373766 7.6e-05 5_[+1]_7 chr20:44589050-44589070 7.6e-05 11_[+1]_1 chr3:149732693-149732713 7.6e-05 12_[+1] chr14:24835950-24835970 7.6e-05 2_[+1]_10 chr12:131540568-13154058 7.6e-05 2_[+1]_10 chr1:233088822-233088842 7.6e-05 6_[+1]_6 chr12:10875291-10875311 7.6e-05 8_[+1]_4 chr10:110359251-11035927 0.00013 [+1]_12 chr15:99496294-99496314 0.00013 7_[+1]_5 chr5:35302877-35302897 0.00018 7_[+1]_5 chr8:141709564-141709584 0.00018 9_[+1]_3 chr9:129933186-129933206 0.00018 11_[+1]_1 chr4:116436030-116436050 0.00018 9_[+1]_3 chr16:90074390-90074410 0.00018 10_[+1]_2 chr21:42741474-42741494 0.00018 5_[+1]_7 chr7:100660961-100660981 0.00024 9_[+1]_3 chr9:92079544-92079564 0.00024 10_[+1]_2 chr22:42327990-42328010 0.00024 8_[+1]_4 chr10:92961356-92961376 0.00024 2_[+1]_10 chr17:43539559-43539579 0.00024 11_[+1]_1 chr4:159973676-159973696 0.00024 10_[+1]_2 chr10:133575726-13357574 0.00029 3_[+1]_9 chr11:61735806-61735826 0.00029 10_[+1]_2 chr17:72279072-72279092 0.00029 1_[+1]_11 chr2:6913404-6913424 0.00029 9_[+1]_3 chr13:21102744-21102764 0.00034 7_[+1]_5 chr19:11692857-11692877 0.00034 5_[+1]_7 chr11:13338204-13338224 0.00034 5_[+1]_7 chr7:95083971-95083991 0.00038 12_[+1] chr10:1020241-1020261 0.00038 2_[+1]_10 chr8:6604145-6604165 0.00042 5_[+1]_7 chrX:153189651-153189671 0.00042 1_[+1]_11 chr17:61996815-61996835 0.00042 4_[+1]_8 chr2:62369377-62369397 0.00042 6_[+1]_6 chr4:110624828-110624848 0.00042 5_[+1]_7 chr13:61821964-61821984 0.00042 4_[+1]_8 chr5:148799584-148799604 0.00042 2_[+1]_10 chr7:116871042-116871062 0.00046 12_[+1] chr1:198571211-198571231 0.00046 12_[+1] chr17:70509286-70509306 0.00046 6_[+1]_6 chr21:35392897-35392917 0.00053 8_[+1]_4 chr19:2089563-2089583 0.00053 [+1]_12 chr12:29879078-29879098 0.00053 [+1]_12 chr12:16084719-16084739 0.00053 6_[+1]_6 chr15:54375913-54375933 0.00053 11_[+1]_1 chr9:88861862-88861882 0.00053 7_[+1]_5 chr6:160296564-160296584 0.00053 10_[+1]_2 chr19:18768645-18768665 0.00063 1_[+1]_11 chr5:150005810-150005830 0.00063 8_[+1]_4 chr16:25051988-25052008 0.00063 1_[+1]_11 chr21:37885916-37885936 0.00063 2_[+1]_10 chr2:96822932-96822952 0.00063 3_[+1]_9 chr13:78775722-78775742 0.00063 5_[+1]_7 chr14:60687066-60687086 0.00066 9_[+1]_3 chr13:32470804-32470824 0.00066 6_[+1]_6 chr17:30646698-30646718 0.00081 9_[+1]_3 chr19:18281866-18281886 0.0009 2_[+1]_10 chr1:170040760-170040780 0.0009 [+1]_12 chr6:149081056-149081076 0.0009 [+1]_12 chr1:210573594-210573614 0.00096 1_[+1]_11 chr1:45772069-45772089 0.00096 9_[+1]_3 chr2:204553664-204553684 0.00096 7_[+1]_5 chr1:8703815-8703835 0.00096 9_[+1]_3 chr4:5707588-5707608 0.0011 2_[+1]_10 chr2:30440560-30440580 0.0011 5_[+1]_7 chr16:57015419-57015439 0.0011 5_[+1]_7 chr15:23188103-23188123 0.0011 11_[+1]_1 chr10:71867314-71867334 0.0011 10_[+1]_2 chr3:184135809-184135829 0.0012 1_[+1]_11 chr5:131836969-131836989 0.0013 4_[+1]_8 chr22:42345696-42345716 0.0013 2_[+1]_10 chr1:1373642-1373662 0.0013 12_[+1] chr1:44784098-44784118 0.0013 1_[+1]_11 chr12:739358-739378 0.0013 4_[+1]_8 chr1:24330101-24330121 0.0013 7_[+1]_5 chr1:17421291-17421311 0.0014 [+1]_12 chr5:76886257-76886277 0.0017 11_[+1]_1 chr6:227852-227872 0.0018 2_[+1]_10 chr9:131406137-131406157 0.0018 2_[+1]_10 chr1:191527671-191527691 0.002 9_[+1]_3 chr11:121238325-12123834 0.0023 8_[+1]_4 chr4:113438242-113438262 0.0023 2_[+1]_10 chr13:31018183-31018203 0.0026 1_[+1]_11 chr3:48236092-48236112 0.0028 1_[+1]_11 chr6:149803399-149803419 0.0034 [+1]_12 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCYDGGG MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CCCYDGGG width=8 seqs=98 chr4:56275836-56275856 ( 7) CCCCTGGG 1 chr3:126935337-126935357 ( 8) CCCCAGGG 1 chr8:70730602-70730622 ( 2) CCCCTGGG 1 chr20:61585327-61585347 ( 3) CCCCAGGG 1 chr5:111922528-111922548 ( 6) CCCCTGGG 1 chr7:31932080-31932100 ( 8) CCCCTGGG 1 chr5:58187303-58187323 ( 2) CCCCAGGG 1 chr17:40706987-40707007 ( 8) CCCCTGGG 1 chr9:121292097-121292117 ( 3) CCCCTGGG 1 chr1:3487471-3487491 ( 10) CCCCAGGG 1 chr1:202134010-202134030 ( 6) CCCCAGGG 1 chr1:32803121-32803141 ( 8) CCCCAGGG 1 chr16:15850173-15850193 ( 2) CCCCTGGG 1 chr3:69373746-69373766 ( 6) CCCCTGGG 1 chr20:44589050-44589070 ( 12) CCCCAGGG 1 chr3:149732693-149732713 ( 13) CCCCAGGG 1 chr14:24835950-24835970 ( 3) CCCCTGGG 1 chr12:131540568-13154058 ( 3) CCCCTGGG 1 chr1:233088822-233088842 ( 7) CCCCAGGG 1 chr12:10875291-10875311 ( 9) CCCCTGGG 1 chr10:110359251-11035927 ( 1) CCCTTGGG 1 chr15:99496294-99496314 ( 8) CCCTTGGG 1 chr5:35302877-35302897 ( 8) CCCAAGGG 1 chr8:141709564-141709584 ( 10) CCCAAGGG 1 chr9:129933186-129933206 ( 12) CCCAAGGG 1 chr4:116436030-116436050 ( 10) CCCATGGG 1 chr16:90074390-90074410 ( 11) CCCAAGGG 1 chr21:42741474-42741494 ( 6) CCCAAGGG 1 chr7:100660961-100660981 ( 10) CCCCTGAG 1 chr9:92079544-92079564 ( 11) CCCCAGAG 1 chr22:42327990-42328010 ( 9) CCCCAGAG 1 chr10:92961356-92961376 ( 3) CCCCTGAG 1 chr17:43539559-43539579 ( 12) CCCCAGAG 1 chr4:159973676-159973696 ( 11) CCCCTGAG 1 chr10:133575726-13357574 ( 4) CCCCGGGG 1 chr11:61735806-61735826 ( 11) CCCCGGGG 1 chr17:72279072-72279092 ( 2) CCCCGGGG 1 chr2:6913404-6913424 ( 10) CCCCGGGG 1 chr13:21102744-21102764 ( 8) CTCCAGGG 1 chr19:11692857-11692877 ( 6) CTCCTGGG 1 chr11:13338204-13338224 ( 6) CTCCAGGG 1 chr7:95083971-95083991 ( 13) CCCTTGAG 1 chr10:1020241-1020261 ( 3) CCCTTGAG 1 chr8:6604145-6604165 ( 6) CCCTGGGG 1 chrX:153189651-153189671 ( 2) CCCTGGGG 1 chr17:61996815-61996835 ( 5) CCCTGGGG 1 chr2:62369377-62369397 ( 7) CCCTGGGG 1 chr4:110624828-110624848 ( 6) CCCTGGGG 1 chr13:61821964-61821984 ( 5) CCCTGGGG 1 chr5:148799584-148799604 ( 3) CCCTGGGG 1 chr7:116871042-116871062 ( 13) CCCAAGAG 1 chr1:198571211-198571231 ( 13) CCCAAGAG 1 chr17:70509286-70509306 ( 7) CCCAAGAG 1 chr21:35392897-35392917 ( 9) CTCTTGGG 1 chr19:2089563-2089583 ( 1) CTCTTGGG 1 chr12:29879078-29879098 ( 1) CCCAGGGG 1 chr12:16084719-16084739 ( 7) CTCTTGGG 1 chr15:54375913-54375933 ( 12) CTCTAGGG 1 chr9:88861862-88861882 ( 8) CCCAGGGG 1 chr6:160296564-160296584 ( 11) CTCTTGGG 1 chr19:18768645-18768665 ( 2) CCTCAGGG 1 chr5:150005810-150005830 ( 9) CCTCAGGG 1 chr16:25051988-25052008 ( 2) CCTCTGGG 1 chr21:37885916-37885936 ( 3) CCTCAGGG 1 chr2:96822932-96822952 ( 4) CCTCAGGG 1 chr13:78775722-78775742 ( 6) CCTCTGGG 1 chr14:60687066-60687086 ( 10) CTCATGGG 1 chr13:32470804-32470824 ( 7) CTCATGGG 1 chr17:30646698-30646718 ( 10) CCCTGGAG 1 chr19:18281866-18281886 ( 3) CCCAGGAG 1 chr1:170040760-170040780 ( 1) CTCTAGAG 1 chr6:149081056-149081076 ( 1) CTCTTGAG 1 chr1:210573594-210573614 ( 2) CTCTGGGG 1 chr1:45772069-45772089 ( 10) CTCTGGGG 1 chr2:204553664-204553684 ( 8) CCTCAGAG 1 chr1:8703815-8703835 ( 10) CTCTGGGG 1 chr4:5707588-5707608 ( 3) CCACTGGG 1 chr2:30440560-30440580 ( 6) CCACAGGG 1 chr16:57015419-57015439 ( 6) CTCAAGAG 1 chr15:23188103-23188123 ( 12) CTCATGAG 1 chr10:71867314-71867334 ( 11) CCACAGGG 1 chr3:184135809-184135829 ( 2) CACCAGGG 1 chr5:131836969-131836989 ( 5) CCCCAGGT 1 chr22:42345696-42345716 ( 3) CTTCAGGG 1 chr1:1373642-1373662 ( 13) CCCCAGGT 1 chr1:44784098-44784118 ( 2) CCCCTGGT 1 chr12:739358-739378 ( 5) CCTTTGAG 1 chr1:24330101-24330121 ( 8) CCTTTGAG 1 chr1:17421291-17421311 ( 1) CCTTGGGG 1 chr5:76886257-76886277 ( 12) CACATGGG 1 chr6:227852-227872 ( 3) CCCAAGGT 1 chr9:131406137-131406157 ( 3) CCACGGGG 1 chr1:191527671-191527691 ( 10) CCCCTGAT 1 chr11:121238325-12123834 ( 9) CCAATGAG 1 chr4:113438242-113438262 ( 3) CACTGGGG 1 chr13:31018183-31018203 ( 2) CCCCCGGG 1 chr3:48236092-48236112 ( 2) CACCGGAG 1 chr6:149803399-149803419 ( 1) CTTAGGAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCYDGGG MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 5.48877 E= 4.6e-069 -1326 176 -1326 -1326 -233 137 -1326 -12 -201 149 -1326 -78 -1 85 -1326 33 88 -485 -30 84 -1326 -1326 179 -1326 25 -1326 139 -1326 -1326 -1326 172 -204 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCYDGGG MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 98 E= 4.6e-069 0.000000 1.000000 0.000000 0.000000 0.040816 0.765306 0.000000 0.193878 0.051020 0.826531 0.000000 0.122449 0.204082 0.530612 0.000000 0.265306 0.377551 0.010204 0.234694 0.377551 0.000000 0.000000 1.000000 0.000000 0.244898 0.000000 0.755102 0.000000 0.000000 0.000000 0.948980 0.051020 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CCCYDGGG MEME-1 regular expression -------------------------------------------------------------------------------- CCC[CTA][ATG]G[GA]G -------------------------------------------------------------------------------- Time 2.62 secs. ******************************************************************************** ******************************************************************************** MOTIF AAGARACW MEME-2 width = 8 sites = 3 llr = 32 E-value = 7.0e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAGARACW MEME-2 Description -------------------------------------------------------------------------------- Simplified A aa:a7a:7 pos.-specific C ::::::a: probability G ::a:3::: matrix T :::::::3 bits 2.3 ** * * 2.1 ** * * 1.8 **** ** 1.6 **** ** Relative 1.4 **** *** Entropy 1.1 ******** (15.2 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel AAGAAACA consensus G T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGARACW MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:83380077-83380097 9 6.52e-06 GTGGGTGG AAGAAACA GCTC chr1:28503862-28503882 7 6.52e-06 GAGACC AAGAAACA TTGAGC chr9:19129975-19129995 2 3.16e-05 C AAGAGACT CTTCAAGCCC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGARACW MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:83380077-83380097 6.5e-06 8_[+2]_4 chr1:28503862-28503882 6.5e-06 6_[+2]_6 chr9:19129975-19129995 3.2e-05 1_[+2]_11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGARACW MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAGARACW width=8 seqs=3 chr4:83380077-83380097 ( 9) AAGAAACA 1 chr1:28503862-28503882 ( 7) AAGAAACA 1 chr9:19129975-19129995 ( 2) AAGAGACT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGARACW MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 10.5277 E= 7.0e+003 228 -823 -823 -823 228 -823 -823 -823 -823 -823 179 -823 228 -823 -823 -823 169 -823 21 -823 228 -823 -823 -823 -823 176 -823 -823 169 -823 -823 66 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGARACW MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 3 E= 7.0e+003 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.666667 0.000000 0.333333 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.666667 0.000000 0.000000 0.333333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAGARACW MEME-2 regular expression -------------------------------------------------------------------------------- AAGA[AG]AC[AT] -------------------------------------------------------------------------------- Time 3.48 secs. ******************************************************************************** ******************************************************************************** MOTIF TTATMAAA MEME-3 width = 8 sites = 2 llr = 23 E-value = 3.4e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTATMAAA MEME-3 Description -------------------------------------------------------------------------------- Simplified A ::a:5aaa pos.-specific C ::::5::: probability G :::::::: matrix T aa:a:::: bits 2.3 **** *** 2.1 **** *** 1.8 **** *** 1.6 **** *** Relative 1.4 **** *** Entropy 1.1 **** *** (16.9 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTATAAAA consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTATMAAA MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr8:22740551-22740571 13 3.44e-06 ggatctgtga ttataaaa chr14:22953352-22953372 10 8.36e-06 ACTGAGGTC TTATCAAA TTA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTATMAAA MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr8:22740551-22740571 3.4e-06 12_[+3] chr14:22953352-22953372 8.4e-06 9_[+3]_3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTATMAAA MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTATMAAA width=8 seqs=2 chr8:22740551-22740571 ( 13) TTATAAAA 1 chr14:22953352-22953372 ( 10) TTATCAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTATMAAA MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 10.6653 E= 3.4e+003 -765 -765 -765 224 -765 -765 -765 224 228 -765 -765 -765 -765 -765 -765 224 128 76 -765 -765 228 -765 -765 -765 228 -765 -765 -765 228 -765 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTATMAAA MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 3.4e+003 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.500000 0.500000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTATMAAA MEME-3 regular expression -------------------------------------------------------------------------------- TTAT[AC]AAA -------------------------------------------------------------------------------- Time 4.18 secs. ******************************************************************************** ******************************************************************************** MOTIF CAATAWAT MEME-4 width = 8 sites = 2 llr = 23 E-value = 4.5e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif CAATAWAT MEME-4 Description -------------------------------------------------------------------------------- Simplified A :aa:a5a: pos.-specific C a::::::: probability G :::::::: matrix T :::a:5:a bits 2.3 **** ** 2.1 **** ** 1.8 ***** ** 1.6 ***** ** Relative 1.4 ******** Entropy 1.1 ******** (16.7 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CAATAAAT consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAATAWAT MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:38758021-38758041 3 9.75e-06 gg caataaat caaagtcacc chr11:60589871-60589891 2 9.75e-06 C CAATATAT GCAGCCGAGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAATAWAT MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:38758021-38758041 9.7e-06 2_[+4]_10 chr11:60589871-60589891 9.7e-06 1_[+4]_11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAATAWAT MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CAATAWAT width=8 seqs=2 chr17:38758021-38758041 ( 3) CAATAAAT 1 chr11:60589871-60589891 ( 2) CAATATAT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAATAWAT MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 10.6653 E= 4.5e+003 -765 176 -765 -765 228 -765 -765 -765 228 -765 -765 -765 -765 -765 -765 224 228 -765 -765 -765 128 -765 -765 124 228 -765 -765 -765 -765 -765 -765 224 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAATAWAT MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 4.5e+003 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.500000 0.000000 0.000000 0.500000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAATAWAT MEME-4 regular expression -------------------------------------------------------------------------------- CAATA[AT]AT -------------------------------------------------------------------------------- Time 4.96 secs. ******************************************************************************** ******************************************************************************** MOTIF BAGAGAAT MEME-5 width = 8 sites = 4 llr = 40 E-value = 6.6e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif BAGAGAAT MEME-5 Description -------------------------------------------------------------------------------- Simplified A :a:a:aa: pos.-specific C 3::::::: probability G 3:a:a::3 matrix T 5::::::8 bits 2.3 * * ** 2.1 * * ** 1.8 ****** 1.6 ****** Relative 1.4 ******* Entropy 1.1 ******* (14.5 bits) 0.9 ******* 0.7 ******* 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TAGAGAAT consensus C G sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAGAGAAT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr22:25966104-25966124 10 6.63e-06 AGAGACTGA TAGAGAAT TCC chr11:125243819-12524383 5 2.51e-05 CCCC GAGAGAAT GACAGCCA chr19:35892601-35892621 3 2.51e-05 cc cagagaat cgcagtcccc chr9:140013448-140013468 12 3.42e-05 ctggggagtt tagagaag a -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAGAGAAT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr22:25966104-25966124 6.6e-06 9_[+5]_3 chr11:125243819-12524383 2.5e-05 4_[+5]_8 chr19:35892601-35892621 2.5e-05 2_[+5]_10 chr9:140013448-140013468 3.4e-05 11_[+5]_1 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAGAGAAT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF BAGAGAAT width=8 seqs=4 chr22:25966104-25966124 ( 10) TAGAGAAT 1 chr11:125243819-12524383 ( 5) GAGAGAAT 1 chr19:35892601-35892621 ( 3) CAGAGAAT 1 chr9:140013448-140013468 ( 12) TAGAGAAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAGAGAAT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 9.66445 E= 6.6e+003 -865 -24 -21 125 228 -865 -865 -865 -865 -865 179 -865 228 -865 -865 -865 -865 -865 179 -865 228 -865 -865 -865 228 -865 -865 -865 -865 -865 -21 183 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAGAGAAT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 4 E= 6.6e+003 0.000000 0.250000 0.250000 0.500000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.250000 0.750000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif BAGAGAAT MEME-5 regular expression -------------------------------------------------------------------------------- [TCG]AGAGAA[TG] -------------------------------------------------------------------------------- Time 5.68 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr6:149803399-149803419 3.19e-01 20 chr1:44784098-44784118 2.07e-01 20 chr11:69485192-69485212 3.05e-01 20 chr12:10875291-10875311 5.65e-02 8_[+1(7.60e-05)]_4 chr17:9828254-9828274 1.72e-01 20 chr8:23366532-23366552 2.01e-01 20 chr3:48236092-48236112 1.28e-02 20 chr21:42741474-42741494 1.45e-02 20 chr6:160296564-160296584 8.49e-02 20 chr15:78183714-78183734 9.96e-01 20 chr16:89041258-89041278 7.94e-01 20 chr22:30787260-30787280 9.96e-01 20 chr1:233088822-233088842 6.59e-02 6_[+1(7.60e-05)]_6 chr10:88731164-88731184 1.00e+00 20 chr12:131540568-13154058 1.48e-01 2_[+1(7.60e-05)]_10 chr9:125226361-125226381 9.79e-01 20 chr12:131455345-13145536 9.50e-01 20 chr10:1020241-1020261 7.26e-02 20 chr5:148799584-148799604 1.10e-01 20 chr7:95083971-95083991 1.02e-01 20 chr14:24835950-24835970 1.78e-01 2_[+1(7.60e-05)]_10 chr6:149081056-149081076 2.65e-04 20 chrX:106953967-106953987 3.11e-01 20 chr10:71867314-71867334 2.35e-01 20 chr2:7567591-7567611 5.92e-01 20 chr6:33138081-33138101 4.96e-01 20 chr15:99496294-99496314 9.82e-02 20 chr3:149732693-149732713 1.79e-01 12_[+1(7.60e-05)] chrX:19881799-19881819 7.88e-02 20 chr1:26869777-26869797 9.99e-01 20 chr2:8143027-8143047 2.20e-03 20 chr15:23188103-23188123 1.14e-02 20 chr16:57015419-57015439 2.01e-04 20 chr20:44589050-44589070 1.77e-01 11_[+1(7.60e-05)]_1 chr13:61821964-61821984 3.21e-01 20 chr13:31018183-31018203 6.71e-01 20 chr13:78775722-78775742 1.76e-01 20 chr6:97243013-97243033 3.35e-01 20 chr6:41301602-41301622 9.92e-01 20 chr1:211870858-211870878 1.87e-01 20 chr17:71278252-71278272 6.71e-01 20 chr11:5145450-5145470 4.67e-01 20 chr4:110624828-110624848 1.82e-01 20 chr1:1107255-1107275 6.01e-01 20 chr3:69373746-69373766 9.41e-02 5_[+1(7.60e-05)]_7 chr9:88861862-88861882 8.53e-02 20 chr5:153900688-153900708 9.55e-02 20 chr2:30440560-30440580 4.05e-05 20 chr3:52058009-52058029 1.00e+00 20 chr9:140013448-140013468 1.22e-03 11_[+5(3.42e-05)]_1 chr10:52107410-52107430 9.09e-01 20 chr14:68487800-68487820 7.61e-01 20 chr19:3172752-3172772 1.00e+00 20 chr3:171515324-171515344 1.32e-02 20 chr13:99988068-99988088 2.50e-01 20 chr1:110198645-110198665 7.06e-01 20 chr2:96822932-96822952 3.01e-02 20 chr19:7410875-7410895 9.53e-01 20 chr22:25966104-25966124 8.64e-04 9_[+5(6.63e-06)]_3 chr5:7794535-7794555 8.55e-01 20 chr4:113438242-113438262 6.06e-02 20 chr5:37185013-37185033 1.88e-01 20 chr16:58137068-58137088 8.53e-01 20 chr18:12885780-12885800 2.35e-02 20 chr1:1373642-1373662 5.08e-01 20 chr20:47085194-47085214 3.90e-01 20 chr5:168307086-168307106 1.00e+00 20 chr2:62369377-62369397 1.97e-01 20 chr1:24330101-24330121 3.11e-01 20 chr18:46305212-46305232 7.98e-01 20 chr16:15850173-15850193 1.59e-01 1_[+1(7.60e-05)]_11 chr17:43117170-43117190 8.64e-02 20 chr15:54375913-54375933 1.03e-01 20 chr1:203142873-203142893 1.00e+00 20 chr14:33980358-33980378 8.63e-02 20 chr22:42345696-42345716 5.47e-02 20 chr9:5583486-5583506 6.54e-01 20 chr21:37885916-37885936 6.66e-02 20 chr19:35892601-35892621 4.64e-03 2_[+5(2.51e-05)]_10 chr17:70509286-70509306 2.72e-05 9_[+2(3.16e-05)]_3 chr9:107535167-107535187 4.04e-01 20 chr1:170040760-170040780 6.16e-03 20 chr1:28503862-28503882 4.61e-04 6_[+2(6.52e-06)]_6 chr12:110809375-11080939 1.00e+00 20 chr16:57033966-57033986 1.90e-01 20 chr4:156681278-156681298 9.87e-01 20 chr3:184135809-184135829 4.45e-01 20 chr10:110359251-11035927 1.20e-02 20 chr1:31950342-31950362 8.25e-01 20 chr2:20414134-20414154 9.12e-01 20 chr3:178764544-178764564 1.94e-01 20 chr5:131836969-131836989 5.35e-01 20 chr2:6913404-6913424 2.57e-01 20 chr4:114559588-114559608 8.61e-01 20 chr6:1575669-1575689 2.41e-01 20 chr17:61996815-61996835 1.26e-01 20 chrX:11783020-11783040 4.80e-01 20 chr16:11836963-11836983 1.07e-01 20 chr1:8703815-8703835 4.06e-01 20 chr19:42618305-42618325 9.43e-01 20 chr12:11933606-11933626 2.97e-01 20 chr14:33978082-33978102 9.10e-01 20 chr4:159973676-159973696 1.60e-01 20 chr4:75994878-75994898 7.07e-02 20 chr1:32803121-32803141 2.12e-02 7_[+1(7.60e-05)]_5 chr5:71748179-71748199 9.99e-01 20 chr12:16084719-16084739 3.92e-02 20 chr5:132143176-132143196 8.30e-01 20 chr8:70725809-70725829 2.57e-01 20 chr17:74816358-74816378 1.92e-01 20 chr16:90074390-90074410 1.21e-01 20 chr1:2508227-2508247 7.11e-01 20 chr8:101457583-101457603 2.35e-01 20 chr11:125243819-12524383 1.28e-03 4_[+5(2.51e-05)]_8 chr10:64287244-64287264 5.12e-01 20 chr17:43539559-43539579 5.86e-02 20 chr15:31631224-31631244 1.00e+00 20 chr17:62804933-62804953 3.76e-01 20 chr9:140172213-140172233 9.39e-01 20 chr4:83380077-83380097 2.76e-03 8_[+2(6.52e-06)]_4 chr4:159787108-159787128 3.52e-01 20 chr16:25051988-25052008 5.88e-02 20 chr19:10714215-10714235 1.00e+00 20 chr22:40295262-40295282 5.13e-01 20 chr16:13646695-13646715 4.65e-01 20 chr13:32470804-32470824 7.38e-02 20 chr14:100535936-10053595 2.59e-01 20 chr5:176937403-176937423 7.55e-01 20 chr12:29879078-29879098 7.39e-02 20 chr9:19129975-19129995 4.61e-04 1_[+2(3.16e-05)]_11 chr1:202134010-202134030 9.05e-02 5_[+1(7.60e-05)]_7 chr4:116436030-116436050 1.39e-01 20 chrX:153189651-153189671 3.82e-03 20 chr9:140162559-140162579 8.92e-01 20 chr11:60589871-60589891 8.37e-03 1_[+4(9.75e-06)]_11 chr1:3487471-3487491 7.72e-03 9_[+1(7.60e-05)]_3 chr9:121292097-121292117 1.02e-01 2_[+1(7.60e-05)]_10 chr17:72279072-72279092 1.63e-02 20 chr3:36933283-36933303 2.50e-01 20 chr12:739358-739378 1.11e-01 20 chr19:35975718-35975738 5.20e-01 20 chr11:69025950-69025970 8.54e-01 20 chr17:40706987-40707007 1.35e-01 7_[+1(7.60e-05)]_5 chr10:125974665-12597468 9.93e-01 20 chr8:142106737-142106757 9.33e-01 20 chr1:25848902-25848922 9.94e-01 20 chr2:204553664-204553684 2.00e-01 20 chr1:17421291-17421311 3.63e-01 20 chr18:39768112-39768132 9.14e-01 20 chr4:156588700-156588720 7.01e-01 20 chr11:46504831-46504851 1.21e-01 20 chr1:25071559-25071579 1.00e+00 20 chr8:96103648-96103668 7.77e-02 20 chr16:18980718-18980738 6.58e-01 20 chr17:62009763-62009783 7.71e-01 20 chr5:150005810-150005830 8.87e-02 20 chr4:7256621-7256641 1.00e+00 20 chr9:112891441-112891461 1.26e-03 20 chr19:18281866-18281886 4.89e-02 20 chr11:61735806-61735826 2.64e-01 20 chr9:131406137-131406157 2.93e-01 20 chr10:12306670-12306690 9.19e-01 20 chr19:18768645-18768665 3.12e-01 20 chr5:137799755-137799775 9.39e-01 20 chr1:198571211-198571231 7.34e-02 20 chr1:205283053-205283073 4.90e-01 20 chr7:116871042-116871062 3.89e-01 20 chr7:1126266-1126286 9.94e-01 20 chr11:58414830-58414850 8.88e-01 20 chr6:6546940-6546960 9.97e-01 20 chr6:89203657-89203677 2.95e-01 20 chr11:64405665-64405685 5.80e-01 20 chr17:17595435-17595455 8.85e-01 20 chr11:13338204-13338224 3.14e-01 20 chr19:11692857-11692877 1.61e-01 20 chr5:58187303-58187323 3.15e-02 1_[+1(7.60e-05)]_11 chr7:31932080-31932100 5.01e-02 7_[+1(7.60e-05)]_5 chr10:82349821-82349841 7.43e-01 20 chr5:76886257-76886277 5.58e-02 20 chr1:27425645-27425665 9.96e-01 20 chr6:76445832-76445852 2.37e-03 20 chr6:15254458-15254478 1.59e-01 20 chr17:74478108-74478128 4.07e-01 20 chr7:148272840-148272860 6.36e-01 20 chr4:113211630-113211650 6.78e-02 20 chr5:111922528-111922548 3.16e-02 5_[+1(7.60e-05)]_7 chr1:840838-840858 1.00e+00 20 chr16:11043480-11043500 2.15e-01 20 chr4:38762695-38762715 9.58e-01 20 chr7:120496947-120496967 1.00e+00 20 chr20:61585327-61585347 1.46e-02 2_[+1(7.60e-05)]_10 chr13:40634646-40634666 5.97e-01 20 chr10:1496792-1496812 8.87e-01 20 chr8:70730602-70730622 1.40e-03 1_[+1(7.60e-05)]_11 chr2:153422878-153422898 8.27e-01 20 chr20:10340553-10340573 5.69e-01 20 chr8:135612652-135612672 8.86e-01 20 chr1:45772069-45772089 2.26e-01 20 chr6:12354924-12354944 9.89e-01 20 chrX:78515072-78515092 9.99e-01 20 chr19:2089563-2089583 2.64e-02 20 chr10:25218280-25218300 9.97e-01 20 chr8:22740551-22740571 1.97e-03 12_[+3(3.44e-06)] chr14:60687066-60687086 5.04e-03 20 chr11:67808218-67808238 7.09e-01 20 chr20:61641120-61641140 1.00e+00 20 chr1:1603360-1603380 1.26e-01 20 chr3:126935337-126935357 4.88e-02 7_[+1(7.60e-05)]_5 chr1:109655474-109655494 9.09e-01 20 chr2:242755107-242755127 5.05e-01 20 chr16:28942221-28942241 1.77e-01 20 chr7:151451342-151451362 7.56e-01 20 chr4:5707588-5707608 2.99e-05 20 chr1:210573594-210573614 3.01e-01 20 chr9:129933186-129933206 2.41e-01 20 chr7:148724231-148724251 3.75e-01 20 chr6:15952957-15952977 5.05e-01 20 chr6:227852-227872 3.86e-02 20 chr1:160616910-160616930 9.98e-01 20 chr8:141709564-141709584 2.59e-03 20 chr2:120189167-120189187 2.09e-01 20 chr4:56275836-56275856 1.46e-02 6_[+1(7.60e-05)]_6 chr5:35302877-35302897 1.24e-01 20 chr19:2545103-2545123 9.54e-01 20 chrX:148280958-148280978 5.32e-01 20 chr11:68138111-68138131 8.63e-01 20 chr15:78177531-78177551 8.77e-01 20 chr1:191527671-191527691 2.33e-01 20 chr14:22953352-22953372 1.46e-03 9_[+3(8.36e-06)]_3 chr17:30646698-30646718 1.58e-01 20 chr10:92961356-92961376 3.40e-03 20 chr22:42327990-42328010 1.01e-01 20 chr5:89635007-89635027 6.57e-02 20 chr8:6604145-6604165 2.54e-02 20 chrX:10030501-10030521 2.25e-02 20 chr10:97551557-97551577 1.31e-02 20 chr10:133575726-13357574 1.37e-01 20 chr4:104012986-104013006 1.77e-01 20 chr13:100018528-10001854 6.55e-01 20 chr13:21102744-21102764 1.57e-02 20 chr19:45274075-45274095 8.75e-01 20 chr17:38758021-38758041 3.31e-04 2_[+4(9.75e-06)]_10 chr2:68638663-68638683 5.14e-01 20 chr9:92079544-92079564 1.61e-01 20 chr12:57856629-57856649 2.51e-02 20 chr7:100660961-100660981 1.37e-01 20 chr11:121238325-12123834 2.58e-02 20 chr21:35392897-35392917 2.73e-01 20 chr8:103001050-103001070 1.40e-01 20 chr1:207510618-207510638 3.53e-02 20 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n05.farnam.hpc.yale.internal ********************************************************************************