******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/FOS.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr19:40728068-40728088 1.0000 20 chr19:46148936-46148956 1.0000 20 chr19:4471717-4471737 1.0000 20 chr17:80455127-80455147 1.0000 20 chr7:75947451-75947471 1.0000 20 chrX:47221685-47221705 1.0000 20 chrX:47415621-47415641 1.0000 20 chr19:1041126-1041146 1.0000 20 chr19:2841383-2841403 1.0000 20 chr16:4852973-4852993 1.0000 20 chr5:179719090-179719110 1.0000 20 chr5:32313341-32313361 1.0000 20 chr1:10270473-10270493 1.0000 20 chr9:80911951-80911971 1.0000 20 chr15:69113316-69113336 1.0000 20 chr11:560871-560891 1.0000 20 chr17:47866566-47866586 1.0000 20 chr11:17298189-17298209 1.0000 20 chr3:100211369-100211389 1.0000 20 chr20:56004973-56004993 1.0000 20 chr19:19249330-19249350 1.0000 20 chr13:107188077-10718809 1.0000 20 chr19:2945026-2945046 1.0000 20 chr20:17663022-17663042 1.0000 20 chr19:37288257-37288277 1.0000 20 chr19:4342899-4342919 1.0000 20 chr22:20004448-20004468 1.0000 20 chr19:18654422-18654442 1.0000 20 chr13:50159705-50159725 1.0000 20 chr1:25757263-25757283 1.0000 20 chr2:71454292-71454312 1.0000 20 chr6:80247202-80247222 1.0000 20 chr1:54204947-54204967 1.0000 20 chr11:34379633-34379653 1.0000 20 chr13:26796027-26796047 1.0000 20 chr3:114866196-114866216 1.0000 20 chrX:1780640-1780660 1.0000 20 chr13:30969742-30969762 1.0000 20 chr13:20532768-20532788 1.0000 20 chr11:13299095-13299115 1.0000 20 chr16:87351049-87351069 1.0000 20 chr17:44302795-44302815 1.0000 20 chr16:2955853-2955873 1.0000 20 chr4:175204409-175204429 1.0000 20 chr11:4629550-4629570 1.0000 20 chr19:13906104-13906124 1.0000 20 chr3:149530944-149530964 1.0000 20 chr6:158653181-158653201 1.0000 20 chr16:16002075-16002095 1.0000 20 chr1:167691157-167691177 1.0000 20 chr11:134093925-13409394 1.0000 20 chr6:122720626-122720646 1.0000 20 chr5:89705635-89705655 1.0000 20 chr21:45175118-45175138 1.0000 20 chr1:232765971-232765991 1.0000 20 chr10:101190507-10119052 1.0000 20 chr3:50605211-50605231 1.0000 20 chr12:6960521-6960541 1.0000 20 chr19:1133745-1133765 1.0000 20 chrX:48958228-48958248 1.0000 20 chr20:40247103-40247123 1.0000 20 chr22:20067703-20067723 1.0000 20 chr16:58663850-58663870 1.0000 20 chr1:28562522-28562542 1.0000 20 chr12:14927216-14927236 1.0000 20 chr12:53473239-53473259 1.0000 20 chr9:135905977-135905997 1.0000 20 chr19:8478118-8478138 1.0000 20 chr12:109535809-10953582 1.0000 20 chr2:65283399-65283419 1.0000 20 chr19:6372650-6372670 1.0000 20 chr12:112451178-11245119 1.0000 20 chr16:57570007-57570027 1.0000 20 chr22:42342827-42342847 1.0000 20 chr19:42580192-42580212 1.0000 20 chr19:41082713-41082733 1.0000 20 chr14:74960331-74960351 1.0000 20 chr1:227127827-227127847 1.0000 20 chr6:153304256-153304276 1.0000 20 chr8:145159286-145159306 1.0000 20 chr19:21105984-21106004 1.0000 20 chr13:73633035-73633055 1.0000 20 chr3:185826978-185826998 1.0000 20 chr22:35696178-35696198 1.0000 20 chr1:150602221-150602241 1.0000 20 chr11:6640663-6640683 1.0000 20 chr19:54641317-54641337 1.0000 20 chr19:17420260-17420280 1.0000 20 chr16:2264957-2264977 1.0000 20 chr12:121342215-12134223 1.0000 20 chr14:78083238-78083258 1.0000 20 chr2:46771320-46771340 1.0000 20 chr3:152879093-152879113 1.0000 20 chr13:29293185-29293205 1.0000 20 chr19:21541723-21541743 1.0000 20 chr14:23755466-23755486 1.0000 20 chr11:66725908-66725928 1.0000 20 chr1:155211067-155211087 1.0000 20 chr16:46723507-46723527 1.0000 20 chr17:80416459-80416479 1.0000 20 chr8:25316036-25316056 1.0000 20 chr4:775677-775697 1.0000 20 chr17:41978050-41978070 1.0000 20 chr8:144450906-144450926 1.0000 20 chr22:40440249-40440269 1.0000 20 chr16:1876867-1876887 1.0000 20 chr16:30621765-30621785 1.0000 20 chr1:85527930-85527950 1.0000 20 chr19:20959040-20959060 1.0000 20 chr15:83478282-83478302 1.0000 20 chr15:90895413-90895433 1.0000 20 chr17:46688412-46688432 1.0000 20 chr2:232646051-232646071 1.0000 20 chrX:154444609-154444629 1.0000 20 chrX:47420527-47420547 1.0000 20 chr10:46168278-46168298 1.0000 20 chr19:46498639-46498659 1.0000 20 chr17:43138946-43138966 1.0000 20 chr5:145583063-145583083 1.0000 20 chr19:40931803-40931823 1.0000 20 chr17:2952393-2952413 1.0000 20 chr7:23053807-23053827 1.0000 20 chr14:54863601-54863621 1.0000 20 chr4:166248743-166248763 1.0000 20 chr11:71814513-71814533 1.0000 20 chr17:74667934-74667954 1.0000 20 chrX:101975611-101975631 1.0000 20 chr19:37808623-37808643 1.0000 20 chr19:3035709-3035729 1.0000 20 chr1:150601703-150601723 1.0000 20 chr20:44441141-44441161 1.0000 20 chr3:131100570-131100590 1.0000 20 chr19:15947945-15947965 1.0000 20 chr1:173446184-173446204 1.0000 20 chr5:43313854-43313874 1.0000 20 chr22:37172268-37172288 1.0000 20 chr17:79196853-79196873 1.0000 20 chr7:48075031-48075051 1.0000 20 chr19:33166143-33166163 1.0000 20 chr11:107798923-10779894 1.0000 20 chr11:62495441-62495461 1.0000 20 chr11:68228085-68228105 1.0000 20 chr15:90118606-90118626 1.0000 20 chr4:89513541-89513561 1.0000 20 chr2:73460487-73460507 1.0000 20 chr15:43213085-43213105 1.0000 20 chr17:8534271-8534291 1.0000 20 chr15:64673769-64673789 1.0000 20 chr19:36193369-36193389 1.0000 20 chr22:37582486-37582506 1.0000 20 chr17:17184085-17184105 1.0000 20 chr18:14132517-14132537 1.0000 20 chr9:133588157-133588177 1.0000 20 chr14:73393105-73393125 1.0000 20 chr19:3344307-3344327 1.0000 20 chr12:123868604-12386862 1.0000 20 chr1:6845327-6845347 1.0000 20 chr3:148804366-148804386 1.0000 20 chr6:160183435-160183455 1.0000 20 chr12:56211742-56211762 1.0000 20 chr12:125534246-12553426 1.0000 20 chr22:38054414-38054434 1.0000 20 chr8:11660040-11660060 1.0000 20 chr19:54640807-54640827 1.0000 20 chr13:20207734-20207754 1.0000 20 chr2:73298521-73298541 1.0000 20 chrX:49125650-49125670 1.0000 20 chr19:58790204-58790224 1.0000 20 chrX:102941744-102941764 1.0000 20 chr19:18315143-18315163 1.0000 20 chr6:31126228-31126248 1.0000 20 chr15:86338208-86338228 1.0000 20 chr19:14228701-14228721 1.0000 20 chr6:27862264-27862284 1.0000 20 chr17:38574288-38574308 1.0000 20 chr2:85822783-85822803 1.0000 20 chr12:49259713-49259733 1.0000 20 chr14:102991137-10299115 1.0000 20 chr12:51420191-51420211 1.0000 20 chr10:99052451-99052471 1.0000 20 chr12:113658981-11365900 1.0000 20 chr16:90143799-90143819 1.0000 20 chr1:38397550-38397570 1.0000 20 chr6:32146055-32146075 1.0000 20 chr15:44487574-44487594 1.0000 20 chr16:67217593-67217613 1.0000 20 chr11:124981570-12498159 1.0000 20 chr19:17377996-17378016 1.0000 20 chr14:58765088-58765108 1.0000 20 chr9:34989599-34989619 1.0000 20 chr9:139844594-139844614 1.0000 20 chr6:33422260-33422280 1.0000 20 chr7:150076329-150076349 1.0000 20 chr19:1507868-1507888 1.0000 20 chr21:44772639-44772659 1.0000 20 chr9:86595190-86595210 1.0000 20 chr13:41240839-41240859 1.0000 20 chr1:153895589-153895609 1.0000 20 chr3:126423017-126423037 1.0000 20 chr14:94492634-94492654 1.0000 20 chr2:10262763-10262783 1.0000 20 chr6:82957518-82957538 1.0000 20 chr9:139780779-139780799 1.0000 20 chr22:21996449-21996469 1.0000 20 chr17:48944872-48944892 1.0000 20 chr19:7894880-7894900 1.0000 20 chr14:74551241-74551261 1.0000 20 chr11:58874577-58874597 1.0000 20 chr19:19174697-19174717 1.0000 20 chr6:27806243-27806263 1.0000 20 chr3:93698901-93698921 1.0000 20 chr17:80656643-80656663 1.0000 20 chr2:159313321-159313341 1.0000 20 chr16:3054062-3054082 1.0000 20 chr9:131843281-131843301 1.0000 20 chr16:22386034-22386054 1.0000 20 chr11:67275765-67275785 1.0000 20 chr5:98109236-98109256 1.0000 20 chr1:112282090-112282110 1.0000 20 chr1:15930163-15930183 1.0000 20 chr12:122028229-12202824 1.0000 20 chr3:52091417-52091437 1.0000 20 chr17:73452640-73452660 1.0000 20 chr19:8408206-8408226 1.0000 20 chr4:6271467-6271487 1.0000 20 chr1:43312175-43312195 1.0000 20 chr16:70323496-70323516 1.0000 20 chr9:37465761-37465781 1.0000 20 chr6:159527947-159527967 1.0000 20 chr19:45873925-45873945 1.0000 20 chr10:102790934-10279095 1.0000 20 chr17:16945646-16945666 1.0000 20 chr3:39425831-39425851 1.0000 20 chr19:18133125-18133145 1.0000 20 chr4:468013-468033 1.0000 20 chr16:31724510-31724530 1.0000 20 chr19:4472104-4472124 1.0000 20 chr15:77223953-77223973 1.0000 20 chr1:41174925-41174945 1.0000 20 chr13:20437871-20437891 1.0000 20 chr17:47270342-47270362 1.0000 20 chr1:39325543-39325563 1.0000 20 chr16:27386603-27386623 1.0000 20 chr7:100184173-100184193 1.0000 20 chr1:109940653-109940673 1.0000 20 chr19:49224053-49224073 1.0000 20 chr16:1525062-1525082 1.0000 20 chr16:88923500-88923520 1.0000 20 chr19:41284022-41284042 1.0000 20 chr6:27100701-27100721 1.0000 20 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/GM12878/inference_raw/MEME/RankLinear0.6_10_FOS/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/FOS.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 5000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 5000 norand= no csites= 1000 Letter frequencies in dataset: A 0.206 C 0.298 G 0.302 T 0.193 Background letter frequencies (from file dataset with add-one prior applied): A 0.206 C 0.298 G 0.302 T 0.193 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF YRRCCAAT MEME-1 width = 8 sites = 52 llr = 369 E-value = 4.1e-032 ******************************************************************************** -------------------------------------------------------------------------------- Motif YRRCCAAT MEME-1 Description -------------------------------------------------------------------------------- Simplified A 133::9a1 pos.-specific C 421aa::: probability G 256::::: matrix T 3:1::1:9 bits 2.4 2.1 ** 1.9 *** 1.7 * *** Relative 1.4 ***** Entropy 1.2 ***** (10.2 bits) 0.9 ***** 0.7 ***** 0.5 ****** 0.2 ******** 0.0 -------- Multilevel CGGCCAAT consensus TAA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YRRCCAAT MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:43312175-43312195 13 5.48e-05 GCAGTCATGG TAGCCAAT chr2:10262763-10262783 7 5.48e-05 ATGGCA CAGCCAAT GGGAAG chr3:126423017-126423037 13 5.48e-05 CCTCTGGCGT CGGCCAAT chr13:41240839-41240859 1 5.48e-05 . CGGCCAAT GGGCATGCGG chr19:3035709-3035729 6 5.48e-05 GAAAC TGGCCAAT GGGGATT chr3:152879093-152879113 13 5.48e-05 GCCTTGGCGG CAGCCAAT chr19:17420260-17420280 6 5.48e-05 GGATG CGGCCAAT GGAAGCG chr15:69113316-69113336 6 5.48e-05 GGCAA CAGCCAAT GGCAGTG chr19:4471717-4471737 7 5.48e-05 TTGTGA TGGCCAAT GCCTGC chr6:159527947-159527967 12 9.22e-05 tcatagcggg taaccaat t chr9:37465761-37465781 8 9.22e-05 TTCGCTG CAACCAAT CAAAA chr17:73452640-73452660 9 9.22e-05 TCAAATCC TGACCAAT CGGT chr5:98109236-98109256 11 9.22e-05 CGTGCGGTCA CAACCAAT GG chr1:6845327-6845347 2 9.22e-05 T TGACCAAT CCTTTCAGTC chr5:43313854-43313874 12 9.22e-05 AGAGGTTCTC CGACCAAT T chr13:26796027-26796047 13 9.22e-05 AGAAGGCAGT TAACCAAT chr5:32313341-32313361 1 9.22e-05 . CAACCAAT CCAGAGAGCG chr5:179719090-179719110 9 9.22e-05 CCTCGCGC CGACCAAT CAGC chr2:73298521-73298541 2 1.26e-04 A GGGCCAAT AGGAAGCCAA chr4:775677-775697 10 1.26e-04 AGCCTCTAG GAGCCAAT CAT chr16:16002075-16002095 12 1.26e-04 acactcagaa gggccaat g chr17:47270342-47270362 5 1.81e-04 TGAG CCGCCAAT GAAGTGGC chr3:52091417-52091437 1 1.81e-04 . GGACCAAT CAACTTCCGC chr19:19174697-19174717 11 1.81e-04 TGCTTCATAC TCGCCAAT CA chr16:90143799-90143819 8 1.81e-04 GGCGAGC CCGCCAAT CGGCA chr9:80911951-80911971 4 1.81e-04 CGC GAACCAAT TAGCGCAGG chr7:100184173-100184193 4 2.04e-04 AGA AGGCCAAT TAGAGCCTC chr14:58765088-58765108 5 2.04e-04 GAAA AAGCCAAT CATAAGTG chr19:41284022-41284042 12 2.26e-04 CCTTCTCACG CCACCAAT C chr9:139844594-139844614 13 2.26e-04 TGCCCACCCT CCACCAAT chr17:38574288-38574308 13 2.42e-04 TTGTTTGAAT AAACCAAT chr16:2955853-2955873 9 2.42e-04 GCGTGGCT AGACCAAT GGGC chr19:20959040-20959060 10 2.96e-04 GCTGGAAAC CGTCCAAT CAG chr19:21541723-21541743 8 2.96e-04 TGGGAAC TGTCCAAT CAGGC chr12:49259713-49259733 13 3.50e-04 GACTCTGTTA CGCCCAAT chr16:58663850-58663870 11 3.50e-04 CTGTGGCTTC TACCCAAT CA chr6:153304256-153304276 11 3.64e-04 TTGCATGCGC GCACCAAT AG chr3:114866196-114866216 1 3.77e-04 . ACGCCAAT CTTGGCTTCA chr19:3344307-3344327 13 5.14e-04 CCTTGCTGTG TGGCCTAT chr22:37582486-37582506 7 5.14e-04 GTAGAC CTGCCAAT CAGATG chr7:23053807-23053827 2 5.14e-04 T CAGCCTAT CGCCGTCCTC chr19:41082713-41082733 12 5.14e-04 TGGAGTCTCT GGCCCAAT G chr19:17377996-17378016 12 6.28e-04 TAGTCTGATT CGGCCAAA A chr19:37808623-37808643 1 6.28e-04 . TGGCTAAT GTGGAGCGAA chr19:46498639-46498659 1 6.28e-04 . TGGCTAAT GGAAACTTGG chr10:46168278-46168298 12 6.28e-04 CTTTCGCTGC CCTCCAAT C chr22:20067703-20067723 5 7.24e-04 GGCT CCCCCAAT gcggggcg chr6:32146055-32146075 5 8.62e-04 CCAA TAGCCATT GTGCGAAG chr19:14228701-14228721 8 8.62e-04 GGACTCT CGGCCATT CACTC chr14:102991137-10299115 6 9.41e-04 gaggg gagcctat ccatagg chr12:6960521-6960541 13 1.01e-03 GACCCGCCTC GAGCCAAA chr2:71454292-71454312 5 1.01e-03 TATT GGGCCAAA GAAGATGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YRRCCAAT MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:43312175-43312195 5.5e-05 12_[+1] chr2:10262763-10262783 5.5e-05 6_[+1]_6 chr3:126423017-126423037 5.5e-05 12_[+1] chr13:41240839-41240859 5.5e-05 [+1]_12 chr19:3035709-3035729 5.5e-05 5_[+1]_7 chr3:152879093-152879113 5.5e-05 12_[+1] chr19:17420260-17420280 5.5e-05 5_[+1]_7 chr15:69113316-69113336 5.5e-05 5_[+1]_7 chr19:4471717-4471737 5.5e-05 6_[+1]_6 chr6:159527947-159527967 9.2e-05 11_[+1]_1 chr9:37465761-37465781 9.2e-05 7_[+1]_5 chr17:73452640-73452660 9.2e-05 8_[+1]_4 chr5:98109236-98109256 9.2e-05 10_[+1]_2 chr1:6845327-6845347 9.2e-05 1_[+1]_11 chr5:43313854-43313874 9.2e-05 11_[+1]_1 chr13:26796027-26796047 9.2e-05 12_[+1] chr5:32313341-32313361 9.2e-05 [+1]_12 chr5:179719090-179719110 9.2e-05 8_[+1]_4 chr2:73298521-73298541 0.00013 1_[+1]_11 chr4:775677-775697 0.00013 9_[+1]_3 chr16:16002075-16002095 0.00013 11_[+1]_1 chr17:47270342-47270362 0.00018 4_[+1]_8 chr3:52091417-52091437 0.00018 [+1]_12 chr19:19174697-19174717 0.00018 10_[+1]_2 chr16:90143799-90143819 0.00018 7_[+1]_5 chr9:80911951-80911971 0.00018 3_[+1]_9 chr7:100184173-100184193 0.0002 3_[+1]_9 chr14:58765088-58765108 0.0002 4_[+1]_8 chr19:41284022-41284042 0.00023 11_[+1]_1 chr9:139844594-139844614 0.00023 12_[+1] chr17:38574288-38574308 0.00024 12_[+1] chr16:2955853-2955873 0.00024 8_[+1]_4 chr19:20959040-20959060 0.0003 9_[+1]_3 chr19:21541723-21541743 0.0003 7_[+1]_5 chr12:49259713-49259733 0.00035 12_[+1] chr16:58663850-58663870 0.00035 10_[+1]_2 chr6:153304256-153304276 0.00036 10_[+1]_2 chr3:114866196-114866216 0.00038 [+1]_12 chr19:3344307-3344327 0.00051 12_[+1] chr22:37582486-37582506 0.00051 6_[+1]_6 chr7:23053807-23053827 0.00051 1_[+1]_11 chr19:41082713-41082733 0.00051 11_[+1]_1 chr19:17377996-17378016 0.00063 11_[+1]_1 chr19:37808623-37808643 0.00063 [+1]_12 chr19:46498639-46498659 0.00063 [+1]_12 chr10:46168278-46168298 0.00063 11_[+1]_1 chr22:20067703-20067723 0.00072 4_[+1]_8 chr6:32146055-32146075 0.00086 4_[+1]_8 chr19:14228701-14228721 0.00086 7_[+1]_5 chr14:102991137-10299115 0.00094 5_[+1]_7 chr12:6960521-6960541 0.001 12_[+1] chr2:71454292-71454312 0.001 4_[+1]_8 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YRRCCAAT MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF YRRCCAAT width=8 seqs=52 chr1:43312175-43312195 ( 13) TAGCCAAT 1 chr2:10262763-10262783 ( 7) CAGCCAAT 1 chr3:126423017-126423037 ( 13) CGGCCAAT 1 chr13:41240839-41240859 ( 1) CGGCCAAT 1 chr19:3035709-3035729 ( 6) TGGCCAAT 1 chr3:152879093-152879113 ( 13) CAGCCAAT 1 chr19:17420260-17420280 ( 6) CGGCCAAT 1 chr15:69113316-69113336 ( 6) CAGCCAAT 1 chr19:4471717-4471737 ( 7) TGGCCAAT 1 chr6:159527947-159527967 ( 12) TAACCAAT 1 chr9:37465761-37465781 ( 8) CAACCAAT 1 chr17:73452640-73452660 ( 9) TGACCAAT 1 chr5:98109236-98109256 ( 11) CAACCAAT 1 chr1:6845327-6845347 ( 2) TGACCAAT 1 chr5:43313854-43313874 ( 12) CGACCAAT 1 chr13:26796027-26796047 ( 13) TAACCAAT 1 chr5:32313341-32313361 ( 1) CAACCAAT 1 chr5:179719090-179719110 ( 9) CGACCAAT 1 chr2:73298521-73298541 ( 2) GGGCCAAT 1 chr4:775677-775697 ( 10) GAGCCAAT 1 chr16:16002075-16002095 ( 12) GGGCCAAT 1 chr17:47270342-47270362 ( 5) CCGCCAAT 1 chr3:52091417-52091437 ( 1) GGACCAAT 1 chr19:19174697-19174717 ( 11) TCGCCAAT 1 chr16:90143799-90143819 ( 8) CCGCCAAT 1 chr9:80911951-80911971 ( 4) GAACCAAT 1 chr7:100184173-100184193 ( 4) AGGCCAAT 1 chr14:58765088-58765108 ( 5) AAGCCAAT 1 chr19:41284022-41284042 ( 12) CCACCAAT 1 chr9:139844594-139844614 ( 13) CCACCAAT 1 chr17:38574288-38574308 ( 13) AAACCAAT 1 chr16:2955853-2955873 ( 9) AGACCAAT 1 chr19:20959040-20959060 ( 10) CGTCCAAT 1 chr19:21541723-21541743 ( 8) TGTCCAAT 1 chr12:49259713-49259733 ( 13) CGCCCAAT 1 chr16:58663850-58663870 ( 11) TACCCAAT 1 chr6:153304256-153304276 ( 11) GCACCAAT 1 chr3:114866196-114866216 ( 1) ACGCCAAT 1 chr19:3344307-3344327 ( 13) TGGCCTAT 1 chr22:37582486-37582506 ( 7) CTGCCAAT 1 chr7:23053807-23053827 ( 2) CAGCCTAT 1 chr19:41082713-41082733 ( 12) GGCCCAAT 1 chr19:17377996-17378016 ( 12) CGGCCAAA 1 chr19:37808623-37808643 ( 1) TGGCTAAT 1 chr19:46498639-46498659 ( 1) TGGCTAAT 1 chr10:46168278-46168298 ( 12) CCTCCAAT 1 chr22:20067703-20067723 ( 5) CCCCCAAT 1 chr6:32146055-32146075 ( 5) TAGCCATT 1 chr19:14228701-14228721 ( 8) CGGCCATT 1 chr14:102991137-10299115 ( 6) GAGCCTAT 1 chr12:6960521-6960541 ( 13) GAGCCAAA 1 chr2:71454292-71454312 ( 5) GGGCCAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YRRCCAAT MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 6.48023 E= 4.1e-032 -110 57 -65 48 75 -78 61 -332 58 -195 88 -174 -1234 175 -1234 -1234 -1234 169 -1234 -233 219 -1234 -1234 -174 222 -1234 -1234 -233 -184 -1234 -1234 229 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YRRCCAAT MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 52 E= 4.1e-032 0.096154 0.442308 0.192308 0.269231 0.346154 0.173077 0.461538 0.019231 0.307692 0.076923 0.557692 0.057692 0.000000 1.000000 0.000000 0.000000 0.000000 0.961538 0.000000 0.038462 0.942308 0.000000 0.000000 0.057692 0.961538 0.000000 0.000000 0.038462 0.057692 0.000000 0.000000 0.942308 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif YRRCCAAT MEME-1 regular expression -------------------------------------------------------------------------------- [CT][GA][GA]CCAAT -------------------------------------------------------------------------------- Time 1.84 secs. ******************************************************************************** ******************************************************************************** MOTIF ATTGGYBR MEME-2 width = 8 sites = 28 llr = 226 E-value = 3.6e-015 ******************************************************************************** -------------------------------------------------------------------------------- Motif ATTGGYBR MEME-2 Description -------------------------------------------------------------------------------- Simplified A a::::1:3 pos.-specific C :::::641 probability G :::aa:25 matrix T :aa::34: bits 2.4 * * 2.1 *** 1.9 *** 1.7 **** Relative 1.4 ***** Entropy 1.2 ***** (11.7 bits) 0.9 ***** 0.7 ****** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel ATTGGCCG consensus TTA sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTGGYBR MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:48944872-48944892 1 1.22e-05 . ATTGGCTG CGCTGGTCCC chr21:44772639-44772659 7 1.22e-05 TATCTG ATTGGCTG CAGGCA chr7:48075031-48075051 13 1.22e-05 GGCTTCCCCT ATTGGCTG chr14:23755466-23755486 4 1.22e-05 GGT ATTGGCTG CGTGGGCCT chr3:50605211-50605231 6 1.22e-05 CTCCG ATTGGCTG TCGGGCC chr17:44302795-44302815 5 1.22e-05 CGCC ATTGGCTG AGCAATGG chrX:1780640-1780660 1 1.22e-05 . ATTGGCTG AGTCTAGCTG chr6:160183435-160183455 10 2.83e-05 GCCTCTCCC ATTGGTTG GCG chr1:25757263-25757283 13 5.25e-05 GGGCCCTGGG ATTGGCCG chr12:51420191-51420211 1 7.74e-05 . ATTGGTCG ACAGGACGGC chr2:85822783-85822803 8 7.74e-05 TACTCTG ATTGGCCA GCCTC chr3:185826978-185826998 3 7.74e-05 CC ATTGGCCA GAGGCCGTTC chr16:70323496-70323516 13 8.57e-05 ATGAGATATT ATTGGTCA chr11:62495441-62495461 10 8.57e-05 GCCGTTCCG ATTGGTCA TCC chr4:6271467-6271487 4 1.05e-04 GTG ATTGGCGG CTACACCGG chr7:75947451-75947471 3 1.05e-04 CC ATTGGCGG AGCGGGGACA chr22:42342827-42342847 4 1.30e-04 CCT ATTGGTGG GTGCGTCCC chr2:65283399-65283419 11 1.30e-04 GCGTCCACGT ATTGGTGG AG chr19:8478118-8478138 3 1.30e-04 CG ATTGGCGA ATGCAGGCGA chr2:46771320-46771340 2 1.38e-04 C ATTGGTGA GTGGTCTGCC chr4:468013-468033 4 1.72e-04 CTG ATTGGATA TGGGTCCAG chr11:66725908-66725928 7 1.91e-04 CTTCCT ATTGGCCC AGACAG chr3:131100570-131100590 9 2.16e-04 AGGCTCGG ATTGGTCC GAGG chr13:29293185-29293205 13 2.16e-04 CCCAGCGGCG ATTGGTCC chrX:102941744-102941764 6 2.32e-04 AAATG ATTGGACA ACCACCC chr17:80416459-80416479 5 2.68e-04 TGTC ATTGGCCT AGGCAAAG chr19:18315143-18315163 3 3.28e-04 AG ATTGTCTA CGCCCTCCTC chr9:131843281-131843301 3 3.77e-04 TG AATGGCTG CGCCGCTACC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTGGYBR MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:48944872-48944892 1.2e-05 [+2]_12 chr21:44772639-44772659 1.2e-05 6_[+2]_6 chr7:48075031-48075051 1.2e-05 12_[+2] chr14:23755466-23755486 1.2e-05 3_[+2]_9 chr3:50605211-50605231 1.2e-05 5_[+2]_7 chr17:44302795-44302815 1.2e-05 4_[+2]_8 chrX:1780640-1780660 1.2e-05 [+2]_12 chr6:160183435-160183455 2.8e-05 9_[+2]_3 chr1:25757263-25757283 5.2e-05 12_[+2] chr12:51420191-51420211 7.7e-05 [+2]_12 chr2:85822783-85822803 7.7e-05 7_[+2]_5 chr3:185826978-185826998 7.7e-05 2_[+2]_10 chr16:70323496-70323516 8.6e-05 12_[+2] chr11:62495441-62495461 8.6e-05 9_[+2]_3 chr4:6271467-6271487 0.0001 3_[+2]_9 chr7:75947451-75947471 0.0001 2_[+2]_10 chr22:42342827-42342847 0.00013 3_[+2]_9 chr2:65283399-65283419 0.00013 10_[+2]_2 chr19:8478118-8478138 0.00013 2_[+2]_10 chr2:46771320-46771340 0.00014 1_[+2]_11 chr4:468013-468033 0.00017 3_[+2]_9 chr11:66725908-66725928 0.00019 6_[+2]_6 chr3:131100570-131100590 0.00022 8_[+2]_4 chr13:29293185-29293205 0.00022 12_[+2] chrX:102941744-102941764 0.00023 5_[+2]_7 chr17:80416459-80416479 0.00027 4_[+2]_8 chr19:18315143-18315163 0.00033 2_[+2]_10 chr9:131843281-131843301 0.00038 2_[+2]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTGGYBR MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ATTGGYBR width=8 seqs=28 chr17:48944872-48944892 ( 1) ATTGGCTG 1 chr21:44772639-44772659 ( 7) ATTGGCTG 1 chr7:48075031-48075051 ( 13) ATTGGCTG 1 chr14:23755466-23755486 ( 4) ATTGGCTG 1 chr3:50605211-50605231 ( 6) ATTGGCTG 1 chr17:44302795-44302815 ( 5) ATTGGCTG 1 chrX:1780640-1780660 ( 1) ATTGGCTG 1 chr6:160183435-160183455 ( 10) ATTGGTTG 1 chr1:25757263-25757283 ( 13) ATTGGCCG 1 chr12:51420191-51420211 ( 1) ATTGGTCG 1 chr2:85822783-85822803 ( 8) ATTGGCCA 1 chr3:185826978-185826998 ( 3) ATTGGCCA 1 chr16:70323496-70323516 ( 13) ATTGGTCA 1 chr11:62495441-62495461 ( 10) ATTGGTCA 1 chr4:6271467-6271487 ( 4) ATTGGCGG 1 chr7:75947451-75947471 ( 3) ATTGGCGG 1 chr22:42342827-42342847 ( 4) ATTGGTGG 1 chr2:65283399-65283419 ( 11) ATTGGTGG 1 chr19:8478118-8478138 ( 3) ATTGGCGA 1 chr2:46771320-46771340 ( 2) ATTGGTGA 1 chr4:468013-468033 ( 4) ATTGGATA 1 chr11:66725908-66725928 ( 7) ATTGGCCC 1 chr3:131100570-131100590 ( 9) ATTGGTCC 1 chr13:29293185-29293205 ( 13) ATTGGTCC 1 chrX:102941744-102941764 ( 6) ATTGGACA 1 chr17:80416459-80416479 ( 5) ATTGGCCT 1 chr19:18315143-18315163 ( 3) ATTGTCTA 1 chr9:131843281-131843301 ( 3) AATGGCTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTGGYBR MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.07592 E= 3.6e-015 228 -1145 -1145 -1145 -253 -1145 -1145 232 -1145 -1145 -1145 237 -1145 -1145 173 -1145 -1145 -1145 167 -243 -153 103 -1145 74 -1145 40 -50 102 64 -148 82 -243 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTGGYBR MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 28 E= 3.6e-015 1.000000 0.000000 0.000000 0.000000 0.035714 0.000000 0.000000 0.964286 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.964286 0.035714 0.071429 0.607143 0.000000 0.321429 0.000000 0.392857 0.214286 0.392857 0.321429 0.107143 0.535714 0.035714 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ATTGGYBR MEME-2 regular expression -------------------------------------------------------------------------------- ATTGG[CT][CTG][GA] -------------------------------------------------------------------------------- Time 2.63 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTGTTTG MEME-3 width = 8 sites = 2 llr = 25 E-value = 6.6e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTGTTTG MEME-3 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C :::::::: probability G :::a:::a matrix T aaa:aaa: bits 2.4 *** *** 2.1 *** *** 1.9 *** *** 1.7 ******** Relative 1.4 ******** Entropy 1.2 ******** (17.7 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTTGTTTG consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTTTG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr17:38574288-38574308 2 4.71e-06 G TTTGTTTG AATAAACCAA chr22:38054414-38054434 10 4.71e-06 GCTTCGCGT TTTGTTTG TAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTTTG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr17:38574288-38574308 4.7e-06 1_[+3]_11 chr22:38054414-38054434 4.7e-06 9_[+3]_3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTTTG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTGTTTG width=8 seqs=2 chr17:38574288-38574308 ( 2) TTTGTTTG 1 chr22:38054414-38054434 ( 10) TTTGTTTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTTTG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 10.6653 E= 6.6e+002 -765 -765 -765 237 -765 -765 -765 237 -765 -765 -765 237 -765 -765 172 -765 -765 -765 -765 237 -765 -765 -765 237 -765 -765 -765 237 -765 -765 172 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTTTG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 6.6e+002 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTGTTTG MEME-3 regular expression -------------------------------------------------------------------------------- TTTGTTTG -------------------------------------------------------------------------------- Time 5.60 secs. ******************************************************************************** ******************************************************************************** MOTIF GTCACGTG MEME-4 width = 8 sites = 11 llr = 94 E-value = 1.6e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif GTCACGTG MEME-4 Description -------------------------------------------------------------------------------- Simplified A 21:a:2:: pos.-specific C 22a:9::: probability G 6::::8:a matrix T :7::1:a: bits 2.4 * * 2.1 * * 1.9 * * 1.7 ** ** Relative 1.4 *** ** Entropy 1.2 ******* (12.3 bits) 0.9 ******* 0.7 ******* 0.5 ******** 0.2 ******** 0.0 -------- Multilevel GTCACGTG consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTCACGTG MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:39325543-39325563 6 1.88e-05 GCCCC GTCACGTG CCGGAAT chr13:50159705-50159725 12 1.88e-05 GGCCCGCCGG GTCACGTG G chr17:80455127-80455147 1 1.88e-05 . GTCACGTG GGAGGTCACG chr1:173446184-173446204 10 3.16e-05 GAGCCCCGC ATCACGTG TGC chr1:155211067-155211087 13 4.44e-05 GACTAGGAGC GTCACATG chr12:121342215-12134223 4 6.29e-05 ACG CTCACGTG ATGCGCGCC chr16:1525062-1525082 7 9.19e-05 GACGGG GCCACGTG ATGAGC chrX:101975611-101975631 11 1.04e-04 CTGACGGTGG GTCATGTG AC chr11:6640663-6640683 3 1.13e-04 GG ATCACATG AGCTCTATAT chr13:30969742-30969762 8 1.33e-04 TGACCTG GACACGTG ACTTG chr17:46688412-46688432 3 2.44e-04 CG CCCACGTG ACGTCCCCTC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTCACGTG MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:39325543-39325563 1.9e-05 5_[+4]_7 chr13:50159705-50159725 1.9e-05 11_[+4]_1 chr17:80455127-80455147 1.9e-05 [+4]_12 chr1:173446184-173446204 3.2e-05 9_[+4]_3 chr1:155211067-155211087 4.4e-05 12_[+4] chr12:121342215-12134223 6.3e-05 3_[+4]_9 chr16:1525062-1525082 9.2e-05 6_[+4]_6 chrX:101975611-101975631 0.0001 10_[+4]_2 chr11:6640663-6640683 0.00011 2_[+4]_10 chr13:30969742-30969762 0.00013 7_[+4]_5 chr17:46688412-46688432 0.00024 2_[+4]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTCACGTG MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GTCACGTG width=8 seqs=11 chr1:39325543-39325563 ( 6) GTCACGTG 1 chr13:50159705-50159725 ( 12) GTCACGTG 1 chr17:80455127-80455147 ( 1) GTCACGTG 1 chr1:173446184-173446204 ( 10) ATCACGTG 1 chr1:155211067-155211087 ( 13) GTCACATG 1 chr12:121342215-12134223 ( 4) CTCACGTG 1 chr16:1525062-1525082 ( 7) GCCACGTG 1 chrX:101975611-101975631 ( 11) GTCATGTG 1 chr11:6640663-6640683 ( 3) ATCACATG 1 chr13:30969742-30969762 ( 8) GACACGTG 1 chr17:46688412-46688432 ( 3) CCCACGTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTCACGTG MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.55806 E= 1.6e+003 -18 -71 107 -1010 -118 -71 -1010 191 -1010 174 -1010 -1010 228 -1010 -1010 -1010 -1010 161 -1010 -108 -18 -1010 144 -1010 -1010 -1010 -1010 237 -1010 -1010 172 -1010 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTCACGTG MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 11 E= 1.6e+003 0.181818 0.181818 0.636364 0.000000 0.090909 0.181818 0.000000 0.727273 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.909091 0.000000 0.090909 0.181818 0.000000 0.818182 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GTCACGTG MEME-4 regular expression -------------------------------------------------------------------------------- GTCACGTG -------------------------------------------------------------------------------- Time 8.63 secs. ******************************************************************************** ******************************************************************************** MOTIF TDCTKCMT MEME-5 width = 8 sites = 7 llr = 65 E-value = 2.5e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TDCTKCMT MEME-5 Description -------------------------------------------------------------------------------- Simplified A :3::::6: pos.-specific C ::a::a4: probability G :3::4::: matrix T a4:a6::a bits 2.4 * * * 2.1 * * * 1.9 * * * 1.7 * ** * * Relative 1.4 * ** * * Entropy 1.2 * **** * (13.4 bits) 0.9 * ****** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTCTTCAT consensus A G C sequence G -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TDCTKCMT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:122028229-12202824 7 1.01e-05 AAGCAT TACTTCAT CATACT chr12:56211742-56211762 1 2.49e-05 . TTCTGCAT TACAGACCAC chr19:19174697-19174717 1 3.25e-05 . TGCTTCAT ACTCGCCAAT chr11:107798923-10779894 4 3.25e-05 CCT TGCTTCAT TTTCCTTGG chr2:73460487-73460507 7 4.01e-05 TTAGCC TACTTCCT ATTGGT chr17:43138946-43138966 9 5.94e-05 CACTAGGA TTCTGCCT GGCG chr5:89705635-89705655 8 5.94e-05 GCTATGG TTCTGCCT ATTAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TDCTKCMT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:122028229-12202824 1e-05 6_[+5]_6 chr12:56211742-56211762 2.5e-05 [+5]_12 chr19:19174697-19174717 3.3e-05 [+5]_12 chr11:107798923-10779894 3.3e-05 3_[+5]_9 chr2:73460487-73460507 4e-05 6_[+5]_6 chr17:43138946-43138966 5.9e-05 8_[+5]_4 chr5:89705635-89705655 5.9e-05 7_[+5]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TDCTKCMT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TDCTKCMT width=8 seqs=7 chr12:122028229-12202824 ( 7) TACTTCAT 1 chr12:56211742-56211762 ( 1) TTCTGCAT 1 chr19:19174697-19174717 ( 1) TGCTTCAT 1 chr11:107798923-10779894 ( 4) TGCTTCAT 1 chr2:73460487-73460507 ( 7) TACTTCCT 1 chr17:43138946-43138966 ( 9) TTCTGCCT 1 chr5:89705635-89705655 ( 8) TTCTGCCT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TDCTKCMT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 10.0799 E= 2.5e+003 -945 -945 -945 237 47 -945 -8 115 -945 174 -945 -945 -945 -945 -945 237 -945 -945 50 156 -945 174 -945 -945 147 52 -945 -945 -945 -945 -945 237 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TDCTKCMT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 7 E= 2.5e+003 0.000000 0.000000 0.000000 1.000000 0.285714 0.000000 0.285714 0.428571 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.428571 0.571429 0.000000 1.000000 0.000000 0.000000 0.571429 0.428571 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TDCTKCMT MEME-5 regular expression -------------------------------------------------------------------------------- T[TAG]CT[TG]C[AC]T -------------------------------------------------------------------------------- Time 11.69 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:40728068-40728088 9.98e-01 20 chr19:46148936-46148956 8.03e-01 20 chr19:4471717-4471737 2.56e-03 6_[+1(5.48e-05)]_6 chr17:80455127-80455147 5.10e-02 [+4(1.88e-05)]_4_[+4(1.88e-05)] chr7:75947451-75947471 1.63e-01 20 chrX:47221685-47221705 8.25e-01 20 chrX:47415621-47415641 3.58e-01 20 chr19:1041126-1041146 9.58e-01 20 chr19:2841383-2841403 7.67e-01 20 chr16:4852973-4852993 5.25e-01 20 chr5:179719090-179719110 1.62e-01 8_[+1(9.22e-05)]_4 chr5:32313341-32313361 1.24e-01 [+1(9.22e-05)]_12 chr1:10270473-10270493 8.07e-01 20 chr9:80911951-80911971 3.84e-02 20 chr15:69113316-69113336 1.97e-02 5_[+1(5.48e-05)]_7 chr11:560871-560891 9.98e-01 20 chr17:47866566-47866586 9.60e-01 20 chr11:17298189-17298209 4.17e-01 20 chr3:100211369-100211389 5.32e-01 20 chr20:56004973-56004993 1.93e-01 20 chr19:19249330-19249350 8.85e-01 20 chr13:107188077-10718809 9.68e-01 20 chr19:2945026-2945046 9.08e-01 20 chr20:17663022-17663042 9.41e-01 20 chr19:37288257-37288277 3.53e-01 20 chr19:4342899-4342919 2.34e-01 20 chr22:20004448-20004468 8.90e-01 20 chr19:18654422-18654442 5.61e-01 20 chr13:50159705-50159725 7.36e-02 11_[+4(1.88e-05)]_1 chr1:25757263-25757283 3.04e-02 12_[+2(5.25e-05)] chr2:71454292-71454312 8.20e-02 20 chr6:80247202-80247222 7.64e-02 20 chr1:54204947-54204967 9.99e-01 20 chr11:34379633-34379653 5.82e-01 20 chr13:26796027-26796047 1.50e-01 12_[+1(9.22e-05)] chr3:114866196-114866216 5.58e-03 20 chrX:1780640-1780660 5.65e-03 [+2(1.22e-05)]_12 chr13:30969742-30969762 9.37e-02 20 chr13:20532768-20532788 9.65e-01 20 chr11:13299095-13299115 5.59e-01 20 chr16:87351049-87351069 2.95e-01 20 chr17:44302795-44302815 1.61e-03 4_[+2(1.22e-05)]_8 chr16:2955853-2955873 7.03e-02 20 chr4:175204409-175204429 4.52e-01 20 chr11:4629550-4629570 6.34e-01 20 chr19:13906104-13906124 7.85e-01 20 chr3:149530944-149530964 1.56e-02 20 chr6:158653181-158653201 9.79e-01 20 chr16:16002075-16002095 3.12e-02 20 chr1:167691157-167691177 8.96e-01 20 chr11:134093925-13409394 2.57e-01 20 chr6:122720626-122720646 6.08e-01 20 chr5:89705635-89705655 8.42e-04 7_[+5(5.94e-05)]_5 chr21:45175118-45175138 8.68e-01 20 chr1:232765971-232765991 9.04e-01 20 chr10:101190507-10119052 8.99e-01 20 chr3:50605211-50605231 8.47e-03 5_[+2(1.22e-05)]_7 chr12:6960521-6960541 2.57e-01 20 chr19:1133745-1133765 8.10e-01 20 chrX:48958228-48958248 3.10e-01 20 chr20:40247103-40247123 5.36e-01 20 chr22:20067703-20067723 2.18e-01 20 chr16:58663850-58663870 3.87e-02 20 chr1:28562522-28562542 4.19e-01 20 chr12:14927216-14927236 4.97e-01 20 chr12:53473239-53473259 9.66e-01 20 chr9:135905977-135905997 8.55e-01 20 chr19:8478118-8478138 3.37e-02 20 chr12:109535809-10953582 5.64e-01 20 chr2:65283399-65283419 8.83e-03 20 chr19:6372650-6372670 9.89e-01 20 chr12:112451178-11245119 9.95e-01 20 chr16:57570007-57570027 9.48e-01 20 chr22:42342827-42342847 3.40e-02 20 chr19:42580192-42580212 3.16e-01 20 chr19:41082713-41082733 9.65e-02 20 chr14:74960331-74960351 5.83e-01 20 chr1:227127827-227127847 5.31e-01 20 chr6:153304256-153304276 1.64e-01 20 chr8:145159286-145159306 9.60e-01 20 chr19:21105984-21106004 9.43e-01 20 chr13:73633035-73633055 7.70e-01 20 chr3:185826978-185826998 2.59e-02 2_[+2(7.74e-05)]_10 chr22:35696178-35696198 5.79e-01 20 chr1:150602221-150602241 9.67e-01 20 chr11:6640663-6640683 1.70e-02 20 chr19:54641317-54641337 9.68e-01 20 chr19:17420260-17420280 1.25e-02 5_[+1(5.48e-05)]_7 chr16:2264957-2264977 1.00e+00 20 chr12:121342215-12134223 6.14e-02 3_[+4(6.29e-05)]_9 chr14:78083238-78083258 9.84e-01 20 chr2:46771320-46771340 6.19e-03 20 chr3:152879093-152879113 1.10e-02 12_[+1(5.48e-05)] chr13:29293185-29293205 7.81e-02 20 chr19:21541723-21541743 6.59e-02 20 chr14:23755466-23755486 2.09e-03 3_[+2(1.22e-05)]_9 chr11:66725908-66725928 8.43e-03 20 chr1:155211067-155211087 6.42e-02 12_[+4(4.44e-05)] chr16:46723507-46723527 9.34e-01 20 chr17:80416459-80416479 1.02e-02 20 chr8:25316036-25316056 7.05e-01 20 chr4:775677-775697 1.39e-01 20 chr17:41978050-41978070 9.72e-01 20 chr8:144450906-144450926 5.18e-01 20 chr22:40440249-40440269 1.70e-02 20 chr16:1876867-1876887 7.26e-01 20 chr16:30621765-30621785 9.53e-01 20 chr1:85527930-85527950 7.96e-01 20 chr19:20959040-20959060 2.09e-01 20 chr15:83478282-83478302 9.78e-02 20 chr15:90895413-90895433 9.96e-01 20 chr17:46688412-46688432 2.03e-01 20 chr2:232646051-232646071 3.71e-01 20 chrX:154444609-154444629 7.89e-01 20 chrX:47420527-47420547 9.89e-01 20 chr10:46168278-46168298 2.50e-02 20 chr19:46498639-46498659 4.52e-02 20 chr17:43138946-43138966 3.47e-02 8_[+5(5.94e-05)]_4 chr5:145583063-145583083 9.00e-01 20 chr19:40931803-40931823 9.43e-01 20 chr17:2952393-2952413 9.65e-01 20 chr7:23053807-23053827 2.01e-01 20 chr14:54863601-54863621 2.12e-01 20 chr4:166248743-166248763 9.83e-01 20 chr11:71814513-71814533 8.89e-01 20 chr17:74667934-74667954 1.86e-01 20 chrX:101975611-101975631 1.60e-02 20 chr19:37808623-37808643 1.59e-02 20 chr19:3035709-3035729 9.37e-03 5_[+1(5.48e-05)]_7 chr1:150601703-150601723 8.14e-01 20 chr20:44441141-44441161 8.83e-01 20 chr3:131100570-131100590 6.00e-02 20 chr19:15947945-15947965 5.28e-01 20 chr1:173446184-173446204 4.35e-02 9_[+4(3.16e-05)]_3 chr5:43313854-43313874 2.98e-02 11_[+1(9.22e-05)]_1 chr22:37172268-37172288 1.90e-02 20 chr17:79196853-79196873 9.13e-01 20 chr7:48075031-48075051 2.92e-04 12_[+2(1.22e-05)] chr19:33166143-33166163 5.90e-01 20 chr11:107798923-10779894 5.40e-04 3_[+5(3.25e-05)]_9 chr11:62495441-62495461 4.69e-03 9_[+2(8.57e-05)]_3 chr11:68228085-68228105 9.89e-01 20 chr15:90118606-90118626 3.99e-01 20 chr4:89513541-89513561 8.63e-01 20 chr2:73460487-73460507 6.20e-03 6_[+5(4.01e-05)]_6 chr15:43213085-43213105 9.33e-01 20 chr17:8534271-8534291 7.86e-01 20 chr15:64673769-64673789 2.94e-01 20 chr19:36193369-36193389 9.82e-01 20 chr22:37582486-37582506 2.50e-02 20 chr17:17184085-17184105 9.31e-01 20 chr18:14132517-14132537 6.91e-01 20 chr9:133588157-133588177 9.43e-01 20 chr14:73393105-73393125 6.33e-02 20 chr19:3344307-3344327 1.47e-02 20 chr12:123868604-12386862 9.24e-01 20 chr1:6845327-6845347 3.08e-02 1_[+1(9.22e-05)]_11 chr3:148804366-148804386 9.98e-01 20 chr6:160183435-160183455 2.88e-04 9_[+2(2.83e-05)]_3 chr12:56211742-56211762 1.85e-02 [+5(2.49e-05)]_12 chr12:125534246-12553426 9.87e-01 20 chr22:38054414-38054434 8.75e-04 9_[+3(4.71e-06)]_3 chr8:11660040-11660060 7.02e-01 20 chr19:54640807-54640827 3.25e-01 20 chr13:20207734-20207754 4.09e-03 20 chr2:73298521-73298541 8.96e-02 20 chrX:49125650-49125670 5.33e-01 20 chr19:58790204-58790224 3.89e-01 20 chrX:102941744-102941764 8.09e-02 20 chr19:18315143-18315163 2.65e-02 20 chr6:31126228-31126248 2.27e-01 20 chr15:86338208-86338228 5.36e-01 20 chr19:14228701-14228721 2.15e-01 20 chr6:27862264-27862284 4.14e-02 20 chr17:38574288-38574308 4.42e-05 1_[+3(4.71e-06)]_11 chr2:85822783-85822803 5.16e-03 7_[+2(7.74e-05)]_5 chr12:49259713-49259733 5.71e-02 20 chr14:102991137-10299115 1.60e-01 20 chr12:51420191-51420211 4.53e-02 [+2(7.74e-05)]_12 chr10:99052451-99052471 1.78e-01 20 chr12:113658981-11365900 2.07e-01 20 chr16:90143799-90143819 1.62e-01 20 chr1:38397550-38397570 2.76e-02 20 chr6:32146055-32146075 1.97e-02 20 chr15:44487574-44487594 9.23e-01 20 chr16:67217593-67217613 8.95e-01 20 chr11:124981570-12498159 5.76e-01 20 chr19:17377996-17378016 2.27e-02 20 chr14:58765088-58765108 4.47e-02 20 chr9:34989599-34989619 1.01e-01 20 chr9:139844594-139844614 2.36e-01 20 chr6:33422260-33422280 1.33e-01 20 chr7:150076329-150076349 8.63e-01 20 chr19:1507868-1507888 9.63e-01 20 chr21:44772639-44772659 6.10e-04 6_[+2(1.22e-05)]_6 chr9:86595190-86595210 7.87e-01 20 chr13:41240839-41240859 6.79e-03 [+1(5.48e-05)]_12 chr1:153895589-153895609 4.24e-01 20 chr3:126423017-126423037 4.65e-02 12_[+1(5.48e-05)] chr14:94492634-94492654 7.11e-01 20 chr2:10262763-10262783 4.42e-02 6_[+1(5.48e-05)]_6 chr6:82957518-82957538 2.88e-02 20 chr9:139780779-139780799 4.51e-01 20 chr22:21996449-21996469 9.40e-01 20 chr17:48944872-48944892 2.51e-03 [+2(1.22e-05)]_12 chr19:7894880-7894900 1.18e-01 20 chr14:74551241-74551261 4.02e-01 20 chr11:58874577-58874597 3.07e-01 20 chr19:19174697-19174717 5.80e-04 [+5(3.25e-05)]_12 chr6:27806243-27806263 4.70e-01 20 chr3:93698901-93698921 6.00e-01 20 chr17:80656643-80656663 5.44e-01 20 chr2:159313321-159313341 9.75e-01 20 chr16:3054062-3054082 9.85e-01 20 chr9:131843281-131843301 2.25e-01 20 chr16:22386034-22386054 3.47e-01 20 chr11:67275765-67275785 9.89e-01 20 chr5:98109236-98109256 5.74e-02 10_[+1(9.22e-05)]_2 chr1:112282090-112282110 4.05e-01 20 chr1:15930163-15930183 3.63e-01 20 chr12:122028229-12202824 3.89e-03 6_[+5(1.01e-05)]_6 chr3:52091417-52091437 5.72e-02 20 chr17:73452640-73452660 9.03e-02 8_[+1(9.22e-05)]_4 chr19:8408206-8408226 9.87e-01 20 chr4:6271467-6271487 4.94e-02 20 chr1:43312175-43312195 1.56e-02 12_[+1(5.48e-05)] chr16:70323496-70323516 7.55e-03 12_[+2(8.57e-05)] chr9:37465761-37465781 5.16e-02 7_[+1(9.22e-05)]_5 chr6:159527947-159527967 8.52e-02 11_[+1(9.22e-05)]_1 chr19:45873925-45873945 8.83e-01 20 chr10:102790934-10279095 8.71e-01 20 chr17:16945646-16945666 9.54e-01 20 chr3:39425831-39425851 9.95e-01 20 chr19:18133125-18133145 2.84e-01 20 chr4:468013-468033 8.34e-02 20 chr16:31724510-31724530 9.26e-01 20 chr19:4472104-4472124 4.03e-01 20 chr15:77223953-77223973 3.02e-02 20 chr1:41174925-41174945 8.40e-01 20 chr13:20437871-20437891 4.82e-01 20 chr17:47270342-47270362 2.96e-02 20 chr1:39325543-39325563 5.23e-02 5_[+4(1.88e-05)]_7 chr16:27386603-27386623 4.14e-01 20 chr7:100184173-100184193 2.58e-02 20 chr1:109940653-109940673 7.18e-01 20 chr19:49224053-49224073 4.12e-01 20 chr16:1525062-1525082 9.70e-02 6_[+4(9.19e-05)]_6 chr16:88923500-88923520 5.26e-01 20 chr19:41284022-41284042 5.00e-02 20 chr6:27100701-27100721 9.76e-01 20 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n09.farnam.hpc.yale.internal ********************************************************************************