******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/CBFB.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr19:8634153-8634173 1.0000 20 chr9:123605277-123605297 1.0000 20 chr3:72226980-72227000 1.0000 20 chr1:165362452-165362472 1.0000 20 chr2:152907627-152907647 1.0000 20 chr12:49351329-49351349 1.0000 20 chr11:13484844-13484864 1.0000 20 chr11:7597512-7597532 1.0000 20 chr16:57451081-57451101 1.0000 20 chr9:138831385-138831405 1.0000 20 chr11:120215243-12021526 1.0000 20 chr5:141397815-141397835 1.0000 20 chr20:62199351-62199371 1.0000 20 chr2:240189291-240189311 1.0000 20 chr7:91763155-91763175 1.0000 20 chr19:46149465-46149485 1.0000 20 chr7:5371148-5371168 1.0000 20 chr15:100259354-10025937 1.0000 20 chr8:56901965-56901985 1.0000 20 chr1:232941102-232941122 1.0000 20 chr15:70772729-70772749 1.0000 20 chr12:10396619-10396639 1.0000 20 chr17:4167292-4167312 1.0000 20 chr10:125532692-12553271 1.0000 20 chr8:142046324-142046344 1.0000 20 chr3:56759449-56759469 1.0000 20 chr3:71276186-71276206 1.0000 20 chr18:44472978-44472998 1.0000 20 chr17:53046053-53046073 1.0000 20 chr10:51565168-51565188 1.0000 20 chr2:228473515-228473535 1.0000 20 chr1:101406886-101406906 1.0000 20 chr1:31342086-31342106 1.0000 20 chr11:123355357-12335537 1.0000 20 chr16:68390503-68390523 1.0000 20 chr16:30672171-30672191 1.0000 20 chr10:121073401-12107342 1.0000 20 chr2:242383446-242383466 1.0000 20 chr11:125757514-12575753 1.0000 20 chr21:36238031-36238051 1.0000 20 chr9:116341365-116341385 1.0000 20 chr10:90595547-90595567 1.0000 20 chr9:15511373-15511393 1.0000 20 chr1:23039058-23039078 1.0000 20 chr3:56929005-56929025 1.0000 20 chr3:49131526-49131546 1.0000 20 chr4:15683254-15683274 1.0000 20 chr16:81865496-81865516 1.0000 20 chr11:191644-191664 1.0000 20 chr9:102029026-102029046 1.0000 20 chr8:98650874-98650894 1.0000 20 chr3:72150019-72150039 1.0000 20 chr15:40347064-40347084 1.0000 20 chr4:186086870-186086890 1.0000 20 chr15:59949657-59949677 1.0000 20 chr1:28496025-28496045 1.0000 20 chr7:35749232-35749252 1.0000 20 chr7:129791673-129791693 1.0000 20 chr14:51342238-51342258 1.0000 20 chr17:65370917-65370937 1.0000 20 chr19:5139400-5139420 1.0000 20 chr17:61776774-61776794 1.0000 20 chr6:44355268-44355288 1.0000 20 chr22:42000176-42000196 1.0000 20 chr19:47291790-47291810 1.0000 20 chr10:75118557-75118577 1.0000 20 chr4:83214623-83214643 1.0000 20 chr12:53599726-53599746 1.0000 20 chr3:185869124-185869144 1.0000 20 chr1:183002530-183002550 1.0000 20 chr3:189807702-189807722 1.0000 20 chrX:41193428-41193448 1.0000 20 chr2:62541164-62541184 1.0000 20 chr6:30919819-30919839 1.0000 20 chr3:105086884-105086904 1.0000 20 chr6:10534113-10534133 1.0000 20 chr22:17568767-17568787 1.0000 20 chr2:69875440-69875460 1.0000 20 chr17:9292568-9292588 1.0000 20 chr22:30838594-30838614 1.0000 20 chr11:70270402-70270422 1.0000 20 chr6:32054630-32054650 1.0000 20 chr16:87812864-87812884 1.0000 20 chr1:17222706-17222726 1.0000 20 chr14:65676941-65676961 1.0000 20 chr6:86388406-86388426 1.0000 20 chr17:7760908-7760928 1.0000 20 chr9:98637902-98637922 1.0000 20 chr17:4843562-4843582 1.0000 20 chr1:167905779-167905799 1.0000 20 chr3:40226722-40226742 1.0000 20 chr18:57588732-57588752 1.0000 20 chr22:29225507-29225527 1.0000 20 chr10:1140426-1140446 1.0000 20 chr1:205255872-205255892 1.0000 20 chr4:38732881-38732901 1.0000 20 chr6:43603581-43603601 1.0000 20 chr5:180230996-180231016 1.0000 20 chr6:97731122-97731142 1.0000 20 chr22:22385398-22385418 1.0000 20 chr6:391788-391808 1.0000 20 chr6:17600552-17600572 1.0000 20 chr3:191047080-191047100 1.0000 20 chr15:45019400-45019420 1.0000 20 chr1:221886657-221886677 1.0000 20 chr15:66649015-66649035 1.0000 20 chr2:204463208-204463228 1.0000 20 chr14:31677597-31677617 1.0000 20 chr15:22833402-22833422 1.0000 20 chr20:10653391-10653411 1.0000 20 chr15:70755662-70755682 1.0000 20 chr17:56525034-56525054 1.0000 20 chr11:118187478-11818749 1.0000 20 chrX:99881055-99881075 1.0000 20 chr3:149198335-149198355 1.0000 20 chr6:148525356-148525376 1.0000 20 chr6:5567742-5567762 1.0000 20 chr15:51369451-51369471 1.0000 20 chr14:88472786-88472806 1.0000 20 chr1:44116174-44116194 1.0000 20 chr1:182573471-182573491 1.0000 20 chr20:37433800-37433820 1.0000 20 chr5:66502933-66502953 1.0000 20 chr2:160568953-160568973 1.0000 20 chr11:14786926-14786946 1.0000 20 chr11:35167008-35167028 1.0000 20 chr6:16504336-16504356 1.0000 20 chr4:17812540-17812560 1.0000 20 chr17:18967127-18967147 1.0000 20 chr2:88315936-88315956 1.0000 20 chr16:4817272-4817292 1.0000 20 chr11:73372135-73372155 1.0000 20 chr8:125538970-125538990 1.0000 20 chr1:17223037-17223057 1.0000 20 chr11:6424074-6424094 1.0000 20 chr9:6413130-6413150 1.0000 20 chr21:45378498-45378518 1.0000 20 chr2:219773807-219773827 1.0000 20 chr6:43693061-43693081 1.0000 20 chr13:21750758-21750778 1.0000 20 chr15:85197545-85197565 1.0000 20 chr21:34084524-34084544 1.0000 20 chr1:161039733-161039753 1.0000 20 chr3:141217824-141217844 1.0000 20 chr1:172715589-172715609 1.0000 20 chr8:142012428-142012448 1.0000 20 chr10:21991950-21991970 1.0000 20 chr10:90145506-90145526 1.0000 20 chr17:56698677-56698697 1.0000 20 chr1:200177117-200177137 1.0000 20 chr2:68666153-68666173 1.0000 20 chr11:62432797-62432817 1.0000 20 chr11:76338081-76338101 1.0000 20 chr1:78148369-78148389 1.0000 20 chr19:12888544-12888564 1.0000 20 chr6:156973603-156973623 1.0000 20 chr16:18812842-18812862 1.0000 20 chr6:71122911-71122931 1.0000 20 chr21:36260539-36260559 1.0000 20 chrX:12993266-12993286 1.0000 20 chr17:27717325-27717345 1.0000 20 chr12:101389772-10138979 1.0000 20 chr20:45181833-45181853 1.0000 20 chr22:39632817-39632837 1.0000 20 chr3:171824996-171825016 1.0000 20 chr1:147735914-147735934 1.0000 20 chr11:81580921-81580941 1.0000 20 chr13:114634199-11463421 1.0000 20 chr17:40636500-40636520 1.0000 20 chr12:29534188-29534208 1.0000 20 chr10:12490891-12490911 1.0000 20 chr2:176032894-176032914 1.0000 20 chr3:49058886-49058906 1.0000 20 chr17:26605460-26605480 1.0000 20 chr11:14521366-14521386 1.0000 20 chr5:43484020-43484040 1.0000 20 chr14:75988781-75988801 1.0000 20 chr2:207630499-207630519 1.0000 20 chr13:31613574-31613594 1.0000 20 chr10:74033706-74033726 1.0000 20 chr17:40714111-40714131 1.0000 20 chr8:33371108-33371128 1.0000 20 chr20:1415686-1415706 1.0000 20 chr16:78795450-78795470 1.0000 20 chr8:101511716-101511736 1.0000 20 chr16:66556250-66556270 1.0000 20 chr7:100926426-100926446 1.0000 20 chr8:19554040-19554060 1.0000 20 chr12:1643033-1643053 1.0000 20 chr2:120517287-120517307 1.0000 20 chr9:88555915-88555935 1.0000 20 chr9:17863416-17863436 1.0000 20 chr14:98664925-98664945 1.0000 20 chr22:40357543-40357563 1.0000 20 chr1:40505639-40505659 1.0000 20 chr11:9623147-9623167 1.0000 20 chr5:118406700-118406720 1.0000 20 chrX:13003054-13003074 1.0000 20 chr8:22573398-22573418 1.0000 20 chr11:93474631-93474651 1.0000 20 chr10:8175248-8175268 1.0000 20 chr11:76383832-76383852 1.0000 20 chr18:54725320-54725340 1.0000 20 chr13:27825876-27825896 1.0000 20 chr5:133512613-133512633 1.0000 20 chrX:115029097-115029117 1.0000 20 chr1:210547436-210547456 1.0000 20 chr1:146556188-146556208 1.0000 20 chr10:96305406-96305426 1.0000 20 chr6:35995435-35995455 1.0000 20 chr6:7313622-7313642 1.0000 20 chr6:52161671-52161691 1.0000 20 chr1:35734321-35734341 1.0000 20 chr1:147806753-147806773 1.0000 20 chr12:6643686-6643706 1.0000 20 chr7:93717235-93717255 1.0000 20 chr1:101759171-101759191 1.0000 20 chr6:70295556-70295576 1.0000 20 chr20:30945864-30945884 1.0000 20 chr8:42249081-42249101 1.0000 20 chr12:27091408-27091428 1.0000 20 chr9:6681673-6681693 1.0000 20 chr6:31802681-31802701 1.0000 20 chrX:9431165-9431185 1.0000 20 chr2:242245024-242245044 1.0000 20 chr6:26273166-26273186 1.0000 20 chr5:179050623-179050643 1.0000 20 chr14:65695358-65695378 1.0000 20 chr10:70847862-70847882 1.0000 20 chr9:92114192-92114212 1.0000 20 chr5:60615844-60615864 1.0000 20 chr2:136743234-136743254 1.0000 20 chr8:81987036-81987056 1.0000 20 chr22:39632616-39632636 1.0000 20 chr6:52020974-52020994 1.0000 20 chr6:52021175-52021195 1.0000 20 chr15:78730379-78730399 1.0000 20 chr1:23885971-23885991 1.0000 20 chr3:48955909-48955929 1.0000 20 chr11:8704205-8704225 1.0000 20 chr21:36421504-36421524 1.0000 20 chr5:56469853-56469873 1.0000 20 chr9:116274701-116274721 1.0000 20 chr1:181128921-181128941 1.0000 20 chr3:15313465-15313485 1.0000 20 chr6:28317703-28317723 1.0000 20 chr6:137355188-137355208 1.0000 20 chr3:134013314-134013334 1.0000 20 chr12:116997097-11699711 1.0000 20 chr7:139044448-139044468 1.0000 20 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/GM12878/inference_raw/MEME/RankLinear0.6_10_CBFB/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/CBFB.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 5000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 5000 norand= no csites= 1000 Letter frequencies in dataset: A 0.217 C 0.268 G 0.284 T 0.231 Background letter frequencies (from file dataset with add-one prior applied): A 0.217 C 0.268 G 0.284 T 0.231 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF ACCACARN MEME-1 width = 8 sites = 54 llr = 384 E-value = 1.3e-034 ******************************************************************************** -------------------------------------------------------------------------------- Motif ACCACARN MEME-1 Description -------------------------------------------------------------------------------- Simplified A a::81a32 pos.-specific C :aa:9::3 probability G :::2::43 matrix T ::::::22 bits 2.2 2.0 ** * 1.8 *** * 1.5 *** * Relative 1.3 *** * Entropy 1.1 ****** (10.3 bits) 0.9 ****** 0.7 ****** 0.4 ****** 0.2 ******* 0.0 -------- Multilevel ACCACAGC consensus AG sequence T A -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACCACARN MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:181128921-181128941 4 1.50e-05 aca accacagc catttgacc chr3:72150019-72150039 9 1.50e-05 GGCACAAA ACCACAGC CACC chr1:31342086-31342106 2 1.50e-05 A ACCACAGC CCCCATCCCA chr9:138831385-138831405 3 1.50e-05 tc accacagc ccacactcac chr8:19554040-19554060 12 5.52e-05 TGGCTGAAAA ACCacagt a chr3:141217824-141217844 8 5.52e-05 AAGGCAA ACCACAGG AAGAT chr3:40226722-40226742 8 5.52e-05 TGGGTAA ACCACAGT AACTC chr6:32054630-32054650 12 5.52e-05 AGCCACTCTC ACCACAGT G chr6:10534113-10534133 6 5.52e-05 CTGCG ACCACAGG CAGGGGA chr7:35749232-35749252 8 5.52e-05 GTGGTTA ACCACAGT AGCCA chr3:56929005-56929025 1 5.52e-05 . ACCACAAC TTTTGCTTTT chr16:68390503-68390523 9 5.52e-05 TGGGGAAG ACCACAGG TTTC chr5:141397815-141397835 5 5.52e-05 caca accacaac cacaacca chr11:7597512-7597532 7 5.52e-05 CGTGTA ACCACAGT TCCCAC chr16:66556250-66556270 10 8.93e-05 GTGTCCCCA ACCACAAG CCA chr12:101389772-10138979 3 8.93e-05 CA ACCACAAT GGTCAATTGT chr14:88472786-88472806 1 8.93e-05 . accacaag cctgtactgC chr2:62541164-62541184 4 8.93e-05 GTG ACCACAGA GATAGCCTG chr11:191644-191664 12 8.93e-05 acaattgaaa accacaat g chr19:8634153-8634173 7 8.93e-05 cagttg accacaag ctgaat chr1:146556188-146556208 6 9.85e-05 ccact accacaaa ttatgca chr17:26605460-26605480 1 9.85e-05 . accacaaa ggaaaagact chr6:43693061-43693081 13 9.85e-05 CGGTGCCCAA ACCACAAA chr11:81580921-81580941 13 1.11e-04 tagtggccaa accacatc chr2:242383446-242383466 1 1.11e-04 . ACCACATC AGGCAGTTTC chr4:186086870-186086890 1 1.34e-04 . accacatt ttaaccactt chr3:71276186-71276206 8 1.34e-04 CTCCTGG ACCACATG AGAAG chr20:62199351-62199371 10 1.44e-04 CCAGAGGAA ACCACATA AAC chr2:152907627-152907647 9 1.44e-04 CCTCAAAA ACCACATA CAAT chr5:43484020-43484040 3 1.64e-04 AG ACCGCAGC GTCGGCCGAG chr21:36260539-36260559 1 1.64e-04 . ACCGCAGC AGGTGGAGCG chr1:35734321-35734341 11 2.16e-04 CCTTTAAGAA ACCGCAGG CG chr20:37433800-37433820 12 2.16e-04 GCGAGTCCAC ACCGCAGG C chr3:185869124-185869144 6 2.16e-04 GTGTG ACCGCAGG GAACAAC chr1:23039058-23039078 2 2.16e-04 G ACCGCAGT CAGGGGGTGG chr1:200177117-200177137 10 2.61e-04 acctccaaa accgcaga ata chr6:43603581-43603601 2 2.61e-04 A ACCGCAAG GAGTAGCGGA chr2:204463208-204463228 10 3.18e-04 ACCAAAAAT ACCAAAAC CTC chr6:30919819-30919839 11 3.18e-04 GACCATATGC ACCAAAGG GA chr1:101406886-101406906 8 3.18e-04 cattccc accaaaac cacct chr18:44472978-44472998 2 4.53e-04 t accacact gTGGTAGCTC chr7:129791673-129791693 3 4.75e-04 aa accacaca cacatcacac chr11:125757514-12575753 3 5.31e-04 AA ACCTCAGC GGTCGGCGGT chrX:115029097-115029117 1 6.08e-04 . accatagt ctccactaat chr16:18812842-18812862 2 9.02e-04 A ACCGAAAC CCGCACACCA chr5:133512613-133512633 6 1.05e-03 GAAAA ACCGAAGA CGAAGCC chr2:69875440-69875460 7 1.05e-03 cattac accatatg ggcttt chr15:70772729-70772749 8 1.05e-03 CCTCAAA GCCACAAA GAAAG chr1:17223037-17223057 5 1.17e-03 TCTC ACCTCATA GAGCCAGG chr10:121073401-12107342 8 1.17e-03 TTTGGAA ACCCCAAC TGTGT chr8:142012428-142012448 1 1.39e-03 . accagaag AACCCTCAAG chr21:36421504-36421524 13 1.48e-03 CTGCCTGCTG ACCACTAT chr2:68666153-68666173 7 1.55e-03 gaccat gccacatg tggagg chr20:45181833-45181853 6 1.60e-03 ggccc acaacatc cggaagg -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACCACARN MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:181128921-181128941 1.5e-05 3_[+1]_9 chr3:72150019-72150039 1.5e-05 8_[+1]_4 chr1:31342086-31342106 1.5e-05 1_[+1]_11 chr9:138831385-138831405 1.5e-05 2_[+1]_10 chr8:19554040-19554060 5.5e-05 11_[+1]_1 chr3:141217824-141217844 5.5e-05 7_[+1]_5 chr3:40226722-40226742 5.5e-05 7_[+1]_5 chr6:32054630-32054650 5.5e-05 11_[+1]_1 chr6:10534113-10534133 5.5e-05 5_[+1]_7 chr7:35749232-35749252 5.5e-05 7_[+1]_5 chr3:56929005-56929025 5.5e-05 [+1]_12 chr16:68390503-68390523 5.5e-05 8_[+1]_4 chr5:141397815-141397835 5.5e-05 4_[+1]_8 chr11:7597512-7597532 5.5e-05 6_[+1]_6 chr16:66556250-66556270 8.9e-05 9_[+1]_3 chr12:101389772-10138979 8.9e-05 2_[+1]_10 chr14:88472786-88472806 8.9e-05 [+1]_12 chr2:62541164-62541184 8.9e-05 3_[+1]_9 chr11:191644-191664 8.9e-05 11_[+1]_1 chr19:8634153-8634173 8.9e-05 6_[+1]_6 chr1:146556188-146556208 9.9e-05 5_[+1]_7 chr17:26605460-26605480 9.9e-05 [+1]_12 chr6:43693061-43693081 9.9e-05 12_[+1] chr11:81580921-81580941 0.00011 12_[+1] chr2:242383446-242383466 0.00011 [+1]_12 chr4:186086870-186086890 0.00013 [+1]_12 chr3:71276186-71276206 0.00013 7_[+1]_5 chr20:62199351-62199371 0.00014 9_[+1]_3 chr2:152907627-152907647 0.00014 8_[+1]_4 chr5:43484020-43484040 0.00016 2_[+1]_10 chr21:36260539-36260559 0.00016 [+1]_12 chr1:35734321-35734341 0.00022 10_[+1]_2 chr20:37433800-37433820 0.00022 11_[+1]_1 chr3:185869124-185869144 0.00022 5_[+1]_7 chr1:23039058-23039078 0.00022 1_[+1]_11 chr1:200177117-200177137 0.00026 9_[+1]_3 chr6:43603581-43603601 0.00026 1_[+1]_11 chr2:204463208-204463228 0.00032 9_[+1]_3 chr6:30919819-30919839 0.00032 10_[+1]_2 chr1:101406886-101406906 0.00032 7_[+1]_5 chr18:44472978-44472998 0.00045 1_[+1]_11 chr7:129791673-129791693 0.00047 2_[+1]_10 chr11:125757514-12575753 0.00053 2_[+1]_10 chrX:115029097-115029117 0.00061 [+1]_12 chr16:18812842-18812862 0.0009 1_[+1]_11 chr5:133512613-133512633 0.001 5_[+1]_7 chr2:69875440-69875460 0.001 6_[+1]_6 chr15:70772729-70772749 0.001 7_[+1]_5 chr1:17223037-17223057 0.0012 4_[+1]_8 chr10:121073401-12107342 0.0012 7_[+1]_5 chr8:142012428-142012448 0.0014 [+1]_12 chr21:36421504-36421524 0.0015 12_[+1] chr2:68666153-68666173 0.0016 6_[+1]_6 chr20:45181833-45181853 0.0016 5_[+1]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACCACARN MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ACCACARN width=8 seqs=54 chr1:181128921-181128941 ( 4) ACCACAGC 1 chr3:72150019-72150039 ( 9) ACCACAGC 1 chr1:31342086-31342106 ( 2) ACCACAGC 1 chr9:138831385-138831405 ( 3) ACCACAGC 1 chr8:19554040-19554060 ( 12) ACCACAGT 1 chr3:141217824-141217844 ( 8) ACCACAGG 1 chr3:40226722-40226742 ( 8) ACCACAGT 1 chr6:32054630-32054650 ( 12) ACCACAGT 1 chr6:10534113-10534133 ( 6) ACCACAGG 1 chr7:35749232-35749252 ( 8) ACCACAGT 1 chr3:56929005-56929025 ( 1) ACCACAAC 1 chr16:68390503-68390523 ( 9) ACCACAGG 1 chr5:141397815-141397835 ( 5) ACCACAAC 1 chr11:7597512-7597532 ( 7) ACCACAGT 1 chr16:66556250-66556270 ( 10) ACCACAAG 1 chr12:101389772-10138979 ( 3) ACCACAAT 1 chr14:88472786-88472806 ( 1) ACCACAAG 1 chr2:62541164-62541184 ( 4) ACCACAGA 1 chr11:191644-191664 ( 12) ACCACAAT 1 chr19:8634153-8634173 ( 7) ACCACAAG 1 chr1:146556188-146556208 ( 6) ACCACAAA 1 chr17:26605460-26605480 ( 1) ACCACAAA 1 chr6:43693061-43693081 ( 13) ACCACAAA 1 chr11:81580921-81580941 ( 13) ACCACATC 1 chr2:242383446-242383466 ( 1) ACCACATC 1 chr4:186086870-186086890 ( 1) ACCACATT 1 chr3:71276186-71276206 ( 8) ACCACATG 1 chr20:62199351-62199371 ( 10) ACCACATA 1 chr2:152907627-152907647 ( 9) ACCACATA 1 chr5:43484020-43484040 ( 3) ACCGCAGC 1 chr21:36260539-36260559 ( 1) ACCGCAGC 1 chr1:35734321-35734341 ( 11) ACCGCAGG 1 chr20:37433800-37433820 ( 12) ACCGCAGG 1 chr3:185869124-185869144 ( 6) ACCGCAGG 1 chr1:23039058-23039078 ( 2) ACCGCAGT 1 chr1:200177117-200177137 ( 10) ACCGCAGA 1 chr6:43603581-43603601 ( 2) ACCGCAAG 1 chr2:204463208-204463228 ( 10) ACCAAAAC 1 chr6:30919819-30919839 ( 11) ACCAAAGG 1 chr1:101406886-101406906 ( 8) ACCAAAAC 1 chr18:44472978-44472998 ( 2) ACCACACT 1 chr7:129791673-129791693 ( 3) ACCACACA 1 chr11:125757514-12575753 ( 3) ACCTCAGC 1 chrX:115029097-115029117 ( 1) ACCATAGT 1 chr16:18812842-18812862 ( 2) ACCGAAAC 1 chr5:133512613-133512633 ( 6) ACCGAAGA 1 chr2:69875440-69875460 ( 7) ACCATATG 1 chr15:70772729-70772749 ( 8) GCCACAAA 1 chr1:17223037-17223057 ( 5) ACCTCATA 1 chr10:121073401-12107342 ( 8) ACCCCAAC 1 chr8:142012428-142012448 ( 1) ACCAGAAG 1 chr21:36421504-36421524 ( 13) ACCACTAT 1 chr2:68666153-68666173 ( 7) GCCACATG 1 chr20:45181833-45181853 ( 6) ACAACATC 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACCACARN MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 5.68424 E= 1.3e-034 215 -1240 -293 -1240 -1240 190 -1240 -1240 -355 187 -1240 -1240 181 -385 -61 -264 -123 167 -393 -264 218 -1240 -1240 -364 62 -286 65 -32 -9 14 -3 -6 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACCACARN MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 54 E= 1.3e-034 0.962963 0.000000 0.037037 0.000000 0.000000 1.000000 0.000000 0.000000 0.018519 0.981481 0.000000 0.000000 0.759259 0.018519 0.185185 0.037037 0.092593 0.851852 0.018519 0.037037 0.981481 0.000000 0.000000 0.018519 0.333333 0.037037 0.444444 0.185185 0.203704 0.296296 0.277778 0.222222 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACCACARN MEME-1 regular expression -------------------------------------------------------------------------------- ACCACA[GA][CGTA] -------------------------------------------------------------------------------- Time 1.98 secs. ******************************************************************************** ******************************************************************************** MOTIF TGTGGTTW MEME-2 width = 8 sites = 37 llr = 303 E-value = 9.1e-030 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGTGGTTW MEME-2 Description -------------------------------------------------------------------------------- Simplified A 1:::::15 pos.-specific C ::2:::2: probability G 1a:aa::1 matrix T 9:8::a74 bits 2.2 * 2.0 * 1.8 * *** 1.5 * *** Relative 1.3 ****** Entropy 1.1 ****** (11.8 bits) 0.9 ******* 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGTGGTTA consensus CT sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGGTTW MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:6424074-6424094 6 1.42e-05 CAGGA TGTGGTTA GGGAGAG chr16:4817272-4817292 3 1.42e-05 AC TGTGGTTA ATGTGGTCCT chr4:38732881-38732901 10 1.42e-05 CGAGGTATC TGTGGTTA GAG chr3:72226980-72227000 7 1.42e-05 GGTTTC TGTGGTTA ACTCCG chrX:13003054-13003074 10 2.92e-05 TACCCAGAG Tgtggttt tca chr11:62432797-62432817 13 2.92e-05 AGCTAGTAAG TGTGGTTT chr1:172715589-172715609 12 2.92e-05 CTTATTCTGA TGTGGTTT T chr11:14786926-14786946 5 2.92e-05 TCAC TGTGGTTT TGGTGGTT chrX:99881055-99881075 3 2.92e-05 GC TGTGGTTT CCGAGGTTAA chr18:57588732-57588752 6 2.92e-05 GAAGC TGTGGTTT GTGGTTG chr15:40347064-40347084 6 2.92e-05 TGGTG TGTGGTTT CCCACAG chr8:98650874-98650894 5 2.92e-05 tgtg tgtgGTTT GTGGTTTG chr10:125532692-12553271 5 2.92e-05 TGGT TGTGGTTT TTATCTCT chr15:100259354-10025937 8 2.92e-05 gcattta tgtggttt tgtgg chr6:26273166-26273186 3 4.56e-05 CC TGTGGTCA TTTGACGGTA chr13:31613574-31613594 6 4.56e-05 tggtt tgtggtca cgaattt chr3:149198335-149198355 6 4.56e-05 TGTGT TGTGGTCA GCACTTC chr12:53599726-53599746 10 4.56e-05 CTGCATGCC TGTGGTCA GGG chr8:56901965-56901985 6 4.56e-05 TCTGG TGTGGTCA TAGGCAA chr1:165362452-165362472 4 4.56e-05 gtc tgtggtcA GAGATGGTT chr20:1415686-1415706 4 6.31e-05 gga tgtggtct acacaaagt chr3:191047080-191047100 13 9.81e-05 CACTCGCAAT TGCGGTTA chr19:5139400-5139420 10 9.81e-05 atgtgggag tgtggttg tgg chr16:57451081-57451101 2 9.81e-05 C TGCGGTTA GAAGGGCAAT chr10:90595547-90595567 1 1.16e-04 . TGCGGTTT CCACTAGGGG chr5:118406700-118406720 3 1.29e-04 GC TGTGGTAA AAAAGTGAAT chr6:16504336-16504356 9 1.29e-04 GCAAGAAA TGTGGTAA ATGT chr14:98664925-98664945 9 1.46e-04 GAGGAACT GGTGGTTA GTTT chr6:28317703-28317723 13 1.92e-04 CCGCCCTGCG GGTGGTTT chr10:12490891-12490911 2 1.92e-04 t ggtggttt tcttaacttc chr9:116341365-116341385 9 2.06e-04 GTGCAGGA AGTGGTTT TCGA chr7:91763155-91763175 5 2.47e-04 CTGC TGCGGTCA GTACAGAC chr1:205255872-205255892 2 2.98e-04 c tgtggtga gctgtggtga chr22:29225507-29225527 6 3.19e-04 GCCAA TGCGGTTG GCGATGG chr4:83214623-83214643 7 3.19e-04 ttggac tgcggttg accatg chr6:148525356-148525376 7 3.52e-04 AACCCT TGAGGTTT AAGAAG chr1:101759171-101759191 8 5.51e-04 TGAACCC AGTGGTTG CAGTG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGGTTW MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:6424074-6424094 1.4e-05 5_[+2]_7 chr16:4817272-4817292 1.4e-05 2_[+2]_10 chr4:38732881-38732901 1.4e-05 9_[+2]_3 chr3:72226980-72227000 1.4e-05 6_[+2]_6 chrX:13003054-13003074 2.9e-05 9_[+2]_3 chr11:62432797-62432817 2.9e-05 12_[+2] chr1:172715589-172715609 2.9e-05 11_[+2]_1 chr11:14786926-14786946 2.9e-05 4_[+2]_8 chrX:99881055-99881075 2.9e-05 2_[+2]_10 chr18:57588732-57588752 2.9e-05 5_[+2]_7 chr15:40347064-40347084 2.9e-05 5_[+2]_7 chr8:98650874-98650894 2.9e-05 4_[+2]_8 chr10:125532692-12553271 2.9e-05 4_[+2]_8 chr15:100259354-10025937 2.9e-05 7_[+2]_5 chr6:26273166-26273186 4.6e-05 2_[+2]_10 chr13:31613574-31613594 4.6e-05 5_[+2]_7 chr3:149198335-149198355 4.6e-05 5_[+2]_7 chr12:53599726-53599746 4.6e-05 9_[+2]_3 chr8:56901965-56901985 4.6e-05 5_[+2]_7 chr1:165362452-165362472 4.6e-05 3_[+2]_9 chr20:1415686-1415706 6.3e-05 3_[+2]_9 chr3:191047080-191047100 9.8e-05 12_[+2] chr19:5139400-5139420 9.8e-05 9_[+2]_3 chr16:57451081-57451101 9.8e-05 1_[+2]_11 chr10:90595547-90595567 0.00012 [+2]_12 chr5:118406700-118406720 0.00013 2_[+2]_10 chr6:16504336-16504356 0.00013 8_[+2]_4 chr14:98664925-98664945 0.00015 8_[+2]_4 chr6:28317703-28317723 0.00019 12_[+2] chr10:12490891-12490911 0.00019 1_[+2]_11 chr9:116341365-116341385 0.00021 8_[+2]_4 chr7:91763155-91763175 0.00025 4_[+2]_8 chr1:205255872-205255892 0.0003 1_[+2]_11 chr22:29225507-29225527 0.00032 5_[+2]_7 chr4:83214623-83214643 0.00032 6_[+2]_6 chr6:148525356-148525376 0.00035 6_[+2]_6 chr1:101759171-101759191 0.00055 7_[+2]_5 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGGTTW MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGTGGTTW width=8 seqs=37 chr11:6424074-6424094 ( 6) TGTGGTTA 1 chr16:4817272-4817292 ( 3) TGTGGTTA 1 chr4:38732881-38732901 ( 10) TGTGGTTA 1 chr3:72226980-72227000 ( 7) TGTGGTTA 1 chrX:13003054-13003074 ( 10) TGTGGTTT 1 chr11:62432797-62432817 ( 13) TGTGGTTT 1 chr1:172715589-172715609 ( 12) TGTGGTTT 1 chr11:14786926-14786946 ( 5) TGTGGTTT 1 chrX:99881055-99881075 ( 3) TGTGGTTT 1 chr18:57588732-57588752 ( 6) TGTGGTTT 1 chr15:40347064-40347084 ( 6) TGTGGTTT 1 chr8:98650874-98650894 ( 5) TGTGGTTT 1 chr10:125532692-12553271 ( 5) TGTGGTTT 1 chr15:100259354-10025937 ( 8) TGTGGTTT 1 chr6:26273166-26273186 ( 3) TGTGGTCA 1 chr13:31613574-31613594 ( 6) TGTGGTCA 1 chr3:149198335-149198355 ( 6) TGTGGTCA 1 chr12:53599726-53599746 ( 10) TGTGGTCA 1 chr8:56901965-56901985 ( 6) TGTGGTCA 1 chr1:165362452-165362472 ( 4) TGTGGTCA 1 chr20:1415686-1415706 ( 4) TGTGGTCT 1 chr3:191047080-191047100 ( 13) TGCGGTTA 1 chr19:5139400-5139420 ( 10) TGTGGTTG 1 chr16:57451081-57451101 ( 2) TGCGGTTA 1 chr10:90595547-90595567 ( 1) TGCGGTTT 1 chr5:118406700-118406720 ( 3) TGTGGTAA 1 chr6:16504336-16504356 ( 9) TGTGGTAA 1 chr14:98664925-98664945 ( 9) GGTGGTTA 1 chr6:28317703-28317723 ( 13) GGTGGTTT 1 chr10:12490891-12490911 ( 2) GGTGGTTT 1 chr9:116341365-116341385 ( 9) AGTGGTTT 1 chr7:91763155-91763175 ( 5) TGCGGTCA 1 chr1:205255872-205255892 ( 2) TGTGGTGA 1 chr22:29225507-29225527 ( 6) TGCGGTTG 1 chr4:83214623-83214643 ( 7) TGCGGTTG 1 chr6:148525356-148525376 ( 7) TGAGGTTT 1 chr1:101759171-101759191 ( 8) AGTGGTTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGGTTW MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.25552 E= 9.1e-030 -200 -1185 -181 190 -1185 -1185 182 -1185 -300 -73 -1185 181 -1185 -1185 182 -1185 -1185 -1185 182 -1185 -1185 -1185 -1185 211 -200 -31 -339 160 108 -1185 -139 90 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGGTTW MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 37 E= 9.1e-030 0.054054 0.000000 0.081081 0.864865 0.000000 0.000000 1.000000 0.000000 0.027027 0.162162 0.000000 0.810811 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.054054 0.216216 0.027027 0.702703 0.459459 0.000000 0.108108 0.432432 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGTGGTTW MEME-2 regular expression -------------------------------------------------------------------------------- TGTGGT[TC][AT] -------------------------------------------------------------------------------- Time 4.74 secs. ******************************************************************************** ******************************************************************************** MOTIF CTCGCGAK MEME-3 width = 8 sites = 8 llr = 75 E-value = 1.6e+002 ******************************************************************************** -------------------------------------------------------------------------------- Motif CTCGCGAK MEME-3 Description -------------------------------------------------------------------------------- Simplified A :::::1a: pos.-specific C a1a:a::: probability G :::a:9:5 matrix T :9:::::5 bits 2.2 * 2.0 * * * * 1.8 * *** * 1.5 ***** * Relative 1.3 ******* Entropy 1.1 ******* (13.5 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTCGCGAG consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCGCGAK MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr9:88555915-88555935 5 1.80e-05 CGGT CTCGCGAT CGTCTCTA chr6:97731122-97731142 10 1.80e-05 ACCAATCGC CTCGCGAT ATC chr10:75118557-75118577 13 1.80e-05 TATTCCAAGA CTCGCGAT chr5:56469853-56469873 11 4.01e-05 TGTGCACGAT CTCGCGAG AC chr20:30945864-30945884 5 4.01e-05 GCAC CTCGCGAG ACTCCACC chr17:53046053-53046073 4 4.01e-05 AAT CTCGCGAG GCGTGCTCC chr3:191047080-191047100 5 5.38e-05 GCCA CTCGCAAT TGCGGTTA chr4:15683254-15683274 9 1.17e-04 GCGGAAAT CCCGCGAG ACTG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCGCGAK MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr9:88555915-88555935 1.8e-05 4_[+3]_8 chr6:97731122-97731142 1.8e-05 9_[+3]_3 chr10:75118557-75118577 1.8e-05 12_[+3] chr5:56469853-56469873 4e-05 10_[+3]_2 chr20:30945864-30945884 4e-05 4_[+3]_8 chr17:53046053-53046073 4e-05 3_[+3]_9 chr3:191047080-191047100 5.4e-05 4_[+3]_8 chr4:15683254-15683274 0.00012 8_[+3]_4 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCGCGAK MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF CTCGCGAK width=8 seqs=8 chr9:88555915-88555935 ( 5) CTCGCGAT 1 chr6:97731122-97731142 ( 10) CTCGCGAT 1 chr10:75118557-75118577 ( 13) CTCGCGAT 1 chr5:56469853-56469873 ( 11) CTCGCGAG 1 chr20:30945864-30945884 ( 5) CTCGCGAG 1 chr17:53046053-53046073 ( 4) CTCGCGAG 1 chr3:191047080-191047100 ( 5) CTCGCAAT 1 chr4:15683254-15683274 ( 9) CCCGCGAG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCGCGAK MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.66267 E= 1.6e+002 -965 190 -965 -965 -965 -110 -965 192 -965 190 -965 -965 -965 -965 182 -965 -965 190 -965 -965 -79 -965 162 -965 221 -965 -965 -965 -965 -965 82 111 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCGCGAK MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 8 E= 1.6e+002 0.000000 1.000000 0.000000 0.000000 0.000000 0.125000 0.000000 0.875000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.125000 0.000000 0.875000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.500000 0.500000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif CTCGCGAK MEME-3 regular expression -------------------------------------------------------------------------------- CTCGCGA[GT] -------------------------------------------------------------------------------- Time 7.53 secs. ******************************************************************************** ******************************************************************************** MOTIF AAYTGAAA MEME-4 width = 8 sites = 2 llr = 22 E-value = 6.2e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif AAYTGAAA MEME-4 Description -------------------------------------------------------------------------------- Simplified A aa:::aaa pos.-specific C ::5::::: probability G ::::a::: matrix T ::5a:::: bits 2.2 ** * *** 2.0 ** * *** 1.8 ** ***** 1.5 ** ***** Relative 1.3 ** ***** Entropy 1.1 ******** (16.0 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AACTGAAA consensus T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAYTGAAA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:191644-191664 4 7.29e-06 tac aattgaaa accacaatg chr14:65676941-65676961 6 1.58e-05 caaag aactgaaa ctcccca -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAYTGAAA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:191644-191664 7.3e-06 3_[+4]_9 chr14:65676941-65676961 1.6e-05 5_[+4]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAYTGAAA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AAYTGAAA width=8 seqs=2 chr11:191644-191664 ( 4) AATTGAAA 1 chr14:65676941-65676961 ( 6) AACTGAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAYTGAAA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 10.6653 E= 6.2e+003 220 -765 -765 -765 220 -765 -765 -765 -765 89 -765 111 -765 -765 -765 211 -765 -765 181 -765 220 -765 -765 -765 220 -765 -765 -765 220 -765 -765 -765 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAYTGAAA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 2 E= 6.2e+003 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.500000 0.000000 0.500000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AAYTGAAA MEME-4 regular expression -------------------------------------------------------------------------------- AA[CT]TGAAA -------------------------------------------------------------------------------- Time 10.45 secs. ******************************************************************************** ******************************************************************************** MOTIF TGGTTCTT MEME-5 width = 8 sites = 3 llr = 33 E-value = 1.9e+004 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGGTTCTT MEME-5 Description -------------------------------------------------------------------------------- Simplified A :::::::: pos.-specific C :::::a:: probability G :aa::::: matrix T a::aa:aa bits 2.2 * ** ** 2.0 * ***** 1.8 ******** 1.5 ******** Relative 1.3 ******** Entropy 1.1 ******** (16.1 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGGTTCTT consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGTTCTT MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr15:70755662-70755682 6 1.42e-05 CAAAC TGGTTCTT GAAACTT chr15:45019400-45019420 2 1.42e-05 G TGGTTCTT TATTTTCACA chr11:120215243-12021526 6 1.42e-05 GGAAG TGGTTCTT GTGGGTG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGTTCTT MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr15:70755662-70755682 1.4e-05 5_[+5]_7 chr15:45019400-45019420 1.4e-05 1_[+5]_11 chr11:120215243-12021526 1.4e-05 5_[+5]_7 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGTTCTT MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGGTTCTT width=8 seqs=3 chr15:70755662-70755682 ( 6) TGGTTCTT 1 chr15:45019400-45019420 ( 2) TGGTTCTT 1 chr11:120215243-12021526 ( 6) TGGTTCTT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGTTCTT MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 9.73854 E= 1.9e+004 -823 -823 -823 211 -823 -823 181 -823 -823 -823 181 -823 -823 -823 -823 211 -823 -823 -823 211 -823 189 -823 -823 -823 -823 -823 211 -823 -823 -823 211 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGTTCTT MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 3 E= 1.9e+004 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGGTTCTT MEME-5 regular expression -------------------------------------------------------------------------------- TGGTTCTT -------------------------------------------------------------------------------- Time 11.73 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr19:8634153-8634173 1.25e-02 6_[+1(8.93e-05)]_6 chr9:123605277-123605297 5.75e-01 20 chr3:72226980-72227000 2.20e-02 6_[+2(1.42e-05)]_6 chr1:165362452-165362472 5.10e-02 3_[+2(4.56e-05)]_9 chr2:152907627-152907647 9.92e-02 20 chr12:49351329-49351349 6.57e-01 20 chr11:13484844-13484864 5.13e-01 20 chr11:7597512-7597532 7.33e-02 6_[+1(5.52e-05)]_6 chr16:57451081-57451101 2.61e-02 1_[+2(9.81e-05)]_11 chr9:138831385-138831405 2.27e-02 2_[+1(1.50e-05)]_10 chr11:120215243-12021526 3.41e-03 5_[+5(1.42e-05)]_7 chr5:141397815-141397835 4.24e-02 4_[+1(5.52e-05)]_8 chr20:62199351-62199371 2.57e-02 20 chr2:240189291-240189311 6.88e-01 20 chr7:91763155-91763175 1.48e-01 20 chr19:46149465-46149485 8.24e-01 20 chr7:5371148-5371168 3.55e-01 20 chr15:100259354-10025937 6.24e-03 7_[+2(2.92e-05)]_5 chr8:56901965-56901985 1.56e-02 5_[+2(4.56e-05)]_7 chr1:232941102-232941122 5.65e-01 20 chr15:70772729-70772749 1.58e-01 20 chr12:10396619-10396639 2.77e-01 20 chr17:4167292-4167312 3.81e-01 20 chr10:125532692-12553271 1.29e-03 4_[+2(2.92e-05)]_8 chr8:142046324-142046344 9.12e-01 20 chr3:56759449-56759469 1.42e-02 12_[+4(9.56e-05)] chr3:71276186-71276206 3.71e-02 20 chr18:44472978-44472998 6.76e-03 20 chr17:53046053-53046073 8.22e-02 3_[+3(4.01e-05)]_9 chr10:51565168-51565188 4.49e-01 20 chr2:228473515-228473535 2.98e-01 20 chr1:101406886-101406906 1.01e-01 20 chr1:31342086-31342106 4.08e-02 1_[+1(1.50e-05)]_11 chr11:123355357-12335537 9.37e-01 20 chr16:68390503-68390523 4.39e-02 8_[+1(5.52e-05)]_4 chr16:30672171-30672191 7.20e-01 20 chr10:121073401-12107342 1.47e-01 20 chr2:242383446-242383466 3.35e-02 20 chr11:125757514-12575753 3.32e-02 20 chr21:36238031-36238051 9.29e-01 20 chr9:116341365-116341385 9.72e-03 20 chr10:90595547-90595567 6.32e-02 20 chr9:15511373-15511393 3.21e-01 20 chr1:23039058-23039078 5.71e-02 20 chr3:56929005-56929025 1.82e-03 [+1(5.52e-05)]_12 chr3:49131526-49131546 9.86e-01 20 chr4:15683254-15683274 1.63e-01 20 chr16:81865496-81865516 5.09e-01 20 chr11:191644-191664 1.20e-04 3_[+4(7.29e-06)]_[+1(8.93e-05)]_1 chr9:102029026-102029046 2.34e-01 20 chr8:98650874-98650894 1.11e-02 4_[+2(2.92e-05)]_8 chr3:72150019-72150039 3.63e-02 8_[+1(1.50e-05)]_4 chr15:40347064-40347084 4.33e-02 5_[+2(2.92e-05)]_7 chr4:186086870-186086890 6.40e-02 20 chr15:59949657-59949677 2.45e-01 20 chr1:28496025-28496045 4.34e-01 20 chr7:35749232-35749252 2.87e-02 7_[+1(5.52e-05)]_5 chr7:129791673-129791693 2.59e-01 20 chr14:51342238-51342258 5.41e-01 20 chr17:65370917-65370937 7.00e-01 20 chr19:5139400-5139420 1.62e-02 9_[+2(9.81e-05)]_3 chr17:61776774-61776794 9.50e-01 20 chr6:44355268-44355288 8.49e-01 20 chr22:42000176-42000196 7.41e-01 20 chr19:47291790-47291810 9.08e-01 20 chr10:75118557-75118577 1.18e-02 12_[+3(1.80e-05)] chr4:83214623-83214643 2.11e-01 20 chr12:53599726-53599746 4.59e-02 9_[+2(4.56e-05)]_3 chr3:185869124-185869144 5.99e-02 20 chr1:183002530-183002550 1.18e-01 20 chr3:189807702-189807722 7.36e-01 20 chrX:41193428-41193448 2.84e-01 20 chr2:62541164-62541184 3.74e-02 3_[+1(8.93e-05)]_9 chr6:30919819-30919839 2.00e-01 20 chr3:105086884-105086904 3.27e-01 20 chr6:10534113-10534133 6.67e-02 5_[+1(5.52e-05)]_7 chr22:17568767-17568787 4.11e-01 20 chr2:69875440-69875460 1.25e-01 20 chr17:9292568-9292588 2.72e-01 20 chr22:30838594-30838614 3.92e-01 20 chr11:70270402-70270422 5.08e-01 20 chr6:32054630-32054650 5.34e-02 11_[+1(5.52e-05)]_1 chr16:87812864-87812884 5.57e-01 20 chr1:17222706-17222726 4.73e-01 20 chr14:65676941-65676961 2.56e-02 5_[+4(1.58e-05)]_7 chr6:86388406-86388426 9.19e-01 20 chr17:7760908-7760928 6.74e-01 20 chr9:98637902-98637922 4.39e-01 20 chr17:4843562-4843582 3.91e-01 20 chr1:167905779-167905799 9.33e-02 20 chr3:40226722-40226742 5.06e-02 7_[+1(5.52e-05)]_5 chr18:57588732-57588752 8.79e-03 5_[+2(2.92e-05)]_7 chr22:29225507-29225527 1.81e-02 20 chr10:1140426-1140446 2.38e-01 20 chr1:205255872-205255892 1.69e-01 20 chr4:38732881-38732901 2.06e-02 9_[+2(1.42e-05)]_3 chr6:43603581-43603601 5.61e-03 20 chr5:180230996-180231016 3.73e-01 20 chr6:97731122-97731142 1.05e-02 9_[+3(1.80e-05)]_3 chr22:22385398-22385418 5.75e-01 20 chr6:391788-391808 9.96e-01 20 chr6:17600552-17600572 2.71e-01 20 chr3:191047080-191047100 9.27e-05 4_[+3(5.38e-05)]_[+2(9.81e-05)] chr15:45019400-45019420 2.57e-02 1_[+5(1.42e-05)]_11 chr1:221886657-221886677 6.66e-01 20 chr15:66649015-66649035 8.79e-01 20 chr2:204463208-204463228 1.02e-01 20 chr14:31677597-31677617 5.51e-01 20 chr15:22833402-22833422 7.50e-01 20 chr20:10653391-10653411 8.36e-01 20 chr15:70755662-70755682 2.23e-03 5_[+5(1.42e-05)]_7 chr17:56525034-56525054 7.76e-01 20 chr11:118187478-11818749 4.42e-01 20 chrX:99881055-99881075 2.34e-02 2_[+2(2.92e-05)]_10 chr3:149198335-149198355 4.82e-02 5_[+2(4.56e-05)]_7 chr6:148525356-148525376 2.66e-02 20 chr6:5567742-5567762 1.26e-01 20 chr15:51369451-51369471 5.65e-01 20 chr14:88472786-88472806 3.93e-02 [+1(8.93e-05)]_12 chr1:44116174-44116194 3.31e-01 20 chr1:182573471-182573491 4.08e-01 20 chr20:37433800-37433820 1.00e-01 20 chr5:66502933-66502953 6.26e-01 20 chr2:160568953-160568973 8.24e-01 20 chr11:14786926-14786946 9.60e-03 4_[+2(2.92e-05)]_8 chr11:35167008-35167028 5.24e-01 20 chr6:16504336-16504356 1.74e-02 20 chr4:17812540-17812560 8.54e-01 20 chr17:18967127-18967147 4.01e-01 20 chr2:88315936-88315956 5.12e-01 20 chr16:4817272-4817292 6.14e-03 2_[+2(1.42e-05)]_10 chr11:73372135-73372155 5.28e-01 20 chr8:125538970-125538990 4.89e-01 20 chr1:17223037-17223057 2.46e-01 20 chr11:6424074-6424094 9.50e-03 5_[+2(1.42e-05)]_7 chr9:6413130-6413150 4.76e-01 20 chr21:45378498-45378518 6.63e-01 20 chr2:219773807-219773827 6.86e-01 20 chr6:43693061-43693081 3.47e-02 12_[+1(9.85e-05)] chr13:21750758-21750778 5.63e-01 20 chr15:85197545-85197565 9.13e-01 20 chr21:34084524-34084544 1.88e-01 20 chr1:161039733-161039753 7.01e-01 20 chr3:141217824-141217844 2.11e-02 7_[+1(5.52e-05)]_5 chr1:172715589-172715609 1.13e-02 11_[+2(2.92e-05)]_1 chr8:142012428-142012448 6.85e-02 20 chr10:21991950-21991970 4.02e-01 20 chr10:90145506-90145526 4.15e-01 20 chr17:56698677-56698697 7.95e-01 20 chr1:200177117-200177137 9.65e-02 20 chr2:68666153-68666173 1.58e-01 20 chr11:62432797-62432817 1.37e-02 12_[+2(2.92e-05)] chr11:76338081-76338101 6.38e-01 20 chr1:78148369-78148389 7.82e-01 20 chr19:12888544-12888564 8.04e-01 20 chr6:156973603-156973623 9.41e-01 20 chr16:18812842-18812862 9.59e-03 20 chr6:71122911-71122931 4.98e-01 20 chr21:36260539-36260559 7.38e-02 20 chrX:12993266-12993286 8.21e-01 20 chr17:27717325-27717345 7.70e-01 20 chr12:101389772-10138979 1.94e-03 2_[+1(8.93e-05)]_10 chr20:45181833-45181853 1.78e-01 20 chr22:39632817-39632837 8.50e-01 20 chr3:171824996-171825016 1.86e-01 20 chr1:147735914-147735934 4.44e-01 20 chr11:81580921-81580941 2.46e-02 20 chr13:114634199-11463421 6.95e-01 20 chr17:40636500-40636520 5.50e-01 20 chr12:29534188-29534208 8.92e-01 20 chr10:12490891-12490911 3.16e-02 20 chr2:176032894-176032914 9.75e-01 20 chr3:49058886-49058906 7.33e-01 20 chr17:26605460-26605480 6.50e-03 [+1(9.85e-05)]_12 chr11:14521366-14521386 9.74e-01 20 chr5:43484020-43484040 1.40e-01 20 chr14:75988781-75988801 2.90e-01 20 chr2:207630499-207630519 8.31e-01 20 chr13:31613574-31613594 4.32e-03 5_[+2(4.56e-05)]_7 chr10:74033706-74033726 7.11e-01 20 chr17:40714111-40714131 2.52e-01 20 chr8:33371108-33371128 4.82e-01 20 chr20:1415686-1415706 1.17e-02 3_[+2(6.31e-05)]_9 chr16:78795450-78795470 2.35e-01 20 chr8:101511716-101511736 4.33e-01 20 chr16:66556250-66556270 2.68e-02 9_[+1(8.93e-05)]_3 chr7:100926426-100926446 8.93e-01 20 chr8:19554040-19554060 1.58e-02 11_[+1(5.52e-05)]_1 chr12:1643033-1643053 4.51e-01 20 chr2:120517287-120517307 6.38e-01 20 chr9:88555915-88555935 3.74e-02 4_[+3(1.80e-05)]_8 chr9:17863416-17863436 3.18e-01 20 chr14:98664925-98664945 7.91e-03 20 chr22:40357543-40357563 3.84e-01 20 chr1:40505639-40505659 8.11e-01 20 chr11:9623147-9623167 8.00e-01 20 chr5:118406700-118406720 7.33e-03 20 chrX:13003054-13003074 3.41e-03 9_[+2(2.92e-05)]_3 chr8:22573398-22573418 4.32e-01 20 chr11:93474631-93474651 9.57e-01 20 chr10:8175248-8175268 6.46e-01 20 chr11:76383832-76383852 4.67e-01 20 chr18:54725320-54725340 1.38e-01 20 chr13:27825876-27825896 9.97e-01 20 chr5:133512613-133512633 1.26e-01 20 chrX:115029097-115029117 1.69e-01 20 chr1:210547436-210547456 4.49e-01 20 chr1:146556188-146556208 5.50e-02 5_[+1(9.85e-05)]_7 chr10:96305406-96305426 8.06e-01 20 chr6:35995435-35995455 8.62e-01 20 chr6:7313622-7313642 4.71e-01 20 chr6:52161671-52161691 5.96e-01 20 chr1:35734321-35734341 7.43e-02 20 chr1:147806753-147806773 3.43e-01 20 chr12:6643686-6643706 8.12e-01 20 chr7:93717235-93717255 1.66e-01 20 chr1:101759171-101759191 7.87e-02 20 chr6:70295556-70295576 7.11e-01 20 chr20:30945864-30945884 6.77e-02 4_[+3(4.01e-05)]_8 chr8:42249081-42249101 3.59e-01 20 chr12:27091408-27091428 8.62e-01 20 chr9:6681673-6681693 7.08e-01 20 chr6:31802681-31802701 8.83e-02 6_[+5(8.59e-05)]_6 chrX:9431165-9431185 7.36e-01 20 chr2:242245024-242245044 2.34e-01 20 chr6:26273166-26273186 4.44e-03 2_[+2(4.56e-05)]_10 chr5:179050623-179050643 6.33e-01 20 chr14:65695358-65695378 8.11e-01 20 chr10:70847862-70847882 4.38e-01 20 chr9:92114192-92114212 3.17e-01 20 chr5:60615844-60615864 8.32e-01 20 chr2:136743234-136743254 7.40e-01 20 chr8:81987036-81987056 5.85e-01 20 chr22:39632616-39632636 7.45e-01 20 chr6:52020974-52020994 6.69e-01 20 chr6:52021175-52021195 6.99e-01 20 chr15:78730379-78730399 8.88e-01 20 chr1:23885971-23885991 2.67e-01 20 chr3:48955909-48955929 7.66e-01 20 chr11:8704205-8704225 7.22e-01 20 chr21:36421504-36421524 3.43e-01 20 chr5:56469853-56469873 4.02e-02 10_[+3(4.01e-05)]_2 chr9:116274701-116274721 6.61e-01 20 chr1:181128921-181128941 1.55e-02 3_[+1(1.50e-05)]_9 chr3:15313465-15313485 8.15e-01 20 chr6:28317703-28317723 4.98e-02 20 chr6:137355188-137355208 3.22e-01 20 chr3:134013314-134013334 3.67e-01 20 chr12:116997097-11699711 2.28e-01 20 chr7:139044448-139044468 7.99e-01 20 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n09.farnam.hpc.yale.internal ********************************************************************************