******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/IKZF1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr2:7806238-7806258 1.0000 20 chr18:49254302-49254322 1.0000 20 chr6:106593693-106593713 1.0000 20 chr9:6133868-6133888 1.0000 20 chr2:178412032-178412052 1.0000 20 chr12:93830061-93830081 1.0000 20 chr2:47212411-47212431 1.0000 20 chr14:21093766-21093786 1.0000 20 chr12:54635080-54635100 1.0000 20 chr3:149294241-149294261 1.0000 20 chr1:206890878-206890898 1.0000 20 chr1:213155175-213155195 1.0000 20 chr1:34996030-34996050 1.0000 20 chr1:59479084-59479104 1.0000 20 chr2:45060803-45060823 1.0000 20 chr20:43275006-43275026 1.0000 20 chr4:6944108-6944128 1.0000 20 chr2:33719565-33719585 1.0000 20 chr1:82014853-82014873 1.0000 20 chr1:111177621-111177641 1.0000 20 chr6:27599425-27599445 1.0000 20 chr1:204548095-204548115 1.0000 20 chr12:123205818-12320583 1.0000 20 chrX:118816447-118816467 1.0000 20 chr14:55197136-55197156 1.0000 20 chr22:40895266-40895286 1.0000 20 chr18:42380184-42380204 1.0000 20 chr1:85461725-85461745 1.0000 20 chr2:20776703-20776723 1.0000 20 chr6:112314298-112314318 1.0000 20 chr13:103831784-10383180 1.0000 20 chr20:10434097-10434117 1.0000 20 chr7:50304722-50304742 1.0000 20 chr10:92180629-92180649 1.0000 20 chr1:159808712-159808732 1.0000 20 chr3:121810505-121810525 1.0000 20 chr6:128921738-128921758 1.0000 20 chr5:111482211-111482231 1.0000 20 chr6:28510743-28510763 1.0000 20 chr5:50007322-50007342 1.0000 20 chr1:45142425-45142445 1.0000 20 chr19:17447761-17447781 1.0000 20 chr20:62359932-62359952 1.0000 20 chr7:142531297-142531317 1.0000 20 chr6:26556980-26557000 1.0000 20 chr5:142600517-142600537 1.0000 20 chr12:125424776-12542479 1.0000 20 chr5:112265520-112265540 1.0000 20 chr16:10300142-10300162 1.0000 20 chr2:161080699-161080719 1.0000 20 chr8:82045189-82045209 1.0000 20 chr6:31705878-31705898 1.0000 20 chr6:16636500-16636520 1.0000 20 chr10:125919599-12591961 1.0000 20 chr17:44217132-44217152 1.0000 20 chr1:12120083-12120103 1.0000 20 chr11:7555333-7555353 1.0000 20 chr7:37805688-37805708 1.0000 20 chr14:95986174-95986194 1.0000 20 chr16:10965473-10965493 1.0000 20 chr6:16471302-16471322 1.0000 20 chr5:88649731-88649751 1.0000 20 chr1:117312494-117312514 1.0000 20 chr1:172307709-172307729 1.0000 20 chr11:126058665-12605868 1.0000 20 chr16:15993591-15993611 1.0000 20 chr1:207140970-207140990 1.0000 20 chr14:53576043-53576063 1.0000 20 chr4:79578399-79578419 1.0000 20 chr6:10532049-10532069 1.0000 20 chr15:64263355-64263375 1.0000 20 chr8:126660635-126660655 1.0000 20 chr6:88433197-88433217 1.0000 20 chr8:102920627-102920647 1.0000 20 chrX:13031921-13031941 1.0000 20 chr3:46340998-46341018 1.0000 20 chr13:41163917-41163937 1.0000 20 chr1:212392389-212392409 1.0000 20 chr11:9271870-9271890 1.0000 20 chrX:106918023-106918043 1.0000 20 chr5:73497524-73497544 1.0000 20 chr7:43796472-43796492 1.0000 20 chr2:17996853-17996873 1.0000 20 chr3:127455201-127455221 1.0000 20 chr14:68751779-68751799 1.0000 20 chr5:171606709-171606729 1.0000 20 chr1:247570760-247570780 1.0000 20 chr17:8091195-8091215 1.0000 20 chr20:52228301-52228321 1.0000 20 chr4:152803790-152803810 1.0000 20 chr2:58266505-58266525 1.0000 20 chr1:109709954-109709974 1.0000 20 chr1:9097640-9097660 1.0000 20 chr8:141519400-141519420 1.0000 20 chr2:202845294-202845314 1.0000 20 chr4:77119884-77119904 1.0000 20 chr18:10928181-10928201 1.0000 20 chr12:108729666-10872968 1.0000 20 chr1:183871276-183871296 1.0000 20 chr1:245108671-245108691 1.0000 20 chr11:95289646-95289666 1.0000 20 chr8:8483387-8483407 1.0000 20 chr6:100619997-100620017 1.0000 20 chr17:33379051-33379071 1.0000 20 chr8:119971336-119971356 1.0000 20 chr9:27489232-27489252 1.0000 20 chr5:55391625-55391645 1.0000 20 chr11:77160198-77160218 1.0000 20 chr18:56209134-56209154 1.0000 20 chr15:64283981-64284001 1.0000 20 chr20:1516576-1516596 1.0000 20 chr4:40765457-40765477 1.0000 20 chr19:6528921-6528941 1.0000 20 chr12:116632812-11663283 1.0000 20 chr13:41634718-41634738 1.0000 20 chr17:62159634-62159654 1.0000 20 chr8:105290916-105290936 1.0000 20 chr1:234980347-234980367 1.0000 20 chr11:7542459-7542479 1.0000 20 chr1:32423552-32423572 1.0000 20 chr8:105598113-105598133 1.0000 20 chrX:114851559-114851579 1.0000 20 chr1:59473673-59473693 1.0000 20 chr17:46560924-46560944 1.0000 20 chr4:40625235-40625255 1.0000 20 chr11:115866905-11586692 1.0000 20 chr19:38494334-38494354 1.0000 20 chr22:31102029-31102049 1.0000 20 chr6:149401110-149401130 1.0000 20 chr6:52217345-52217365 1.0000 20 chr15:89710639-89710659 1.0000 20 chr17:53514642-53514662 1.0000 20 chr16:12638112-12638132 1.0000 20 chr18:56209370-56209390 1.0000 20 chr15:60843557-60843577 1.0000 20 chr2:28497947-28497967 1.0000 20 chr1:42421354-42421374 1.0000 20 chr20:52517156-52517176 1.0000 20 chr7:83428024-83428044 1.0000 20 chr3:143388327-143388347 1.0000 20 chr19:39074557-39074577 1.0000 20 chr4:152808801-152808821 1.0000 20 chr2:231818700-231818720 1.0000 20 chr6:13230107-13230127 1.0000 20 chr7:136044189-136044209 1.0000 20 chr1:12494317-12494337 1.0000 20 chr1:213102023-213102043 1.0000 20 chr3:196254744-196254764 1.0000 20 chr1:161676344-161676364 1.0000 20 chr3:142877627-142877647 1.0000 20 chr16:87814432-87814452 1.0000 20 chr6:88435156-88435176 1.0000 20 chr3:119114922-119114942 1.0000 20 chr12:111837315-11183733 1.0000 20 chr20:35994919-35994939 1.0000 20 chr7:2446635-2446655 1.0000 20 chr5:158832873-158832893 1.0000 20 chr11:75584513-75584533 1.0000 20 chr1:42421553-42421573 1.0000 20 chr14:65647193-65647213 1.0000 20 chr16:56979150-56979170 1.0000 20 chr17:16878850-16878870 1.0000 20 chr21:26768789-26768809 1.0000 20 chr11:128283174-12828319 1.0000 20 chr11:117917490-11791751 1.0000 20 chr2:218083670-218083690 1.0000 20 chr3:121952557-121952577 1.0000 20 chr4:185342377-185342397 1.0000 20 chr20:47406823-47406843 1.0000 20 chr10:104405704-10440572 1.0000 20 chr1:234382717-234382737 1.0000 20 chrX:29574183-29574203 1.0000 20 chr6:53104483-53104503 1.0000 20 chr15:59665181-59665201 1.0000 20 chr17:40808175-40808195 1.0000 20 chr6:143193130-143193150 1.0000 20 chr9:129916847-129916867 1.0000 20 chr22:40832589-40832609 1.0000 20 chr20:48955482-48955502 1.0000 20 chr12:112621255-11262127 1.0000 20 chr9:112680929-112680949 1.0000 20 chr6:119765947-119765967 1.0000 20 chr3:185255364-185255384 1.0000 20 chr16:10336929-10336949 1.0000 20 chr1:160681486-160681506 1.0000 20 chr3:50661866-50661886 1.0000 20 chr16:29674182-29674202 1.0000 20 chr8:61816559-61816579 1.0000 20 chr1:172327768-172327788 1.0000 20 chr1:236047137-236047157 1.0000 20 chr10:98047149-98047169 1.0000 20 chr21:30720772-30720792 1.0000 20 chr19:6556613-6556633 1.0000 20 chr11:72865477-72865497 1.0000 20 chr21:19157117-19157137 1.0000 20 chr14:51144403-51144423 1.0000 20 chr10:125312831-12531285 1.0000 20 chr12:92757695-92757715 1.0000 20 chr17:56698653-56698673 1.0000 20 chr19:4369345-4369365 1.0000 20 chr2:45918423-45918443 1.0000 20 chr11:102216755-10221677 1.0000 20 chr2:37828148-37828168 1.0000 20 chrX:13002988-13003008 1.0000 20 chr1:150135525-150135545 1.0000 20 chr11:123135316-12313533 1.0000 20 chr6:137040933-137040953 1.0000 20 chr15:66194918-66194938 1.0000 20 chr3:34098728-34098748 1.0000 20 chr5:88638432-88638452 1.0000 20 chr9:5459452-5459472 1.0000 20 chr10:11289143-11289163 1.0000 20 chr12:54758390-54758410 1.0000 20 chr2:238578424-238578444 1.0000 20 chr1:182592391-182592411 1.0000 20 chr17:43380286-43380306 1.0000 20 chr22:40297064-40297084 1.0000 20 chr12:65019468-65019488 1.0000 20 chr14:61992175-61992195 1.0000 20 chr6:135329725-135329745 1.0000 20 chr8:42623742-42623762 1.0000 20 chr8:52874917-52874937 1.0000 20 chr6:166700509-166700529 1.0000 20 chr20:19928699-19928719 1.0000 20 chr5:150531634-150531654 1.0000 20 chr3:171065530-171065550 1.0000 20 chr3:46401685-46401705 1.0000 20 chr2:153363601-153363621 1.0000 20 chr10:30876632-30876652 1.0000 20 chr11:76004478-76004498 1.0000 20 chr15:60860797-60860817 1.0000 20 chr6:157042146-157042166 1.0000 20 chr2:169568828-169568848 1.0000 20 chr15:84661512-84661532 1.0000 20 chr8:103119156-103119176 1.0000 20 chr6:139203689-139203709 1.0000 20 chr12:65054588-65054608 1.0000 20 chr3:150478258-150478278 1.0000 20 chr1:206677584-206677604 1.0000 20 chr11:132228610-13222863 1.0000 20 chr1:93443315-93443335 1.0000 20 chr1:42724006-42724026 1.0000 20 chr17:57449789-57449809 1.0000 20 chr3:185972726-185972746 1.0000 20 chr17:16891945-16891965 1.0000 20 chr2:65617445-65617465 1.0000 20 chr11:33409376-33409396 1.0000 20 chr1:33458278-33458298 1.0000 20 chr10:89868065-89868085 1.0000 20 chr9:79056632-79056652 1.0000 20 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/GM12878/inference_raw/MEME/RankLinear0.6_10_IKZF1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/IKZF1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 5000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 5000 norand= no csites= 1000 Letter frequencies in dataset: A 0.265 C 0.237 G 0.233 T 0.265 Background letter frequencies (from file dataset with add-one prior applied): A 0.265 C 0.237 G 0.233 T 0.265 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF CAGRAADT MEME-1 width = 8 sites = 62 llr = 340 E-value = 7.3e-001 ******************************************************************************** -------------------------------------------------------------------------------- Motif CAGRAADT MEME-1 Description -------------------------------------------------------------------------------- Simplified A :7:57522 pos.-specific C a::::21: probability G ::a53242 matrix T :3:::135 bits 2.1 * * 1.9 * * 1.7 * * 1.5 * * Relative 1.3 * * Entropy 1.0 *** * (7.9 bits) 0.8 ***** 0.6 ***** 0.4 ***** 0.2 ******** 0.0 -------- Multilevel CAGGAAGT consensus T AGGTG sequence A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGRAADT MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr3:185255364-185255384 3 1.48e-05 AA CAGGAAGT GTCTTGGGGT chr2:28497947-28497967 6 1.48e-05 GGAGT CAGGAAGT AGGCTTT chr5:142600517-142600537 6 1.48e-05 AAGCT CAGGAAGT CATTTAA chr6:143193130-143193150 9 4.84e-05 ACAGTCCT CAGAAAGT TCTG chr6:112314298-112314318 7 8.44e-05 ACCAAA CAGGAAAT TTGATG chr17:33379051-33379071 12 1.23e-04 atctggaaaa caggaagg t chr1:212392389-212392409 11 1.23e-04 GAAACAGCTC CAGGAGGT TA chr11:7555333-7555353 5 1.23e-04 TATT cagggagt ttgaatgg chr22:40832589-40832609 11 2.46e-04 CAAGAGCCTC CAGAAAGG CT chr17:53514642-53514662 11 2.46e-04 gatccagcca ctggaagt tc chr5:73497524-73497544 2 2.46e-04 T CAGGAGTT GAAGTAGCAA chr7:136044189-136044209 10 2.61e-04 atggagaca caggaaga cca chr11:102216755-10221677 11 3.58e-04 GACTGGCAGG CAGAAATG AC chr16:56979150-56979170 3 3.58e-04 CA CAGGACGT GCTCTTCCTG chr17:56698653-56698673 13 4.36e-04 TTCTGTGGTT CAGGAGAT chr3:34098728-34098748 1 5.20e-04 . ctgaaatt gttgagcaAG chr16:12638112-12638132 10 5.20e-04 ATTGCAACT CAGGACTT TAC chr3:127455201-127455221 9 6.06e-04 AGAGCTTC CAGAAAAG GCAG chr1:160681486-160681506 2 7.57e-04 C CAGGAGTG ACAGAGGCAG chr11:115866905-11586692 8 7.57e-04 GAGGATG CAGAGAGG AAACT chrX:106918023-106918043 9 7.57e-04 ACCCACAG CAGAGAGG GGAG chr5:150531634-150531654 3 1.01e-03 CA CAGAGATg tggatagggg chr15:59665181-59665201 9 1.01e-03 TGGAGCTG CTGGAGTT TCCA chr8:105598113-105598133 12 1.01e-03 GACTAGGAGA CAGAGGTT T chr11:95289646-95289666 11 1.01e-03 TGATGATTAT CAGGATGT CA chr6:88433197-88433217 10 1.01e-03 atgagtcag cagaaaaa gct chr2:7806238-7806258 5 1.01e-03 AGCC CAGAAGTG TGGTTTTC chr6:13230107-13230127 11 1.15e-03 GTGGCAATGG CAGGAACT CT chr1:82014853-82014873 10 1.15e-03 TTTGACATG CTGGAAGA CCT chr1:33458278-33458298 12 1.31e-03 TGGCTGGTCT CAGGGCTT G chr16:10336929-10336949 4 1.50e-03 tca cagaagag gtgggatag chr21:26768789-26768809 13 1.50e-03 CTCATCCACT CAGAGGAT chr1:161676344-161676364 8 1.50e-03 GGATCCT CTGGGAAT AGATT chr6:27599425-27599445 11 1.50e-03 TGGCAGATTT CAGAGAAG GG chr11:9271870-9271890 12 1.66e-03 AAAACATTTC CAGAACTG A chr3:142877627-142877647 5 1.82e-03 TGTC CAGGGCAT GGCTGCTA chr15:64263355-64263375 7 1.82e-03 TGCTCC CTGAAATA AATAAG chr1:93443315-93443335 6 2.03e-03 gtgaa ctggaaaa tgcaggg chr21:30720772-30720792 11 2.03e-03 TCAATAGTAT CTGGAAAA AA chr1:234382717-234382737 7 2.03e-03 ACACGG CAGGGTGT GATGGT chr17:8091195-8091215 3 2.03e-03 TC CTGAACTT ACTGTGTGAA chr1:117312494-117312514 6 2.03e-03 TCTGG CAGGAAGC TCTGAGG chr11:117917490-11791751 8 2.21e-03 TTTGAGT CTGGAGGA CAGAG chr19:39074557-39074577 4 2.21e-03 gca caggagct ctattttcc chr1:12120083-12120103 13 2.21e-03 TTTCCTGGGG CAGAGGGA chr20:62359932-62359952 4 2.21e-03 TTC CTGGGAGA GCTGAGCCC chr8:103119156-103119176 6 2.44e-03 CCCTT CTGAGGTT GGAAAGA chr5:50007322-50007342 13 2.44e-03 attttcattt ctggatgt chr8:42623742-42623762 4 2.67e-03 GAT CAGAGACT GAGGCAGAC chr14:61992175-61992195 3 2.67e-03 AC CAGGATGA GTCACATCCC chr3:50661866-50661886 13 2.67e-03 CTGACAAAGA CTGGGAAG chr2:169568828-169568848 5 2.88e-03 TTCT CAGAACAA ACAGGAAT chr14:51144403-51144423 10 2.88e-03 GGGGAATTT CAGAGTTT TAA chr6:52217345-52217365 2 3.11e-03 C CTGAGGAT TTTATATGAG chr11:126058665-12605868 12 3.11e-03 GAGATGCGGT CAGGATTA T chr2:47212411-47212431 2 3.11e-03 C CTGAAGAG GGGTAGAAAT chr6:137040933-137040953 7 3.28e-03 GATTCA CTGAACTG TGGGAT chr8:82045189-82045209 13 3.28e-03 ccctaagaca ctgagctt chr16:10300142-10300162 8 3.52e-03 CAGCCAG CAGAACCT GCCCA chrX:114851559-114851579 2 3.72e-03 C CAGAGAGC TATCACTGGT chr1:159808712-159808732 11 4.54e-03 catgtggaaa ctgaaatc ca chr11:76004478-76004498 6 5.13e-03 attta cagtaatt tgggatt -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGRAADT MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr3:185255364-185255384 1.5e-05 2_[+1]_10 chr2:28497947-28497967 1.5e-05 5_[+1]_7 chr5:142600517-142600537 1.5e-05 5_[+1]_7 chr6:143193130-143193150 4.8e-05 8_[+1]_4 chr6:112314298-112314318 8.4e-05 6_[+1]_6 chr17:33379051-33379071 0.00012 11_[+1]_1 chr1:212392389-212392409 0.00012 10_[+1]_2 chr11:7555333-7555353 0.00012 4_[+1]_8 chr22:40832589-40832609 0.00025 10_[+1]_2 chr17:53514642-53514662 0.00025 10_[+1]_2 chr5:73497524-73497544 0.00025 1_[+1]_11 chr7:136044189-136044209 0.00026 9_[+1]_3 chr11:102216755-10221677 0.00036 10_[+1]_2 chr16:56979150-56979170 0.00036 2_[+1]_10 chr17:56698653-56698673 0.00044 12_[+1] chr3:34098728-34098748 0.00052 [+1]_12 chr16:12638112-12638132 0.00052 9_[+1]_3 chr3:127455201-127455221 0.00061 8_[+1]_4 chr1:160681486-160681506 0.00076 1_[+1]_11 chr11:115866905-11586692 0.00076 7_[+1]_5 chrX:106918023-106918043 0.00076 8_[+1]_4 chr5:150531634-150531654 0.001 2_[+1]_10 chr15:59665181-59665201 0.001 8_[+1]_4 chr8:105598113-105598133 0.001 11_[+1]_1 chr11:95289646-95289666 0.001 10_[+1]_2 chr6:88433197-88433217 0.001 9_[+1]_3 chr2:7806238-7806258 0.001 4_[+1]_8 chr6:13230107-13230127 0.0012 10_[+1]_2 chr1:82014853-82014873 0.0012 9_[+1]_3 chr1:33458278-33458298 0.0013 11_[+1]_1 chr16:10336929-10336949 0.0015 3_[+1]_9 chr21:26768789-26768809 0.0015 12_[+1] chr1:161676344-161676364 0.0015 7_[+1]_5 chr6:27599425-27599445 0.0015 10_[+1]_2 chr11:9271870-9271890 0.0017 11_[+1]_1 chr3:142877627-142877647 0.0018 4_[+1]_8 chr15:64263355-64263375 0.0018 6_[+1]_6 chr1:93443315-93443335 0.002 5_[+1]_7 chr21:30720772-30720792 0.002 10_[+1]_2 chr1:234382717-234382737 0.002 6_[+1]_6 chr17:8091195-8091215 0.002 2_[+1]_10 chr1:117312494-117312514 0.002 5_[+1]_7 chr11:117917490-11791751 0.0022 7_[+1]_5 chr19:39074557-39074577 0.0022 3_[+1]_9 chr1:12120083-12120103 0.0022 12_[+1] chr20:62359932-62359952 0.0022 3_[+1]_9 chr8:103119156-103119176 0.0024 5_[+1]_7 chr5:50007322-50007342 0.0024 12_[+1] chr8:42623742-42623762 0.0027 3_[+1]_9 chr14:61992175-61992195 0.0027 2_[+1]_10 chr3:50661866-50661886 0.0027 12_[+1] chr2:169568828-169568848 0.0029 4_[+1]_8 chr14:51144403-51144423 0.0029 9_[+1]_3 chr6:52217345-52217365 0.0031 1_[+1]_11 chr11:126058665-12605868 0.0031 11_[+1]_1 chr2:47212411-47212431 0.0031 1_[+1]_11 chr6:137040933-137040953 0.0033 6_[+1]_6 chr8:82045189-82045209 0.0033 12_[+1] chr16:10300142-10300162 0.0035 7_[+1]_5 chrX:114851559-114851579 0.0037 1_[+1]_11 chr1:159808712-159808732 0.0045 10_[+1]_2 chr11:76004478-76004498 0.0051 5_[+1]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGRAADT MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CAGRAADT width=8 seqs=62 chr3:185255364-185255384 ( 3) CAGGAAGT 1 chr2:28497947-28497967 ( 6) CAGGAAGT 1 chr5:142600517-142600537 ( 6) CAGGAAGT 1 chr6:143193130-143193150 ( 9) CAGAAAGT 1 chr6:112314298-112314318 ( 7) CAGGAAAT 1 chr17:33379051-33379071 ( 12) CAGGAAGG 1 chr1:212392389-212392409 ( 11) CAGGAGGT 1 chr11:7555333-7555353 ( 5) CAGGGAGT 1 chr22:40832589-40832609 ( 11) CAGAAAGG 1 chr17:53514642-53514662 ( 11) CTGGAAGT 1 chr5:73497524-73497544 ( 2) CAGGAGTT 1 chr7:136044189-136044209 ( 10) CAGGAAGA 1 chr11:102216755-10221677 ( 11) CAGAAATG 1 chr16:56979150-56979170 ( 3) CAGGACGT 1 chr17:56698653-56698673 ( 13) CAGGAGAT 1 chr3:34098728-34098748 ( 1) CTGAAATT 1 chr16:12638112-12638132 ( 10) CAGGACTT 1 chr3:127455201-127455221 ( 9) CAGAAAAG 1 chr1:160681486-160681506 ( 2) CAGGAGTG 1 chr11:115866905-11586692 ( 8) CAGAGAGG 1 chrX:106918023-106918043 ( 9) CAGAGAGG 1 chr5:150531634-150531654 ( 3) CAGAGATG 1 chr15:59665181-59665201 ( 9) CTGGAGTT 1 chr8:105598113-105598133 ( 12) CAGAGGTT 1 chr11:95289646-95289666 ( 11) CAGGATGT 1 chr6:88433197-88433217 ( 10) CAGAAAAA 1 chr2:7806238-7806258 ( 5) CAGAAGTG 1 chr6:13230107-13230127 ( 11) CAGGAACT 1 chr1:82014853-82014873 ( 10) CTGGAAGA 1 chr1:33458278-33458298 ( 12) CAGGGCTT 1 chr16:10336929-10336949 ( 4) CAGAAGAG 1 chr21:26768789-26768809 ( 13) CAGAGGAT 1 chr1:161676344-161676364 ( 8) CTGGGAAT 1 chr6:27599425-27599445 ( 11) CAGAGAAG 1 chr11:9271870-9271890 ( 12) CAGAACTG 1 chr3:142877627-142877647 ( 5) CAGGGCAT 1 chr15:64263355-64263375 ( 7) CTGAAATA 1 chr1:93443315-93443335 ( 6) CTGGAAAA 1 chr21:30720772-30720792 ( 11) CTGGAAAA 1 chr1:234382717-234382737 ( 7) CAGGGTGT 1 chr17:8091195-8091215 ( 3) CTGAACTT 1 chr1:117312494-117312514 ( 6) CAGGAAGC 1 chr11:117917490-11791751 ( 8) CTGGAGGA 1 chr19:39074557-39074577 ( 4) CAGGAGCT 1 chr1:12120083-12120103 ( 13) CAGAGGGA 1 chr20:62359932-62359952 ( 4) CTGGGAGA 1 chr8:103119156-103119176 ( 6) CTGAGGTT 1 chr5:50007322-50007342 ( 13) CTGGATGT 1 chr8:42623742-42623762 ( 4) CAGAGACT 1 chr14:61992175-61992195 ( 3) CAGGATGA 1 chr3:50661866-50661886 ( 13) CTGGGAAG 1 chr2:169568828-169568848 ( 5) CAGAACAA 1 chr14:51144403-51144423 ( 10) CAGAGTTT 1 chr6:52217345-52217365 ( 2) CTGAGGAT 1 chr11:126058665-12605868 ( 12) CAGGATTA 1 chr2:47212411-47212431 ( 2) CTGAAGAG 1 chr6:137040933-137040953 ( 7) CTGAACTG 1 chr8:82045189-82045209 ( 13) CTGAGCTT 1 chr16:10300142-10300162 ( 8) CAGAACCT 1 chrX:114851559-114851579 ( 2) CAGAGAGC 1 chr1:159808712-159808732 ( 11) CTGAAATC 1 chr11:76004478-76004498 ( 6) CAGTAATT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGRAADT MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 6.99964 E= 7.3e-001 -1260 208 -1260 -1260 139 -1260 -1260 21 -1260 -1260 210 -1260 82 -1260 114 -403 136 -1260 47 -1260 92 -56 5 -145 -13 -188 67 29 -45 -229 5 96 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGRAADT MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 62 E= 7.3e-001 0.000000 1.000000 0.000000 0.000000 0.693548 0.000000 0.000000 0.306452 0.000000 0.000000 1.000000 0.000000 0.467742 0.000000 0.516129 0.016129 0.677419 0.000000 0.322581 0.000000 0.500000 0.161290 0.241935 0.096774 0.241935 0.064516 0.370968 0.322581 0.193548 0.048387 0.241935 0.516129 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CAGRAADT MEME-1 regular expression -------------------------------------------------------------------------------- C[AT]G[GA][AG][AG][GTA][TG] -------------------------------------------------------------------------------- Time 3.30 secs. ******************************************************************************** ******************************************************************************** MOTIF AACCAGCC MEME-2 width = 8 sites = 10 llr = 89 E-value = 1.8e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif AACCAGCC MEME-2 Description -------------------------------------------------------------------------------- Simplified A 97::8::1 pos.-specific C 1:aa::a8 probability G :1:::a:1 matrix T :2::2::: bits 2.1 ** ** 1.9 ** ** 1.7 ** ** 1.5 * ** ** Relative 1.3 * ***** Entropy 1.0 * ****** (12.9 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AACCAGCC consensus T T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AACCAGCC MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr4:152808801-152808821 12 1.37e-05 TTAGGAGTAC AACCAGCC T chr7:83428024-83428044 10 1.37e-05 ggaagctca aaccagcc cat chr22:40895266-40895286 12 1.37e-05 CAAAATAGGG AACCAGCC A chr17:53514642-53514662 2 2.74e-05 g atccagcc actggaagtt chr19:38494334-38494354 5 4.10e-05 GTGG AACCTGCC ATGTGGCG chr5:158832873-158832893 1 5.31e-05 . AGCCAGCC CAGTATTTGA chr18:56209370-56209390 11 7.88e-05 gaggactagc aaccagcg tt chr19:6528921-6528941 3 7.88e-05 AA CACCAGCC AAGGGCTTTC chr6:31705878-31705898 3 9.40e-05 GA AACCAGCA GTTGGTGGTT chr3:185972726-185972746 2 1.08e-04 C ATCCTGCC TCCCACGCAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AACCAGCC MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr4:152808801-152808821 1.4e-05 11_[+2]_1 chr7:83428024-83428044 1.4e-05 9_[+2]_3 chr22:40895266-40895286 1.4e-05 11_[+2]_1 chr17:53514642-53514662 2.7e-05 1_[+2]_11 chr19:38494334-38494354 4.1e-05 4_[+2]_8 chr5:158832873-158832893 5.3e-05 [+2]_12 chr18:56209370-56209390 7.9e-05 10_[+2]_2 chr19:6528921-6528941 7.9e-05 2_[+2]_10 chr6:31705878-31705898 9.4e-05 2_[+2]_10 chr3:185972726-185972746 0.00011 1_[+2]_11 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AACCAGCC MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AACCAGCC width=8 seqs=10 chr4:152808801-152808821 ( 12) AACCAGCC 1 chr7:83428024-83428044 ( 10) AACCAGCC 1 chr22:40895266-40895286 ( 12) AACCAGCC 1 chr17:53514642-53514662 ( 2) ATCCAGCC 1 chr19:38494334-38494354 ( 5) AACCTGCC 1 chr5:158832873-158832893 ( 1) AGCCAGCC 1 chr18:56209370-56209390 ( 11) AACCAGCG 1 chr19:6528921-6528941 ( 3) CACCAGCC 1 chr6:31705878-31705898 ( 3) AACCAGCA 1 chr3:185972726-185972746 ( 2) ATCCTGCC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AACCAGCC MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.5921 E= 1.8e+002 176 -124 -997 -997 140 -997 -122 -40 -997 207 -997 -997 -997 207 -997 -997 159 -997 -997 -40 -997 -997 210 -997 -997 207 -997 -997 -140 175 -122 -997 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AACCAGCC MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 10 E= 1.8e+002 0.900000 0.100000 0.000000 0.000000 0.700000 0.000000 0.100000 0.200000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.200000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.100000 0.800000 0.100000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AACCAGCC MEME-2 regular expression -------------------------------------------------------------------------------- A[AT]CC[AT]GCC -------------------------------------------------------------------------------- Time 4.04 secs. ******************************************************************************** ******************************************************************************** MOTIF CTGTGGTT MEME-3 width = 8 sites = 6 llr = 59 E-value = 6.3e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTGTGGTT MEME-3 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C 7::::::: probability G 2:a:8a:: matrix T 2a:a2:aa bits 2.1 * * 1.9 *** *** 1.7 *** *** 1.5 ******* Relative 1.3 ******* Entropy 1.0 ******* (14.1 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTGTGGTT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGTGGTT MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:56698653-56698673 5 1.48e-05 CTTT CTGTGGTT CAGGAGAT chrX:118816447-118816467 13 1.48e-05 CTGCAGTCAC CTGTGGTT chr4:6944108-6944128 8 1.48e-05 TGAATAG CTGTGGTT TATCT chr22:40297064-40297084 9 2.93e-05 TAGTTCCT GTGTGGTT TGCC chr7:43796472-43796492 9 4.58e-05 cttttctc ttgtggtt tatt chr9:112680929-112680949 5 6.27e-05 ATGA CTGTTGTT AACCCCAT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGTGGTT MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:56698653-56698673 1.5e-05 4_[+3]_8 chrX:118816447-118816467 1.5e-05 12_[+3] chr4:6944108-6944128 1.5e-05 7_[+3]_5 chr22:40297064-40297084 2.9e-05 8_[+3]_4 chr7:43796472-43796492 4.6e-05 8_[+3]_4 chr9:112680929-112680949 6.3e-05 4_[+3]_8 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGTGGTT MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTGTGGTT width=8 seqs=6 chr17:56698653-56698673 ( 5) CTGTGGTT 1 chrX:118816447-118816467 ( 13) CTGTGGTT 1 chr4:6944108-6944128 ( 8) CTGTGGTT 1 chr22:40297064-40297084 ( 9) GTGTGGTT 1 chr7:43796472-43796492 ( 9) TTGTGGTT 1 chr9:112680929-112680949 ( 5) CTGTTGTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGTGGTT MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 9.52677 E= 6.3e+003 -923 149 -48 -67 -923 -923 -923 192 -923 -923 210 -923 -923 -923 -923 192 -923 -923 183 -67 -923 -923 210 -923 -923 -923 -923 192 -923 -923 -923 192 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGTGGTT MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 6 E= 6.3e+003 0.000000 0.666667 0.166667 0.166667 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.833333 0.166667 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTGTGGTT MEME-3 regular expression -------------------------------------------------------------------------------- CTGTGGTT -------------------------------------------------------------------------------- Time 4.78 secs. ******************************************************************************** ******************************************************************************** MOTIF KGCTKSTC MEME-4 width = 8 sites = 19 llr = 142 E-value = 4.5e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif KGCTKSTC MEME-4 Description -------------------------------------------------------------------------------- Simplified A 1::::::: pos.-specific C :3a::5:7 probability G 57::63:3 matrix T 4::a42a: bits 2.1 * 1.9 ** * 1.7 ** * 1.5 ** * Relative 1.3 *** ** Entropy 1.0 **** ** (10.8 bits) 0.8 ***** ** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GGCTGCTC consensus TC TG G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGCTKSTC MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:54758390-54758410 10 3.87e-05 TGAAATCTA GGCTTCTC TGT chr12:111837315-11183733 12 3.87e-05 cacggtggct ggcttctc c chr1:33458278-33458298 3 5.03e-05 CT GGCTGGTC TCAGGGCTTG chr1:247570760-247570780 5 5.03e-05 CTGA GGCTGGTC TTGACCTG chr4:40765457-40765477 9 7.73e-05 TTTCCTCG TGCTTCTC CTAG chr14:55197136-55197156 13 1.04e-04 TTCCTCCTTG GGCTTGTC chr1:150135525-150135545 5 1.16e-04 CCCA GCCTGCTC TAGAGCCA chr12:65019468-65019488 10 1.29e-04 GGCAGACTC TGCTGCTG TCC chr1:59473673-59473693 3 1.42e-04 TG GGCTTCTG CACCAAAGCG chr2:238578424-238578444 12 1.82e-04 AACATGGACC GGCTGTTC C chr9:79056632-79056652 5 1.96e-04 ACAG TCCTGCTC CCATTAAG chr6:26556980-26557000 11 2.09e-04 ACGCATTCCA GCCTTCTC TG chr14:95986174-95986194 9 2.64e-04 TAAAATTA TGCTGTTC GGAA chr1:204548095-204548115 1 2.64e-04 . TGCTGGTG AAACCGAGAG chr2:153363601-153363621 5 2.92e-04 tagt ggcttgtg cggtctct chr15:60843557-60843577 13 3.33e-04 CTTTGGCTCA TCCTGGTC chr4:77119884-77119904 6 4.05e-04 GCTTT TCCTGCTG CTTTCAT chr8:52874917-52874937 13 4.72e-04 agcaacacgc agctgctc chr18:49254302-49254322 3 6.19e-04 CT TGCTTTTG GTAGTGTGCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGCTKSTC MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:54758390-54758410 3.9e-05 9_[+4]_3 chr12:111837315-11183733 3.9e-05 11_[+4]_1 chr1:33458278-33458298 5e-05 2_[+4]_10 chr1:247570760-247570780 5e-05 4_[+4]_8 chr4:40765457-40765477 7.7e-05 8_[+4]_4 chr14:55197136-55197156 0.0001 12_[+4] chr1:150135525-150135545 0.00012 4_[+4]_8 chr12:65019468-65019488 0.00013 9_[+4]_3 chr1:59473673-59473693 0.00014 2_[+4]_10 chr2:238578424-238578444 0.00018 11_[+4]_1 chr9:79056632-79056652 0.0002 4_[+4]_8 chr6:26556980-26557000 0.00021 10_[+4]_2 chr14:95986174-95986194 0.00026 8_[+4]_4 chr1:204548095-204548115 0.00026 [+4]_12 chr2:153363601-153363621 0.00029 4_[+4]_8 chr15:60843557-60843577 0.00033 12_[+4] chr4:77119884-77119904 0.0004 5_[+4]_7 chr8:52874917-52874937 0.00047 12_[+4] chr18:49254302-49254322 0.00062 2_[+4]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGCTKSTC MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF KGCTKSTC width=8 seqs=19 chr12:54758390-54758410 ( 10) GGCTTCTC 1 chr12:111837315-11183733 ( 12) GGCTTCTC 1 chr1:33458278-33458298 ( 3) GGCTGGTC 1 chr1:247570760-247570780 ( 5) GGCTGGTC 1 chr4:40765457-40765477 ( 9) TGCTTCTC 1 chr14:55197136-55197156 ( 13) GGCTTGTC 1 chr1:150135525-150135545 ( 5) GCCTGCTC 1 chr12:65019468-65019488 ( 10) TGCTGCTG 1 chr1:59473673-59473693 ( 3) GGCTTCTG 1 chr2:238578424-238578444 ( 12) GGCTGTTC 1 chr9:79056632-79056652 ( 5) TCCTGCTC 1 chr6:26556980-26557000 ( 11) GCCTTCTC 1 chr14:95986174-95986194 ( 9) TGCTGTTC 1 chr1:204548095-204548115 ( 1) TGCTGGTG 1 chr2:153363601-153363621 ( 5) GGCTTGTG 1 chr15:60843557-60843577 ( 13) TCCTGGTC 1 chr4:77119884-77119904 ( 6) TCCTGCTG 1 chr8:52874917-52874937 ( 13) AGCTGCTC 1 chr18:49254302-49254322 ( 3) TGCTTTTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGCTKSTC MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.85576 E= 4.5e+002 -233 -1089 117 67 -1089 15 166 -1089 -1089 208 -1089 -1089 -1089 -1089 -1089 192 -1089 -1089 131 67 -1089 115 44 -74 -1089 -1089 -1089 192 -1089 153 44 -1089 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGCTKSTC MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 19 E= 4.5e+002 0.052632 0.000000 0.526316 0.421053 0.000000 0.263158 0.736842 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.578947 0.421053 0.000000 0.526316 0.315789 0.157895 0.000000 0.000000 0.000000 1.000000 0.000000 0.684211 0.315789 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif KGCTKSTC MEME-4 regular expression -------------------------------------------------------------------------------- [GT][GC]CT[GT][CG]T[CG] -------------------------------------------------------------------------------- Time 5.58 secs. ******************************************************************************** ******************************************************************************** MOTIF GRGGSAGG MEME-5 width = 8 sites = 2 llr = 20 E-value = 2.2e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif GRGGSAGG MEME-5 Description -------------------------------------------------------------------------------- Simplified A :5:::a:: pos.-specific C ::::5::: probability G a5aa5:aa matrix T :::::::: bits 2.1 * ** ** 1.9 * ** *** 1.7 * ** *** 1.5 * ** *** Relative 1.3 * ** *** Entropy 1.0 ******** (14.5 bits) 0.8 ******** 0.6 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel GAGGCAGG consensus G G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRGGSAGG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr10:89868065-89868085 10 1.99e-05 ttagctgtt gggggagg ggt chr15:60860797-60860817 11 4.26e-05 GCTGCTATGG GAGGCAGG AA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRGGSAGG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr10:89868065-89868085 2e-05 9_[+5]_3 chr15:60860797-60860817 4.3e-05 10_[+5]_2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRGGSAGG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GRGGSAGG width=8 seqs=2 chr10:89868065-89868085 ( 10) GGGGGAGG 1 chr15:60860797-60860817 ( 11) GAGGCAGG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRGGSAGG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 10.6653 E= 2.2e+004 -765 -765 209 -765 91 -765 110 -765 -765 -765 209 -765 -765 -765 209 -765 -765 107 110 -765 191 -765 -765 -765 -765 -765 209 -765 -765 -765 209 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRGGSAGG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 2.2e+004 0.000000 0.000000 1.000000 0.000000 0.500000 0.000000 0.500000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.500000 0.500000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GRGGSAGG MEME-5 regular expression -------------------------------------------------------------------------------- G[AG]GG[CG]AGG -------------------------------------------------------------------------------- Time 6.58 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr2:7806238-7806258 4.35e-04 9_[+3(2.93e-05)]_3 chr18:49254302-49254322 9.85e-02 20 chr6:106593693-106593713 3.75e-01 20 chr9:6133868-6133888 3.56e-01 20 chr2:178412032-178412052 4.12e-01 20 chr12:93830061-93830081 6.25e-01 20 chr2:47212411-47212431 1.09e-01 20 chr14:21093766-21093786 8.21e-02 20 chr12:54635080-54635100 3.52e-01 20 chr3:149294241-149294261 3.10e-01 20 chr1:206890878-206890898 2.96e-01 20 chr1:213155175-213155195 2.45e-01 20 chr1:34996030-34996050 4.99e-01 20 chr1:59479084-59479104 6.97e-01 20 chr2:45060803-45060823 3.02e-02 20 chr20:43275006-43275026 4.68e-01 20 chr4:6944108-6944128 3.62e-03 7_[+3(1.48e-05)]_5 chr2:33719565-33719585 7.29e-02 20 chr1:82014853-82014873 7.36e-02 20 chr1:111177621-111177641 8.04e-01 20 chr6:27599425-27599445 2.72e-01 20 chr1:204548095-204548115 3.30e-02 20 chr12:123205818-12320583 7.59e-01 20 chrX:118816447-118816467 6.39e-04 12_[+3(1.48e-05)] chr14:55197136-55197156 1.15e-02 20 chr22:40895266-40895286 2.67e-02 11_[+2(1.37e-05)]_1 chr18:42380184-42380204 9.22e-01 20 chr1:85461725-85461745 6.00e-01 20 chr2:20776703-20776723 9.94e-01 20 chr6:112314298-112314318 4.53e-02 6_[+1(8.44e-05)]_6 chr13:103831784-10383180 9.18e-01 20 chr20:10434097-10434117 2.13e-01 20 chr7:50304722-50304742 9.63e-01 20 chr10:92180629-92180649 2.49e-01 20 chr1:159808712-159808732 2.47e-01 20 chr3:121810505-121810525 7.47e-01 20 chr6:128921738-128921758 2.82e-01 20 chr5:111482211-111482231 6.15e-01 20 chr6:28510743-28510763 4.02e-01 20 chr5:50007322-50007342 1.01e-01 20 chr1:45142425-45142445 8.02e-01 20 chr19:17447761-17447781 7.60e-01 20 chr20:62359932-62359952 9.82e-02 20 chr7:142531297-142531317 5.03e-02 20 chr6:26556980-26557000 2.03e-02 20 chr5:142600517-142600537 1.97e-02 5_[+1(1.48e-05)]_7 chr12:125424776-12542479 1.64e-03 20 chr5:112265520-112265540 4.32e-01 20 chr16:10300142-10300162 2.82e-03 10_[+2(4.10e-05)]_2 chr2:161080699-161080719 4.53e-01 20 chr8:82045189-82045209 2.36e-01 20 chr6:31705878-31705898 1.86e-04 2_[+2(9.40e-05)]_10 chr6:16636500-16636520 9.48e-01 20 chr10:125919599-12591961 8.08e-01 20 chr17:44217132-44217152 4.09e-01 20 chr1:12120083-12120103 3.80e-03 20 chr11:7555333-7555353 1.30e-02 20 chr7:37805688-37805708 9.62e-01 20 chr14:95986174-95986194 6.04e-02 20 chr16:10965473-10965493 4.38e-01 20 chr6:16471302-16471322 5.27e-01 20 chr5:88649731-88649751 1.05e-01 20 chr1:117312494-117312514 4.60e-02 20 chr1:172307709-172307729 9.25e-01 20 chr11:126058665-12605868 8.44e-02 20 chr16:15993591-15993611 9.14e-01 20 chr1:207140970-207140990 8.57e-01 20 chr14:53576043-53576063 5.71e-01 20 chr4:79578399-79578419 8.18e-01 20 chr6:10532049-10532069 1.16e-01 20 chr15:64263355-64263375 5.17e-01 20 chr8:126660635-126660655 2.16e-01 20 chr6:88433197-88433217 3.80e-02 20 chr8:102920627-102920647 9.99e-01 20 chrX:13031921-13031941 5.61e-01 20 chr3:46340998-46341018 9.69e-01 20 chr13:41163917-41163937 1.22e-01 20 chr1:212392389-212392409 4.87e-03 20 chr11:9271870-9271890 3.39e-01 20 chrX:106918023-106918043 8.29e-02 20 chr5:73497524-73497544 2.39e-02 20 chr7:43796472-43796492 3.60e-02 8_[+3(4.58e-05)]_4 chr2:17996853-17996873 3.39e-01 20 chr3:127455201-127455221 1.70e-01 20 chr14:68751779-68751799 5.36e-02 20 chr5:171606709-171606729 8.16e-01 20 chr1:247570760-247570780 6.46e-05 4_[+4(5.03e-05)]_8 chr17:8091195-8091215 2.27e-01 20 chr20:52228301-52228321 4.07e-02 20 chr4:152803790-152803810 3.40e-01 20 chr2:58266505-58266525 9.00e-01 20 chr1:109709954-109709974 4.08e-01 20 chr1:9097640-9097660 5.79e-01 20 chr8:141519400-141519420 8.92e-01 20 chr2:202845294-202845314 9.93e-01 20 chr4:77119884-77119904 6.10e-02 20 chr18:10928181-10928201 1.51e-01 20 chr12:108729666-10872968 7.73e-01 20 chr1:183871276-183871296 6.45e-01 20 chr1:245108671-245108691 3.14e-02 20 chr11:95289646-95289666 1.78e-01 20 chr8:8483387-8483407 6.43e-02 20 chr6:100619997-100620017 4.89e-01 20 chr17:33379051-33379071 9.89e-03 20 chr8:119971336-119971356 1.95e-01 20 chr9:27489232-27489252 5.89e-01 20 chr5:55391625-55391645 8.90e-01 20 chr11:77160198-77160218 6.61e-01 20 chr18:56209134-56209154 2.14e-01 20 chr15:64283981-64284001 6.07e-01 20 chr20:1516576-1516596 2.83e-01 20 chr4:40765457-40765477 2.98e-02 8_[+4(7.73e-05)]_4 chr19:6528921-6528941 3.08e-02 2_[+2(7.88e-05)]_10 chr12:116632812-11663283 9.02e-01 20 chr13:41634718-41634738 4.86e-01 20 chr17:62159634-62159654 5.18e-01 20 chr8:105290916-105290936 8.45e-01 20 chr1:234980347-234980367 6.40e-01 20 chr11:7542459-7542479 3.15e-01 20 chr1:32423552-32423572 5.50e-01 20 chr8:105598113-105598133 1.86e-02 20 chrX:114851559-114851579 1.58e-01 20 chr1:59473673-59473693 4.07e-02 20 chr17:46560924-46560944 3.65e-01 20 chr4:40625235-40625255 1.02e-01 20 chr11:115866905-11586692 4.44e-02 20 chr19:38494334-38494354 6.02e-03 4_[+2(4.10e-05)]_8 chr22:31102029-31102049 1.20e-01 20 chr6:149401110-149401130 4.36e-01 20 chr6:52217345-52217365 1.30e-01 20 chr15:89710639-89710659 7.85e-01 20 chr17:53514642-53514662 3.27e-04 1_[+2(2.74e-05)]_11 chr16:12638112-12638132 1.05e-01 20 chr18:56209370-56209390 7.64e-02 10_[+2(7.88e-05)]_2 chr15:60843557-60843577 2.71e-02 20 chr2:28497947-28497967 1.10e-03 5_[+1(1.48e-05)]_7 chr1:42421354-42421374 7.82e-01 20 chr20:52517156-52517176 4.62e-01 20 chr7:83428024-83428044 1.80e-02 9_[+2(1.37e-05)]_3 chr3:143388327-143388347 9.35e-02 20 chr19:39074557-39074577 3.04e-01 20 chr4:152808801-152808821 2.35e-02 11_[+2(1.37e-05)]_1 chr2:231818700-231818720 6.36e-03 20 chr6:13230107-13230127 8.30e-02 20 chr7:136044189-136044209 8.20e-02 20 chr1:12494317-12494337 7.52e-01 20 chr1:213102023-213102043 9.60e-01 20 chr3:196254744-196254764 3.96e-02 20 chr1:161676344-161676364 9.40e-02 20 chr3:142877627-142877647 5.06e-03 20 chr16:87814432-87814452 6.13e-01 20 chr6:88435156-88435176 7.85e-01 20 chr3:119114922-119114942 9.84e-01 20 chr12:111837315-11183733 4.10e-04 11_[+4(3.87e-05)]_1 chr20:35994919-35994939 9.83e-01 20 chr7:2446635-2446655 9.68e-01 20 chr5:158832873-158832893 7.80e-03 [+2(5.31e-05)]_12 chr11:75584513-75584533 3.61e-01 20 chr1:42421553-42421573 6.17e-01 20 chr14:65647193-65647213 8.40e-01 20 chr16:56979150-56979170 1.60e-02 20 chr17:16878850-16878870 5.41e-01 20 chr21:26768789-26768809 1.10e-01 20 chr11:128283174-12828319 2.89e-01 20 chr11:117917490-11791751 6.66e-02 20 chr2:218083670-218083690 3.86e-01 20 chr3:121952557-121952577 8.67e-01 20 chr4:185342377-185342397 9.78e-01 20 chr20:47406823-47406843 9.26e-01 20 chr10:104405704-10440572 3.89e-01 20 chr1:234382717-234382737 1.72e-02 20 chrX:29574183-29574203 4.63e-01 20 chr6:53104483-53104503 9.94e-01 20 chr15:59665181-59665201 1.02e-03 20 chr17:40808175-40808195 2.19e-01 20 chr6:143193130-143193150 7.73e-02 8_[+1(4.84e-05)]_4 chr9:129916847-129916867 5.45e-01 20 chr22:40832589-40832609 1.87e-02 20 chr20:48955482-48955502 2.29e-01 20 chr12:112621255-11262127 9.86e-01 20 chr9:112680929-112680949 2.45e-02 4_[+3(6.27e-05)]_8 chr6:119765947-119765967 7.35e-01 20 chr3:185255364-185255384 6.57e-03 2_[+1(1.48e-05)]_10 chr16:10336929-10336949 7.85e-02 20 chr1:160681486-160681506 3.80e-02 20 chr3:50661866-50661886 2.73e-01 20 chr16:29674182-29674202 2.46e-01 20 chr8:61816559-61816579 7.37e-01 20 chr1:172327768-172327788 1.39e-01 20 chr1:236047137-236047157 4.70e-01 20 chr10:98047149-98047169 8.89e-01 20 chr21:30720772-30720792 4.27e-01 20 chr19:6556613-6556633 3.78e-01 20 chr11:72865477-72865497 1.96e-01 20 chr21:19157117-19157137 9.89e-01 20 chr14:51144403-51144423 1.86e-01 20 chr10:125312831-12531285 1.90e-01 20 chr12:92757695-92757715 3.53e-01 20 chr17:56698653-56698673 1.51e-04 4_[+3(1.48e-05)]_8 chr19:4369345-4369365 9.47e-02 20 chr2:45918423-45918443 3.97e-03 20 chr11:102216755-10221677 2.47e-02 20 chr2:37828148-37828168 7.42e-01 20 chrX:13002988-13003008 3.97e-01 20 chr1:150135525-150135545 1.42e-02 20 chr11:123135316-12313533 4.07e-01 20 chr6:137040933-137040953 1.68e-01 20 chr15:66194918-66194938 8.18e-01 20 chr3:34098728-34098748 2.45e-02 20 chr5:88638432-88638452 4.35e-01 20 chr9:5459452-5459472 2.56e-01 20 chr10:11289143-11289163 3.14e-01 20 chr12:54758390-54758410 9.63e-03 9_[+4(3.87e-05)]_3 chr2:238578424-238578444 1.75e-02 20 chr1:182592391-182592411 4.08e-02 20 chr17:43380286-43380306 1.34e-01 20 chr22:40297064-40297084 4.71e-03 8_[+3(2.93e-05)]_4 chr12:65019468-65019488 2.11e-02 20 chr14:61992175-61992195 3.54e-01 20 chr6:135329725-135329745 5.59e-01 20 chr8:42623742-42623762 1.47e-02 20 chr8:52874917-52874937 9.00e-02 20 chr6:166700509-166700529 3.16e-01 20 chr20:19928699-19928719 3.73e-01 20 chr5:150531634-150531654 3.43e-02 20 chr3:171065530-171065550 7.71e-01 20 chr3:46401685-46401705 9.23e-02 20 chr2:153363601-153363621 1.44e-02 20 chr10:30876632-30876652 2.82e-01 20 chr11:76004478-76004498 3.84e-01 20 chr15:60860797-60860817 1.09e-02 10_[+5(4.26e-05)]_2 chr6:157042146-157042166 7.21e-01 20 chr2:169568828-169568848 3.62e-01 20 chr15:84661512-84661532 9.99e-01 20 chr8:103119156-103119176 4.42e-04 20 chr6:139203689-139203709 5.57e-01 20 chr12:65054588-65054608 5.10e-01 20 chr3:150478258-150478278 1.62e-01 20 chr1:206677584-206677604 8.93e-01 20 chr11:132228610-13222863 2.17e-02 20 chr1:93443315-93443335 1.58e-01 20 chr1:42724006-42724026 8.63e-01 20 chr17:57449789-57449809 4.93e-01 20 chr3:185972726-185972746 1.00e-01 20 chr17:16891945-16891965 5.51e-01 20 chr2:65617445-65617465 8.97e-01 20 chr11:33409376-33409396 2.68e-01 20 chr1:33458278-33458298 1.15e-03 2_[+4(5.03e-05)]_10 chr10:89868065-89868085 5.61e-04 9_[+5(1.99e-05)]_3 chr9:79056632-79056652 7.72e-02 20 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n04.farnam.hpc.yale.internal ********************************************************************************