******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 5.3.3 (Release date: Sun Feb 7 15:39:52 2021 -0800) For further information on how to interpret these results please access https://meme-suite.org/meme. To get a copy of the MEME Suite software please access https://meme-suite.org. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** PRIMARY SEQUENCES= ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/BACH1.fasta CONTROL SEQUENCES= --none-- ALPHABET= ACGT Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ chr16:1429095-1429115 1.0000 20 chr2:29353334-29353354 1.0000 20 chr10:73620345-73620365 1.0000 20 chr6:146134568-146134588 1.0000 20 chr6:84140897-84140917 1.0000 20 chr6:3002230-3002250 1.0000 20 chr2:102680872-102680892 1.0000 20 chr16:90062273-90062293 1.0000 20 chr9:108266357-108266377 1.0000 20 chr13:86239556-86239576 1.0000 20 chr9:134583249-134583269 1.0000 20 chr5:143155065-143155085 1.0000 20 chr12:48169435-48169455 1.0000 20 chr2:128165723-128165743 1.0000 20 chr16:89392602-89392622 1.0000 20 chr10:123670364-12367038 1.0000 20 chr2:203830646-203830666 1.0000 20 chr14:58637979-58637999 1.0000 20 chr15:80240739-80240759 1.0000 20 chr6:16852220-16852240 1.0000 20 chr17:78228746-78228766 1.0000 20 chr1:200609246-200609266 1.0000 20 chr2:8369895-8369915 1.0000 20 chr4:15151644-15151664 1.0000 20 chr16:90061498-90061518 1.0000 20 chr1:47817193-47817213 1.0000 20 chrX:15511403-15511423 1.0000 20 chr4:84469784-84469804 1.0000 20 chr2:157287737-157287757 1.0000 20 chr8:131012297-131012317 1.0000 20 chr19:16441413-16441433 1.0000 20 chr2:183418454-183418474 1.0000 20 chr7:100743596-100743616 1.0000 20 chr1:62212608-62212628 1.0000 20 chr11:1793929-1793949 1.0000 20 chr3:53304261-53304281 1.0000 20 chr7:107852088-107852108 1.0000 20 chr3:120397556-120397576 1.0000 20 chr11:61739497-61739517 1.0000 20 chr5:179247560-179247580 1.0000 20 chr2:214116492-214116512 1.0000 20 chr18:33268903-33268923 1.0000 20 chr10:67651269-67651289 1.0000 20 chr11:5301982-5302002 1.0000 20 chr6:146070921-146070941 1.0000 20 chr5:137937329-137937349 1.0000 20 chr10:7998652-7998672 1.0000 20 chr9:113019245-113019265 1.0000 20 chr3:156338214-156338234 1.0000 20 chr5:107008030-107008050 1.0000 20 chr19:47417240-47417260 1.0000 20 chr16:25060025-25060045 1.0000 20 chr6:41929610-41929630 1.0000 20 chr22:35768072-35768092 1.0000 20 chr1:225616537-225616557 1.0000 20 chr2:98487140-98487160 1.0000 20 chr16:57844375-57844395 1.0000 20 chr6:138043949-138043969 1.0000 20 chr21:47920562-47920582 1.0000 20 chr18:74189049-74189069 1.0000 20 chr20:8508826-8508846 1.0000 20 chr6:88433173-88433193 1.0000 20 chr11:65666859-65666879 1.0000 20 chr4:8305519-8305539 1.0000 20 chr17:58547258-58547278 1.0000 20 chr19:3671196-3671216 1.0000 20 chr10:64529483-64529503 1.0000 20 chr11:116943468-11694348 1.0000 20 chr8:109363837-109363857 1.0000 20 chr5:176839749-176839769 1.0000 20 chr15:44677385-44677405 1.0000 20 chr19:1249137-1249157 1.0000 20 chr13:78676717-78676737 1.0000 20 chr10:90792035-90792055 1.0000 20 chr7:83097748-83097768 1.0000 20 chr11:15991111-15991131 1.0000 20 chr6:158744454-158744474 1.0000 20 chr3:169862301-169862321 1.0000 20 chr19:34850470-34850490 1.0000 20 chr5:65020436-65020456 1.0000 20 chr19:54641674-54641694 1.0000 20 chr16:69760914-69760934 1.0000 20 chr6:138002279-138002299 1.0000 20 chr17:53167766-53167786 1.0000 20 chr1:204616837-204616857 1.0000 20 chr17:27685085-27685105 1.0000 20 chr17:66179122-66179142 1.0000 20 chr3:53787737-53787757 1.0000 20 chr1:26564191-26564211 1.0000 20 chr1:160696138-160696158 1.0000 20 chr16:10720002-10720022 1.0000 20 chr19:2841109-2841129 1.0000 20 chr2:243040835-243040855 1.0000 20 chr12:127568095-12756811 1.0000 20 chr3:98449356-98449376 1.0000 20 chr14:105144245-10514426 1.0000 20 chr5:102607824-102607844 1.0000 20 chr12:65550284-65550304 1.0000 20 chr5:90576437-90576457 1.0000 20 chr11:32109718-32109738 1.0000 20 chr12:87545182-87545202 1.0000 20 chr16:14595567-14595587 1.0000 20 chr1:154974250-154974270 1.0000 20 chr14:56666080-56666100 1.0000 20 chr2:220253313-220253333 1.0000 20 chr1:60196684-60196704 1.0000 20 chr6:34632263-34632283 1.0000 20 chr6:139265764-139265784 1.0000 20 chr16:18774279-18774299 1.0000 20 chrX:48797940-48797960 1.0000 20 chr6:52913356-52913376 1.0000 20 chr16:68298337-68298357 1.0000 20 chr16:15991796-15991816 1.0000 20 chr16:1429622-1429642 1.0000 20 chr11:64880101-64880121 1.0000 20 chr6:117187796-117187816 1.0000 20 chr1:21348965-21348985 1.0000 20 chr18:49251869-49251889 1.0000 20 chr21:30672621-30672641 1.0000 20 chr2:203500257-203500277 1.0000 20 chr20:10492380-10492400 1.0000 20 chr5:10689630-10689650 1.0000 20 chr7:130794748-130794768 1.0000 20 chr14:94476304-94476324 1.0000 20 chr2:28974498-28974518 1.0000 20 chr7:76009535-76009555 1.0000 20 chr14:72323052-72323072 1.0000 20 chr6:17703720-17703740 1.0000 20 chr2:65216352-65216372 1.0000 20 chr2:26291642-26291662 1.0000 20 chr20:62526434-62526454 1.0000 20 chr6:100059149-100059169 1.0000 20 chr16:47010663-47010683 1.0000 20 chr18:2655754-2655774 1.0000 20 chr12:80481787-80481807 1.0000 20 chr2:127822496-127822516 1.0000 20 chr15:51520825-51520845 1.0000 20 chr17:44026557-44026577 1.0000 20 chr5:140098422-140098442 1.0000 20 chr5:176103464-176103484 1.0000 20 chr19:10341239-10341259 1.0000 20 chr5:149380542-149380562 1.0000 20 chr17:38309768-38309788 1.0000 20 chr9:94860424-94860444 1.0000 20 chr18:9017265-9017285 1.0000 20 chr18:6414770-6414790 1.0000 20 chr9:31211173-31211193 1.0000 20 chr16:577326-577346 1.0000 20 chr17:79480127-79480147 1.0000 20 chr16:88703737-88703757 1.0000 20 chr15:48294024-48294044 1.0000 20 chr2:111926245-111926265 1.0000 20 chr1:228674476-228674496 1.0000 20 chr1:94375019-94375039 1.0000 20 chr12:6641869-6641889 1.0000 20 chr2:158336771-158336791 1.0000 20 chr4:48249365-48249385 1.0000 20 chr17:74230474-74230494 1.0000 20 chr1:90372358-90372378 1.0000 20 chr19:56159781-56159801 1.0000 20 chr6:119217796-119217816 1.0000 20 chr16:9141789-9141809 1.0000 20 chr6:27101659-27101679 1.0000 20 chr16:14597209-14597229 1.0000 20 chr5:94084943-94084963 1.0000 20 chr11:20385601-20385621 1.0000 20 chr13:114145186-11414520 1.0000 20 chr3:17225607-17225627 1.0000 20 chr8:84358537-84358557 1.0000 20 chr5:179246605-179246625 1.0000 20 chr9:137299295-137299315 1.0000 20 chr2:237488533-237488553 1.0000 20 chr19:49467202-49467222 1.0000 20 chr6:56819523-56819543 1.0000 20 chr3:159745782-159745802 1.0000 20 chr10:82895750-82895770 1.0000 20 chr12:72329544-72329564 1.0000 20 chr11:2959980-2960000 1.0000 20 chr16:88851980-88852000 1.0000 20 chr13:92000792-92000812 1.0000 20 chr9:69065206-69065226 1.0000 20 chr9:132333112-132333132 1.0000 20 chr1:1136962-1136982 1.0000 20 chr12:105352370-10535239 1.0000 20 chr17:19091412-19091432 1.0000 20 chr16:46865287-46865307 1.0000 20 chr12:120556360-12055638 1.0000 20 chr6:43739165-43739185 1.0000 20 chr6:106532518-106532538 1.0000 20 chr16:4357921-4357941 1.0000 20 chr17:56028309-56028329 1.0000 20 chr11:120204196-12020421 1.0000 20 chr6:4942583-4942603 1.0000 20 chr15:38856420-38856440 1.0000 20 chr15:52313434-52313454 1.0000 20 chr10:97550928-97550948 1.0000 20 chr19:2945312-2945332 1.0000 20 chr18:55254173-55254193 1.0000 20 chr19:50836777-50836797 1.0000 20 chr9:123964377-123964397 1.0000 20 chr14:34529527-34529547 1.0000 20 chr11:32728715-32728735 1.0000 20 chr4:186125113-186125133 1.0000 20 chr17:32295828-32295848 1.0000 20 chr9:5839475-5839495 1.0000 20 chr19:18451442-18451462 1.0000 20 chr2:29338364-29338384 1.0000 20 chr17:44178585-44178605 1.0000 20 chr12:6387986-6388006 1.0000 20 chr20:10457215-10457235 1.0000 20 chr3:149299710-149299730 1.0000 20 chr6:26066359-26066379 1.0000 20 chr4:139163594-139163614 1.0000 20 chr7:107886909-107886929 1.0000 20 chr16:50298387-50298407 1.0000 20 chr11:74517479-74517499 1.0000 20 chr6:90995531-90995551 1.0000 20 chr6:163834575-163834595 1.0000 20 chr17:62971721-62971741 1.0000 20 chr5:54040361-54040381 1.0000 20 chr2:10588513-10588533 1.0000 20 chr8:41347837-41347857 1.0000 20 chr3:98244554-98244574 1.0000 20 chr18:57585834-57585854 1.0000 20 chr2:220082684-220082704 1.0000 20 chr16:23838003-23838023 1.0000 20 chr16:66009177-66009197 1.0000 20 chr7:99841233-99841253 1.0000 20 chr4:129731056-129731076 1.0000 20 chr22:50964842-50964862 1.0000 20 chr1:1447588-1447608 1.0000 20 chr6:107435588-107435608 1.0000 20 chr14:32407124-32407144 1.0000 20 chr6:56755561-56755581 1.0000 20 chr17:18967153-18967173 1.0000 20 chr4:185189664-185189684 1.0000 20 chr17:18965553-18965573 1.0000 20 chr17:74118202-74118222 1.0000 20 chr19:1099656-1099676 1.0000 20 chr17:62631952-62631972 1.0000 20 chr4:8230460-8230480 1.0000 20 chr2:102697130-102697150 1.0000 20 chr1:147994375-147994395 1.0000 20 chr2:100106434-100106454 1.0000 20 chrX:1572499-1572519 1.0000 20 chr18:67704117-67704137 1.0000 20 chr15:100273524-10027354 1.0000 20 chr3:9932702-9932722 1.0000 20 chr12:16084877-16084897 1.0000 20 chr8:72743701-72743721 1.0000 20 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme -oc ../result/final_prediction/GM12878/inference_raw/MEME/RankLinear0.6_10_BACH1/ -dna -nmotifs 5 -w 8 -maxsize 250000 -nostatus ../result/final_prediction/GM12878/fasta/RankLinear0.6_10/BACH1.fasta model: mod= zoops nmotifs= 5 evt= inf objective function: em= E-value of product of p-values starts= E-value of product of p-values strands: + width: minw= 8 maxw= 8 nsites: minsites= 2 maxsites= 250 wnsites= 0.8 theta: spmap= uni spfuzz= 0.5 em: prior= dirichlet b= 0.01 maxiter= 50 distance= 1e-05 trim: wg= 11 ws= 1 endgaps= yes data: n= 5000 N= 250 sample: seed= 0 hsfrac= 0 searchsize= 5000 norand= no csites= 1000 Letter frequencies in dataset: A 0.235 C 0.265 G 0.277 T 0.222 Background letter frequencies (from file dataset with add-one prior applied): A 0.235 C 0.265 G 0.277 T 0.222 Background model order: 0 ******************************************************************************** ******************************************************************************** MOTIF MTGASTCA MEME-1 width = 8 sites = 55 llr = 463 E-value = 3.6e-067 ******************************************************************************** -------------------------------------------------------------------------------- Motif MTGASTCA MEME-1 Description -------------------------------------------------------------------------------- Simplified A 3::a:1:a pos.-specific C 5:::4:9: probability G 2:a:6::: matrix T :a:::91: bits 2.2 2.0 * * * * 1.7 *** * * 1.5 *** *** Relative 1.3 *** *** Entropy 1.1 *** *** (12.1 bits) 0.9 ******* 0.7 ******* 0.4 ******** 0.2 ******** 0.0 -------- Multilevel CTGAGTCA consensus A C sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTGASTCA MEME-1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr1:1136962-1136982 1 1.47e-05 . CTGAGTCA GCCCCGCGGG chr2:237488533-237488553 13 1.47e-05 GTAAAAAGTG CTGAGTCA chr17:74230474-74230494 13 1.47e-05 agtagaactg ctgagtca chr20:10492380-10492400 1 1.47e-05 . CTGAGTCA CCACACGGTG chr6:34632263-34632283 6 1.47e-05 TTTTG CTGAGTCA TTTCCTT chr5:90576437-90576457 5 1.47e-05 AGCG CTGAGTCA CGCTCGGC chr5:102607824-102607844 11 1.47e-05 AAACAAAATG CTGAGTCA TG chr3:53787737-53787757 7 1.47e-05 TTGTTG CTGAGTCA CCCTAG chr5:65020436-65020456 12 1.47e-05 gtgaaaattg ctgagtca t chr11:116943468-11694348 2 1.47e-05 G CTGAGTCA CAGTTTCCAA chr17:58547258-58547278 8 1.47e-05 gaaattg ctgagtca tacag chr16:57844375-57844395 8 1.47e-05 CTCAGTG CTGAGTCA TCGCC chr5:137937329-137937349 11 1.47e-05 GACTCTTGTG CTGAGTCA GA chr3:120397556-120397576 8 1.47e-05 AAAACTG CTGAGTCA CTATC chr13:86239556-86239576 5 1.47e-05 TGTG CTGAGTCA TGTTCCAC chr6:84140897-84140917 3 1.47e-05 CG CTGAGTCA TGGCAGGAGA chr6:56755561-56755581 11 4.17e-05 GTCACGCTTT CTGACTCA TC chr6:90995531-90995551 2 4.17e-05 C ATGAGTCA GCAAGCACTG chr10:97550928-97550948 2 4.17e-05 g atgagtca tatttaaaca chr15:52313434-52313454 9 4.17e-05 AAGGTTTG CTGACTCA GGGT chr16:14597209-14597229 5 4.17e-05 AGAG CTGACTCA TATGAGAA chr16:9141789-9141809 12 4.17e-05 GGAGGTCTGA ATGAGTCA G chr16:18774279-18774299 1 4.17e-05 . CTGACTCA AAGCGTCCTC chr7:100743596-100743616 12 4.17e-05 CCTGGGGAGC ATGAGTCA G chr16:66009177-66009197 13 5.41e-05 attaccctgc atgactca chr17:32295828-32295848 9 5.41e-05 TTGGCAAG ATGACTCA GCAA chr5:94084943-94084963 7 5.41e-05 CTGTGG ATGACTCA GCAAAA chr2:111926245-111926265 4 5.41e-05 GAT ATGACTCA GCACTTGGG chr1:204616837-204616857 2 5.41e-05 T ATGACTCA GCAGGAAGGA chr8:109363837-109363857 11 5.41e-05 gacttcaggc atgactca gc chr6:146070921-146070941 8 5.41e-05 TTTGAGT ATGACTCA GCTAT chr11:5301982-5302002 10 5.41e-05 TGACTCATC ATGACTCA GCA chr1:62212608-62212628 2 5.41e-05 A ATGACTCA GCATTTTCTA chr2:8369895-8369915 7 5.41e-05 aacagc atgactca gcaaag chr16:90062273-90062293 6 5.41e-05 CAGGG ATGACTCA GCAGGGA chr5:176103464-176103484 11 6.95e-05 ACAGtcagtt gtgagtca gc chr17:74118202-74118222 11 8.41e-05 TGCCCGGAAC GTGACTCA GC chr2:127822496-127822516 4 8.41e-05 AGA GTGACTCA GGGATTCGG chr14:105144245-10514426 9 8.41e-05 TCCGGAGC GTGACTCA GCAC chr17:66179122-66179142 8 8.41e-05 CTGTGCC GTGACTCA GGAAC chr2:203830646-203830666 6 8.41e-05 caaga gtgactca gcaaagt chr6:158744454-158744474 3 9.64e-05 AC CTGAGTTA GAGATAATTT chr6:3002230-3002250 2 9.64e-05 G CTGAGTTA GTCACTCAGC chr7:99841233-99841253 13 1.35e-04 cgtttccatt ctgagaca chr13:78676717-78676737 2 1.35e-04 G ATGAGTTA TTGCTGCATC chr9:137299295-137299315 4 1.48e-04 CTG CTGTGTCA CTGCACGCT chr15:80240739-80240759 11 1.48e-04 tgaGGGAAGG CTGTGTCA TG chr3:53304261-53304281 3 2.42e-04 TG CCGAGTCA TTGTGACTTG chr18:33268903-33268923 4 2.66e-04 AGC ATGACACA GCAAGTCTA chr10:90792035-90792055 4 3.22e-04 CAC CTTAGTCA TCCTTTCAC chr1:60196684-60196704 4 4.00e-04 atg ctgagtga tggagcaag chr3:17225607-17225627 12 5.35e-04 AGTTACTGAA GTGATTCA T chr16:1429095-1429115 13 5.35e-04 CGGCTCTGCC GTGACACA chr16:90061498-90061518 2 5.47e-04 C ATGACTCT GCAGAGATGA chr1:1447588-1447608 5 5.92e-04 GCGC GCGAGTCA GACTCGGG -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTGASTCA MEME-1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr1:1136962-1136982 1.5e-05 [+1]_12 chr2:237488533-237488553 1.5e-05 12_[+1] chr17:74230474-74230494 1.5e-05 12_[+1] chr20:10492380-10492400 1.5e-05 [+1]_12 chr6:34632263-34632283 1.5e-05 5_[+1]_7 chr5:90576437-90576457 1.5e-05 4_[+1]_8 chr5:102607824-102607844 1.5e-05 10_[+1]_2 chr3:53787737-53787757 1.5e-05 6_[+1]_6 chr5:65020436-65020456 1.5e-05 11_[+1]_1 chr11:116943468-11694348 1.5e-05 1_[+1]_11 chr17:58547258-58547278 1.5e-05 7_[+1]_5 chr16:57844375-57844395 1.5e-05 7_[+1]_5 chr5:137937329-137937349 1.5e-05 10_[+1]_2 chr3:120397556-120397576 1.5e-05 7_[+1]_5 chr13:86239556-86239576 1.5e-05 4_[+1]_8 chr6:84140897-84140917 1.5e-05 2_[+1]_10 chr6:56755561-56755581 4.2e-05 10_[+1]_2 chr6:90995531-90995551 4.2e-05 1_[+1]_11 chr10:97550928-97550948 4.2e-05 1_[+1]_11 chr15:52313434-52313454 4.2e-05 8_[+1]_4 chr16:14597209-14597229 4.2e-05 4_[+1]_8 chr16:9141789-9141809 4.2e-05 11_[+1]_1 chr16:18774279-18774299 4.2e-05 [+1]_12 chr7:100743596-100743616 4.2e-05 11_[+1]_1 chr16:66009177-66009197 5.4e-05 12_[+1] chr17:32295828-32295848 5.4e-05 8_[+1]_4 chr5:94084943-94084963 5.4e-05 6_[+1]_6 chr2:111926245-111926265 5.4e-05 3_[+1]_9 chr1:204616837-204616857 5.4e-05 1_[+1]_11 chr8:109363837-109363857 5.4e-05 10_[+1]_2 chr6:146070921-146070941 5.4e-05 7_[+1]_5 chr11:5301982-5302002 5.4e-05 9_[+1]_3 chr1:62212608-62212628 5.4e-05 1_[+1]_11 chr2:8369895-8369915 5.4e-05 6_[+1]_6 chr16:90062273-90062293 5.4e-05 5_[+1]_7 chr5:176103464-176103484 6.9e-05 10_[+1]_2 chr17:74118202-74118222 8.4e-05 10_[+1]_2 chr2:127822496-127822516 8.4e-05 3_[+1]_9 chr14:105144245-10514426 8.4e-05 8_[+1]_4 chr17:66179122-66179142 8.4e-05 7_[+1]_5 chr2:203830646-203830666 8.4e-05 5_[+1]_7 chr6:158744454-158744474 9.6e-05 2_[+1]_10 chr6:3002230-3002250 9.6e-05 1_[+1]_11 chr7:99841233-99841253 0.00013 12_[+1] chr13:78676717-78676737 0.00013 1_[+1]_11 chr9:137299295-137299315 0.00015 3_[+1]_9 chr15:80240739-80240759 0.00015 10_[+1]_2 chr3:53304261-53304281 0.00024 2_[+1]_10 chr18:33268903-33268923 0.00027 3_[+1]_9 chr10:90792035-90792055 0.00032 3_[+1]_9 chr1:60196684-60196704 0.0004 3_[+1]_9 chr3:17225607-17225627 0.00053 11_[+1]_1 chr16:1429095-1429115 0.00053 12_[+1] chr16:90061498-90061518 0.00055 1_[+1]_11 chr1:1447588-1447608 0.00059 4_[+1]_8 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTGASTCA MEME-1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF MTGASTCA width=8 seqs=55 chr1:1136962-1136982 ( 1) CTGAGTCA 1 chr2:237488533-237488553 ( 13) CTGAGTCA 1 chr17:74230474-74230494 ( 13) CTGAGTCA 1 chr20:10492380-10492400 ( 1) CTGAGTCA 1 chr6:34632263-34632283 ( 6) CTGAGTCA 1 chr5:90576437-90576457 ( 5) CTGAGTCA 1 chr5:102607824-102607844 ( 11) CTGAGTCA 1 chr3:53787737-53787757 ( 7) CTGAGTCA 1 chr5:65020436-65020456 ( 12) CTGAGTCA 1 chr11:116943468-11694348 ( 2) CTGAGTCA 1 chr17:58547258-58547278 ( 8) CTGAGTCA 1 chr16:57844375-57844395 ( 8) CTGAGTCA 1 chr5:137937329-137937349 ( 11) CTGAGTCA 1 chr3:120397556-120397576 ( 8) CTGAGTCA 1 chr13:86239556-86239576 ( 5) CTGAGTCA 1 chr6:84140897-84140917 ( 3) CTGAGTCA 1 chr6:56755561-56755581 ( 11) CTGACTCA 1 chr6:90995531-90995551 ( 2) ATGAGTCA 1 chr10:97550928-97550948 ( 2) ATGAGTCA 1 chr15:52313434-52313454 ( 9) CTGACTCA 1 chr16:14597209-14597229 ( 5) CTGACTCA 1 chr16:9141789-9141809 ( 12) ATGAGTCA 1 chr16:18774279-18774299 ( 1) CTGACTCA 1 chr7:100743596-100743616 ( 12) ATGAGTCA 1 chr16:66009177-66009197 ( 13) ATGACTCA 1 chr17:32295828-32295848 ( 9) ATGACTCA 1 chr5:94084943-94084963 ( 7) ATGACTCA 1 chr2:111926245-111926265 ( 4) ATGACTCA 1 chr1:204616837-204616857 ( 2) ATGACTCA 1 chr8:109363837-109363857 ( 11) ATGACTCA 1 chr6:146070921-146070941 ( 8) ATGACTCA 1 chr11:5301982-5302002 ( 10) ATGACTCA 1 chr1:62212608-62212628 ( 2) ATGACTCA 1 chr2:8369895-8369915 ( 7) ATGACTCA 1 chr16:90062273-90062293 ( 6) ATGACTCA 1 chr5:176103464-176103484 ( 11) GTGAGTCA 1 chr17:74118202-74118222 ( 11) GTGACTCA 1 chr2:127822496-127822516 ( 4) GTGACTCA 1 chr14:105144245-10514426 ( 9) GTGACTCA 1 chr17:66179122-66179142 ( 8) GTGACTCA 1 chr2:203830646-203830666 ( 6) GTGACTCA 1 chr6:158744454-158744474 ( 3) CTGAGTTA 1 chr6:3002230-3002250 ( 2) CTGAGTTA 1 chr7:99841233-99841253 ( 13) CTGAGACA 1 chr13:78676717-78676737 ( 2) ATGAGTTA 1 chr9:137299295-137299315 ( 4) CTGTGTCA 1 chr15:80240739-80240759 ( 11) CTGTGTCA 1 chr3:53304261-53304281 ( 3) CCGAGTCA 1 chr18:33268903-33268923 ( 4) ATGACACA 1 chr10:90792035-90792055 ( 4) CTTAGTCA 1 chr1:60196684-60196704 ( 4) CTGAGTGA 1 chr3:17225607-17225627 ( 12) GTGATTCA 1 chr16:1429095-1429115 ( 13) GTGACACA 1 chr16:90061498-90061518 ( 2) ATGACTCT 1 chr1:1447588-1447608 ( 5) GCGAGTCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTGASTCA MEME-1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 6.45611 E= 3.6e-067 48 94 -76 -1243 -1243 -286 -1243 211 -1243 -1243 182 -361 203 -1243 -1243 -261 -1243 66 102 -361 -211 -1243 -1243 209 -1243 181 -393 -203 206 -1243 -1243 -361 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTGASTCA MEME-1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 55 E= 3.6e-067 0.327273 0.509091 0.163636 0.000000 0.000000 0.036364 0.000000 0.963636 0.000000 0.000000 0.981818 0.018182 0.963636 0.000000 0.000000 0.036364 0.000000 0.418182 0.563636 0.018182 0.054545 0.000000 0.000000 0.945455 0.000000 0.927273 0.018182 0.054545 0.981818 0.000000 0.000000 0.018182 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif MTGASTCA MEME-1 regular expression -------------------------------------------------------------------------------- [CA]TGA[GC]TCA -------------------------------------------------------------------------------- Time 1.90 secs. ******************************************************************************** ******************************************************************************** MOTIF ACTCAGCA MEME-2 width = 8 sites = 12 llr = 121 E-value = 1.2e-007 ******************************************************************************** -------------------------------------------------------------------------------- Motif ACTCAGCA MEME-2 Description -------------------------------------------------------------------------------- Simplified A a::1a::9 pos.-specific C :8:9::a: probability G :2:::a:: matrix T ::a::::1 bits 2.2 * * * 2.0 * * *** 1.7 * * **** 1.5 * ****** Relative 1.3 ******** Entropy 1.1 ******** (14.6 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel ACTCAGCA consensus sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACTCAGCA MEME-2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr11:74517479-74517499 2 1.49e-05 g actcagca gtttctgttc chr9:5839475-5839495 1 1.49e-05 . ACTCAGCA GTTTGGGAAT chr9:132333112-132333132 2 1.49e-05 G ACTCAGCA GAAAATGAAG chr8:84358537-84358557 2 1.49e-05 g actcagca aaaacaaaga chr2:158336771-158336791 1 1.49e-05 . actcagca cattcccagc chr3:156338214-156338234 3 1.49e-05 tg actcagca ggtttggagc chr17:78228746-78228766 2 1.49e-05 g actcagca gttatgcttc chr10:123670364-12367038 3 1.49e-05 TG ACTCAGCA AAAAGCAAAG chr1:160696138-160696158 12 3.04e-05 TTGAGGTTTT AGTCAGCA T chr7:83097748-83097768 3 3.04e-05 TT AGTCAGCA TCATGCTGTG chr6:3002230-3002250 13 5.76e-05 TGAGTTAGTC ACTCAGCT chr6:146134568-146134588 10 5.76e-05 GAAACAGTG ACTAAGCA TGA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACTCAGCA MEME-2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr11:74517479-74517499 1.5e-05 1_[+2]_11 chr9:5839475-5839495 1.5e-05 [+2]_12 chr9:132333112-132333132 1.5e-05 1_[+2]_11 chr8:84358537-84358557 1.5e-05 1_[+2]_11 chr2:158336771-158336791 1.5e-05 [+2]_12 chr3:156338214-156338234 1.5e-05 2_[+2]_10 chr17:78228746-78228766 1.5e-05 1_[+2]_11 chr10:123670364-12367038 1.5e-05 2_[+2]_10 chr1:160696138-160696158 3e-05 11_[+2]_1 chr7:83097748-83097768 3e-05 2_[+2]_10 chr6:3002230-3002250 5.8e-05 12_[+2] chr6:146134568-146134588 5.8e-05 9_[+2]_3 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACTCAGCA MEME-2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF ACTCAGCA width=8 seqs=12 chr11:74517479-74517499 ( 2) ACTCAGCA 1 chr9:5839475-5839495 ( 1) ACTCAGCA 1 chr9:132333112-132333132 ( 2) ACTCAGCA 1 chr8:84358537-84358557 ( 2) ACTCAGCA 1 chr2:158336771-158336791 ( 1) ACTCAGCA 1 chr3:156338214-156338234 ( 3) ACTCAGCA 1 chr17:78228746-78228766 ( 2) ACTCAGCA 1 chr10:123670364-12367038 ( 3) ACTCAGCA 1 chr1:160696138-160696158 ( 12) AGTCAGCA 1 chr7:83097748-83097768 ( 3) AGTCAGCA 1 chr6:3002230-3002250 ( 13) ACTCAGCT 1 chr6:146134568-146134588 ( 10) ACTAAGCA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACTCAGCA MEME-2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.52481 E= 1.2e-007 209 -1023 -1023 -1023 -1023 165 -73 -1023 -1023 -1023 -1023 217 -149 179 -1023 -1023 209 -1023 -1023 -1023 -1023 -1023 185 -1023 -1023 192 -1023 -1023 196 -1023 -1023 -141 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACTCAGCA MEME-2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 12 E= 1.2e-007 1.000000 0.000000 0.000000 0.000000 0.000000 0.833333 0.166667 0.000000 0.000000 0.000000 0.000000 1.000000 0.083333 0.916667 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.916667 0.000000 0.000000 0.083333 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif ACTCAGCA MEME-2 regular expression -------------------------------------------------------------------------------- ACTCAGCA -------------------------------------------------------------------------------- Time 4.37 secs. ******************************************************************************** ******************************************************************************** MOTIF TGRAATTG MEME-3 width = 8 sites = 15 llr = 128 E-value = 5.8e-002 ******************************************************************************** -------------------------------------------------------------------------------- Motif TGRAATTG MEME-3 Description -------------------------------------------------------------------------------- Simplified A :369a1:: pos.-specific C :::::2:: probability G :741:::8 matrix T a::::7a2 bits 2.2 * * * 2.0 * * * 1.7 * ** * 1.5 * ** * Relative 1.3 * ** * Entropy 1.1 ***** ** (12.3 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TGAAATTG consensus AG C T sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGRAATTG MEME-3 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:130794748-130794768 10 1.09e-05 CGGATGGCT TGAAATTG CTG chr16:10720002-10720022 12 1.09e-05 catctaggag tgaaattg c chr17:27685085-27685105 13 1.09e-05 tacctaggag tgaaattg chr17:62631952-62631972 8 2.37e-05 ctaggaa tggaattg ctgag chr17:38309768-38309788 6 2.37e-05 aggaa tggaattg ctgagtc chr1:26564191-26564211 13 2.37e-05 tacttcagtg tggaattg chr18:57585834-57585854 10 3.30e-05 CTTTGGGCT TAAAATTG CCC chr15:44677385-44677405 11 5.47e-05 tacctagatg tgaaactg ct chr6:41929610-41929630 9 7.71e-05 acccaagc tgaaaatg ctga chr4:185189664-185189684 7 1.03e-04 agacag tggaactg tgtctg chr12:80481787-80481807 6 1.10e-04 acaac taaaattt tgaagaa chr4:48249365-48249385 3 1.64e-04 ca tagaattt tcgtatgact chr16:50298387-50298407 6 1.99e-04 atacc tgagattg aattgct chr17:74230474-74230494 5 1.99e-04 ggag tagaactg ctgagtca chr5:65020436-65020456 3 1.99e-04 ag tgaaaatt gctgagtcat -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGRAATTG MEME-3 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:130794748-130794768 1.1e-05 9_[+3]_3 chr16:10720002-10720022 1.1e-05 11_[+3]_1 chr17:27685085-27685105 1.1e-05 12_[+3] chr17:62631952-62631972 2.4e-05 7_[+3]_5 chr17:38309768-38309788 2.4e-05 5_[+3]_7 chr1:26564191-26564211 2.4e-05 12_[+3] chr18:57585834-57585854 3.3e-05 9_[+3]_3 chr15:44677385-44677405 5.5e-05 10_[+3]_2 chr6:41929610-41929630 7.7e-05 8_[+3]_4 chr4:185189664-185189684 0.0001 6_[+3]_6 chr12:80481787-80481807 0.00011 5_[+3]_7 chr4:48249365-48249385 0.00016 2_[+3]_10 chr16:50298387-50298407 0.0002 5_[+3]_7 chr17:74230474-74230494 0.0002 4_[+3]_8 chr5:65020436-65020456 0.0002 2_[+3]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGRAATTG MEME-3 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TGRAATTG width=8 seqs=15 chr7:130794748-130794768 ( 10) TGAAATTG 1 chr16:10720002-10720022 ( 12) TGAAATTG 1 chr17:27685085-27685105 ( 13) TGAAATTG 1 chr17:62631952-62631972 ( 8) TGGAATTG 1 chr17:38309768-38309788 ( 6) TGGAATTG 1 chr1:26564191-26564211 ( 13) TGGAATTG 1 chr18:57585834-57585854 ( 10) TAAAATTG 1 chr15:44677385-44677405 ( 11) TGAAACTG 1 chr6:41929610-41929630 ( 9) TGAAAATG 1 chr4:185189664-185189684 ( 7) TGGAACTG 1 chr12:80481787-80481807 ( 6) TAAAATTT 1 chr4:48249365-48249385 ( 3) TAGAATTT 1 chr16:50298387-50298407 ( 6) TGAGATTG 1 chr17:74230474-74230494 ( 5) TAGAACTG 1 chr5:65020436-65020456 ( 3) TGAAAATT 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGRAATTG MEME-3 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.42938 E= 5.8e-002 -1055 -1055 -1055 217 18 -1055 140 -1055 135 -1055 53 -1055 199 -1055 -205 -1055 209 -1055 -1055 -1055 -82 -41 -1055 158 -1055 -1055 -1055 217 -1055 -1055 153 -15 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGRAATTG MEME-3 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 15 E= 5.8e-002 0.000000 0.000000 0.000000 1.000000 0.266667 0.000000 0.733333 0.000000 0.600000 0.000000 0.400000 0.000000 0.933333 0.000000 0.066667 0.000000 1.000000 0.000000 0.000000 0.000000 0.133333 0.200000 0.000000 0.666667 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.800000 0.200000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TGRAATTG MEME-3 regular expression -------------------------------------------------------------------------------- T[GA][AG]AA[TC]T[GT] -------------------------------------------------------------------------------- Time 7.00 secs. ******************************************************************************** ******************************************************************************** MOTIF AGCTCWRA MEME-4 width = 8 sites = 10 llr = 88 E-value = 1.3e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif AGCTCWRA MEME-4 Description -------------------------------------------------------------------------------- Simplified A a::::54a pos.-specific C ::8:8::: probability G :a2:2:6: matrix T :::a:5:: bits 2.2 * * * 2.0 ** * * 1.7 ** * * 1.5 ** * * Relative 1.3 ** * * Entropy 1.1 ****** * (12.7 bits) 0.9 ******** 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel AGCTCAGA consensus G GTA sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGCTCWRA MEME-4 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr14:32407124-32407144 12 1.47e-05 ATACTGTGGG AGCTCTGA G chr18:9017265-9017285 3 1.47e-05 TG AGCTCTGA GCGGGCTGTG chr12:48169435-48169455 11 3.02e-05 AGCGTTTTAT AGCTCAGA AT chr1:90372358-90372378 6 4.26e-05 GTCAC AGCTCTAA CCTGCTG chr2:10588513-10588533 2 5.58e-05 C AGCTCAAA CCAGCCACGA chr2:214116492-214116512 10 5.58e-05 AGTGGGCTC AGCTCAAA AGA chr16:9141789-9141809 4 8.65e-05 CGG AGGTCTGA ATGAGTCAG chr14:94476304-94476324 3 8.65e-05 TG AGCTGTGA ACAGTGGTGA chr6:88433173-88433193 13 1.19e-04 agtgaaggga agctgaga chr7:107886909-107886929 13 1.72e-04 CAAAAGCCAA AGGTCAAA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGCTCWRA MEME-4 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr14:32407124-32407144 1.5e-05 11_[+4]_1 chr18:9017265-9017285 1.5e-05 2_[+4]_10 chr12:48169435-48169455 3e-05 10_[+4]_2 chr1:90372358-90372378 4.3e-05 5_[+4]_7 chr2:10588513-10588533 5.6e-05 1_[+4]_11 chr2:214116492-214116512 5.6e-05 9_[+4]_3 chr16:9141789-9141809 8.6e-05 3_[+4]_9 chr14:94476304-94476324 8.6e-05 2_[+4]_10 chr6:88433173-88433193 0.00012 12_[+4] chr7:107886909-107886929 0.00017 12_[+4] -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGCTCWRA MEME-4 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF AGCTCWRA width=8 seqs=10 chr14:32407124-32407144 ( 12) AGCTCTGA 1 chr18:9017265-9017285 ( 3) AGCTCTGA 1 chr12:48169435-48169455 ( 11) AGCTCAGA 1 chr1:90372358-90372378 ( 6) AGCTCTAA 1 chr2:10588513-10588533 ( 2) AGCTCAAA 1 chr2:214116492-214116512 ( 10) AGCTCAAA 1 chr16:9141789-9141809 ( 4) AGGTCTGA 1 chr14:94476304-94476324 ( 3) AGCTGTGA 1 chr6:88433173-88433193 ( 13) AGCTGAGA 1 chr7:107886909-107886929 ( 13) AGGTCAAA 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGCTCWRA MEME-4 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.5921 E= 1.3e+003 209 -997 -997 -997 -997 -997 185 -997 -997 159 -47 -997 -997 -997 -997 217 -997 159 -47 -997 109 -997 -997 117 77 -997 111 -997 209 -997 -997 -997 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGCTCWRA MEME-4 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 10 E= 1.3e+003 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.800000 0.200000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.800000 0.200000 0.000000 0.500000 0.000000 0.000000 0.500000 0.400000 0.000000 0.600000 0.000000 1.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif AGCTCWRA MEME-4 regular expression -------------------------------------------------------------------------------- AG[CG]T[CG][AT][GA]A -------------------------------------------------------------------------------- Time 9.50 secs. ******************************************************************************** ******************************************************************************** MOTIF TCATGCTG MEME-5 width = 8 sites = 7 llr = 66 E-value = 1.5e+003 ******************************************************************************** -------------------------------------------------------------------------------- Motif TCATGCTG MEME-5 Description -------------------------------------------------------------------------------- Simplified A ::a::::1 pos.-specific C :7::1a:1 probability G :3::9::7 matrix T a::a::a: bits 2.2 * ** * 2.0 * ** ** 1.7 * ** ** 1.5 * ** ** Relative 1.3 * ***** Entropy 1.1 ******* (13.6 bits) 0.9 ******* 0.7 ******** 0.4 ******** 0.2 ******** 0.0 -------- Multilevel TCATGCTG consensus G sequence -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCATGCTG MEME-5 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------- chr7:83097748-83097768 11 1.39e-05 TTAGTCAGCA TCATGCTG TG chr2:29353334-29353354 3 1.39e-05 AG TCATGCTG ACCAAGAAAT chr4:84469784-84469804 8 2.83e-05 TAGAGGC TGATGCTG GCGTG chr14:58637979-58637999 10 2.83e-05 ACTGCGACC TGATGCTG AGT chr5:140098422-140098442 2 4.01e-05 G TCATGCTA AAACACTGTT chr2:243040835-243040855 10 5.33e-05 CCTGCATAG TCATGCTC ACC chr12:6387986-6388006 3 6.66e-05 AC TCATCCTG GCGCCGCCCT -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCATGCTG MEME-5 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr7:83097748-83097768 1.4e-05 10_[+5]_2 chr2:29353334-29353354 1.4e-05 2_[+5]_10 chr4:84469784-84469804 2.8e-05 7_[+5]_5 chr14:58637979-58637999 2.8e-05 9_[+5]_3 chr5:140098422-140098442 4e-05 1_[+5]_11 chr2:243040835-243040855 5.3e-05 9_[+5]_3 chr12:6387986-6388006 6.7e-05 2_[+5]_10 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCATGCTG MEME-5 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF TCATGCTG width=8 seqs=7 chr7:83097748-83097768 ( 11) TCATGCTG 1 chr2:29353334-29353354 ( 3) TCATGCTG 1 chr4:84469784-84469804 ( 8) TGATGCTG 1 chr14:58637979-58637999 ( 10) TGATGCTG 1 chr5:140098422-140098442 ( 2) TCATGCTA 1 chr2:243040835-243040855 ( 10) TCATGCTC 1 chr12:6387986-6388006 ( 3) TCATCCTG 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCATGCTG MEME-5 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 4 w= 8 n= 3250 bayes= 8.69928 E= 1.5e+003 -945 -945 -945 217 -945 143 4 -945 209 -945 -945 -945 -945 -945 -945 217 -945 -89 163 -945 -945 191 -945 -945 -945 -945 -945 217 -72 -89 136 -945 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCATGCTG MEME-5 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 4 w= 8 nsites= 7 E= 1.5e+003 0.000000 0.000000 0.000000 1.000000 0.000000 0.714286 0.285714 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.142857 0.857143 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.142857 0.142857 0.714286 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif TCATGCTG MEME-5 regular expression -------------------------------------------------------------------------------- T[CG]ATGCTG -------------------------------------------------------------------------------- Time 10.22 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- chr16:1429095-1429115 5.76e-02 20 chr2:29353334-29353354 5.41e-03 2_[+5(1.39e-05)]_10 chr10:73620345-73620365 8.05e-01 20 chr6:146134568-146134588 1.38e-03 9_[+2(5.76e-05)]_3 chr6:84140897-84140917 2.19e-03 2_[+1(1.47e-05)]_10 chr6:3002230-3002250 2.46e-04 1_[+1(9.64e-05)]_3_[+2(5.76e-05)] chr2:102680872-102680892 7.63e-01 20 chr16:90062273-90062293 3.73e-05 8_[+2(1.49e-05)]_4 chr9:108266357-108266377 4.66e-01 20 chr13:86239556-86239576 1.87e-04 4_[+1(1.47e-05)]_8 chr9:134583249-134583269 9.55e-01 20 chr5:143155065-143155085 7.44e-01 20 chr12:48169435-48169455 2.05e-03 10_[+4(3.02e-05)]_2 chr2:128165723-128165743 9.62e-01 20 chr16:89392602-89392622 6.91e-01 20 chr10:123670364-12367038 8.50e-03 2_[+2(1.49e-05)]_10 chr2:203830646-203830666 6.28e-05 8_[+2(1.49e-05)]_4 chr14:58637979-58637999 5.50e-03 9_[+5(2.83e-05)]_3 chr15:80240739-80240759 3.16e-02 20 chr6:16852220-16852240 4.51e-01 20 chr17:78228746-78228766 8.41e-04 1_[+2(1.49e-05)]_11 chr1:200609246-200609266 3.36e-01 20 chr2:8369895-8369915 1.17e-04 9_[+2(1.49e-05)]_3 chr4:15151644-15151664 2.17e-01 20 chr16:90061498-90061518 4.72e-04 20 chr1:47817193-47817213 2.37e-02 20 chrX:15511403-15511423 6.87e-01 20 chr4:84469784-84469804 9.59e-03 7_[+5(2.83e-05)]_5 chr2:157287737-157287757 8.64e-01 20 chr8:131012297-131012317 5.56e-01 20 chr19:16441413-16441433 1.74e-01 20 chr2:183418454-183418474 1.44e-01 20 chr7:100743596-100743616 2.47e-02 11_[+1(4.17e-05)]_1 chr1:62212608-62212628 6.11e-05 4_[+2(1.49e-05)]_8 chr11:1793929-1793949 7.74e-01 20 chr3:53304261-53304281 4.49e-03 20 chr7:107852088-107852108 8.56e-01 20 chr3:120397556-120397576 2.04e-03 7_[+1(1.47e-05)]_5 chr11:61739497-61739517 4.13e-01 20 chr5:179247560-179247580 7.03e-01 20 chr2:214116492-214116512 6.79e-03 9_[+4(5.58e-05)]_3 chr18:33268903-33268923 2.23e-03 20 chr10:67651269-67651289 4.41e-01 20 chr11:5301982-5302002 8.23e-06 12_[+2(1.49e-05)] chr6:146070921-146070941 5.45e-05 7_[+1(5.41e-05)]_5 chr5:137937329-137937349 1.06e-03 10_[+1(1.47e-05)]_2 chr10:7998652-7998672 2.84e-01 20 chr9:113019245-113019265 7.80e-01 20 chr3:156338214-156338234 8.12e-03 2_[+2(1.49e-05)]_10 chr5:107008030-107008050 6.02e-01 20 chr19:47417240-47417260 5.51e-01 20 chr16:25060025-25060045 4.83e-01 20 chr6:41929610-41929630 9.33e-05 8_[+3(7.71e-05)]_4 chr22:35768072-35768092 5.22e-01 20 chr1:225616537-225616557 4.78e-01 20 chr2:98487140-98487160 6.28e-02 20 chr16:57844375-57844395 4.90e-04 7_[+1(1.47e-05)]_5 chr6:138043949-138043969 2.06e-01 20 chr21:47920562-47920582 5.77e-01 20 chr18:74189049-74189069 5.51e-01 20 chr20:8508826-8508846 7.04e-01 20 chr6:88433173-88433193 8.16e-03 20 chr11:65666859-65666879 3.18e-01 20 chr4:8305519-8305539 8.90e-01 20 chr17:58547258-58547278 1.13e-03 7_[+1(1.47e-05)]_5 chr19:3671196-3671216 9.98e-01 20 chr10:64529483-64529503 6.85e-01 20 chr11:116943468-11694348 1.61e-02 1_[+1(1.47e-05)]_11 chr8:109363837-109363857 1.05e-02 10_[+1(5.41e-05)]_2 chr5:176839749-176839769 5.10e-01 20 chr15:44677385-44677405 4.37e-04 10_[+3(5.47e-05)]_2 chr19:1249137-1249157 6.76e-01 20 chr13:78676717-78676737 1.58e-02 20 chr10:90792035-90792055 2.25e-03 20 chr7:83097748-83097768 1.46e-04 2_[+2(3.04e-05)]_[+5(1.39e-05)]_2 chr11:15991111-15991131 9.43e-01 20 chr6:158744454-158744474 1.73e-02 2_[+1(9.64e-05)]_10 chr3:169862301-169862321 6.22e-01 20 chr19:34850470-34850490 9.97e-01 20 chr5:65020436-65020456 8.11e-05 11_[+1(1.47e-05)]_1 chr19:54641674-54641694 3.05e-01 20 chr16:69760914-69760934 3.11e-02 20 chr6:138002279-138002299 5.01e-01 20 chr17:53167766-53167786 3.29e-03 20 chr1:204616837-204616857 3.49e-05 4_[+2(1.49e-05)]_8 chr17:27685085-27685105 4.68e-04 12_[+3(1.09e-05)] chr17:66179122-66179142 8.67e-04 7_[+1(8.41e-05)]_5 chr3:53787737-53787757 8.75e-05 6_[+1(1.47e-05)]_6 chr1:26564191-26564211 1.08e-02 12_[+3(2.37e-05)] chr1:160696138-160696158 4.90e-04 11_[+2(3.04e-05)]_1 chr16:10720002-10720022 7.46e-04 11_[+3(1.09e-05)]_1 chr19:2841109-2841129 9.98e-01 20 chr2:243040835-243040855 6.63e-03 9_[+5(5.33e-05)]_3 chr12:127568095-12756811 6.24e-01 20 chr3:98449356-98449376 1.06e-01 20 chr14:105144245-10514426 1.65e-04 11_[+2(1.49e-05)]_1 chr5:102607824-102607844 8.51e-04 10_[+1(1.47e-05)]_2 chr12:65550284-65550304 7.06e-01 20 chr5:90576437-90576457 7.14e-05 4_[+1(1.47e-05)]_8 chr11:32109718-32109738 4.34e-02 20 chr12:87545182-87545202 2.28e-01 20 chr16:14595567-14595587 2.77e-01 20 chr1:154974250-154974270 9.99e-01 20 chr14:56666080-56666100 3.26e-01 20 chr2:220253313-220253333 9.94e-01 20 chr1:60196684-60196704 1.78e-02 20 chr6:34632263-34632283 5.08e-04 5_[+1(1.47e-05)]_7 chr6:139265764-139265784 1.24e-01 20 chr16:18774279-18774299 4.09e-03 [+1(4.17e-05)]_12 chrX:48797940-48797960 6.21e-01 20 chr6:52913356-52913376 5.40e-01 20 chr16:68298337-68298357 9.03e-01 20 chr16:15991796-15991816 1.34e-01 20 chr16:1429622-1429642 5.12e-01 20 chr11:64880101-64880121 9.74e-01 20 chr6:117187796-117187816 1.83e-01 20 chr1:21348965-21348985 8.40e-01 20 chr18:49251869-49251889 4.14e-02 20 chr21:30672621-30672641 1.64e-01 20 chr2:203500257-203500277 7.73e-01 20 chr20:10492380-10492400 1.02e-03 [+1(1.47e-05)]_12 chr5:10689630-10689650 6.10e-03 20 chr7:130794748-130794768 1.16e-02 9_[+3(1.09e-05)]_3 chr14:94476304-94476324 4.63e-02 2_[+4(8.65e-05)]_10 chr2:28974498-28974518 3.84e-01 20 chr7:76009535-76009555 9.91e-01 20 chr14:72323052-72323072 2.68e-01 20 chr6:17703720-17703740 3.56e-01 20 chr2:65216352-65216372 8.30e-01 20 chr2:26291642-26291662 3.71e-01 20 chr20:62526434-62526454 9.48e-01 20 chr6:100059149-100059169 2.28e-01 20 chr16:47010663-47010683 1.73e-01 20 chr18:2655754-2655774 2.01e-01 20 chr12:80481787-80481807 1.38e-02 20 chr2:127822496-127822516 5.79e-03 3_[+1(8.41e-05)]_9 chr15:51520825-51520845 5.45e-01 20 chr17:44026557-44026577 9.36e-01 20 chr5:140098422-140098442 6.48e-03 1_[+5(4.01e-05)]_11 chr5:176103464-176103484 2.58e-04 10_[+1(6.95e-05)]_2 chr19:10341239-10341259 8.45e-01 20 chr5:149380542-149380562 1.00e+00 20 chr17:38309768-38309788 8.14e-03 5_[+3(2.37e-05)]_7 chr9:94860424-94860444 9.00e-02 20 chr18:9017265-9017285 7.70e-03 2_[+4(1.47e-05)]_10 chr18:6414770-6414790 9.94e-01 20 chr9:31211173-31211193 9.36e-02 20 chr16:577326-577346 9.68e-01 20 chr17:79480127-79480147 6.21e-01 20 chr16:88703737-88703757 2.08e-01 20 chr15:48294024-48294044 5.20e-01 20 chr2:111926245-111926265 6.27e-05 6_[+2(1.49e-05)]_6 chr1:228674476-228674496 9.95e-01 20 chr1:94375019-94375039 1.13e-01 20 chr12:6641869-6641889 7.11e-01 20 chr2:158336771-158336791 2.03e-02 [+2(1.49e-05)]_12 chr4:48249365-48249385 1.26e-01 20 chr17:74230474-74230494 1.44e-04 12_[+1(1.47e-05)] chr1:90372358-90372378 4.68e-03 5_[+4(4.26e-05)]_7 chr19:56159781-56159801 9.95e-01 20 chr6:119217796-119217816 2.05e-01 20 chr16:9141789-9141809 1.97e-04 3_[+4(8.65e-05)]_[+1(4.17e-05)]_1 chr6:27101659-27101679 7.99e-01 20 chr16:14597209-14597229 3.73e-03 4_[+1(4.17e-05)]_8 chr5:94084943-94084963 7.49e-05 9_[+2(1.49e-05)]_3 chr11:20385601-20385621 9.26e-01 20 chr13:114145186-11414520 9.34e-01 20 chr3:17225607-17225627 1.29e-01 20 chr8:84358537-84358557 1.32e-02 1_[+2(1.49e-05)]_11 chr5:179246605-179246625 3.75e-01 20 chr9:137299295-137299315 1.15e-02 20 chr2:237488533-237488553 2.32e-04 12_[+1(1.47e-05)] chr19:49467202-49467222 9.17e-01 20 chr6:56819523-56819543 6.71e-01 20 chr3:159745782-159745802 4.56e-01 20 chr10:82895750-82895770 8.39e-02 20 chr12:72329544-72329564 3.51e-02 20 chr11:2959980-2960000 1.57e-01 20 chr16:88851980-88852000 6.13e-01 20 chr13:92000792-92000812 1.00e+00 20 chr9:69065206-69065226 9.61e-01 20 chr9:132333112-132333132 5.16e-04 1_[+2(1.49e-05)]_11 chr1:1136962-1136982 2.79e-04 [+1(1.47e-05)]_12 chr12:105352370-10535239 3.92e-01 20 chr17:19091412-19091432 8.47e-01 20 chr16:46865287-46865307 9.72e-01 20 chr12:120556360-12055638 8.89e-01 20 chr6:43739165-43739185 8.43e-01 20 chr6:106532518-106532538 6.28e-01 20 chr16:4357921-4357941 3.66e-01 20 chr17:56028309-56028329 7.57e-01 20 chr11:120204196-12020421 7.19e-02 20 chr6:4942583-4942603 6.05e-01 20 chr15:38856420-38856440 8.50e-01 20 chr15:52313434-52313454 1.57e-03 8_[+1(4.17e-05)]_4 chr10:97550928-97550948 2.81e-03 1_[+1(4.17e-05)]_11 chr19:2945312-2945332 9.77e-01 20 chr18:55254173-55254193 6.03e-01 20 chr19:50836777-50836797 5.71e-01 20 chr9:123964377-123964397 9.46e-01 20 chr14:34529527-34529547 7.61e-01 20 chr11:32728715-32728735 5.98e-01 20 chr4:186125113-186125133 9.99e-01 20 chr17:32295828-32295848 1.03e-04 11_[+2(1.49e-05)]_1 chr9:5839475-5839495 9.19e-04 [+2(1.49e-05)]_12 chr19:18451442-18451462 8.19e-01 20 chr2:29338364-29338384 6.15e-01 20 chr17:44178585-44178605 4.48e-01 20 chr12:6387986-6388006 1.56e-02 2_[+5(6.66e-05)]_10 chr20:10457215-10457235 1.76e-01 20 chr3:149299710-149299730 1.00e-01 20 chr6:26066359-26066379 6.95e-01 20 chr4:139163594-139163614 4.04e-01 20 chr7:107886909-107886929 1.79e-01 20 chr16:50298387-50298407 1.16e-03 20 chr11:74517479-74517499 7.64e-03 1_[+2(1.49e-05)]_11 chr6:90995531-90995551 2.87e-05 4_[+2(3.04e-05)]_8 chr6:163834575-163834595 8.67e-01 20 chr17:62971721-62971741 9.98e-01 20 chr5:54040361-54040381 5.46e-01 20 chr2:10588513-10588533 3.03e-02 1_[+4(5.58e-05)]_11 chr8:41347837-41347857 7.44e-01 20 chr3:98244554-98244574 2.97e-01 20 chr18:57585834-57585854 2.09e-02 9_[+3(3.30e-05)]_3 chr2:220082684-220082704 8.73e-01 20 chr16:23838003-23838023 4.65e-01 20 chr16:66009177-66009197 3.81e-03 12_[+1(5.41e-05)] chr7:99841233-99841253 1.35e-02 20 chr4:129731056-129731076 1.00e+00 20 chr22:50964842-50964862 9.58e-01 20 chr1:1447588-1447608 7.11e-03 20 chr6:107435588-107435608 6.28e-01 20 chr14:32407124-32407144 1.09e-02 11_[+4(1.47e-05)]_1 chr6:56755561-56755581 9.51e-03 10_[+1(4.17e-05)]_2 chr17:18967153-18967173 5.00e-01 20 chr4:185189664-185189684 1.86e-03 20 chr17:18965553-18965573 4.40e-01 20 chr17:74118202-74118222 3.74e-02 10_[+1(8.41e-05)]_2 chr19:1099656-1099676 4.70e-01 20 chr17:62631952-62631972 1.45e-02 7_[+3(2.37e-05)]_5 chr4:8230460-8230480 8.46e-01 20 chr2:102697130-102697150 1.50e-01 20 chr1:147994375-147994395 2.30e-01 20 chr2:100106434-100106454 7.52e-01 20 chrX:1572499-1572519 8.57e-01 20 chr18:67704117-67704137 3.91e-01 20 chr15:100273524-10027354 9.23e-01 20 chr3:9932702-9932722 8.67e-01 20 chr12:16084877-16084897 4.50e-01 20 chr8:72743701-72743721 5.91e-01 20 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because requested number of motifs (5) found. ******************************************************************************** CPU: c17n10.farnam.hpc.yale.internal ********************************************************************************