******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/E4F1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr14:57857288-57857308 1.0000 20 chr17:7232835-7232855 1.0000 20 chr22:20307616-20307636 1.0000 20 chrX:119737854-119737874 1.0000 20 chrX:153639820-153639840 1.0000 20 chr1:11986514-11986534 1.0000 20 chr19:46850339-46850359 1.0000 20 chr15:59279909-59279929 1.0000 20 chr17:79519487-79519507 1.0000 20 chr1:111682857-111682877 1.0000 20 chr1:92949478-92949498 1.0000 20 chr9:108320391-108320411 1.0000 20 chr10:75173105-75173125 1.0000 20 chr4:87855910-87855930 1.0000 20 chr10:31607938-31607958 1.0000 20 chr2:120436770-120436790 1.0000 20 chr1:161068114-161068134 1.0000 20 chr20:247662-247682 1.0000 20 chr1:39491974-39491994 1.0000 20 chr1:77685120-77685140 1.0000 20 chr16:74402122-74402142 1.0000 20 chr16:67143851-67143871 1.0000 20 chr16:70148162-70148182 1.0000 20 chrX:129040099-129040119 1.0000 20 chr3:196019352-196019372 1.0000 20 chr2:101869366-101869386 1.0000 20 chr1:15943781-15943801 1.0000 20 chr15:72410754-72410774 1.0000 20 chr9:115983556-115983576 1.0000 20 chr3:12525956-12525976 1.0000 20 chr7:155437158-155437178 1.0000 20 chr16:47495044-47495064 1.0000 20 chr18:54318505-54318525 1.0000 20 chr6:112408716-112408736 1.0000 20 chr3:180707505-180707525 1.0000 20 chr15:52263959-52263979 1.0000 20 chr6:166796548-166796568 1.0000 20 chr16:15736999-15737019 1.0000 20 chr4:6711612-6711632 1.0000 20 chr4:142142079-142142099 1.0000 20 chr20:36322398-36322418 1.0000 20 chr1:220220026-220220046 1.0000 20 chr12:48577356-48577376 1.0000 20 chr1:38388586-38388606 1.0000 20 chr14:96828498-96828518 1.0000 20 chr1:86174123-86174143 1.0000 20 chr1:171750379-171750399 1.0000 20 chr6:119214777-119214797 1.0000 20 chr4:6675743-6675763 1.0000 20 chr17:4046351-4046371 1.0000 20 chr2:128568430-128568450 1.0000 20 chr10:120514495-12051451 1.0000 20 chr8:86019286-86019306 1.0000 20 chr16:58888494-58888514 1.0000 20 chr2:85788696-85788716 1.0000 20 chr20:5986685-5986705 1.0000 20 chr15:101142624-10114264 1.0000 20 chr13:80055247-80055267 1.0000 20 chrX:153640023-153640043 1.0000 20 chr14:36278522-36278542 1.0000 20 chr7:107531475-107531495 1.0000 20 chr1:231473691-231473711 1.0000 20 chr13:26828101-26828121 1.0000 20 chr1:53686203-53686223 1.0000 20 chr1:160232300-160232320 1.0000 20 chr10:70748514-70748534 1.0000 20 chr12:25348255-25348275 1.0000 20 chr4:6642367-6642387 1.0000 20 chr8:41348035-41348055 1.0000 20 chr20:30135129-30135149 1.0000 20 chr2:241500610-241500630 1.0000 20 chr14:21134779-21134799 1.0000 20 chr19:7745772-7745792 1.0000 20 chr6:107780796-107780816 1.0000 20 chr10:38691676-38691696 1.0000 20 chr11:111896049-11189606 1.0000 20 chr7:22862481-22862501 1.0000 20 chr6:6657842-6657862 1.0000 20 chr1:154245044-154245064 1.0000 20 chr5:110848393-110848413 1.0000 20 chrX:135578943-135578963 1.0000 20 chr9:7799780-7799800 1.0000 20 chr19:52552062-52552082 1.0000 20 chr22:42177252-42177272 1.0000 20 chr14:104028797-10402881 1.0000 20 chr16:85833176-85833196 1.0000 20 chr12:53400053-53400073 1.0000 20 chr3:99979820-99979840 1.0000 20 chr2:74191036-74191056 1.0000 20 chr11:64795141-64795161 1.0000 20 chr17:73127963-73127983 1.0000 20 chr8:66864012-66864032 1.0000 20 chr17:80408673-80408693 1.0000 20 chr7:72722836-72722856 1.0000 20 chr1:19372118-19372138 1.0000 20 chr3:127309658-127309678 1.0000 20 chr1:714279-714299 1.0000 20 chr1:224180521-224180541 1.0000 20 chr15:43398296-43398316 1.0000 20 chr17:4699388-4699408 1.0000 20 chr4:6717838-6717858 1.0000 20 chr2:32264876-32264896 1.0000 20 chr6:113970605-113970625 1.0000 20 chr2:114341612-114341632 1.0000 20 chr8:33370679-33370699 1.0000 20 chr1:87380032-87380052 1.0000 20 chr11:107328528-10732854 1.0000 20 chr5:93447354-93447374 1.0000 20 chr19:53360810-53360830 1.0000 20 chr16:69760415-69760435 1.0000 20 chr6:31670887-31670907 1.0000 20 chr2:149402962-149402982 1.0000 20 chr7:5271947-5271967 1.0000 20 chr3:141456842-141456862 1.0000 20 chr16:50781224-50781244 1.0000 20 chr17:80358868-80358888 1.0000 20 chr16:284587-284607 1.0000 20 chr2:172778765-172778785 1.0000 20 chr16:31084622-31084642 1.0000 20 chr5:180616843-180616863 1.0000 20 chr4:123843237-123843257 1.0000 20 chr5:96518970-96518990 1.0000 20 chr1:101491393-101491413 1.0000 20 chr19:48836387-48836407 1.0000 20 chr11:85956156-85956176 1.0000 20 chr19:38865426-38865446 1.0000 20 chr14:104029340-10402936 1.0000 20 chr11:66050071-66050091 1.0000 20 chr3:129158828-129158848 1.0000 20 chr11:43665777-43665797 1.0000 20 chr1:22109638-22109658 1.0000 20 chr19:18263453-18263473 1.0000 20 chr4:88343744-88343764 1.0000 20 chr17:41322461-41322481 1.0000 20 chr19:53073588-53073608 1.0000 20 chr9:127962760-127962780 1.0000 20 chr19:18434051-18434071 1.0000 20 chr19:2622725-2622745 1.0000 20 chr12:30848820-30848840 1.0000 20 chr10:130262798-13026281 1.0000 20 chr2:7888944-7888964 1.0000 20 chr3:52719991-52720011 1.0000 20 chr8:92082277-92082297 1.0000 20 chr14:24036952-24036972 1.0000 20 chr3:133292012-133292032 1.0000 20 chr1:56798025-56798045 1.0000 20 chr4:166248674-166248694 1.0000 20 chr6:43968302-43968322 1.0000 20 chr11:207586-207606 1.0000 20 chr5:140079993-140080013 1.0000 20 chr10:75007085-75007105 1.0000 20 chr15:40615702-40615722 1.0000 20 chr10:106098388-10609840 1.0000 20 chr10:105127664-10512768 1.0000 20 chr19:38865625-38865645 1.0000 20 chr17:40346537-40346557 1.0000 20 chr1:89149904-89149924 1.0000 20 chr19:53898429-53898449 1.0000 20 chr11:85339571-85339591 1.0000 20 chr19:41082739-41082759 1.0000 20 chr14:60558778-60558798 1.0000 20 chr12:106696431-10669645 1.0000 20 chr20:47131937-47131957 1.0000 20 chr2:65584897-65584917 1.0000 20 chr16:89392600-89392620 1.0000 20 chr22:42228959-42228979 1.0000 20 chr4:6676389-6676409 1.0000 20 chr10:105881882-10588190 1.0000 20 chr2:172544022-172544042 1.0000 20 chr1:234659471-234659491 1.0000 20 chr1:2480309-2480329 1.0000 20 chr2:27440305-27440325 1.0000 20 chr12:64616054-64616074 1.0000 20 chr19:39926638-39926658 1.0000 20 chr19:41284131-41284151 1.0000 20 chr13:95248409-95248429 1.0000 20 chr6:24721572-24721592 1.0000 20 chr17:4901049-4901069 1.0000 20 chr10:1094952-1094972 1.0000 20 chr1:231376910-231376930 1.0000 20 chr1:115642182-115642202 1.0000 20 chr12:50794484-50794504 1.0000 20 chr1:249120440-249120460 1.0000 20 chr8:55047702-55047722 1.0000 20 chr7:149535465-149535485 1.0000 20 chr22:47130977-47130997 1.0000 20 chr22:46525427-46525447 1.0000 20 chr19:49141153-49141173 1.0000 20 chr16:77225016-77225036 1.0000 20 chr16:88877888-88877908 1.0000 20 chr16:15068758-15068778 1.0000 20 chr4:159593493-159593513 1.0000 20 chr11:47869663-47869683 1.0000 20 chr1:111991959-111991979 1.0000 20 chr7:98923505-98923525 1.0000 20 chr8:126010593-126010613 1.0000 20 chr8:22526631-22526651 1.0000 20 chr18:3261895-3261915 1.0000 20 chr2:122407266-122407286 1.0000 20 chr3:119419506-119419526 1.0000 20 chr4:110736666-110736686 1.0000 20 chr19:39109757-39109777 1.0000 20 chr6:58313024-58313044 1.0000 20 chr10:74091912-74091932 1.0000 20 chr1:24104981-24105001 1.0000 20 chr12:108908952-10890897 1.0000 20 chr1:210001295-210001315 1.0000 20 chr10:97890044-97890064 1.0000 20 chr10:103892377-10389239 1.0000 20 chr1:235324557-235324577 1.0000 20 chr2:203776617-203776637 1.0000 20 chr20:60982595-60982615 1.0000 20 chr13:76112101-76112121 1.0000 20 chr18:12991229-12991249 1.0000 20 chr16:10480836-10480856 1.0000 20 chr19:58912809-58912829 1.0000 20 chr10:112201617-11220163 1.0000 20 chr6:31671088-31671108 1.0000 20 chr1:110026866-110026886 1.0000 20 chr22:18560641-18560661 1.0000 20 chr17:56296585-56296605 1.0000 20 chr4:159731499-159731519 1.0000 20 chr5:43313815-43313835 1.0000 20 chr16:4475531-4475551 1.0000 20 chr14:21979566-21979586 1.0000 20 chr20:32890895-32890915 1.0000 20 chr9:101018204-101018224 1.0000 20 chr9:100807871-100807891 1.0000 20 chr4:4526308-4526328 1.0000 20 chr3:49131807-49131827 1.0000 20 chr9:19103045-19103065 1.0000 20 chr1:109618712-109618732 1.0000 20 chr17:8093565-8093585 1.0000 20 chr17:7589684-7589704 1.0000 20 chr22:18484480-18484500 1.0000 20 chr17:80551004-80551024 1.0000 20 chr11:114271330-11427135 1.0000 20 chr19:1940890-1940910 1.0000 20 chr14:60715665-60715685 1.0000 20 chr17:27046734-27046754 1.0000 20 chr7:21985668-21985688 1.0000 20 chr19:3557728-3557748 1.0000 20 chr19:36704952-36704972 1.0000 20 chr12:88535884-88535904 1.0000 20 chr18:23670749-23670769 1.0000 20 chr1:42928807-42928827 1.0000 20 chr10:97889824-97889844 1.0000 20 chr15:55611359-55611379 1.0000 20 chr17:4634719-4634739 1.0000 20 chr1:110091181-110091201 1.0000 20 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/GM12878/inference_raw/MEME/RankLinear0.6_10_E4F1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/E4F1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 5000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 5000 norand= no csites= 1000 Letter frequencies in dataset: A 0.198 C 0.301 G 0.308 T 0.193 Background letter frequencies (from file dataset with add-one prior applied): A 0.198 C 0.301 G 0.308 T 0.193 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF GYCGTAAA MEME-1 width = 8 sites = 24 llr = 217 E-value = 6.7e-020 ******************************************************************************** -------------------------------------------------------------------------------- Motif GYCGTAAA MEME-1 Description -------------------------------------------------------------------------------- Simplified A 2::::9a9 pos.-specific C :7a::::: probability G 8::a:1:: matrix T :3::a::1 bits 2.4 2.1 * * 1.9 *** 1.7 ***** Relative 1.4 ****** Entropy 1.2 * ****** (13.0 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel GCCGTAAA consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GYCGTAAA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:210001295-210001315 12 1.29e-05 CCTTGCTTTC GCCGTAAA G chr11:85339571-85339591 6 1.29e-05 GTTGA GCCGTAAA TCAGCAC chr2:7888944-7888964 9 1.29e-05 GCTCTGCA GCCGTAAA GTAC chr19:18434051-18434071 9 1.29e-05 GGACGAGA GCCGTAAA GTGC chr16:50781224-50781244 4 1.29e-05 AAG GCCGTAAA AGGAGTCAA chr3:141456842-141456862 3 1.29e-05 aa gccgtaaa gcaggacaca chr10:120514495-12051451 3 1.29e-05 CA GCCGTAAA GCAGCGGCGC chr1:86174123-86174143 3 1.29e-05 TC GCCGTAAA GCTACGCTTT chr16:70148162-70148182 1 1.29e-05 . GCCGTAAA GCGCGGAAGG chr1:77685120-77685140 13 1.29e-05 CGGAGGCAGT GCCGTAAA chr1:110091181-110091201 11 2.11e-05 CGCCGGAAGT GTCGTAAA CG chr20:5986685-5986705 2 2.11e-05 T GTCGTAAA AGCGTCGCGA chr4:6675743-6675763 11 2.11e-05 GACCGCAGGT GTCGTAAA AG chr7:149535465-149535485 3 2.94e-05 TG ACCGTAAA GCTGTTCGCT chr13:95248409-95248429 5 2.94e-05 TAGT ACCGTAAA GAGTATGG chr11:107328528-10732854 13 3.47e-05 ACTTGTTGCC ATCGTAAA chr6:113970605-113970625 6 5.53e-05 CTCAT GTCGTAAT TTCCCAG chr10:105127664-10512768 4 8.82e-05 GTT GTCGTGAA ATGCTCCTC chr17:80358868-80358888 6 8.82e-05 GTGCA GTCGTGAA AAAGGAA chr22:46525427-46525447 1 1.10e-04 . GTGGTAAA TGCGGAAATA chr6:112408716-112408736 5 1.30e-04 AGCT GCCGTAAG TCACGCTA chr19:48836387-48836407 11 1.78e-04 AAGTATAATA ACCGTAAT TG chr1:19372118-19372138 8 1.78e-04 tgtaaag gccgtaca tgtac chr12:25348255-25348275 9 1.78e-04 TCCGGCGT GCCGGAAA GTGC -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GYCGTAAA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:210001295-210001315 1.3e-05 11_[+1]_1 chr11:85339571-85339591 1.3e-05 5_[+1]_7 chr2:7888944-7888964 1.3e-05 8_[+1]_4 chr19:18434051-18434071 1.3e-05 8_[+1]_4 chr16:50781224-50781244 1.3e-05 3_[+1]_9 chr3:141456842-141456862 1.3e-05 2_[+1]_10 chr10:120514495-12051451 1.3e-05 2_[+1]_10 chr1:86174123-86174143 1.3e-05 2_[+1]_10 chr16:70148162-70148182 1.3e-05 [+1]_12 chr1:77685120-77685140 1.3e-05 12_[+1] chr1:110091181-110091201 2.1e-05 10_[+1]_2 chr20:5986685-5986705 2.1e-05 1_[+1]_11 chr4:6675743-6675763 2.1e-05 10_[+1]_2 chr7:149535465-149535485 2.9e-05 2_[+1]_10 chr13:95248409-95248429 2.9e-05 4_[+1]_8 chr11:107328528-10732854 3.5e-05 12_[+1] chr6:113970605-113970625 5.5e-05 5_[+1]_7 chr10:105127664-10512768 8.8e-05 3_[+1]_9 chr17:80358868-80358888 8.8e-05 5_[+1]_7 chr22:46525427-46525447 0.00011 [+1]_12 chr6:112408716-112408736 0.00013 4_[+1]_8 chr19:48836387-48836407 0.00018 10_[+1]_2 chr1:19372118-19372138 0.00018 7_[+1]_5 chr12:25348255-25348275 0.00018 8_[+1]_4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GYCGTAAA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF GYCGTAAA width=8 seqs=24 chr1:210001295-210001315 ( 12) GCCGTAAA 1 chr11:85339571-85339591 ( 6) GCCGTAAA 1 chr2:7888944-7888964 ( 9) GCCGTAAA 1 chr19:18434051-18434071 ( 9) GCCGTAAA 1 chr16:50781224-50781244 ( 4) GCCGTAAA 1 chr3:141456842-141456862 ( 3) GCCGTAAA 1 chr10:120514495-12051451 ( 3) GCCGTAAA 1 chr1:86174123-86174143 ( 3) GCCGTAAA 1 chr16:70148162-70148182 ( 1) GCCGTAAA 1 chr1:77685120-77685140 ( 13) GCCGTAAA 1 chr1:110091181-110091201 ( 11) GTCGTAAA 1 chr20:5986685-5986705 ( 2) GTCGTAAA 1 chr4:6675743-6675763 ( 11) GTCGTAAA 1 chr7:149535465-149535485 ( 3) ACCGTAAA 1 chr13:95248409-95248429 ( 5) ACCGTAAA 1 chr11:107328528-10732854 ( 13) ATCGTAAA 1 chr6:113970605-113970625 ( 6) GTCGTAAT 1 chr10:105127664-10512768 ( 4) GTCGTGAA 1 chr17:80358868-80358888 ( 6) GTCGTGAA 1 chr22:46525427-46525447 ( 1) GTGGTAAA 1 chr6:112408716-112408736 ( 5) GCCGTAAG 1 chr19:48836387-48836407 ( 11) ACCGTAAT 1 chr1:19372118-19372138 ( 8) GCCGTACA 1 chr12:25348255-25348275 ( 9) GCCGGAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GYCGTAAA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 7.52089 E= 6.7e-020 -25 -1123 144 -1123 -1123 115 -1123 79 -1123 167 -288 -1123 -1123 -1123 170 -1123 -1123 -1123 -288 231 221 -1123 -188 -1123 227 -285 -1123 -1123 214 -1123 -288 -121 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GYCGTAAA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 24 E= 6.7e-020 0.166667 0.000000 0.833333 0.000000 0.000000 0.666667 0.000000 0.333333 0.000000 0.958333 0.041667 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.041667 0.958333 0.916667 0.000000 0.083333 0.000000 0.958333 0.041667 0.000000 0.000000 0.875000 0.000000 0.041667 0.083333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif GYCGTAAA MEME-1 regular expression -------------------------------------------------------------------------------- G[CT]CGTAAA -------------------------------------------------------------------------------- Time 2.59 secs. ******************************************************************************** ******************************************************************************** MOTIF TTTACGRC MEME-2 width = 8 sites = 24 llr = 205 E-value = 1.1e-014 ******************************************************************************** -------------------------------------------------------------------------------- Motif TTTACGRC MEME-2 Description -------------------------------------------------------------------------------- Simplified A :::7:14: pos.-specific C ::11a::9 probability G :::2:96: matrix T aa9::::: bits 2.4 * 2.1 ** 1.9 ** 1.7 *** * Relative 1.4 *** ** Entropy 1.2 *** ** * (12.3 bits) 0.9 *** **** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel TTTACGGC consensus A sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTACGRC MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:101491393-101491413 4 7.86e-06 CAC TTTACGAC TAGCGGGAG chr15:43398296-43398316 13 7.86e-06 GGACGACACT TTTACGAC chr1:714279-714299 9 7.86e-06 GGAGGAGC TTTACGAC TTCC chr1:154245044-154245064 13 7.86e-06 CTTACCGTCG TTTACGAC chr1:220220026-220220046 6 7.86e-06 GGGAC TTTACGAC ACTTCGT chr6:58313024-58313044 11 2.01e-05 AGTAGCCACA TTTACGGC AG chr10:75007085-75007105 9 2.01e-05 ATCCGCGC TTTACGGC GGCC chr5:140079993-140080013 12 2.01e-05 CAAGCCGCTT TTTACGGC G chr7:22862481-22862501 13 2.01e-05 ACACACGGCC TTTACGGC chr14:57857288-57857308 13 2.01e-05 GCTGAGGCGC TTTACGGC chr1:89149904-89149924 4 3.23e-05 GCT TTTGCGAC GCGGTGACA chr4:6711612-6711632 7 5.14e-05 GGCCTT TTTGCGGC CCTTTC chr19:46850339-46850359 7 5.14e-05 GGTCGC TTTGCGGC ATGGCG chr5:96518970-96518990 8 7.62e-05 TAAGCGC TTTACAGC GCCAG chr4:159593493-159593513 9 9.48e-05 GTTCTTGC TTTCCGGC AGGT chr1:160232300-160232320 2 9.48e-05 C TTTCCGGC CCCGTTTGCG chr12:88535884-88535904 11 1.07e-04 GAGCCTACAG TTCACGAC CG chr1:87380032-87380052 9 1.07e-04 TTCTTTTA TTCACGAC ACTT chr14:96828498-96828518 5 1.36e-04 TGCT TTTACGAT CTGTCACG chr1:249120440-249120460 7 1.60e-04 TCTTGC TTTACGGA GCTGCG chr3:99979820-99979840 11 1.72e-04 CCGGATCCAC TTTTCGGC AA chr19:3557728-3557748 7 1.84e-04 TCCGCC TCTACGAC GGGCGC chr1:161068114-161068134 11 2.23e-04 CGACCTTCGG TTTGCAGC GG chr11:66050071-66050091 3 4.07e-04 GC TTCCCGGC CGTGCCGACA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTACGRC MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:101491393-101491413 7.9e-06 3_[+2]_9 chr15:43398296-43398316 7.9e-06 12_[+2] chr1:714279-714299 7.9e-06 8_[+2]_4 chr1:154245044-154245064 7.9e-06 12_[+2] chr1:220220026-220220046 7.9e-06 5_[+2]_7 chr6:58313024-58313044 2e-05 10_[+2]_2 chr10:75007085-75007105 2e-05 8_[+2]_4 chr5:140079993-140080013 2e-05 11_[+2]_1 chr7:22862481-22862501 2e-05 12_[+2] chr14:57857288-57857308 2e-05 12_[+2] chr1:89149904-89149924 3.2e-05 3_[+2]_9 chr4:6711612-6711632 5.1e-05 6_[+2]_6 chr19:46850339-46850359 5.1e-05 6_[+2]_6 chr5:96518970-96518990 7.6e-05 7_[+2]_5 chr4:159593493-159593513 9.5e-05 8_[+2]_4 chr1:160232300-160232320 9.5e-05 1_[+2]_11 chr12:88535884-88535904 0.00011 10_[+2]_2 chr1:87380032-87380052 0.00011 8_[+2]_4 chr14:96828498-96828518 0.00014 4_[+2]_8 chr1:249120440-249120460 0.00016 6_[+2]_6 chr3:99979820-99979840 0.00017 10_[+2]_2 chr19:3557728-3557748 0.00018 6_[+2]_6 chr1:161068114-161068134 0.00022 10_[+2]_2 chr11:66050071-66050091 0.00041 2_[+2]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTACGRC MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TTTACGRC width=8 seqs=24 chr1:101491393-101491413 ( 4) TTTACGAC 1 chr15:43398296-43398316 ( 13) TTTACGAC 1 chr1:714279-714299 ( 9) TTTACGAC 1 chr1:154245044-154245064 ( 13) TTTACGAC 1 chr1:220220026-220220046 ( 6) TTTACGAC 1 chr6:58313024-58313044 ( 11) TTTACGGC 1 chr10:75007085-75007105 ( 9) TTTACGGC 1 chr5:140079993-140080013 ( 12) TTTACGGC 1 chr7:22862481-22862501 ( 13) TTTACGGC 1 chr14:57857288-57857308 ( 13) TTTACGGC 1 chr1:89149904-89149924 ( 4) TTTGCGAC 1 chr4:6711612-6711632 ( 7) TTTGCGGC 1 chr19:46850339-46850359 ( 7) TTTGCGGC 1 chr5:96518970-96518990 ( 8) TTTACAGC 1 chr4:159593493-159593513 ( 9) TTTCCGGC 1 chr1:160232300-160232320 ( 2) TTTCCGGC 1 chr12:88535884-88535904 ( 11) TTCACGAC 1 chr1:87380032-87380052 ( 9) TTCACGAC 1 chr14:96828498-96828518 ( 5) TTTACGAT 1 chr1:249120440-249120460 ( 7) TTTACGGA 1 chr3:99979820-99979840 ( 11) TTTTCGGC 1 chr19:3557728-3557748 ( 7) TCTACGAC 1 chr1:161068114-161068134 ( 11) TTTGCAGC 1 chr11:66050071-66050091 ( 3) TTCCCGGC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTACGRC MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.66267 E= 1.1e-014 -1123 -1123 -1123 237 -1123 -285 -1123 231 -1123 -127 -1123 218 175 -127 -88 -221 -1123 173 -1123 -1123 -125 -1123 157 -1123 107 -1123 92 -1123 -225 161 -1123 -221 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTACGRC MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 24 E= 1.1e-014 0.000000 0.000000 0.000000 1.000000 0.000000 0.041667 0.000000 0.958333 0.000000 0.125000 0.000000 0.875000 0.666667 0.125000 0.166667 0.041667 0.000000 1.000000 0.000000 0.000000 0.083333 0.000000 0.916667 0.000000 0.416667 0.000000 0.583333 0.000000 0.041667 0.916667 0.000000 0.041667 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TTTACGRC MEME-2 regular expression -------------------------------------------------------------------------------- TTTACG[GA]C -------------------------------------------------------------------------------- Time 3.51 secs. ******************************************************************************** ******************************************************************************** MOTIF CTTCCGGK MEME-3 width = 8 sites = 11 llr = 97 E-value = 3.4e+001 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTTCCGGK MEME-3 Description -------------------------------------------------------------------------------- Simplified A :::::1:2 pos.-specific C a::aa:3: probability G :::::975 matrix T :aa::::3 bits 2.4 ** 2.1 ** 1.9 ** 1.7 ***** Relative 1.4 ****** Entropy 1.2 ****** (12.7 bits) 0.9 ******* 0.7 ******* 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CTTCCGGG consensus CT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGK MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr12:64616054-64616074 11 2.97e-05 CGGCCTCGCA CTTCCGGG TT chr19:2622725-2622745 8 2.97e-05 AGGGAGG CTTCCGGG ATGGG chr9:127962760-127962780 10 2.97e-05 CCGGACGCT CTTCCGGG TCC chr5:93447354-93447374 1 2.97e-05 . CTTCCGGG GTCTTCAGGA chr7:72722836-72722856 11 2.97e-05 CCCGCCCGGA CTTCCGGG GT chr8:66864012-66864032 7 4.83e-05 CCTTTC CTTCCGGT GCAGCA chr17:4634719-4634739 5 6.74e-05 GCCA CTTCCGGA ACAAGCGT chr16:74402122-74402142 5 9.64e-05 CGAC CTTCCGCG CTTTACGG chr10:97890044-97890064 1 1.15e-04 . CTTCCGCT TAACTTGCCG chr16:15736999-15737019 6 1.33e-04 ttccg cttccgca ccgcacc chr17:41322461-41322481 11 1.64e-04 CGCCTCTACG CTTCCAGT TG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGK MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr12:64616054-64616074 3e-05 10_[+3]_2 chr19:2622725-2622745 3e-05 7_[+3]_5 chr9:127962760-127962780 3e-05 9_[+3]_3 chr5:93447354-93447374 3e-05 [+3]_12 chr7:72722836-72722856 3e-05 10_[+3]_2 chr8:66864012-66864032 4.8e-05 6_[+3]_6 chr17:4634719-4634739 6.7e-05 4_[+3]_8 chr16:74402122-74402142 9.6e-05 4_[+3]_8 chr10:97890044-97890064 0.00011 [+3]_12 chr16:15736999-15737019 0.00013 5_[+3]_7 chr17:41322461-41322481 0.00016 10_[+3]_2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGK MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTTCCGGK width=8 seqs=11 chr12:64616054-64616074 ( 11) CTTCCGGG 1 chr19:2622725-2622745 ( 8) CTTCCGGG 1 chr9:127962760-127962780 ( 10) CTTCCGGG 1 chr5:93447354-93447374 ( 1) CTTCCGGG 1 chr7:72722836-72722856 ( 11) CTTCCGGG 1 chr8:66864012-66864032 ( 7) CTTCCGGT 1 chr17:4634719-4634739 ( 5) CTTCCGGA 1 chr16:74402122-74402142 ( 5) CTTCCGCG 1 chr10:97890044-97890064 ( 1) CTTCCGCT 1 chr16:15736999-15737019 ( 6) CTTCCGCA 1 chr17:41322461-41322481 ( 11) CTTCCAGT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGK MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 7.75266 E= 3.4e+001 -1010 173 -1010 -1010 -1010 -1010 -1010 237 -1010 -1010 -1010 237 -1010 173 -1010 -1010 -1010 173 -1010 -1010 -112 -1010 156 -1010 -1010 -14 124 -1010 -13 -1010 83 50 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGK MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 11 E= 3.4e+001 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.090909 0.000000 0.909091 0.000000 0.000000 0.272727 0.727273 0.000000 0.181818 0.000000 0.545455 0.272727 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTTCCGGK MEME-3 regular expression -------------------------------------------------------------------------------- CTTCCG[GC][GT] -------------------------------------------------------------------------------- Time 4.26 secs. ******************************************************************************** ******************************************************************************** MOTIF CMHTTTAC MEME-4 width = 8 sites = 5 llr = 51 E-value = 9.2e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CMHTTTAC MEME-4 Description -------------------------------------------------------------------------------- Simplified A :62:::a: pos.-specific C a44::::a probability G :::::::: matrix T ::4aaa:: bits 2.4 **** 2.1 **** 1.9 **** 1.7 * ***** Relative 1.4 * ***** Entropy 1.2 ** ***** (14.6 bits) 0.9 ** ***** 0.7 ** ***** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel CACTTTAC consensus CT sequence A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMHTTTAC MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr16:85833176-85833196 13 4.93e-06 CCCGGCCCGG CATTTTAC chr3:52719991-52720011 11 1.26e-05 GGCGGTGACG CACTTTAC GG chr14:21134779-21134799 5 1.77e-05 gtac caatttac tgtattag chr22:20307616-20307636 13 2.52e-05 CGCTCCGCCC CCTTTTAC chr19:39109757-39109777 11 3.68e-05 TAGAGCCTTT CCCTTTAC CG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMHTTTAC MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:85833176-85833196 4.9e-06 12_[+4] chr3:52719991-52720011 1.3e-05 10_[+4]_2 chr14:21134779-21134799 1.8e-05 4_[+4]_8 chr22:20307616-20307636 2.5e-05 12_[+4] chr19:39109757-39109777 3.7e-05 10_[+4]_2 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMHTTTAC MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CMHTTTAC width=8 seqs=5 chr16:85833176-85833196 ( 13) CATTTTAC 1 chr3:52719991-52720011 ( 11) CACTTTAC 1 chr14:21134779-21134799 ( 5) CAATTTAC 1 chr22:20307616-20307636 ( 13) CCTTTTAC 1 chr19:39109757-39109777 ( 11) CCCTTTAC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMHTTTAC MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.77541 E= 9.2e+002 -897 173 -897 -897 159 41 -897 -897 1 41 -897 105 -897 -897 -897 237 -897 -897 -897 237 -897 -897 -897 237 233 -897 -897 -897 -897 173 -897 -897 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMHTTTAC MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 5 E= 9.2e+002 0.000000 1.000000 0.000000 0.000000 0.600000 0.400000 0.000000 0.000000 0.200000 0.400000 0.000000 0.400000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CMHTTTAC MEME-4 regular expression -------------------------------------------------------------------------------- C[AC][CTA]TTTAC -------------------------------------------------------------------------------- Time 5.06 secs. ******************************************************************************** ******************************************************************************** MOTIF MTTGCTTT MEME-5 width = 8 sites = 2 llr = 23 E-value = 4.3e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif MTTGCTTT MEME-5 Description -------------------------------------------------------------------------------- Simplified A 5::::::: pos.-specific C 5:::a::: probability G :::a:::: matrix T :aa::aaa bits 2.4 ** *** 2.1 ** *** 1.9 ** *** 1.7 ******* Relative 1.4 ******* Entropy 1.2 ******* (16.3 bits) 0.9 ******** 0.7 ******** 0.5 ******** 0.2 ******** 0.0 -------- Multilevel ATTGCTTT consensus C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTTGCTTT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chrX:129040099-129040119 10 4.92e-06 GAAACAGAA ATTGCTTT GCG chr1:210001295-210001315 3 1.24e-05 AC CTTGCTTT CGCCGTAAAG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTTGCTTT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chrX:129040099-129040119 4.9e-06 9_[+5]_3 chr1:210001295-210001315 1.2e-05 2_[+5]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTTGCTTT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF MTTGCTTT width=8 seqs=2 chrX:129040099-129040119 ( 10) ATTGCTTT 1 chr1:210001295-210001315 ( 3) CTTGCTTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTTGCTTT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 10.6653 E= 4.3e+003 133 73 -765 -765 -765 -765 -765 237 -765 -765 -765 237 -765 -765 170 -765 -765 173 -765 -765 -765 -765 -765 237 -765 -765 -765 237 -765 -765 -765 237 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTTGCTTT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 4.3e+003 0.500000 0.500000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTTGCTTT MEME-5 regular expression -------------------------------------------------------------------------------- [AC]TTGCTTT -------------------------------------------------------------------------------- Time 5.77 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr14:57857288-57857308 5.68e-05 12_[+2(2.01e-05)] chr17:7232835-7232855 8.81e-01 20 chr22:20307616-20307636 1.60e-02 12_[+4(2.52e-05)] chrX:119737854-119737874 3.13e-01 20 chrX:153639820-153639840 3.81e-02 20 chr1:11986514-11986534 8.80e-01 20 chr19:46850339-46850359 2.16e-04 6_[+2(5.14e-05)]_6 chr15:59279909-59279929 9.99e-01 20 chr17:79519487-79519507 5.67e-01 20 chr1:111682857-111682877 9.28e-01 20 chr1:92949478-92949498 2.83e-01 20 chr9:108320391-108320411 6.86e-02 20 chr10:75173105-75173125 8.96e-01 20 chr4:87855910-87855930 9.92e-01 20 chr10:31607938-31607958 6.49e-01 20 chr2:120436770-120436790 3.56e-01 20 chr1:161068114-161068134 3.10e-03 20 chr20:247662-247682 4.38e-01 20 chr1:39491974-39491994 8.36e-01 20 chr1:77685120-77685140 1.74e-02 12_[+1(1.29e-05)] chr16:74402122-74402142 1.02e-04 4_[+3(9.64e-05)]_8 chr16:67143851-67143871 8.99e-01 20 chr16:70148162-70148182 4.57e-02 [+1(1.29e-05)]_12 chrX:129040099-129040119 6.41e-03 9_[+5(4.92e-06)]_3 chr3:196019352-196019372 1.02e-01 20 chr2:101869366-101869386 9.99e-01 20 chr1:15943781-15943801 5.42e-01 20 chr15:72410754-72410774 9.65e-01 20 chr9:115983556-115983576 1.81e-01 20 chr3:12525956-12525976 7.62e-01 20 chr7:155437158-155437178 7.04e-01 20 chr16:47495044-47495064 9.04e-01 20 chr18:54318505-54318525 6.39e-01 20 chr6:112408716-112408736 2.03e-02 20 chr3:180707505-180707525 2.46e-01 20 chr15:52263959-52263979 4.41e-01 20 chr6:166796548-166796568 9.77e-01 20 chr16:15736999-15737019 2.62e-02 20 chr4:6711612-6711632 2.82e-03 6_[+2(5.14e-05)]_6 chr4:142142079-142142099 1.48e-01 20 chr20:36322398-36322418 3.42e-01 20 chr1:220220026-220220046 1.37e-04 5_[+2(7.86e-06)]_7 chr12:48577356-48577376 4.38e-02 20 chr1:38388586-38388606 7.31e-01 20 chr14:96828498-96828518 1.38e-03 20 chr1:86174123-86174143 4.56e-03 2_[+1(1.29e-05)]_10 chr1:171750379-171750399 4.96e-02 20 chr6:119214777-119214797 1.80e-02 20 chr4:6675743-6675763 4.43e-02 10_[+1(2.11e-05)]_2 chr17:4046351-4046371 7.36e-01 20 chr2:128568430-128568450 9.94e-01 20 chr10:120514495-12051451 3.23e-02 2_[+1(1.29e-05)]_10 chr8:86019286-86019306 6.41e-01 20 chr16:58888494-58888514 1.03e-01 20 chr2:85788696-85788716 9.81e-01 20 chr20:5986685-5986705 1.88e-02 1_[+1(2.11e-05)]_11 chr15:101142624-10114264 9.99e-01 20 chr13:80055247-80055267 4.09e-01 20 chrX:153640023-153640043 7.46e-01 20 chr14:36278522-36278542 3.91e-01 20 chr7:107531475-107531495 4.33e-01 20 chr1:231473691-231473711 4.27e-01 20 chr13:26828101-26828121 9.52e-02 20 chr1:53686203-53686223 4.43e-01 20 chr1:160232300-160232320 2.54e-03 1_[+2(9.48e-05)]_11 chr10:70748514-70748534 3.69e-01 20 chr12:25348255-25348275 7.07e-02 20 chr4:6642367-6642387 8.42e-01 20 chr8:41348035-41348055 9.58e-01 20 chr20:30135129-30135149 1.21e-01 20 chr2:241500610-241500630 5.34e-01 20 chr14:21134779-21134799 4.66e-04 4_[+4(1.77e-05)]_8 chr19:7745772-7745792 9.23e-01 20 chr6:107780796-107780816 4.95e-01 20 chr10:38691676-38691696 8.33e-01 20 chr11:111896049-11189606 9.84e-01 20 chr7:22862481-22862501 3.68e-04 12_[+2(2.01e-05)] chr6:6657842-6657862 5.29e-01 20 chr1:154245044-154245064 3.88e-05 12_[+2(7.86e-06)] chr5:110848393-110848413 8.76e-01 20 chrX:135578943-135578963 9.90e-01 20 chr9:7799780-7799800 2.97e-01 20 chr19:52552062-52552082 2.71e-01 20 chr22:42177252-42177272 9.94e-01 20 chr14:104028797-10402881 9.70e-01 20 chr16:85833176-85833196 3.29e-03 12_[+4(4.93e-06)] chr12:53400053-53400073 3.88e-01 20 chr3:99979820-99979840 1.20e-03 20 chr2:74191036-74191056 2.38e-01 20 chr11:64795141-64795161 9.87e-01 20 chr17:73127963-73127983 4.95e-01 20 chr8:66864012-66864032 4.88e-04 6_[+3(4.83e-05)]_6 chr17:80408673-80408693 9.51e-01 20 chr7:72722836-72722856 1.45e-02 10_[+3(2.97e-05)]_2 chr1:19372118-19372138 5.13e-02 20 chr3:127309658-127309678 9.33e-01 20 chr1:714279-714299 2.65e-04 8_[+2(7.86e-06)]_4 chr1:224180521-224180541 3.20e-01 20 chr15:43398296-43398316 1.71e-04 12_[+2(7.86e-06)] chr17:4699388-4699408 4.67e-01 20 chr4:6717838-6717858 8.28e-01 20 chr2:32264876-32264896 3.12e-01 20 chr6:113970605-113970625 1.46e-03 5_[+1(5.53e-05)]_7 chr2:114341612-114341632 8.41e-01 20 chr8:33370679-33370699 1.64e-01 20 chr1:87380032-87380052 4.42e-03 20 chr11:107328528-10732854 5.47e-03 12_[+1(3.47e-05)] chr5:93447354-93447374 1.56e-02 [+3(2.97e-05)]_12 chr19:53360810-53360830 9.18e-01 20 chr16:69760415-69760435 8.56e-01 20 chr6:31670887-31670907 6.50e-02 20 chr2:149402962-149402982 5.18e-02 20 chr7:5271947-5271967 7.23e-01 20 chr3:141456842-141456862 4.84e-02 2_[+1(1.29e-05)]_10 chr16:50781224-50781244 4.47e-02 3_[+1(1.29e-05)]_9 chr17:80358868-80358888 1.51e-01 5_[+1(8.82e-05)]_7 chr16:284587-284607 9.93e-01 20 chr2:172778765-172778785 8.80e-01 20 chr16:31084622-31084642 9.96e-01 20 chr5:180616843-180616863 9.64e-01 20 chr4:123843237-123843257 8.60e-01 20 chr5:96518970-96518990 8.25e-05 7_[+2(7.62e-05)]_5 chr1:101491393-101491413 5.40e-06 3_[+2(7.86e-06)]_9 chr19:48836387-48836407 1.47e-01 20 chr11:85956156-85956176 9.68e-01 20 chr19:38865426-38865446 7.42e-01 20 chr14:104029340-10402936 6.17e-02 20 chr11:66050071-66050091 3.77e-03 20 chr3:129158828-129158848 5.67e-01 20 chr11:43665777-43665797 8.40e-02 20 chr1:22109638-22109658 9.71e-01 20 chr19:18263453-18263473 4.10e-02 20 chr4:88343744-88343764 4.63e-01 20 chr17:41322461-41322481 6.29e-03 20 chr19:53073588-53073608 1.34e-01 20 chr9:127962760-127962780 1.07e-02 9_[+3(2.97e-05)]_3 chr19:18434051-18434071 3.95e-02 8_[+1(1.29e-05)]_4 chr19:2622725-2622745 8.45e-03 7_[+3(2.97e-05)]_5 chr12:30848820-30848840 1.00e+00 20 chr10:130262798-13026281 6.64e-01 20 chr2:7888944-7888964 1.25e-03 8_[+1(1.29e-05)]_4 chr3:52719991-52720011 2.53e-03 10_[+4(1.26e-05)]_2 chr8:92082277-92082297 6.69e-01 20 chr14:24036952-24036972 6.03e-01 20 chr3:133292012-133292032 4.27e-01 20 chr1:56798025-56798045 9.06e-01 20 chr4:166248674-166248694 9.22e-01 20 chr6:43968302-43968322 9.94e-01 20 chr11:207586-207606 6.08e-01 20 chr5:140079993-140080013 4.54e-05 11_[+2(2.01e-05)]_1 chr10:75007085-75007105 3.36e-05 8_[+2(2.01e-05)]_4 chr15:40615702-40615722 6.19e-02 20 chr10:106098388-10609840 9.39e-01 20 chr10:105127664-10512768 6.20e-02 3_[+1(8.82e-05)]_9 chr19:38865625-38865645 3.59e-01 20 chr17:40346537-40346557 9.29e-01 20 chr1:89149904-89149924 7.53e-04 3_[+2(3.23e-05)]_9 chr19:53898429-53898449 8.03e-01 20 chr11:85339571-85339591 4.07e-02 5_[+1(1.29e-05)]_7 chr19:41082739-41082759 8.56e-01 20 chr14:60558778-60558798 8.60e-01 20 chr12:106696431-10669645 6.49e-01 20 chr20:47131937-47131957 1.13e-01 20 chr2:65584897-65584917 4.33e-04 7_[+5(3.59e-05)]_5 chr16:89392600-89392620 9.98e-01 20 chr22:42228959-42228979 8.84e-01 20 chr4:6676389-6676409 1.18e-01 20 chr10:105881882-10588190 8.05e-02 20 chr2:172544022-172544042 6.11e-01 20 chr1:234659471-234659491 9.91e-01 20 chr1:2480309-2480329 5.59e-02 20 chr2:27440305-27440325 3.69e-01 20 chr12:64616054-64616074 5.89e-03 10_[+3(2.97e-05)]_2 chr19:39926638-39926658 4.00e-01 20 chr19:41284131-41284151 9.62e-01 20 chr13:95248409-95248429 4.53e-02 4_[+1(2.94e-05)]_8 chr6:24721572-24721592 7.82e-01 20 chr17:4901049-4901069 2.94e-01 20 chr10:1094952-1094972 3.11e-01 20 chr1:231376910-231376930 5.67e-02 20 chr1:115642182-115642202 2.50e-01 20 chr12:50794484-50794504 7.41e-01 20 chr1:249120440-249120460 4.79e-06 1_[+5(1.24e-05)]_11 chr8:55047702-55047722 1.99e-01 20 chr7:149535465-149535485 1.93e-02 2_[+1(2.94e-05)]_10 chr22:47130977-47130997 1.00e+00 20 chr22:46525427-46525447 1.00e-01 20 chr19:49141153-49141173 5.47e-01 20 chr16:77225016-77225036 4.10e-02 20 chr16:88877888-88877908 9.12e-01 20 chr16:15068758-15068778 1.62e-01 20 chr4:159593493-159593513 1.28e-05 3_[+5(1.24e-05)]_9 chr11:47869663-47869683 9.93e-01 20 chr1:111991959-111991979 5.91e-01 20 chr7:98923505-98923525 6.30e-01 20 chr8:126010593-126010613 2.64e-01 20 chr8:22526631-22526651 3.24e-01 20 chr18:3261895-3261915 8.24e-01 20 chr2:122407266-122407286 9.36e-02 20 chr3:119419506-119419526 3.93e-01 20 chr4:110736666-110736686 3.63e-01 20 chr19:39109757-39109777 3.74e-03 10_[+4(3.68e-05)]_2 chr6:58313024-58313044 1.17e-03 10_[+2(2.01e-05)]_2 chr10:74091912-74091932 7.88e-01 20 chr1:24104981-24105001 9.40e-01 20 chr12:108908952-10890897 6.69e-01 20 chr1:210001295-210001315 2.29e-06 2_[+5(1.24e-05)]_1_[+1(1.29e-05)]_1 chr10:97890044-97890064 3.66e-03 20 chr10:103892377-10389239 9.55e-01 20 chr1:235324557-235324577 6.46e-01 20 chr2:203776617-203776637 2.07e-01 20 chr20:60982595-60982615 2.92e-03 20 chr13:76112101-76112121 1.93e-01 20 chr18:12991229-12991249 6.54e-01 20 chr16:10480836-10480856 6.50e-02 20 chr19:58912809-58912829 5.06e-01 20 chr10:112201617-11220163 6.50e-01 20 chr6:31671088-31671108 5.33e-01 20 chr1:110026866-110026886 1.37e-01 20 chr22:18560641-18560661 7.09e-01 20 chr17:56296585-56296605 4.27e-01 20 chr4:159731499-159731519 7.51e-01 20 chr5:43313815-43313835 6.36e-01 20 chr16:4475531-4475551 9.88e-01 20 chr14:21979566-21979586 5.19e-01 20 chr20:32890895-32890915 1.03e-02 20 chr9:101018204-101018224 6.57e-01 20 chr9:100807871-100807891 2.67e-01 20 chr4:4526308-4526328 2.56e-01 20 chr3:49131807-49131827 9.15e-01 20 chr9:19103045-19103065 5.34e-01 20 chr1:109618712-109618732 4.24e-01 20 chr17:8093565-8093585 3.96e-01 20 chr17:7589684-7589704 5.19e-02 20 chr22:18484480-18484500 4.66e-01 20 chr17:80551004-80551024 5.13e-01 20 chr11:114271330-11427135 8.49e-01 20 chr19:1940890-1940910 8.92e-01 20 chr14:60715665-60715685 1.49e-01 20 chr17:27046734-27046754 7.07e-01 20 chr7:21985668-21985688 6.33e-01 20 chr19:3557728-3557748 1.86e-02 20 chr19:36704952-36704972 2.76e-02 20 chr12:88535884-88535904 3.42e-03 20 chr18:23670749-23670769 4.40e-02 20 chr1:42928807-42928827 8.73e-01 20 chr10:97889824-97889844 9.34e-01 20 chr15:55611359-55611379 3.80e-01 20 chr17:4634719-4634739 5.71e-03 4_[+3(6.74e-05)]_8 chr1:110091181-110091201 4.44e-02 10_[+1(2.11e-05)]_2 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c22n05.farnam.hpc.yale.internal ********************************************************************************