******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/IRF4.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr4:89449088-89449108 1.0000 20 chr6:150739448-150739468 1.0000 20 chr11:133847074-13384709 1.0000 20 chr4:146950469-146950489 1.0000 20 chr3:122252861-122252881 1.0000 20 chr20:53250594-53250614 1.0000 20 chr18:10838794-10838814 1.0000 20 chr8:134165329-134165349 1.0000 20 chr2:216910019-216910039 1.0000 20 chr2:218945981-218946001 1.0000 20 chr14:68147032-68147052 1.0000 20 chr6:14666316-14666336 1.0000 20 chr8:26105966-26105986 1.0000 20 chr18:72519233-72519253 1.0000 20 chr6:116038404-116038424 1.0000 20 chr2:47137052-47137072 1.0000 20 chr2:175257617-175257637 1.0000 20 chr11:115456277-11545629 1.0000 20 chr7:133977991-133978011 1.0000 20 chr4:187055600-187055620 1.0000 20 chr18:13375448-13375468 1.0000 20 chr21:43925386-43925406 1.0000 20 chr3:155213395-155213415 1.0000 20 chr1:167632349-167632369 1.0000 20 chr17:48360777-48360797 1.0000 20 chr20:9596965-9596985 1.0000 20 chr2:10054965-10054985 1.0000 20 chr15:57833102-57833122 1.0000 20 chr17:68133683-68133703 1.0000 20 chr7:139912463-139912483 1.0000 20 chr19:1904482-1904502 1.0000 20 chr18:72885171-72885191 1.0000 20 chr1:65631468-65631488 1.0000 20 chr11:102239381-10223940 1.0000 20 chr11:108094770-10809479 1.0000 20 chr2:12641767-12641787 1.0000 20 chr18:34218378-34218398 1.0000 20 chr10:101934671-10193469 1.0000 20 chr2:75539308-75539328 1.0000 20 chr22:40446415-40446435 1.0000 20 chr21:38531504-38531524 1.0000 20 chr10:6178422-6178442 1.0000 20 chr11:100796829-10079684 1.0000 20 chr2:207802450-207802470 1.0000 20 chr10:329942-329962 1.0000 20 chr15:57079346-57079366 1.0000 20 chr3:17088894-17088914 1.0000 20 chr17:62151887-62151907 1.0000 20 chr1:63087857-63087877 1.0000 20 chr3:112770246-112770266 1.0000 20 chr6:73450042-73450062 1.0000 20 chr17:78232785-78232805 1.0000 20 chr5:167676236-167676256 1.0000 20 chr21:36423041-36423061 1.0000 20 chr3:3130847-3130867 1.0000 20 chr15:101679306-10167932 1.0000 20 chr2:18093572-18093592 1.0000 20 chr2:8256990-8257010 1.0000 20 chr11:4721121-4721141 1.0000 20 chr2:98583565-98583585 1.0000 20 chr15:79965939-79965959 1.0000 20 chr19:36202382-36202402 1.0000 20 chr8:8310325-8310345 1.0000 20 chr3:47267305-47267325 1.0000 20 chr1:209925489-209925509 1.0000 20 chr8:37595312-37595332 1.0000 20 chr10:32438249-32438269 1.0000 20 chr5:55273991-55274011 1.0000 20 chr9:109935368-109935388 1.0000 20 chr8:39706382-39706402 1.0000 20 chr20:43213885-43213905 1.0000 20 chr5:116032272-116032292 1.0000 20 chr2:204736403-204736423 1.0000 20 chr7:7291561-7291581 1.0000 20 chr17:8842933-8842953 1.0000 20 chr5:179293877-179293897 1.0000 20 chr15:50682887-50682907 1.0000 20 chr19:19521767-19521787 1.0000 20 chr5:123860424-123860444 1.0000 20 chr1:159091942-159091962 1.0000 20 chr3:127481556-127481576 1.0000 20 chr17:56582557-56582577 1.0000 20 chr20:30866339-30866359 1.0000 20 chr8:74748081-74748101 1.0000 20 chr11:128627958-12862797 1.0000 20 chr11:66659808-66659828 1.0000 20 chr5:172117437-172117457 1.0000 20 chr4:24858322-24858342 1.0000 20 chr17:48468970-48468990 1.0000 20 chr12:132258277-13225829 1.0000 20 chr5:99501210-99501230 1.0000 20 chr11:120580712-12058073 1.0000 20 chr15:59691831-59691851 1.0000 20 chr4:113249238-113249258 1.0000 20 chr4:6425515-6425535 1.0000 20 chr18:74775368-74775388 1.0000 20 chr18:42289921-42289941 1.0000 20 chr1:236323950-236323970 1.0000 20 chr7:20257120-20257140 1.0000 20 chr12:92172815-92172835 1.0000 20 chr2:20565322-20565342 1.0000 20 chr1:200849611-200849631 1.0000 20 chr9:6185240-6185260 1.0000 20 chr5:123919624-123919644 1.0000 20 chr3:108012883-108012903 1.0000 20 chr12:105324617-10532463 1.0000 20 chr1:28624516-28624536 1.0000 20 chr2:38374196-38374216 1.0000 20 chr6:106611980-106612000 1.0000 20 chr7:37758880-37758900 1.0000 20 chr19:10987521-10987541 1.0000 20 chr10:27026869-27026889 1.0000 20 chr10:11117008-11117028 1.0000 20 chr2:152697073-152697093 1.0000 20 chr3:197588284-197588304 1.0000 20 chr13:53495525-53495545 1.0000 20 chr10:73734406-73734426 1.0000 20 chr9:5510502-5510522 1.0000 20 chr3:38548787-38548807 1.0000 20 chr20:3400975-3400995 1.0000 20 chr12:96896524-96896544 1.0000 20 chr9:102574115-102574135 1.0000 20 chr5:171416420-171416440 1.0000 20 chr7:139784872-139784892 1.0000 20 chr4:124697591-124697611 1.0000 20 chr13:50941116-50941136 1.0000 20 chr22:45650985-45651005 1.0000 20 chr20:19928707-19928727 1.0000 20 chr9:100062280-100062300 1.0000 20 chr2:25809750-25809770 1.0000 20 chr14:61796366-61796386 1.0000 20 chr5:56326201-56326221 1.0000 20 chr5:149869639-149869659 1.0000 20 chr8:18704595-18704615 1.0000 20 chr11:120483835-12048385 1.0000 20 chr15:48106436-48106456 1.0000 20 chr8:42046645-42046665 1.0000 20 chr5:158269108-158269128 1.0000 20 chr10:126303048-12630306 1.0000 20 chr11:87913324-87913344 1.0000 20 chr2:227849544-227849564 1.0000 20 chr14:70142945-70142965 1.0000 20 chr2:100752939-100752959 1.0000 20 chr6:118675990-118676010 1.0000 20 chr3:15092081-15092101 1.0000 20 chr16:23929163-23929183 1.0000 20 chr7:50484351-50484371 1.0000 20 chr2:42949891-42949911 1.0000 20 chr9:1536683-1536703 1.0000 20 chr20:14811330-14811350 1.0000 20 chr1:113574071-113574091 1.0000 20 chr12:65054544-65054564 1.0000 20 chr10:17274493-17274513 1.0000 20 chr2:213595939-213595959 1.0000 20 chr11:117869054-11786907 1.0000 20 chr2:149361333-149361353 1.0000 20 chr1:249088011-249088031 1.0000 20 chr5:78281604-78281624 1.0000 20 chr1:7278492-7278512 1.0000 20 chr12:12799006-12799026 1.0000 20 chr3:156777659-156777679 1.0000 20 chr17:60730947-60730967 1.0000 20 chr10:121255976-12125599 1.0000 20 chr1:206603859-206603879 1.0000 20 chr20:1516638-1516658 1.0000 20 chr2:208021771-208021791 1.0000 20 chr1:66865767-66865787 1.0000 20 chr11:48028384-48028404 1.0000 20 chr3:112692309-112692329 1.0000 20 chr18:13019453-13019473 1.0000 20 chr4:7015903-7015923 1.0000 20 chr12:105035878-10503589 1.0000 20 chr10:6183306-6183326 1.0000 20 chr7:10746668-10746688 1.0000 20 chr2:191587396-191587416 1.0000 20 chr5:60122687-60122707 1.0000 20 chr1:205569452-205569472 1.0000 20 chr4:100772327-100772347 1.0000 20 chr10:81026646-81026666 1.0000 20 chr12:919979-919999 1.0000 20 chr17:25566260-25566280 1.0000 20 chr3:149832855-149832875 1.0000 20 chr2:111858573-111858593 1.0000 20 chr2:240215892-240215912 1.0000 20 chr7:140376295-140376315 1.0000 20 chr7:36155317-36155337 1.0000 20 chr2:136422284-136422304 1.0000 20 chr17:48248520-48248540 1.0000 20 chr13:32505255-32505275 1.0000 20 chr15:101243459-10124347 1.0000 20 chr17:63653063-63653083 1.0000 20 chr2:208195762-208195782 1.0000 20 chr18:11004492-11004512 1.0000 20 chr16:11058855-11058875 1.0000 20 chr4:37893437-37893457 1.0000 20 chr6:20320282-20320302 1.0000 20 chr5:144436564-144436584 1.0000 20 chr17:19366659-19366679 1.0000 20 chr8:130564911-130564931 1.0000 20 chr6:68836424-68836444 1.0000 20 chr18:13893550-13893570 1.0000 20 chr11:43575510-43575530 1.0000 20 chr19:6947868-6947888 1.0000 20 chr9:132663238-132663258 1.0000 20 chr2:208087867-208087887 1.0000 20 chr2:142271597-142271617 1.0000 20 chr14:21136326-21136346 1.0000 20 chr4:104419618-104419638 1.0000 20 chr12:122430271-12243029 1.0000 20 chr3:150502326-150502346 1.0000 20 chr1:167469087-167469107 1.0000 20 chr6:42307867-42307887 1.0000 20 chr2:48475870-48475890 1.0000 20 chr2:148397561-148397581 1.0000 20 chr3:124295542-124295562 1.0000 20 chr12:52512407-52512427 1.0000 20 chr17:37275204-37275224 1.0000 20 chrX:128920444-128920464 1.0000 20 chr1:29289141-29289161 1.0000 20 chr5:148171059-148171079 1.0000 20 chr1:116932955-116932975 1.0000 20 chr14:69533638-69533658 1.0000 20 chr5:43245075-43245095 1.0000 20 chr12:76577477-76577497 1.0000 20 chr2:139469947-139469967 1.0000 20 chr10:49487273-49487293 1.0000 20 chr4:105887964-105887984 1.0000 20 chr3:61344313-61344333 1.0000 20 chr7:11372317-11372337 1.0000 20 chr2:20716883-20716903 1.0000 20 chr2:80757775-80757795 1.0000 20 chr9:97658184-97658204 1.0000 20 chr16:29655790-29655810 1.0000 20 chr2:38489237-38489257 1.0000 20 chr11:120796860-12079688 1.0000 20 chr13:43072101-43072121 1.0000 20 chr6:167567190-167567210 1.0000 20 chr18:53043839-53043859 1.0000 20 chr1:37754630-37754650 1.0000 20 chr16:48222569-48222589 1.0000 20 chr1:205309029-205309049 1.0000 20 chr5:169083264-169083284 1.0000 20 chr1:42265600-42265620 1.0000 20 chr2:149401125-149401145 1.0000 20 chr1:118438287-118438307 1.0000 20 chr20:3639731-3639751 1.0000 20 chr5:96430958-96430978 1.0000 20 chr3:194210769-194210789 1.0000 20 chr1:40652316-40652336 1.0000 20 chr15:74834351-74834371 1.0000 20 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/GM12878/inference_raw/MEME/RankLinear0.6_10_IRF4/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/IRF4.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 5000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 5000 norand= no csites= 1000 Letter frequencies in dataset: A 0.273 C 0.226 G 0.223 T 0.278 Background letter frequencies (from file dataset with add-one prior applied): A 0.273 C 0.226 G 0.223 T 0.278 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF TSASTCAT MEME-1 width = 8 sites = 66 llr = 460 E-value = 1.3e-045 ******************************************************************************** -------------------------------------------------------------------------------- Motif TSASTCAT MEME-1 Description -------------------------------------------------------------------------------- Simplified A ::9::1a1 pos.-specific C 13:4:9:1 probability G :6:5:::3 matrix T 911:a::6 bits 2.2 1.9 * 1.7 ** 1.5 * *** Relative 1.3 * *** Entropy 1.1 * * *** (10.1 bits) 0.9 ******* 0.6 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGAGTCAT consensus C C G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TSASTCAT MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr13:43072101-43072121 2 1.80e-05 T TGAGTCAT GGGCTACTGC chr7:36155317-36155337 3 1.80e-05 CC TGAGTCAT AAAGAAACCT chr2:149361333-149361353 9 1.80e-05 TTTAGAAG TGAGTCAT AGAG chr11:87913324-87913344 1 1.80e-05 . TGAGTCAT CTAGTATTGA chr2:20565322-20565342 13 1.80e-05 tgctcagctc tgagtcat chr11:4721121-4721141 1 1.80e-05 . TGAGTCAT CTACACCCAA chr6:73450042-73450062 12 1.80e-05 AGACCAAGTC TGAGTCAT T chr1:63087857-63087877 2 1.80e-05 c tgagtcat ttctgtcttc chr2:20716883-20716903 5 3.62e-05 ACAG TGACTCAT TTCAGAAG chr3:124295542-124295562 3 3.62e-05 TT TGACTCAT CAGAAACCTC chr4:104419618-104419638 8 3.62e-05 TAGTACA TGACTCAT GGCAG chr20:19928707-19928727 6 3.62e-05 CCAGA TGACTCAT GTAAGTA chr19:36202382-36202402 13 3.62e-05 CCTTTCGTTC TGACTCAT chr11:100796829-10079684 8 3.62e-05 CTTGTTA TGACTCAT CTGCC chr17:48360777-48360797 8 3.62e-05 cttgaaa tgactcat ttcaa chr1:167632349-167632369 1 3.62e-05 . TGACTCAT CTGGATCTTC chr2:47137052-47137072 2 3.62e-05 A TGACTCAT CTGGCAGCAC chr17:48248520-48248540 5 5.07e-05 AGTA Tgagtcag acacctgc chr12:65054544-65054564 11 5.07e-05 GGTTTTGCTT TGAGTCAG AA chr3:38548787-38548807 6 5.07e-05 tcata tgagtcag gaacgct chr1:28624516-28624536 12 5.07e-05 tctttgaagg tgagtcag a chr12:122430271-12243029 3 6.89e-05 GA TCAGTCAT ACGGGAAGAG chr9:132663238-132663258 13 8.35e-05 CTTAAAGCAG TGACTCAG chr11:120483835-12048385 3 8.35e-05 TG TGACTCag agagctcggg chr14:68147032-68147052 9 8.35e-05 TCTGGAAA TGACTCAG CCTT chr10:126303048-12630306 13 1.02e-04 TGGGAACAAA TCACTCAT chr2:218945981-218946001 12 1.02e-04 cagcccagat tcactcat c chr3:15092081-15092101 7 1.17e-04 AAGACT TCAGTCAG TTGGGT chr2:149401125-149401145 5 1.46e-04 TATT TGAGTCAC CTTGATTT chr6:68836424-68836444 3 1.46e-04 at tgagtcac atctctgcat chr8:37595312-37595332 12 1.46e-04 AGGCTGGATA TGAGTCAC T chr3:122252861-122252881 1 1.78e-04 . tgagtcaa ttggtgcagg chr1:236323950-236323970 11 1.93e-04 GCTCTTGAAT TGACTCAC TG chr2:98583565-98583585 3 1.93e-04 TT TGACTCAC CATAAAAGGG chr13:32505255-32505275 6 2.48e-04 AATGC TTAGTCAT ACCAAGA chr10:121255976-12125599 10 2.48e-04 ctgctgaaa tgactcaa acc chr5:116032272-116032292 7 2.48e-04 CAGGAA TTAGTCAT TCTGTT chr17:68133683-68133703 11 2.48e-04 CACAAAGCCC TGACTCAA TT chr1:113574071-113574091 6 2.82e-04 GTGCC TGTGTCAT AGTGAAA chr6:118675990-118676010 1 3.16e-04 . ttactcat tatacctcaa chr5:55273991-55274011 1 3.16e-04 . ttactcat aacagtagtc chr4:37893437-37893457 6 3.49e-04 CTGTA CCAGTCAT TTTGAAA chr18:13019453-13019473 1 3.49e-04 . CCAGTCAT TACATGAAAA chr13:50941116-50941136 11 3.49e-04 AACCTCTTCT CCAGTCAT CT chr11:102239381-10223940 13 3.49e-04 TAGCAGTCCT CCAGTCAT chr10:6183306-6183326 11 4.66e-04 GCAAGTTTGG TGAGTAAT AA chr10:81026646-81026666 3 5.22e-04 GA CCACTCAT TCCTGCTTTG chr1:42265600-42265620 7 6.28e-04 ACAGCA TTACTCAG GCCAAT chr17:63653063-63653083 12 6.28e-04 AAGAGAAGAT TCTGTCAT C chr1:40652316-40652336 7 7.32e-04 GTGGTT TCAGCCAT CATGTT chr3:156777659-156777679 8 7.32e-04 GAAATGT TCTCTCAT TCCTT chr7:139912463-139912483 8 7.32e-04 TATCTGC TGAGTAAG ATCGA chr3:194210769-194210789 1 8.01e-04 . ACAGTCAT ACCAGTAAGG chr2:208195762-208195782 7 8.01e-04 TAGAAA TGAATCAG TGCCCT chr1:209925489-209925509 10 8.01e-04 CACAAATGT ACAGTCAT AAC chr3:47267305-47267325 9 8.01e-04 cacgctga ccactcag gttt chr15:48106436-48106456 8 8.58e-04 CACTGAA TCAATCAT AGACC chr11:120580712-12058073 12 8.58e-04 caaagcatcg tgattCAT A chr1:167469087-167469107 2 9.54e-04 c tctgtcag taacagaggc chr2:208021771-208021791 7 9.54e-04 AAATCT TAAGTCAT AGTCAT chr11:66659808-66659828 3 9.54e-04 GA TGACTAAG AGCTTTTTCA chr10:49487273-49487293 9 1.09e-03 cagtgcag tcagccag agag chr5:158269108-158269128 11 1.09e-03 CACAGGACAA TCAGCCAG TC chr17:56582557-56582577 10 1.37e-03 ATCACATGC ACACTCAG CCA chr20:43213885-43213905 8 1.37e-03 TGTTTTG TGTGTCAA AGTTG chr4:113249238-113249258 5 2.06e-03 GCAA TGACTAAA AAAGAAAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TSASTCAT MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr13:43072101-43072121 1.8e-05 1_[+1]_11 chr7:36155317-36155337 1.8e-05 2_[+1]_10 chr2:149361333-149361353 1.8e-05 8_[+1]_4 chr11:87913324-87913344 1.8e-05 [+1]_12 chr2:20565322-20565342 1.8e-05 12_[+1] chr11:4721121-4721141 1.8e-05 [+1]_12 chr6:73450042-73450062 1.8e-05 11_[+1]_1 chr1:63087857-63087877 1.8e-05 1_[+1]_11 chr2:20716883-20716903 3.6e-05 4_[+1]_8 chr3:124295542-124295562 3.6e-05 2_[+1]_10 chr4:104419618-104419638 3.6e-05 7_[+1]_5 chr20:19928707-19928727 3.6e-05 5_[+1]_7 chr19:36202382-36202402 3.6e-05 12_[+1] chr11:100796829-10079684 3.6e-05 7_[+1]_5 chr17:48360777-48360797 3.6e-05 7_[+1]_5 chr1:167632349-167632369 3.6e-05 [+1]_12 chr2:47137052-47137072 3.6e-05 1_[+1]_11 chr17:48248520-48248540 5.1e-05 4_[+1]_8 chr12:65054544-65054564 5.1e-05 10_[+1]_2 chr3:38548787-38548807 5.1e-05 5_[+1]_7 chr1:28624516-28624536 5.1e-05 11_[+1]_1 chr12:122430271-12243029 6.9e-05 2_[+1]_10 chr9:132663238-132663258 8.4e-05 12_[+1] chr11:120483835-12048385 8.4e-05 2_[+1]_10 chr14:68147032-68147052 8.4e-05 8_[+1]_4 chr10:126303048-12630306 0.0001 12_[+1] chr2:218945981-218946001 0.0001 11_[+1]_1 chr3:15092081-15092101 0.00012 6_[+1]_6 chr2:149401125-149401145 0.00015 4_[+1]_8 chr6:68836424-68836444 0.00015 2_[+1]_10 chr8:37595312-37595332 0.00015 11_[+1]_1 chr3:122252861-122252881 0.00018 [+1]_12 chr1:236323950-236323970 0.00019 10_[+1]_2 chr2:98583565-98583585 0.00019 2_[+1]_10 chr13:32505255-32505275 0.00025 5_[+1]_7 chr10:121255976-12125599 0.00025 9_[+1]_3 chr5:116032272-116032292 0.00025 6_[+1]_6 chr17:68133683-68133703 0.00025 10_[+1]_2 chr1:113574071-113574091 0.00028 5_[+1]_7 chr6:118675990-118676010 0.00032 [+1]_12 chr5:55273991-55274011 0.00032 [+1]_12 chr4:37893437-37893457 0.00035 5_[+1]_7 chr18:13019453-13019473 0.00035 [+1]_12 chr13:50941116-50941136 0.00035 10_[+1]_2 chr11:102239381-10223940 0.00035 12_[+1] chr10:6183306-6183326 0.00047 10_[+1]_2 chr10:81026646-81026666 0.00052 2_[+1]_10 chr1:42265600-42265620 0.00063 6_[+1]_6 chr17:63653063-63653083 0.00063 11_[+1]_1 chr1:40652316-40652336 0.00073 6_[+1]_6 chr3:156777659-156777679 0.00073 7_[+1]_5 chr7:139912463-139912483 0.00073 7_[+1]_5 chr3:194210769-194210789 0.0008 [+1]_12 chr2:208195762-208195782 0.0008 6_[+1]_6 chr1:209925489-209925509 0.0008 9_[+1]_3 chr3:47267305-47267325 0.0008 8_[+1]_4 chr15:48106436-48106456 0.00086 7_[+1]_5 chr11:120580712-12058073 0.00086 11_[+1]_1 chr1:167469087-167469107 0.00095 1_[+1]_11 chr2:208021771-208021791 0.00095 6_[+1]_6 chr11:66659808-66659828 0.00095 2_[+1]_10 chr10:49487273-49487293 0.0011 8_[+1]_4 chr5:158269108-158269128 0.0011 10_[+1]_2 chr17:56582557-56582577 0.0014 9_[+1]_3 chr20:43213885-43213905 0.0014 7_[+1]_5 chr4:113249238-113249258 0.0021 4_[+1]_8 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TSASTCAT MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TSASTCAT width=8 seqs=66 chr13:43072101-43072121 ( 2) TGAGTCAT 1 chr7:36155317-36155337 ( 3) TGAGTCAT 1 chr2:149361333-149361353 ( 9) TGAGTCAT 1 chr11:87913324-87913344 ( 1) TGAGTCAT 1 chr2:20565322-20565342 ( 13) TGAGTCAT 1 chr11:4721121-4721141 ( 1) TGAGTCAT 1 chr6:73450042-73450062 ( 12) TGAGTCAT 1 chr1:63087857-63087877 ( 2) TGAGTCAT 1 chr2:20716883-20716903 ( 5) TGACTCAT 1 chr3:124295542-124295562 ( 3) TGACTCAT 1 chr4:104419618-104419638 ( 8) TGACTCAT 1 chr20:19928707-19928727 ( 6) TGACTCAT 1 chr19:36202382-36202402 ( 13) TGACTCAT 1 chr11:100796829-10079684 ( 8) TGACTCAT 1 chr17:48360777-48360797 ( 8) TGACTCAT 1 chr1:167632349-167632369 ( 1) TGACTCAT 1 chr2:47137052-47137072 ( 2) TGACTCAT 1 chr17:48248520-48248540 ( 5) TGAGTCAG 1 chr12:65054544-65054564 ( 11) TGAGTCAG 1 chr3:38548787-38548807 ( 6) TGAGTCAG 1 chr1:28624516-28624536 ( 12) TGAGTCAG 1 chr12:122430271-12243029 ( 3) TCAGTCAT 1 chr9:132663238-132663258 ( 13) TGACTCAG 1 chr11:120483835-12048385 ( 3) TGACTCAG 1 chr14:68147032-68147052 ( 9) TGACTCAG 1 chr10:126303048-12630306 ( 13) TCACTCAT 1 chr2:218945981-218946001 ( 12) TCACTCAT 1 chr3:15092081-15092101 ( 7) TCAGTCAG 1 chr2:149401125-149401145 ( 5) TGAGTCAC 1 chr6:68836424-68836444 ( 3) TGAGTCAC 1 chr8:37595312-37595332 ( 12) TGAGTCAC 1 chr3:122252861-122252881 ( 1) TGAGTCAA 1 chr1:236323950-236323970 ( 11) TGACTCAC 1 chr2:98583565-98583585 ( 3) TGACTCAC 1 chr13:32505255-32505275 ( 6) TTAGTCAT 1 chr10:121255976-12125599 ( 10) TGACTCAA 1 chr5:116032272-116032292 ( 7) TTAGTCAT 1 chr17:68133683-68133703 ( 11) TGACTCAA 1 chr1:113574071-113574091 ( 6) TGTGTCAT 1 chr6:118675990-118676010 ( 1) TTACTCAT 1 chr5:55273991-55274011 ( 1) TTACTCAT 1 chr4:37893437-37893457 ( 6) CCAGTCAT 1 chr18:13019453-13019473 ( 1) CCAGTCAT 1 chr13:50941116-50941136 ( 11) CCAGTCAT 1 chr11:102239381-10223940 ( 13) CCAGTCAT 1 chr10:6183306-6183326 ( 11) TGAGTAAT 1 chr10:81026646-81026666 ( 3) CCACTCAT 1 chr1:42265600-42265620 ( 7) TTACTCAG 1 chr17:63653063-63653083 ( 12) TCTGTCAT 1 chr1:40652316-40652336 ( 7) TCAGCCAT 1 chr3:156777659-156777679 ( 8) TCTCTCAT 1 chr7:139912463-139912483 ( 8) TGAGTAAG 1 chr3:194210769-194210789 ( 1) ACAGTCAT 1 chr2:208195762-208195782 ( 7) TGAATCAG 1 chr1:209925489-209925509 ( 10) ACAGTCAT 1 chr3:47267305-47267325 ( 9) CCACTCAG 1 chr15:48106436-48106456 ( 8) TCAATCAT 1 chr11:120580712-12058073 ( 12) TGATTCAT 1 chr1:167469087-167469107 ( 2) TCTGTCAG 1 chr2:208021771-208021791 ( 7) TAAGTCAT 1 chr11:66659808-66659828 ( 3) TGACTAAG 1 chr10:49487273-49487293 ( 9) TCAGCCAG 1 chr5:158269108-158269128 ( 11) TCAGCCAG 1 chr17:56582557-56582577 ( 10) ACACTCAG 1 chr20:43213885-43213905 ( 8) TGTGTCAA 1 chr4:113249238-113249258 ( 5) TGACTAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TSASTCAT MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 6.9542 E= 1.3e-045 -259 -131 -1269 164 -417 42 144 -187 176 -1269 -1269 -187 -317 86 129 -419 -1269 -231 -1269 178 -217 206 -1269 -1269 187 -1269 -1269 -1269 -185 -158 21 109 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TSASTCAT MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 66 E= 1.3e-045 0.045455 0.090909 0.000000 0.863636 0.015152 0.303030 0.606061 0.075758 0.924242 0.000000 0.000000 0.075758 0.030303 0.409091 0.545455 0.015152 0.000000 0.045455 0.000000 0.954545 0.060606 0.939394 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.075758 0.075758 0.257576 0.590909 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TSASTCAT MEME-1 regular expression -------------------------------------------------------------------------------- T[GC]A[GC]TCA[TG] -------------------------------------------------------------------------------- Time 2.23 secs. ******************************************************************************** ******************************************************************************** MOTIF GGAAVTGA MEME-2 width = 8 sites = 10 llr = 95 E-value = 7.5e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif GGAAVTGA MEME-2 Description -------------------------------------------------------------------------------- Simplified A ::aa2::7 pos.-specific C ::::4::: probability G aa::4:a3 matrix T :::::a:: bits 2.2 ** * 1.9 **** ** 1.7 **** ** 1.5 **** ** Relative 1.3 **** ** Entropy 1.1 **** *** (13.7 bits) 0.9 **** *** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GGAACTGA consensus G G sequence A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGAAVTGA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr20:3639731-3639751 9 2.82e-05 TGCCATGA GGAAGTGa gagc chr13:53495525-53495545 4 2.82e-05 AAG GGAACTGA AAGTCAGAA chr2:152697073-152697093 6 2.82e-05 CCATG GGAAGTGA AACAAGG chr7:7291561-7291581 9 2.82e-05 ACAAAAGG GGAACTGA AAGT chr1:65631468-65631488 1 2.82e-05 . GGAAGTGA GAGGAGTGGG chr18:72885171-72885191 3 2.82e-05 GA GGAACTGA AACTCTTAGA chr18:72519233-72519253 5 2.82e-05 atta ggaactga aagtgttg chr16:48222569-48222589 3 5.12e-05 ga ggaagtgg ctctgtaact chr5:169083264-169083284 11 8.23e-05 ttgcagatga ggaaatgg ag chr7:11372317-11372337 8 8.23e-05 atgaact ggaaatgg tctgt -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGAAVTGA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr20:3639731-3639751 2.8e-05 8_[+2]_4 chr13:53495525-53495545 2.8e-05 3_[+2]_9 chr2:152697073-152697093 2.8e-05 5_[+2]_7 chr7:7291561-7291581 2.8e-05 8_[+2]_4 chr1:65631468-65631488 2.8e-05 [+2]_12 chr18:72885171-72885191 2.8e-05 2_[+2]_10 chr18:72519233-72519253 2.8e-05 4_[+2]_8 chr16:48222569-48222589 5.1e-05 2_[+2]_10 chr5:169083264-169083284 8.2e-05 10_[+2]_2 chr7:11372317-11372337 8.2e-05 7_[+2]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGAAVTGA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GGAAVTGA width=8 seqs=10 chr20:3639731-3639751 ( 9) GGAAGTGA 1 chr13:53495525-53495545 ( 4) GGAACTGA 1 chr2:152697073-152697093 ( 6) GGAAGTGA 1 chr7:7291561-7291581 ( 9) GGAACTGA 1 chr1:65631468-65631488 ( 1) GGAAGTGA 1 chr18:72885171-72885191 ( 3) GGAACTGA 1 chr18:72519233-72519253 ( 5) GGAACTGA 1 chr16:48222569-48222589 ( 3) GGAAGTGG 1 chr5:169083264-169083284 ( 11) GGAAATGG 1 chr7:11372317-11372337 ( 8) GGAAATGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGAAVTGA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 9.2854 E= 7.5e-002 -997 -997 216 -997 -997 -997 216 -997 187 -997 -997 -997 187 -997 -997 -997 -45 82 84 -997 -997 -997 -997 185 -997 -997 216 -997 136 -997 43 -997 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGAAVTGA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 10 E= 7.5e-002 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.200000 0.400000 0.400000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.700000 0.000000 0.300000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GGAAVTGA MEME-2 regular expression -------------------------------------------------------------------------------- GGAA[CGA]TG[AG] -------------------------------------------------------------------------------- Time 2.95 secs. ******************************************************************************** ******************************************************************************** MOTIF TCAGTTCC MEME-3 width = 8 sites = 6 llr = 67 E-value = 1.8e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCAGTTCC MEME-3 Description -------------------------------------------------------------------------------- Simplified A ::a::::: pos.-specific C :a::::aa probability G :::a:::: matrix T a:::aa:: bits 2.2 * * ** 1.9 ******** 1.7 ******** 1.5 ******** Relative 1.3 ******** Entropy 1.1 ******** (16.0 bits) 0.9 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCAGTTCC consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAGTTCC MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr2:142271597-142271617 12 1.51e-05 ctgcctcctc tcagttcc t chr7:140376295-140376315 4 1.51e-05 GTT TCAGTTCC CCTTGCGGA chr20:1516638-1516658 13 1.51e-05 TGCTTGGCTT TCAGTTCC chr5:149869639-149869659 10 1.51e-05 TGGCCACTC TCAGTTCC CTT chr2:18093572-18093592 10 1.51e-05 TGCTTGCTT TCAGTTCC TCT chr3:3130847-3130867 11 1.51e-05 TAGTGTCCTT TCAGTTCC CT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAGTTCC MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:142271597-142271617 1.5e-05 11_[+3]_1 chr7:140376295-140376315 1.5e-05 3_[+3]_9 chr20:1516638-1516658 1.5e-05 12_[+3] chr5:149869639-149869659 1.5e-05 9_[+3]_3 chr2:18093572-18093592 1.5e-05 9_[+3]_3 chr3:3130847-3130867 1.5e-05 10_[+3]_2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAGTTCC MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCAGTTCC width=8 seqs=6 chr2:142271597-142271617 ( 12) TCAGTTCC 1 chr7:140376295-140376315 ( 4) TCAGTTCC 1 chr20:1516638-1516658 ( 13) TCAGTTCC 1 chr5:149869639-149869659 ( 10) TCAGTTCC 1 chr2:18093572-18093592 ( 10) TCAGTTCC 1 chr3:3130847-3130867 ( 11) TCAGTTCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAGTTCC MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.73685 E= 1.8e+000 -923 -923 -923 185 -923 214 -923 -923 187 -923 -923 -923 -923 -923 216 -923 -923 -923 -923 185 -923 -923 -923 185 -923 214 -923 -923 -923 214 -923 -923 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAGTTCC MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 6 E= 1.8e+000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCAGTTCC MEME-3 regular expression -------------------------------------------------------------------------------- TCAGTTCC -------------------------------------------------------------------------------- Time 3.79 secs. ******************************************************************************** ******************************************************************************** MOTIF TGACTGKG MEME-4 width = 8 sites = 16 llr = 129 E-value = 1.4e+000 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGACTGKG MEME-4 Description -------------------------------------------------------------------------------- Simplified A ::911::2 pos.-specific C :1:9:::: probability G :9:::a46 matrix T a:1:9:63 bits 2.2 * 1.9 * * 1.7 * * 1.5 ** *** Relative 1.3 ****** Entropy 1.1 ******* (11.7 bits) 0.9 ******* 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGACTGTG consensus GT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACTGKG MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:118438287-118438307 1 1.47e-05 . TGACTGTG ACTGCCTCAC chr8:8310325-8310345 2 1.47e-05 G TGACtgtg tgtgtgagtg chr6:106611980-106612000 13 2.65e-05 TTTCTGCTTA TGACTGGG chr9:6185240-6185260 11 4.48e-05 agtcaaggtt tgactgtt ac chr3:17088894-17088914 11 4.48e-05 ACTTTCAGAA TGACTGTT AG chr4:100772327-100772347 6 7.75e-05 CATTC TGACTGTA AAACTGT chr17:60730947-60730967 2 7.75e-05 A TGACTGGT GGGGGAAGCC chr22:45650985-45651005 3 7.75e-05 ta tgactgta ggctacagac chr10:101934671-10193469 3 7.75e-05 AA TGACTGGT GGTGAGACAA chr15:57079346-57079366 10 9.19e-05 ctctcgtta tgactgga gat chr9:97658184-97658204 7 1.22e-04 atgtat tgtctgtg gctgct chr11:43575510-43575530 6 1.40e-04 ATGAA TGAATGTG GTGGTGT chr2:136422284-136422304 7 1.40e-04 TTGTTA TGAATGTG AAACTA chr9:100062280-100062300 13 1.64e-04 tggtgttagt tcactggg chr1:116932955-116932975 13 1.92e-04 CAGAACCGGA TGACAGTG chr11:120796860-12079688 3 5.29e-04 CC TCTCTGGG CTTTGCCACA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACTGKG MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:118438287-118438307 1.5e-05 [+4]_12 chr8:8310325-8310345 1.5e-05 1_[+4]_11 chr6:106611980-106612000 2.6e-05 12_[+4] chr9:6185240-6185260 4.5e-05 10_[+4]_2 chr3:17088894-17088914 4.5e-05 10_[+4]_2 chr4:100772327-100772347 7.8e-05 5_[+4]_7 chr17:60730947-60730967 7.8e-05 1_[+4]_11 chr22:45650985-45651005 7.8e-05 2_[+4]_10 chr10:101934671-10193469 7.8e-05 2_[+4]_10 chr15:57079346-57079366 9.2e-05 9_[+4]_3 chr9:97658184-97658204 0.00012 6_[+4]_6 chr11:43575510-43575530 0.00014 5_[+4]_7 chr2:136422284-136422304 0.00014 6_[+4]_6 chr9:100062280-100062300 0.00016 12_[+4] chr1:116932955-116932975 0.00019 12_[+4] chr11:120796860-12079688 0.00053 2_[+4]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACTGKG MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGACTGKG width=8 seqs=16 chr1:118438287-118438307 ( 1) TGACTGTG 1 chr8:8310325-8310345 ( 2) TGACTGTG 1 chr6:106611980-106612000 ( 13) TGACTGGG 1 chr9:6185240-6185260 ( 11) TGACTGTT 1 chr3:17088894-17088914 ( 11) TGACTGTT 1 chr4:100772327-100772347 ( 6) TGACTGTA 1 chr17:60730947-60730967 ( 2) TGACTGGT 1 chr22:45650985-45651005 ( 3) TGACTGTA 1 chr10:101934671-10193469 ( 3) TGACTGGT 1 chr15:57079346-57079366 ( 10) TGACTGGA 1 chr9:97658184-97658204 ( 7) TGTCTGTG 1 chr11:43575510-43575530 ( 6) TGAATGTG 1 chr2:136422284-136422304 ( 7) TGAATGTG 1 chr9:100062280-100062300 ( 13) TCACTGGG 1 chr1:116932955-116932975 ( 13) TGACAGTG 1 chr11:120796860-12079688 ( 3) TCTCTGGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACTGKG MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.39892 E= 1.4e+000 -1064 -1064 -1064 185 -1064 -85 197 -1064 168 -1064 -1064 -115 -113 195 -1064 -1064 -213 -1064 -1064 175 -1064 -1064 217 -1064 -1064 -1064 75 117 -54 -1064 134 -15 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACTGKG MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 16 E= 1.4e+000 0.000000 0.000000 0.000000 1.000000 0.000000 0.125000 0.875000 0.000000 0.875000 0.000000 0.000000 0.125000 0.125000 0.875000 0.000000 0.000000 0.062500 0.000000 0.000000 0.937500 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.375000 0.625000 0.187500 0.000000 0.562500 0.250000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGACTGKG MEME-4 regular expression -------------------------------------------------------------------------------- TGACTG[TG][GT] -------------------------------------------------------------------------------- Time 4.50 secs. ******************************************************************************** ******************************************************************************** MOTIF CAAARVCA MEME-5 width = 8 sites = 18 llr = 134 E-value = 7.4e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CAAARVCA MEME-5 Description -------------------------------------------------------------------------------- Simplified A :a6a43:7 pos.-specific C a:1::493 probability G ::3:621: matrix T :::::1:: bits 2.2 * 1.9 ** * 1.7 ** * * 1.5 ** * * Relative 1.3 ** * * Entropy 1.1 ** ** ** (10.7 bits) 0.9 ** ** ** 0.6 ***** ** 0.4 ***** ** 0.2 ******** 0.0 -------- Multilevel CAAAGCCA consensus G AA C sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAAARVCA MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr15:79965939-79965959 5 1.43e-05 TCCG CAAAGCCA CAGCAGGG chr12:52512407-52512427 8 2.60e-05 tgagcat cagagcca tacac chr1:66865767-66865787 2 4.32e-05 G CAAAGACA CTCACAAAGT chr2:191587396-191587416 11 8.67e-05 TGATCATCTG CAAAGGCA AC chr1:249088011-249088031 9 8.67e-05 aaatctgc caaaacca ccat chr20:3400975-3400995 1 8.67e-05 . CAAAACCA CACTAAGCAC chr5:99501210-99501230 6 8.67e-05 ttcag caaaacca cacatta chr17:68133683-68133703 3 8.67e-05 CA CAAAGCCC TGACTCAATT chr5:60122687-60122707 2 2.56e-04 c cagaaaca ttttaggtac chr1:167469087-167469107 13 2.91e-04 ctgtcagtaa cagaggcc chr8:74748081-74748101 6 2.91e-04 taatt cagaggcc ttcatag chr17:48468970-48468990 1 3.37e-04 . cacagaca atagttgtct chr10:329942-329962 4 3.37e-04 AGT CAAAGCGA TAGCCACGT chr6:42307867-42307887 2 3.88e-04 T CACAACCA AACAACCATT chr7:37758880-37758900 3 3.88e-04 TG CAAAAGCC AGGGCTTTGT chr17:8842933-8842953 4 4.05e-04 tga caaagtca caggtgcta chr3:124295542-124295562 11 4.31e-04 TTTGACTCAT CAGAAACC TC chr17:25566260-25566280 13 4.60e-04 AGTGTCAATT CAAAGAGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAAARVCA MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr15:79965939-79965959 1.4e-05 4_[+5]_8 chr12:52512407-52512427 2.6e-05 7_[+5]_5 chr1:66865767-66865787 4.3e-05 1_[+5]_11 chr2:191587396-191587416 8.7e-05 10_[+5]_2 chr1:249088011-249088031 8.7e-05 8_[+5]_4 chr20:3400975-3400995 8.7e-05 [+5]_12 chr5:99501210-99501230 8.7e-05 5_[+5]_7 chr17:68133683-68133703 8.7e-05 2_[+5]_10 chr5:60122687-60122707 0.00026 1_[+5]_11 chr1:167469087-167469107 0.00029 12_[+5] chr8:74748081-74748101 0.00029 5_[+5]_7 chr17:48468970-48468990 0.00034 [+5]_12 chr10:329942-329962 0.00034 3_[+5]_9 chr6:42307867-42307887 0.00039 1_[+5]_11 chr7:37758880-37758900 0.00039 2_[+5]_10 chr17:8842933-8842953 0.00041 3_[+5]_9 chr3:124295542-124295562 0.00043 10_[+5]_2 chr17:25566260-25566280 0.00046 12_[+5] -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAAARVCA MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CAAARVCA width=8 seqs=18 chr15:79965939-79965959 ( 5) CAAAGCCA 1 chr12:52512407-52512427 ( 8) CAGAGCCA 1 chr1:66865767-66865787 ( 2) CAAAGACA 1 chr2:191587396-191587416 ( 11) CAAAGGCA 1 chr1:249088011-249088031 ( 9) CAAAACCA 1 chr20:3400975-3400995 ( 1) CAAAACCA 1 chr5:99501210-99501230 ( 6) CAAAACCA 1 chr17:68133683-68133703 ( 3) CAAAGCCC 1 chr5:60122687-60122707 ( 2) CAGAAACA 1 chr1:167469087-167469107 ( 13) CAGAGGCC 1 chr8:74748081-74748101 ( 6) CAGAGGCC 1 chr17:48468970-48468990 ( 1) CACAGACA 1 chr10:329942-329962 ( 4) CAAAGCGA 1 chr6:42307867-42307887 ( 2) CACAACCA 1 chr7:37758880-37758900 ( 3) CAAAAGCC 1 chr17:8842933-8842953 ( 4) CAAAGTCA 1 chr3:124295542-124295562 ( 11) CAGAAACC 1 chr17:25566260-25566280 ( 13) CAAAGAGA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAAARVCA MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 7.6233 E= 7.4e+002 -1081 214 -1081 -1081 187 -1081 -1081 -1081 116 -102 32 -1081 187 -1081 -1081 -1081 51 -1081 146 -1081 2 98 0 -232 -1081 197 -100 -1081 140 30 -1081 -1081 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAAARVCA MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 18 E= 7.4e+002 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.611111 0.111111 0.277778 0.000000 1.000000 0.000000 0.000000 0.000000 0.388889 0.000000 0.611111 0.000000 0.277778 0.444444 0.222222 0.055556 0.000000 0.888889 0.111111 0.000000 0.722222 0.277778 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAAARVCA MEME-5 regular expression -------------------------------------------------------------------------------- CA[AG]A[GA][CAG]C[AC] -------------------------------------------------------------------------------- Time 5.28 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:89449088-89449108 1.59e-01 20 chr6:150739448-150739468 6.32e-02 20 chr11:133847074-13384709 3.45e-01 20 chr4:146950469-146950489 7.91e-01 20 chr3:122252861-122252881 2.15e-02 20 chr20:53250594-53250614 2.33e-02 20 chr18:10838794-10838814 3.01e-01 20 chr8:134165329-134165349 1.88e-01 20 chr2:216910019-216910039 8.96e-01 20 chr2:218945981-218946001 8.24e-03 20 chr14:68147032-68147052 2.13e-04 3_[+2(6.83e-05)]_9 chr6:14666316-14666336 1.77e-01 20 chr8:26105966-26105986 8.77e-01 20 chr18:72519233-72519253 1.68e-03 4_[+2(2.82e-05)]_8 chr6:116038404-116038424 5.15e-02 20 chr2:47137052-47137072 2.13e-02 1_[+1(3.62e-05)]_11 chr2:175257617-175257637 3.77e-01 20 chr11:115456277-11545629 3.20e-01 20 chr7:133977991-133978011 4.03e-01 20 chr4:187055600-187055620 1.59e-01 20 chr18:13375448-13375468 3.95e-01 20 chr21:43925386-43925406 4.35e-01 20 chr3:155213395-155213415 1.45e-01 20 chr1:167632349-167632369 1.31e-02 [+1(3.62e-05)]_12 chr17:48360777-48360797 2.62e-04 7_[+1(3.62e-05)]_5 chr20:9596965-9596985 2.80e-01 20 chr2:10054965-10054985 1.60e-01 20 chr15:57833102-57833122 7.46e-01 20 chr17:68133683-68133703 5.13e-04 2_[+5(8.67e-05)]_10 chr7:139912463-139912483 1.13e-01 20 chr19:1904482-1904502 6.76e-01 20 chr18:72885171-72885191 2.71e-02 2_[+2(2.82e-05)]_10 chr1:65631468-65631488 1.96e-02 [+2(2.82e-05)]_12 chr11:102239381-10223940 7.75e-02 20 chr11:108094770-10809479 2.34e-01 20 chr2:12641767-12641787 4.60e-01 20 chr18:34218378-34218398 3.13e-01 20 chr10:101934671-10193469 5.52e-03 2_[+4(7.75e-05)]_10 chr2:75539308-75539328 8.47e-02 20 chr22:40446415-40446435 4.25e-01 20 chr21:38531504-38531524 4.48e-01 20 chr10:6178422-6178442 2.59e-01 20 chr11:100796829-10079684 1.51e-02 7_[+1(3.62e-05)]_5 chr2:207802450-207802470 5.58e-01 20 chr10:329942-329962 2.33e-02 20 chr15:57079346-57079366 1.37e-01 9_[+4(9.19e-05)]_3 chr3:17088894-17088914 1.60e-03 10_[+4(4.48e-05)]_2 chr17:62151887-62151907 7.93e-01 20 chr1:63087857-63087877 1.03e-03 1_[+1(1.80e-05)]_11 chr3:112770246-112770266 7.21e-01 20 chr6:73450042-73450062 4.34e-03 11_[+1(1.80e-05)]_1 chr17:78232785-78232805 9.09e-01 20 chr5:167676236-167676256 4.80e-01 20 chr21:36423041-36423061 7.09e-01 20 chr3:3130847-3130867 2.64e-03 10_[+3(1.51e-05)]_2 chr15:101679306-10167932 1.34e-01 20 chr2:18093572-18093592 1.39e-02 9_[+3(1.51e-05)]_3 chr2:8256990-8257010 5.81e-01 20 chr11:4721121-4721141 1.62e-02 [+1(1.80e-05)]_12 chr2:98583565-98583585 4.97e-02 20 chr15:79965939-79965959 9.43e-03 4_[+5(1.43e-05)]_8 chr19:36202382-36202402 7.97e-03 12_[+1(3.62e-05)] chr8:8310325-8310345 1.39e-02 1_[+4(1.47e-05)]_11 chr3:47267305-47267325 9.35e-02 20 chr1:209925489-209925509 9.13e-02 20 chr8:37595312-37595332 2.85e-03 20 chr10:32438249-32438269 5.14e-01 20 chr5:55273991-55274011 3.89e-02 20 chr9:109935368-109935388 6.37e-01 20 chr8:39706382-39706402 8.34e-01 20 chr20:43213885-43213905 3.34e-02 20 chr5:116032272-116032292 2.74e-02 20 chr2:204736403-204736423 2.86e-01 20 chr7:7291561-7291581 1.82e-02 8_[+2(2.82e-05)]_4 chr17:8842933-8842953 1.33e-03 20 chr5:179293877-179293897 9.67e-01 20 chr15:50682887-50682907 6.89e-02 20 chr19:19521767-19521787 2.87e-01 20 chr5:123860424-123860444 5.08e-01 20 chr1:159091942-159091962 6.60e-02 20 chr3:127481556-127481576 3.30e-01 20 chr17:56582557-56582577 6.02e-02 20 chr20:30866339-30866359 8.89e-01 20 chr8:74748081-74748101 1.91e-02 20 chr11:128627958-12862797 4.34e-01 20 chr11:66659808-66659828 7.37e-02 20 chr5:172117437-172117457 2.18e-01 20 chr4:24858322-24858342 4.53e-01 20 chr17:48468970-48468990 1.36e-01 20 chr12:132258277-13225829 5.89e-01 20 chr5:99501210-99501230 2.36e-02 5_[+5(8.67e-05)]_7 chr11:120580712-12058073 2.00e-01 20 chr15:59691831-59691851 5.36e-01 20 chr4:113249238-113249258 1.13e-01 20 chr4:6425515-6425535 7.87e-01 20 chr18:74775368-74775388 7.91e-02 20 chr18:42289921-42289941 3.86e-02 20 chr1:236323950-236323970 6.54e-03 20 chr7:20257120-20257140 5.59e-01 20 chr12:92172815-92172835 1.35e-01 20 chr2:20565322-20565342 5.56e-04 12_[+1(1.80e-05)] chr1:200849611-200849631 8.97e-01 20 chr9:6185240-6185260 2.79e-02 10_[+4(4.48e-05)]_2 chr5:123919624-123919644 5.55e-01 20 chr3:108012883-108012903 5.67e-01 20 chr12:105324617-10532463 8.46e-01 20 chr1:28624516-28624536 2.15e-03 11_[+1(5.07e-05)]_1 chr2:38374196-38374216 5.39e-01 20 chr6:106611980-106612000 4.32e-02 12_[+4(2.65e-05)] chr7:37758880-37758900 3.73e-02 20 chr19:10987521-10987541 3.61e-01 20 chr10:27026869-27026889 2.48e-01 20 chr10:11117008-11117028 6.95e-01 20 chr2:152697073-152697093 2.71e-02 5_[+2(2.82e-05)]_7 chr3:197588284-197588304 3.08e-01 20 chr13:53495525-53495545 7.94e-04 3_[+2(2.82e-05)]_9 chr10:73734406-73734426 4.27e-01 20 chr9:5510502-5510522 8.14e-02 20 chr3:38548787-38548807 3.21e-03 5_[+1(5.07e-05)]_7 chr20:3400975-3400995 2.51e-02 [+5(8.67e-05)]_12 chr12:96896524-96896544 4.52e-01 20 chr9:102574115-102574135 8.46e-01 20 chr5:171416420-171416440 3.93e-01 20 chr7:139784872-139784892 1.45e-01 20 chr4:124697591-124697611 5.15e-01 20 chr13:50941116-50941136 9.10e-02 20 chr22:45650985-45651005 5.79e-02 2_[+4(7.75e-05)]_10 chr20:19928707-19928727 2.95e-03 5_[+1(3.62e-05)]_7 chr9:100062280-100062300 3.05e-02 20 chr2:25809750-25809770 1.28e-01 20 chr14:61796366-61796386 5.74e-02 20 chr5:56326201-56326221 5.82e-01 20 chr5:149869639-149869659 2.27e-04 9_[+3(1.51e-05)]_3 chr8:18704595-18704615 9.90e-01 20 chr11:120483835-12048385 1.80e-03 2_[+1(8.35e-05)]_10 chr15:48106436-48106456 4.15e-02 20 chr8:42046645-42046665 9.02e-01 20 chr5:158269108-158269128 1.10e-01 20 chr10:126303048-12630306 7.18e-03 20 chr11:87913324-87913344 2.01e-02 [+1(1.80e-05)]_12 chr2:227849544-227849564 2.09e-02 20 chr14:70142945-70142965 3.50e-01 20 chr2:100752939-100752959 1.10e-01 20 chr6:118675990-118676010 2.16e-01 20 chr3:15092081-15092101 6.39e-03 20 chr16:23929163-23929183 4.62e-01 20 chr7:50484351-50484371 6.48e-01 20 chr2:42949891-42949911 3.28e-01 20 chr9:1536683-1536703 6.89e-01 20 chr20:14811330-14811350 2.41e-01 20 chr1:113574071-113574091 3.60e-03 20 chr12:65054544-65054564 5.64e-02 10_[+1(5.07e-05)]_2 chr10:17274493-17274513 1.37e-01 20 chr2:213595939-213595959 5.38e-01 20 chr11:117869054-11786907 5.65e-01 20 chr2:149361333-149361353 1.28e-03 8_[+1(1.80e-05)]_4 chr1:249088011-249088031 2.44e-02 8_[+5(8.67e-05)]_4 chr5:78281604-78281624 5.87e-01 20 chr1:7278492-7278512 3.20e-01 20 chr12:12799006-12799026 1.28e-01 20 chr3:156777659-156777679 1.61e-01 20 chr17:60730947-60730967 3.43e-02 1_[+4(7.75e-05)]_11 chr10:121255976-12125599 2.87e-03 20 chr1:206603859-206603879 4.89e-01 20 chr20:1516638-1516658 1.29e-02 12_[+3(1.51e-05)] chr2:208021771-208021791 5.81e-02 20 chr1:66865767-66865787 2.52e-03 1_[+5(4.32e-05)]_11 chr11:48028384-48028404 3.83e-01 20 chr3:112692309-112692329 7.37e-01 20 chr18:13019453-13019473 1.07e-01 20 chr4:7015903-7015923 1.66e-01 20 chr12:105035878-10503589 3.45e-01 20 chr10:6183306-6183326 1.41e-01 20 chr7:10746668-10746688 3.12e-01 20 chr2:191587396-191587416 1.56e-02 10_[+5(8.67e-05)]_2 chr5:60122687-60122707 7.95e-02 20 chr1:205569452-205569472 7.18e-02 20 chr4:100772327-100772347 3.01e-02 5_[+4(7.75e-05)]_7 chr10:81026646-81026666 1.75e-01 20 chr12:919979-919999 1.42e-01 20 chr17:25566260-25566280 2.76e-03 20 chr3:149832855-149832875 3.78e-01 20 chr2:111858573-111858593 7.93e-01 20 chr2:240215892-240215912 2.69e-02 20 chr7:140376295-140376315 9.92e-03 3_[+3(1.51e-05)]_9 chr7:36155317-36155337 1.34e-02 2_[+1(1.80e-05)]_10 chr2:136422284-136422304 3.35e-02 20 chr17:48248520-48248540 4.00e-03 4_[+1(5.07e-05)]_8 chr13:32505255-32505275 1.51e-01 20 chr15:101243459-10124347 1.74e-01 20 chr17:63653063-63653083 2.69e-01 20 chr2:208195762-208195782 4.18e-05 20 chr18:11004492-11004512 6.69e-01 20 chr16:11058855-11058875 8.86e-01 20 chr4:37893437-37893457 5.64e-02 20 chr6:20320282-20320302 7.17e-01 20 chr5:144436564-144436584 3.75e-02 20 chr17:19366659-19366679 6.43e-01 20 chr8:130564911-130564931 2.71e-01 20 chr6:68836424-68836444 2.02e-02 20 chr18:13893550-13893570 7.93e-01 20 chr11:43575510-43575530 3.91e-02 20 chr19:6947868-6947888 1.71e-01 20 chr9:132663238-132663258 1.94e-03 12_[+1(8.35e-05)] chr2:208087867-208087887 9.20e-01 20 chr2:142271597-142271617 3.73e-04 11_[+3(1.51e-05)]_1 chr14:21136326-21136346 3.14e-01 20 chr4:104419618-104419638 1.02e-02 7_[+1(3.62e-05)]_5 chr12:122430271-12243029 3.68e-02 2_[+1(6.89e-05)]_10 chr3:150502326-150502346 3.12e-01 20 chr1:167469087-167469107 1.28e-05 20 chr6:42307867-42307887 4.75e-02 20 chr2:48475870-48475890 4.76e-01 20 chr2:148397561-148397581 8.74e-01 20 chr3:124295542-124295562 3.34e-04 2_[+1(3.62e-05)]_10 chr12:52512407-52512427 2.17e-04 7_[+5(2.60e-05)]_5 chr17:37275204-37275224 4.68e-01 20 chrX:128920444-128920464 5.14e-01 20 chr1:29289141-29289161 9.26e-01 20 chr5:148171059-148171079 2.93e-01 20 chr1:116932955-116932975 3.66e-04 20 chr14:69533638-69533658 2.52e-01 20 chr5:43245075-43245095 8.40e-01 20 chr12:76577477-76577497 8.97e-02 20 chr2:139469947-139469967 5.28e-01 20 chr10:49487273-49487293 1.98e-01 20 chr4:105887964-105887984 5.51e-01 20 chr3:61344313-61344333 8.41e-01 20 chr7:11372317-11372337 8.57e-02 7_[+2(8.23e-05)]_5 chr2:20716883-20716903 1.80e-03 4_[+1(3.62e-05)]_8 chr2:80757775-80757795 6.48e-01 20 chr9:97658184-97658204 4.14e-02 20 chr16:29655790-29655810 6.20e-01 20 chr2:38489237-38489257 7.22e-01 20 chr11:120796860-12079688 7.19e-02 20 chr13:43072101-43072121 1.45e-02 1_[+1(1.80e-05)]_11 chr6:167567190-167567210 5.00e-01 20 chr18:53043839-53043859 3.69e-01 20 chr1:37754630-37754650 2.95e-01 20 chr16:48222569-48222589 2.29e-03 2_[+2(5.12e-05)]_10 chr1:205309029-205309049 4.39e-01 20 chr5:169083264-169083284 4.34e-02 10_[+2(8.23e-05)]_2 chr1:42265600-42265620 4.71e-02 20 chr2:149401125-149401145 4.79e-02 20 chr1:118438287-118438307 4.11e-03 [+4(1.47e-05)]_12 chr20:3639731-3639751 2.59e-02 8_[+2(2.82e-05)]_4 chr5:96430958-96430978 2.62e-01 20 chr3:194210769-194210789 1.60e-01 20 chr1:40652316-40652336 2.79e-01 20 chr15:74834351-74834371 3.41e-01 20 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n05.farnam.hpc.yale.internal ********************************************************************************